目的分析2型糖尿病患者使用门冬胰岛素30注射液(商品名:诺和锐30)与精蛋白锌重组赖脯胰岛素混合注射液(25R)(商品名:优泌乐25)治疗对空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平的调节作用。方法80例新诊断2型糖尿病...目的分析2型糖尿病患者使用门冬胰岛素30注射液(商品名:诺和锐30)与精蛋白锌重组赖脯胰岛素混合注射液(25R)(商品名:优泌乐25)治疗对空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平的调节作用。方法80例新诊断2型糖尿病的患者,随机分为优泌乐25组和诺和锐30组,每组40例。优泌乐25组患者使用优泌乐25治疗,诺和锐30组患者使用诺和锐30治疗。比较两组患者治疗前后血糖(FPG、2 h PG及HbA1c)水平及低血糖发生情况。结果治疗后,两组患者的FPG、2 h PG及HbA1c水平均较治疗前下降,差异有统计学意义(P<0.05);诺和锐30组患者的FPG(8.13±1.12)mmol/L高于优泌乐25组的(7.13±1.18)mmol/L,2 h PG(6.76±1.14)mmol/L及HbA1c(6.16±0.24)%均明显低于优泌乐25组的(9.88±1.82)mmol/L、(7.08±0.81)%,差异有统计学意义(P<0.05)。诺和锐30组患者的低血糖发生率2.50%低于优泌乐25组的5.00%,但对比差异无统计学意义(P>0.05)。结论诺和锐30与优泌乐25治疗2型糖尿病患者均可取得较佳的血糖控制效果,且不易发生低血糖等不良事件发生,但诺和锐30可更佳的控制餐后血糖,优泌乐25可更佳的控制空腹血糖。展开更多
提出了1种基于0.18μm CMOS工艺的低压低功耗、宽锁定范围、低复杂度的2分频直接注入锁定分频器.该分频器采用Class-C的LC-tank架构来降低电源电压,同时改善LC振荡器的起振情况.此外还采用双端注入混频技术来扩大锁定范围.仿真结果表明...提出了1种基于0.18μm CMOS工艺的低压低功耗、宽锁定范围、低复杂度的2分频直接注入锁定分频器.该分频器采用Class-C的LC-tank架构来降低电源电压,同时改善LC振荡器的起振情况.此外还采用双端注入混频技术来扩大锁定范围.仿真结果表明该分频器有很好的混频性能,且分频器核心电路(不包括输出buffer)在800 m V电源电压下的功耗仅为0.91 m W.在注入信号的功率为0 d Bm时,该分频器在没有任何调谐单元时的锁定范围为6.4-8.5 GHz.展开更多
Computational fuid dynamics(CFD)simulations of a single staged injection of H_(2) through a central wedge shaped strut and a multi staged injection through wall injectors are carried out by using Ansys CFX-12 code.Uns...Computational fuid dynamics(CFD)simulations of a single staged injection of H_(2) through a central wedge shaped strut and a multi staged injection through wall injectors are carried out by using Ansys CFX-12 code.Unstructured terahedral grids for narow channel and quarter geometries of the combustor are generated by using ICEM CFD.Steady three dimensional(3D)Reynods averaged Navier-stokes(RANS)simulations are carried out in the case of no H_(2) injection and compared with the simulations of single staged pilot and/or main H2 injections and multistage injection.Shear stuess transport(SST)based on k-ω turbulent model is adopted.Flow field visualization(omplex shock waves interactions)and static pressure distribution along the wall of the combustor are pradicted and compared with the experimental schlieren images and measured wall static pressures for validation.A good agreement is found between the CFD predicted results and the measured data.The narow and quarter geometries of the combustor give similar results with very small differences.Multi-staged injections of H_(2) enhance the turbulent H_(2)/air mixing by fomming vortices and additional shock waves(bow shocks).展开更多
文摘目的分析2型糖尿病患者使用门冬胰岛素30注射液(商品名:诺和锐30)与精蛋白锌重组赖脯胰岛素混合注射液(25R)(商品名:优泌乐25)治疗对空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平的调节作用。方法80例新诊断2型糖尿病的患者,随机分为优泌乐25组和诺和锐30组,每组40例。优泌乐25组患者使用优泌乐25治疗,诺和锐30组患者使用诺和锐30治疗。比较两组患者治疗前后血糖(FPG、2 h PG及HbA1c)水平及低血糖发生情况。结果治疗后,两组患者的FPG、2 h PG及HbA1c水平均较治疗前下降,差异有统计学意义(P<0.05);诺和锐30组患者的FPG(8.13±1.12)mmol/L高于优泌乐25组的(7.13±1.18)mmol/L,2 h PG(6.76±1.14)mmol/L及HbA1c(6.16±0.24)%均明显低于优泌乐25组的(9.88±1.82)mmol/L、(7.08±0.81)%,差异有统计学意义(P<0.05)。诺和锐30组患者的低血糖发生率2.50%低于优泌乐25组的5.00%,但对比差异无统计学意义(P>0.05)。结论诺和锐30与优泌乐25治疗2型糖尿病患者均可取得较佳的血糖控制效果,且不易发生低血糖等不良事件发生,但诺和锐30可更佳的控制餐后血糖,优泌乐25可更佳的控制空腹血糖。
文摘提出了1种基于0.18μm CMOS工艺的低压低功耗、宽锁定范围、低复杂度的2分频直接注入锁定分频器.该分频器采用Class-C的LC-tank架构来降低电源电压,同时改善LC振荡器的起振情况.此外还采用双端注入混频技术来扩大锁定范围.仿真结果表明该分频器有很好的混频性能,且分频器核心电路(不包括输出buffer)在800 m V电源电压下的功耗仅为0.91 m W.在注入信号的功率为0 d Bm时,该分频器在没有任何调谐单元时的锁定范围为6.4-8.5 GHz.
基金The authors would like to thank the German research foundation(DFG)for their financial support for this work in the framework of the research training group GRK 1095.
文摘Computational fuid dynamics(CFD)simulations of a single staged injection of H_(2) through a central wedge shaped strut and a multi staged injection through wall injectors are carried out by using Ansys CFX-12 code.Unstructured terahedral grids for narow channel and quarter geometries of the combustor are generated by using ICEM CFD.Steady three dimensional(3D)Reynods averaged Navier-stokes(RANS)simulations are carried out in the case of no H_(2) injection and compared with the simulations of single staged pilot and/or main H2 injections and multistage injection.Shear stuess transport(SST)based on k-ω turbulent model is adopted.Flow field visualization(omplex shock waves interactions)and static pressure distribution along the wall of the combustor are pradicted and compared with the experimental schlieren images and measured wall static pressures for validation.A good agreement is found between the CFD predicted results and the measured data.The narow and quarter geometries of the combustor give similar results with very small differences.Multi-staged injections of H_(2) enhance the turbulent H_(2)/air mixing by fomming vortices and additional shock waves(bow shocks).
