Extracellular polymeric substances(EPS)constitutes crucial elements within bacterial biofilms,facili-tating accelerated antimicrobial resistance and conferring defense against the host's immune cells.Developing pr...Extracellular polymeric substances(EPS)constitutes crucial elements within bacterial biofilms,facili-tating accelerated antimicrobial resistance and conferring defense against the host's immune cells.Developing precise and effective antibiofilm approaches and strategies,tailored to the specific charac-teristics of EPS composition,can offer valuable insights for the creation of novel antimicrobial drugs.This,in turn,holds the potential to mitigate the alarming issue of bacterial drug resistance.Current analysis of EPS compositions relies heavily on colorimetric approaches with a significant bias,which is likely due to the selection of a standard compound and the cross-interference of various EPS compounds.Considering the pivotal role of EPS in biofilm functionality,it is imperative for EPS research to delve deeper into the analysis of intricate compositions,moving beyond the current focus on polymeric materials.This ne-cessitates a shift from heavy reliance on colorimetric analytic methods to more comprehensive and nuanced analytical approaches.In this study,we have provided a comprehensive summary of existing analytical methods utilized in the characterization of EPS compositions.Additionally,novel strategies aimed at targeting EPS to enhance biofilm penetration were explored,with a specific focus on high-lighting the limitations associated with colorimetric methods.Furthermore,we have outlined the challenges faced in identifying additional components of EPS and propose a prospective research plan to address these challenges.This review has the potential to guide future researchers in the search for novel compounds capable of suppressing EPS,thereby inhibiting biofilm formation.This insight opens up a new avenue for exploration within this research domain.展开更多
In response to the United Nations Sustainable Development Goals and China’s“Dual Carbon”Goals(DCGs means the goals of“Carbon Peak and carbon neutrality”),this paper from the perspective of the construction of Ch...In response to the United Nations Sustainable Development Goals and China’s“Dual Carbon”Goals(DCGs means the goals of“Carbon Peak and carbon neutrality”),this paper from the perspective of the construction of China’s Innovation Demonstration Zones for Sustainable Development Agenda(IDZSDAs),combines carbon emission-related metrics to construct a comprehensive assessment system for Urban Sustainable Development Capacity(USDC).After obtaining USDC assessment results through the assessment system,an approach combining Least Absolute Shrinkage and Selection Operator(LASSO)regression and Random Forest(RF)based on machine learning is proposed for identifying influencing factors and characterizing key issues.Combining Coupling Coordination Degree(CCD)analysis,the study further summarizes the systemic patterns and future directions of urban sustainable development.A case study on the IDZSDAs from 2015 to 2022 reveals that:(1)the combined identification method based on machine learning and CCD models effectively quantifies influencing factors and key issues in the urban sustainable development process;(2)the correspondence between influencing factors and key subsystems identified by the LASSO-RF combination model is generally consistent with the development situations in various cities;and(3)the machine learning-based combined recognition method is scalable and dynamic.It enables decision-makers to accurately identify influencing factors and characterize key issues based on actual urban development needs.展开更多
Restriction endonuclease analysis(REA),or restriction fragment length polymorphism(RFLP),was useful for identifying and determining the relatedness and putative identities of microbial strains(Tang et al.,1997)and for...Restriction endonuclease analysis(REA),or restriction fragment length polymorphism(RFLP),was useful for identifying and determining the relatedness and putative identities of microbial strains(Tang et al.,1997)and for characterizing and discriminating large numbers of samples inexpensively in the past。展开更多
In order to establish the quantitative relationship between equivalent strain and the performance index of the deformed material within the range of certain passes for equal channel angular processing （ECAP）, a new ...In order to establish the quantitative relationship between equivalent strain and the performance index of the deformed material within the range of certain passes for equal channel angular processing （ECAP）, a new approach to characterize the equivalent strain was proposed. The results show that there exists better accordance between mechanical property （such as hardness or strength） and equivalent strain after rolling and ECAP in a certain range of deformation amount, and Gauss equation can be satisfied among the equivalent strain and the mechanical properties for ECAP. Through regression analysis on the data of hardness and strength after the deformation, a more generalized expression of equivalent strain for ECAP is proposed as：ε=k0exp[-（k1M-k2）^2], where M is the strength or hardness of the material, k1 is the modified coefficient （k1∈ （0, 1））, ko and k2 are two parameters dependent on the critical strain and mechanical property that reaches saturation state for the material, respectively. In this expression the equivalent strain for ECAP is characterized novelly through the mechanical parameter relating to material property rather than the classical geometry equation.展开更多
Two measurement techniques are investigated to characterize photodetector linearity. A model for the two-tone and three-tone photodetector systems is developed to thoroughly investigate the influences of setup compone...Two measurement techniques are investigated to characterize photodetector linearity. A model for the two-tone and three-tone photodetector systems is developed to thoroughly investigate the influences of setup components on the measurement results. We demonstrate that small bias shifts from the quadrature point of the modulator will induce deviation into measurement results of the two-tone system, and the simulation results correspond well to experimental and calculation results.展开更多
An enhanced small-signal model is introduced to model the influence of the impact ionization effect on the performance of In As/Al Sb HFET, in which an optimized fitting function D（ωτi） in the form of least square...An enhanced small-signal model is introduced to model the influence of the impact ionization effect on the performance of In As/Al Sb HFET, in which an optimized fitting function D（ωτi） in the form of least square approximation is proposed in order to further enhance the accuracy in modeling the frequency dependency of the impact ionization effect.The enhanced model with D（ωτi） can accurately characterize the key S parameters of In As/Al Sb HFET in a wide frequency range with a very low error function EF. It is demonstrated that the new fitting function D（ωτi） is helpful in further improving the modeling accuracy degree.展开更多
Surface-enhanced Raman Spectroscopy(SERS)has been used to characterize hurnic substances.By using HNO_3 -roughened silver foils as the enhancing surface,both fluorescence quenching and strong SERS signals have been ob...Surface-enhanced Raman Spectroscopy(SERS)has been used to characterize hurnic substances.By using HNO_3 -roughened silver foils as the enhancing surface,both fluorescence quenching and strong SERS signals have been observed at the same time.The results obtained herein show that SERS is a particularly sensitive and highly selective technique for the characterization of humic substances in the environment. Humic substances axe receiving ever-inereasing attention because of their importance in the environment. Very recently,we have reported the first successful application of Raman spectroscopy for characterizing humic substances.In this present paper,the application of surface-enhanced Raman spectroscopy(SERS)for humic substances has further been investigated.To our knowledge,no such studies have previously been reported.The results obtained herein dearly demonstrate that SERS has a great deal of promise as an analytical method for“In Situ”characterizing humic substances in the environment.展开更多
The occurrence of hydrocarbon migration in petroliferous basins depends on the balance of driving force and resistance of carriers, which restricts mostly the quantity and positions of hydrocarbon accumulation. The dr...The occurrence of hydrocarbon migration in petroliferous basins depends on the balance of driving force and resistance of carriers, which restricts mostly the quantity and positions of hydrocarbon accumulation. The driving forces of hydrocarbon migration have been quantitatively studied, whereas the migration pathways and carriers were only qualitatively discussed up to now. Establishing a compound hydrocarbon carrier system and quantitatively characterizing its transport capability are significant for understanding the dynamic process of hydrocarbon migration and revealing the hydrocarbon accumulation characteristics. It has become an innovatory trend and also a difficult topic in study of hydrocarbon migration. In this article, a method is described for using displacement pressure to quantitatively characterize the transport capability of the compound carrier system, which composed of sandstone carriers, unconformities and faults. When the weathered and leached zone rarely developed, the basal conglomerate or transgressive sandstone of unconformities can be treated as part of sandstone carriers. An empirical relationship among core porosity, air permeability, and the pore aperture radius corresponding to a mercury saturation of 10% （r 10 ） can be obtained by multiple regression. Using porosity and permeability inversed by seismic data, the displacement pressure of sandstone carriers can be calculated by the empirical relationship and Washburn Equation. Displacement pressure of fault plane can be estimated by the regression formula between fault opening index （FOI） and hydrocarbon column height it can support. This method is applied in the eastern part of south slope in Dongying （东营） depression, Bohai （渤海） Bay Basin, China, to quantitatively characterize thetransport capability of the compound carrier system of Shahejie （沙河街） Formation. The results have good agreement with data from drilling wells. This method may be a step further in study of compound hydrocarbon carrier system in petroliferous basins. It may provide the basis of coupling expulsion quantity, migration driving force and hydrocarbon carrier system to simulate hydrocarbon migration and accumulation. Therefore this will help predict hydrocarbon migration pathways and the locations ofhydrocarbon accumulation.展开更多
Based on the massive data collected with a passive network monitoring equipment placed in China＇s backbone, we present a deep insight into the network backbone traffic and evaluate various ways for inproving traffic ...Based on the massive data collected with a passive network monitoring equipment placed in China＇s backbone, we present a deep insight into the network backbone traffic and evaluate various ways for inproving traffic classifying efficiency in this pa- per. In particular, the study has scrutinized the net- work traffic in terms of protocol types and signatures, flow length, and port distffoution, from which mean- ingful and interesting insights on the current Intemet of China from the perspective of both the packet and flow levels are derived. We show that the classifica- tion efficiency can be greatly irrproved by using the information of preferred ports of the network applica- tions. Quantitatively, we find two traffic duration thresholds, with which 40% of TCP flows and 70% of UDP flows can be excluded from classification pro- cessing while the in^act on classification accuracy is trivial, i.e., the classification accuracy can still reach a high level by saving 85% of the resources.展开更多
Contrast-enhanced ultrasound(CEUS)is a new form of ultrasound(US)that can dynamically display microvessels in a highly sensitive manner.The purpose of this study was to investigate the efficacy of CEUS for characteriz...Contrast-enhanced ultrasound(CEUS)is a new form of ultrasound(US)that can dynamically display microvessels in a highly sensitive manner.The purpose of this study was to investigate the efficacy of CEUS for characterizing testicular lesions in comparison with conventional US.Forty-seven patients with testicular lesions were enrolled.The histopathology results revealed that 31 cases were neoplastic(11 cases of seminomas,8 nonseminomatous germ cell tumors,8 lymphomas,2 Leydig cell tumors,and 2 nonspecific tumors),and 16 cases were nonneoplastic(8 cases of infarctions,3 epidermoid cysts,and 5 inflammation).The indicators of shallow lobulated morphology and cystic-solid echogenicity on conventional US were suggestive of germ cell tumors.More indicators on CEUS were found to be useful for characterizing testicular lesions.All the neoplastic lesions showed hyperenhancement on CEUS.Moreover,germ cell tumors presented with heterogeneous enhancement(73.7%,14/19),a twisted blood vessel pattern,rapid wash-in and wash-out,and peripheral rim hyperenhancement signs.Lymphoma was characterized by nonbranching linear vessel patterns(87.5%,7/8),rapid wash-in and slow wash-out.In nonneoplastic lesions,infarction and epidermoid cysts showed no enhancement,and abscesses were observed with marginal irregular enhancement.The sensitivity,specificity,and accuracy of CEUS for differentiating between neoplastic and nonneoplastic lesions were 100%,93.8%,and 97.9%,respectively,and these values were higher than those for conventional US(90.3%,62.5%,and 80.9%,respectively).CEUS can sensitively reflect the microvascular perfusion in testicular lesions and offers high accuracy for characterizing them.展开更多
With enormous growth of the number of Internet users and appearance of new applications, characterization of Internet traffic has attracted more and more attention and has become one of the major challenging issues in...With enormous growth of the number of Internet users and appearance of new applications, characterization of Internet traffic has attracted more and more attention and has become one of the major challenging issues in telecommunication network over the past few years. In this paper, we study the network traffic pattern of the aggregate traffic and of specific application traffic, especially the popular applications such as P2P, VoIP that contribute most network traffic. Our study verified that majority Internet backbone traffic is contributed by a small portion of users and a power function can be used to approximate the contribution of each user to the overall traffic. We show that P2P applications are the dominant traffic contributor in current Internet Backbone of China. In addition, we selectively present the traffic pattern of different applications in detail.展开更多
This paper presents a simple novel technique-forward gated-diode R-G current method-to determine the lateral lightly-doped source/drain (S/D) region interface state density and effective surface doping concentration o...This paper presents a simple novel technique-forward gated-diode R-G current method-to determine the lateral lightly-doped source/drain (S/D) region interface state density and effective surface doping concentration of the lightly-doped drain (LDD) N- MOSFET's simultaneously. One interesting result of the numerical analysis is the direct characterization of the interface state density and characteristic gate voltage values corresponding to LDD effective surface doping concentration. It is observed that the S/D N- surface doping concentration and corresponding region's interface state density are R-G current peak position and amplitude dependent, respectively. It is convincible that the proposed method is well suitable for the characterization of deep sub-micron MOSFET's in the current ULSI technology.展开更多
In this paper,the HRTEM lattice fringe micrograph of Caocun No.2 coal was extracted by ArcGIS,the length and orientation of the fringes were calculated,and the rose diagram for the lattice fringe micrograph was drawn ...In this paper,the HRTEM lattice fringe micrograph of Caocun No.2 coal was extracted by ArcGIS,the length and orientation of the fringes were calculated,and the rose diagram for the lattice fringe micrograph was drawn by Matlab.By controlling the segmentation points of each lattice fringe,the coordinates of the segmentation points were processed by a self-programmed Python program,and then a series of curvature characterizations including segmentation angle,cumulative angle and tortuosity were performed for lattice fringes with different lengths.The results show that Caocun No.2 coal is mainly composed of short naphthalene fringes.Lattice fringes with the length ranging from 0.3 nm to 1.14 nm account for more than 90%of the total number of fringes,and the number of polynuclear aromatic rings was 2-4.The direction of lattice fringes is concentrated between 110°and 120°,which indicates well structural orientation of lattice fringes.The number of segment angles ranging from 0°to 20°account for about half of the total,which reflects the structural orientation further.For fringes with the length ranging from 0.3 nm to 1.14 nm,the cumulative angles are mainly concentrated at 4°to 160°.Fringes with the tortuosity in the range of 1.0-1.1 are more than 92%of the total number of fringes.In addition,short fringes have large curvature,which shows significant effects on the placement and frequency of non-six-membered rings and lattice imperfection in the aromatic structure.展开更多
Characterizing spatial distribution of soil liquefaction potential is critical for assessing liquefactionrelated hazards(e.g.building damages caused by liquefaction-induced differential settlement).However,in engineer...Characterizing spatial distribution of soil liquefaction potential is critical for assessing liquefactionrelated hazards(e.g.building damages caused by liquefaction-induced differential settlement).However,in engineering practice,soil liquefaction potential is usually measured at limited locations in a specific site using in situ tests,e.g.cone penetration tests(CPTs),due to the restrictions of time,cost and access to subsurface space.In these cases,liquefaction potential of soil at untested locations requires to be interpreted from limited measured data points using proper interpolation method,leading to remarkable statistical uncertainty in liquefaction assessment.This underlines an important question of how to optimize the locations of CPT soundings and determine the minimum number of CPTs for achieving a target reliability level of liquefaction assessment.To tackle this issue,this study proposes a smart sampling strategy for determining the minimum number of CPTs and their optimal locations in a selfadaptive and data-driven manner.The proposed sampling strategy leverages on information entropy and Bayesian compressive sampling(BCS).Both simulated and real CPT data are used to demonstrate the proposed method.Illustrative examples indicate that the proposed method can adaptively and sequentially select the required number and optimal locations of CPTs.展开更多
In this paper, a kind of three-dimensional analysis technology for characterizing non-metallic inclusions in steel was clearly elaborated. It is an electron microscopy observation, namely the non-aqueous electrolysis ...In this paper, a kind of three-dimensional analysis technology for characterizing non-metallic inclusions in steel was clearly elaborated. It is an electron microscopy observation, namely the non-aqueous electrolysis extraction method with a settled coulometer. In the research,the extraction effects of non-metallic inclusions in different electrolysis systems were studied, and it was concluded that alkalescent 2% TEA non-aqueous electrolyte was applicable for extracting most of non-metallic inclusion particles in steel. And then, in order to ensure the microscopic characterization and statistical calculation of inclusion particles, some electrolysis parameters should be confirmed, such as the size of the sample, control of the electrolysis mass, electric current, etc. Furthermore, for preventing the disturbance of carbides and presenting clear three-dimensional appearance by microscopic characterization, magnetic separation was utilized to separate the inclusion particles from carbides, which was useful for getting more veracious types, particle sizes and chemical composition of inclusions. Moreover, through calculation of quantity and particle size of inclusions in continuous determinate fields, the total quantity per unit volume or area and the particle size distribution of inclusions could be acquired by conversion with electrolysis loss. Besides, the comparison between this method and traditional quantitative metallography was also discussed, and finally, a conclusion was drawn that both of them have respectively applications in characterizing inclusions.展开更多
Flow of fluids within biological tissues often meets with resistance that causes a rate-and size-dependent material behavior known as poroelasticity.Characterizing poroelasticity can provide insight into a broad range...Flow of fluids within biological tissues often meets with resistance that causes a rate-and size-dependent material behavior known as poroelasticity.Characterizing poroelasticity can provide insight into a broad range of physiological functions,and is done qualitatively in the clinic by palpation.Indentation has been widely used for characterizing poroelasticity of soft materials,where quantitative interpretation of indentation requires a model of the underlying physics,and such existingmodels are well established for cases of small strain and modest force relaxationWe showed here that existing models are inadequate for large relaxation,where the force on the indenter at a prescribed depth at long-time scale drops to below half of the initially peak force.We developed an indentation theory for such cases of large relaxation,based upon Biot theory and a generalized Hertz contact model.We demonstrated that proposed theory is suitable for biological tissues(e.g.,spleen,kidney,skin and human cirrhosis liver)with both small and large relaxations.The proposed method would be a powerful tool to characterize poroelastic properties of biological materials for various applications such as pathological study and disease diagnosis.展开更多
This study aimed to characterize constituents of phosphorus （P） fractionation as wel as reciprocities among factors in sediments of a freshwater shal ow lake. [Method] Surface sediment was discretely sampled at 24 s...This study aimed to characterize constituents of phosphorus （P） fractionation as wel as reciprocities among factors in sediments of a freshwater shal ow lake. [Method] Surface sediment was discretely sampled at 24 sites through Van Veen grabs. Based on a modified sequential extraction scheme, P fractionation was determined as Fe/Al bound P （Fe/Al-P）, Ca bound P （Ca-P）, solute and re-ductive P （S/R-P） and organic P （OP）. Curve estimation and Pearson product-mo-ment correlation were employed for statistical analysis. [Result] Total P （TP） content ranged from 443 to 774 mg/kg. Inorganic P （IP） was the major component of TP, of which Ca-P was dominated with an average of 51%±9.7%. Average contents of P fractionation were in the fol owing order： Ca-P（51%） 〉 OP（29%） 〉 S/R-P（8%） 〉Fe/Al-P（7%）. The molar ratio of Fe to P was 11 - 20, close to the threshold value of P leaching. [Conclusion] In freshwater shal ow lakes, IP and Ca-P were prone to be relatively high, whereas Fe/Al-P was low compared with deep lakes. Occurrence of spatial y monotonic gradient indicated the primary causation of anthropogenic sources. Imminent sediment P liberation was also expected. Close associations a-mong TP, Fe/Al-P and Ca-P, implying that anthropogenic P was mainly bound to metals in particulates. Significant correlations of TOC and P fractionation highlighted endogenous mechanism and authigenic origin in sediments.展开更多
With high computational capacity, e.g. many-core and wide floating point SIMD units, Intel Xeon Phi shows promising prospect to accelerate high-performance computing(HPC) applications. But the application of Intel Xeo...With high computational capacity, e.g. many-core and wide floating point SIMD units, Intel Xeon Phi shows promising prospect to accelerate high-performance computing(HPC) applications. But the application of Intel Xeon Phi on data analytics workloads in data center is still an open question. Phibench 2.0 is built for the latest generation of Intel Xeon Phi(KNL, Knights Landing), based on the prior work PhiBench(also named BigDataBench-Phi), which is designed for the former generation of Intel Xeon Phi(KNC, Knights Corner). Workloads of PhiBench 2.0 are delicately chosen based on BigdataBench 4.0 and PhiBench 1.0. Other than that, these workloads are well optimized on KNL, and run on real-world datasets to evaluate their performance and scalability. Further, the microarchitecture-level characteristics including CPI, cache behavior, vectorization intensity, and branch prediction efficiency are analyzed and the impact of affinity and scheduling policy on performance are investigated. It is believed that the observations would help other researchers working on Intel Xeon Phi and data analytics workloads.展开更多
Missouri is a state with rich karst terrain. Geotechnical evaluation of foundation design for bridges and dams requires an understanding of the characteristics of subsurface geological environment, including sediments...Missouri is a state with rich karst terrain. Geotechnical evaluation of foundation design for bridges and dams requires an understanding of the characteristics of subsurface geological environment, including sediments, bedrock and benthic habitat. It is crucial that the community empowers itself with the knowledge of the karst system’s characteristics in order to potentially use it as a source of water and drainage, but also to avoid the disaster of building constructions too close to vulnerable land on top of massive karst caverns. Electrical resistivity tomography profiling (underwater cables), and continuous resistivity profiling (towed cable) surveys were conducted to characterize the lake sediments (rock and soil) beneath the man-made Little Prairie Lake, in Central of Missouri State, United States. Electrical resistivity (with marine cables and towed cable) was used to determine variability in the lithology and thickness of sediments (soil and rock) beneath the lake with conjunction of echo sounder in order to calculate water depth. Side scan sonar was used to map the variations in the lithology/nature of exposed lakebed sediments and to locate the potential hazard of trees. On land, electrical resistivity tomography was used with multi-channel analysis of surface wave method to determine sediments, joints, and the depth of bedrock. Analyses of the acquired data revealed the location and orientation of the original stream channels (prior to the construction of the earth fill dam). Underwater electrical resistivity tomography and continuous resistivity profiling determined joints, sediments, and bedrock underneath water bodies. Integrated marine geophysical tools help to evaluate the subsurface prior to any construction project (dam or bridge), are useful in determining the characteristics of lithology (fractured rock, intact rock and soil), and make it possible to map benthic habitat and the submerged potential hazards of trees on the lakebed as well as accurately measuring water depth.展开更多
Big data analytics is emerging as one kind of the most important workloads in modern data centers. Hence,it is of great interest to identify the method of achieving the best performance for big data analytics workload...Big data analytics is emerging as one kind of the most important workloads in modern data centers. Hence,it is of great interest to identify the method of achieving the best performance for big data analytics workloads running on state-of-the-art SMT( simultaneous multithreading) processors,which needs comprehensive understanding to workload characteristics. This paper chooses the Spark workloads as the representative big data analytics workloads and performs comprehensive measurements on the POWER8 platform,which supports a wide range of multithreading. The research finds that the thread assignment policy and cache contention have significant impacts on application performance. In order to identify the potential optimization method from the experiment results,this study performs micro-architecture level characterizations by means of hardware performance counters and gives implications accordingly.展开更多
基金funded by the National Natural Science Foundation of China(Grant Nos.:81803812,81803237).
文摘Extracellular polymeric substances(EPS)constitutes crucial elements within bacterial biofilms,facili-tating accelerated antimicrobial resistance and conferring defense against the host's immune cells.Developing precise and effective antibiofilm approaches and strategies,tailored to the specific charac-teristics of EPS composition,can offer valuable insights for the creation of novel antimicrobial drugs.This,in turn,holds the potential to mitigate the alarming issue of bacterial drug resistance.Current analysis of EPS compositions relies heavily on colorimetric approaches with a significant bias,which is likely due to the selection of a standard compound and the cross-interference of various EPS compounds.Considering the pivotal role of EPS in biofilm functionality,it is imperative for EPS research to delve deeper into the analysis of intricate compositions,moving beyond the current focus on polymeric materials.This ne-cessitates a shift from heavy reliance on colorimetric analytic methods to more comprehensive and nuanced analytical approaches.In this study,we have provided a comprehensive summary of existing analytical methods utilized in the characterization of EPS compositions.Additionally,novel strategies aimed at targeting EPS to enhance biofilm penetration were explored,with a specific focus on high-lighting the limitations associated with colorimetric methods.Furthermore,we have outlined the challenges faced in identifying additional components of EPS and propose a prospective research plan to address these challenges.This review has the potential to guide future researchers in the search for novel compounds capable of suppressing EPS,thereby inhibiting biofilm formation.This insight opens up a new avenue for exploration within this research domain.
基金supported by the National Key Research and Development Program of China under the sub-theme“Research on the Path of Enhancing the Sustainable Development Capacity of Cities and Towns under the Carbon Neutral Goal”[Grant No.2022YFC3802902-04].
文摘In response to the United Nations Sustainable Development Goals and China’s“Dual Carbon”Goals(DCGs means the goals of“Carbon Peak and carbon neutrality”),this paper from the perspective of the construction of China’s Innovation Demonstration Zones for Sustainable Development Agenda(IDZSDAs),combines carbon emission-related metrics to construct a comprehensive assessment system for Urban Sustainable Development Capacity(USDC).After obtaining USDC assessment results through the assessment system,an approach combining Least Absolute Shrinkage and Selection Operator(LASSO)regression and Random Forest(RF)based on machine learning is proposed for identifying influencing factors and characterizing key issues.Combining Coupling Coordination Degree(CCD)analysis,the study further summarizes the systemic patterns and future directions of urban sustainable development.A case study on the IDZSDAs from 2015 to 2022 reveals that:(1)the combined identification method based on machine learning and CCD models effectively quantifies influencing factors and key issues in the urban sustainable development process;(2)the correspondence between influencing factors and key subsystems identified by the LASSO-RF combination model is generally consistent with the development situations in various cities;and(3)the machine learning-based combined recognition method is scalable and dynamic.It enables decision-makers to accurately identify influencing factors and characterize key issues based on actual urban development needs.
基金supported by the National Natural Science Foundation of China (31570155 and 31370199)"Young Top-notch Talents" of the Guangdong Province Special Support Program (2014)+3 种基金the Excellent Young Teacher Training Plan of Guangdong Province (Yq2013039)the Guangzhou Healthcare Collaborative Innovation Major Project (201400000002)funded by the China Scholarship Council (CSC No. 201508440056) as a Visiting Scholar (2015-2016)supported by a summer research grant to D.S. from the Office of the Vice President for Research at George Mason University
文摘Restriction endonuclease analysis(REA),or restriction fragment length polymorphism(RFLP),was useful for identifying and determining the relatedness and putative identities of microbial strains(Tang et al.,1997)and for characterizing and discriminating large numbers of samples inexpensively in the past。
基金Projects(50471102,50671089) supported by the National Natural Science Foundation of China
文摘In order to establish the quantitative relationship between equivalent strain and the performance index of the deformed material within the range of certain passes for equal channel angular processing （ECAP）, a new approach to characterize the equivalent strain was proposed. The results show that there exists better accordance between mechanical property （such as hardness or strength） and equivalent strain after rolling and ECAP in a certain range of deformation amount, and Gauss equation can be satisfied among the equivalent strain and the mechanical properties for ECAP. Through regression analysis on the data of hardness and strength after the deformation, a more generalized expression of equivalent strain for ECAP is proposed as：ε=k0exp[-（k1M-k2）^2], where M is the strength or hardness of the material, k1 is the modified coefficient （k1∈ （0, 1））, ko and k2 are two parameters dependent on the critical strain and mechanical property that reaches saturation state for the material, respectively. In this expression the equivalent strain for ECAP is characterized novelly through the mechanical parameter relating to material property rather than the classical geometry equation.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61574019,61674018 and 61674020the Fund of State Key Laboratory of Information Photonics and Optical Communicationsthe Specialized Research Fund for the Doctoral Program of Higher Education of China under Grant No 20130005130001
文摘Two measurement techniques are investigated to characterize photodetector linearity. A model for the two-tone and three-tone photodetector systems is developed to thoroughly investigate the influences of setup components on the measurement results. We demonstrate that small bias shifts from the quadrature point of the modulator will induce deviation into measurement results of the two-tone system, and the simulation results correspond well to experimental and calculation results.
文摘An enhanced small-signal model is introduced to model the influence of the impact ionization effect on the performance of In As/Al Sb HFET, in which an optimized fitting function D（ωτi） in the form of least square approximation is proposed in order to further enhance the accuracy in modeling the frequency dependency of the impact ionization effect.The enhanced model with D（ωτi） can accurately characterize the key S parameters of In As/Al Sb HFET in a wide frequency range with a very low error function EF. It is demonstrated that the new fitting function D（ωτi） is helpful in further improving the modeling accuracy degree.
文摘Surface-enhanced Raman Spectroscopy(SERS)has been used to characterize hurnic substances.By using HNO_3 -roughened silver foils as the enhancing surface,both fluorescence quenching and strong SERS signals have been observed at the same time.The results obtained herein show that SERS is a particularly sensitive and highly selective technique for the characterization of humic substances in the environment. Humic substances axe receiving ever-inereasing attention because of their importance in the environment. Very recently,we have reported the first successful application of Raman spectroscopy for characterizing humic substances.In this present paper,the application of surface-enhanced Raman spectroscopy(SERS)for humic substances has further been investigated.To our knowledge,no such studies have previously been reported.The results obtained herein dearly demonstrate that SERS has a great deal of promise as an analytical method for“In Situ”characterizing humic substances in the environment.
基金supported by the Chinese National Major Fundamental Research Developing Project(No.2011ZX08005-004)the National Natural Science Foundation of China(No.41102078)
文摘The occurrence of hydrocarbon migration in petroliferous basins depends on the balance of driving force and resistance of carriers, which restricts mostly the quantity and positions of hydrocarbon accumulation. The driving forces of hydrocarbon migration have been quantitatively studied, whereas the migration pathways and carriers were only qualitatively discussed up to now. Establishing a compound hydrocarbon carrier system and quantitatively characterizing its transport capability are significant for understanding the dynamic process of hydrocarbon migration and revealing the hydrocarbon accumulation characteristics. It has become an innovatory trend and also a difficult topic in study of hydrocarbon migration. In this article, a method is described for using displacement pressure to quantitatively characterize the transport capability of the compound carrier system, which composed of sandstone carriers, unconformities and faults. When the weathered and leached zone rarely developed, the basal conglomerate or transgressive sandstone of unconformities can be treated as part of sandstone carriers. An empirical relationship among core porosity, air permeability, and the pore aperture radius corresponding to a mercury saturation of 10% （r 10 ） can be obtained by multiple regression. Using porosity and permeability inversed by seismic data, the displacement pressure of sandstone carriers can be calculated by the empirical relationship and Washburn Equation. Displacement pressure of fault plane can be estimated by the regression formula between fault opening index （FOI） and hydrocarbon column height it can support. This method is applied in the eastern part of south slope in Dongying （东营） depression, Bohai （渤海） Bay Basin, China, to quantitatively characterize thetransport capability of the compound carrier system of Shahejie （沙河街） Formation. The results have good agreement with data from drilling wells. This method may be a step further in study of compound hydrocarbon carrier system in petroliferous basins. It may provide the basis of coupling expulsion quantity, migration driving force and hydrocarbon carrier system to simulate hydrocarbon migration and accumulation. Therefore this will help predict hydrocarbon migration pathways and the locations ofhydrocarbon accumulation.
基金This paper was partially supported by the National Natural Science Foundation of China under Crant No. 61072061111 Project of China under Crant No. B08004 the Fundamental Research Funds for the Central Universities under Grant No. 2009RC0122. References
文摘Based on the massive data collected with a passive network monitoring equipment placed in China＇s backbone, we present a deep insight into the network backbone traffic and evaluate various ways for inproving traffic classifying efficiency in this pa- per. In particular, the study has scrutinized the net- work traffic in terms of protocol types and signatures, flow length, and port distffoution, from which mean- ingful and interesting insights on the current Intemet of China from the perspective of both the packet and flow levels are derived. We show that the classifica- tion efficiency can be greatly irrproved by using the information of preferred ports of the network applica- tions. Quantitatively, we find two traffic duration thresholds, with which 40% of TCP flows and 70% of UDP flows can be excluded from classification pro- cessing while the in^act on classification accuracy is trivial, i.e., the classification accuracy can still reach a high level by saving 85% of the resources.
基金This study was funded by the Natural Science Foundation of Shanghai“Scientific and Technological Innovation Action Plan”(20ZR1444600)as well as the Special Fund for Scientific and Technological Innovation of Shanghai Jiao Tong University(YG2019ZDA27。
文摘Contrast-enhanced ultrasound(CEUS)is a new form of ultrasound(US)that can dynamically display microvessels in a highly sensitive manner.The purpose of this study was to investigate the efficacy of CEUS for characterizing testicular lesions in comparison with conventional US.Forty-seven patients with testicular lesions were enrolled.The histopathology results revealed that 31 cases were neoplastic(11 cases of seminomas,8 nonseminomatous germ cell tumors,8 lymphomas,2 Leydig cell tumors,and 2 nonspecific tumors),and 16 cases were nonneoplastic(8 cases of infarctions,3 epidermoid cysts,and 5 inflammation).The indicators of shallow lobulated morphology and cystic-solid echogenicity on conventional US were suggestive of germ cell tumors.More indicators on CEUS were found to be useful for characterizing testicular lesions.All the neoplastic lesions showed hyperenhancement on CEUS.Moreover,germ cell tumors presented with heterogeneous enhancement(73.7%,14/19),a twisted blood vessel pattern,rapid wash-in and wash-out,and peripheral rim hyperenhancement signs.Lymphoma was characterized by nonbranching linear vessel patterns(87.5%,7/8),rapid wash-in and slow wash-out.In nonneoplastic lesions,infarction and epidermoid cysts showed no enhancement,and abscesses were observed with marginal irregular enhancement.The sensitivity,specificity,and accuracy of CEUS for differentiating between neoplastic and nonneoplastic lesions were 100%,93.8%,and 97.9%,respectively,and these values were higher than those for conventional US(90.3%,62.5%,and 80.9%,respectively).CEUS can sensitively reflect the microvascular perfusion in testicular lesions and offers high accuracy for characterizing them.
文摘With enormous growth of the number of Internet users and appearance of new applications, characterization of Internet traffic has attracted more and more attention and has become one of the major challenging issues in telecommunication network over the past few years. In this paper, we study the network traffic pattern of the aggregate traffic and of specific application traffic, especially the popular applications such as P2P, VoIP that contribute most network traffic. Our study verified that majority Internet backbone traffic is contributed by a small portion of users and a power function can be used to approximate the contribution of each user to the overall traffic. We show that P2P applications are the dominant traffic contributor in current Internet Backbone of China. In addition, we selectively present the traffic pattern of different applications in detail.
基金Sponsored by Motorola CPTL(Contract No:MSPSDDLCHINA-0004)
文摘This paper presents a simple novel technique-forward gated-diode R-G current method-to determine the lateral lightly-doped source/drain (S/D) region interface state density and effective surface doping concentration of the lightly-doped drain (LDD) N- MOSFET's simultaneously. One interesting result of the numerical analysis is the direct characterization of the interface state density and characteristic gate voltage values corresponding to LDD effective surface doping concentration. It is observed that the S/D N- surface doping concentration and corresponding region's interface state density are R-G current peak position and amplitude dependent, respectively. It is convincible that the proposed method is well suitable for the characterization of deep sub-micron MOSFET's in the current ULSI technology.
基金Supported by the National Natural Science Foundation of China(41602177,41802191,41702175)
文摘In this paper,the HRTEM lattice fringe micrograph of Caocun No.2 coal was extracted by ArcGIS,the length and orientation of the fringes were calculated,and the rose diagram for the lattice fringe micrograph was drawn by Matlab.By controlling the segmentation points of each lattice fringe,the coordinates of the segmentation points were processed by a self-programmed Python program,and then a series of curvature characterizations including segmentation angle,cumulative angle and tortuosity were performed for lattice fringes with different lengths.The results show that Caocun No.2 coal is mainly composed of short naphthalene fringes.Lattice fringes with the length ranging from 0.3 nm to 1.14 nm account for more than 90%of the total number of fringes,and the number of polynuclear aromatic rings was 2-4.The direction of lattice fringes is concentrated between 110°and 120°,which indicates well structural orientation of lattice fringes.The number of segment angles ranging from 0°to 20°account for about half of the total,which reflects the structural orientation further.For fringes with the length ranging from 0.3 nm to 1.14 nm,the cumulative angles are mainly concentrated at 4°to 160°.Fringes with the tortuosity in the range of 1.0-1.1 are more than 92%of the total number of fringes.In addition,short fringes have large curvature,which shows significant effects on the placement and frequency of non-six-membered rings and lattice imperfection in the aromatic structure.
基金supported by grants from the Research Grant Council of Hong Kong Special Administrative Region,China(Project Nos.CityU 11202121 and CityU 11213119).
文摘Characterizing spatial distribution of soil liquefaction potential is critical for assessing liquefactionrelated hazards(e.g.building damages caused by liquefaction-induced differential settlement).However,in engineering practice,soil liquefaction potential is usually measured at limited locations in a specific site using in situ tests,e.g.cone penetration tests(CPTs),due to the restrictions of time,cost and access to subsurface space.In these cases,liquefaction potential of soil at untested locations requires to be interpreted from limited measured data points using proper interpolation method,leading to remarkable statistical uncertainty in liquefaction assessment.This underlines an important question of how to optimize the locations of CPT soundings and determine the minimum number of CPTs for achieving a target reliability level of liquefaction assessment.To tackle this issue,this study proposes a smart sampling strategy for determining the minimum number of CPTs and their optimal locations in a selfadaptive and data-driven manner.The proposed sampling strategy leverages on information entropy and Bayesian compressive sampling(BCS).Both simulated and real CPT data are used to demonstrate the proposed method.Illustrative examples indicate that the proposed method can adaptively and sequentially select the required number and optimal locations of CPTs.
文摘In this paper, a kind of three-dimensional analysis technology for characterizing non-metallic inclusions in steel was clearly elaborated. It is an electron microscopy observation, namely the non-aqueous electrolysis extraction method with a settled coulometer. In the research,the extraction effects of non-metallic inclusions in different electrolysis systems were studied, and it was concluded that alkalescent 2% TEA non-aqueous electrolyte was applicable for extracting most of non-metallic inclusion particles in steel. And then, in order to ensure the microscopic characterization and statistical calculation of inclusion particles, some electrolysis parameters should be confirmed, such as the size of the sample, control of the electrolysis mass, electric current, etc. Furthermore, for preventing the disturbance of carbides and presenting clear three-dimensional appearance by microscopic characterization, magnetic separation was utilized to separate the inclusion particles from carbides, which was useful for getting more veracious types, particle sizes and chemical composition of inclusions. Moreover, through calculation of quantity and particle size of inclusions in continuous determinate fields, the total quantity per unit volume or area and the particle size distribution of inclusions could be acquired by conversion with electrolysis loss. Besides, the comparison between this method and traditional quantitative metallography was also discussed, and finally, a conclusion was drawn that both of them have respectively applications in characterizing inclusions.
文摘Flow of fluids within biological tissues often meets with resistance that causes a rate-and size-dependent material behavior known as poroelasticity.Characterizing poroelasticity can provide insight into a broad range of physiological functions,and is done qualitatively in the clinic by palpation.Indentation has been widely used for characterizing poroelasticity of soft materials,where quantitative interpretation of indentation requires a model of the underlying physics,and such existingmodels are well established for cases of small strain and modest force relaxationWe showed here that existing models are inadequate for large relaxation,where the force on the indenter at a prescribed depth at long-time scale drops to below half of the initially peak force.We developed an indentation theory for such cases of large relaxation,based upon Biot theory and a generalized Hertz contact model.We demonstrated that proposed theory is suitable for biological tissues(e.g.,spleen,kidney,skin and human cirrhosis liver)with both small and large relaxations.The proposed method would be a powerful tool to characterize poroelastic properties of biological materials for various applications such as pathological study and disease diagnosis.
基金Supported by the National Natural Science Foundation of China(grant No.41171384,41271414 and 41301529)
文摘This study aimed to characterize constituents of phosphorus （P） fractionation as wel as reciprocities among factors in sediments of a freshwater shal ow lake. [Method] Surface sediment was discretely sampled at 24 sites through Van Veen grabs. Based on a modified sequential extraction scheme, P fractionation was determined as Fe/Al bound P （Fe/Al-P）, Ca bound P （Ca-P）, solute and re-ductive P （S/R-P） and organic P （OP）. Curve estimation and Pearson product-mo-ment correlation were employed for statistical analysis. [Result] Total P （TP） content ranged from 443 to 774 mg/kg. Inorganic P （IP） was the major component of TP, of which Ca-P was dominated with an average of 51%±9.7%. Average contents of P fractionation were in the fol owing order： Ca-P（51%） 〉 OP（29%） 〉 S/R-P（8%） 〉Fe/Al-P（7%）. The molar ratio of Fe to P was 11 - 20, close to the threshold value of P leaching. [Conclusion] In freshwater shal ow lakes, IP and Ca-P were prone to be relatively high, whereas Fe/Al-P was low compared with deep lakes. Occurrence of spatial y monotonic gradient indicated the primary causation of anthropogenic sources. Imminent sediment P liberation was also expected. Close associations a-mong TP, Fe/Al-P and Ca-P, implying that anthropogenic P was mainly bound to metals in particulates. Significant correlations of TOC and P fractionation highlighted endogenous mechanism and authigenic origin in sediments.
基金Supported by the National High Technology Research and Development Program of China(No.2015AA015308)the National Key Research and Development Plan of China(No.2016YFB1000600,2016YFB1000601)the Major Program of National Natural Science Foundation of China(No.61432006)
文摘With high computational capacity, e.g. many-core and wide floating point SIMD units, Intel Xeon Phi shows promising prospect to accelerate high-performance computing(HPC) applications. But the application of Intel Xeon Phi on data analytics workloads in data center is still an open question. Phibench 2.0 is built for the latest generation of Intel Xeon Phi(KNL, Knights Landing), based on the prior work PhiBench(also named BigDataBench-Phi), which is designed for the former generation of Intel Xeon Phi(KNC, Knights Corner). Workloads of PhiBench 2.0 are delicately chosen based on BigdataBench 4.0 and PhiBench 1.0. Other than that, these workloads are well optimized on KNL, and run on real-world datasets to evaluate their performance and scalability. Further, the microarchitecture-level characteristics including CPI, cache behavior, vectorization intensity, and branch prediction efficiency are analyzed and the impact of affinity and scheduling policy on performance are investigated. It is believed that the observations would help other researchers working on Intel Xeon Phi and data analytics workloads.
文摘Missouri is a state with rich karst terrain. Geotechnical evaluation of foundation design for bridges and dams requires an understanding of the characteristics of subsurface geological environment, including sediments, bedrock and benthic habitat. It is crucial that the community empowers itself with the knowledge of the karst system’s characteristics in order to potentially use it as a source of water and drainage, but also to avoid the disaster of building constructions too close to vulnerable land on top of massive karst caverns. Electrical resistivity tomography profiling (underwater cables), and continuous resistivity profiling (towed cable) surveys were conducted to characterize the lake sediments (rock and soil) beneath the man-made Little Prairie Lake, in Central of Missouri State, United States. Electrical resistivity (with marine cables and towed cable) was used to determine variability in the lithology and thickness of sediments (soil and rock) beneath the lake with conjunction of echo sounder in order to calculate water depth. Side scan sonar was used to map the variations in the lithology/nature of exposed lakebed sediments and to locate the potential hazard of trees. On land, electrical resistivity tomography was used with multi-channel analysis of surface wave method to determine sediments, joints, and the depth of bedrock. Analyses of the acquired data revealed the location and orientation of the original stream channels (prior to the construction of the earth fill dam). Underwater electrical resistivity tomography and continuous resistivity profiling determined joints, sediments, and bedrock underneath water bodies. Integrated marine geophysical tools help to evaluate the subsurface prior to any construction project (dam or bridge), are useful in determining the characteristics of lithology (fractured rock, intact rock and soil), and make it possible to map benthic habitat and the submerged potential hazards of trees on the lakebed as well as accurately measuring water depth.
基金Supported by the National High Technology Research and Development Program of China(No.2015AA015308)the State Key Development Program for Basic Research of China(No.2014CB340402)
文摘Big data analytics is emerging as one kind of the most important workloads in modern data centers. Hence,it is of great interest to identify the method of achieving the best performance for big data analytics workloads running on state-of-the-art SMT( simultaneous multithreading) processors,which needs comprehensive understanding to workload characteristics. This paper chooses the Spark workloads as the representative big data analytics workloads and performs comprehensive measurements on the POWER8 platform,which supports a wide range of multithreading. The research finds that the thread assignment policy and cache contention have significant impacts on application performance. In order to identify the potential optimization method from the experiment results,this study performs micro-architecture level characterizations by means of hardware performance counters and gives implications accordingly.
