[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patie...[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patients diagnosed with CSR who received treatment at the International Mongolian Hospital of Inner Mongolia between October 2021 and October 2022 were selected and randomly divided into two groups:A test group and a control group,with 60 patients in each group.The patients in the test group received Mongolian medicine silver needle combined with cupping and bloodletting therapy,following the principles of syndrome differentiation in Mongolian medicine.In contrast,the patients in the control group received only the Mongolian medicine silver needle therapy.After treatment,the Mongolian medicine syndrome scores,visual analogue scale(VAS)scores,and total clinical therapeutic effects in the two groups of patients were compared both prior to and following the treatment.[Results]The improvement in VAS and Mongolian medicine syndrome scores in the test group was greater than that in the control group,with a statistically significant difference(P<0.05).The scores of the test group surpassed those of the control group,and this difference was also statistically significant(P<0.05).Furthermore,the overall therapeutic effect in the test group was 93.33%,which was markedly higher than 76.67%observed in the control group(P<0.05).[Conclusions]The therapeutic effect of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of CSR is remarkable.This approach has demonstrated efficacy in alleviating patient pain and improving the functionality of the cervical vertebrae,thereby warranting clinical promotion and application.展开更多
Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,con...Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,conventional MNs employ long needles(≥600μm),leading to pain and skin irritation.Moreover,it is critical to stably apply MNs against complex skin surfaces for uniform nanoscale drug delivery.Herein,a dually amplified transdermal patch(MN@EV/SC)is developed as the stem cell-derived EV delivery platform by hierarchically integrating an octopusinspired suction cup(SC)with short MNs(≤300μm).While leveraging the suction effect to induce nanoscale deformation of the stratum corneum,MN@EV/SC minimizes skin damage and enhances the adhesion of MNs,allowing EV to penetrate deeper into the dermis.When MNs of various lengths are applied to mouse skin,the short MNs can elicit comparable corticosterone release to chemical adhesives,whereas long MNs induce a prompt stress response.MN@EV/SC can achieve a remarkable penetration depth(290μm)for EV,compared to that of MN alone(111μm).Consequently,MN@EV/SC facilitates the revitalization of fibroblasts and enhances collagen synthesis in middle-aged mice.Overall,MN@EV/SC exhibits the potential for skin regeneration by modulating the dermal microenvironment and ensuring patient comfort.展开更多
OBJECTIVE:To update the current best evidence on the effectiveness and safety of cupping therapy in pain management.METHODS:The protocol of this systematic review was registered at PROSPERO(CRD42021261308).An updated ...OBJECTIVE:To update the current best evidence on the effectiveness and safety of cupping therapy in pain management.METHODS:The protocol of this systematic review was registered at PROSPERO(CRD42021261308).An updated literature searching in 7 databases was conducted from January 2014 to January 2023.Two authors extracted data and assessed the risk of bias independently.Statistical analysis was performed using RevMan 5.4.1 software(Cochrane Collaboration,London,UK).Meta-analysis with a random effect model was conducted when there was no serious statistical heterogeneity among trials(I^(2) ≤ 75%).Grading of Recommendations Assessment,Development,and Evaluation was also conducted to assess the quality of evidence.RESULTS:Seventy-two trials with 5720 participants were included.All included trials were assessed as having high risk of bias.The majority of the included trials reported the benefit of cupping plus other therapy or cupping alone on improving cure rate(average risk ratio more than 1.15) and reducing visual analogue scale [average mean difference(MD) reduction 0.16 to 7.0 cm],improving quality of life,quality of sleep or other symptoms related to pain condition.And there was low/very low quality evidence that the incidence of adverse events in the cupping groups were lower than that in the control groups.Although the heterogeneity between studies and the methodological quality of the study itself lead to the low evidence strength of the current conclusions,the results of this study are a valuable supplement to the founding of previous review.CONCLUSION:Cupping therapy alone or combined with other therapy was considered benefit in relieving pain,improving the quality of life,and increasing the cure rate of patients with pain conditions,though supported by the low quality of evidence.According to the limited evidence,cupping therapy seems to have less harm than drugs when treating pain conditions.展开更多
Introduction:Cupping therapy is an integrative and complementary medicine therapy that practiced worldwide by several civilizations for thousands of years.Cupping therapy is reported to be a relatively safe practice e...Introduction:Cupping therapy is an integrative and complementary medicine therapy that practiced worldwide by several civilizations for thousands of years.Cupping therapy is reported to be a relatively safe practice especially if performed by qualified therapists.Subconjunctival hemorrhage(SCH)is a common cause of eye redness and can be classified into traumatic and spontaneous.Case presentation:This case report discussed an adverse event related to wet cupping therapy.The patient developed SCH one day after performing cupping therapy.He was completely recovered after 2 weeks.This case report should increase the knowledge of cupping therapists regarding increasing safety of patient when performing wet cupping therapy on specific body parts especially,head,neck and cervical areas.Furthermore,it highlighted the importance of conducting research regarding the mechanical and physiological effects of cupping therapy.Conclusion:Adverse events related to cupping therapy should be reported with every patient.Cupping therapists should be aware of this possible mild adverse event.To the best of our knowledge,this is the first published adult case of SCH related to wet cupping therapy session.More studies are critically needed for evaluation of cupping therapy effects and adverse events especially when performed on head and neck.展开更多
Background As one of the most common musculoskeletal ailments,chronic nonspecific low-back pain(CNLBP)causes persistent disability and substantial medical expenses.Epidemiological evidence shows that the incidence rat...Background As one of the most common musculoskeletal ailments,chronic nonspecific low-back pain(CNLBP)causes persistent disability and substantial medical expenses.Epidemiological evidence shows that the incidence rate of CNLBP in young and middle-aged people who are demanded rapidly recovery and social contribution is rising.Recent guidelines indicate a reduced role for medicines in the management of CNLBP.Objective The present study investigates the short-term effects of cupping and scraping therapy using a medicated balm,compared to nonsteroidal anti-inflammatory drug(NSAID)with a capsaicin plaster,in the treatment of CNLBP.Design,setting,participants and interventions We designed a prospective multicenter randomized clinical trial enrolling patients from January 1,2022 to December 31,2022.A total of 156 patients with CNLBP were randomized into two parallel groups.Diclofenac sodium-sustained release tablets were administered orally to participants in the control group for one week while a capsaicin plaster was applied externally.Patients in the test group were treated with cupping and scraping using a medical device and medicated balm.Main outcome measures Primary outcome was pain recorded using the visual analogue scale(VAS).Two secondary outcomes were recorded using the Japanese Orthopedic Association low-back pain scale(JOA)and the traditional Chinese medicine(TCM)syndrome integral scale(TCMS)as assessment tools.Results Between baseline and postintervention,all changes in outcome metric scales were statistically significant(P<0.001).Compared to the control group,patients in the test group had a significantly greater treatment effect in all outcome variables,as indicated by lower VAS and TCMS scores and higher JOA scores,after the one-week intervention period(P<0.001).Further,according to the findings of multivariate linear regression analysis,the participants’pain(VAS score)was related to their marital status,age,smoking habits and body mass index.No adverse reactions were reported for any participants in this trial.Conclusion The effectiveness of TCM combined with the new physiotherapy tool is superior to that of NSAID combined with topical plasters,regarding to pain intensity,TCM symptoms and quality of life.The TCM plus physiotherapy also showed more stable and long-lasting therapeutic effects.展开更多
World Federation of Acupuncture-Moxibustion Societies(WFAS)Technical Benchmark of Acupuncture and Moxibustion:Cupping,developed under the leadership of Tianjin University of Traditional Chinese Medicine,was approved b...World Federation of Acupuncture-Moxibustion Societies(WFAS)Technical Benchmark of Acupuncture and Moxibustion:Cupping,developed under the leadership of Tianjin University of Traditional Chinese Medicine,was approved by WFAS.This technical benchmark was issued on October 9,2023,and implemented on December 31,2023.The main contents include the scope,normative references,terms and definitions,procedures and rules,and safety.This article focuses on the above contents,an outlook on the application,popularization,and update plan of this technical benchmark is proposed.展开更多
Background:The incidence of lumbar disc herniation(LDH)is notably high.Consensus among experts highlights non-surgical treatments as the primary therapeutic approach for LDH.Contemporary medicine frequently employs ph...Background:The incidence of lumbar disc herniation(LDH)is notably high.Consensus among experts highlights non-surgical treatments as the primary therapeutic approach for LDH.Contemporary medicine frequently employs pharmacotherapy and epidural injections in such treatments,which are associated with numerous adverse effects.Prolonged use can severely impair the liver and kidney functions of patients.Hence,the role of safe and effective traditional Chinese medicine techniques becomes pivotal.Among various traditional Chinese medicine approaches for treating LDH,fire dragon cupping,renowned for its remarkable efficacy,cost-effectiveness,and ease of application,is extensively utilised in clinical settings for managing LDH.Nonetheless,there is a scarcity of systematic and standardised evidence from evidence-based medicine studies.Therefore,conducting a meta-analysis is imperative.Methods:A comprehensive computerised search was conducted in databases including China National Knowledge Infrastructure,WanFang Data,VIP,China Biology Medicine disc,PubMed,EMbase,The Cochrane Library,Web of Science,and CINAHL.The search aimed to gather randomised controlled trials on fire dragon cupping therapy for LDH,spanning from the inception of these databases until December 2023.Two researchers independently screened the literature according to inclusion and exclusion criteria,extracted data,and assessed the methodological quality of the studies included,utilising RevMan 5.3 software for meta-analysis.Results:The results show that the fire dragon cupping therapy group had better clinical effectiveness(relative risk=1.23,95%confidence interval(CI)(1.14,1.33),P<0.00001),less pain(standardized mean difference=–1.33,95%CI(–1.49,–1.16),P<0.00001),and some improvement in lumbar function(Japanese Orthopaedic Association scores:mean difference=3.37,95%CI(2.31,4.43),P<0.00001.Conclusion:The fire dragon cupping therapy significantly alleviates LDH,warranting its extensive application.However,considering the limitations in the number and quality of studies included,the aforementioned conclusion necessitates further validation through more high-quality research.展开更多
[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were r...[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were randomly divided into three groups:lotus nee-dle cupping therapy group,TCM surrounding acupuncture group and gabapentin group.Venous blood and acupoint blood were collected at 0,21 and 42 d of treatment,and the expression levels of 5-HT,SP and CGRPinflammatory mediators were detected before and after treatment.The changes of VAS scores before,during and after treatment and the clinical efficacy were observed.[Results]The total effective rate of the lotus needle cupping group was 87.50%,which was better than that of the TCM acupuncture group(81.25%)and the gabapentin group(62.50%);after treatment,the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment,and the decrease was more significant in the treatment group(P<0.05).[Conclusions]The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN,and its mechanism is to reduce the release of inflammatory media-tors,reduce hyperalgesia,relieve pain and improve the quality of life of patients.展开更多
Objective To observe influence of kinetic needling on functional restoration of upper limbs of patients with apoplexy-induced shoulder-hand syndrome. Methods Ninety patients were randomly divided into an observation g...Objective To observe influence of kinetic needling on functional restoration of upper limbs of patients with apoplexy-induced shoulder-hand syndrome. Methods Ninety patients were randomly divided into an observation group （45 cases） and a control group （45 cases）. Basic treatments selected according to corresponding stroke units were applied to both groups. Besides, scalp acupuncture at Dingnie Qianxiexian （MS 6, 顶颞前斜线）, Dingnie Houxiexian （MS 6, 顶颞前斜线） and Dingzhongxian （NS 5, 顶中线）, was applied in the treatment group. In the observation group, active and passive movement was carried out during the process of scalp acupuncture, and then needling plus bloodletting puncturing and cupping was applied. In the control group, only needling plus blood-letting puncturing and cupping was given. Therapeutic effects, pain scoring obtained by visual analogue scales （VAS）, FugI-Meyer and FugI-Meyer＇s scoring reflecting moving functions of upper limbs were made after 4 courses of treatments in both groups. Results The total effective rate was 95.5% and 91.1% in the observation group and control group, respectively, showing superiority of the former to the latter （P〈0.05）. After treatment, VAS scores were all obviously reduced in both groups （P〈0.01）, and the reduction in the former was significantly more than that in the latter （P〈0.01）. Moving functions of upper limbs shown by Fugl-Meyer＇s scoring were improved after 2 courses of treatment in both groups （P〈0.01）. The improvement was more obvious after 4 courses of treatment than that after 2 courses of treatment in both groups （P〈0.05）. After 4 courses of treatment, moving functions shown by FugI-Meyer＇s scoring were more remarkably improved in the observation group than those in the control group（t=3.9, P〈0.01）. Conclusion Both kinetic needling combined with needling plus blood-letting puncturing and cupping and simple needling plus blood-letting puncturing and cupping are effective in treating shoulder-hand syndrome after apoplexy, and the former is better than the latter.展开更多
Objective To observe the effects of cupping on blood flow under different skins of back in healthy human. Methods With meridian-cupping dredging apparatus to set cupping pressure at -0.04 MPa, cupping was applied at D...Objective To observe the effects of cupping on blood flow under different skins of back in healthy human. Methods With meridian-cupping dredging apparatus to set cupping pressure at -0.04 MPa, cupping was applied at Dhzhui （大椎 GV 14） and bilateral Dazhu （大杼 BL 11） for 10 min in healthy subject. Blood flow monitoring video system of laser speckle was used to record blood flow of GV 14, Shenzhu （身柱 GV 12）, bilateral Feishu （肺俞 BL 13） and Xinshu （心俞 BL 15） before cupping therapy, immediate time of cupping removal and 5 min, 10 rain, 15 min, 20 min, 25 rain and 30 rain after cupping removal. Results Compared before cupping therapy, the blood flow of GV 14, GV 12 and bilateral BL 13 was obviously increased at immediate time of cupping removal （all P〈0.05）. Compared with immediate time of cupping removal, the blood flow of GV 14 at each time point after 20 rain of cupping removal, GV 12 at 10 min and 15 min after cupping removal, bilateral BL 13 at each time point after cupping removal was all obviously decreased （all P〈0.05）. The difference of blood flow of Shendao （神道 GV 11） and bilateral BL 15 before and after cupping therapy was not significantly different （all P〉0.05）. Conclusion The cupping therapy could adjust skin blood flow, which is more obvious near the cupping area.展开更多
Objective To preliminarily observe the effects of cupping on localized skin temperature of patients with back pain.Methods A total of 43 patients with back pain were included in this study.They were treated with mediu...Objective To preliminarily observe the effects of cupping on localized skin temperature of patients with back pain.Methods A total of 43 patients with back pain were included in this study.They were treated with medium-sized cups with a volume of 260 mL The randomly selected Xinshu（心俞 BL 15）on one side（37 cases） was given cupping treatment while that on the other side as the control.And Shenshu（肾俞 BL 23）（6 cases） was treated in the same way.The thermal infrared imager was used to record the changes in localized skin temperature before and after cupping（for 10 minutes）,and then comparison was made with that of the control side.Results After cupping,the localized skin temperature fell and then rose.When the cup was removed after retaining for 10 minutes,the localized skin temperature was（0.4±0.9） ℃（P=0.004） lower than that before cupping;10 minutes after cupping off,the localized skin temperature was（0.4±1.1） ℃（P=0.016） higher than that before cupping while（0.8±0.9） ℃ higher than that when cupping off.The skin surface temperature on the control side declined steadily.Conclusion After cupping treatment,the localized skin temperature fell and then rose while that of the control side declined steadily.It might be related to therapeutic effects.展开更多
Objective To observe the clinical effects of simple obesity treated with needling and quick cupping therapy at the selected eight points around umbilicus. Methods Ninety-five cases were randomly allocated into an obse...Objective To observe the clinical effects of simple obesity treated with needling and quick cupping therapy at the selected eight points around umbilicus. Methods Ninety-five cases were randomly allocated into an observation group and a control group. In observation group （n=50） patients were treated with acupuncture and quick cupping therapy at the selected eight points around umbilicus, namely Huaroumen （滑肉门 ST 24）, Tianshu （天枢 ST 25）,Wailing （外陵 ST 26）,Shuifen （水分 CV 9）, and Yinjiao（阴交 CV 7）.In control group （n=45） patients were advised to take Sibutramine, an oral administration to suppress appetite. Relevant data concerning one＇s weight, body mass index （BMI）, waist hip ratio （WHR） and distribution rate of body fat （F%） before treatment and after eight weeks＇ of treatment were collected to observe the effects. Results The total effective rate was 98.0%（49/50） in the observation group and 97.8%（44/45） in the control group. There was no significant difference on body weight and BMI between the two groups （P〉0.05）, however the therapeutic effects on WHR and F% in the observation group were more satisfactory than those of the control group （P〈0.05）. Conclusion Acupuncture and quick cupping therapy at the selected eight points around umbilicus have a good therapeutic effect on simple obesity, moreover acupuncture and quick cupping therapy can greatly improve the condition of WHR and F% for obesity patients, which is also safe and without any side effect.展开更多
Objective To observe the application of acupuncture at distal points combined with medicated cupping on the affected parts in the treatment of temporomandibular disorders（TMD） and to evaluate its effectiveness. Meth...Objective To observe the application of acupuncture at distal points combined with medicated cupping on the affected parts in the treatment of temporomandibular disorders（TMD） and to evaluate its effectiveness. Methods A total of 120 patients with TMD were randomly divided into two groups according to the random number table and random number remainder method. Sixty-two patients in acupuncture combined with cupping group（group A） were treated with acupuncture at Hég（合谷 LI 4） and Tàichōng（太冲 LR 3） combined with medicated cupping on the affected parts with Sānqī（三七 Radix et Rhizoma Notoginseng） and Báizh（白芷 Radix Angelicae Dahuricae）. Fifty-eight patients in cupping group（group B） were just treated with medicated cupping. Patients were treated for 30 min each time, once daily, and 10 times were considered as one course of treatment. After one course of treatment, the therapeutic effect was evaluated. Before and after treatment, craniomandihular index（CMI）, dysfunction index（DI）, palpation index（Pl） and changes in pain degree（VAS score） were compared. Results Before and after treatment, CMI in group A were 0.27±0.02 and 0.04±0.01, respectively, and in group B were 0.29±0.02 and 0.06±0.01, respectively; PI in group A were 0.19±0.01 and 0.05±0.03, respectively, and in group B were 0.18±0.02 and 0.11±0.02, respectively; DI in group A were 0.33±0.04 and 0.06±0.02, respectively, and in group B were 0.34±0.05 and 0.11±0.04, respectively; VAS in group A were 5.39±0.24 and 2.13±0.47, respectively, and in group B were 5.70±0.31 and 3.97±0.26, respectively. After treatment, CMI, DI, PI and VAS in both groups significantly decreased when compared with those before treatment（all P0.01）, and the indices in group A were significantly lower than that in group B after treatment（all P0.05）, indicating that the difference was significant. Conclusion The therapeutic effect of acupuncture at distal points combined with cupping at adjacent points in treatment of TMD is superior to that of single medicated cupping therapy.展开更多
Objective To compare the differences of therapeutic effect of chronic fatigue syndrome （CFS） treated with the combined therapy of Panlongci （coiling dragon needling） and cupping on back and the western medicine th...Objective To compare the differences of therapeutic effect of chronic fatigue syndrome （CFS） treated with the combined therapy of Panlongci （coiling dragon needling） and cupping on back and the western medicine therapy with prednisone. Methods Seventy-two cases were randomly divided into 2 groups of acupuncture-cupping group （37 cases） and prednisone group （35 cases）. In acupuncture-cupping group, Jiaji points （夹脊 EX-B 2） of the level of T1–L5 were applied with coiling dragon needling once a day, combining with moving cupping on back once every two days. In prednisone group, prednisone tablets of 10 mg were orally taken at 8：00 am everyday. Seven days were counted as one treatment course, and 2 courses were carried on totally. FS-14 scale and BELL’s CFS integral table were applied to evaluate the fatigue degree of patients before and after the treatment, and the therapeutic effects of both groups were compared. Results After one course of treatment, the BELL’s scores of both groups were obviously improved （both P0.01）, but there was no significant difference between the 2 groups （P0.05）; after 2 courses of treatment, the BELL’s score in acupuncture-cupping group improved more obviously than that of the prednisone group （P0.05）, and the total effective rate of 91.9% （34/37） in acupuncture-cupping group was superior to that of 71.4% （25/35） in prednisone group （P0.05）. Conclusion The therapeutic effect of chronic fatigue syndrome treated with coiling dragon needling and moving cupping on back is positive, which is superior to that of prednisone with oral administration.展开更多
Objective To observe the clinical efficacy of treating postherpetic neuralgia （PHN） by combining floating-acupuncture laser with cupping following collateral bloodletting, and to analyze its mechanism. Method One hu...Objective To observe the clinical efficacy of treating postherpetic neuralgia （PHN） by combining floating-acupuncture laser with cupping following collateral bloodletting, and to analyze its mechanism. Method One hundred and thirty cases of PHN were randomly divided into a floating-acupuncture laser with cupping following collateral bloodletting group （group A） and an electroacupuncture group （group B） based on the treatment sequence and according to the random number table, with 65 cases in each group. In the group B, G-6805 electroacupuncture apparatus was adopted after the arrival of qi through even reinforcing and reducing （even method） in such acupoints as Hegu （合俗 LI 4）, Taihong （太冲 LR 3）, Zhigou （支沟 TE 6）, Quchi （ 曲池 LI 11） and Zusanli （足三里 ST 36）; in the group A, the treatment combining floatingacupuncture laser with cupping following collateral bloodletting was adopted, and the score of VAS and clinical efficacy before and after treatment in the two groups were compared. Result The differences of VAS scores of the two groups between the time points of after one course of treatment, after the entire treatment, follow up visit three months after the treatment and before treatment were statistically significant （all P〈0.05）. The rate of significant efficiency and total effective rate in the group A were respectively 37.8% and 98.5% （64/65）, and 11.2% and 78.5% （52/65） in the group B. The difference between the two groups was statistically significant after Ridit analysis （P〈0.05）. Conclusion The efficacy of treating PHN by combining floating-acupuncture laser with cupping following collateral bloodletting was significant.展开更多
Objective To explore the clinical efficacy of acupuncture combined with vesiculating cupping in treatment of rheumatoid arthritis（RA）. Methods A total of 110 patients with RA were randomly divided into an acupunctur...Objective To explore the clinical efficacy of acupuncture combined with vesiculating cupping in treatment of rheumatoid arthritis（RA）. Methods A total of 110 patients with RA were randomly divided into an acupuncture combined with vesiculating cupping group（group A） and an acupuncture combined with non-vesiculating cupping group（group B）. Treatment was conducted once a day in two groups, and ten days were considered as one course of treatment. The total effective rate was observed after treatment for three courses. Results The difference in cured and markable effective rate of group A and group B was obviously significant [81.82%（45/55） vs 18.18%（10/55）, P〈0.01], the difference in total effective rate of group A and group B was significant [96.36%（53/55） vs 69.09%（38/55）, P〈0.05], indicating that the efficacy in group A was significantly superior to that of group B. Conclusion Acupurcture combined with vesiculating cupping therapy achieves more satisfactory efficacy on RA compared with acupuncture combined with nonvesiculating cupping therapy.展开更多
Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods S...Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods Sixty-five patients of neck type of cervical spondylosis were selected and treated with blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point once every two or three days,three times constituted one course and two successive courses were given,then the clinical effect was evaluated.Results The curative rate was 69.2%（45/65）,and the total effective rate was 92.3%（60/65）.Conclusion Blood-letting puncture and cupping at Dong＇s Chōngxiāo（冲霄 Extra） point can be used to treat neck type of cervical spondylosis with simple manipulation and obvious efficacy.展开更多
BACKGROUND Wet cupping (WC) is a traditional therapy of skin suction-assisted bloodlettingthat is widely used in modern alternative medicine in Asia and the Middle East.Herein, we report the case of a male who present...BACKGROUND Wet cupping (WC) is a traditional therapy of skin suction-assisted bloodlettingthat is widely used in modern alternative medicine in Asia and the Middle East.Herein, we report the case of a male who presented with ST-elevation myocardialinfarction (STEMI) and life-threatening anemia and underwent excessive WC.CASE SUMMARY A 55-year-old male presented with chest pain (30 min) and dyspnea (3 wk). Hisinitial electrocardiogram suggested STEMI in the anterior wall. Furthermore, hislaboratory results showed severe anemia with a hemoglobin level of 4.1 g/dL. Ofnote, the patient underwent regular WC therapy for chronic back pain, which hehad recently intensified. His WC practice resulted in life-threatening anemia andeventually STEMI. Percutaneous coronary intervention in the left anteriordescending artery was performed to treat the STEMI. His dyspnea dramaticallyimproved after the transfusion, and his hemoglobin level returned to 14.8 g/dLwithin 2 mo after discharge. He has been uneventful for the last seven years offollow-up.CONCLUSION The current case demonstrates that excessive WC without adequate medicalmonitoring can result in severe anemia, which can further develop into STEMI.展开更多
Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and...Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy.展开更多
Blistering cupping therapy, as a new type of cupping therapy, has attracted more and more attention of clinical doctor and scholars in home and abroad. Blistering cupping therapy achieves better effects through the fo...Blistering cupping therapy, as a new type of cupping therapy, has attracted more and more attention of clinical doctor and scholars in home and abroad. Blistering cupping therapy achieves better effects through the formation of blistering fluid after suction. However, it is still controversial whether cupping induced blisters are beneficial to recovery of diseases, and the mechanism is still not completely clear. Here on the basis of the traditional cupping method, we aimed to identify the mechanism of blistering cupping from the levels of biomechanics and molecular biology. The negative pressure attraction induced by cupping suck should be of value in increasing pain threshold and relieving pain as well as improving the blood circulation and metabolism. Furthermore, the blistering fluid induced by cupping was the inflammatory substance actually that discharged through the superficial lymphatic vessels, including immunoglobulin, lysozyme, erythrocytes, etc. which could cause the autogenetic inflammatory reaction of selected cupping area, and further activated certain immune pathways including anti-oxidation, anti-apoptosis, tissue repairing and metabolic regulation. Besides, the formation of scar induced by blistering cupping was not only the result of excessive inflammatory response, but also involved in mobilizing the immune response.展开更多
基金Supported by Project of Science and Technology Department of Inner Mongolia Autonomous Region(2019GG125).
文摘[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patients diagnosed with CSR who received treatment at the International Mongolian Hospital of Inner Mongolia between October 2021 and October 2022 were selected and randomly divided into two groups:A test group and a control group,with 60 patients in each group.The patients in the test group received Mongolian medicine silver needle combined with cupping and bloodletting therapy,following the principles of syndrome differentiation in Mongolian medicine.In contrast,the patients in the control group received only the Mongolian medicine silver needle therapy.After treatment,the Mongolian medicine syndrome scores,visual analogue scale(VAS)scores,and total clinical therapeutic effects in the two groups of patients were compared both prior to and following the treatment.[Results]The improvement in VAS and Mongolian medicine syndrome scores in the test group was greater than that in the control group,with a statistically significant difference(P<0.05).The scores of the test group surpassed those of the control group,and this difference was also statistically significant(P<0.05).Furthermore,the overall therapeutic effect in the test group was 93.33%,which was markedly higher than 76.67%observed in the control group(P<0.05).[Conclusions]The therapeutic effect of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of CSR is remarkable.This approach has demonstrated efficacy in alleviating patient pain and improving the functionality of the cervical vertebrae,thereby warranting clinical promotion and application.
基金supported by National Research Foundation of Korea(NRF)grants funded by the Korean government(MSIT)(No.RS-2023-00256265,RS-2024-00352352,RS-2024-00405818)the Korean Fund for Regenerative Medicine(KFRM)grant funded by the Korea government(the Ministry of Science and ICT,the Ministry of Health&Welfare).(No.25A0102L1)support from the Market-led K-sensor technology program(RS-2022-00154781,Development of large-area wafer-level flexible/stretchable hybrid sensor platform technology for form factor-free highly integrated convergence sensor),funded By the Ministry of Trade,Industry&Energy(MOTIE,Korea).
文摘Microneedles(MNs)have been extensively investigated for transdermal delivery of large-sized drugs,including proteins,nucleic acids,and even extracellular vesicles(EVs).However,for their sufficient skin penetration,conventional MNs employ long needles(≥600μm),leading to pain and skin irritation.Moreover,it is critical to stably apply MNs against complex skin surfaces for uniform nanoscale drug delivery.Herein,a dually amplified transdermal patch(MN@EV/SC)is developed as the stem cell-derived EV delivery platform by hierarchically integrating an octopusinspired suction cup(SC)with short MNs(≤300μm).While leveraging the suction effect to induce nanoscale deformation of the stratum corneum,MN@EV/SC minimizes skin damage and enhances the adhesion of MNs,allowing EV to penetrate deeper into the dermis.When MNs of various lengths are applied to mouse skin,the short MNs can elicit comparable corticosterone release to chemical adhesives,whereas long MNs induce a prompt stress response.MN@EV/SC can achieve a remarkable penetration depth(290μm)for EV,compared to that of MN alone(111μm).Consequently,MN@EV/SC facilitates the revitalization of fibroblasts and enhances collagen synthesis in middle-aged mice.Overall,MN@EV/SC exhibits the potential for skin regeneration by modulating the dermal microenvironment and ensuring patient comfort.
基金National Natural Science Foundation of China Project:Research on the Correlation between Traditional Chinese Medicine Constitution,Cupping Marks Color,and Clinical Efficacy Based on Regression Models (No.81804000)。
文摘OBJECTIVE:To update the current best evidence on the effectiveness and safety of cupping therapy in pain management.METHODS:The protocol of this systematic review was registered at PROSPERO(CRD42021261308).An updated literature searching in 7 databases was conducted from January 2014 to January 2023.Two authors extracted data and assessed the risk of bias independently.Statistical analysis was performed using RevMan 5.4.1 software(Cochrane Collaboration,London,UK).Meta-analysis with a random effect model was conducted when there was no serious statistical heterogeneity among trials(I^(2) ≤ 75%).Grading of Recommendations Assessment,Development,and Evaluation was also conducted to assess the quality of evidence.RESULTS:Seventy-two trials with 5720 participants were included.All included trials were assessed as having high risk of bias.The majority of the included trials reported the benefit of cupping plus other therapy or cupping alone on improving cure rate(average risk ratio more than 1.15) and reducing visual analogue scale [average mean difference(MD) reduction 0.16 to 7.0 cm],improving quality of life,quality of sleep or other symptoms related to pain condition.And there was low/very low quality evidence that the incidence of adverse events in the cupping groups were lower than that in the control groups.Although the heterogeneity between studies and the methodological quality of the study itself lead to the low evidence strength of the current conclusions,the results of this study are a valuable supplement to the founding of previous review.CONCLUSION:Cupping therapy alone or combined with other therapy was considered benefit in relieving pain,improving the quality of life,and increasing the cure rate of patients with pain conditions,though supported by the low quality of evidence.According to the limited evidence,cupping therapy seems to have less harm than drugs when treating pain conditions.
文摘Introduction:Cupping therapy is an integrative and complementary medicine therapy that practiced worldwide by several civilizations for thousands of years.Cupping therapy is reported to be a relatively safe practice especially if performed by qualified therapists.Subconjunctival hemorrhage(SCH)is a common cause of eye redness and can be classified into traumatic and spontaneous.Case presentation:This case report discussed an adverse event related to wet cupping therapy.The patient developed SCH one day after performing cupping therapy.He was completely recovered after 2 weeks.This case report should increase the knowledge of cupping therapists regarding increasing safety of patient when performing wet cupping therapy on specific body parts especially,head,neck and cervical areas.Furthermore,it highlighted the importance of conducting research regarding the mechanical and physiological effects of cupping therapy.Conclusion:Adverse events related to cupping therapy should be reported with every patient.Cupping therapists should be aware of this possible mild adverse event.To the best of our knowledge,this is the first published adult case of SCH related to wet cupping therapy session.More studies are critically needed for evaluation of cupping therapy effects and adverse events especially when performed on head and neck.
基金supported by the 13th Five-Year Army Key Discipline Construction Project(No.2020SZ06-17).
文摘Background As one of the most common musculoskeletal ailments,chronic nonspecific low-back pain(CNLBP)causes persistent disability and substantial medical expenses.Epidemiological evidence shows that the incidence rate of CNLBP in young and middle-aged people who are demanded rapidly recovery and social contribution is rising.Recent guidelines indicate a reduced role for medicines in the management of CNLBP.Objective The present study investigates the short-term effects of cupping and scraping therapy using a medicated balm,compared to nonsteroidal anti-inflammatory drug(NSAID)with a capsaicin plaster,in the treatment of CNLBP.Design,setting,participants and interventions We designed a prospective multicenter randomized clinical trial enrolling patients from January 1,2022 to December 31,2022.A total of 156 patients with CNLBP were randomized into two parallel groups.Diclofenac sodium-sustained release tablets were administered orally to participants in the control group for one week while a capsaicin plaster was applied externally.Patients in the test group were treated with cupping and scraping using a medical device and medicated balm.Main outcome measures Primary outcome was pain recorded using the visual analogue scale(VAS).Two secondary outcomes were recorded using the Japanese Orthopedic Association low-back pain scale(JOA)and the traditional Chinese medicine(TCM)syndrome integral scale(TCMS)as assessment tools.Results Between baseline and postintervention,all changes in outcome metric scales were statistically significant(P<0.001).Compared to the control group,patients in the test group had a significantly greater treatment effect in all outcome variables,as indicated by lower VAS and TCMS scores and higher JOA scores,after the one-week intervention period(P<0.001).Further,according to the findings of multivariate linear regression analysis,the participants’pain(VAS score)was related to their marital status,age,smoking habits and body mass index.No adverse reactions were reported for any participants in this trial.Conclusion The effectiveness of TCM combined with the new physiotherapy tool is superior to that of NSAID combined with topical plasters,regarding to pain intensity,TCM symptoms and quality of life.The TCM plus physiotherapy also showed more stable and long-lasting therapeutic effects.
基金Supported by National Key R&D Program of China:2019YFC1712200-2019YFC1712204。
文摘World Federation of Acupuncture-Moxibustion Societies(WFAS)Technical Benchmark of Acupuncture and Moxibustion:Cupping,developed under the leadership of Tianjin University of Traditional Chinese Medicine,was approved by WFAS.This technical benchmark was issued on October 9,2023,and implemented on December 31,2023.The main contents include the scope,normative references,terms and definitions,procedures and rules,and safety.This article focuses on the above contents,an outlook on the application,popularization,and update plan of this technical benchmark is proposed.
基金supported by the 2022 study on the effectiveness of Fire Dragon Cupping in treating cold-dampness obstructive type shoulder stiffness,funded by the Bao'an District Healthcare Research Project in Shenzhen(Shen Bao Ke[2023]No.13,Project No.2022JD237)2023 study on the therapeutic observation and mechanism exploration of Fire Dragon Cupping in cold-dampness obstructive type acute gout,funded by the Guangdong Provincial Administration of Traditional Chinese Medicine(Yue Zhong Yi Han[2023]No.205,Project No.20242077)+1 种基金National Clinical Key Specialty(Traditional Chinese Medicine)Construction Project(2013-239)Sanming Project of Medicine in Shenzhen(No.SZZYSM202206014).
文摘Background:The incidence of lumbar disc herniation(LDH)is notably high.Consensus among experts highlights non-surgical treatments as the primary therapeutic approach for LDH.Contemporary medicine frequently employs pharmacotherapy and epidural injections in such treatments,which are associated with numerous adverse effects.Prolonged use can severely impair the liver and kidney functions of patients.Hence,the role of safe and effective traditional Chinese medicine techniques becomes pivotal.Among various traditional Chinese medicine approaches for treating LDH,fire dragon cupping,renowned for its remarkable efficacy,cost-effectiveness,and ease of application,is extensively utilised in clinical settings for managing LDH.Nonetheless,there is a scarcity of systematic and standardised evidence from evidence-based medicine studies.Therefore,conducting a meta-analysis is imperative.Methods:A comprehensive computerised search was conducted in databases including China National Knowledge Infrastructure,WanFang Data,VIP,China Biology Medicine disc,PubMed,EMbase,The Cochrane Library,Web of Science,and CINAHL.The search aimed to gather randomised controlled trials on fire dragon cupping therapy for LDH,spanning from the inception of these databases until December 2023.Two researchers independently screened the literature according to inclusion and exclusion criteria,extracted data,and assessed the methodological quality of the studies included,utilising RevMan 5.3 software for meta-analysis.Results:The results show that the fire dragon cupping therapy group had better clinical effectiveness(relative risk=1.23,95%confidence interval(CI)(1.14,1.33),P<0.00001),less pain(standardized mean difference=–1.33,95%CI(–1.49,–1.16),P<0.00001),and some improvement in lumbar function(Japanese Orthopaedic Association scores:mean difference=3.37,95%CI(2.31,4.43),P<0.00001.Conclusion:The fire dragon cupping therapy significantly alleviates LDH,warranting its extensive application.However,considering the limitations in the number and quality of studies included,the aforementioned conclusion necessitates further validation through more high-quality research.
基金Supported by Guangxi Natural Science Foundation(2018GXNSFAA050141)Basic AbilityImprovement Project for Young and Middle-aged Teachers in Guangxi Zhuang Autonomous Region(2019KY0336)Guangxi Famous Tradi-tional Chinese Medicine Inheritance Studio-Qin Zujie[GuiZhongYiYaoKeJiao-Fa(2021)No.6].
文摘[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were randomly divided into three groups:lotus nee-dle cupping therapy group,TCM surrounding acupuncture group and gabapentin group.Venous blood and acupoint blood were collected at 0,21 and 42 d of treatment,and the expression levels of 5-HT,SP and CGRPinflammatory mediators were detected before and after treatment.The changes of VAS scores before,during and after treatment and the clinical efficacy were observed.[Results]The total effective rate of the lotus needle cupping group was 87.50%,which was better than that of the TCM acupuncture group(81.25%)and the gabapentin group(62.50%);after treatment,the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment,and the decrease was more significant in the treatment group(P<0.05).[Conclusions]The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN,and its mechanism is to reduce the release of inflammatory media-tors,reduce hyperalgesia,relieve pain and improve the quality of life of patients.
文摘Objective To observe influence of kinetic needling on functional restoration of upper limbs of patients with apoplexy-induced shoulder-hand syndrome. Methods Ninety patients were randomly divided into an observation group （45 cases） and a control group （45 cases）. Basic treatments selected according to corresponding stroke units were applied to both groups. Besides, scalp acupuncture at Dingnie Qianxiexian （MS 6, 顶颞前斜线）, Dingnie Houxiexian （MS 6, 顶颞前斜线） and Dingzhongxian （NS 5, 顶中线）, was applied in the treatment group. In the observation group, active and passive movement was carried out during the process of scalp acupuncture, and then needling plus bloodletting puncturing and cupping was applied. In the control group, only needling plus blood-letting puncturing and cupping was given. Therapeutic effects, pain scoring obtained by visual analogue scales （VAS）, FugI-Meyer and FugI-Meyer＇s scoring reflecting moving functions of upper limbs were made after 4 courses of treatments in both groups. Results The total effective rate was 95.5% and 91.1% in the observation group and control group, respectively, showing superiority of the former to the latter （P〈0.05）. After treatment, VAS scores were all obviously reduced in both groups （P〈0.01）, and the reduction in the former was significantly more than that in the latter （P〈0.01）. Moving functions of upper limbs shown by Fugl-Meyer＇s scoring were improved after 2 courses of treatment in both groups （P〈0.01）. The improvement was more obvious after 4 courses of treatment than that after 2 courses of treatment in both groups （P〈0.05）. After 4 courses of treatment, moving functions shown by FugI-Meyer＇s scoring were more remarkably improved in the observation group than those in the control group（t=3.9, P〈0.01）. Conclusion Both kinetic needling combined with needling plus blood-letting puncturing and cupping and simple needling plus blood-letting puncturing and cupping are effective in treating shoulder-hand syndrome after apoplexy, and the former is better than the latter.
基金Supported by Natural Science Foundaion of China in 2012(No.81273673)
文摘Objective To observe the effects of cupping on blood flow under different skins of back in healthy human. Methods With meridian-cupping dredging apparatus to set cupping pressure at -0.04 MPa, cupping was applied at Dhzhui （大椎 GV 14） and bilateral Dazhu （大杼 BL 11） for 10 min in healthy subject. Blood flow monitoring video system of laser speckle was used to record blood flow of GV 14, Shenzhu （身柱 GV 12）, bilateral Feishu （肺俞 BL 13） and Xinshu （心俞 BL 15） before cupping therapy, immediate time of cupping removal and 5 min, 10 rain, 15 min, 20 min, 25 rain and 30 rain after cupping removal. Results Compared before cupping therapy, the blood flow of GV 14, GV 12 and bilateral BL 13 was obviously increased at immediate time of cupping removal （all P〈0.05）. Compared with immediate time of cupping removal, the blood flow of GV 14 at each time point after 20 rain of cupping removal, GV 12 at 10 min and 15 min after cupping removal, bilateral BL 13 at each time point after cupping removal was all obviously decreased （all P〈0.05）. The difference of blood flow of Shendao （神道 GV 11） and bilateral BL 15 before and after cupping therapy was not significantly different （all P〉0.05）. Conclusion The cupping therapy could adjust skin blood flow, which is more obvious near the cupping area.
文摘Objective To preliminarily observe the effects of cupping on localized skin temperature of patients with back pain.Methods A total of 43 patients with back pain were included in this study.They were treated with medium-sized cups with a volume of 260 mL The randomly selected Xinshu（心俞 BL 15）on one side（37 cases） was given cupping treatment while that on the other side as the control.And Shenshu（肾俞 BL 23）（6 cases） was treated in the same way.The thermal infrared imager was used to record the changes in localized skin temperature before and after cupping（for 10 minutes）,and then comparison was made with that of the control side.Results After cupping,the localized skin temperature fell and then rose.When the cup was removed after retaining for 10 minutes,the localized skin temperature was（0.4±0.9） ℃（P=0.004） lower than that before cupping;10 minutes after cupping off,the localized skin temperature was（0.4±1.1） ℃（P=0.016） higher than that before cupping while（0.8±0.9） ℃ higher than that when cupping off.The skin surface temperature on the control side declined steadily.Conclusion After cupping treatment,the localized skin temperature fell and then rose while that of the control side declined steadily.It might be related to therapeutic effects.
文摘Objective To observe the clinical effects of simple obesity treated with needling and quick cupping therapy at the selected eight points around umbilicus. Methods Ninety-five cases were randomly allocated into an observation group and a control group. In observation group （n=50） patients were treated with acupuncture and quick cupping therapy at the selected eight points around umbilicus, namely Huaroumen （滑肉门 ST 24）, Tianshu （天枢 ST 25）,Wailing （外陵 ST 26）,Shuifen （水分 CV 9）, and Yinjiao（阴交 CV 7）.In control group （n=45） patients were advised to take Sibutramine, an oral administration to suppress appetite. Relevant data concerning one＇s weight, body mass index （BMI）, waist hip ratio （WHR） and distribution rate of body fat （F%） before treatment and after eight weeks＇ of treatment were collected to observe the effects. Results The total effective rate was 98.0%（49/50） in the observation group and 97.8%（44/45） in the control group. There was no significant difference on body weight and BMI between the two groups （P〉0.05）, however the therapeutic effects on WHR and F% in the observation group were more satisfactory than those of the control group （P〈0.05）. Conclusion Acupuncture and quick cupping therapy at the selected eight points around umbilicus have a good therapeutic effect on simple obesity, moreover acupuncture and quick cupping therapy can greatly improve the condition of WHR and F% for obesity patients, which is also safe and without any side effect.
文摘Objective To observe the application of acupuncture at distal points combined with medicated cupping on the affected parts in the treatment of temporomandibular disorders（TMD） and to evaluate its effectiveness. Methods A total of 120 patients with TMD were randomly divided into two groups according to the random number table and random number remainder method. Sixty-two patients in acupuncture combined with cupping group（group A） were treated with acupuncture at Hég（合谷 LI 4） and Tàichōng（太冲 LR 3） combined with medicated cupping on the affected parts with Sānqī（三七 Radix et Rhizoma Notoginseng） and Báizh（白芷 Radix Angelicae Dahuricae）. Fifty-eight patients in cupping group（group B） were just treated with medicated cupping. Patients were treated for 30 min each time, once daily, and 10 times were considered as one course of treatment. After one course of treatment, the therapeutic effect was evaluated. Before and after treatment, craniomandihular index（CMI）, dysfunction index（DI）, palpation index（Pl） and changes in pain degree（VAS score） were compared. Results Before and after treatment, CMI in group A were 0.27±0.02 and 0.04±0.01, respectively, and in group B were 0.29±0.02 and 0.06±0.01, respectively; PI in group A were 0.19±0.01 and 0.05±0.03, respectively, and in group B were 0.18±0.02 and 0.11±0.02, respectively; DI in group A were 0.33±0.04 and 0.06±0.02, respectively, and in group B were 0.34±0.05 and 0.11±0.04, respectively; VAS in group A were 5.39±0.24 and 2.13±0.47, respectively, and in group B were 5.70±0.31 and 3.97±0.26, respectively. After treatment, CMI, DI, PI and VAS in both groups significantly decreased when compared with those before treatment（all P0.01）, and the indices in group A were significantly lower than that in group B after treatment（all P0.05）, indicating that the difference was significant. Conclusion The therapeutic effect of acupuncture at distal points combined with cupping at adjacent points in treatment of TMD is superior to that of single medicated cupping therapy.
文摘Objective To compare the differences of therapeutic effect of chronic fatigue syndrome （CFS） treated with the combined therapy of Panlongci （coiling dragon needling） and cupping on back and the western medicine therapy with prednisone. Methods Seventy-two cases were randomly divided into 2 groups of acupuncture-cupping group （37 cases） and prednisone group （35 cases）. In acupuncture-cupping group, Jiaji points （夹脊 EX-B 2） of the level of T1–L5 were applied with coiling dragon needling once a day, combining with moving cupping on back once every two days. In prednisone group, prednisone tablets of 10 mg were orally taken at 8：00 am everyday. Seven days were counted as one treatment course, and 2 courses were carried on totally. FS-14 scale and BELL’s CFS integral table were applied to evaluate the fatigue degree of patients before and after the treatment, and the therapeutic effects of both groups were compared. Results After one course of treatment, the BELL’s scores of both groups were obviously improved （both P0.01）, but there was no significant difference between the 2 groups （P0.05）; after 2 courses of treatment, the BELL’s score in acupuncture-cupping group improved more obviously than that of the prednisone group （P0.05）, and the total effective rate of 91.9% （34/37） in acupuncture-cupping group was superior to that of 71.4% （25/35） in prednisone group （P0.05）. Conclusion The therapeutic effect of chronic fatigue syndrome treated with coiling dragon needling and moving cupping on back is positive, which is superior to that of prednisone with oral administration.
文摘Objective To observe the clinical efficacy of treating postherpetic neuralgia （PHN） by combining floating-acupuncture laser with cupping following collateral bloodletting, and to analyze its mechanism. Method One hundred and thirty cases of PHN were randomly divided into a floating-acupuncture laser with cupping following collateral bloodletting group （group A） and an electroacupuncture group （group B） based on the treatment sequence and according to the random number table, with 65 cases in each group. In the group B, G-6805 electroacupuncture apparatus was adopted after the arrival of qi through even reinforcing and reducing （even method） in such acupoints as Hegu （合俗 LI 4）, Taihong （太冲 LR 3）, Zhigou （支沟 TE 6）, Quchi （ 曲池 LI 11） and Zusanli （足三里 ST 36）; in the group A, the treatment combining floatingacupuncture laser with cupping following collateral bloodletting was adopted, and the score of VAS and clinical efficacy before and after treatment in the two groups were compared. Result The differences of VAS scores of the two groups between the time points of after one course of treatment, after the entire treatment, follow up visit three months after the treatment and before treatment were statistically significant （all P〈0.05）. The rate of significant efficiency and total effective rate in the group A were respectively 37.8% and 98.5% （64/65）, and 11.2% and 78.5% （52/65） in the group B. The difference between the two groups was statistically significant after Ridit analysis （P〈0.05）. Conclusion The efficacy of treating PHN by combining floating-acupuncture laser with cupping following collateral bloodletting was significant.
文摘Objective To explore the clinical efficacy of acupuncture combined with vesiculating cupping in treatment of rheumatoid arthritis（RA）. Methods A total of 110 patients with RA were randomly divided into an acupuncture combined with vesiculating cupping group（group A） and an acupuncture combined with non-vesiculating cupping group（group B）. Treatment was conducted once a day in two groups, and ten days were considered as one course of treatment. The total effective rate was observed after treatment for three courses. Results The difference in cured and markable effective rate of group A and group B was obviously significant [81.82%（45/55） vs 18.18%（10/55）, P〈0.01], the difference in total effective rate of group A and group B was significant [96.36%（53/55） vs 69.09%（38/55）, P〈0.05], indicating that the efficacy in group A was significantly superior to that of group B. Conclusion Acupurcture combined with vesiculating cupping therapy achieves more satisfactory efficacy on RA compared with acupuncture combined with nonvesiculating cupping therapy.
文摘Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods Sixty-five patients of neck type of cervical spondylosis were selected and treated with blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point once every two or three days,three times constituted one course and two successive courses were given,then the clinical effect was evaluated.Results The curative rate was 69.2%（45/65）,and the total effective rate was 92.3%（60/65）.Conclusion Blood-letting puncture and cupping at Dong＇s Chōngxiāo（冲霄 Extra） point can be used to treat neck type of cervical spondylosis with simple manipulation and obvious efficacy.
文摘BACKGROUND Wet cupping (WC) is a traditional therapy of skin suction-assisted bloodlettingthat is widely used in modern alternative medicine in Asia and the Middle East.Herein, we report the case of a male who presented with ST-elevation myocardialinfarction (STEMI) and life-threatening anemia and underwent excessive WC.CASE SUMMARY A 55-year-old male presented with chest pain (30 min) and dyspnea (3 wk). Hisinitial electrocardiogram suggested STEMI in the anterior wall. Furthermore, hislaboratory results showed severe anemia with a hemoglobin level of 4.1 g/dL. Ofnote, the patient underwent regular WC therapy for chronic back pain, which hehad recently intensified. His WC practice resulted in life-threatening anemia andeventually STEMI. Percutaneous coronary intervention in the left anteriordescending artery was performed to treat the STEMI. His dyspnea dramaticallyimproved after the transfusion, and his hemoglobin level returned to 14.8 g/dLwithin 2 mo after discharge. He has been uneventful for the last seven years offollow-up.CONCLUSION The current case demonstrates that excessive WC without adequate medicalmonitoring can result in severe anemia, which can further develop into STEMI.
文摘Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy.
文摘Blistering cupping therapy, as a new type of cupping therapy, has attracted more and more attention of clinical doctor and scholars in home and abroad. Blistering cupping therapy achieves better effects through the formation of blistering fluid after suction. However, it is still controversial whether cupping induced blisters are beneficial to recovery of diseases, and the mechanism is still not completely clear. Here on the basis of the traditional cupping method, we aimed to identify the mechanism of blistering cupping from the levels of biomechanics and molecular biology. The negative pressure attraction induced by cupping suck should be of value in increasing pain threshold and relieving pain as well as improving the blood circulation and metabolism. Furthermore, the blistering fluid induced by cupping was the inflammatory substance actually that discharged through the superficial lymphatic vessels, including immunoglobulin, lysozyme, erythrocytes, etc. which could cause the autogenetic inflammatory reaction of selected cupping area, and further activated certain immune pathways including anti-oxidation, anti-apoptosis, tissue repairing and metabolic regulation. Besides, the formation of scar induced by blistering cupping was not only the result of excessive inflammatory response, but also involved in mobilizing the immune response.
