The cosmetic sector is a multibillion-dollar industry that requires constant attention being paid to innovative product development and engagement.Notably,its market value is projected to exceed 750 billion U.S.dollar...The cosmetic sector is a multibillion-dollar industry that requires constant attention being paid to innovative product development and engagement.Notably,its market value is projected to exceed 750 billion U.S.dollars by 2025,and it is expanding as novel,climate-friendly,green,and sustainable components from natural sources are incorporated.This review is written based on the numerous reports on the potential applications of food-derived peptides while focusing on their possible uses in the formulation of cosmeceutical and skincare products.First,the production methods of bioactive peptides linked to cosmeceutical uses are described.Then,we discuss the obtainment and characterization of different anti-inflammatory,antimicrobial,antioxidant,anti-aging,and other pleiotropic peptides with their specific mechanisms,from various food sources.The review concludes with salient considerations of the cost of production and pilot scale operation,stability,compatibility,user safety,site-specificity,and delivery methods,when designing or developing biopeptide-based cosmeceutical products.展开更多
Cosmeceuticals are cosmetic products claimed to have medicinal or drug-like benefits.The term was created in 1990s from cosme(tics)and(pharma)ceuticals.These products are marketed as cosmetics but formulated with biol...Cosmeceuticals are cosmetic products claimed to have medicinal or drug-like benefits.The term was created in 1990s from cosme(tics)and(pharma)ceuticals.These products are marketed as cosmetics but formulated with biologically active ingredients to promote them to have the benefits beyond the traditional moisturizer.Cosmeceuticals,however,are not recognized under any categories of the Food,Drug,and Cosmetic Act.In consideration on rice,it is the most widely consumed staple food for large parts of the world’s human population,especially in Asia,as the source of nutrition and caloric intake.展开更多
Cosmeceuticals are the fastest growing products in the cosmetics field and represent a hybrid between cosmetics and drugs. The main benefits reported for cosmeceutical herbal extracts, used in skin care, include antio...Cosmeceuticals are the fastest growing products in the cosmetics field and represent a hybrid between cosmetics and drugs. The main benefits reported for cosmeceutical herbal extracts, used in skin care, include antioxidant and antimicrobial activities and the tyrosinase inhibiting effect. The aim of this study was to evaluate the antioxidant and antibacterial activities of extracts from <em>Chromolaena odorata, Mitracarpus villosus, Senna alata, Tetradenia riparia, Cannabis sativa</em> and <em>Pterocarpus soyauxii</em> used traditionally in the management of skin and skin annexes pathologies;additionally to determine their microscopical characteristics and their chromatographic fingerprints. Microscopic analyses showed the specific botanical microscopic characters for each plant that constitute the database useful for the identification and authentication of these botanicals. To the best of our knowledge, our work is the first to describe the microscopic histological characters of studied plants except for <em>Cannabis sativa</em>. The results of the TLC chromatographic analysis revealed the richness in phenolic compounds, terpenes in all extracts and <em>Pterocarpus soyauxii </em>contained coumarins. All extracts displayed high ABTS and DPPH radical-scavenging activities connected with their IC<sub>50</sub> values at the concentration range of 1 - 125 μg/mL with<em> Cannabis sativa</em> and <em>Pterocarpus soyauxii </em>as the most active. All plant extracts exhibited antibacterial activity on<em> Escherichia coli</em>, <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> to varying degrees. Cannabis sativa exhibited strong effect on <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. <em>Chromolaena odorata</em> and <em>Tetradenia riparia </em>showed a marked effect on <em>Escherichia coli</em>. Although certain crude extracts from studied botanicals have been shown to be inactive, fractionation studies are needed to determine the active fractions. Obtained biological activities could be related to phytochemicals present in the organic extracts like phenolic compounds and terpenoids. The antioxidant and antibacterial activities of the studied species may have potential therapeutic interest and could justify their use in traditional medicine and local cosmeceutical resources, but further studies are needed, especially <em>in vivo </em>studies, to demonstrate the benefit of these extracts on skin and skin appendages care.展开更多
Amidst the ever-evolving landscape of cosmetics,algae and their derived products have captured substantial worldwide interest,heralding a new era of innovation and sustainability in beauty products.Cosmetic formulatio...Amidst the ever-evolving landscape of cosmetics,algae and their derived products have captured substantial worldwide interest,heralding a new era of innovation and sustainability in beauty products.Cosmetic formulations are witnessing an escalating incorporation of extracts from algal biomass owing to the diverse metabolites making them ideal for studying physiologically active components with unique biochemical properties.The concept of algal biorefinery plays a pivotal role in this context,as it integrates processes to convert algal biomass into a spectrum of valuable products,maximizing resource efficiency and sustainability.Research has proven that the rich and diverse pool of bioactive compounds in algae holds promise for novel nutraceutical,pharmaceutical,and cosmeceutical products.In marine brown algae,compounds like fucoxanthin,polysaccharides,MAAs,and phlorotannins have a variety of functions to combat ultraviolet radiation and protect human skin.Phlorotannins,for instance,contribute to sunscreen and antioxidant properties.The sea environment,teeming with physiologically essential substances,provides an array of cosmeceutical ingredients.Algae also house nutraceutical compounds like polyphenols,carotenoids,fucoidan,alginate,peptides,terpenoids,and polyunsaturated fatty acids,engaging in various biological activities.Algal compounds are emerging as viable alternatives,showcasing beneficial effects even with prolonged use and diverse algae species find widespread application in addressing skin disorders,serving as moisturizers,texture enhancers,sunscreens,and anti-wrinkling agents.This review delves into the bioactive components sourced from algae,especially seaweed and diatoms,unveiling their potential in anti-aging,photo-protection,and skin whitening.The discourse encompasses current applications,challenges,and prospects,highlighting the role of algal biorefinery in providing a sustainable and innovative future for skincare solutions.展开更多
Objective:To investigate the antioxidant and anti-melanogenesis activities of an ultrasonic extract of red sea cucumber,Stichopus japonicus,collected from Jeju Island.Methods:Antioxidant activity experiments were asse...Objective:To investigate the antioxidant and anti-melanogenesis activities of an ultrasonic extract of red sea cucumber,Stichopus japonicus,collected from Jeju Island.Methods:Antioxidant activity experiments were assessed by an electron spin resonance system and a cellular model of immortalized human keratinocytes(HaCaT)to determine its radical scavenging activity and protective effects against 2,2’-azobis(2-amidinopropane)dihydrochloride(AAPH)-induced oxidative stress.Antimelanogenic activity of the ultrasonic extract of red sea cucumber was also examined using the melanoma cell model B16F10 and mushroom tyrosinase.Following the induction byα-melanocytestimulating hormone,the effects of the ultrasonic extract of red sea cucumber on intracellular tyrosinase activity,melanin content and the melanogenic protein expression of microphthalmia-associated transcription factor,tyrosinase,and tyrosinase-related proteins(TRP-1,and TRP-2)were examined.Results:The ultrasonic extract of red sea cucumber significantly scavenged 2,2-diphenyl-1-picrylhydrazyl and alkyl radicals[IC50:(0.924±0.035)and(0.327±0.006)mg/mL,respectively],as well as showed a protective effect against oxidative stress and attenuated generation of intracellular reactive oxygen species on AAPHinduced HaCaT cells,with no cytotoxicity(12.5-400μg/mL).The ultrasonic extract of red sea cucumber also exhibited a tyrosinase inhibitory effect[IC50:(2.750±0.006)mg/mL].Onα-melanocytestimulating hormone-stimulated B16F10 melanoma cells,the ultrasonic extract of red sea cucumber(25-200μg/mL)significantly inhibited not only melanin synthesis and tyrosinase activity,but also protein expressions of microphthalmia-associated transcriptional factor,tyrosinase,TRP-1,and TRP-2.Conclusions:The ultrasonic extract of red sea cucumber shows antioxidant and anti-melanogenic potential and may be a natural candidate for anti-aging as well as a whitening agent in the cosmeceuticals industry.展开更多
A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium（IV） ions by iodide i...A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium（IV） ions by iodide ion was on-line extracted using a polypropylene HFM （hollow fiber membrane） liquid extraction technique. The HFM extraction unit was constructed and used to support an organic solvent （hexane） and separate between the organic phase and aqueous phase. The resulting purple extract was carried to a fiber optic spectrophotometric detector for the measurement at 521 nm. Parameters which affected the extraction efficiency, sensitivity and sample throughput such as iodide （selenium molar ratio, extraction time and washing time between the cycles） were investigated and optimized. A linear dynamic range of 80-373 mg.Lt selenium solution was obtained with an extraction time of 60 sec. The total analysis time including washing was about 180 sec which provided a sample throughput of approximately 20 samples＇hr1 and excluded the sample pre-treatment. The recoveries for the determination of selenium in the forms of selenium dioxide and selenium sulfide were in the range of 103%-104% with 1%-3% RSD （relative standard deviation）. The relative errors of this method which was applied for determination of selenium sulfide levels in an anti-dandruff shampoo and a cosmeceutical bead sample were both less than 2.5%.展开更多
One and the same active ingredient can be used in different pharmaceutical applications to treat and cure diseases.Furthermore,the active ingredient can be used also in cosmetic formulations to care or aid the healing...One and the same active ingredient can be used in different pharmaceutical applications to treat and cure diseases.Furthermore,the active ingredient can be used also in cosmetic formulations to care or aid the healing process.When applied topically via creams or lotions,they are referred as cosmeceuticals.In general,one aims to improve the bioavailability through tailored formulations and careful selection of components.An example is the use of latanoprost in ophthalmology for lowering the intraocular pressure in glaucoma patients with side effects including stimulated growth of eyelashes.Does this open up the possibility of using latanoprost for the local treatment for hair loss?展开更多
Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active ...Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active components and possess potential benefits in skincare products.Methods:Hence,the present study was done to characterize the bioactive constituents of green seaweed Chaetomorpha aerea by using the gas chromatography coupled with high-resolution mass spectrometry technique in ethanolic and methanolic extracts for presenting its cosmetic potential.Results:In analysis,a total of twenty-one different components were found in both the extracts.Their cosmetic potentials have been studied based on previous research studies.In addition,we characterized 9-octadecenoic acid[Z]-,phenylmethyl ester which belongs to benzyloxycarbonyls class.This compound exhibits promising applications in the cosmeceutical sector.This compound has a target peak percentage area(16.64%)with a retention time(39.1 min)in methanolic extract.Conclusion:The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.展开更多
Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products bas...Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products based on consumer self-assessment and to identify those driving factors that influence women’s purchase of these products and to have an insight into their perception and knowledge about these products. Methods: A prospective study was conducted about the use of antiaging cosmetics, consumer satisfaction, skin concerns related with age, importance of younger looking skin and socioeconomic status. Results and Discussion: It was observed in the study that such products do work to improve skin conditions but the claim that wrinkles could be cured completely could not be determined. Participant reported discrepancies between ideal and real effect of antiaging cosmetics. Even if such cosmetic products are expensive people like to spend on these to fulfill the human dream of looking younger.展开更多
Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and interv...Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and intervention pathways,which make it possible to develop effective skin regeneration and repair ingredients.With the rapid development of computational biology,bioinformatics as well as artificial intelligence(A.I.),the development of new ingredients for regenerative medicine has been greatly accelerated,and the success rate has been improved.Some application cases have appeared in topical skin regeneration and repair scenarios.This review will briefly introduce the application of bioactive peptides in skin repair and anti-aging as emerging ingredients in cosmeceutics and emphasize how A.I.based computational biology technology may accelerate the development of innovative peptide molecules and ultimately translate them into potential skin regenerative and anti-aging scenarios.Typically,two research routines have been summarized and current limitations as well as directions were discussed for border applications in future research.展开更多
The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been t...The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been tested over the last decade on over 200,000 people of various ages and ethnicities in different geographic locations around the world. In this study, data were collected from 52,862 patients to compare skin type prevalence between those who presented to doctor’s offices and those who took the quiz without supervision online. The most common skin types varied only slightly between patients that took the quiz online and those that completed the questionnaire in their doctor’s office. This indicates that the prevalence of skin types seen in the doctor’s office is similar to that in the general population and that supervision is not necessary to get an accurate result on the BSTI. [iii] In addition, comparison of data gathered in China, Korea, and the US did not show a significant difference in skin type prevalence between Asian and Caucasian skin types. [iv] This study demonstrates that the English version of the BSTI is valid for English speaking patients online, and in doctors’ offices in the US, China and Korea.展开更多
Background:Fucoxanthin,a carotenoid derived from brown seaweeds,has gained attention as a promising ingredient in skincare due to its antioxidant,anti-inflammatory,anti-aging,and photoprotective properties.Objective:T...Background:Fucoxanthin,a carotenoid derived from brown seaweeds,has gained attention as a promising ingredient in skincare due to its antioxidant,anti-inflammatory,anti-aging,and photoprotective properties.Objective:This review aims to provide a comprehensive analysis of the cosmeceutical potential of fucoxanthin,summarizing findings from in vitro and in vivo studies,as well as clinical trials.Methods:A systematic review(2000–2023)using PubMed,Scopus,Web of Science,and Google Scholar identified studies on fucoxanthin's anti-aging and skin-related properties.Following a three-phase screening process(titles,abstracts,and full-text evaluation),14 relevant studies were selected—9 in vitro and 5 in vivo/clinical—exploring fucoxanthin's effects in cosmetics and skincare.Key outcomes,including effects on oxidative stress,collagen synthesis,melanin production,and skin health,were analyzed.Results:The results from nine in vitro studies showed that fucoxanthin effectively reduces oxidative stress,enhances procollagen synthesis,inhibits matrix metalloproteinases,and suppresses melanin synthesis in various skin cell lines,indicating its potential in preventing skin aging,reducing pigmentation,and improving skin structure and elasticity.In vivo studies,including experiments on ultraviolet B(UVB)-irradiated guinea pigs and hairless mice,demonstrated that fucoxanthin could protect against ultraviolet(UV)-induced skin damage,prevent wrinkle formation,and reduce inflammation.Furthermore,a clinical study involving Korean women confirmed significant improvements in skin moisture,elasticity,and reduction of wrinkles after eight weeks of applying a fucoxanthin-based cream.This review underscores the increasing evidence of fucoxanthin's efficacy in the skin and highlights its cosmetic potential as a main ingredient of innovative,natural,and sustainable cosmeceutical formulations targeting the skin's overall health and preventing aging.Conclusions:Fucoxanthin demonstrates considerable potential as a natural and sustainable component in cosmeceutical formulations for skin beauty and anti-aging.Stability issues,together with bioavailability problems and sourcing,remain an ongoing obstacle to further development.Further research on clinical trials alongside new formulation strategies will help address restrictions that block fucoxanthin from successful cosmetics applications.展开更多
文摘The cosmetic sector is a multibillion-dollar industry that requires constant attention being paid to innovative product development and engagement.Notably,its market value is projected to exceed 750 billion U.S.dollars by 2025,and it is expanding as novel,climate-friendly,green,and sustainable components from natural sources are incorporated.This review is written based on the numerous reports on the potential applications of food-derived peptides while focusing on their possible uses in the formulation of cosmeceutical and skincare products.First,the production methods of bioactive peptides linked to cosmeceutical uses are described.Then,we discuss the obtainment and characterization of different anti-inflammatory,antimicrobial,antioxidant,anti-aging,and other pleiotropic peptides with their specific mechanisms,from various food sources.The review concludes with salient considerations of the cost of production and pilot scale operation,stability,compatibility,user safety,site-specificity,and delivery methods,when designing or developing biopeptide-based cosmeceutical products.
文摘Cosmeceuticals are cosmetic products claimed to have medicinal or drug-like benefits.The term was created in 1990s from cosme(tics)and(pharma)ceuticals.These products are marketed as cosmetics but formulated with biologically active ingredients to promote them to have the benefits beyond the traditional moisturizer.Cosmeceuticals,however,are not recognized under any categories of the Food,Drug,and Cosmetic Act.In consideration on rice,it is the most widely consumed staple food for large parts of the world’s human population,especially in Asia,as the source of nutrition and caloric intake.
文摘Cosmeceuticals are the fastest growing products in the cosmetics field and represent a hybrid between cosmetics and drugs. The main benefits reported for cosmeceutical herbal extracts, used in skin care, include antioxidant and antimicrobial activities and the tyrosinase inhibiting effect. The aim of this study was to evaluate the antioxidant and antibacterial activities of extracts from <em>Chromolaena odorata, Mitracarpus villosus, Senna alata, Tetradenia riparia, Cannabis sativa</em> and <em>Pterocarpus soyauxii</em> used traditionally in the management of skin and skin annexes pathologies;additionally to determine their microscopical characteristics and their chromatographic fingerprints. Microscopic analyses showed the specific botanical microscopic characters for each plant that constitute the database useful for the identification and authentication of these botanicals. To the best of our knowledge, our work is the first to describe the microscopic histological characters of studied plants except for <em>Cannabis sativa</em>. The results of the TLC chromatographic analysis revealed the richness in phenolic compounds, terpenes in all extracts and <em>Pterocarpus soyauxii </em>contained coumarins. All extracts displayed high ABTS and DPPH radical-scavenging activities connected with their IC<sub>50</sub> values at the concentration range of 1 - 125 μg/mL with<em> Cannabis sativa</em> and <em>Pterocarpus soyauxii </em>as the most active. All plant extracts exhibited antibacterial activity on<em> Escherichia coli</em>, <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> to varying degrees. Cannabis sativa exhibited strong effect on <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. <em>Chromolaena odorata</em> and <em>Tetradenia riparia </em>showed a marked effect on <em>Escherichia coli</em>. Although certain crude extracts from studied botanicals have been shown to be inactive, fractionation studies are needed to determine the active fractions. Obtained biological activities could be related to phytochemicals present in the organic extracts like phenolic compounds and terpenoids. The antioxidant and antibacterial activities of the studied species may have potential therapeutic interest and could justify their use in traditional medicine and local cosmeceutical resources, but further studies are needed, especially <em>in vivo </em>studies, to demonstrate the benefit of these extracts on skin and skin appendages care.
基金Financial support for this study had been provided by the AISTDF Secretariat,Science&Engineering Research Board(SERB),India(Grant No.CRD/2022/000595).
文摘Amidst the ever-evolving landscape of cosmetics,algae and their derived products have captured substantial worldwide interest,heralding a new era of innovation and sustainability in beauty products.Cosmetic formulations are witnessing an escalating incorporation of extracts from algal biomass owing to the diverse metabolites making them ideal for studying physiologically active components with unique biochemical properties.The concept of algal biorefinery plays a pivotal role in this context,as it integrates processes to convert algal biomass into a spectrum of valuable products,maximizing resource efficiency and sustainability.Research has proven that the rich and diverse pool of bioactive compounds in algae holds promise for novel nutraceutical,pharmaceutical,and cosmeceutical products.In marine brown algae,compounds like fucoxanthin,polysaccharides,MAAs,and phlorotannins have a variety of functions to combat ultraviolet radiation and protect human skin.Phlorotannins,for instance,contribute to sunscreen and antioxidant properties.The sea environment,teeming with physiologically essential substances,provides an array of cosmeceutical ingredients.Algae also house nutraceutical compounds like polyphenols,carotenoids,fucoidan,alginate,peptides,terpenoids,and polyunsaturated fatty acids,engaging in various biological activities.Algal compounds are emerging as viable alternatives,showcasing beneficial effects even with prolonged use and diverse algae species find widespread application in addressing skin disorders,serving as moisturizers,texture enhancers,sunscreens,and anti-wrinkling agents.This review delves into the bioactive components sourced from algae,especially seaweed and diatoms,unveiling their potential in anti-aging,photo-protection,and skin whitening.The discourse encompasses current applications,challenges,and prospects,highlighting the role of algal biorefinery in providing a sustainable and innovative future for skincare solutions.
基金supported by a research grant funded by the Korea Institute of Ocean Science and Technology(PE99722)supported by Soonchunhyang University Research Fund.
文摘Objective:To investigate the antioxidant and anti-melanogenesis activities of an ultrasonic extract of red sea cucumber,Stichopus japonicus,collected from Jeju Island.Methods:Antioxidant activity experiments were assessed by an electron spin resonance system and a cellular model of immortalized human keratinocytes(HaCaT)to determine its radical scavenging activity and protective effects against 2,2’-azobis(2-amidinopropane)dihydrochloride(AAPH)-induced oxidative stress.Antimelanogenic activity of the ultrasonic extract of red sea cucumber was also examined using the melanoma cell model B16F10 and mushroom tyrosinase.Following the induction byα-melanocytestimulating hormone,the effects of the ultrasonic extract of red sea cucumber on intracellular tyrosinase activity,melanin content and the melanogenic protein expression of microphthalmia-associated transcription factor,tyrosinase,and tyrosinase-related proteins(TRP-1,and TRP-2)were examined.Results:The ultrasonic extract of red sea cucumber significantly scavenged 2,2-diphenyl-1-picrylhydrazyl and alkyl radicals[IC50:(0.924±0.035)and(0.327±0.006)mg/mL,respectively],as well as showed a protective effect against oxidative stress and attenuated generation of intracellular reactive oxygen species on AAPHinduced HaCaT cells,with no cytotoxicity(12.5-400μg/mL).The ultrasonic extract of red sea cucumber also exhibited a tyrosinase inhibitory effect[IC50:(2.750±0.006)mg/mL].Onα-melanocytestimulating hormone-stimulated B16F10 melanoma cells,the ultrasonic extract of red sea cucumber(25-200μg/mL)significantly inhibited not only melanin synthesis and tyrosinase activity,but also protein expressions of microphthalmia-associated transcriptional factor,tyrosinase,TRP-1,and TRP-2.Conclusions:The ultrasonic extract of red sea cucumber shows antioxidant and anti-melanogenic potential and may be a natural candidate for anti-aging as well as a whitening agent in the cosmeceuticals industry.
文摘A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium（IV） ions by iodide ion was on-line extracted using a polypropylene HFM （hollow fiber membrane） liquid extraction technique. The HFM extraction unit was constructed and used to support an organic solvent （hexane） and separate between the organic phase and aqueous phase. The resulting purple extract was carried to a fiber optic spectrophotometric detector for the measurement at 521 nm. Parameters which affected the extraction efficiency, sensitivity and sample throughput such as iodide （selenium molar ratio, extraction time and washing time between the cycles） were investigated and optimized. A linear dynamic range of 80-373 mg.Lt selenium solution was obtained with an extraction time of 60 sec. The total analysis time including washing was about 180 sec which provided a sample throughput of approximately 20 samples＇hr1 and excluded the sample pre-treatment. The recoveries for the determination of selenium in the forms of selenium dioxide and selenium sulfide were in the range of 103%-104% with 1%-3% RSD （relative standard deviation）. The relative errors of this method which was applied for determination of selenium sulfide levels in an anti-dandruff shampoo and a cosmeceutical bead sample were both less than 2.5%.
文摘One and the same active ingredient can be used in different pharmaceutical applications to treat and cure diseases.Furthermore,the active ingredient can be used also in cosmetic formulations to care or aid the healing process.When applied topically via creams or lotions,they are referred as cosmeceuticals.In general,one aims to improve the bioavailability through tailored formulations and careful selection of components.An example is the use of latanoprost in ophthalmology for lowering the intraocular pressure in glaucoma patients with side effects including stimulated growth of eyelashes.Does this open up the possibility of using latanoprost for the local treatment for hair loss?
基金financed by national funds through FCT-Foundation for Science and Technology,I.P.,within the scope of the projects UIDB/04292/2020 of MARE-Marine and Environmental Sciences Centre.
文摘Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active components and possess potential benefits in skincare products.Methods:Hence,the present study was done to characterize the bioactive constituents of green seaweed Chaetomorpha aerea by using the gas chromatography coupled with high-resolution mass spectrometry technique in ethanolic and methanolic extracts for presenting its cosmetic potential.Results:In analysis,a total of twenty-one different components were found in both the extracts.Their cosmetic potentials have been studied based on previous research studies.In addition,we characterized 9-octadecenoic acid[Z]-,phenylmethyl ester which belongs to benzyloxycarbonyls class.This compound exhibits promising applications in the cosmeceutical sector.This compound has a target peak percentage area(16.64%)with a retention time(39.1 min)in methanolic extract.Conclusion:The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.
文摘Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products based on consumer self-assessment and to identify those driving factors that influence women’s purchase of these products and to have an insight into their perception and knowledge about these products. Methods: A prospective study was conducted about the use of antiaging cosmetics, consumer satisfaction, skin concerns related with age, importance of younger looking skin and socioeconomic status. Results and Discussion: It was observed in the study that such products do work to improve skin conditions but the claim that wrinkles could be cured completely could not be determined. Participant reported discrepancies between ideal and real effect of antiaging cosmetics. Even if such cosmetic products are expensive people like to spend on these to fulfill the human dream of looking younger.
基金supported by the Guangdong Basic and Applied Basic Research Foundation(No.2023A1515030047)Zhejiang Provincial Department of Agriculture and Rural Affairs(2022SNJF078).
文摘Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and intervention pathways,which make it possible to develop effective skin regeneration and repair ingredients.With the rapid development of computational biology,bioinformatics as well as artificial intelligence(A.I.),the development of new ingredients for regenerative medicine has been greatly accelerated,and the success rate has been improved.Some application cases have appeared in topical skin regeneration and repair scenarios.This review will briefly introduce the application of bioactive peptides in skin repair and anti-aging as emerging ingredients in cosmeceutics and emphasize how A.I.based computational biology technology may accelerate the development of innovative peptide molecules and ultimately translate them into potential skin regenerative and anti-aging scenarios.Typically,two research routines have been summarized and current limitations as well as directions were discussed for border applications in future research.
文摘The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been tested over the last decade on over 200,000 people of various ages and ethnicities in different geographic locations around the world. In this study, data were collected from 52,862 patients to compare skin type prevalence between those who presented to doctor’s offices and those who took the quiz without supervision online. The most common skin types varied only slightly between patients that took the quiz online and those that completed the questionnaire in their doctor’s office. This indicates that the prevalence of skin types seen in the doctor’s office is similar to that in the general population and that supervision is not necessary to get an accurate result on the BSTI. [iii] In addition, comparison of data gathered in China, Korea, and the US did not show a significant difference in skin type prevalence between Asian and Caucasian skin types. [iv] This study demonstrates that the English version of the BSTI is valid for English speaking patients online, and in doctors’ offices in the US, China and Korea.
基金the Ministry of Higher Education of Malaysia(MOHE)and She Empire Sdn Bhd for their financial support under the Industry Matching Programme(IMaP)(Ref:IMaP/1/2024/SKK15/UTHM//1)for the project titled“FusionDerm Validation:Pioneering the Next-Generation Multipurpose Cream with Fucoxanthin for Enhanced Urban Skin Defense and Anti-Pollution Efficacy.”。
文摘Background:Fucoxanthin,a carotenoid derived from brown seaweeds,has gained attention as a promising ingredient in skincare due to its antioxidant,anti-inflammatory,anti-aging,and photoprotective properties.Objective:This review aims to provide a comprehensive analysis of the cosmeceutical potential of fucoxanthin,summarizing findings from in vitro and in vivo studies,as well as clinical trials.Methods:A systematic review(2000–2023)using PubMed,Scopus,Web of Science,and Google Scholar identified studies on fucoxanthin's anti-aging and skin-related properties.Following a three-phase screening process(titles,abstracts,and full-text evaluation),14 relevant studies were selected—9 in vitro and 5 in vivo/clinical—exploring fucoxanthin's effects in cosmetics and skincare.Key outcomes,including effects on oxidative stress,collagen synthesis,melanin production,and skin health,were analyzed.Results:The results from nine in vitro studies showed that fucoxanthin effectively reduces oxidative stress,enhances procollagen synthesis,inhibits matrix metalloproteinases,and suppresses melanin synthesis in various skin cell lines,indicating its potential in preventing skin aging,reducing pigmentation,and improving skin structure and elasticity.In vivo studies,including experiments on ultraviolet B(UVB)-irradiated guinea pigs and hairless mice,demonstrated that fucoxanthin could protect against ultraviolet(UV)-induced skin damage,prevent wrinkle formation,and reduce inflammation.Furthermore,a clinical study involving Korean women confirmed significant improvements in skin moisture,elasticity,and reduction of wrinkles after eight weeks of applying a fucoxanthin-based cream.This review underscores the increasing evidence of fucoxanthin's efficacy in the skin and highlights its cosmetic potential as a main ingredient of innovative,natural,and sustainable cosmeceutical formulations targeting the skin's overall health and preventing aging.Conclusions:Fucoxanthin demonstrates considerable potential as a natural and sustainable component in cosmeceutical formulations for skin beauty and anti-aging.Stability issues,together with bioavailability problems and sourcing,remain an ongoing obstacle to further development.Further research on clinical trials alongside new formulation strategies will help address restrictions that block fucoxanthin from successful cosmetics applications.
