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壳聚糖胶原生物敷料对深Ⅱ度烧伤创面NO和NOS的影响 被引量:3
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作者 王秀芹 王晓芹 +3 位作者 李晓辉 周见至 唐渊 张海港 《中国比较医学杂志》 CAS 2004年第1期9-12,共4页
目的 研究壳聚糖胶原生物敷料 (chitosan collagenbiologicaldressing,CCBD)对大鼠深Ⅱ度烧伤创面一氧化氮 (nitricoxide ,NO)和一氧化氮合酶 (nitricoxidesynthase ,NOS)的影响及在创面愈合中的意义。方法 壳聚糖与鼠尾胶原分别按 1... 目的 研究壳聚糖胶原生物敷料 (chitosan collagenbiologicaldressing,CCBD)对大鼠深Ⅱ度烧伤创面一氧化氮 (nitricoxide ,NO)和一氧化氮合酶 (nitricoxidesynthase ,NOS)的影响及在创面愈合中的意义。方法 壳聚糖与鼠尾胶原分别按 1∶9和 1∶1配成敷料原液并制成CCBDA和CCBDB。以单纯胶原敷料组和自然愈合组作对照 ,测定大鼠 10 %深Ⅱ度烫伤后 3、7、14、2 1d的创面愈合率、创面组织蛋白和羟脯氨酸含量、NO含量和NOS活性。结果 CCBDA、B组创面愈合率较自然愈合组高 (P <0 0 5 ,0 0 1) ,CCBDB组伤后 3d和 7d时NO含量和NOS活性低于自然愈合组 (P <0 0 5 ,0 0 1)。结论 CCBD对大鼠深Ⅱ度烧伤创面有促愈合作用并呈剂量相关性 。 展开更多
关键词 壳聚糖胶原生物敷料 ccbd 深Ⅱ度烧伤 创面 NOS 一氧化氮 生化指标
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中心裂纹巴西圆盘压缩载荷下T应力研究 被引量:7
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作者 李一凡 董世明 华文 《岩土力学》 EI CAS CSCD 北大核心 2016年第11期3191-3196,共6页
为了研究中心裂纹巴西圆盘试件在压缩载荷作用下T应力的解析计算方法,通过权函数法推导出集中载荷作用下T应力的显式表达式,进而得到分布载荷作用下的T应力表达式。与边界配位法进行对比,所得公式优点在于任意相对裂纹长度和任意加载角... 为了研究中心裂纹巴西圆盘试件在压缩载荷作用下T应力的解析计算方法,通过权函数法推导出集中载荷作用下T应力的显式表达式,进而得到分布载荷作用下的T应力表达式。与边界配位法进行对比,所得公式优点在于任意相对裂纹长度和任意加载角下的T应力值都能较容易的精确得到。进一步分析表明,分布载荷与集中载荷作用下T应力的偏差随着载荷分布角的增加而增加。集中载荷作用下,相对裂纹长度固定时,T应力随着加载角的增大而增大。中心裂纹巴西圆盘纯I型与纯II型断裂试验时,大多数情况下的T应力都为负值。T应力值对中心裂纹巴西圆盘测定断裂韧度试验有影响,想要通过使T应力为0来消除这种影响是很难达到目的的。 展开更多
关键词 中心裂纹巴西圆盘 权函数法 T应力 解析解
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Experimental Study on Mixed-Mode(Ⅰ–Ⅱ)Fracture Toughness of Freshwater Ice
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作者 Yaozhong Xu Mao Zhou +4 位作者 Xian Yi Wen Hua Jiuzhou Huang Wenyu Zhang Shiming Dong 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2024年第2期252-264,共13页
In recent years,the issue of aircraft icing has gained widespread recognition.The breaking and detachment of dynamic ice can pose a threat to flight safety.However,the shedding and fracture mechanisms of dynamic ice a... In recent years,the issue of aircraft icing has gained widespread recognition.The breaking and detachment of dynamic ice can pose a threat to flight safety.However,the shedding and fracture mechanisms of dynamic ice are unclear and cannot meet the engineering needs of ice-shedding hazard assessment.Therefore,studying the fracture toughness of ice bodies has extremely important practical significance.To address this issue,this article uses a centrally cracked Brazilian disk(CCBD)specimen to measure the pure modeⅠtoughness and pure modeⅡfracture toughness of freshwater ice at different loading rates.The mixed-mode(Ⅰ–Ⅱ)fracture characteristics of ice are discussed,and the experimental results are compared and analyzed with the theoretical values of the generalized maximum tangential stress(GMTS)criterion considering the influence of T-stress.The results indicated that as the loading rate increases,the pure modeⅠtoughness and pure modeⅡfracture toughness of freshwater ice decrease,and the fracture toughness of freshwater ice is more sensitive to the loading rate.Ⅰn terms of fracture criteria,the theoretical value of the ratio of pure modeⅡfracture toughness to pure modeⅠfracture toughness based on the GMTS criterion is in good agreement with the experimental value,while the theoretical value based on the maximum tangential stress(MTS)criterion deviates significantly from the experimental value,indicating that the GMTS criterion considering the influence of T-stress can better predict the experimental results. 展开更多
关键词 Freshwater ice Fracture criteria Centrally cracked Brazilian disk(ccbd) Mixed-mode(Ⅰ-Ⅱ) Loading rate
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Determination of T-stress using finite element analysis 被引量:2
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作者 TANG ShiBin DONG Zuo HUANG RunQiu 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2017年第8期1211-1220,共10页
A method that uses finite element analysis to determine the non-singular stress (T-stress) at a crack tip is proposed in this study. T-stress includes two components: the Tx-stress parallel to the tangent of the cr... A method that uses finite element analysis to determine the non-singular stress (T-stress) at a crack tip is proposed in this study. T-stress includes two components: the Tx-stress parallel to the tangent of the crack at its tip and the Ty-stress perpendicular to this tangent. The effects of contact and friction on both the Tx- and Ty-stresses on the crack flanks are considered in the method. Because the method uses a single standard elastic finite element analysis derived directly from the equation of the stress fields around the crack tip and does not require any assumptions or simplification, it can be used to determine the T-stress for any given geometry and loading condition. Theoretical results are used to calibrate the results, which exhibited good agreement and to discuss the T-stress computational methodology. Furthermore, the Tx- and Ty-stresses in center-cracked Brazilian disc (CCBD) specimens subjected to diametrical or partially distributed compression were numerically computed, and the effects of contact and friction on the Tx- and Ty-stresses are discussed. 展开更多
关键词 T-STRESS finite element ccbd specimen
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