了解多系统萎缩(multiple system atrophy,MSA)80例患者的临床基本特征及CT和MRI的特点。方法:1994年1月~2010年4月收治MSA患者80例,回顾性分析临床资料、CT和MRI资料和随访结果。结果:MSA平均发病年龄54.2±6.8岁,男71%,女29%;患...了解多系统萎缩(multiple system atrophy,MSA)80例患者的临床基本特征及CT和MRI的特点。方法:1994年1月~2010年4月收治MSA患者80例,回顾性分析临床资料、CT和MRI资料和随访结果。结果:MSA平均发病年龄54.2±6.8岁,男71%,女29%;患者多为慢性发病,进行性加重,对美多巴治疗无明显效果。神经系统症状复杂,头颅CT和MRI可见脑干、小脑萎缩,环池及四脑室扩大。结论:MSA临床以自主神经症状、锥体外系、小脑性共济失调为主,CT和MRI主要表现脑干、小脑萎缩,环池及四脑室扩大,但MRI较CT敏感度更高。展开更多
Objective:To analyze the clinical,and imaging features of tuberculosis meningitis(TBM)and to improve its diagnostic accuracy.Method:The clinical data,image features and clinical outcomes of 180 TBM patients from 2011 ...Objective:To analyze the clinical,and imaging features of tuberculosis meningitis(TBM)and to improve its diagnostic accuracy.Method:The clinical data,image features and clinical outcomes of 180 TBM patients from 2011 to 2013 of Shandong Provincial Chest Hospital were analyzed retrospectively.Results:The majority of 180 TBM patients were chronic or subacute onset.Extracranial manifestations of TB accounted for 76.7%(138/180)of the cases.Abnormal brain MRI findings were found in 152 TBM patients(152/180,84.4%),including meningeal thickening and enhancement,tuberculomas,hydrocephalus,and multi-compartment involvement lesions.Three patients died of hydrocephalus.Conclusions:The presence of extracranial tuberculosis and typical brain MRI findings are important contributing factors in order to make an early diagnosis of TBM.Imaging examination is of great importance for the prognosis of tuberculous meningitis.展开更多
文摘了解多系统萎缩(multiple system atrophy,MSA)80例患者的临床基本特征及CT和MRI的特点。方法:1994年1月~2010年4月收治MSA患者80例,回顾性分析临床资料、CT和MRI资料和随访结果。结果:MSA平均发病年龄54.2±6.8岁,男71%,女29%;患者多为慢性发病,进行性加重,对美多巴治疗无明显效果。神经系统症状复杂,头颅CT和MRI可见脑干、小脑萎缩,环池及四脑室扩大。结论:MSA临床以自主神经症状、锥体外系、小脑性共济失调为主,CT和MRI主要表现脑干、小脑萎缩,环池及四脑室扩大,但MRI较CT敏感度更高。
文摘Objective:To analyze the clinical,and imaging features of tuberculosis meningitis(TBM)and to improve its diagnostic accuracy.Method:The clinical data,image features and clinical outcomes of 180 TBM patients from 2011 to 2013 of Shandong Provincial Chest Hospital were analyzed retrospectively.Results:The majority of 180 TBM patients were chronic or subacute onset.Extracranial manifestations of TB accounted for 76.7%(138/180)of the cases.Abnormal brain MRI findings were found in 152 TBM patients(152/180,84.4%),including meningeal thickening and enhancement,tuberculomas,hydrocephalus,and multi-compartment involvement lesions.Three patients died of hydrocephalus.Conclusions:The presence of extracranial tuberculosis and typical brain MRI findings are important contributing factors in order to make an early diagnosis of TBM.Imaging examination is of great importance for the prognosis of tuberculous meningitis.