With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extract...With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks.展开更多
Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important featu...Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important features of modern aircraft design. This paper explores the effects of commonality on different aircraft models in a commercial aircraft family. The existing product commonality indexes are summarized and their limitations in the application to aircraft design are discussed. Then a new component commonality index is proposed based on the component decomposition structure. A model for calculating the aircraft program value is established,which considers development costs, manufacturing costs, sale price, operation costs and residual costs. The effects of aircraft commonality on time and economic costs of both development and manufacturing, and on sale price, are analyzed and quantified. The commonality evaluation strategy is obtained, which features comprehensive consideration of the aircraft program value and time costs. The break-even analysis of aircraft is proceeded on the basis of costs and price data. By using a real option method, the strategy considers the uncertainty of the aircraft program and the flexibility of the manufacturer. This strategy proves to be rational and applicable to aircraft design based on the calculation of three examples and the analysis of parameter sensitivity.展开更多
It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different pro...It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different products is a vital method of accomplishing this goal.The advantages of using a common process in production are stated in the literature.However,the mathematical models as well as simulation or conceptual models are not sufficient.The main objective of this paper is to develop mathematical models for multiproduct and multistage production under quality and breakdown uncertainties.The idea of the process commonality is incorporated in the proposed models.The models are validated by primary data collected from a Malaysian company and comparison of the timely requirement schedules of earlier MRP II and the proposed models under stable and perfect production environments.An appreciable convergence of the outcomes is observed.However,the proposed models are carrying additional information about the available locations of the parts in a time frame.After validation,the effects of process commonality on cost,capacity and the requirement schedule under uncertainties are examined.It is observed that the use of common processes in manufacturing is always better than the non-commonality scenario in terms of production cost.However,the increase in capacity requirement for commonality designs is higher for an ideal system,while it is less when the system suffers from breakdowns and a quality problem.展开更多
Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists ...Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists redundancy among the spectrum data collected by a sensor node within a data collection period,which may reduce the data uploading efficiency.In this paper,we investigate the inter-data commonality detection which describes how much two data have in common.We define common segment set and divide it into six categories firstly,then a method to measure a common segment set is conducted by extracting commonality between two files.Moreover,the existing algorithms fail in finding a good common segment set,so Common Data Measurement(CDM)algorithm that can identify a good common segment set based on inter-data commonality detection is proposed.Theoretical analysis proves that CDM algorithm achieves a good measurement for the commonality between two strings.In addition,we conduct an synthetic dataset which are produced randomly.Numerical results shows that CDM algorithm can get better performance in measuring commonality between two binary files compared with Greedy-String-Tiling(GST)algorithm and simple greedy algorithm.展开更多
In the science fiction novel titled The Planet of the Apes (1963), Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small...In the science fiction novel titled The Planet of the Apes (1963), Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small group of people is totally embarrassed and confused by observing this strange world. On the planet of the apes that they have discovered, it is the apes that are more intelligent than the humans. On the earth, it was the other way around. That observation results in their perplexity. The two communities, human and simian, bear with one another the relationship that corresponds to what Lotman calls "enantiomorphic pairings". In this context, a series of questions deserves to be raised: Is a "common language" possible between the two communities in the enantiomorphic pairings? If the answer is yes, under what conditions could they succeed in opening up a space where they can have something in common? In rereading The Planet of the Apes with reference to Lotman's semiotics of culture, we would like to formulate a response to those questions. Our claim is that the experience of finitude of one's own language can make possible an access to the new form of universality requisite for the cross-cultural communication: commonality without common points.展开更多
The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. How...The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. However, the existing estimating model for the R&D cost of civil aircraft ignores the effects of common design, so the value estimated by estimating derivative models is significantly inconsistent with the actual one. To solve this problem, a novel assessment method for civil aircraft commonality indicators is developed based on fuzzy set in the present study, exploiting the attributes and structural parameters of the aircraft to be assessed as input to determine the degree of membership that pertains to the commonality sub-interval as the commonality indicator.Then the BP(Back Propagation) neural network algorithm is adopted to establish the relationship between the common index and the decrease rate of the R&D cost of derivative models. The model employs over a dozen typical civil aircraft models(e.g., Boeing, Airbus, and Bombardier) as the sample data for network learning training to build a mature neural network model for estimating the R&D cost of novel derivative models. As revealed from the comparative analysis on the calculated results of the samples, the estimated results of the model given the effects of commonality in the present study exhibit higher estimation accuracy and value for future work.展开更多
The recent rapid development in information systems(ISs)has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains,using specific commonalities.However,stovepipe ...The recent rapid development in information systems(ISs)has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains,using specific commonalities.However,stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders.So far,there has been no research on an enterprise architecture framework(EAF)that can satisfy with the coefficient factors of system architecture(SA)and enterprise architecture(EA).This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features.EAFoC(Enterprise Architecture Framework based on Commonality)is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology(IT)domain.Thus,it should be possible to integrate an established heterogeneous framework for each stakeholder's view.Consequently,the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture,smooth communication among stakeholders,systematic integration management of diversified and complicated new IT technologies,interoperability among heterogeneous ISs,and reusability based on commonality with other platforms.展开更多
Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear u...Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.展开更多
This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The pur...This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The purpose is to assist product deisgn teams to make rational decisions in assigning unique parts or pursuing component standardization. In order to enhance the usability of the model, approximations are made to simplify the model and calculations.展开更多
China’s“common prosperity”policy is a multidimensional pursuit of social and economic progress aimed at full realization by 2050.A CHIEVING common prosperity–prosperity that is universally shared–has been a longs...China’s“common prosperity”policy is a multidimensional pursuit of social and economic progress aimed at full realization by 2050.A CHIEVING common prosperity–prosperity that is universally shared–has been a longstanding aspiration of the Chinese government.展开更多
Recent evidence suggests that ferroptosis plays a crucial role in the occurrence and development of white matter lesions.However,the mechanisms and regulatory pathways involved in ferroptosis within white matter lesio...Recent evidence suggests that ferroptosis plays a crucial role in the occurrence and development of white matter lesions.However,the mechanisms and regulatory pathways involved in ferroptosis within white matter lesions remain unclear.Long non-coding RNAs(lnc RNAs)have been shown to influence the occurrence and development of these lesions.We previously identified lnc_011797 as a biomarker of white matter lesions by high-throughput sequencing.To investigate the mechanism by which lnc_011797 regulates white matter lesions,we established subjected human umbilical vein endothelial cells to oxygenglucose deprivation to simulate conditions associated with white matter lesions.The cells were transfected with lnc_011797 overexpression or knockdown lentiviruses.Our findings indicate that lnc_011797 promoted ferroptosis in these cells,leading to the formation of white matter lesions.Furthermore,lnc_011797 functioned as a competitive endogenous RNA(ce RNA)for mi R-193b-3p,thereby regulating the expression of WNK1 and its downstream ferroptosis-related proteins.To validate the role of lnc_011797 in vivo,we established a mouse model of white matter lesions through bilateral common carotid artery stenosis.The results from this model confirmed that lnc_011797 regulates ferroptosis via WNK1 and promotes the development of white matter lesions.These findings clarify the mechanism by which lnc RNAs regulate white matter lesions,providing a new target for the diagnosis and treatment of white matter lesions.展开更多
One crucial measure of strengthening and advancing the Party's work on ethnic affairs in the new era is to promote interaction,communication and integration of various ethnic groups,so as to enhance commonality.En...One crucial measure of strengthening and advancing the Party's work on ethnic affairs in the new era is to promote interaction,communication and integration of various ethnic groups,so as to enhance commonality.Entering the new era,Inner Mongolia,Guangxi and Ningxia have achieved remarkable results in encouraging interaction,communication and integration of various ethnic groups.By comparatively analyzing successes of the three autonomous regions through the perspective of promoting commonality,this article summarizes the following strategic revelations:1)we should comprehensively implement the Party's ethnic policies and ensure theactual implementation of mutual interaction,mutual communication and mutual integration of ethnic groups;2)we should proactively promote the substantial progress of the economy,so as to provide solid material foundation for mutual interaction,mutual communication and mutual integration of ethnic groups;3)we should facilitate activities that promote ethnic unity and progress,so that the promotion of interaction,communication and mutual integration of ethnic groups can be seen,be felt and gain actual outcomes;4)we should take measures that suit to local conditions and explore all-round embedding mechanisms in order to foster the ethos for mutual interaction,mutual communication and mutual integration of ethnic groups;5)we should make every effort to forge a strong sense of community for the Chinese nation and orient precisely to the cause of encouraging mutual interaction,mutual communication and mutual integration of ethnic groups.展开更多
The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effecti...The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effective against one group of viruses and there is a need for a non-specific treatment that can be used against all respiratory viruses. Carrageenan is a general term used to describe a range of sulfated polysaccharides extracted from edible seaweeds. Large polyanionic molecules such as carrageenan have been shown to have antiviral activity against a wide range of viruses in vitro. The strong anionic charge of carrageenan attracts and traps viruses that have positively charged areas on their surface. The trapped viruses are then unable to infect epithelial cells. Iota-carrageenan exerts its’ antiviral activity by physical means due to its high anionic charge and it does not have any pharmacological properties and therefore does not have any toxicology or known side effects from treatment. Iota-carrageenan does not have any taste or smell and, when used as a nasal spray, does not have any adverse effects. Iota-carrageenan is an ideal prophylactic treatment for the common cold and is safe for use in children. Treatment of common cold with iota-carrageenan has to date been studied in five placebo-controlled clinical trials and these trials support both efficacy as a prophylactic treatment for colds and the safety and tolerability of iota-carrageenan.展开更多
Ulcerative colitis has baffled researchers since the early 20th century.The pre-vailing explanation attributes the chronic recurring episodes of bloody diarrhea and abdominal pain to some form of immune abnormality,de...Ulcerative colitis has baffled researchers since the early 20th century.The pre-vailing explanation attributes the chronic recurring episodes of bloody diarrhea and abdominal pain to some form of immune abnormality,despite the lack of supporting evidence.This highlights the critical need for innovative research directions and methodologies to uncover the cause and develop a cure for this disease.By analyzing existing data from less than a dozen previously published studies,a novel,evidence-based pathogenesis was constructed,implicating colonic epithelial hydrogen peroxide as a causal factor in the development of this disease.This newly identified mechanism informed the creation of a ground-breaking class of therapeutics,known as reducing agents,which have demon-strated remarkable success in resolving colonic inflammation and restoring colonic health in patients with refractory ulcerative colitis.This paper outlines the timeline of these publications and reinterprets the findings within the context of contemporary biomedical science.展开更多
Reconfigurable intelligent surface(RIS)is a novel meta-material which can form a smart radio environment by dynamically altering reflection directions of the impinging electromagnetic waves.In the prior literature,the...Reconfigurable intelligent surface(RIS)is a novel meta-material which can form a smart radio environment by dynamically altering reflection directions of the impinging electromagnetic waves.In the prior literature,the inter-RIS links which also contribute to the performance of the whole system are usually neglected when multiple RISs are deployed.In this paper we investigate a general double-RIS assisted multiple-input multiple-output(MIMO)wireless communication system under spatially correlated non line-of-sight propagation channels,where the cooperation of the double RISs is also considered.The design objective is to maximize the achievable ergodic rate based on full statistical channel state information(CSI).Specifically,we firstly present a closedform asymptotic expression for the achievable ergodic rate by utilizing replica method from statistical physics.Then a full statistical CSI-enabled optimal design is proposed which avoids high pilot training overhead compared to instantaneous CSI-enabled design.To further reduce the signal processing overhead and lower the complexity for practical realization,a common-phase scheme is proposed to design the double RISs.Simulation results show that the derived asymptotic ergodic rate is quite accurate even for small-sized antenna arrays.And the proposed optimization algorithm can achieve substantial gain at the expense of a low overhead and complexity.Furthermore,the cooperative double-RIS assisted MIMO framework is proven to achieve superior ergodic rate performance and high communication reliability under harsh propagation environment.展开更多
BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a ...BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a result of pancreaticobiliary reflux.Roux-en-Y choledochojejunostomy is a common surgical method for the treatment of PBM,but there are several associated complications that may occur after this operation.CASE SUMMARY The patient,a 12-year-old female,was hospitalized nearly 20 times in 2021 for recurrent acute pancreatitis.In 2022,she was diagnosed with PBM and underwent laparoscopic common bile duct resection and Roux-en-Y choledochojejunostomy in a tertiary hospital.In the first year after surgery,the patient had more than 10 recurrent acute pancreatitis episodes.After undergoing abdominal computed tomography and other examinations,she was diagnosed with“residual bile duct stones and recurrent acute pancreatitis”.On January 30,2024,the patient was admitted to our hospital due to recurrent upper abdominal pain and was cured through endoscopic retrograde cholangiopancreatography.CONCLUSION This article reports a case of a child with distal residual common bile duct stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy for PBM.The patient was cured through endoscopic retrograde cholangiopancreatography.展开更多
BACKGROUND Common bile duct stones pose a high risk of recurrence or disease progression if not promptly treated.However,there is still no optimal treatment approach.AIM To investigate the clinical efficacy of modifie...BACKGROUND Common bile duct stones pose a high risk of recurrence or disease progression if not promptly treated.However,there is still no optimal treatment approach.AIM To investigate the clinical efficacy of modified pancreatic duct stent drainage in endoscopic retrograde cholangiopancreatography(ERCP)for treating common bile duct stones.METHODS This retrospective study included 175 patients with common bile duct stones treated at Taizhou Fourth People’s Hospital between January 1,2021,and November 30,2023.The patients were divided into three groups-the modified pancreatic duct stent drainage group(59 cases),the nasobiliary drainage group(58 cases),and the standard biliary drainage group(58 cases).Preoperative general clinical data,laboratory indicators,and the visual analog scale(VAS)at two time points(24 hours before and after surgery)were compared,along with postoperative complications across the three groups.RESULTS Serum levels of aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase,gamma-glutamyltransferase,total bilirubin,direct bilirubin,Creactive protein,and amylase were significantly lower in the modified pancreatic duct stent drainage group and the standard biliary drainage group than those in the nasobiliary drainage group(P<0.05).However,no statistically significant differences were observed in white blood cells,hemoglobin,or neutrophil levels among the three groups(P>0.05).The standard biliary drainage group had significantly lower VAS scores[(4.36±1.18)points]than those for the modified pancreatic duct stent drainage group[(4.92±1.68)points](P=0.033),and the nasobiliary drainage group[(5.54±1.24)points](P=0.017).There were no statistically significant differences in complication rates across the three groups(P>0.05).CONCLUSION Compared to standard biliary drainage and nasobiliary drainage,the modified pancreatic duct stent used during ERCP for patients with bile duct stones significantly reduced hepatocyte injury,improved liver function parameters,alleviated inflammation and pain,enhanced patient comfort,and demonstrated superior safety.展开更多
In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main re...In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main results generalize and extend several well-known comparable results from the existing literature.Moreover,some examples are provided to illustrate the main results.展开更多
基金supported by the Natural Science Foundation of Henan under Grant 242300421220the Henan Provincial Science and Technology Research Project under Grants 252102211047 and 252102211062+3 种基金the Jiangsu Provincial Scheme Double Initiative Plan JSS-CBS20230474the XJTLU RDF-21-02-008the Science and Technology Innovation Project of Zhengzhou University of Light Industry under Grant 23XNKJTD0205the Higher Education Teaching Reform Research and Practice Project of Henan Province under Grant 2024SJGLX0126.
文摘With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks.
文摘Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important features of modern aircraft design. This paper explores the effects of commonality on different aircraft models in a commercial aircraft family. The existing product commonality indexes are summarized and their limitations in the application to aircraft design are discussed. Then a new component commonality index is proposed based on the component decomposition structure. A model for calculating the aircraft program value is established,which considers development costs, manufacturing costs, sale price, operation costs and residual costs. The effects of aircraft commonality on time and economic costs of both development and manufacturing, and on sale price, are analyzed and quantified. The commonality evaluation strategy is obtained, which features comprehensive consideration of the aircraft program value and time costs. The break-even analysis of aircraft is proceeded on the basis of costs and price data. By using a real option method, the strategy considers the uncertainty of the aircraft program and the flexibility of the manufacturer. This strategy proves to be rational and applicable to aircraft design based on the calculation of three examples and the analysis of parameter sensitivity.
文摘It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different products is a vital method of accomplishing this goal.The advantages of using a common process in production are stated in the literature.However,the mathematical models as well as simulation or conceptual models are not sufficient.The main objective of this paper is to develop mathematical models for multiproduct and multistage production under quality and breakdown uncertainties.The idea of the process commonality is incorporated in the proposed models.The models are validated by primary data collected from a Malaysian company and comparison of the timely requirement schedules of earlier MRP II and the proposed models under stable and perfect production environments.An appreciable convergence of the outcomes is observed.However,the proposed models are carrying additional information about the available locations of the parts in a time frame.After validation,the effects of process commonality on cost,capacity and the requirement schedule under uncertainties are examined.It is observed that the use of common processes in manufacturing is always better than the non-commonality scenario in terms of production cost.However,the increase in capacity requirement for commonality designs is higher for an ideal system,while it is less when the system suffers from breakdowns and a quality problem.
基金supported in part by the National Natural Science Foundation of China(No.61901328)the China Postdoctoral Science Foundation (No. 2019M653558)+1 种基金the Fundamental Research Funds for the Central Universities (No. CJT150101)the Key project of National Natural Science Foundation of China (No. 61631015)
文摘Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists redundancy among the spectrum data collected by a sensor node within a data collection period,which may reduce the data uploading efficiency.In this paper,we investigate the inter-data commonality detection which describes how much two data have in common.We define common segment set and divide it into six categories firstly,then a method to measure a common segment set is conducted by extracting commonality between two files.Moreover,the existing algorithms fail in finding a good common segment set,so Common Data Measurement(CDM)algorithm that can identify a good common segment set based on inter-data commonality detection is proposed.Theoretical analysis proves that CDM algorithm achieves a good measurement for the commonality between two strings.In addition,we conduct an synthetic dataset which are produced randomly.Numerical results shows that CDM algorithm can get better performance in measuring commonality between two binary files compared with Greedy-String-Tiling(GST)algorithm and simple greedy algorithm.
文摘In the science fiction novel titled The Planet of the Apes (1963), Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small group of people is totally embarrassed and confused by observing this strange world. On the planet of the apes that they have discovered, it is the apes that are more intelligent than the humans. On the earth, it was the other way around. That observation results in their perplexity. The two communities, human and simian, bear with one another the relationship that corresponds to what Lotman calls "enantiomorphic pairings". In this context, a series of questions deserves to be raised: Is a "common language" possible between the two communities in the enantiomorphic pairings? If the answer is yes, under what conditions could they succeed in opening up a space where they can have something in common? In rereading The Planet of the Apes with reference to Lotman's semiotics of culture, we would like to formulate a response to those questions. Our claim is that the experience of finitude of one's own language can make possible an access to the new form of universality requisite for the cross-cultural communication: commonality without common points.
文摘The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. However, the existing estimating model for the R&D cost of civil aircraft ignores the effects of common design, so the value estimated by estimating derivative models is significantly inconsistent with the actual one. To solve this problem, a novel assessment method for civil aircraft commonality indicators is developed based on fuzzy set in the present study, exploiting the attributes and structural parameters of the aircraft to be assessed as input to determine the degree of membership that pertains to the commonality sub-interval as the commonality indicator.Then the BP(Back Propagation) neural network algorithm is adopted to establish the relationship between the common index and the decrease rate of the R&D cost of derivative models. The model employs over a dozen typical civil aircraft models(e.g., Boeing, Airbus, and Bombardier) as the sample data for network learning training to build a mature neural network model for estimating the R&D cost of novel derivative models. As revealed from the comparative analysis on the calculated results of the samples, the estimated results of the model given the effects of commonality in the present study exhibit higher estimation accuracy and value for future work.
文摘The recent rapid development in information systems(ISs)has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains,using specific commonalities.However,stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders.So far,there has been no research on an enterprise architecture framework(EAF)that can satisfy with the coefficient factors of system architecture(SA)and enterprise architecture(EA).This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features.EAFoC(Enterprise Architecture Framework based on Commonality)is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology(IT)domain.Thus,it should be possible to integrate an established heterogeneous framework for each stakeholder's view.Consequently,the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture,smooth communication among stakeholders,systematic integration management of diversified and complicated new IT technologies,interoperability among heterogeneous ISs,and reusability based on commonality with other platforms.
文摘Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.
文摘This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The purpose is to assist product deisgn teams to make rational decisions in assigning unique parts or pursuing component standardization. In order to enhance the usability of the model, approximations are made to simplify the model and calculations.
文摘China’s“common prosperity”policy is a multidimensional pursuit of social and economic progress aimed at full realization by 2050.A CHIEVING common prosperity–prosperity that is universally shared–has been a longstanding aspiration of the Chinese government.
基金supported by the Qingdao Medical Health Research Project,No.2023-WJZD212(to XX)。
文摘Recent evidence suggests that ferroptosis plays a crucial role in the occurrence and development of white matter lesions.However,the mechanisms and regulatory pathways involved in ferroptosis within white matter lesions remain unclear.Long non-coding RNAs(lnc RNAs)have been shown to influence the occurrence and development of these lesions.We previously identified lnc_011797 as a biomarker of white matter lesions by high-throughput sequencing.To investigate the mechanism by which lnc_011797 regulates white matter lesions,we established subjected human umbilical vein endothelial cells to oxygenglucose deprivation to simulate conditions associated with white matter lesions.The cells were transfected with lnc_011797 overexpression or knockdown lentiviruses.Our findings indicate that lnc_011797 promoted ferroptosis in these cells,leading to the formation of white matter lesions.Furthermore,lnc_011797 functioned as a competitive endogenous RNA(ce RNA)for mi R-193b-3p,thereby regulating the expression of WNK1 and its downstream ferroptosis-related proteins.To validate the role of lnc_011797 in vivo,we established a mouse model of white matter lesions through bilateral common carotid artery stenosis.The results from this model confirmed that lnc_011797 regulates ferroptosis via WNK1 and promotes the development of white matter lesions.These findings clarify the mechanism by which lnc RNAs regulate white matter lesions,providing a new target for the diagnosis and treatment of white matter lesions.
文摘One crucial measure of strengthening and advancing the Party's work on ethnic affairs in the new era is to promote interaction,communication and integration of various ethnic groups,so as to enhance commonality.Entering the new era,Inner Mongolia,Guangxi and Ningxia have achieved remarkable results in encouraging interaction,communication and integration of various ethnic groups.By comparatively analyzing successes of the three autonomous regions through the perspective of promoting commonality,this article summarizes the following strategic revelations:1)we should comprehensively implement the Party's ethnic policies and ensure theactual implementation of mutual interaction,mutual communication and mutual integration of ethnic groups;2)we should proactively promote the substantial progress of the economy,so as to provide solid material foundation for mutual interaction,mutual communication and mutual integration of ethnic groups;3)we should facilitate activities that promote ethnic unity and progress,so that the promotion of interaction,communication and mutual integration of ethnic groups can be seen,be felt and gain actual outcomes;4)we should take measures that suit to local conditions and explore all-round embedding mechanisms in order to foster the ethos for mutual interaction,mutual communication and mutual integration of ethnic groups;5)we should make every effort to forge a strong sense of community for the Chinese nation and orient precisely to the cause of encouraging mutual interaction,mutual communication and mutual integration of ethnic groups.
文摘The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effective against one group of viruses and there is a need for a non-specific treatment that can be used against all respiratory viruses. Carrageenan is a general term used to describe a range of sulfated polysaccharides extracted from edible seaweeds. Large polyanionic molecules such as carrageenan have been shown to have antiviral activity against a wide range of viruses in vitro. The strong anionic charge of carrageenan attracts and traps viruses that have positively charged areas on their surface. The trapped viruses are then unable to infect epithelial cells. Iota-carrageenan exerts its’ antiviral activity by physical means due to its high anionic charge and it does not have any pharmacological properties and therefore does not have any toxicology or known side effects from treatment. Iota-carrageenan does not have any taste or smell and, when used as a nasal spray, does not have any adverse effects. Iota-carrageenan is an ideal prophylactic treatment for the common cold and is safe for use in children. Treatment of common cold with iota-carrageenan has to date been studied in five placebo-controlled clinical trials and these trials support both efficacy as a prophylactic treatment for colds and the safety and tolerability of iota-carrageenan.
文摘Ulcerative colitis has baffled researchers since the early 20th century.The pre-vailing explanation attributes the chronic recurring episodes of bloody diarrhea and abdominal pain to some form of immune abnormality,despite the lack of supporting evidence.This highlights the critical need for innovative research directions and methodologies to uncover the cause and develop a cure for this disease.By analyzing existing data from less than a dozen previously published studies,a novel,evidence-based pathogenesis was constructed,implicating colonic epithelial hydrogen peroxide as a causal factor in the development of this disease.This newly identified mechanism informed the creation of a ground-breaking class of therapeutics,known as reducing agents,which have demon-strated remarkable success in resolving colonic inflammation and restoring colonic health in patients with refractory ulcerative colitis.This paper outlines the timeline of these publications and reinterprets the findings within the context of contemporary biomedical science.
基金supported in part by the Xi’an Jiaotong-Liverpool University(XJTLU)Research Development Fund(2024–2027)under Grant RDF-23-02-010supported in part by the Guangdong Basic and Applied Basic Research Foundation under Grant 2023A1515110732+5 种基金supported in part by the National Natural Science Foundation of China(NSFC)under Grant 62071247supported in part by the Science and Technology Development Fund,Macao,China SAR under Grants 0087/2022/AFJ and 001/2024/SKLin part by the National Natural Science Foundation of China under Grant 62261160650in part by the Research Committee of University of Macao,Macao SAR,China under Grants MYRG-GRG2023-00116-FST-UMDF and MYRG2020-00095-FSTsupported in part by the NSFC under Grant 62261160576 and 62301148in part by the Fundamental Research Funds for the Central Universities under Grant 2242023K5003.
文摘Reconfigurable intelligent surface(RIS)is a novel meta-material which can form a smart radio environment by dynamically altering reflection directions of the impinging electromagnetic waves.In the prior literature,the inter-RIS links which also contribute to the performance of the whole system are usually neglected when multiple RISs are deployed.In this paper we investigate a general double-RIS assisted multiple-input multiple-output(MIMO)wireless communication system under spatially correlated non line-of-sight propagation channels,where the cooperation of the double RISs is also considered.The design objective is to maximize the achievable ergodic rate based on full statistical channel state information(CSI).Specifically,we firstly present a closedform asymptotic expression for the achievable ergodic rate by utilizing replica method from statistical physics.Then a full statistical CSI-enabled optimal design is proposed which avoids high pilot training overhead compared to instantaneous CSI-enabled design.To further reduce the signal processing overhead and lower the complexity for practical realization,a common-phase scheme is proposed to design the double RISs.Simulation results show that the derived asymptotic ergodic rate is quite accurate even for small-sized antenna arrays.And the proposed optimization algorithm can achieve substantial gain at the expense of a low overhead and complexity.Furthermore,the cooperative double-RIS assisted MIMO framework is proven to achieve superior ergodic rate performance and high communication reliability under harsh propagation environment.
文摘BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a result of pancreaticobiliary reflux.Roux-en-Y choledochojejunostomy is a common surgical method for the treatment of PBM,but there are several associated complications that may occur after this operation.CASE SUMMARY The patient,a 12-year-old female,was hospitalized nearly 20 times in 2021 for recurrent acute pancreatitis.In 2022,she was diagnosed with PBM and underwent laparoscopic common bile duct resection and Roux-en-Y choledochojejunostomy in a tertiary hospital.In the first year after surgery,the patient had more than 10 recurrent acute pancreatitis episodes.After undergoing abdominal computed tomography and other examinations,she was diagnosed with“residual bile duct stones and recurrent acute pancreatitis”.On January 30,2024,the patient was admitted to our hospital due to recurrent upper abdominal pain and was cured through endoscopic retrograde cholangiopancreatography.CONCLUSION This article reports a case of a child with distal residual common bile duct stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy for PBM.The patient was cured through endoscopic retrograde cholangiopancreatography.
文摘BACKGROUND Common bile duct stones pose a high risk of recurrence or disease progression if not promptly treated.However,there is still no optimal treatment approach.AIM To investigate the clinical efficacy of modified pancreatic duct stent drainage in endoscopic retrograde cholangiopancreatography(ERCP)for treating common bile duct stones.METHODS This retrospective study included 175 patients with common bile duct stones treated at Taizhou Fourth People’s Hospital between January 1,2021,and November 30,2023.The patients were divided into three groups-the modified pancreatic duct stent drainage group(59 cases),the nasobiliary drainage group(58 cases),and the standard biliary drainage group(58 cases).Preoperative general clinical data,laboratory indicators,and the visual analog scale(VAS)at two time points(24 hours before and after surgery)were compared,along with postoperative complications across the three groups.RESULTS Serum levels of aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase,gamma-glutamyltransferase,total bilirubin,direct bilirubin,Creactive protein,and amylase were significantly lower in the modified pancreatic duct stent drainage group and the standard biliary drainage group than those in the nasobiliary drainage group(P<0.05).However,no statistically significant differences were observed in white blood cells,hemoglobin,or neutrophil levels among the three groups(P>0.05).The standard biliary drainage group had significantly lower VAS scores[(4.36±1.18)points]than those for the modified pancreatic duct stent drainage group[(4.92±1.68)points](P=0.033),and the nasobiliary drainage group[(5.54±1.24)points](P=0.017).There were no statistically significant differences in complication rates across the three groups(P>0.05).CONCLUSION Compared to standard biliary drainage and nasobiliary drainage,the modified pancreatic duct stent used during ERCP for patients with bile duct stones significantly reduced hepatocyte injury,improved liver function parameters,alleviated inflammation and pain,enhanced patient comfort,and demonstrated superior safety.
基金Supported by the National Natural Science Foundation of China(12001249)the Natural Science Foundation of Jiangxi Province(20232BAB211004)the Educational Commission Science Programm of Jiangxi Province(GJJ2200523)。
文摘In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main results generalize and extend several well-known comparable results from the existing literature.Moreover,some examples are provided to illustrate the main results.