In a Nature Physics report published in late September 2024[1],a team of scientists and engineers at Sandia National Laboratories(Albuquerque,NM,USA)described the results of a laboratory experiment showing that a nucl...In a Nature Physics report published in late September 2024[1],a team of scientists and engineers at Sandia National Laboratories(Albuquerque,NM,USA)described the results of a laboratory experiment showing that a nuclear blast could create a burst of X-rays powerful enough to change the path of a large asteroid that might one day be on a collision course with Earth.展开更多
Urumqi Glacier No. 1 is a representative glacier in the inland areas of Central Asia and is the only Chinese reference glacier in the World Glacier Monitoring Service. In this study, we explored multi-decadal variatio...Urumqi Glacier No. 1 is a representative glacier in the inland areas of Central Asia and is the only Chinese reference glacier in the World Glacier Monitoring Service. In this study, we explored multi-decadal variations in the flow velocity of the glacier and the influencing factors based on continuous field observations and path coefficient analysis. Results show that the glacier flow velocity decreased from 5.5 m/a in 1980/1981 to 3.3 m/a in 2010/2011. The annual variation in the direction of glacier flow velocity in the western branch and eastern branch was less than 1°–3°, and the change of glacier flow velocity in the western branch was more dramatic than that in the eastern branch. Glacier flow velocity was influenced by glacier morphology（including glacier area, glacier length, and ice thickness）, glacier mass balance and local climate conditions（air temperature and precipitation）, the glacier morphology being the leading factor. The long-term flow velocity data set of Urumqi Glacier No. 1 contributes to a better understanding of glacier dynamics within the context of climatic warming.展开更多
Controlling the tissue temperature rise during retinal laser therapy is essential for predictable outcomes,especially at non-damaging settings.We demonstrate a method for determining the temperature rise in the retina...Controlling the tissue temperature rise during retinal laser therapy is essential for predictable outcomes,especially at non-damaging settings.We demonstrate a method for determining the temperature rise in the retina using phasesensitive optical coherence tomography(pOCT)in vivo.Measurements based on the thermally induced optical path length changes(ΔOPL)in the retina during a 10-ms laser pulse allow detection of the temperature rise with a precision less than 1℃,which is sufficient for calibration of the laser power for patient-specific non-damaging therapy.We observed a significant difference in confinement of the retinal deformations between the normal and the degenerate retina:in wild-type rats,thermal deformations are localized between the retinal pigment epithelium(RPE)and the photoreceptors’inner segments(IS),as opposed to a deep penetration of the deformations into the inner retinal layers in the degenerate retina.This implies the presence of a structural component within healthy photoreceptors that dampens the tissue expansion induced by the laser heating of the RPE and pigmented choroid.We hypothesize that the thin and soft cilium connecting the inner and outer segments(IS,OS)of photoreceptors may absorb the deformations of the OS and thereby preclude the tissue expansion further inward.Striking difference in the confinement of the retinal deformations induced by a laser pulse in healthy and degenerate retina may be used as a biomechanical diagnostic tool for the characterization of photoreceptors degeneration.展开更多
文摘In a Nature Physics report published in late September 2024[1],a team of scientists and engineers at Sandia National Laboratories(Albuquerque,NM,USA)described the results of a laboratory experiment showing that a nuclear blast could create a burst of X-rays powerful enough to change the path of a large asteroid that might one day be on a collision course with Earth.
基金funded the National Natural Science Foundation of China (41501010, 41401611)the Funds for Creative Research Groups of China (41121001)the Youth Innovation Promotion Association of Chinese Academy of Sciences
文摘Urumqi Glacier No. 1 is a representative glacier in the inland areas of Central Asia and is the only Chinese reference glacier in the World Glacier Monitoring Service. In this study, we explored multi-decadal variations in the flow velocity of the glacier and the influencing factors based on continuous field observations and path coefficient analysis. Results show that the glacier flow velocity decreased from 5.5 m/a in 1980/1981 to 3.3 m/a in 2010/2011. The annual variation in the direction of glacier flow velocity in the western branch and eastern branch was less than 1°–3°, and the change of glacier flow velocity in the western branch was more dramatic than that in the eastern branch. Glacier flow velocity was influenced by glacier morphology（including glacier area, glacier length, and ice thickness）, glacier mass balance and local climate conditions（air temperature and precipitation）, the glacier morphology being the leading factor. The long-term flow velocity data set of Urumqi Glacier No. 1 contributes to a better understanding of glacier dynamics within the context of climatic warming.
基金funded by the National Institutes of Health(U01 EY032055)Air Force Office of Scientific Research(FA9550-20-1-0186)Research to Prevent Blindness.
文摘Controlling the tissue temperature rise during retinal laser therapy is essential for predictable outcomes,especially at non-damaging settings.We demonstrate a method for determining the temperature rise in the retina using phasesensitive optical coherence tomography(pOCT)in vivo.Measurements based on the thermally induced optical path length changes(ΔOPL)in the retina during a 10-ms laser pulse allow detection of the temperature rise with a precision less than 1℃,which is sufficient for calibration of the laser power for patient-specific non-damaging therapy.We observed a significant difference in confinement of the retinal deformations between the normal and the degenerate retina:in wild-type rats,thermal deformations are localized between the retinal pigment epithelium(RPE)and the photoreceptors’inner segments(IS),as opposed to a deep penetration of the deformations into the inner retinal layers in the degenerate retina.This implies the presence of a structural component within healthy photoreceptors that dampens the tissue expansion induced by the laser heating of the RPE and pigmented choroid.We hypothesize that the thin and soft cilium connecting the inner and outer segments(IS,OS)of photoreceptors may absorb the deformations of the OS and thereby preclude the tissue expansion further inward.Striking difference in the confinement of the retinal deformations induced by a laser pulse in healthy and degenerate retina may be used as a biomechanical diagnostic tool for the characterization of photoreceptors degeneration.
