Aiming at the shortcomings of traditional contact measurement methods such as low measurement efficiency,high cost and low accuracy,a non-contact optical measurement method based on the laser displacement sensor is pr...Aiming at the shortcomings of traditional contact measurement methods such as low measurement efficiency,high cost and low accuracy,a non-contact optical measurement method based on the laser displacement sensor is proposed.According to the relevant regulations of the coaxiality error evaluation standard and the structural characteristics of the compound gear shaft,we have designed and built a set of supporting software system as well as a hardware test platform.In this paper,the distance difference threshold and scale threshold methods are used to eliminate outlier data.The least squares circle is selected to calculate the center of the circle and the minimum containment cylinder axis method is used as the reference axis of the composite gear shaft.Compensated by the standard step shaft calibration,the coaxiality error of the composite gear shaft can be measured to be within 0.01 mm in less than two minutes.The range value of the multi-section measurement test is 0.065 mm.The average coaxiality error is∅0.476 mm.展开更多
Fluorescence imaging in the second near-infrared window(NIR-II,900-1880 nm)offers high signalto-background ratio(SBR),enhanced definition,and superior tissue penetration,making it ideal for real-time surgical navigati...Fluorescence imaging in the second near-infrared window(NIR-II,900-1880 nm)offers high signalto-background ratio(SBR),enhanced definition,and superior tissue penetration,making it ideal for real-time surgical navigation.However,with single-channel imaging,surgeons must frequently switch between the surgi⁃cal field and the NIR-II images on the monitor.To address this,a coaxial dual-channel imaging system that com⁃bines visible light and 1100 nm longpass(1100LP)fluorescence was developed.The system features a custom⁃ized coaxial dual-channel lens with optimized distortion,achieving precise alignment with an error of less than±0.15 mm.Additionally,the shared focusing mechanism simplifies operation.Using FDA-approved indocya⁃nine green(ICG),the system was successfully applied in dual-channel guided rat lymph node excision,and blood supply assessment of reconstructed human flap.This approach enhances surgical precision,improves opera⁃tional efficiency,and provides a valuable reference for further clinical translation of NIR-II fluorescence imaging.展开更多
To reduce the vibration of the Coaxial Helicopter Main Transmission System(CHMTS)considering both level and vertical flight conditions,a vibration evaluation and optimization model for the CHMTS was built.The vibratio...To reduce the vibration of the Coaxial Helicopter Main Transmission System(CHMTS)considering both level and vertical flight conditions,a vibration evaluation and optimization model for the CHMTS was built.The vibration simulation model of the CHMTS was set up by gear dynamics theory and loaded contact analysis.For better evaluation of the system vibration,a vibration evaluation method for the CHMTS was established by the G1 method-variation coefficient method.A hybrid Gravitational Search Algorithm-Simulated Annealing(GSA-SA)algorithm was combined to balance convergence speed and searching accuracy.The principle test was conducted to prove the accuracy of theoretical method,in which the maximum relative error is16.26%.The optional results show that the vibration of the optimized transmission system decreases significantly,in which the maximum reduction of key vibration indicators reaches more than 20%.The theoretical results have been compared to the experiment to verify the effectiveness of the vibration optimization method.The proposed method could be extended to other fields.展开更多
The packaging quality of coaxial laser diodes(CLDs)plays a pivotal role in determining their optical performance and long-term reliability.As the core packaging process,high-precision laser welding requires precise co...The packaging quality of coaxial laser diodes(CLDs)plays a pivotal role in determining their optical performance and long-term reliability.As the core packaging process,high-precision laser welding requires precise control of process parameters to suppress optical power loss.However,the complex nonlinear relationship between welding parameters and optical power loss renders traditional trial-and-error methods inefficient and imprecise.To address this challenge,a physics-informed(PI)and data-driven collaboration approach for welding parameter optimization is proposed.First,thermal-fluid-solid coupling finite element method(FEM)was employed to quantify the sensitivity of welding parameters to physical characteristics,including residual stress.This analysis facilitated the identification of critical factors contributing to optical power loss.Subsequently,a Gaussian process regression(GPR)model incorporating finite element simulation prior knowledge was constructed based on the selected features.By introducing physics-informed kernel(PIK)functions,stress distribution patterns were embedded into the prediction model,achieving high-precision optical power loss prediction.Finally,a Bayesian optimization(BO)algorithm with an adaptive sampling strategy was implemented for efficient parameter space exploration.Experimental results demonstrate that the proposedmethod effectively establishes explicit physical correlations between welding parameters and optical power loss.The optimized welding parameters reduced optical power loss by 34.1%,providing theoretical guidance and technical support for reliable CLD packaging.展开更多
The measurement of low-level radioactivity using high-purity germanium(HPGe)detectors is important in applications such as environmental background radiation,material screening,and rare decays.The dead layers,dead zon...The measurement of low-level radioactivity using high-purity germanium(HPGe)detectors is important in applications such as environmental background radiation,material screening,and rare decays.The dead layers,dead zones,aluminum shell thickness,and diameter of Ge crystals are the most influential factors affecting the performance of HPGe detectors;hence,precise modeling of the physical conditions of the detectors is highly desirable.In this study,the GEANT4 simulation framework with an optimized detector geometry adequately replicated the experimentally recorded spectrum.These detector simulations explored the idea of realizing a dead zone(an inactive volume)at the backend of an n-type coaxial Gecrystal.Using multigamma sources,the effect of true coincidence summing(TCS)on the full energy peak(FEP)efficiency calibration of an HPGe detector was investigated as a function of sample-to-detector distance.Good agreements between the simulated and experimental efficiencies as well as the simulated and analytically calculated summing coincidence correction coefficients were achieved.At a short distance between the source and detector,calculating the correction factors for a strong source posed challenges owing to significant deadtime and pile-up effects of the detection system.The described methodology can efficiently determine summing peak probabilities at short sample-to-detector distances.展开更多
To optimize secondary air nozzle structure in purifying burner,this study focused on the comparison of purification,combustion and NO_(x)emission characteristics of pulverized coal preheated by a 30 kW purifying burne...To optimize secondary air nozzle structure in purifying burner,this study focused on the comparison of purification,combustion and NO_(x)emission characteristics of pulverized coal preheated by a 30 kW purifying burner with coaxial and centrosymmetric structures.Centrosymmetric structure shifted the position of main burning region down in high-temperature reduction unit(HTRU),and the number of branches differently influenced the temperature in different regions with this structure.For reductive gas components,CO concentration with centrosymmetric structure was higher compared to coaxial structure,while the differences in H_(2)and CH_(4)concentrations were smaller.Centrosymmetric structure was more disadvantageous to improve physicochemical properties of pulverized coal compared to coaxial structure,and this structure with four branches further deteriorated its properties compared to two branches.In mild combustion unit(MCU),the temperature at top was lower with centrosymmetric structure,while was higher in the rest.Centrosymmetric structure more effectively reduced NO_(x)emission compared to coaxial structure,but with slight sacrifice of combustion efficiency(η).Moreover,both two-branch and four-branch centrosymmetric structures realized ultra-low NO_(x)emission(<50 mg·m^(-3))with high η of over 98.50%,and the former was more advantageous.With this optimal structure,η and NO_(x)emission were 99.25%and 40.42 mg·m^(-3).展开更多
Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different in...Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different injector geometries, while extensive tests on injection conditions were carried out for each injector geometry. The synchronous measurement of the pressure and heat release rate was applied, successfully capturing the process of the pressure and heat release rate enhanced coupling and developing into in-phase oscillation. By calculating Rayleigh index at the head and middle section of the chamber, it is shown that Rayleigh index of the middle section is even higher than that of the head, indicating a long heat release zone. When the combustion instability occurs, the pressure in propellant manifolds also oscillates with the same frequency and lags behind the oscillation in the combustor. Compared to the oscillation in the outer injector manifold, the oscillation in the inner injector manifold shows a higher correlation with that in the chamber in amplitude and phase. Based on numerical simulations of the multiphase cold flow inside the injector and combustion process in the chamber, it is found that injector geometries affect longitudinal combustion instability by changing spray cone angle. The spray with small cone angle is more sensitive to the modulation of longitudinal pressure wave in combustion simulations, which is more likely to excite the longitudinal combustion instability. Meanwhile, the combustion instability may be related to the pulsating coherent structure generated by the spray fluctuation, which is determined by injection conditions. Besides, a positive feedback closed-loop system associated with the active fluctuation and passive oscillation of the spray is believed to excite and sustain the longitudinal combustion instability.展开更多
Hexagonal boron nitride nanosheets(BNNSs)exhibit remarkable thermal and dielectric properties.However,their self-assembly and alignment in macroscopic forms remain challenging due to the chemical inertness of boron ni...Hexagonal boron nitride nanosheets(BNNSs)exhibit remarkable thermal and dielectric properties.However,their self-assembly and alignment in macroscopic forms remain challenging due to the chemical inertness of boron nitride,thereby limiting their performance in applications such as thermal management.In this study,we present a coaxial wet spinning approach for the fabrication of BNNSs/polymer composite fibers with high nanosheet orientation.The composite fibers were prepared using a superacid-based solvent system and showed a layered structure comprising an aramid core and an aramid/BNNSs sheath.Notably,the coaxial fibers exhibited significantly higher BNNSs alignment compared to uniaxial aramid/BNNSs fibers,primarily due to the additional compressive forces exerted at the core-sheath interface during the hot drawing process.With a BNNSs loading of 60 wt%,the resulting coaxial fibers showed exceptional properties,including an ultrahigh Herman orientation parameter of 0.81,thermal conductivity of 17.2 W m^(-1)K^(-1),and tensile strength of 192.5 MPa.These results surpassed those of uniaxial fibers and previously reported BNNSs composite fibers,making them highly suitable for applications such as wearable thermal management textiles.Our findings present a promising strategy for fabricating high-performance composite fibers based on BNNSs.展开更多
In nuclear reactors,temperature fluctuations of fluids may cause fatigue damage to adjacent structures;this is referred to as thermal striping.Research on thermal striping in the upper plenum has mainly focused on flu...In nuclear reactors,temperature fluctuations of fluids may cause fatigue damage to adjacent structures;this is referred to as thermal striping.Research on thermal striping in the upper plenum has mainly focused on fluid fields.Few experimental studies have been reported on solid structures in a fluid field with a coaxial jet.This study entailed an experimental study of the temperature fluctuations in the fluid and on a plate surface caused by a coaxial jet.The temperature fluctuations of the fluid and plate surfaces located at different heights were analyzed.The cause of the temperature fluctuation was analyzed using a transient temperature distribution.The results show that the mixing of the hot and cold fluids gradually becomes uniform in the positive axial direction.The average surface temperatures tended to be consistent.When the jet reaches the plate surface,the swing of the jet center,contraction and expansion of the cold jet,and changes in the jet shape result in temperature fluctuations.The intensity of the temperature fluctuation was affected by the position.More attention should be paid when the plate is located at a lower height,and between the hot and cold-fluid nozzles.展开更多
In this study,the effects of ultrasonic coaxial assisted TIG welding(U-TIG)on the formation,microstructure,and mechanical properties of TC4 titanium alloy welded joints were investigated.The results indicated that at ...In this study,the effects of ultrasonic coaxial assisted TIG welding(U-TIG)on the formation,microstructure,and mechanical properties of TC4 titanium alloy welded joints were investigated.The results indicated that at optimal ultrasonic power and welding current settings,remarkable improvements of welded joint were observed.Specifically,the weld depth-to-width ratio increased by 267%compared to conventional TIG welding,reaching 0.22.Furthermore,the microhardness of the welded seam increased by 53%,reaching 550.1 HV,while the tensile strength of the welded joint rose to 1197.7 MPa,representing a 12.2%enhancement.The compressing effect of ultrasound concentrates the energy of the arc,thereby improving the penetration depth of the welded seam.In addition,ultrasonic cavitation plays a crucial role in refining the grain structure of the weld seam,consequently enhancing its strength.展开更多
In space,surface tension plays an important role and liquid behaviour is much different from that on the ground.The static capillary surfaces in the annular space between two coaxial cones under microgravity are studi...In space,surface tension plays an important role and liquid behaviour is much different from that on the ground.The static capillary surfaces in the annular space between two coaxial cones under microgravity are studied in this paper.Theoretical expressions of the capillary surfaces are derived and a procedure is developed to predict the capillary surfaces based on the expressions.By considering various liquid contact angles,liquid volumes,and container geometries,numerical simulation with the volume of fluid method is carried out and microgravity experiments in Beijing Drop Tower are performed.The numerical and experimental results are in good agreement with theoretical predictions.Furthermore,capillary surfaces in an annulus with constant cross-section and in a spherical tank with a central column are also discussed.z3 will decrease obviously with the increase of the liquid contact angle.The theoretical models and findings will be great helpful for liquid management in space and the evaluation of propellant residue.展开更多
Unsubmerged cavitating abrasive waterjet(UCAWJ)has been shown to artificially create a submerged environment that produces shear cavitation,which effectively enhances rock-breaking performance.The shear cavitation gen...Unsubmerged cavitating abrasive waterjet(UCAWJ)has been shown to artificially create a submerged environment that produces shear cavitation,which effectively enhances rock-breaking performance.The shear cavitation generation and collapse intensity depend on the pressure difference between the intermediate high-speed abrasive waterjet and the coaxial low-speed waterjet.However,the effect of the pressure of the coaxial low-speed waterjet is pending.For this purpose,the effect of low-speed waterjet pressure on rock-breaking performance at different standoff distances was experimentally investigated,and the effects of erosion time and ruby nozzle diameter on erosion performance were discussed.Finally,the micromorphology of the sandstone was observed at different locations.The results show that increased erosion time and ruby nozzle diameter can significantly improve the rock-breaking performance.At different standoff distances,the mass loss increases first and then decreases with the increase of low-speed waterjet pressure,the maximum mass loss is 10.4 g at a low-speed waterjet pressure of0.09 MPa.The surface morphology of cavitation erosion was measured using a 3D profiler,the increase in both erosion depth and surface roughness indicated a significant increase in the intensity of the shear cavitation collapse.At a low-speed waterjet pressure of 0.18 MPa,the cavitation erosion surface depth can reach 600μm with a roughness of 127μm.展开更多
The rotator cuff tear has emerged as a significant global health concern.However,existing therapies fail to fully restore the intricate bone-to-tendon gradients,resulting in compromised biomechanical functionalities o...The rotator cuff tear has emerged as a significant global health concern.However,existing therapies fail to fully restore the intricate bone-to-tendon gradients,resulting in compromised biomechanical functionalities of the reconstructed enthesis tissues.Herein,a tri-layered core–shell microfibrous scaffold with layer-specific growth factors(GFs)release is developed using coaxial electrohydrodynamic(EHD)printing for in situ cell recruitment and differentiation to facilitate gradient enthesis tissue repair.Stromal cell-derived factor-1(SDF-1)is loaded in the shell,while basic fibroblast GF,transforming GF-beta,and bone morphogenetic protein-2 are loaded in the core of the EHD-printed microfibrous scaffolds in a layer-specific manner.Correspondingly,the tri-layered microfibrous scaffolds have a core–shell fiber size of(25.7±5.1)μm,with a pore size sequentially increasing from(81.5±4.6)μm to(173.3±6.9)μm,and to(388.9±6.9μm)for the tenogenic,chondrogenic,and osteogenic instructive layers.A rapid release of embedded GFs is observed within the first 2 d,followed by a faster release of SDF-1 and a slightly slower release of differentiation GFs for approximately four weeks.The coaxial EHD-printed microfibrous scaffolds significantly promote stem cell recruitment and direct their differentiation toward tenocyte,chondrocyte,and osteocyte phenotypes in vitro.When implanted in vivo,the tri-layered core–shell microfibrous scaffolds rapidly restored the biomechanical functions and promoted enthesis tissue regeneration with native-like bone-to-tendon gradients.Our findings suggest that the microfibrous scaffolds with layer-specific GFs release may offer a promising clinical solution for enthesis regeneration.展开更多
High-temperature thin-film sensors(TFSs)often suffer from inadequate tolerance to elevated temperatures.In this study,an innovative approach is presented to fabricate in situ integrated TFSs with a core-shell structur...High-temperature thin-film sensors(TFSs)often suffer from inadequate tolerance to elevated temperatures.In this study,an innovative approach is presented to fabricate in situ integrated TFSs with a core-shell structure on alloy components using coaxial multi-ink printing technique.This method replaces traditional layerby-layer(LbL) deposition and LbL sintering processes and achieves simplified one-step manufacturing.The coaxial TFS includes a conductive Pt core for conducting and sensing and a dielectric shell for electrical isolation and high-temperature protection.The coaxial Pt resistance grid demonstrates excellent high-temperature stability,with a resistance drift rate of only 0.08%·h^(-1) at 800 ℃,significantly lower than traditional Pt TFSs.By employing this method,a Pt thin-film strain gauge(TFSG) is fabricated that boasts remarkable high-temperature electromechanical properties.This effectively addresses the problem of sensitivity degradation experienced by traditional LbL Pt TFSGs when subjected to high temperatures.We demonstrate the system integration potential of the technique by printing and verifying the functionality of a long-path thinfilm resistance grid on turbine blades,which can withstand butane flame up to ~1300℃.These results showcase the potential of core-shell structure of the coaxial TFS for high-temperature applications,providing a novel approach to develop high-performance TFS beyond traditional multilayer structure.展开更多
As the elevator and rudder can be used actively for control,in addition to the rotors,Coaxial High-speed Helicopters(CHHs)have the problems of control redundancy and changing control authority in the transition mode.T...As the elevator and rudder can be used actively for control,in addition to the rotors,Coaxial High-speed Helicopters(CHHs)have the problems of control redundancy and changing control authority in the transition mode.This paper presents a robust-augmentation transitioning flight control design for a CHH under the adverse conditions of parametric uncertainties and external disturbances.First,based on control characteristic analysis,an Adaptive Filtered Nonlinear Dynamic Inversion(AFNDI)controller is proposed for the angular rate to handle the effect of unknown unstructured uncertainties and external turbulence.Theoretical analysis proves that the presented angular rate controller can guarantee steady-state and transient performance.Furthermore,the attitude angle and velocity controllers are also added.Then,an Incremental-based Nonlinear Prioritizing Control Allocation(INPCA)method is designed to take into account control surface transition and changing control authority,which efficiently distributes the required moments between coaxial rotors and aero-surfaces,and avoids the control reversal problem of the yaw channel.In the proposed control architecture,the low-pass filter is introduced to alleviate the adverse influence of time delay and measurement noise.Finally,the effectiveness of the proposed controller is demonstrated through nonlinear numerical simulations,and is compared with existing methods.Simulation results show that the proposed control law can improve both capabilities of disturbance rejection and fast response,and works satisfactorily for the CHH transitioning control characteristic.展开更多
High-resolution numerical simulations for wake vortical flows have long been a challenge in rotor aerodynamics.A novel spectrum-optimized sixth-order Weighted Essentially NonOscillatory(WENO)scheme is proposed to disc...High-resolution numerical simulations for wake vortical flows have long been a challenge in rotor aerodynamics.A novel spectrum-optimized sixth-order Weighted Essentially NonOscillatory(WENO)scheme is proposed to discretize inviscid fluxes on moving overset grids,and the Improved Delayed Detached Eddy Simulation(IDDES)is employed to resolve turbulent vortices.The integration of these methods facilitates a comprehensive numerical investigation into the unsteady vortical flows over coaxial rotors in hover.The results highlight the substantial improvement in numerical resolution,in terms of both spatial structure and temporal evolution of unsteady multiscale wake vortices.Coaxial rotors in hover manifest three primary scales of wake vortex structures:(A)the helical evolution of primary blade tip vortices and the periodic occurrence of strong Blade-Vortex Interactions(BVI);(B)the continuous shedding of small-scale horseshoeshaped vortices from the trailing edges of rotor blades,forming the vortex sheets;(C)the emergence of small-scale secondary vortex braids induced by interactions between rotor tip vortices and the vortex sheets.These vortex structures and their interactions cause high-frequency oscillations in rotor disk loads and induce unsteady perturbations in the local flow field.Interactions among these primary vortices,coupled with the generation of secondary vortices,result in the dissipation,distortion,and breakup of the rotor tip vortices,ultimately forming a vortex soup.Notably,a substantial quantity of seemingly weak small-scale secondary vortex braids significantly contribute to energy dissipation during the evolution of wake vortices for coaxial rotors in hover.ó2024 Chinese Society of Aeronautics and Astronautics.Production and hosting by Elsevier Ltd.This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).展开更多
Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In...Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.展开更多
In this study,numerical simulations of the pinching-off phenomena displayed by the dispersed phase in a continuous phase have been conducted using COMSOL Multiphysics(level-set method).Four flow patterns,namely“drop ...In this study,numerical simulations of the pinching-off phenomena displayed by the dispersed phase in a continuous phase have been conducted using COMSOL Multiphysics(level-set method).Four flow patterns,namely“drop flow”,“jet flow”,“squeeze flow”,and“co-flow”,have been obtained for different flow velocity ratios,channel diameter ratios,density ratios,viscosity ratios,and surface tension.The flow pattern map of two-phase flow in coaxial microchannels has been obtained accordingly,and the associated droplet generation process has been critically discussed considering the related frequency,diameter,and pinch-off length.In particular,it is shown that the larger the flow velocity ratio,the smaller the diameter of generated droplets and the shorter the pinch-off length.The pinch-off length of a droplet is influenced by the channel diameter ratio and density ratio.The changes in viscosity ratio have a negligible influence on the droplet generation pinching frequency.With an increase in surface tension,the frequency of generation and pinch-off length of droplets decrease,but for small surface tension the generation diameter of droplet increases.展开更多
BACKGROUND The overlap of imaging manifestations among distinct splenic lesions gives rise to a diagnostic dilemma.Consequently,a definitive diagnosis primarily relies on his-tological results.The ultrasound(US)-guide...BACKGROUND The overlap of imaging manifestations among distinct splenic lesions gives rise to a diagnostic dilemma.Consequently,a definitive diagnosis primarily relies on his-tological results.The ultrasound(US)-guided coaxial core needle biopsy(CNB)not only procures sufficient tissue to help clarify the diagnosis,but reduces the incidence of puncture-related complications.CASE SUMMARY A 41-year-old female,with a history of pulmonary tuberculosis,was admitted to our hospital with multiple indeterminate splenic lesions.Gray-scale ultrasono-graphy demonstrated splenomegaly with numerous well-defined hypoechoic ma-sses.Abdominal contrast-enhanced computed tomography(CT)showed an en-larged spleen with multiple irregular-shaped,peripherally enhancing,hypodense lesions.Positron emission CT revealed numerous abnormal hyperglycemia foci.These imaging findings strongly indicated the possibility of infectious disease as the primary concern,with neoplastic lesions requiring exclusion.To obtain the precise pathological diagnosis,the US-guided coaxial CNB of the spleen was ca-rried out.The patient did not express any discomfort during the procedure.CONCLUSION Percutaneous US-guided coaxial CNB is an excellent and safe option for obtaining precise splenic tissue samples,as it significantly enhances sample yield for exact pathological analysis with minimum trauma to the spleen parenchyma and sur-rounding tissue.展开更多
基金supported by the National Natural Science Foundation of China(No.51975293)Aeronautical Science Foundation of China (No. 2019ZD052010)
文摘Aiming at the shortcomings of traditional contact measurement methods such as low measurement efficiency,high cost and low accuracy,a non-contact optical measurement method based on the laser displacement sensor is proposed.According to the relevant regulations of the coaxiality error evaluation standard and the structural characteristics of the compound gear shaft,we have designed and built a set of supporting software system as well as a hardware test platform.In this paper,the distance difference threshold and scale threshold methods are used to eliminate outlier data.The least squares circle is selected to calculate the center of the circle and the minimum containment cylinder axis method is used as the reference axis of the composite gear shaft.Compensated by the standard step shaft calibration,the coaxiality error of the composite gear shaft can be measured to be within 0.01 mm in less than two minutes.The range value of the multi-section measurement test is 0.065 mm.The average coaxiality error is∅0.476 mm.
基金Supported by the National Natural Science Foundation of China(U23A20487)the National Key R&D Program of China(2022YFB3206000)+1 种基金Dr.Li Dak Sum&Yip Yio Chin Development Fund for Regenerative Medicine,Zhejiang Universitythe National Natural Science Foundation of China(61975172).
文摘Fluorescence imaging in the second near-infrared window(NIR-II,900-1880 nm)offers high signalto-background ratio(SBR),enhanced definition,and superior tissue penetration,making it ideal for real-time surgical navigation.However,with single-channel imaging,surgeons must frequently switch between the surgi⁃cal field and the NIR-II images on the monitor.To address this,a coaxial dual-channel imaging system that com⁃bines visible light and 1100 nm longpass(1100LP)fluorescence was developed.The system features a custom⁃ized coaxial dual-channel lens with optimized distortion,achieving precise alignment with an error of less than±0.15 mm.Additionally,the shared focusing mechanism simplifies operation.Using FDA-approved indocya⁃nine green(ICG),the system was successfully applied in dual-channel guided rat lymph node excision,and blood supply assessment of reconstructed human flap.This approach enhances surgical precision,improves opera⁃tional efficiency,and provides a valuable reference for further clinical translation of NIR-II fluorescence imaging.
基金funded by the National Natural Science Foundation of China(No.52105060)the Special Transmission Project,China(No.KY-1044-2023-0458)。
文摘To reduce the vibration of the Coaxial Helicopter Main Transmission System(CHMTS)considering both level and vertical flight conditions,a vibration evaluation and optimization model for the CHMTS was built.The vibration simulation model of the CHMTS was set up by gear dynamics theory and loaded contact analysis.For better evaluation of the system vibration,a vibration evaluation method for the CHMTS was established by the G1 method-variation coefficient method.A hybrid Gravitational Search Algorithm-Simulated Annealing(GSA-SA)algorithm was combined to balance convergence speed and searching accuracy.The principle test was conducted to prove the accuracy of theoretical method,in which the maximum relative error is16.26%.The optional results show that the vibration of the optimized transmission system decreases significantly,in which the maximum reduction of key vibration indicators reaches more than 20%.The theoretical results have been compared to the experiment to verify the effectiveness of the vibration optimization method.The proposed method could be extended to other fields.
基金funded by the National Key R&D Program of China,Grant No.2024YFF0504904.
文摘The packaging quality of coaxial laser diodes(CLDs)plays a pivotal role in determining their optical performance and long-term reliability.As the core packaging process,high-precision laser welding requires precise control of process parameters to suppress optical power loss.However,the complex nonlinear relationship between welding parameters and optical power loss renders traditional trial-and-error methods inefficient and imprecise.To address this challenge,a physics-informed(PI)and data-driven collaboration approach for welding parameter optimization is proposed.First,thermal-fluid-solid coupling finite element method(FEM)was employed to quantify the sensitivity of welding parameters to physical characteristics,including residual stress.This analysis facilitated the identification of critical factors contributing to optical power loss.Subsequently,a Gaussian process regression(GPR)model incorporating finite element simulation prior knowledge was constructed based on the selected features.By introducing physics-informed kernel(PIK)functions,stress distribution patterns were embedded into the prediction model,achieving high-precision optical power loss prediction.Finally,a Bayesian optimization(BO)algorithm with an adaptive sampling strategy was implemented for efficient parameter space exploration.Experimental results demonstrate that the proposedmethod effectively establishes explicit physical correlations between welding parameters and optical power loss.The optimized welding parameters reduced optical power loss by 34.1%,providing theoretical guidance and technical support for reliable CLD packaging.
基金supported by the Natural Science Foundation of Gansu Province(No.22JR5RA118)the National Natural Science Foundation of China(Nos.12121005 and U1932138)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB34010000)。
文摘The measurement of low-level radioactivity using high-purity germanium(HPGe)detectors is important in applications such as environmental background radiation,material screening,and rare decays.The dead layers,dead zones,aluminum shell thickness,and diameter of Ge crystals are the most influential factors affecting the performance of HPGe detectors;hence,precise modeling of the physical conditions of the detectors is highly desirable.In this study,the GEANT4 simulation framework with an optimized detector geometry adequately replicated the experimentally recorded spectrum.These detector simulations explored the idea of realizing a dead zone(an inactive volume)at the backend of an n-type coaxial Gecrystal.Using multigamma sources,the effect of true coincidence summing(TCS)on the full energy peak(FEP)efficiency calibration of an HPGe detector was investigated as a function of sample-to-detector distance.Good agreements between the simulated and experimental efficiencies as well as the simulated and analytically calculated summing coincidence correction coefficients were achieved.At a short distance between the source and detector,calculating the correction factors for a strong source posed challenges owing to significant deadtime and pile-up effects of the detection system.The described methodology can efficiently determine summing peak probabilities at short sample-to-detector distances.
基金Postdoctoral Fellowship Program of CPSF(GZC20232672)CAS Project for Young Scientists in Basic Research(YSBR-028)the Strategic Priority Research Program(XDA29010200)are gratefully acknowledged.
文摘To optimize secondary air nozzle structure in purifying burner,this study focused on the comparison of purification,combustion and NO_(x)emission characteristics of pulverized coal preheated by a 30 kW purifying burner with coaxial and centrosymmetric structures.Centrosymmetric structure shifted the position of main burning region down in high-temperature reduction unit(HTRU),and the number of branches differently influenced the temperature in different regions with this structure.For reductive gas components,CO concentration with centrosymmetric structure was higher compared to coaxial structure,while the differences in H_(2)and CH_(4)concentrations were smaller.Centrosymmetric structure was more disadvantageous to improve physicochemical properties of pulverized coal compared to coaxial structure,and this structure with four branches further deteriorated its properties compared to two branches.In mild combustion unit(MCU),the temperature at top was lower with centrosymmetric structure,while was higher in the rest.Centrosymmetric structure more effectively reduced NO_(x)emission compared to coaxial structure,but with slight sacrifice of combustion efficiency(η).Moreover,both two-branch and four-branch centrosymmetric structures realized ultra-low NO_(x)emission(<50 mg·m^(-3))with high η of over 98.50%,and the former was more advantageous.With this optimal structure,η and NO_(x)emission were 99.25%and 40.42 mg·m^(-3).
基金support from the National Natural Science Foundation of China(No.12002386).
文摘Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different injector geometries, while extensive tests on injection conditions were carried out for each injector geometry. The synchronous measurement of the pressure and heat release rate was applied, successfully capturing the process of the pressure and heat release rate enhanced coupling and developing into in-phase oscillation. By calculating Rayleigh index at the head and middle section of the chamber, it is shown that Rayleigh index of the middle section is even higher than that of the head, indicating a long heat release zone. When the combustion instability occurs, the pressure in propellant manifolds also oscillates with the same frequency and lags behind the oscillation in the combustor. Compared to the oscillation in the outer injector manifold, the oscillation in the inner injector manifold shows a higher correlation with that in the chamber in amplitude and phase. Based on numerical simulations of the multiphase cold flow inside the injector and combustion process in the chamber, it is found that injector geometries affect longitudinal combustion instability by changing spray cone angle. The spray with small cone angle is more sensitive to the modulation of longitudinal pressure wave in combustion simulations, which is more likely to excite the longitudinal combustion instability. Meanwhile, the combustion instability may be related to the pulsating coherent structure generated by the spray fluctuation, which is determined by injection conditions. Besides, a positive feedback closed-loop system associated with the active fluctuation and passive oscillation of the spray is believed to excite and sustain the longitudinal combustion instability.
基金This work was supported by the National Key Research and Development Project(Nos.2019YFA0705403,2022YFA1205300)the National Natural Science Foundation of China(No.T2293693)+3 种基金the Guangdong Innovative and Entrepreneurial Research Team Program(No.2017ZT07C341)the Guangdong Basic and Applied Basic Research Foundation(No.2020B0301030002)the Shenzhen Basic Research Project(Nos.WDZC20200824091903001,JSGG20220831105402004)Zhiyuan Xiong thanks the financial support from South China University of Technology.
文摘Hexagonal boron nitride nanosheets(BNNSs)exhibit remarkable thermal and dielectric properties.However,their self-assembly and alignment in macroscopic forms remain challenging due to the chemical inertness of boron nitride,thereby limiting their performance in applications such as thermal management.In this study,we present a coaxial wet spinning approach for the fabrication of BNNSs/polymer composite fibers with high nanosheet orientation.The composite fibers were prepared using a superacid-based solvent system and showed a layered structure comprising an aramid core and an aramid/BNNSs sheath.Notably,the coaxial fibers exhibited significantly higher BNNSs alignment compared to uniaxial aramid/BNNSs fibers,primarily due to the additional compressive forces exerted at the core-sheath interface during the hot drawing process.With a BNNSs loading of 60 wt%,the resulting coaxial fibers showed exceptional properties,including an ultrahigh Herman orientation parameter of 0.81,thermal conductivity of 17.2 W m^(-1)K^(-1),and tensile strength of 192.5 MPa.These results surpassed those of uniaxial fibers and previously reported BNNSs composite fibers,making them highly suitable for applications such as wearable thermal management textiles.Our findings present a promising strategy for fabricating high-performance composite fibers based on BNNSs.
基金supported by the National Natural Science Foundation of China (No. 52075173)the Overseas Expertise Introduction Project for Discipline Innovation (No. B13020)
文摘In nuclear reactors,temperature fluctuations of fluids may cause fatigue damage to adjacent structures;this is referred to as thermal striping.Research on thermal striping in the upper plenum has mainly focused on fluid fields.Few experimental studies have been reported on solid structures in a fluid field with a coaxial jet.This study entailed an experimental study of the temperature fluctuations in the fluid and on a plate surface caused by a coaxial jet.The temperature fluctuations of the fluid and plate surfaces located at different heights were analyzed.The cause of the temperature fluctuation was analyzed using a transient temperature distribution.The results show that the mixing of the hot and cold fluids gradually becomes uniform in the positive axial direction.The average surface temperatures tended to be consistent.When the jet reaches the plate surface,the swing of the jet center,contraction and expansion of the cold jet,and changes in the jet shape result in temperature fluctuations.The intensity of the temperature fluctuation was affected by the position.More attention should be paid when the plate is located at a lower height,and between the hot and cold-fluid nozzles.
基金supported by the National Natural Science Foundation of China(No.52305362)the State Key Lab of Advanced Welding and Joining,Harbin Institute of Technology(No.AWJ-20M06).
文摘In this study,the effects of ultrasonic coaxial assisted TIG welding(U-TIG)on the formation,microstructure,and mechanical properties of TC4 titanium alloy welded joints were investigated.The results indicated that at optimal ultrasonic power and welding current settings,remarkable improvements of welded joint were observed.Specifically,the weld depth-to-width ratio increased by 267%compared to conventional TIG welding,reaching 0.22.Furthermore,the microhardness of the welded seam increased by 53%,reaching 550.1 HV,while the tensile strength of the welded joint rose to 1197.7 MPa,representing a 12.2%enhancement.The compressing effect of ultrasound concentrates the energy of the arc,thereby improving the penetration depth of the welded seam.In addition,ultrasonic cavitation plays a crucial role in refining the grain structure of the weld seam,consequently enhancing its strength.
基金supported by the China Manned Space Engineering Program(Fluid Physics Experimental Rack and the Priority Research Program of Space Station)the Natural Science Foundation Project(Grant No.12032020).
文摘In space,surface tension plays an important role and liquid behaviour is much different from that on the ground.The static capillary surfaces in the annular space between two coaxial cones under microgravity are studied in this paper.Theoretical expressions of the capillary surfaces are derived and a procedure is developed to predict the capillary surfaces based on the expressions.By considering various liquid contact angles,liquid volumes,and container geometries,numerical simulation with the volume of fluid method is carried out and microgravity experiments in Beijing Drop Tower are performed.The numerical and experimental results are in good agreement with theoretical predictions.Furthermore,capillary surfaces in an annulus with constant cross-section and in a spherical tank with a central column are also discussed.z3 will decrease obviously with the increase of the liquid contact angle.The theoretical models and findings will be great helpful for liquid management in space and the evaluation of propellant residue.
基金financially supported by the National Natural Science Foundation of China (Nos.52175245 and 52274093)the Natural Science Foundation of Hubei Province (No.2021CFB462)the Knowledge Innovation Special Project of Wuhan (whkxjsj007)。
文摘Unsubmerged cavitating abrasive waterjet(UCAWJ)has been shown to artificially create a submerged environment that produces shear cavitation,which effectively enhances rock-breaking performance.The shear cavitation generation and collapse intensity depend on the pressure difference between the intermediate high-speed abrasive waterjet and the coaxial low-speed waterjet.However,the effect of the pressure of the coaxial low-speed waterjet is pending.For this purpose,the effect of low-speed waterjet pressure on rock-breaking performance at different standoff distances was experimentally investigated,and the effects of erosion time and ruby nozzle diameter on erosion performance were discussed.Finally,the micromorphology of the sandstone was observed at different locations.The results show that increased erosion time and ruby nozzle diameter can significantly improve the rock-breaking performance.At different standoff distances,the mass loss increases first and then decreases with the increase of low-speed waterjet pressure,the maximum mass loss is 10.4 g at a low-speed waterjet pressure of0.09 MPa.The surface morphology of cavitation erosion was measured using a 3D profiler,the increase in both erosion depth and surface roughness indicated a significant increase in the intensity of the shear cavitation collapse.At a low-speed waterjet pressure of 0.18 MPa,the cavitation erosion surface depth can reach 600μm with a roughness of 127μm.
基金financially supported by the National Key Research and Development Program of China(2018YFA0703003)National Natural Science Foundation of China(82072429,52125501,82371590)+6 种基金the Program for Innovation Team of Shaanxi Province(2023-CX-TD-17)the Key Research&Development Program of Shaanxi Province(2024SF-YBXM-355,2020SF-093,2021LLRH-08)the Natural Science Foundation of Henan Province(222300420358)the Postdoctoral Project of Shaanxi Province(2023BSHYDZZ30)the Postdoctoral Fellowship Program of CPSF(GZB20230573)the Institutional Foundation of the First Affiliated Hospital of Xi’an Jiaotong University(2019ZYTS-02)the Fundamental Research Funds for the Central Universities.
文摘The rotator cuff tear has emerged as a significant global health concern.However,existing therapies fail to fully restore the intricate bone-to-tendon gradients,resulting in compromised biomechanical functionalities of the reconstructed enthesis tissues.Herein,a tri-layered core–shell microfibrous scaffold with layer-specific growth factors(GFs)release is developed using coaxial electrohydrodynamic(EHD)printing for in situ cell recruitment and differentiation to facilitate gradient enthesis tissue repair.Stromal cell-derived factor-1(SDF-1)is loaded in the shell,while basic fibroblast GF,transforming GF-beta,and bone morphogenetic protein-2 are loaded in the core of the EHD-printed microfibrous scaffolds in a layer-specific manner.Correspondingly,the tri-layered microfibrous scaffolds have a core–shell fiber size of(25.7±5.1)μm,with a pore size sequentially increasing from(81.5±4.6)μm to(173.3±6.9)μm,and to(388.9±6.9μm)for the tenogenic,chondrogenic,and osteogenic instructive layers.A rapid release of embedded GFs is observed within the first 2 d,followed by a faster release of SDF-1 and a slightly slower release of differentiation GFs for approximately four weeks.The coaxial EHD-printed microfibrous scaffolds significantly promote stem cell recruitment and direct their differentiation toward tenocyte,chondrocyte,and osteocyte phenotypes in vitro.When implanted in vivo,the tri-layered core–shell microfibrous scaffolds rapidly restored the biomechanical functions and promoted enthesis tissue regeneration with native-like bone-to-tendon gradients.Our findings suggest that the microfibrous scaffolds with layer-specific GFs release may offer a promising clinical solution for enthesis regeneration.
基金financially supported by Shenyang Engine Design and Research Institute (No.JC 3 602007026)。
文摘High-temperature thin-film sensors(TFSs)often suffer from inadequate tolerance to elevated temperatures.In this study,an innovative approach is presented to fabricate in situ integrated TFSs with a core-shell structure on alloy components using coaxial multi-ink printing technique.This method replaces traditional layerby-layer(LbL) deposition and LbL sintering processes and achieves simplified one-step manufacturing.The coaxial TFS includes a conductive Pt core for conducting and sensing and a dielectric shell for electrical isolation and high-temperature protection.The coaxial Pt resistance grid demonstrates excellent high-temperature stability,with a resistance drift rate of only 0.08%·h^(-1) at 800 ℃,significantly lower than traditional Pt TFSs.By employing this method,a Pt thin-film strain gauge(TFSG) is fabricated that boasts remarkable high-temperature electromechanical properties.This effectively addresses the problem of sensitivity degradation experienced by traditional LbL Pt TFSGs when subjected to high temperatures.We demonstrate the system integration potential of the technique by printing and verifying the functionality of a long-path thinfilm resistance grid on turbine blades,which can withstand butane flame up to ~1300℃.These results showcase the potential of core-shell structure of the coaxial TFS for high-temperature applications,providing a novel approach to develop high-performance TFS beyond traditional multilayer structure.
文摘As the elevator and rudder can be used actively for control,in addition to the rotors,Coaxial High-speed Helicopters(CHHs)have the problems of control redundancy and changing control authority in the transition mode.This paper presents a robust-augmentation transitioning flight control design for a CHH under the adverse conditions of parametric uncertainties and external disturbances.First,based on control characteristic analysis,an Adaptive Filtered Nonlinear Dynamic Inversion(AFNDI)controller is proposed for the angular rate to handle the effect of unknown unstructured uncertainties and external turbulence.Theoretical analysis proves that the presented angular rate controller can guarantee steady-state and transient performance.Furthermore,the attitude angle and velocity controllers are also added.Then,an Incremental-based Nonlinear Prioritizing Control Allocation(INPCA)method is designed to take into account control surface transition and changing control authority,which efficiently distributes the required moments between coaxial rotors and aero-surfaces,and avoids the control reversal problem of the yaw channel.In the proposed control architecture,the low-pass filter is introduced to alleviate the adverse influence of time delay and measurement noise.Finally,the effectiveness of the proposed controller is demonstrated through nonlinear numerical simulations,and is compared with existing methods.Simulation results show that the proposed control law can improve both capabilities of disturbance rejection and fast response,and works satisfactorily for the CHH transitioning control characteristic.
文摘High-resolution numerical simulations for wake vortical flows have long been a challenge in rotor aerodynamics.A novel spectrum-optimized sixth-order Weighted Essentially NonOscillatory(WENO)scheme is proposed to discretize inviscid fluxes on moving overset grids,and the Improved Delayed Detached Eddy Simulation(IDDES)is employed to resolve turbulent vortices.The integration of these methods facilitates a comprehensive numerical investigation into the unsteady vortical flows over coaxial rotors in hover.The results highlight the substantial improvement in numerical resolution,in terms of both spatial structure and temporal evolution of unsteady multiscale wake vortices.Coaxial rotors in hover manifest three primary scales of wake vortex structures:(A)the helical evolution of primary blade tip vortices and the periodic occurrence of strong Blade-Vortex Interactions(BVI);(B)the continuous shedding of small-scale horseshoeshaped vortices from the trailing edges of rotor blades,forming the vortex sheets;(C)the emergence of small-scale secondary vortex braids induced by interactions between rotor tip vortices and the vortex sheets.These vortex structures and their interactions cause high-frequency oscillations in rotor disk loads and induce unsteady perturbations in the local flow field.Interactions among these primary vortices,coupled with the generation of secondary vortices,result in the dissipation,distortion,and breakup of the rotor tip vortices,ultimately forming a vortex soup.Notably,a substantial quantity of seemingly weak small-scale secondary vortex braids significantly contribute to energy dissipation during the evolution of wake vortices for coaxial rotors in hover.ó2024 Chinese Society of Aeronautics and Astronautics.Production and hosting by Elsevier Ltd.This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).
基金supported by Bhabha Atomic Research Centre, Department of Atomic Energy, Government of IndiaDepartment of Atomic Energy, Government of India for financial assistance under DAE Doctoral Fellowship Scheme-2018。
文摘Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon plasma.The triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.
基金funded by University Natural Science Research Project of Anhui Province,Grant Numbers (KJ2020A0826,2022AH051885,2022AH051891,2022AH030160,62303231)Intelligent Detection Research Team Funds for the Anhui Institute of Information Technology,Grant Number (AXG2023_kjc_5004).
文摘In this study,numerical simulations of the pinching-off phenomena displayed by the dispersed phase in a continuous phase have been conducted using COMSOL Multiphysics(level-set method).Four flow patterns,namely“drop flow”,“jet flow”,“squeeze flow”,and“co-flow”,have been obtained for different flow velocity ratios,channel diameter ratios,density ratios,viscosity ratios,and surface tension.The flow pattern map of two-phase flow in coaxial microchannels has been obtained accordingly,and the associated droplet generation process has been critically discussed considering the related frequency,diameter,and pinch-off length.In particular,it is shown that the larger the flow velocity ratio,the smaller the diameter of generated droplets and the shorter the pinch-off length.The pinch-off length of a droplet is influenced by the channel diameter ratio and density ratio.The changes in viscosity ratio have a negligible influence on the droplet generation pinching frequency.With an increase in surface tension,the frequency of generation and pinch-off length of droplets decrease,but for small surface tension the generation diameter of droplet increases.
文摘BACKGROUND The overlap of imaging manifestations among distinct splenic lesions gives rise to a diagnostic dilemma.Consequently,a definitive diagnosis primarily relies on his-tological results.The ultrasound(US)-guided coaxial core needle biopsy(CNB)not only procures sufficient tissue to help clarify the diagnosis,but reduces the incidence of puncture-related complications.CASE SUMMARY A 41-year-old female,with a history of pulmonary tuberculosis,was admitted to our hospital with multiple indeterminate splenic lesions.Gray-scale ultrasono-graphy demonstrated splenomegaly with numerous well-defined hypoechoic ma-sses.Abdominal contrast-enhanced computed tomography(CT)showed an en-larged spleen with multiple irregular-shaped,peripherally enhancing,hypodense lesions.Positron emission CT revealed numerous abnormal hyperglycemia foci.These imaging findings strongly indicated the possibility of infectious disease as the primary concern,with neoplastic lesions requiring exclusion.To obtain the precise pathological diagnosis,the US-guided coaxial CNB of the spleen was ca-rried out.The patient did not express any discomfort during the procedure.CONCLUSION Percutaneous US-guided coaxial CNB is an excellent and safe option for obtaining precise splenic tissue samples,as it significantly enhances sample yield for exact pathological analysis with minimum trauma to the spleen parenchyma and sur-rounding tissue.
