期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Impact of the Liaison Committee of Food and Nutrition on the Quality of Patients' Meals 被引量:1
1
作者 Yahia Abouda Nabiha Bouafia +4 位作者 Mohamed Mahjoub Wadiaa Bannour Riadh Essokri Hanen Zendah Mansour N jab 《Journal of Life Sciences》 2012年第8期864-870,共7页
At hospital, nutrition represents an important value of care, particularly for patients at risk. However, it is observed that for various reasons, the restoration of the hospitalized patients is often neglected in the... At hospital, nutrition represents an important value of care, particularly for patients at risk. However, it is observed that for various reasons, the restoration of the hospitalized patients is often neglected in the privileges of the medical care. The establishment of a Liaison Committee of Food and Nutrition (LCFN) within a health establishment has shown according to several works, its positive impact in improving the hygienic quality and nutritional dishes served to patients. In this framework, we conducted a quasi-experimental study into CHU F hached Sousse of Tunisia type (before/after, creation LCFN) in order to assess the role of such structure (LCFN) in the qualification and the improvement of patients' food. Our study was based during the two phases (2007/2010) on the same methodology. Thus we have conducted an audit of observation of hygiene practices along the distribution chain of patient's meals and the samples for microbiological analyzes from food, surfaces, equipment and personnel's hands.The results obtained have shown, in one hand, a degradation of the average rate of contamination for the bacteriological analyzes, and in the other hand, an evolution of the rate of hygiene standards respected. According to this study, the role played by the LCFN is becoming more and clearer in the improvement of the hygienic quality of patients' dishes without forgetting the impact of improving the nutritional quality and Hedonics. 展开更多
关键词 HYGIENE FOOD PATIENT clfn.
在线阅读 下载PDF
人集成干扰素α的构建及其抗病毒活性验证
2
作者 邹万成 陈竞 +3 位作者 李沛恒 李乐天 蔡锦顺 金宁一 《中国生物制品学杂志》 CAS CSCD 2024年第6期739-744,750,共7页
目的构建1条新的人集成干扰素α(consensus interferonα,cIFNα)序列,并验证其抗病毒效果。方法综合57条人源IFNα序列,经软件比对分析选出各个位点保守氨基酸偏好性,人工合成新的cIFN序列hIC至pUC-57载体中,与pCK连接,构建真核表达载... 目的构建1条新的人集成干扰素α(consensus interferonα,cIFNα)序列,并验证其抗病毒效果。方法综合57条人源IFNα序列,经软件比对分析选出各个位点保守氨基酸偏好性,人工合成新的cIFN序列hIC至pUC-57载体中,与pCK连接,构建真核表达载体pCK-hIC,转染293T细胞表达目的蛋白hIC;于增强型绿色荧光蛋白水疱性口炎病毒(enhanced green fluorescent protein vesicular stomatitis virus,VSV-EGFP)感染A549细胞前后用其孵育细胞,经荧光观察、结晶紫染色和流式细胞术体外分析hIC对VSV-EGFP复制的影响,并通过qPCR法验证IFN下游基因的表达。结果质粒pCK-hIC经双酶切及测序鉴定证明构建正确。表达的hIC蛋白相对分子质量约27000,能明显降低VSV-EGFP的荧光表达,明显抑制病毒增殖,并可激活IFN刺激基因15(interferon-stimulated gene 15,ISG15)、2′-5′寡腺苷酸合成酶1(2′-5′-oligoadenylate synthetase 1,OAS1)、IFN诱导跨膜蛋白(interferon-inducible transmembrane protein,IFITM)的表达。结论hIC具有良好的抗病毒效果,为后续研究及开发奠定了基础。 展开更多
关键词 集成干扰素 序列 干扰素Α 抗病毒
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部