Channelization typically realized by digital filter banks is an important topic in high frequency(HF) communication and software defined radios(SDR) areas. Channelization has a rigorous requirement for the characteris...Channelization typically realized by digital filter banks is an important topic in high frequency(HF) communication and software defined radios(SDR) areas. Channelization has a rigorous requirement for the characteristic of frequency response, e.g., steep transitional band and sharp decay. To address this issue, we investigated the feasibility and implementation of applying fast filter bank(FFB) in channelization in this paper. We analyzed the butterfly structure of FFB similar with fast Fourier transform(FFT), in which prototype sub-filters are cascaded to achieve a low complexity. Hence, it is suitable for designing filter bank with steep transitional band and sharp decay in stop-band. Moreover, we designed a pipelined structure of FFB to achieve a balance between area and performance. Design example shows that FFB has lower computational complexity compared with the other filter banks.展开更多
A multistandard software-defined radio base station must perform non-uniform channelization of multiplexed frequency bands. Non-uniform channelization accounts for a significant portion of the digital signal processin...A multistandard software-defined radio base station must perform non-uniform channelization of multiplexed frequency bands. Non-uniform channelization accounts for a significant portion of the digital signal processing workload in the base station receiver and can be difficult to realize in a physical implementation. In non-uniform channelization methods based on generalized DFT filter banks, large prototype filter orders are a significant issue for implementation. In this paper, a multistage filter design is applied to two different non-uniform generalized DFT-based channelizers in order to reduce their filter orders. To evaluate the approach, a TETRA and TEDS base station is used. Experimental results show that the new multistage design reduces both the number of coefficients and operations and leads to a more feasible design and practical physical implementation.展开更多
Channel straightening in a naturally meandering river is a common historical trigger of channel incision which typically results in stream bank destabilization. Several of the larger river systems in the upland portio...Channel straightening in a naturally meandering river is a common historical trigger of channel incision which typically results in stream bank destabilization. Several of the larger river systems in the upland portion of the Yazoo River Basin have subjected channelization resulting in profound changes in the physical and geomorphological characteristics of these systems. Fish were sampled using electroshocking gear and hoop nets to evaluate the impact of stream bank destabilization and loss of habitat heterogeneity resulting from channelization on fish communities. While distinct differences in the fish communities were evident, only the Skuna appeared to have characteristics of a damaged system. More than 95% of the biomass was comprised of species reaching an adult length of less than 300 mm. The lotic omnivorous fishes that dominated the biomass from Skuna are often associated with smaller streams rather than rivers. Furthermore, 72% of the catch consisted of fish preferring littoral zone habitats. The shallow depth and lack of woody debris in Skuna provided a selective advantage for smaller species of fish that could use shoreline habitats as protection from the current. Based on results from the Skuna River, channel straightening that leads to channel incision, bank failure and over widening provide habitats too shallow to support a community of fishes typical of northern Mississippi riverine system. This information may be useful in making comparison of damaged riverine ecosystems and assist managers in determining impairment and success in the TMDL (Total Maximum Daily Load) process.展开更多
Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,...Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,and necroptosis.Oligomerization of mitochondrial voltage-dependent anion channel 1 is an important pathological event in regulating cell death in retinal ischemia–reperfusion injury.However,its role in PANoptosis remains largely unknown.In this study,we demonstrated that voltage-dependent anion channel 1 oligomerization-mediated mitochondrial dysfunction was associated with PANoptosis in retinal ischemia–reperfusion injury.Inhibition of voltage-dependent anion channel 1 oligomerization suppressed mitochondrial dysfunction and PANoptosis in retinal cells subjected to ischemia–reperfusion injury.Mechanistically,mitochondria-derived reactive oxygen species played a central role in the voltagedependent anion channel 1-mediated regulation of PANoptosis by promoting PANoptosome assembly.Moreover,inhibiting voltage-dependent anion channel 1 oligomerization protected against PANoptosis in the retinas of rats subjected to ischemia–reperfusion injury.Overall,our findings reveal the critical role of voltage-dependent anion channel 1 oligomerization in regulating PANoptosis in retinal ischemia–reperfusion injury,highlighting voltage-dependent anion channel 1 as a promising therapeutic target.展开更多
Lithium–sulfur(Li–S)batteries are promisingcandidates for next-generation energy storagegiven their high energy density and potential low cost.Chemically activated carbon(CAC)is often used fortheir cathodes,because ...Lithium–sulfur(Li–S)batteries are promisingcandidates for next-generation energy storagegiven their high energy density and potential low cost.Chemically activated carbon(CAC)is often used fortheir cathodes,because it has a high specific surfacearea for sulfur loading.We have developed a pressurizedphysical activation(PPA)method that producedan activated carbon(PPAC)with a high specific surfacearea comparable to that of CAC.The pore structure of PPAC could be changed and its use as a cathode material for Li–Sbatteries was investigated.Battery tests at different capacity rates(C-rates)showed that it had a much improved high-rate performancewith a discharge capacity of 900 mAh/(g of sulfur)at 1 C,in contrast to only 600 mAh/(g of sulfur)for CAC.Porestructure analyses showed that PPAC prepared at a high activation temperature(1000℃)had unusual channel-like mesoporesbetween the microdomains that are the basic structural units of artificial carbon materials.These are connected to microporesdeveloped in each microdomain,and deliver ions from the surroundings to the internal pores and vice versa.The well-developedmicropores and mesopores of PPAC respectively ensured the high adsorption of lithium polysulfides and a high rate ofion diffusion.Compared to CAC,PPAC is a high-performance,low-cost cathode material that is promising for use in futureLi–S batteries.展开更多
Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and dis...Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and disease,the search for new compounds that modulate these proteins is still relevant.Traditional medicine has long been a rich source of neuroactive compounds.For example,the indigenous Mapuche people have used the leaves and bark of the Drimys winteri tree for centuries to treat various diseases.Consequently,several studies have investigated the biological effects of compounds in Drimys winteri,highlighting sesquiterpenes such asα-humulene,drimenin,polygodial,andα-,β-,γ-eudesmol.However,there is currently no literature review focusing on the ability of these sesquiterpenes to modulate ion channels.This review summarizes the current knowledge about neuroactive compounds found in Drimys winteri,with special emphasis on their direct actions on neuronal ion channels.Several Drimys winteri sesquiterpenes modulate a diverse array of neuronal ion channels,including transient receptor potential channels,gamma-aminobutyric acid A receptors,nicotinic acetylcholine receptors,and voltage-dependent Ca^(2+)and Na^(+)channels.Interestingly,the modulation of these molecular targets by Drimys winteri sesquiterpenes correlates with their therapeutic actions.The promiscuous pharmacological profile of Drimys winteri sesquiterpenes suggests they modulate multiple protein targets in vivo,making them potentially useful for treating complex,multifactorial diseases.Further studies at the molecular level may aid in developing multitargeted drugs with enhanced therapeutic effects.展开更多
The smart meter communication system has substantial application value for the construction and upgrading of the entire power system.The deployment of the transmitter(Tx)of the smart meter system in the residential sc...The smart meter communication system has substantial application value for the construction and upgrading of the entire power system.The deployment of the transmitter(Tx)of the smart meter system in the residential scenarios is vexed by the need for more theoretical support.This paper mainly studies the communication channel between the Tx at semibasement and receiver(Rx)at outdoor.The design of an effective communication system relies on an accurate understanding of channel characteristics.Channel measurements and ray-tracing channel modeling are conducted to obtain channel data.The influence of different positions at same semi-basement is studied.Typical channel characteristics are analyzed,such as power delay profile(PDP),power angular profile(PAP),root-mean-square(RMS)delay spread(DS),channel capacity,received power,and path loss.The influence of different semi-basement placements and different floor heights is also compared.Besides,the channel measurements and simulation data fit well,which can illustrate the validity and reliability of the acquired channel data.This paper can provide theoretical support for the design and optimization of smart meter communication systems in semi-basement scenarios.展开更多
(Quasi-)closed-form results for the statistical properties of unmanned aerial vehicle(UAV)airto-ground channels are derived for the first time using a novel spatial-vector-based method from a threedimensional(3-D)arbi...(Quasi-)closed-form results for the statistical properties of unmanned aerial vehicle(UAV)airto-ground channels are derived for the first time using a novel spatial-vector-based method from a threedimensional(3-D)arbitrary-elevation one-cylinder model.The derived results include a closed-form expression for the space-time correlation function and some quasi-closed-form ones for the space-Doppler power spectrum density,the level crossing rate,and the average fading duration,which are shown to be the generalizations of those previously obtained from the two-dimensional(2-D)one-ring model and the 3-D low-elevation one-cylinder model for terrestrial mobile-to-mobile channels.The close agreements between the theoretical results and the simulations as well as the measurements validate the utility of the derived channel statistics.Based on the derived expressions,the impacts of some parameters on the channel characteristics are investigated in an effective,efficient,and explicable way,which leads to a general guideline on the manual parameter estimation from the measurement description.展开更多
A terrestrial relay-aided reconfigurable intelligent surface(RIS)system with decode,re-encode and forward(DRF)relaying scheme is presented where the RIS effectively contributes to both sourceto-destination and relay-t...A terrestrial relay-aided reconfigurable intelligent surface(RIS)system with decode,re-encode and forward(DRF)relaying scheme is presented where the RIS effectively contributes to both sourceto-destination and relay-to-destination signaling.While in the conventional decode and forward(DF)relaying scheme,the source signal is merely duplicated in the relay and the time intervals are equally allocated to the source and relay nodes,this paper considers DRF relaying scheme where versatile time-sharing is adopted for the source and relay nodes which can be optimized based on the relative coordinates of the involved nodes.Two protocols namely unidirectional connection(UC)and bidirectional connection(BC)are proposed based on the source awareness from the relay’s successful reception.The outage probability(OP)performance for both protocols and both DF and DRF relaying schemes is analyzed and tight approximations are obtained.The numerical results show the out-performance of the DRF over the DF relaying scheme in the both UC and BC protocols.Equipped with the obtained system OP,the system throughput is defined and the optimum system throughput is obtained by optimizing the system rate and the timesharing between the source and the relay.Analytical results are corroborated in the numerical examples.展开更多
The orthogonal time frequency space(OTFS)modulation is a novel modulation scheme that can effectively cope with the high Doppler expansion caused by high mobility.Since it modulates data on delay-Doppler(DD)domain and...The orthogonal time frequency space(OTFS)modulation is a novel modulation scheme that can effectively cope with the high Doppler expansion caused by high mobility.Since it modulates data on delay-Doppler(DD)domain and makes full use of the sparse characteristics of DD domain,it has been widely studied to design efficient channel estimation and signal detection schemes.In this paper,we design a novel superimposed pilot pattern with transition band,which replaces the traditional embedded pilot(EP)guard zero-symbols,and perform a two-stage channel estimation.In the first stage,we fully utilize the dispersion characteristics of OTFS signal in DD domain,and use threshold decision to make coarse channel estimation.In the second stage,we use the results of the coarse estimation for iterative signal detection and accurate channel estimation.During the second stage,we make full use of the sparsity of the channel in DD domain,remodel the received signal into the form of sparse channel vector multiplied by channel coefficient matrix,and introduce Doppler index segmentation factor(DISF)to subdivide the Doppler index to solve the problem of fractional Doppler.Simulations reveal that,the scheme proposed in this paper has higher spectral efficiency compared with traditional EP scheme and lower peak-to-average power ratio(PAPR)compared with traditional superimposed pilot scheme.展开更多
Osmotic energy,existing between the seawater and river water,is a renewable energy source,which can be directly converted into electricity by ion-exchange membranes(IEM).In traditional IEMs,the ion transport channels ...Osmotic energy,existing between the seawater and river water,is a renewable energy source,which can be directly converted into electricity by ion-exchange membranes(IEM).In traditional IEMs,the ion transport channels are formed by nanophase separation of hydrophilic ion carriers and hydrophobic segments.It is difficult to realize high-density ion channels with controlled spatial arrangement and length scale of ion carriers.Herein,we construct high-density 1D ion wires as transmission channels.Through molecular design,hydrophilic imidazole groups and hydrophobic alkyl tails were introduced into the repeat units,which self-assembled into 1D ion transporting core and protecting shell along the main chains.The areal density of the ionic wire arrays is up to~10^(12)cm^(-2),which is the highest value.The ionic wires ensure both high ion flux transport and high selectivity,achieving an ultrahigh-power density of 40.5 W m^(-2)at a 500-fold salinity gradient.Besides,the ionic wire array membrane is well recyclable and antibacterial.The ionic wires provide novel concept for next generation of high-performance membranes.展开更多
Reconfigurable intelligent surfaces(RISs)not only assist communication but also help the localization of user equipment(UE).This study focuses on indoor localization of UE with a single access point(AP)and multiple RI...Reconfigurable intelligent surfaces(RISs)not only assist communication but also help the localization of user equipment(UE).This study focuses on indoor localization of UE with a single access point(AP)and multiple RISs.First,we propose a two-stage channel estimation scheme where RIS phase shifts are tuned to obtain multiple channel soundings.In the first stage,the newtonized orthogonal matching pursuit algorithm extracts the parameters of multiple paths from the received signals.Then,the LOS path and RISreflected paths are identified.In the second stage,the estimated path gains of RIS-reflected paths with different phase shifts are utilized to determine the angle of arrival(AOA)at the RIS by obtaining the angular pseudo spectrum.Consequently,by taking the AP and RISs as reference points,the linear least squares estimator can locate UE with the estimated AOAs.Simulation results show that the proposed algorithm can realize centimeter-level localization accuracy in the discussed scenarios.Moreover,the higher accuracy of pseudo spectrum,a larger number of channel soundings,and a larger number of reference points can realize higher localization accuracy of UE.展开更多
Einstein–Podolsky–Rosen(EPR)steering is an important resource for one-sided device-independent quantum information processing.This steering property can be destroyed by the interaction between a quantum system and i...Einstein–Podolsky–Rosen(EPR)steering is an important resource for one-sided device-independent quantum information processing.This steering property can be destroyed by the interaction between a quantum system and its environment in practical applications.In this paper,we employ the characteristic function representation of probability distributions to investigate the quantum steering of two-mode continuous-variable states in a laser channel,where both the gain factor and the loss effect are taken into account.Firstly,we analyse the steering time of the two-mode squeezed vacuum state under one-mode and two-mode laser channels,respectively.We find that the gain process introduces additional noise into the two-mode squeezed vacuum state,thereby reducing the steerable time.Secondly,by quantifying EPR steering,we show that two-side loss exhibits smaller steerability than one-side loss,although they share the same two-way steerable time.In addition,we find that the more-gained party can steer the other party’s state,whereas the other party cannot steer the gained party beyond a certain threshold value.In this sense,the gain effect in one party appears to be equivalent to the loss effect in the other party.Our results pave the way for the distillation of EPR steering and quantum information processing in practical quantum channels.展开更多
Wi-Fi technology has evolved significantly since its introduction in 1997,advancing to Wi-Fi 6 as the latest standard,with Wi-Fi 7 currently under development.Despite these advancements,integrating machine learning in...Wi-Fi technology has evolved significantly since its introduction in 1997,advancing to Wi-Fi 6 as the latest standard,with Wi-Fi 7 currently under development.Despite these advancements,integrating machine learning into Wi-Fi networks remains challenging,especially in decentralized environments with multiple access points(mAPs).This paper is a short review that summarizes the potential applications of federated reinforcement learning(FRL)across eight key areas of Wi-Fi functionality,including channel access,link adaptation,beamforming,multi-user transmissions,channel bonding,multi-link operation,spatial reuse,and multi-basic servic set(multi-BSS)coordination.FRL is highlighted as a promising framework for enabling decentralized training and decision-making while preserving data privacy.To illustrate its role in practice,we present a case study on link activation in a multi-link operation(MLO)environment with multiple APs.Through theoretical discussion and simulation results,the study demonstrates how FRL can improve performance and reliability,paving the way for more adaptive and collaborative Wi-Fi networks in the era of Wi-Fi 7 and beyond.展开更多
Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remain...Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remains one of the security challenges. is paper proposes LinguTimeX,a new framework that combines natural language processing with arti cial intelligence,along with explainable Arti cial Intelligence(AI)not only to detect CTC but also to provide insights into the decision process.LinguTimeX performs multidimensional feature extraction by fusing linguistic attributes with temporal network patterns to identify covert channels precisely.LinguTimeX demonstrates strong e ectiveness in detecting CTC across multiple languages;namely English,Arabic,and Chinese.Speci cally,the LSTM and RNN models achieved F1 scores of 90%on the English dataset,89%on the Arabic dataset,and 88%on the Chinese dataset,showcasing their superior performance and ability to generalize across multiple languages. is highlights their robustness in detecting CTCs within security systems,regardless of the language or cultural context of the data.In contrast,the DeepForest model produced F1-scores ranging from 86%to 87%across the same datasets,further con rming its e ectiveness in CTC detection.Although other algorithms also showed reasonable accuracy,the LSTM and RNN models consistently outperformed them in multilingual settings,suggesting that deep learning models might be better suited for this particular problem.展开更多
Split Learning(SL)has been promoted as a promising collaborative machine learning technique designed to address data privacy and resource efficiency.Specifically,neural networks are divided into client and server subn...Split Learning(SL)has been promoted as a promising collaborative machine learning technique designed to address data privacy and resource efficiency.Specifically,neural networks are divided into client and server subnetworks in order to mitigate the exposure of sensitive data and reduce the overhead on client devices,thereby making SL particularly suitable for resource-constrained devices.Although SL prevents the direct transmission of raw data,it does not alleviate entirely the risk of privacy breaches.In fact,the data intermediately transmitted to the server sub-model may include patterns or information that could reveal sensitive data.Moreover,achieving a balance between model utility and data privacy has emerged as a challenging problem.In this article,we propose a novel defense approach that combines:(i)Adversarial learning,and(ii)Network channel pruning.In particular,the proposed adversarial learning approach is specifically designed to reduce the risk of private data exposure while maintaining high performance for the utility task.On the other hand,the suggested channel pruning enables the model to adaptively adjust and reactivate pruned channels while conducting adversarial training.The integration of these two techniques reduces the informativeness of the intermediate data transmitted by the client sub-model,thereby enhancing its robustness against attribute inference attacks without adding significant computational overhead,making it wellsuited for IoT devices,mobile platforms,and Internet of Vehicles(IoV)scenarios.The proposed defense approach was evaluated using EfficientNet-B0,a widely adopted compact model,along with three benchmark datasets.The obtained results showcased its superior defense capability against attribute inference attacks compared to existing state-of-the-art methods.This research’s findings demonstrated the effectiveness of the proposed channel pruning-based adversarial training approach in achieving the intended compromise between utility and privacy within SL frameworks.In fact,the classification accuracy attained by the attackers witnessed a drastic decrease of 70%.展开更多
The present study investigates the flow,heat,and mass transfer analysis in the bioconvection of nanofluid containing motile gyrotactic microorganisms through a semi-porous curved oscillatory channel with a magnetic fi...The present study investigates the flow,heat,and mass transfer analysis in the bioconvection of nanofluid containing motile gyrotactic microorganisms through a semi-porous curved oscillatory channel with a magnetic field.These microorganisms produce density gradients by swimming,which induces macroscopic convection flows in the fluid.This procedure improves the mass and heat transfer,illustrating the interaction between biological activity and fluid dynamics.Furthermore,instead of considering traditional Fourier's and Fick's law the energy and concentration equations are developed by incorporating Cattaneo-Christov double diffusion theory.Moreover,to examine the influence of thermophoresis and Brownian diffusions in the fluid we have adopted the Buongiorno nanofluid model.Due to the oscillation of the surface of the channel,the mathematical development of the considered flow problem is obtained in the form of partial differential equations via the curvilinear coordinate system.The convergent series solution of the governing flow equations is obtained after applying the homotopy analysis method(HAM).The effects of different pertinent flow parameters on velocity,motile microorganism density distribution,concentration,pressure,temperature,and skin friction coefficient are examined and discussed in detail with the help of graphs and tables.It is observed during the current study that the density of microorganisms is enhanced for higher values of Reynolds number,Peclet number,radius of curvature variable,and Lewis number.展开更多
基金supported in part by the National Natural Science Foundation of China under Grant 61601477, and 61601480
文摘Channelization typically realized by digital filter banks is an important topic in high frequency(HF) communication and software defined radios(SDR) areas. Channelization has a rigorous requirement for the characteristic of frequency response, e.g., steep transitional band and sharp decay. To address this issue, we investigated the feasibility and implementation of applying fast filter bank(FFB) in channelization in this paper. We analyzed the butterfly structure of FFB similar with fast Fourier transform(FFT), in which prototype sub-filters are cascaded to achieve a low complexity. Hence, it is suitable for designing filter bank with steep transitional band and sharp decay in stop-band. Moreover, we designed a pipelined structure of FFB to achieve a balance between area and performance. Design example shows that FFB has lower computational complexity compared with the other filter banks.
文摘A multistandard software-defined radio base station must perform non-uniform channelization of multiplexed frequency bands. Non-uniform channelization accounts for a significant portion of the digital signal processing workload in the base station receiver and can be difficult to realize in a physical implementation. In non-uniform channelization methods based on generalized DFT filter banks, large prototype filter orders are a significant issue for implementation. In this paper, a multistage filter design is applied to two different non-uniform generalized DFT-based channelizers in order to reduce their filter orders. To evaluate the approach, a TETRA and TEDS base station is used. Experimental results show that the new multistage design reduces both the number of coefficients and operations and leads to a more feasible design and practical physical implementation.
文摘Channel straightening in a naturally meandering river is a common historical trigger of channel incision which typically results in stream bank destabilization. Several of the larger river systems in the upland portion of the Yazoo River Basin have subjected channelization resulting in profound changes in the physical and geomorphological characteristics of these systems. Fish were sampled using electroshocking gear and hoop nets to evaluate the impact of stream bank destabilization and loss of habitat heterogeneity resulting from channelization on fish communities. While distinct differences in the fish communities were evident, only the Skuna appeared to have characteristics of a damaged system. More than 95% of the biomass was comprised of species reaching an adult length of less than 300 mm. The lotic omnivorous fishes that dominated the biomass from Skuna are often associated with smaller streams rather than rivers. Furthermore, 72% of the catch consisted of fish preferring littoral zone habitats. The shallow depth and lack of woody debris in Skuna provided a selective advantage for smaller species of fish that could use shoreline habitats as protection from the current. Based on results from the Skuna River, channel straightening that leads to channel incision, bank failure and over widening provide habitats too shallow to support a community of fishes typical of northern Mississippi riverine system. This information may be useful in making comparison of damaged riverine ecosystems and assist managers in determining impairment and success in the TMDL (Total Maximum Daily Load) process.
基金supported by the National Natural Science Foundation of China,Nos.82172196(to KX),82372507(to KX)the Natural Science Foundation of Hunan Province,China,No.2023JJ40804(to QZ)the Key Laboratory of Emergency and Trauma(Hainan Medical University)of the Ministry of Education,China,No.KLET-202210(to QZ)。
文摘Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,and necroptosis.Oligomerization of mitochondrial voltage-dependent anion channel 1 is an important pathological event in regulating cell death in retinal ischemia–reperfusion injury.However,its role in PANoptosis remains largely unknown.In this study,we demonstrated that voltage-dependent anion channel 1 oligomerization-mediated mitochondrial dysfunction was associated with PANoptosis in retinal ischemia–reperfusion injury.Inhibition of voltage-dependent anion channel 1 oligomerization suppressed mitochondrial dysfunction and PANoptosis in retinal cells subjected to ischemia–reperfusion injury.Mechanistically,mitochondria-derived reactive oxygen species played a central role in the voltagedependent anion channel 1-mediated regulation of PANoptosis by promoting PANoptosome assembly.Moreover,inhibiting voltage-dependent anion channel 1 oligomerization protected against PANoptosis in the retinas of rats subjected to ischemia–reperfusion injury.Overall,our findings reveal the critical role of voltage-dependent anion channel 1 oligomerization in regulating PANoptosis in retinal ischemia–reperfusion injury,highlighting voltage-dependent anion channel 1 as a promising therapeutic target.
文摘Lithium–sulfur(Li–S)batteries are promisingcandidates for next-generation energy storagegiven their high energy density and potential low cost.Chemically activated carbon(CAC)is often used fortheir cathodes,because it has a high specific surfacearea for sulfur loading.We have developed a pressurizedphysical activation(PPA)method that producedan activated carbon(PPAC)with a high specific surfacearea comparable to that of CAC.The pore structure of PPAC could be changed and its use as a cathode material for Li–Sbatteries was investigated.Battery tests at different capacity rates(C-rates)showed that it had a much improved high-rate performancewith a discharge capacity of 900 mAh/(g of sulfur)at 1 C,in contrast to only 600 mAh/(g of sulfur)for CAC.Porestructure analyses showed that PPAC prepared at a high activation temperature(1000℃)had unusual channel-like mesoporesbetween the microdomains that are the basic structural units of artificial carbon materials.These are connected to microporesdeveloped in each microdomain,and deliver ions from the surroundings to the internal pores and vice versa.The well-developedmicropores and mesopores of PPAC respectively ensured the high adsorption of lithium polysulfides and a high rate ofion diffusion.Compared to CAC,PPAC is a high-performance,low-cost cathode material that is promising for use in futureLi–S batteries.
基金supported by ANID-FONDECYT 1200908(to JF),ANID-FONDECYT 1211082 and 1250856(to GEY)by the Millennium Nucleus for the Study of Pain NCN19_038(Mi Nu SPain)(to GEY)funded by the ANID scholarship 21201176。
文摘Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and disease,the search for new compounds that modulate these proteins is still relevant.Traditional medicine has long been a rich source of neuroactive compounds.For example,the indigenous Mapuche people have used the leaves and bark of the Drimys winteri tree for centuries to treat various diseases.Consequently,several studies have investigated the biological effects of compounds in Drimys winteri,highlighting sesquiterpenes such asα-humulene,drimenin,polygodial,andα-,β-,γ-eudesmol.However,there is currently no literature review focusing on the ability of these sesquiterpenes to modulate ion channels.This review summarizes the current knowledge about neuroactive compounds found in Drimys winteri,with special emphasis on their direct actions on neuronal ion channels.Several Drimys winteri sesquiterpenes modulate a diverse array of neuronal ion channels,including transient receptor potential channels,gamma-aminobutyric acid A receptors,nicotinic acetylcholine receptors,and voltage-dependent Ca^(2+)and Na^(+)channels.Interestingly,the modulation of these molecular targets by Drimys winteri sesquiterpenes correlates with their therapeutic actions.The promiscuous pharmacological profile of Drimys winteri sesquiterpenes suggests they modulate multiple protein targets in vivo,making them potentially useful for treating complex,multifactorial diseases.Further studies at the molecular level may aid in developing multitargeted drugs with enhanced therapeutic effects.
基金supported by the Natural Science Foundation of Shandong Province under Grant ZR2024MF062the open research fund of National Mobile Communications Research Laboratory,Southeast University under Grants 2025D03+1 种基金the Future Plan Program for Young Scholars of Shandong University,and the Innovation and Technology Support Program for Young Scholars of Colleges and Universities in Shandong Province under Grant 2022KJ009The B6G R&D Group in Shandong University is greatly thanked for channel measurements.
文摘The smart meter communication system has substantial application value for the construction and upgrading of the entire power system.The deployment of the transmitter(Tx)of the smart meter system in the residential scenarios is vexed by the need for more theoretical support.This paper mainly studies the communication channel between the Tx at semibasement and receiver(Rx)at outdoor.The design of an effective communication system relies on an accurate understanding of channel characteristics.Channel measurements and ray-tracing channel modeling are conducted to obtain channel data.The influence of different positions at same semi-basement is studied.Typical channel characteristics are analyzed,such as power delay profile(PDP),power angular profile(PAP),root-mean-square(RMS)delay spread(DS),channel capacity,received power,and path loss.The influence of different semi-basement placements and different floor heights is also compared.Besides,the channel measurements and simulation data fit well,which can illustrate the validity and reliability of the acquired channel data.This paper can provide theoretical support for the design and optimization of smart meter communication systems in semi-basement scenarios.
基金supported in part by the National Key Research and Development Program of China(2021YFB2900501)in part by the Shaanxi Science and Technology Innovation Team(2023-CX-TD-03)+3 种基金in part by the Science and Technology Program of Shaanxi Province(2021GXLH-Z-038)in part by the Natural Science Foundation of Hunan Province(2023JJ40607 and 2023JJ50045)in part by the Scientific Research Foundation of Hunan Provincial Education Department(23B0713 and 24B0603)in part by the National Natural Science Foundation of China(62401371,62101275,and 62372070).
文摘(Quasi-)closed-form results for the statistical properties of unmanned aerial vehicle(UAV)airto-ground channels are derived for the first time using a novel spatial-vector-based method from a threedimensional(3-D)arbitrary-elevation one-cylinder model.The derived results include a closed-form expression for the space-time correlation function and some quasi-closed-form ones for the space-Doppler power spectrum density,the level crossing rate,and the average fading duration,which are shown to be the generalizations of those previously obtained from the two-dimensional(2-D)one-ring model and the 3-D low-elevation one-cylinder model for terrestrial mobile-to-mobile channels.The close agreements between the theoretical results and the simulations as well as the measurements validate the utility of the derived channel statistics.Based on the derived expressions,the impacts of some parameters on the channel characteristics are investigated in an effective,efficient,and explicable way,which leads to a general guideline on the manual parameter estimation from the measurement description.
文摘A terrestrial relay-aided reconfigurable intelligent surface(RIS)system with decode,re-encode and forward(DRF)relaying scheme is presented where the RIS effectively contributes to both sourceto-destination and relay-to-destination signaling.While in the conventional decode and forward(DF)relaying scheme,the source signal is merely duplicated in the relay and the time intervals are equally allocated to the source and relay nodes,this paper considers DRF relaying scheme where versatile time-sharing is adopted for the source and relay nodes which can be optimized based on the relative coordinates of the involved nodes.Two protocols namely unidirectional connection(UC)and bidirectional connection(BC)are proposed based on the source awareness from the relay’s successful reception.The outage probability(OP)performance for both protocols and both DF and DRF relaying schemes is analyzed and tight approximations are obtained.The numerical results show the out-performance of the DRF over the DF relaying scheme in the both UC and BC protocols.Equipped with the obtained system OP,the system throughput is defined and the optimum system throughput is obtained by optimizing the system rate and the timesharing between the source and the relay.Analytical results are corroborated in the numerical examples.
基金supported by National Natural Science Foundation(NNSF)of China under Grant 62001351the Foundation of National Key Laboratory of Electromagnetic Environment(6142403220202)the Stability Support Fund for Basic Military Industrial Research Institutes(A240104130).
文摘The orthogonal time frequency space(OTFS)modulation is a novel modulation scheme that can effectively cope with the high Doppler expansion caused by high mobility.Since it modulates data on delay-Doppler(DD)domain and makes full use of the sparse characteristics of DD domain,it has been widely studied to design efficient channel estimation and signal detection schemes.In this paper,we design a novel superimposed pilot pattern with transition band,which replaces the traditional embedded pilot(EP)guard zero-symbols,and perform a two-stage channel estimation.In the first stage,we fully utilize the dispersion characteristics of OTFS signal in DD domain,and use threshold decision to make coarse channel estimation.In the second stage,we use the results of the coarse estimation for iterative signal detection and accurate channel estimation.During the second stage,we make full use of the sparsity of the channel in DD domain,remodel the received signal into the form of sparse channel vector multiplied by channel coefficient matrix,and introduce Doppler index segmentation factor(DISF)to subdivide the Doppler index to solve the problem of fractional Doppler.Simulations reveal that,the scheme proposed in this paper has higher spectral efficiency compared with traditional EP scheme and lower peak-to-average power ratio(PAPR)compared with traditional superimposed pilot scheme.
基金financially supported by the Key R&D Program of Shandong Province(2022SFGC0801)the National Natural Science Foundation of China(No.22005162 and 22175009)the Natural Science Foundation of Shandong Province(No.ZR2020QE093)。
文摘Osmotic energy,existing between the seawater and river water,is a renewable energy source,which can be directly converted into electricity by ion-exchange membranes(IEM).In traditional IEMs,the ion transport channels are formed by nanophase separation of hydrophilic ion carriers and hydrophobic segments.It is difficult to realize high-density ion channels with controlled spatial arrangement and length scale of ion carriers.Herein,we construct high-density 1D ion wires as transmission channels.Through molecular design,hydrophilic imidazole groups and hydrophobic alkyl tails were introduced into the repeat units,which self-assembled into 1D ion transporting core and protecting shell along the main chains.The areal density of the ionic wire arrays is up to~10^(12)cm^(-2),which is the highest value.The ionic wires ensure both high ion flux transport and high selectivity,achieving an ultrahigh-power density of 40.5 W m^(-2)at a 500-fold salinity gradient.Besides,the ionic wire array membrane is well recyclable and antibacterial.The ionic wires provide novel concept for next generation of high-performance membranes.
基金supported in part by the Fundamental Research Funds for the Central Universities under Grant 2242022k60004in part by the National Natural Science Foundation of China(NSFC)under Grants 62261160576,624B2036,W2421087,62422105+1 种基金in part by the Young Elite Scientists Sponsorship Program by CAST 2022QNRC001,and the“Zhishan”Scholars Programs of Southeast Universityin part by the Key Technologies R&D Program of Jiangsu(Prospective and Key Technologies for Industry)under Grants BE2023022,BE2023022-1 and BE2023022-2.
文摘Reconfigurable intelligent surfaces(RISs)not only assist communication but also help the localization of user equipment(UE).This study focuses on indoor localization of UE with a single access point(AP)and multiple RISs.First,we propose a two-stage channel estimation scheme where RIS phase shifts are tuned to obtain multiple channel soundings.In the first stage,the newtonized orthogonal matching pursuit algorithm extracts the parameters of multiple paths from the received signals.Then,the LOS path and RISreflected paths are identified.In the second stage,the estimated path gains of RIS-reflected paths with different phase shifts are utilized to determine the angle of arrival(AOA)at the RIS by obtaining the angular pseudo spectrum.Consequently,by taking the AP and RISs as reference points,the linear least squares estimator can locate UE with the estimated AOAs.Simulation results show that the proposed algorithm can realize centimeter-level localization accuracy in the discussed scenarios.Moreover,the higher accuracy of pseudo spectrum,a larger number of channel soundings,and a larger number of reference points can realize higher localization accuracy of UE.
基金supported by the National Natural Sci-ence Foundation of China(Grant Nos.12404410,12564049,11964013,61975077)the National Key Research and De-velopment Program of China(Grant No.2024ZD0300900)the Jiangxi Provincial Natural Science Foundation(Grant No.20242BAB26009).
文摘Einstein–Podolsky–Rosen(EPR)steering is an important resource for one-sided device-independent quantum information processing.This steering property can be destroyed by the interaction between a quantum system and its environment in practical applications.In this paper,we employ the characteristic function representation of probability distributions to investigate the quantum steering of two-mode continuous-variable states in a laser channel,where both the gain factor and the loss effect are taken into account.Firstly,we analyse the steering time of the two-mode squeezed vacuum state under one-mode and two-mode laser channels,respectively.We find that the gain process introduces additional noise into the two-mode squeezed vacuum state,thereby reducing the steerable time.Secondly,by quantifying EPR steering,we show that two-side loss exhibits smaller steerability than one-side loss,although they share the same two-way steerable time.In addition,we find that the more-gained party can steer the other party’s state,whereas the other party cannot steer the gained party beyond a certain threshold value.In this sense,the gain effect in one party appears to be equivalent to the loss effect in the other party.Our results pave the way for the distillation of EPR steering and quantum information processing in practical quantum channels.
基金funded by the Deanship of Scientific Research(DSR)at King Abdulaziz University,Jeddah,Saudi Arabia,grant number RG-2-611-42(A.O.A.).
文摘Wi-Fi technology has evolved significantly since its introduction in 1997,advancing to Wi-Fi 6 as the latest standard,with Wi-Fi 7 currently under development.Despite these advancements,integrating machine learning into Wi-Fi networks remains challenging,especially in decentralized environments with multiple access points(mAPs).This paper is a short review that summarizes the potential applications of federated reinforcement learning(FRL)across eight key areas of Wi-Fi functionality,including channel access,link adaptation,beamforming,multi-user transmissions,channel bonding,multi-link operation,spatial reuse,and multi-basic servic set(multi-BSS)coordination.FRL is highlighted as a promising framework for enabling decentralized training and decision-making while preserving data privacy.To illustrate its role in practice,we present a case study on link activation in a multi-link operation(MLO)environment with multiple APs.Through theoretical discussion and simulation results,the study demonstrates how FRL can improve performance and reliability,paving the way for more adaptive and collaborative Wi-Fi networks in the era of Wi-Fi 7 and beyond.
基金This study is financed by the European Union-NextGenerationEU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,Project No.BG-RRP-2.013-0001.
文摘Covert timing channels(CTC)exploit network resources to establish hidden communication pathways,posing signi cant risks to data security and policy compliance.erefore,detecting such hidden and dangerous threats remains one of the security challenges. is paper proposes LinguTimeX,a new framework that combines natural language processing with arti cial intelligence,along with explainable Arti cial Intelligence(AI)not only to detect CTC but also to provide insights into the decision process.LinguTimeX performs multidimensional feature extraction by fusing linguistic attributes with temporal network patterns to identify covert channels precisely.LinguTimeX demonstrates strong e ectiveness in detecting CTC across multiple languages;namely English,Arabic,and Chinese.Speci cally,the LSTM and RNN models achieved F1 scores of 90%on the English dataset,89%on the Arabic dataset,and 88%on the Chinese dataset,showcasing their superior performance and ability to generalize across multiple languages. is highlights their robustness in detecting CTCs within security systems,regardless of the language or cultural context of the data.In contrast,the DeepForest model produced F1-scores ranging from 86%to 87%across the same datasets,further con rming its e ectiveness in CTC detection.Although other algorithms also showed reasonable accuracy,the LSTM and RNN models consistently outperformed them in multilingual settings,suggesting that deep learning models might be better suited for this particular problem.
基金supported by a grant(No.CRPG-25-2054)under the Cybersecurity Research and Innovation Pioneers Initiative,provided by the National Cybersecurity Authority(NCA)in the Kingdom of Saudi Arabia.
文摘Split Learning(SL)has been promoted as a promising collaborative machine learning technique designed to address data privacy and resource efficiency.Specifically,neural networks are divided into client and server subnetworks in order to mitigate the exposure of sensitive data and reduce the overhead on client devices,thereby making SL particularly suitable for resource-constrained devices.Although SL prevents the direct transmission of raw data,it does not alleviate entirely the risk of privacy breaches.In fact,the data intermediately transmitted to the server sub-model may include patterns or information that could reveal sensitive data.Moreover,achieving a balance between model utility and data privacy has emerged as a challenging problem.In this article,we propose a novel defense approach that combines:(i)Adversarial learning,and(ii)Network channel pruning.In particular,the proposed adversarial learning approach is specifically designed to reduce the risk of private data exposure while maintaining high performance for the utility task.On the other hand,the suggested channel pruning enables the model to adaptively adjust and reactivate pruned channels while conducting adversarial training.The integration of these two techniques reduces the informativeness of the intermediate data transmitted by the client sub-model,thereby enhancing its robustness against attribute inference attacks without adding significant computational overhead,making it wellsuited for IoT devices,mobile platforms,and Internet of Vehicles(IoV)scenarios.The proposed defense approach was evaluated using EfficientNet-B0,a widely adopted compact model,along with three benchmark datasets.The obtained results showcased its superior defense capability against attribute inference attacks compared to existing state-of-the-art methods.This research’s findings demonstrated the effectiveness of the proposed channel pruning-based adversarial training approach in achieving the intended compromise between utility and privacy within SL frameworks.In fact,the classification accuracy attained by the attackers witnessed a drastic decrease of 70%.
文摘The present study investigates the flow,heat,and mass transfer analysis in the bioconvection of nanofluid containing motile gyrotactic microorganisms through a semi-porous curved oscillatory channel with a magnetic field.These microorganisms produce density gradients by swimming,which induces macroscopic convection flows in the fluid.This procedure improves the mass and heat transfer,illustrating the interaction between biological activity and fluid dynamics.Furthermore,instead of considering traditional Fourier's and Fick's law the energy and concentration equations are developed by incorporating Cattaneo-Christov double diffusion theory.Moreover,to examine the influence of thermophoresis and Brownian diffusions in the fluid we have adopted the Buongiorno nanofluid model.Due to the oscillation of the surface of the channel,the mathematical development of the considered flow problem is obtained in the form of partial differential equations via the curvilinear coordinate system.The convergent series solution of the governing flow equations is obtained after applying the homotopy analysis method(HAM).The effects of different pertinent flow parameters on velocity,motile microorganism density distribution,concentration,pressure,temperature,and skin friction coefficient are examined and discussed in detail with the help of graphs and tables.It is observed during the current study that the density of microorganisms is enhanced for higher values of Reynolds number,Peclet number,radius of curvature variable,and Lewis number.