Micro/nanorobots represent a groundbreaking advancement in nanotechnology,with applications spanning medicine,envi-ronmental remediation,and industrial processes.A major challenge in their development is achieving eff...Micro/nanorobots represent a groundbreaking advancement in nanotechnology,with applications spanning medicine,envi-ronmental remediation,and industrial processes.A major challenge in their development is achieving efficient and bio-compatible propulsion.Enzyme-driven propulsion,particularly using catalase,offers a promising solution due to its ability to decompose hydrogen peroxide(H2O2)into water and oxygen,generating thrust for autonomous movement.Compared to metal-based catalysts,catalase-powered systems exhibit superior biocompatibility and lower toxicity,making them ideal for biomedical applications.This review explores the role of catalase in micro/nanorobot propulsion,highlighting self-propulsion mechanisms,different nanorobot types,and their applications in drug delivery,infection treatment,cancer therapy,and biosensing.Additionally,recent advancements in biodegradable enzyme-powered nanorobots and their poten-tial in overcoming biological barriers are discussed.With further research,catalase-driven nanorobots could revolutionize targeted therapy and diagnostic techniques,paving the way for innovative solutions in nanomedicine.展开更多
基金The Large Research Group Project under grant number RGP.02/516/45.
文摘Micro/nanorobots represent a groundbreaking advancement in nanotechnology,with applications spanning medicine,envi-ronmental remediation,and industrial processes.A major challenge in their development is achieving efficient and bio-compatible propulsion.Enzyme-driven propulsion,particularly using catalase,offers a promising solution due to its ability to decompose hydrogen peroxide(H2O2)into water and oxygen,generating thrust for autonomous movement.Compared to metal-based catalysts,catalase-powered systems exhibit superior biocompatibility and lower toxicity,making them ideal for biomedical applications.This review explores the role of catalase in micro/nanorobot propulsion,highlighting self-propulsion mechanisms,different nanorobot types,and their applications in drug delivery,infection treatment,cancer therapy,and biosensing.Additionally,recent advancements in biodegradable enzyme-powered nanorobots and their poten-tial in overcoming biological barriers are discussed.With further research,catalase-driven nanorobots could revolutionize targeted therapy and diagnostic techniques,paving the way for innovative solutions in nanomedicine.