Background The prognosis of elderly patients with ST-segment elevation myocardial infarction(STEMI)is poor,and information on specific risk factors remains scarce.We aimed to investigate the prevalence and the prognos...Background The prognosis of elderly patients with ST-segment elevation myocardial infarction(STEMI)is poor,and information on specific risk factors remains scarce.We aimed to investigate the prevalence and the prognostic impact of postoperative carbon dioxide combining power(CO_(2)CP)in elderly STEMI patients receiving PCI.Methods Patients≥65 years old with the diagnosis of STEMI who had received PCI was retrospectively enrolled between January 2010 and April 2016 in the Guangdong Provincial People's Hospital.The association between postoperative CO_(2)CP and in-hospital and 1-year mortality was evaluated.Results A total of 775 elderly patients with STEMI were included and divided into two groups according to the lower normal limits of CO_(2)CP:<22 mmol/L(n=180),and≥22 mmol/L(n=595).The incidence of in-hospital death(12.2%vs.4.2%,P<0.001),acute kidney injury(25.0%vs.13.3%,P<0.001)and major adverse clinical events(30.0%vs.8.7%,P<0.001)were significantly higher in patients with a low CO_(2)CP.Multivariate logistic regression analysis showed an independent relationship between CO_(2)CP and in-hospital death[odd ratio(OR):0.88,95%confidential interval(CI):0.80-0.97,P=0.010].This relationship disappeared in one-year mortality[hazard ratio(HR):0.95,95%CI:0.89-1.01,P=0.116].Conclusions Postoperative CO_(2)CP is a feasible predictor during hospitalization for elderly patients with STEMI receiving PCI.展开更多
文摘Background The prognosis of elderly patients with ST-segment elevation myocardial infarction(STEMI)is poor,and information on specific risk factors remains scarce.We aimed to investigate the prevalence and the prognostic impact of postoperative carbon dioxide combining power(CO_(2)CP)in elderly STEMI patients receiving PCI.Methods Patients≥65 years old with the diagnosis of STEMI who had received PCI was retrospectively enrolled between January 2010 and April 2016 in the Guangdong Provincial People's Hospital.The association between postoperative CO_(2)CP and in-hospital and 1-year mortality was evaluated.Results A total of 775 elderly patients with STEMI were included and divided into two groups according to the lower normal limits of CO_(2)CP:<22 mmol/L(n=180),and≥22 mmol/L(n=595).The incidence of in-hospital death(12.2%vs.4.2%,P<0.001),acute kidney injury(25.0%vs.13.3%,P<0.001)and major adverse clinical events(30.0%vs.8.7%,P<0.001)were significantly higher in patients with a low CO_(2)CP.Multivariate logistic regression analysis showed an independent relationship between CO_(2)CP and in-hospital death[odd ratio(OR):0.88,95%confidential interval(CI):0.80-0.97,P=0.010].This relationship disappeared in one-year mortality[hazard ratio(HR):0.95,95%CI:0.89-1.01,P=0.116].Conclusions Postoperative CO_(2)CP is a feasible predictor during hospitalization for elderly patients with STEMI receiving PCI.
