Optimal health during pregnancy is crucial for ensuring the well-being of the mother and the developing fetus.This article is focused on the impact of oral health and the role of personalized oral hygiene management i...Optimal health during pregnancy is crucial for ensuring the well-being of the mother and the developing fetus.This article is focused on the impact of oral health and the role of personalized oral hygiene management in addressing prevalent dental issues among pregnant women,with particular emphasis on periodontal disease and dental caries.Despite the high prevalence of these dental problems and their association with obstetric complications such as pre-term birth and low birth weight,many pregnant women do not receive adequate dental care.This gap in care is often due to misconceptions about the safety of dental treat-ments during pregnancy and lack of awareness on the part of healthcare profes-sionals.Appreciations of the impacts of oral health and personalization of oral hygiene strategies such as tailored education and support,have proven effective in improving oral health in this population.Significant reductions in the incidence of caries and periodontal disease may be achieved by adapting care to the specific needs of each patient,thereby enhancing maternal and fetal health outcomes.Integration of personalized oral hygiene management into maternal health pro-grams and enhancement of ongoing education for pregnant women and healthcare professionals are essential steps in the reduction of pregnancy-related risks and improvement of maternal and neonatal well-being.Core Tip:In this article,we reviewed a recent study on the effects of personalized oral hygiene management on the oral health of pregnant women,as discussed in the article by Men et al.The study demonstrated that personalized oral hygiene interventions significantly improved oral health outcomes during pregnancy by reducing the prevalence of dental caries and periodontal disease.We emphasized the importance of individualized oral care programs that integrate education and tailored support,and we highlighted their significance in enhancing maternal and fetal health.This approach underscores the need for incorporating personalized oral hygiene management into routine prenatal care in order to optimize health outcomes.CONCLUSION This article emphasizes the critical role of personalized oral hygiene management in improving oral health during pregnancy.By tailoring oral care strategies to individual needs,significant improvements in dental health may be achieved,as evidenced by the reduced CAT scores observed in the experimental group in the study by Men et al[25].This personalized approach not only addresses common oral issues such as dental caries and periodontal disease but also underscores the broader implications for maternal and fetal health.Despite the positive results,there remains a gap in consistency in the application of oral health practices during pregnancy,partly due to misconceptions and lack of awareness among patients and healthcare providers.Future research should aim at validating these findings across diverse populations,investigating the impact of oral hygiene interventions at various stages of pregnancy,and evaluating their long-term effects on maternal and fetal health.Integrating personalized oral hygiene management into maternal health programs and promoting continuous education for pregnant women and healthcare professionals are essential steps toward enhancing overall health outcomes.By proactively managing oral health,the risks associated with pregnancy may be reduced while improving maternal and neonatal well-being.展开更多
Objective:To statistically analyze the prevalence of dental caries among preschool children and explore the application effect of behavioral intervention.Methods:The study period was from May 2024 to May 2025.Preschoo...Objective:To statistically analyze the prevalence of dental caries among preschool children and explore the application effect of behavioral intervention.Methods:The study period was from May 2024 to May 2025.Preschool children with dental caries(n=114)admitted during this period were selected as the research subjects.They were divided into observation and control groups based on their admission number,with 57 cases in each group.Intervention indicators were compared between the groups.Results:Among all the children,the prevalence of dental caries at different age stages of preschool age(3–6 years old)showed that the caries rate increased with age,and there were significant differences in caries rates among different age groups(P<0.05).The total treatment compliance rate in the observation group was higher than that in the control group(P<0.05),and the new caries rate in the observation group was lower than that in the control group(P<0.05).After intervention,all indicators of the SESS in the observation group were better than those in the control group(P<0.05).Conclusion:The caries rate among preschool children is relatively high and increases with age.Active behavioral intervention facilitates better cooperation with clinical treatment among children with caries,significantly enhances self-efficacy,and significantly reduces the caries rate.展开更多
The study analyzed the effect of dental caries prevention strategies on caries incidence,oral hygiene status and parental satisfaction.The results showed that the comprehensive application of multiple prevention strat...The study analyzed the effect of dental caries prevention strategies on caries incidence,oral hygiene status and parental satisfaction.The results showed that the comprehensive application of multiple prevention strategies can significantly reduce the incidence of dental caries,improve oral hygiene and improve parental satisfaction.By reviewing the literature at home and abroad in recent years,this paper aims to explore the effect of childhood caries prevention strategies in oral clinical application,and provides scientific basis and practical guidance for the prevention of childhood caries in oral clinical work.展开更多
Dental caries,a chronic disease characterized by tooth decay,occupies the second position in terms of disease burden and is primarily caused by cariogenic bacteria,especially Streptococcus mutans,because of its acidog...Dental caries,a chronic disease characterized by tooth decay,occupies the second position in terms of disease burden and is primarily caused by cariogenic bacteria,especially Streptococcus mutans,because of its acidogenic,aciduric,and biofilm-forming capabilities.Developing novel targeted anti-virulence agents is always a focal point in caries control to overcome the limitations of conventional anti-virulence agents.The current study represents an up-to-date review of in silico approaches of drug design against dental caries,which have emerged more and more powerful complementary to biochemical attempts.Firstly,we categorize the in silico approaches into computer-aided drug design(CADD)and AI-assisted drug design(AIDD)and highlight the specific methods and models they contain respectively.Subsequently,we detail the design of anti-virulence drugs targeting single or multiple cariogenic virulence targets of S.mutans,such as glucosyltransferases(Gtfs),antigen I/II(AgI/II),sortase A(SrtA),the VicRK signal transduction system and superoxide dismutases(SODs).Finally,we outline the current opportunities and challenges encountered in this field to aid future endeavors and applications of CADD and AIDD in anti-virulence drug design.展开更多
Dental diseases,especially dental caries,are significant issues affecting population health worldwide.Dental caries has been listed by the World Health Organization as one of the three key diseases to be prevented and...Dental diseases,especially dental caries,are significant issues affecting population health worldwide.Dental caries has been listed by the World Health Organization as one of the three key diseases to be prevented and treated,following cardiovascular diseases and cancer.It has a high incidence rate and a wide distribution,posing a serious threat to people’s oral health and quality of life[1-5].With the intensification of the global aging population and changes in dietary habits,the incidence of dental diseases is on the rise,becoming a public health problem that cannot be ignored.Therefore,exploring new theories for dental disease prevention and treatment,such as the bioelectrochemical theory and the mineralization and anti-electricity new theory,and discussing their application prospects can provide more effective scientific bases and methods for the prevention and treatment of dental diseases,which is of great practical significance,especially for children and the elderly.展开更多
文摘Optimal health during pregnancy is crucial for ensuring the well-being of the mother and the developing fetus.This article is focused on the impact of oral health and the role of personalized oral hygiene management in addressing prevalent dental issues among pregnant women,with particular emphasis on periodontal disease and dental caries.Despite the high prevalence of these dental problems and their association with obstetric complications such as pre-term birth and low birth weight,many pregnant women do not receive adequate dental care.This gap in care is often due to misconceptions about the safety of dental treat-ments during pregnancy and lack of awareness on the part of healthcare profes-sionals.Appreciations of the impacts of oral health and personalization of oral hygiene strategies such as tailored education and support,have proven effective in improving oral health in this population.Significant reductions in the incidence of caries and periodontal disease may be achieved by adapting care to the specific needs of each patient,thereby enhancing maternal and fetal health outcomes.Integration of personalized oral hygiene management into maternal health pro-grams and enhancement of ongoing education for pregnant women and healthcare professionals are essential steps in the reduction of pregnancy-related risks and improvement of maternal and neonatal well-being.Core Tip:In this article,we reviewed a recent study on the effects of personalized oral hygiene management on the oral health of pregnant women,as discussed in the article by Men et al.The study demonstrated that personalized oral hygiene interventions significantly improved oral health outcomes during pregnancy by reducing the prevalence of dental caries and periodontal disease.We emphasized the importance of individualized oral care programs that integrate education and tailored support,and we highlighted their significance in enhancing maternal and fetal health.This approach underscores the need for incorporating personalized oral hygiene management into routine prenatal care in order to optimize health outcomes.CONCLUSION This article emphasizes the critical role of personalized oral hygiene management in improving oral health during pregnancy.By tailoring oral care strategies to individual needs,significant improvements in dental health may be achieved,as evidenced by the reduced CAT scores observed in the experimental group in the study by Men et al[25].This personalized approach not only addresses common oral issues such as dental caries and periodontal disease but also underscores the broader implications for maternal and fetal health.Despite the positive results,there remains a gap in consistency in the application of oral health practices during pregnancy,partly due to misconceptions and lack of awareness among patients and healthcare providers.Future research should aim at validating these findings across diverse populations,investigating the impact of oral hygiene interventions at various stages of pregnancy,and evaluating their long-term effects on maternal and fetal health.Integrating personalized oral hygiene management into maternal health programs and promoting continuous education for pregnant women and healthcare professionals are essential steps toward enhancing overall health outcomes.By proactively managing oral health,the risks associated with pregnancy may be reduced while improving maternal and neonatal well-being.
文摘Objective:To statistically analyze the prevalence of dental caries among preschool children and explore the application effect of behavioral intervention.Methods:The study period was from May 2024 to May 2025.Preschool children with dental caries(n=114)admitted during this period were selected as the research subjects.They were divided into observation and control groups based on their admission number,with 57 cases in each group.Intervention indicators were compared between the groups.Results:Among all the children,the prevalence of dental caries at different age stages of preschool age(3–6 years old)showed that the caries rate increased with age,and there were significant differences in caries rates among different age groups(P<0.05).The total treatment compliance rate in the observation group was higher than that in the control group(P<0.05),and the new caries rate in the observation group was lower than that in the control group(P<0.05).After intervention,all indicators of the SESS in the observation group were better than those in the control group(P<0.05).Conclusion:The caries rate among preschool children is relatively high and increases with age.Active behavioral intervention facilitates better cooperation with clinical treatment among children with caries,significantly enhances self-efficacy,and significantly reduces the caries rate.
文摘The study analyzed the effect of dental caries prevention strategies on caries incidence,oral hygiene status and parental satisfaction.The results showed that the comprehensive application of multiple prevention strategies can significantly reduce the incidence of dental caries,improve oral hygiene and improve parental satisfaction.By reviewing the literature at home and abroad in recent years,this paper aims to explore the effect of childhood caries prevention strategies in oral clinical application,and provides scientific basis and practical guidance for the prevention of childhood caries in oral clinical work.
基金supported by the Sichuan Science and Technology Program,China(Grant Nos.:2023ZYD0105 and 2023YFS0343)。
文摘Dental caries,a chronic disease characterized by tooth decay,occupies the second position in terms of disease burden and is primarily caused by cariogenic bacteria,especially Streptococcus mutans,because of its acidogenic,aciduric,and biofilm-forming capabilities.Developing novel targeted anti-virulence agents is always a focal point in caries control to overcome the limitations of conventional anti-virulence agents.The current study represents an up-to-date review of in silico approaches of drug design against dental caries,which have emerged more and more powerful complementary to biochemical attempts.Firstly,we categorize the in silico approaches into computer-aided drug design(CADD)and AI-assisted drug design(AIDD)and highlight the specific methods and models they contain respectively.Subsequently,we detail the design of anti-virulence drugs targeting single or multiple cariogenic virulence targets of S.mutans,such as glucosyltransferases(Gtfs),antigen I/II(AgI/II),sortase A(SrtA),the VicRK signal transduction system and superoxide dismutases(SODs).Finally,we outline the current opportunities and challenges encountered in this field to aid future endeavors and applications of CADD and AIDD in anti-virulence drug design.
文摘Dental diseases,especially dental caries,are significant issues affecting population health worldwide.Dental caries has been listed by the World Health Organization as one of the three key diseases to be prevented and treated,following cardiovascular diseases and cancer.It has a high incidence rate and a wide distribution,posing a serious threat to people’s oral health and quality of life[1-5].With the intensification of the global aging population and changes in dietary habits,the incidence of dental diseases is on the rise,becoming a public health problem that cannot be ignored.Therefore,exploring new theories for dental disease prevention and treatment,such as the bioelectrochemical theory and the mineralization and anti-electricity new theory,and discussing their application prospects can provide more effective scientific bases and methods for the prevention and treatment of dental diseases,which is of great practical significance,especially for children and the elderly.
