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Temperature and Precipitation Change over South China in CMIP5 and CMIP6 Models:Historical Simulation and Future Projection
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作者 Dongdong PENG Tianjun ZHOU +3 位作者 Sheng HU Lixia ZHANG Jiayu ZHENG Jingxuan QU 《Advances in Atmospheric Sciences》 2025年第7期1423-1441,共19页
Revealing regional climate changes is vital for policymaking activities related to climate change adaptation and mitigation.South China is a well-developed region with a dense population,but the level of uncertainty i... Revealing regional climate changes is vital for policymaking activities related to climate change adaptation and mitigation.South China is a well-developed region with a dense population,but the level of uncertainty in climate projections remains to be evaluated in detail.In this study,we comprehensively assessed the historical simulations and future projections of climate change in South China based on CMIP5/CMIP6 models.We show evidence that CMIP5/CMIP6 models can skillfully reproduce the observed distributions of annual/seasonal mean temperature but show much lower skill for precipitation.CMIP6 outperforms CMIP5 in the historical simulations,as evidenced by more models with lower bias magnitude and higher skill scores.During 2021–2100,the annual mean temperature over South China is projected to increase significantly at a rate of 0.53(0.42–0.63)and 0.59(0.52–0.66)℃(10 yr)^(-1),while precipitation is projected to increase slightly at a rate of 0.78(0.15–1.56)and 1.52(0.91–2.30)%(10 yr)^(-1),under the RCP8.5 and SSP5-8.5 scenarios,respectively.CMIP6 models project larger annual/seasonal mean temperature and precipitation trends than CMIP5 models under equivalent scenarios.The temperature in South China is projected to increase robustly by more than1.5℃during 2041–2060 under RCP4.5 and SSP2-4.5,but by 4.5℃during 2081–2100,under RCP8.5 and SSP5-8.5 with respect to 1850–1900.The uncertainty in temperature projections is mainly dominated by model uncertainty and scenario uncertainty,while internal uncertainty contributes some of the uncertainty during the near-term.The uncertainty in precipitation projection stems mainly from internal uncertainty and model uncertainty.For both the temperature and precipitation projection uncertainty,the relative sizes of contributions from the main contributors vary with time and show obvious seasonal differences. 展开更多
关键词 projection uncertainty model performance CMIP6 South China
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Simulated Asymmetric Connection of SST in the Tasman Sea with Respect to the Opposite Phases of ENSO in Austral Summer in CMIP6 Models
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作者 Hui CAI Xueqian SUN Shuanglin LI 《Advances in Atmospheric Sciences》 2025年第9期1833-1849,共17页
A prior observational study indicated an asymmetric link between sea surface temperature(SST)in the Tasman Sea and ENSO during austral summer.Specifically,El Niño is associated with a dipolar SST anomaly pattern,... A prior observational study indicated an asymmetric link between sea surface temperature(SST)in the Tasman Sea and ENSO during austral summer.Specifically,El Niño is associated with a dipolar SST anomaly pattern,featuring warming in the northwest and cooling in the southeast,whereas La Niña corresponds to basin-scale warming.This study employs the experiments of coupled models from the sixth phase of the Coupled Model Intercomparison Project(CMIP6)to assess ENSO’s impact on Tasman Sea SST.While all 15 models capture the observed dipolar SST anomalies(SSTAs)in the Tasman Sea during El Niño years,only 7 models capture the basin-scale warmth in the Tasman Sea during La Niña years.Consequently,the models are bifurcated into two groups:group-one models yield one physically reasonable asymmetric connection as observed,including the asymmetry of oceanic heat transport,especially the Ekman meridional transport anomalies induced by zonal wind stress driven by the asymmetric atmospheric circulation over the Tasman Sea.However,due to abnormal responses to ENSO and systematic biases in model simulations,including jet and storm tracks,oceanic heat fluxes,ocean currents,and SST,the group-two models fail to reproduce the asymmetric connection between the Tasman Sea and ENSO.This study not only validates the observational asymmetric connection of SSTAs in the Tasman Sea with respect to the two opposite ENSO phases,but also provides evidence and clues to reduce the bias in group-two models. 展开更多
关键词 asymmetric connection SST Tasman Sea ENSO CMIP6 model thermodynamics systematic bias
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A study of ENSO magnitude and lifespan in CMIP6 models
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作者 Siyu Ou De-Zheng Sun Ronghui Zhang 《Acta Oceanologica Sinica》 2025年第9期19-37,共19页
The magnitude of El Nino determines the level of its global impact.Yet,how well our state-of-the-art models simulate this key aspect of El Nino is not well documented.Previous studies tend to ignore El Nino-Southern O... The magnitude of El Nino determines the level of its global impact.Yet,how well our state-of-the-art models simulate this key aspect of El Nino is not well documented.Previous studies tend to ignore El Nino-Southern Oscillation(ENSO)asymmetry and equate the variance of ENSO to the magnitude of El Nino.Moreover,previous evaluations are more focused on the surface manifestation of El Nino.Here,we quantify the magnitudes of El Nino and La Nina separately,both at the surface and subsurface levels.At the surface,we find that while the magnitude of La Nina events in most models is generally stronger than observed,the magnitude of El Nino is more diverse to observations.In fact,in many models,El Nino is weaker than observed.This bias in the magnitude of El Nino is more pronounced in the subsurface.We attribute this weakness in the subsurface to the generally weaker coupling strength and the apparent stronger ENSO at the surface to a lack of sufficiently strong negative feedback from the surface heat flux in the models.When normalized by the variance of ENSO,the lack of exceptionally strong El Nino events in the models is more common and pronounced.We further studied the lifespan of El Nino and La Nina events and have found that multi-year duration is not confined to just La Nina events.There are also El Nino events that last more than one year.Moreover,we have found that multi-year long La Nina events tend to occur over the decades with strong El Nino events.The study also briefly explores the impact of global warming on the duration of ENSO events through the use of a simple model and simulations by CMIP6 models.It has been found that the frequency of multi-year El Nino and La Nina events increases with global warming. 展开更多
关键词 MAGNITUDE LIFESPAN El Nino and La Nina coupled models CMIP6
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Westward shift of western North Pacific tropical cyclones in CMIP6-High Res MIP models
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作者 Zhuoying Li Wen Zhou 《Atmospheric and Oceanic Science Letters》 2025年第2期86-93,共8页
Against the backdrop of climate change,the activity of tropical cyclones(TCs)has captured widespread attention.Observational datasets indicate a declining trend in the genesis longitude of western North Pacific(WNP)TC... Against the backdrop of climate change,the activity of tropical cyclones(TCs)has captured widespread attention.Observational datasets indicate a declining trend in the genesis longitude of western North Pacific(WNP)TCs.This study investigates the zonal changes of WNP TCs with CMIP6-HighResMIP models.These models capture the genesis density of WNP TCs fairly well.The results reveal a westward shift in TC genesis longitude.This trend is associated with the significant reduction in the TC frequency over the southeastern WNP.The study also discusses changes in large-scale circulation patterns and the impact of the strengthening Pacific Walker circulation. 展开更多
关键词 Tropical cyclones Westward shift CMIP6-HighResMIP models Pacific walker circulation
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Differentiated Cloud-Radiation Characteristics over East Asian Subtropical and Tropical Regions Revealed by CMIP6 Models
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作者 WU Rui-xue LI Jian-dong +4 位作者 XU Jian-jun ZHANG Yu LIAO Xiao-qing LIU Chun-lei DU Zhen-cai 《Journal of Tropical Meteorology》 2025年第1期43-63,共21页
Pronounced climatic differences occur over subtropical South China(SC)and tropical South China Sea(SCS)and understanding the key cloud-radiation characteristics is essential to simulating East Asian climate.This study... Pronounced climatic differences occur over subtropical South China(SC)and tropical South China Sea(SCS)and understanding the key cloud-radiation characteristics is essential to simulating East Asian climate.This study investigated cloud fractions and cloud radiative effects(CREs)over SC and SCS simulated by CMIP6 atmospheric models.Remarkable differences in cloud-radiation characteristics appeared over these two regions.In observations,considerable amounts of low-middle level clouds and cloud radiative cooling effect appeared over SC.In contrast,high clouds prevailed over SCS,where longwave and shortwave CREs offset each other,resulting in a weaker net cloud radiative effect(NCRE).The models underestimated NCRE over SC mainly due to weaker shortwave CRE and less cloud fractions.Conversely,most models overestimated NCRE over SCS because of stronger shortwave CRE and weaker longwave CRE.Regional CREs were closely linked to their dominant cloud fractions.Both observations and simulations showed a negative spatial correlation between total(low)cloud fraction and shortwave CRE over SC,especially in winter,and exhibited a positive correlation between high cloud fraction and longwave CRE over these two regions.Compared with SCS,most models overestimated the spatial correlation between low(high)cloud fraction and SWCRE(LWCRE)over SC,with larger bias ranges among models,indicating the exaggerated cloud radiative cooling(warming)effect caused by low(high)clouds.Moreover,most models struggled to describe regional ascent and its connection with CREs over SC while they can better reproduce these connections over SCS.This study further suggests that reasonable circulation conditions are crucial to simulating well cloud-radiation characteristics over the East Asian regions. 展开更多
关键词 cloud fraction cloud radiative effect CMIP6 model South China South China Sea
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An Integrated Experimental-Simulation Calibration Method for the Constitutive Model of 6005A-T6 Aluminum Alloy Welds
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作者 Yu Zhu Lele Zhang +1 位作者 Weiyuan Dou Wen Liu 《Chinese Journal of Mechanical Engineering》 2025年第1期233-245,共13页
Due to the different microstructures caused by the heat source effect,welding joints exhibit significant differences in mechanical properties compared to the base material.Precise characterization of the constitutive ... Due to the different microstructures caused by the heat source effect,welding joints exhibit significant differences in mechanical properties compared to the base material.Precise characterization of the constitutive characteristics of the welded joint requires a large number of repetitive experiments,which are costly,inefficient,and have limited accuracy improvements.This paper proposes an integrated experimental-simulation-based inverse calibration method,which establishes a calibration optimization problem based on the corresponding constitutive model and a finite element calculation model built by the distribution of hardness in the weldment.Using the global tensile force-displacement curve of the MIG-welded 6005A-T6 aluminum alloy specimen and the experimental data of local deformation with time change obtained from DIC(Digital Image Correlation),the parameters involved in the constitutive models are optimized accordingly.This method can directly obtain the constitutive characteristics of the weldment under conditions of limited experiments and insufficient data.Additionally,the adaptability of the constitutive model to the calibration method and the influence of optimization results are discussed and analyzed.The results indicate that the global force-displacement response of the non-saturated Ramberg-Osgood(R-O)model is in the best agreement with that of the experimental data,and the energy error is only 2.62%,followed by the MPL model,while the saturation-based Voce model shows the largest simulation error in terms of the presented object.Furthermore,the simulation results of R-O,Voce,and MPL models in the local area are far superior to traditional fitting methods. 展开更多
关键词 6005A-T6 aluminum alloy MIG-weld joint Parameter calibration Elastic-plastic constitutive model DIC
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6G Digital Twin Enabled Channel Modeling for Beijing Central Business District
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作者 LU Mengyuan BAI Lu +3 位作者 HAN Zengrui HUANG Ziwei LU Shiliang CHENG Xiang 《ZTE Communications》 2025年第2期31-45,共15页
A novel digital twin(DT)enabled channel model for 6G vehicular communications in Beijing Central Business District(Beijing CBD)is proposed,which can support the design of intelligent transportation systems(ITSs).A DT ... A novel digital twin(DT)enabled channel model for 6G vehicular communications in Beijing Central Business District(Beijing CBD)is proposed,which can support the design of intelligent transportation systems(ITSs).A DT space for Beijing CBD is constructed,and two typical transportation periods,i.e.,peak and off-peak hours,are considered to characterize the vehicular communication channel better.Based on the constructed DT space,a DT-enabled vehicular communication dataset is developed,including light detection and ranging(LiDAR)point clouds,RGB images,and channel information.With the assistance of LiDAR point clouds and RGB images,the scatterer parameters,including number,distance,angle,power,and velocity,are analyzed under different transportation periods.The channel non-stationarity and consistency are mimicked in the proposed model.The key channel statistical properties are derived and simulated.Compared to ray-tracing(RT)results,the accuracy of the proposed model is verified. 展开更多
关键词 DT channel modeling 6G vehicular communications Beijing CBD DT-enabled vehicular communication dataset
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Experimental and Neural Network Modeling of the Thermal Behavior of an Agricultural Greenhouse Integrated with a Phase Change Material(CaCl_(2)⋅6H_(2)O)
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作者 Abdelouahab Benseddik Djamel Daoud +4 位作者 Ahmed Badji Hocine Bensaha Tarik Hadibi Yunfeng Wang Li Ming 《Energy Engineering》 2025年第12期5021-5037,共17页
In Saharan climates,greenhouses face extreme diurnal temperature fluctuations that generate thermal stress,reduce crop productivity,and hinder sustainable agricultural practices.Passive thermal storage using Phase Cha... In Saharan climates,greenhouses face extreme diurnal temperature fluctuations that generate thermal stress,reduce crop productivity,and hinder sustainable agricultural practices.Passive thermal storage using Phase Change Materials(PCM)is a promising solution to stabilize microclimatic conditions.This study aims to evaluate experimentally and numerically the effectiveness of PCM integration for moderating greenhouse temperature fluctuations under Saharan climatic conditions.Two identical greenhouse prototypes were constructed in Ghardaia,Algeria:a reference greenhouse and a PCM-integrated greenhouse using calcium chloride hexahydrate(CaCl_(2)⋅6H_(2)O).Thermal performance was assessed during a five-day experimental period(7–11May 2025)under severe ambient conditions.To complement this,a Nonlinear Auto-Regressive with eXogenous inputs(NARX)neural network model was developed and trained using a larger dataset(7–25 May 2025)to predict greenhouse thermal dynamics.The PCM greenhouse reduced peak daytime air temperature by an average of 8.14℃and decreased the diurnal temperature amplitude by 53.6%compared to the reference greenhouse.The NARX model achieved high predictive accuracy(R^(2)=0.990,RMSE=0.425℃,MAE=0.223℃,MBE=0.008℃),capturing both sensible and latent heat transfer mechanisms,including PCM melting and solidification.The combined experimental and predictive modeling results confirm the potential of PCM integration as an effective passive thermal regulation strategy for greenhouses in arid regions.This approach enhances microclimatic stability,improves energy efficiency,and supports the sustainability of protected agriculture under extreme climatic conditions. 展开更多
关键词 Agricultural greenhouse phase changematerial(PCM) CaCl_(2)⋅6H_(2)O thermal regulation NARX neural network experimental study modeling
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“Water”accelerated B(C_(6)F_(5))_(3)-catalyzed Mukaiyama-aldol reaction:Outer-sphere activation model
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作者 Zhenguo Zhang Lanyang Li +6 位作者 Xinlong Zong Yongheng Lv Shuanglei Liu Liang Ji Xuefei Zhao Zhenhua Jia Teck-Peng Loh 《Chinese Chemical Letters》 2025年第7期334-339,共6页
A“water”accelerated metal-free catalytic system has been discovered for the Mukaiyama-aldol reaction.The system involves the use of B(C_(6)F_(5))_(3) as a catalyst,which is water-tolerant and able to activate the ca... A“water”accelerated metal-free catalytic system has been discovered for the Mukaiyama-aldol reaction.The system involves the use of B(C_(6)F_(5))_(3) as a catalyst,which is water-tolerant and able to activate the carbonyl group through a hydrogen bonding network generated by the catalyst.This activation method allows the reactions to be performed with very low catalyst loading,as low as 0.5 mol%.The scope of substrates is broad and a wide variety of functional groups are well tolerated.Diverse aliphatic aldehydes,aromatic aldehydes,unsaturated aldehydes and aromatic ketones coupled with silyl enol ethers/silyl ketone acetals to generate their correspondingβ-hydroxy carbonyl compounds in moderate to good yields.This discovery represents a significant advancement in the field of organic synthesis,as it provides a new,practical and sustainable solution for carbon-carbon bond formation in water. 展开更多
关键词 B(C_(6)F_(5))_(3)-catalysis Hydrogen bonding network Water-acceleration Mukaiyama-aldol reaction Outer-sphere activation model
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18CrNiMo7-6合金钢表面变质层准静态本构参数确定 被引量:1
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作者 徐广涛 李灿 +3 位作者 路留成 张悦 王刚 李凌霄 《机械工程学报》 北大核心 2025年第6期184-193,共10页
基于逐层反演思想,提出一种确定表面变质层准静态本构参数的方法,使用该方法对渗碳热处理之后的18CrNiMo7-6合金钢表面变质层准静态本构参数进行确定。对基体样品进行渗碳热处理,使其表层微观结构发生改变形成表面变质层,进而对渗碳试... 基于逐层反演思想,提出一种确定表面变质层准静态本构参数的方法,使用该方法对渗碳热处理之后的18CrNiMo7-6合金钢表面变质层准静态本构参数进行确定。对基体样品进行渗碳热处理,使其表层微观结构发生改变形成表面变质层,进而对渗碳试样进行化学腐蚀剥层获取含有不同厚度表面变质层的圆棒试样。采用伺服疲劳试验机获取基体以及不同厚度表面变质层试样在25℃,应变率为0.0005s^(-1)下的应力应变关系。选用Johnson-Cook(J-C)本构模型,忽略应变率以及温度的影响,对18CrNiMo7-6合金钢的准静态力学性能进行描述,基于试验数据,结合遗传优化算法,确定表面变质层的J-C模型参数。结果表明,经过渗碳热处理后,试样的弹性模量没有展现出明显的差异,但其屈服强度以及抗拉强度明显增大。对表面变质层进行表征,给出了表面变质层的微观结构信息,从而揭示导致不同厚度表面变质层试样的力学性能展现出明显差异的物理本质。并通过有限元软件LS-DYNA对试样的准静态拉伸试验过程进行有限元模拟,验证了所得参数的可靠性,可为实际工程应用中的数值模拟计算问题提供重要依据。 展开更多
关键词 18CrNiMo7-6合金钢 表面变质层 Johnson-Cook本构模型 拉伸试验 有限元模拟
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18CrNiMo7-6合金钢表面变质层动态本构模型的分层反演方法
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作者 徐广涛 李功 +2 位作者 常晓安 韩光照 赵明皞 《机械强度》 北大核心 2025年第9期54-61,共8页
针对18CrNiMo7-6合金钢表面变质层的静、动态力学行为表征问题,提出表面变质层(Surface-Modified Layer, SML)Johnson-Cook(J-C)本构模型分层反演方法。将SML进行分层处理,开展了含有不同表面变质层厚度的圆柱试样动态压缩试验;通过递... 针对18CrNiMo7-6合金钢表面变质层的静、动态力学行为表征问题,提出表面变质层(Surface-Modified Layer, SML)Johnson-Cook(J-C)本构模型分层反演方法。将SML进行分层处理,开展了含有不同表面变质层厚度的圆柱试样动态压缩试验;通过递进式参数反演,分别确定了SML各层深处的应变率敏感系数C;结合SML各层深处不同温度准静态薄板拉伸试验,确定了其对应的屈服强度A、应变硬化系数B、应变硬化指数n及热软化指数m。试验结果表明,18CrNiMo7-6合金钢SML呈明显的应变硬化、应变率强化及温度软化效应。此外,建立了J-C本构模型参数与无量纲深度h/hb(到SML表面的距离/SML有效深度)的关联模型,为后续的复合强化仿真提供支撑。 展开更多
关键词 表面变质层 Johnson-Cook本构模型 渗碳 18CrNiMo7-6合金钢
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Assessing the Performance of CMIP6 Models in Simulating Droughts across Global Drylands 被引量:2
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作者 Xiaojing YU Lixia ZHANG +1 位作者 Tianjun ZHOU Jianghua ZHENG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第2期193-208,共16页
Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the curr... Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the current state-of-the-art Coupled Model Intercomparison Project phase 6(CMIP6) models remain unknown. Here, both the strengths and weaknesses of CMIP6 models in simulating droughts and corresponding hydrothermal conditions in drylands are assessed.While the general patterns of simulated meteorological elements in drylands resemble the observations, the annual precipitation is overestimated by ~33%(with a model spread of 2.3%–77.2%), along with an underestimation of potential evapotranspiration(PET) by ~32%(17.5%–47.2%). The water deficit condition, measured by the difference between precipitation and PET, is 50%(29.1%–71.7%) weaker than observations. The CMIP6 models show weaknesses in capturing the climate mean drought characteristics in drylands, particularly with the occurrence and duration largely underestimated in the hyperarid Afro-Asian areas. Nonetheless, the drought-associated meteorological anomalies, including reduced precipitation, warmer temperatures, higher evaporative demand, and increased water deficit conditions, are reasonably reproduced. The simulated magnitude of precipitation(water deficit) associated with dryland droughts is overestimated by 28%(24%) compared to observations. The observed increasing trends in drought fractional area,occurrence, and corresponding meteorological anomalies during 1980–2014 are reasonably reproduced. Still, the increase in drought characteristics, associated precipitation and water deficit are obviously underestimated after the late 1990s,especially for mild and moderate droughts, indicative of a weaker response of dryland drought changes to global warming in CMIP6 models. Our results suggest that it is imperative to employ bias correction approaches in drought-related studies over drylands by using CMIP6 outputs. 展开更多
关键词 DROUGHTS hydrothermal conditions DRYLANDS CMIP6 model evaluation
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Spatiotemporal Evaluation and Future Projection of Diurnal Temperature Range over the Tibetan Plateau in CMIP6 Models 被引量:1
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作者 Suguo ZHANG Qin HU +2 位作者 Xianhong MENG Yaqiong LÜ Xianyu YANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第11期2245-2258,共14页
The diurnal temperature range(DTR)serves as a vital indicator reflecting both natural climate variability and anthropogenic climate change.This study investigates the historical and projected multitemporal DTR variati... The diurnal temperature range(DTR)serves as a vital indicator reflecting both natural climate variability and anthropogenic climate change.This study investigates the historical and projected multitemporal DTR variations over the Tibetan Plateau.It assesses 23 climate models from phase 6 of the Coupled Model Intercomparison Project(CMIP6)using CN05.1 observational data as validation,evaluating their ability to simulate DTR over the Tibetan Plateau.Then,the evolution of DTR over the Tibetan Plateau under different shared socioeconomic pathway(SSP)scenarios for the near,middle,and long term of future projection are analyzed using 11 selected robustly performing models.Key findings reveal:(1)Among the models examined,BCC-CSM2-MR,EC-Earth3,EC-Earth3-CC,EC-Earth3-Veg,EC-Earth3-Veg-LR,FGOALS-g3,FIO-ESM-2-0,GFDL-ESM4,MPI-ESM1-2-HR,MPI-ESM1-2-LR,and INM-CM5-0 exhibit superior integrated simulation capability for capturing the spatiotemporal variability of DTR over the Tibetan Plateau.(2)Projection indicates a slightly increasing trend in DTR on the Tibetan Plateau in the SSP1-2.6 scenario,and decreasing trends in the SSP2-4.5,SSP3-7.0,and SPP5-8.5 scenarios.In certain areas,such as the southeastern edge of the Tibetan Plateau,western hinterland of the Tibetan Plateau,southern Kunlun,and the Qaidam basins,the changes in DTR are relatively large.(3)Notably,the warming rate of maximum temperature under SSP2-4.5,SSP3-7.0,and SPP5-8.5 is slower compared to that of minimum temperature,and it emerges as the primary contributor to the projected decrease in DTR over the Tibetan Plateau in the future. 展开更多
关键词 Tibetan Plateau CMIP6 models diurnal temperature range model assessment historical period future projection
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小儿支原体肺炎合并腹泻对IL-4/IL-6等细胞因子的影响及预测模型的构建与验证
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作者 赵婵 高原 《广东医学》 2025年第5期653-658,共6页
目的 探究小儿支原体肺炎合并腹泻对白细胞介素(IL)-4/IL-6等细胞因子的影响,构建并发腹泻的列线图预测模型,并进行验证。方法 纳入于2021年9月至2023年9月诊治的支原体肺炎患儿为研究对象,采用随机数字表法随机抽取临床资料完整的患儿... 目的 探究小儿支原体肺炎合并腹泻对白细胞介素(IL)-4/IL-6等细胞因子的影响,构建并发腹泻的列线图预测模型,并进行验证。方法 纳入于2021年9月至2023年9月诊治的支原体肺炎患儿为研究对象,采用随机数字表法随机抽取临床资料完整的患儿300例,分为建模集200例及验证集100例;根据是否并发腹泻分为两组,建模集中不腹泻组150例,腹泻组50例;验证集中不腹泻组76例,腹泻组24例,收集临床数据,采用受试者工作特征(ROC)曲线分析连续性变量的预测价值;采用logistic回归分析相关因素;采用R语言构建Nomogram预测模型;采用ROC、校准曲线和决策曲线评价模型;并分析相关细胞因子的变化。结果 与不腹泻组相比,发热峰值≥40℃、低补体状态腹泻组占比更多(P<0.05),病程、发热持续时间、抗生素应用时间、IL-4、IL-6、肿瘤坏死因子-α(TNF-α)水平腹泻组均更大(P<0.05),为危险性因素。由此类因素构建的列线图预测模型区分能力较强且预测小儿支原体肺炎合腹泻风险效果良好,其C指数为0.997(0.992~1.003);且DCA结果显示,当其风险阅值>0.12时,该模型可以较好地提供标准化净收益,模型表现良好。结论 发热峰值是否≥40℃、是否为低补体状态腹泻组更少,病程、发热持续时间、抗生素应用时间、IL-4、IL-6、TNF-α水平为危险性因素,且模型拥有较好的预测能力。 展开更多
关键词 小儿支原体肺炎 白细胞介素-4 白细胞介素-6 预测模型
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The bio-active components of the Mongolian medicine Horcha-6 and therapeutic mechanism in the rat migraine model 被引量:1
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作者 Ao Qier Naren Mandula +7 位作者 Qiburi Qiburi Manda Manda Tegexi Baiyin Xilinqiqige Bao Huricha Baigued Chang-Shan Wang Temuqile Temuqile De-Zhi Yang 《Traditional Medicine Research》 2024年第2期8-17,共10页
Background:The active components of Horcha-6 were identified using liquid chromatography with tandem mass spectrometry.Also,we investigated the potential mechanisms that explain why Horcha-6 may be effective in treati... Background:The active components of Horcha-6 were identified using liquid chromatography with tandem mass spectrometry.Also,we investigated the potential mechanisms that explain why Horcha-6 may be effective in treating migraines through the use of network pharmacology and a rat migraine model.Methods:After identifying the active components of Horcha-6,the corresponding genes of the active components’target were obtained from the Universal Protein database,and a“compound-target-disease”network was constructed using Cytoscape 3.9.0 software.For the in vivo experiments,nitroglycerin was injected intraperitoneally into rats to create a migraine model.Pre-treatment with Horcha-6 was administered orally for 14 days,and rats were subjected to migraine-related behavior tests.RNA sequencing was performed to identify the gene expression regulated by Horcha-6 in the trigeminal nerve.Results:A total of 903 chemical components of Horcha-6 have been collected in the liquid chromatography with tandem mass spectrometry.We discovered 55 of the Horcha-6 bio-active components that were evaluated based on their Percent Human Oral Absorption(≥30%)and DL values(≥0.185)on the traditional Chinese medicine systems pharmacology database.The“compound-target-disease”network contained 163 intersection targets with the migraine state.Gene Ontology analysis indicated that these components significantly regulated the immune response,vascular function,oxidative stress,etc.When Kyoto Encyclopedia of Genes and Genomes enrichment analysis was performed,we observed that most of the target genes were significantly enriched in the inflammation and neuro-related signaling pathway,toll-like receptor signaling pathway,neuroactive ligand-receptor interaction,etc.These predictions were further demonstrated via in vivo animal model experiments.The RNA sequencing results showed that 41 genes were down-regulated(P<0.05)and 86 genes were up-regulated(P<0.05)in the Horcha-6 treated group compared with the untreated group.Those genes were mainly involved in neuromodulation,vascular function,and hormone metabolism.Conclusion:The 55 bio-active components in Horcha-6 regulate inflammation,hormone metabolism,and neurotransmitters and have potential as a therapy to treat migraines. 展开更多
关键词 Horcha-6 bio-active components rat migraine model inflammation hormone metabolism NEUROTRANSMITTER
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A Probabilistic Trust Model and Control Algorithm to Protect 6G Networks against Malicious Data Injection Attacks in Edge Computing Environments 被引量:1
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作者 Borja Bordel Sánchez Ramón Alcarria Tomás Robles 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第10期631-654,共24页
Future 6G communications are envisioned to enable a large catalogue of pioneering applications.These will range from networked Cyber-Physical Systems to edge computing devices,establishing real-time feedback control l... Future 6G communications are envisioned to enable a large catalogue of pioneering applications.These will range from networked Cyber-Physical Systems to edge computing devices,establishing real-time feedback control loops critical for managing Industry 5.0 deployments,digital agriculture systems,and essential infrastructures.The provision of extensive machine-type communications through 6G will render many of these innovative systems autonomous and unsupervised.While full automation will enhance industrial efficiency significantly,it concurrently introduces new cyber risks and vulnerabilities.In particular,unattended systems are highly susceptible to trust issues:malicious nodes and false information can be easily introduced into control loops.Additionally,Denialof-Service attacks can be executed by inundating the network with valueless noise.Current anomaly detection schemes require the entire transformation of the control software to integrate new steps and can only mitigate anomalies that conform to predefined mathematical models.Solutions based on an exhaustive data collection to detect anomalies are precise but extremely slow.Standard models,with their limited understanding of mobile networks,can achieve precision rates no higher than 75%.Therefore,more general and transversal protection mechanisms are needed to detect malicious behaviors transparently.This paper introduces a probabilistic trust model and control algorithm designed to address this gap.The model determines the probability of any node to be trustworthy.Communication channels are pruned for those nodes whose probability is below a given threshold.The trust control algorithmcomprises three primary phases,which feed themodel with three different probabilities,which are weighted and combined.Initially,anomalous nodes are identified using Gaussian mixture models and clustering technologies.Next,traffic patterns are studied using digital Bessel functions and the functional scalar product.Finally,the information coherence and content are analyzed.The noise content and abnormal information sequences are detected using a Volterra filter and a bank of Finite Impulse Response filters.An experimental validation based on simulation tools and environments was carried out.Results show the proposed solution can successfully detect up to 92%of malicious data injection attacks. 展开更多
关键词 6G networks noise injection attacks Gaussian mixture model Bessel function traffic filter Volterra filter
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以党建为引领,打造中医药事业“6+X”发展模式
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作者 高小明 战婉青 +1 位作者 刘佳彧 陈陆 《实用中医内科杂志》 2025年第9期140-142,143,共4页
在新时代背景下,坚持和加强党的全面领导是推动中医药事业传承创新发展的根本保障,为中医药事业沿着正确方向前行筑牢了坚实根基。文章以辽宁中医药大学及其附属医院作为典型研究样本,深度聚焦党建引领中医药高质量发展这一核心命题。... 在新时代背景下,坚持和加强党的全面领导是推动中医药事业传承创新发展的根本保障,为中医药事业沿着正确方向前行筑牢了坚实根基。文章以辽宁中医药大学及其附属医院作为典型研究样本,深度聚焦党建引领中医药高质量发展这一核心命题。阐释了发挥党的领导核心作用的关键意义,确保中医药事业发展始终与党的方针政策同频共振;强调强化党支部战斗堡垒功能,使其成为凝聚力量、推动工作的重要阵地;注重激发党员先锋模范作用,以党员的示范引领带动全体中医药工作者积极进取;严格落实党管干部与党管人才原则,为中医药事业选拔和培养德才兼备的骨干力量。在此基础上,文章创新性提出并探索构建了以党建为引领的中医药事业“6+X”发展模式。该模式通过一系列系统性实践创新举措,致力于破解中医药事业发展中面临的资源整合、创新驱动等难题,充分激发中医药事业的内生动力。期望通过此模式的研究与实践,为全面提升中医药服务能力、促进中医药事业高质量发展提供切实可行的理论框架与实践方案,推动中医药在新时代焕发出新的生机与活力。 展开更多
关键词 党建引领 中医药事业 6+X发展模式 高质量发展
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地方高校大学生核心素养“1+6”模式的实践探究——以湖北第二师范学院为例
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作者 张炜 《湖北第二师范学院学报》 2025年第9期78-84,共7页
探索地方高校学生核心素养培育特色模式是湖北第二师范学院落实国家教育“立德树人”根本任务、细化“三全育人”运作机制的综合改革和重要举措。经过十多年的实践探索和经验反思,学校构建出大学生核心素养“1+6”模式,实现了新时代“... 探索地方高校学生核心素养培育特色模式是湖北第二师范学院落实国家教育“立德树人”根本任务、细化“三全育人”运作机制的综合改革和重要举措。经过十多年的实践探索和经验反思,学校构建出大学生核心素养“1+6”模式,实现了新时代“五育”并举的价值对标,并通过“内外结合”的多元评价机制改革和“1+1+1”支撑体系确保了其培育运作的有效性。 展开更多
关键词 大学生核心素养 “1+6”模式 “五育”并举 “1+1+1”支撑体系
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CMIP 6 models simulation of the connection between North/South Pacific Meridional Mode and ENSO 被引量:1
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作者 Yunlong LU Junqiao FENG Dunxin HU 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第2期439-453,共15页
The subtropical North and South Pacific Meridional Modes(NPMM and SPMM)are well known precursors of El Niño-Southern Oscillation(ENSO).However,relationship between them is not constant.In the early 1980,the relat... The subtropical North and South Pacific Meridional Modes(NPMM and SPMM)are well known precursors of El Niño-Southern Oscillation(ENSO).However,relationship between them is not constant.In the early 1980,the relationship experienced an interdecadal transition.Changes in this connection can be attributed mainly to the phase change of the Pacific decadal oscillation(PDO).During the positive phase of PDO,a shallower thermocline in the central Pacific is responsible for the stronger trade wind charging(TWC)mechanism,which leads to a stronger equatorial subsurface temperature evolution.This dynamic process strengthens the connection between NPMM and ENSO.Associated with the negative phase of PDO,a shallower thermocline over southeastern Pacific allows an enhanced wind-evaporation-SST(WES)feedback,strengthening the connection between SPMM and ENSO.Using 35 Coupled Model Intercomparison Project Phase 6(CMIP6)models,we examined the NPMM/SPMM performance and its connection with ENSO in the historical runs.The great majority of CMIP6 models can reproduce the pattern of NPMM and SPMM well,but they reveal discrepant ENSO and NPMM/SPMM relationship.The intermodal uncertainty for the connection of NPMM-ENSO is due to different TWC mechanism.A stronger TWC mechanism will enhance NPMM forcing.For SPMM,few models can simulate a good relationship with ENSO.The intermodel spread in the relationship of SPMM and ENSO owing to SST bias in the southeastern Pacific,as WES feedback is stronger when the southeastern Pacific is warmer. 展开更多
关键词 North and South Pacific Meridional Modes(NPMM and SPMM) El Niño-Southern Oscillation(ENSO) Pacific decadal oscillation(PDO) Coupled model Intercomparison Project Phase 6(CMIP6)
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基于CMIP6模式解析未来水资源变化对引滦入津工程的影响 被引量:1
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作者 王粼昊 张婷 +1 位作者 李建柱 冯平 《水资源与水工程学报》 北大核心 2025年第1期29-39,共11页
为揭示未来水资源变化对引滦入津工程的影响,基于地理空间与水文气象数据,构建了滦河潘家口水库控制流域的SWAT模型。选取4个单项指标和1个综合指标对采用的8个GCMs逐站点进行适用性评估,并依据评估结果进行加权多模式集合,以改进的Delt... 为揭示未来水资源变化对引滦入津工程的影响,基于地理空间与水文气象数据,构建了滦河潘家口水库控制流域的SWAT模型。选取4个单项指标和1个综合指标对采用的8个GCMs逐站点进行适用性评估,并依据评估结果进行加权多模式集合,以改进的Delta-DCSI对气象数据进行降尺度及偏差校正,同时保留了其趋势信号,将修正后的气象数据用于驱动SWAT模型,对未来情景下水资源变化情况进行了模拟预测。结果表明:构建的SWAT模型适用性良好,模式优选后的多模式集合数据精度能够满足驱动SWAT模型进行未来水资源变化预估的要求;未来3种气候情景下径流量年际间变化剧烈,波动起伏较大,总体呈现增大趋势;与1997—2022年相比,潘家口水库入库径流量在未来时期显著增大,流域内水量丰沛,天津市对引滦水量依赖性下降。 展开更多
关键词 水资源 降尺度 CMIP6 SWAT模型 引滦入津
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