The absolute vacuum is the Mocombeian ontological name for the fifth dimensional probability wavefunction(the world of noumena,i.e.,the in-itself)that gives rise to the material worlds,their facts,relations of ideas,a...The absolute vacuum is the Mocombeian ontological name for the fifth dimensional probability wavefunction(the world of noumena,i.e.,the in-itself)that gives rise to the material worlds,their facts,relations of ideas,and mathematical principles,we as a species experience.In this article,I utilize Mocombe’s phenomenological structural epistemology emanating out of the aforementioned ontology of the absolute vacuum to refute Kant’s epistemological unknowability of the noumenal world,i.e.,the absolute vacuum in Mocombeian epistemology.展开更多
The idea to replicate in a machine human consciousness,understood as an immediate first-person subjective experience,becomes one of the greatest challenges of our time.Scientific understanding of the nature of phenome...The idea to replicate in a machine human consciousness,understood as an immediate first-person subjective experience,becomes one of the greatest challenges of our time.Scientific understanding of the nature of phenomenal consciousness may require an expansion of the scientific method itself.While this resolution is postponed,the task of reproducing the consciousness phenomenon in a computer should be approached within the framework of functionalism.Proposed so far theories of this sort appear problematic.An approach to implementing humanlike consciousness is proposed here based on BICA(biologically inspired cognitive architectures)combined with LLM(large language models).The concept is illustrated by example of a virtual tutor.It is argued that final solutions can be obtained in a purely neuromorphic form,which will enable their further adaptation,growth,and evolution.We start from discussion of the ontological problem of consciousness and its temporary nonreductive solution,which makes a scientific study possible.The main hypothesis for the proposed study is formulated based on the BICA Challenge in terms of the eBICA cognitive architecture.Only the limited case of socially emotional consciousness is analyzed as example.It is explained how LLM,being not conscious on their own,accessible via ChatGPT,can be connected to eBICA,used to build a conscious prototype and validate its claimed property.Selected example of a virtual tutor further illustrates how this technology will allow the tutor to develop human-level teacher-student relationships that will increase the efficiency of tutoring.Future prospects for the proposed direction of research include a variety of sentient agents to be created for the many practical human needs with the possibility of their further autonomous evolution.展开更多
Purpose:This study aims to foster a dialog between the experiences and identities of Nigerian female breast cancer survivors and Margaret Newman’s theory of health as expanding consciousness.The theory was employed t...Purpose:This study aims to foster a dialog between the experiences and identities of Nigerian female breast cancer survivors and Margaret Newman’s theory of health as expanding consciousness.The theory was employed to explore and describe the structure and meaning of these survivors’experiences and identities.Methods:Twenty-two participants were interviewed using a qualitative approach.The interviews were digitally recorded and transcribed verbatim.Data analysis was conducted using NVivo 14 software to identify recurring patterns within the data.Results:Three core themes emerged:(1)Encountering Selfhood-Otherhood in the survivorship journey,(2)navigating the rhythms of change,and(3)living the paradox of order and disorder.These themes reflect the unique and paradoxical rhythm of life as a breast cancer survivor,integrating these experiences conceptually.Conclusions:This study illuminates how Nigerian breast cancer survivors construct the patterns of meaning of their experiences by shifting the focus from solely evidence-based interventions to a deeper exploration of lived experience,cultural narratives,and expanding consciousness.Through compassionate and insightful nursing interactions,women can explore their evolving identities,foster resilience,and redefine their lives in meaningful and fulfilling ways within their unique contexts.Implications for Cancer Survivors:Greater attention is required to address the emotional,temporal,and economic dimensions of breast cancer survivorship in Nigeria.Nurses play a crucial role in helping survivors find meaning in their experiences,recognizing that order and disorder in life are integral to expanding consciousness.Survivors should be empowered to identify their patterns of living and leverage their strengths in navigating the survivorship journey and finding meaning in their lives.展开更多
Objective:The objective of this study was to compare the effect of nurse and beloved family member’s recording voice on consciousness and physical parameters in patients with coma state.Materials and Methods:A random...Objective:The objective of this study was to compare the effect of nurse and beloved family member’s recording voice on consciousness and physical parameters in patients with coma state.Materials and Methods:A randomized control trial parallel group design was conducted among 45 comatose patients divided into two intervention groups,i.e.nurse voice stimulus group,receiving nurses voice with standard care,family members voice stimulus group receiving their beloved family member voice with standard care and one control group receiving only standard care in medicine intensive care unit.The intervention was provided three times a day,each lasting 5 min for 7 days in addition to standard care.Repeated measure analysis of variance and independent t-test were used to compare within and between groups,respectively.Results:The study found significant differences in Glasgow coma scale(GCS)scores within both the nurse(F=2.78,P=0.042)and family member(F=10.27,P=0.0001)voice stimulus groups over 7 days.Comparing GCS scores between intervention groups showed significant variations before(P=0.028),during(P=0.047),and after(P=0.036)the intervention on day 7.Comparing GCS scores between the family members’voice stimulus group and the control group,significant changes were observed on days 5 and 7(P=0.043,0.030,0.030,and 0.014,0.012,0.012)before,during,and after the intervention.Conclusions:The use of beloved family members’voices proved more effective in elevating the patients’level of consciousness compared to both the nurse voice stimulus group and the control group.展开更多
Against the strategic backdrop of forging and strengthening the consciousness of the Chinese national community in the new era,universities in border areas,as crucial platforms for the integration of multi-ethnic cult...Against the strategic backdrop of forging and strengthening the consciousness of the Chinese national community in the new era,universities in border areas,as crucial platforms for the integration of multi-ethnic cultures,shoulder the significant mission of enhancing ethnic unity and promoting outstanding traditional Chinese culture.As an important carrier of Chinese culture,ethnic music not only contains profound historical memories and emotional identities but also demonstrates a powerful cultural and educational function in the teaching of border universities.Based on the actual situation of universities in border areas,this paper analyzes the unique value of ethnic music in cultivating students’national identity,cultural identity,and emotional identity,and explores effective paths for it to empower the forging and strengthening of the consciousness of the Chinese national community in teaching practice.By combining policy orientations and teaching status quo,the paper points out the main dilemmas such as single curriculum content,insufficient integration of ideological and political education,and a lack of practical resources,and proposes countermeasures such as strengthening the integration of ideological and political education,optimizing the curriculum structure,and expanding practical platforms.Through the deepening and innovation of ethnic music education,border universities can effectively enhance students’cultural consciousness and cultural confidence,providing solid educational support for forging and strengthening the consciousness of the Chinese national community.This paper has positive significance for promoting the high-quality development of education in border universities and constructing a new-era ethnic unity and progress education system.展开更多
Among the existing research on the treatment of disorders of consciousness(DOC),deep brain stimulation(DBS)offers a highly promising therapeutic approach.This comprehensive review documents the historical development ...Among the existing research on the treatment of disorders of consciousness(DOC),deep brain stimulation(DBS)offers a highly promising therapeutic approach.This comprehensive review documents the historical development of DBS and its role in the treatment of DOC,tracing its progression from an experimental therapy to a detailed modulation approach based on the mesocircuit model hypothesis.The mesocircuit model hypothesis suggests that DOC arises from disruptions in a critical network of brain regions,providing a framework for refining DBS targets.We also discuss the multimodal approaches for assessing patients with DOC,encompassing clinical behavioral scales,electrophysiological assessment,and neuroimaging techniques methods.During the evolution of DOC therapy,the segmentation of central nuclei,the recording of single-neurons,and the analysis of local field potentials have emerged as favorable technical factors that enhance the efficacy of DBS treatment.Advances in computational models have also facilitated a deeper exploration of the neural dynamics associated with DOC,linking neuron-level dynamics with macroscopic behavioral changes.Despite showing promising outcomes,challenges remain in patient selection,precise target localization,and the determination of optimal stimulation parameters.Future research should focus on conducting large-scale controlled studies to delve into the pathophysiological mechanisms of DOC.It is imperative to further elucidate the precise modulatory effects of DBS on thalamo-cortical and cortico-cortical functional connectivity networks.Ultimately,by optimizing neuromodulation strategies,we aim to substantially enhance therapeutic outcomes and greatly expedite the process of consciousness recovery in patients.展开更多
This paper explores pathways for integrating the Chinese national community consciousness into ideological and political education in college English courses.Through an in-depth analysis of current teaching practices,...This paper explores pathways for integrating the Chinese national community consciousness into ideological and political education in college English courses.Through an in-depth analysis of current teaching practices,it highlights the critical significance and urgent need for embedding this consciousness.The study proposes practical implementation strategies encompassing scientific curriculum design,in-depth content exploration,and innovative teaching methodologies.These approaches collectively facilitate the harmonious integration of knowledge transmission,skill development,and value guidance in English education.They strengthen students’identity with the Chinese national community and emotional attachment to it,while enhancing their ability to disseminate China’s cultural heritage through English communication.This framework supports the cultivation of new-era talents with both patriotic dedication and global vision.展开更多
The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. Howe...The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. However, the results were not satisfactory. In this study, we changed the constituent order of subjects＇ two-character names to create derived names. The subject＇s derived names, together with tones and their own names, were used as auditory stimuli in event-related potential experiments. Healthy controls and unconscious patients were included in this study and made to listen to these auditory stimuli. In the two paradigms, a sine tone followed by the subject＇s own name and the subject＇s derived name followed by the subject＇s own name were used as standard and deviant stimuli, respectively. The results showed that all healthy controls had the P300 using both paradigms, and that the P300 in the second paradigm had a longer latency and two peaks. All minimally conscious state patients had the P300 in the first paradigm and the majority of them had the P300 in the second paradigm. Most vegetative state patients had no P300. Patients who showed the P300 in the two paradigms had more residual consciousness, and patients with the two-peak P300 had a higher probability of awakening within a short time. Our experimental findings suggest that the P300 event-related potential could reflect the conscious state of unconscious patients.展开更多
When presented with visual stimuli of face images,the ventral stream visual cortex of the human brain exhibits face-specific activity that is modulated by the physical properties of the input images.However,it is stil...When presented with visual stimuli of face images,the ventral stream visual cortex of the human brain exhibits face-specific activity that is modulated by the physical properties of the input images.However,it is still unclear whether this activity relates to conscious face perception.We explored this issue by using the human intracranial electroencephalography technique.Our results showed that face-specific activity in the ventral stream visual cortex was significantly higher when the subjects subjectively saw faces than when they did not,even when face stimuli were presented in both conditions.In addition,the face-specific neural activity exhibited a more reliable neural response and increased posterior-anterior direction information transfer in the“seen”condition than the“unseen”condition.Furthermore,the face-specific neural activity was significantly correlated with performance.These findings support the view that face-specific activity in the ventral stream visual cortex is linked to conscious face perception.展开更多
Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields t...Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CSB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining SST and CSB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of SST and CSB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed SST with nonconscious natural breathing for 20 min. The same participants performed SST in combination with CSB (2 s inspiratory and 4 s expiratory) for 20 min on another day. Salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: SST decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of SST and CSB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of SST and CSB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.展开更多
The purpose of this study is to offer a better comprehension of what happens in organizations when enhancing organizational culture through consciousness by linking the market-oriented ecosystem variables and analyzin...The purpose of this study is to offer a better comprehension of what happens in organizations when enhancing organizational culture through consciousness by linking the market-oriented ecosystem variables and analyzing their relationship with a conscious organization.Design and methodology:Two questionnaires were used to test the hypotheses,the market-oriented ecosystem 38-item(Yeung&Ulrich,2019),and the conscious organization model 7-item adaptation(Sisoda,2018).Pearson correlations were calculated to measure the strength of the linear relationship among the variables involved in each one of the hypotheses,and coefficient alpha(coefficient𝛼)was used to analyze the reliability,to measure the internal consistency of the scales.Relevant findings:Context,ecosystem organizational structure,governance,and people ecosystem were positively correlated to a conscious organization.The originality of this study is based on use of the interaction among the variables of the market-oriented ecosystem model(continuous changing context,ecosystem organizational structure,governance,and people ecosystem)and a conscious organizational culture.Finally,the practical implications of having high levels of the market-oriented ecosystem variables predict high level of consciousness in organizations.These variables require careful consideration,a proactive planning process to enhance organizational culture through consciousness.展开更多
This article explores the intersection of the Eight-Circuit Model of Consciousness (ECM), initially conceptualized by Timothy Leary and expanded by Robert Anton Wilson, and its implications for mind-body health. By an...This article explores the intersection of the Eight-Circuit Model of Consciousness (ECM), initially conceptualized by Timothy Leary and expanded by Robert Anton Wilson, and its implications for mind-body health. By analyzing each circuit’s role in human consciousness, we discuss how activating and balancing these circuits can lead to enhanced psychological well-being, stress reduction, and overall physical health. Recent research is integrated to provide a contemporary understanding of how the ECM can be applied to modern mind-body therapies, with a focus on both theoretical implications and practical applications.展开更多
A prestigious conference claimed recently a revolution in neuroscience to understand consciousness.In this paper it is shown that this revolution already came,revealing the determinant role of information for human an...A prestigious conference claimed recently a revolution in neuroscience to understand consciousness.In this paper it is shown that this revolution already came,revealing the determinant role of information for human and living structures,both for their structuration and behavior,explaining consciousness at human as the result of the activity of the Informational System of Human and Living Structures.For this,it is emphasized and discussed the informational structure of the eukaryotic cell,the basic/representative composing unit of the multicellular body of human,animals,and plants,showing that the composition and functions of the informational system are basically similar with that of human.To reveal the driving role of informational mechanisms in human and subhuman organisms,it is introduced the concept of matter-related information,showing that information can be hidden/“embodied”or released/“disembodied”in or from the elemental micro/macro components of the body,during the multiple chain/cascade interactions including transduction processes.It is shown that such interactions are initiated from two main categories of informational sources:implicit(genetic)and explicit(external/internal)sources,the first category leading to structuration of the body and the second the reactive behavior.Consciousness in human and subhuman organisms,expressed by two corresponding informational relations,is the result of the release of information by the mind,acting as an informational operator/device,the development degree of mind and consciousness depending on the complexity degree and adaptation.An analogy of this Informational Model of Human and Living Structures(IMHLS)with the ancient model of chakras is highlighted,showing that these models support each other,applied with beneficial effects in Reiki technique and music-based cognitive multi-task therapy for neuro-rehabilitation.展开更多
Purpose:What factors influence conscious consumerism,especially related to race and gender identities?This scholarship explores three white women-led social responsibility organizations’(SROs)aspirations to encourage...Purpose:What factors influence conscious consumerism,especially related to race and gender identities?This scholarship explores three white women-led social responsibility organizations’(SROs)aspirations to encourage conscious consumerism as well as factors that influence conscious consumerism.Design/methodology/approach:Using the Black feminist thought and sustainability development theory,the data were analyzed using a thematic analysis to explore the activation of the white savior industrial complex(WSIC)in SROs.Interviews provided in-depth knowledge of the SRO culture including,but not limited to,insight on social exclusion and partnerships.Findings:Noonday Collection,Sseko Designs,and Trades of Hope,all SROs,aspire to be dedicated to people,planet,and profit and encourage conscious consumerism as a means for their customer base and sales consultants to“do their part”,and yet,an unintended consequence of the SROs’work is social exclusion and white saviorism.Originality:This scholarship investigates what can be done to dismantle the overreliance of conscious consumerism in an effort to finally strip white saviorism,and its role in the white savior industrial complex(WSIC),of its power.展开更多
This work explores the axiology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory(CFT)within the larger body of contemporary o...This work explores the axiology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory(CFT)within the larger body of contemporary ontological debates regarding the nature,origin,and constitution of consciousness in the universe.The work goes on to highlight the manifestation of Mocombe’s consciousness field in the material resource framework that is the earth,and the nature and origins of ethics and values.展开更多
This work explores the epistemology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory within the larger body of contemporary o...This work explores the epistemology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory within the larger body of contemporary ontological debates regarding the nature,origin,and constitution of consciousness in the universe.The work goes on to highlight the manifestation of Mocombe’s consciousness field from the absolute vacuum to and in the material resource framework that is the earth,and how we come to know about and experience both(the absolute vacuum and the material worlds that it creates).展开更多
文摘The absolute vacuum is the Mocombeian ontological name for the fifth dimensional probability wavefunction(the world of noumena,i.e.,the in-itself)that gives rise to the material worlds,their facts,relations of ideas,and mathematical principles,we as a species experience.In this article,I utilize Mocombe’s phenomenological structural epistemology emanating out of the aforementioned ontology of the absolute vacuum to refute Kant’s epistemological unknowability of the noumenal world,i.e.,the absolute vacuum in Mocombeian epistemology.
基金Supported by Russian Science Foundation(22-11-00213).
文摘The idea to replicate in a machine human consciousness,understood as an immediate first-person subjective experience,becomes one of the greatest challenges of our time.Scientific understanding of the nature of phenomenal consciousness may require an expansion of the scientific method itself.While this resolution is postponed,the task of reproducing the consciousness phenomenon in a computer should be approached within the framework of functionalism.Proposed so far theories of this sort appear problematic.An approach to implementing humanlike consciousness is proposed here based on BICA(biologically inspired cognitive architectures)combined with LLM(large language models).The concept is illustrated by example of a virtual tutor.It is argued that final solutions can be obtained in a purely neuromorphic form,which will enable their further adaptation,growth,and evolution.We start from discussion of the ontological problem of consciousness and its temporary nonreductive solution,which makes a scientific study possible.The main hypothesis for the proposed study is formulated based on the BICA Challenge in terms of the eBICA cognitive architecture.Only the limited case of socially emotional consciousness is analyzed as example.It is explained how LLM,being not conscious on their own,accessible via ChatGPT,can be connected to eBICA,used to build a conscious prototype and validate its claimed property.Selected example of a virtual tutor further illustrates how this technology will allow the tutor to develop human-level teacher-student relationships that will increase the efficiency of tutoring.Future prospects for the proposed direction of research include a variety of sentient agents to be created for the many practical human needs with the possibility of their further autonomous evolution.
文摘Purpose:This study aims to foster a dialog between the experiences and identities of Nigerian female breast cancer survivors and Margaret Newman’s theory of health as expanding consciousness.The theory was employed to explore and describe the structure and meaning of these survivors’experiences and identities.Methods:Twenty-two participants were interviewed using a qualitative approach.The interviews were digitally recorded and transcribed verbatim.Data analysis was conducted using NVivo 14 software to identify recurring patterns within the data.Results:Three core themes emerged:(1)Encountering Selfhood-Otherhood in the survivorship journey,(2)navigating the rhythms of change,and(3)living the paradox of order and disorder.These themes reflect the unique and paradoxical rhythm of life as a breast cancer survivor,integrating these experiences conceptually.Conclusions:This study illuminates how Nigerian breast cancer survivors construct the patterns of meaning of their experiences by shifting the focus from solely evidence-based interventions to a deeper exploration of lived experience,cultural narratives,and expanding consciousness.Through compassionate and insightful nursing interactions,women can explore their evolving identities,foster resilience,and redefine their lives in meaningful and fulfilling ways within their unique contexts.Implications for Cancer Survivors:Greater attention is required to address the emotional,temporal,and economic dimensions of breast cancer survivorship in Nigeria.Nurses play a crucial role in helping survivors find meaning in their experiences,recognizing that order and disorder in life are integral to expanding consciousness.Survivors should be empowered to identify their patterns of living and leverage their strengths in navigating the survivorship journey and finding meaning in their lives.
文摘Objective:The objective of this study was to compare the effect of nurse and beloved family member’s recording voice on consciousness and physical parameters in patients with coma state.Materials and Methods:A randomized control trial parallel group design was conducted among 45 comatose patients divided into two intervention groups,i.e.nurse voice stimulus group,receiving nurses voice with standard care,family members voice stimulus group receiving their beloved family member voice with standard care and one control group receiving only standard care in medicine intensive care unit.The intervention was provided three times a day,each lasting 5 min for 7 days in addition to standard care.Repeated measure analysis of variance and independent t-test were used to compare within and between groups,respectively.Results:The study found significant differences in Glasgow coma scale(GCS)scores within both the nurse(F=2.78,P=0.042)and family member(F=10.27,P=0.0001)voice stimulus groups over 7 days.Comparing GCS scores between intervention groups showed significant variations before(P=0.028),during(P=0.047),and after(P=0.036)the intervention on day 7.Comparing GCS scores between the family members’voice stimulus group and the control group,significant changes were observed on days 5 and 7(P=0.043,0.030,0.030,and 0.014,0.012,0.012)before,during,and after the intervention.Conclusions:The use of beloved family members’voices proved more effective in elevating the patients’level of consciousness compared to both the nurse voice stimulus group and the control group.
基金This paper is the research result of the 2023 Undergraduate Teaching Reform Project of Higher Education in Guangxi,“Research on the Teaching Practice Model of Minority Music in Universities under the Background of Forging and Strengthening the Consciousness of the Chinese National Community”(2023JGA234).
文摘Against the strategic backdrop of forging and strengthening the consciousness of the Chinese national community in the new era,universities in border areas,as crucial platforms for the integration of multi-ethnic cultures,shoulder the significant mission of enhancing ethnic unity and promoting outstanding traditional Chinese culture.As an important carrier of Chinese culture,ethnic music not only contains profound historical memories and emotional identities but also demonstrates a powerful cultural and educational function in the teaching of border universities.Based on the actual situation of universities in border areas,this paper analyzes the unique value of ethnic music in cultivating students’national identity,cultural identity,and emotional identity,and explores effective paths for it to empower the forging and strengthening of the consciousness of the Chinese national community in teaching practice.By combining policy orientations and teaching status quo,the paper points out the main dilemmas such as single curriculum content,insufficient integration of ideological and political education,and a lack of practical resources,and proposes countermeasures such as strengthening the integration of ideological and political education,optimizing the curriculum structure,and expanding practical platforms.Through the deepening and innovation of ethnic music education,border universities can effectively enhance students’cultural consciousness and cultural confidence,providing solid educational support for forging and strengthening the consciousness of the Chinese national community.This paper has positive significance for promoting the high-quality development of education in border universities and constructing a new-era ethnic unity and progress education system.
基金supported by the Science and Technology Innovation 2030(2022ZD0205300)the International(Hong Kong,Macao,and Taiwan)Science and Technology Cooperation Project(Z221100002722014)+5 种基金the 2022 Open Project of Key Laboratory and Engineering Technology Research of the Ministry of Civil Affairs(2022GKZS0003)the Chinese Institute for Brain Research Youth Scholar Program(2022-NKX-XM-02)the Natural Science Foundation of Beijing municipality(7232049)the General Program of National Natural Science Foundation of China(82371197)the FundRef Organization name of Guarantors of Brain(HMR04170)the Royal Society(IES\R3\213123).
文摘Among the existing research on the treatment of disorders of consciousness(DOC),deep brain stimulation(DBS)offers a highly promising therapeutic approach.This comprehensive review documents the historical development of DBS and its role in the treatment of DOC,tracing its progression from an experimental therapy to a detailed modulation approach based on the mesocircuit model hypothesis.The mesocircuit model hypothesis suggests that DOC arises from disruptions in a critical network of brain regions,providing a framework for refining DBS targets.We also discuss the multimodal approaches for assessing patients with DOC,encompassing clinical behavioral scales,electrophysiological assessment,and neuroimaging techniques methods.During the evolution of DOC therapy,the segmentation of central nuclei,the recording of single-neurons,and the analysis of local field potentials have emerged as favorable technical factors that enhance the efficacy of DBS treatment.Advances in computational models have also facilitated a deeper exploration of the neural dynamics associated with DOC,linking neuron-level dynamics with macroscopic behavioral changes.Despite showing promising outcomes,challenges remain in patient selection,precise target localization,and the determination of optimal stimulation parameters.Future research should focus on conducting large-scale controlled studies to delve into the pathophysiological mechanisms of DOC.It is imperative to further elucidate the precise modulatory effects of DBS on thalamo-cortical and cortico-cortical functional connectivity networks.Ultimately,by optimizing neuromodulation strategies,we aim to substantially enhance therapeutic outcomes and greatly expedite the process of consciousness recovery in patients.
文摘This paper explores pathways for integrating the Chinese national community consciousness into ideological and political education in college English courses.Through an in-depth analysis of current teaching practices,it highlights the critical significance and urgent need for embedding this consciousness.The study proposes practical implementation strategies encompassing scientific curriculum design,in-depth content exploration,and innovative teaching methodologies.These approaches collectively facilitate the harmonious integration of knowledge transmission,skill development,and value guidance in English education.They strengthen students’identity with the Chinese national community and emotional attachment to it,while enhancing their ability to disseminate China’s cultural heritage through English communication.This framework supports the cultivation of new-era talents with both patriotic dedication and global vision.
基金supported by grants from the National Natural Science Foundation of China,No.81371194
文摘The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. However, the results were not satisfactory. In this study, we changed the constituent order of subjects＇ two-character names to create derived names. The subject＇s derived names, together with tones and their own names, were used as auditory stimuli in event-related potential experiments. Healthy controls and unconscious patients were included in this study and made to listen to these auditory stimuli. In the two paradigms, a sine tone followed by the subject＇s own name and the subject＇s derived name followed by the subject＇s own name were used as standard and deviant stimuli, respectively. The results showed that all healthy controls had the P300 using both paradigms, and that the P300 in the second paradigm had a longer latency and two peaks. All minimally conscious state patients had the P300 in the first paradigm and the majority of them had the P300 in the second paradigm. Most vegetative state patients had no P300. Patients who showed the P300 in the two paradigms had more residual consciousness, and patients with the two-peak P300 had a higher probability of awakening within a short time. Our experimental findings suggest that the P300 event-related potential could reflect the conscious state of unconscious patients.
基金supported by the Science and Technology Innovation 2030-Brain Science and Brain-Inspired Intelligence Project (2021ZD0200200)the National Natural Science Foundation of China (62327805,82151307,and 32271085)the Beijing Natural Science Foundation (5244049).
文摘When presented with visual stimuli of face images,the ventral stream visual cortex of the human brain exhibits face-specific activity that is modulated by the physical properties of the input images.However,it is still unclear whether this activity relates to conscious face perception.We explored this issue by using the human intracranial electroencephalography technique.Our results showed that face-specific activity in the ventral stream visual cortex was significantly higher when the subjects subjectively saw faces than when they did not,even when face stimuli were presented in both conditions.In addition,the face-specific neural activity exhibited a more reliable neural response and increased posterior-anterior direction information transfer in the“seen”condition than the“unseen”condition.Furthermore,the face-specific neural activity was significantly correlated with performance.These findings support the view that face-specific activity in the ventral stream visual cortex is linked to conscious face perception.
文摘Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CSB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining SST and CSB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of SST and CSB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed SST with nonconscious natural breathing for 20 min. The same participants performed SST in combination with CSB (2 s inspiratory and 4 s expiratory) for 20 min on another day. Salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: SST decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of SST and CSB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of SST and CSB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.
文摘The purpose of this study is to offer a better comprehension of what happens in organizations when enhancing organizational culture through consciousness by linking the market-oriented ecosystem variables and analyzing their relationship with a conscious organization.Design and methodology:Two questionnaires were used to test the hypotheses,the market-oriented ecosystem 38-item(Yeung&Ulrich,2019),and the conscious organization model 7-item adaptation(Sisoda,2018).Pearson correlations were calculated to measure the strength of the linear relationship among the variables involved in each one of the hypotheses,and coefficient alpha(coefficient𝛼)was used to analyze the reliability,to measure the internal consistency of the scales.Relevant findings:Context,ecosystem organizational structure,governance,and people ecosystem were positively correlated to a conscious organization.The originality of this study is based on use of the interaction among the variables of the market-oriented ecosystem model(continuous changing context,ecosystem organizational structure,governance,and people ecosystem)and a conscious organizational culture.Finally,the practical implications of having high levels of the market-oriented ecosystem variables predict high level of consciousness in organizations.These variables require careful consideration,a proactive planning process to enhance organizational culture through consciousness.
文摘This article explores the intersection of the Eight-Circuit Model of Consciousness (ECM), initially conceptualized by Timothy Leary and expanded by Robert Anton Wilson, and its implications for mind-body health. By analyzing each circuit’s role in human consciousness, we discuss how activating and balancing these circuits can lead to enhanced psychological well-being, stress reduction, and overall physical health. Recent research is integrated to provide a contemporary understanding of how the ECM can be applied to modern mind-body therapies, with a focus on both theoretical implications and practical applications.
文摘A prestigious conference claimed recently a revolution in neuroscience to understand consciousness.In this paper it is shown that this revolution already came,revealing the determinant role of information for human and living structures,both for their structuration and behavior,explaining consciousness at human as the result of the activity of the Informational System of Human and Living Structures.For this,it is emphasized and discussed the informational structure of the eukaryotic cell,the basic/representative composing unit of the multicellular body of human,animals,and plants,showing that the composition and functions of the informational system are basically similar with that of human.To reveal the driving role of informational mechanisms in human and subhuman organisms,it is introduced the concept of matter-related information,showing that information can be hidden/“embodied”or released/“disembodied”in or from the elemental micro/macro components of the body,during the multiple chain/cascade interactions including transduction processes.It is shown that such interactions are initiated from two main categories of informational sources:implicit(genetic)and explicit(external/internal)sources,the first category leading to structuration of the body and the second the reactive behavior.Consciousness in human and subhuman organisms,expressed by two corresponding informational relations,is the result of the release of information by the mind,acting as an informational operator/device,the development degree of mind and consciousness depending on the complexity degree and adaptation.An analogy of this Informational Model of Human and Living Structures(IMHLS)with the ancient model of chakras is highlighted,showing that these models support each other,applied with beneficial effects in Reiki technique and music-based cognitive multi-task therapy for neuro-rehabilitation.
文摘Purpose:What factors influence conscious consumerism,especially related to race and gender identities?This scholarship explores three white women-led social responsibility organizations’(SROs)aspirations to encourage conscious consumerism as well as factors that influence conscious consumerism.Design/methodology/approach:Using the Black feminist thought and sustainability development theory,the data were analyzed using a thematic analysis to explore the activation of the white savior industrial complex(WSIC)in SROs.Interviews provided in-depth knowledge of the SRO culture including,but not limited to,insight on social exclusion and partnerships.Findings:Noonday Collection,Sseko Designs,and Trades of Hope,all SROs,aspire to be dedicated to people,planet,and profit and encourage conscious consumerism as a means for their customer base and sales consultants to“do their part”,and yet,an unintended consequence of the SROs’work is social exclusion and white saviorism.Originality:This scholarship investigates what can be done to dismantle the overreliance of conscious consumerism in an effort to finally strip white saviorism,and its role in the white savior industrial complex(WSIC),of its power.
文摘This work explores the axiology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory(CFT)within the larger body of contemporary ontological debates regarding the nature,origin,and constitution of consciousness in the universe.The work goes on to highlight the manifestation of Mocombe’s consciousness field in the material resource framework that is the earth,and the nature and origins of ethics and values.
文摘This work explores the epistemology of consciousness in Mocombe’s consciousness field in the material world.The paper critically assesses Mocombe’s consciousness field theory within the larger body of contemporary ontological debates regarding the nature,origin,and constitution of consciousness in the universe.The work goes on to highlight the manifestation of Mocombe’s consciousness field from the absolute vacuum to and in the material resource framework that is the earth,and how we come to know about and experience both(the absolute vacuum and the material worlds that it creates).
