Background: Hepatic angiosarcoma is a rare disease with a poor prognosis due to its tendency for distant sites. Few opportunities exist for palliative treatment of hepatic angiosarcomas at home. Here, we report a rare...Background: Hepatic angiosarcoma is a rare disease with a poor prognosis due to its tendency for distant sites. Few opportunities exist for palliative treatment of hepatic angiosarcomas at home. Here, we report a rare case of palliative treatment of hepatic angiosarcoma at home. Case Presentation: An 87-year-old male patient complained of upper abdominal pain and anorexia, persisting for 2 months. Computed tomography revealed multiple tumors in the liver, spleen, left kidney, and bone. Hepatic angiosarcoma was diagnosed based on the liver biopsy results. Due to his advanced age and dementia, the patient and his family decided to receive palliative treatment at home, thereby initiating home medical care at our clinic. During the first visit, oral opioid medication was introduced, and home oxygen therapy (HOT) was initiated because of complaints of cancer pain and respiratory distress. As oral intake became difficult, the patient was switched to a patch opioid, and suppositories were used for ton use. The patient was treated with morphine and HOT;however, the improvement in respiratory distress was below acceptable. The patient died at home on the ninth day after his visit. Conclusion: To the best of our knowledge, this is the first case report on palliative care for hepatic angiosarcoma at home. Owing to the rapid progression of this disease, home physicians must know its characteristics and provide appropriate medical care.展开更多
[目的]针对现有海洋科学数据存在多源异构、质量参差不齐、交互性低等问题,对海洋科学数据治理框架进行研究,以推动海洋科学数据的开放共享与权益保护,实现数据共享可持续发展.[方法]参照国际海洋观测计划规范,融合FAIR原则(findable,ac...[目的]针对现有海洋科学数据存在多源异构、质量参差不齐、交互性低等问题,对海洋科学数据治理框架进行研究,以推动海洋科学数据的开放共享与权益保护,实现数据共享可持续发展.[方法]参照国际海洋观测计划规范,融合FAIR原则(findable,accessible,interoperable,reusable,可发现、可获取、可交互和可再利用)和CARE原则(collective benefit,authority to control,responsibility,ethics,集体利益、控制权、责任与伦理),对海洋科学数据进行全生命周期的治理.[结果]本研究基于全生命周期的不同责任主体,构建“FAIR+CARE原则”融合的海洋科学数据治理框架和实施路径,并应用于痕量元素及同位素海洋生物地球化学循环国际研究(GEOTRACES)中国项目的海洋科学数据治理中,实现数据申请与共享“零”拒绝,提高了科学家共享和开放数据的意愿.[结论]这一新框架推动了数据的开放共享与可持续发展,并可推广应用到其他领域的大数据治理中,为我国构建符合国际规范、兼顾技术与伦理责任的数据治理研究提供参考.展开更多
Cyperus esculentus root oil(CEL)is a plant of significant economic value,rich in unsaturated fatty acids like oleic acid,linoleic acid,and linolenic acid.In this study,human dermal fibroblasts(HSF)were used to create ...Cyperus esculentus root oil(CEL)is a plant of significant economic value,rich in unsaturated fatty acids like oleic acid,linoleic acid,and linolenic acid.In this study,human dermal fibroblasts(HSF)were used to create an inflammatory model,and the impact of coldpressed oil from CEL on the secretion of inflammatory factors was assessed.The results showed that CEL significantly inhibited IL-6 and IL-1βthat were secreted by HSF cells induced by tumor necrosis factor-α(TNF-α)(P<0.0001),with inhibition rates of 50.79%and 20.26%,respectively.Furthermore,CEL markedly enhanced the secretion of the anti-inflammatory factor IL-10(P<0.01),with an improvement rate of 94.42%.The study further explored the impact of CEL on collagen type I(Col-I)and hyaluronic acid(HA)secretion in the cells.The results demonstrated that CEL effectively increased Col-I secretion by 26.15%(P<0.0001)and HA by 30.2%(P<0.0001)when it was administered at a maximum safe mass fraction of 6%,which consequently showed its potential anti-aging and moisturizing properties.Additionally,fluorescence real-time quantitative polymerase chain reaction(PCR)experiments confirmed that CEL significantly inhibited the TNF-α-induced expression of IL-6,IL-1β,and matrix metalloproteinases(MMP-1,3,9)in HSF cells,while promoted the mRNA expression levels of IL-10 and hyaluronic acid synthase.This modulation suggested that CEL exerted anti-inflammatory and anti-aging effects.Finally,the oil’s anti-inflammatory,anti-senility,and moisturizing effects were validated through the clinical evaluations.In summary,CEL,as a natural raw material abundant in unsaturated fatty acids,shows promising potential for further development and usage in cosmetics due to its anti-inflammatory,anti-aging,and moisturizing properties in personal care.展开更多
It’s no secret that China has an aging population.Statistics from the Seventh National Population Census in 2020 showed that the country had 190.64 million people aged 65 or above,accounting for13.5 percent of its to...It’s no secret that China has an aging population.Statistics from the Seventh National Population Census in 2020 showed that the country had 190.64 million people aged 65 or above,accounting for13.5 percent of its total population.This proportion is now gradually approaching the internationally recognized threshold of 14 percent for a deeply aging society.China’s rapidly aging and mobility-limited population faces a severe shortage of millions of senior care workers.展开更多
A case of imported severe falciparum malaria with spontaneous splenic rupture was reported in this paper.The patient,an African migrant worker,developed hemolytic anemia,sepsis,thrombocytopenia,coagulation dysfunction...A case of imported severe falciparum malaria with spontaneous splenic rupture was reported in this paper.The patient,an African migrant worker,developed hemolytic anemia,sepsis,thrombocytopenia,coagulation dysfunction,liver failure,renal insufficiency,electrolyte disturbance and other clinical manifestations after returning to the local area.Plasmodium falciparum was found by peripheral blood smearscopy and was diagnosed as severe falciparum malaria.After standardized anti-malaria treatment,plasma exchange+cytokine adsorption therapy,the establishment of“forewarning-forewarning-prevention-emergency”predictive nursing management model,the establishment of an integrated nursing team,the division of medical care is clear,professional knowledge is complementary,after three months of regular follow-up,the patient has no malaria recurrence,no refire,the function of all organs returned to normal.展开更多
Over the past few decades,a hilltop Yi ethnic village in Sichuan Province has been transformed from an isolated and impoverished village to a modern and prosperous community.AT this year’s“two sessions,”Zheng Chunw...Over the past few decades,a hilltop Yi ethnic village in Sichuan Province has been transformed from an isolated and impoverished village to a modern and prosperous community.AT this year’s“two sessions,”Zheng Chunwang,a national lawmaker,submitted two proposals:one on improving the elderly care service system in rural areas,and the other one on accelerating the renovation of unsafe rural housing.展开更多
Non-O1/non-O139 Vibrio(V.)cholerae(NOVC)has emerged as a potential pathogen in patients with compromised health conditions[1].We report the whole genome sequencing(WGS)of a rare NOVC sepsis isolate(GenBank Accession:G...Non-O1/non-O139 Vibrio(V.)cholerae(NOVC)has emerged as a potential pathogen in patients with compromised health conditions[1].We report the whole genome sequencing(WGS)of a rare NOVC sepsis isolate(GenBank Accession:GCF_051906115.1)from an 89-year-old male admitted to the Intensive Care Unit(ICU)with septic shock(lactate 6.61 mmol/L)digestive illness.展开更多
Objective:To investigate the effect of dexmedetomidine(DEX)on the incidence of delirium and clinical prognosis in patients with neurosurgical ICU.Methods:This study was a retrospective cohort study that enrolled patie...Objective:To investigate the effect of dexmedetomidine(DEX)on the incidence of delirium and clinical prognosis in patients with neurosurgical ICU.Methods:This study was a retrospective cohort study that enrolled patients admitted to the Neurosurgery ICU of our hospital between January 2021 and December 2023 who required mechanical ventilation(duration>48 hours).Based on sedation protocols,patients were divided into a dexmedetomidine group(DEX group,n=60)and a midazolam routine sedation group(control group,n=60).The primary endpoint was the incidence of delirium during ICU stay,while secondary endpoints included mechanical ventilation duration,ICU length of stay,28-day mortality rate,and adverse events.Results:The incidence of delirium in the DEX group was significantly lower than that in the control group(31.7%vs.58.3%,p=0.004).Additionally,the duration of mechanical ventilation in the DEX group was significantly shorter than that in the control group[(7.2±2.5)days vs.(9.8±3.4)days,p<0.001],and the ICU stay was also significantly reduced[(13.5±4.2)days vs.(16.8±5.7)days,p=0.002].There were no statistically significant differences in the 28-day mortality rate(DEX group:13.3%vs.control group:16.7%,p=0.59)or the rate of unintended extubation(DEX group:3.3%vs.control group:5.0%,p=0.64)between the two groups.In terms of safety,the incidence of bradycardia was significantly higher in the DEX group than in the control group(15.0%vs.3.3%,p=0.03).Conclusion:In neurosurgical patients on mechanical ventilation,dexmedetomidine sedation can effectively reduce the incidence of delirium and shorten the duration of mechanical ventilation and ICU stay,but the potential risk of bradycardia should be monitored.展开更多
In a world growing ever more cruel and violent as nihilism becomes generalized,a world in which the disintegration of the human assumes dimensions that threaten its very cohesion,the demand for the humanization of the...In a world growing ever more cruel and violent as nihilism becomes generalized,a world in which the disintegration of the human assumes dimensions that threaten its very cohesion,the demand for the humanization of the Western individual asserts itself as an urgent historical task.Among the institutions implicated in this process,education assumes a central role,as it is within it that wonder and critical thinking are gradually eliminated,together with the demand for shared deliberation,coherent meaning,and the tragic dimension of human existence,while an education of cruelty comes to permeate it from end to end.In order to prevent the full entrenchment of evil in the social world,from which only destruction can be expected,a decisive role could be played by caring thinking that would be coordinated with corresponding action and would come to deeply characterize the educational institution.Such a form of thinking was proposed in the second half of the twentieth century and took flesh and bones within the framework of the Philosophy for Children movement.Its contemporary application within educational practice could reactivate phronesis(practical wisdom)and contribute to enabling the Western human being to re-create themselves as a democratic human being-one who desires the creation of a world of freedom,equality,and justice,and who acts accordingly to bring it about:the creation of a compassionate and prudent world,the preservation of which would be the responsibility of all.展开更多
Kenneth Mugweri is a happy man after recently being discharged from the China-Uganda Friendship Hospital in Naguru,located on the outskirts of Uganda’s capital Kampala.
Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 str...Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.展开更多
Background:Continuous care for children with enterostomy and their families has been gaining popularity in China.Objective:To evaluate the feasibility of continuous care for children with enterostomy and their familie...Background:Continuous care for children with enterostomy and their families has been gaining popularity in China.Objective:To evaluate the feasibility of continuous care for children with enterostomy and their families in China.Methods:The PubMed,Web of Science,Embase,Cochrane Library,EBSCO,CNKI,CBM,VIP,and WanFang were searched for clinical trials until December 30,2025.Two reviewers independently searched articles,evaluated quality and extracted data.This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA).Results:33 studies involving 2774 participants were included.The meta-analysis showed that continuous care strategy can significantly reduce the incidence of complications in children with enterostomy(OR=0.20,95%CI=0.16-0.26,p<0.001,I2=0%),effectively improve the family caregiver ability for enterostomy(MD=-10.34,95%CI=-13.82 to-6.85,p<0.001,I2=99%),shorten the time for family members to replace stoma bags(MD=-13.57,95%CI=-19.66 to-7.49,p<0.001,I2=100%),and alleviate negative emotions such as anxiety(SMD=-1.80,95%CI=-2.36 to-1.23,p<0.001,I2=92%)and depression(SMD=-1.54,95%CI=-2.04 to-1.04,p<0.001,I2=89%)in the families of the affected children.Conclusions:Continuous care can reduce complications of enterostomy in children,improve the family caregiver ability for enterostomy and alleviate negative emotions of family members such as anxiety and depression.展开更多
文摘Background: Hepatic angiosarcoma is a rare disease with a poor prognosis due to its tendency for distant sites. Few opportunities exist for palliative treatment of hepatic angiosarcomas at home. Here, we report a rare case of palliative treatment of hepatic angiosarcoma at home. Case Presentation: An 87-year-old male patient complained of upper abdominal pain and anorexia, persisting for 2 months. Computed tomography revealed multiple tumors in the liver, spleen, left kidney, and bone. Hepatic angiosarcoma was diagnosed based on the liver biopsy results. Due to his advanced age and dementia, the patient and his family decided to receive palliative treatment at home, thereby initiating home medical care at our clinic. During the first visit, oral opioid medication was introduced, and home oxygen therapy (HOT) was initiated because of complaints of cancer pain and respiratory distress. As oral intake became difficult, the patient was switched to a patch opioid, and suppositories were used for ton use. The patient was treated with morphine and HOT;however, the improvement in respiratory distress was below acceptable. The patient died at home on the ninth day after his visit. Conclusion: To the best of our knowledge, this is the first case report on palliative care for hepatic angiosarcoma at home. Owing to the rapid progression of this disease, home physicians must know its characteristics and provide appropriate medical care.
文摘[目的]针对现有海洋科学数据存在多源异构、质量参差不齐、交互性低等问题,对海洋科学数据治理框架进行研究,以推动海洋科学数据的开放共享与权益保护,实现数据共享可持续发展.[方法]参照国际海洋观测计划规范,融合FAIR原则(findable,accessible,interoperable,reusable,可发现、可获取、可交互和可再利用)和CARE原则(collective benefit,authority to control,responsibility,ethics,集体利益、控制权、责任与伦理),对海洋科学数据进行全生命周期的治理.[结果]本研究基于全生命周期的不同责任主体,构建“FAIR+CARE原则”融合的海洋科学数据治理框架和实施路径,并应用于痕量元素及同位素海洋生物地球化学循环国际研究(GEOTRACES)中国项目的海洋科学数据治理中,实现数据申请与共享“零”拒绝,提高了科学家共享和开放数据的意愿.[结论]这一新框架推动了数据的开放共享与可持续发展,并可推广应用到其他领域的大数据治理中,为我国构建符合国际规范、兼顾技术与伦理责任的数据治理研究提供参考.
文摘Cyperus esculentus root oil(CEL)is a plant of significant economic value,rich in unsaturated fatty acids like oleic acid,linoleic acid,and linolenic acid.In this study,human dermal fibroblasts(HSF)were used to create an inflammatory model,and the impact of coldpressed oil from CEL on the secretion of inflammatory factors was assessed.The results showed that CEL significantly inhibited IL-6 and IL-1βthat were secreted by HSF cells induced by tumor necrosis factor-α(TNF-α)(P<0.0001),with inhibition rates of 50.79%and 20.26%,respectively.Furthermore,CEL markedly enhanced the secretion of the anti-inflammatory factor IL-10(P<0.01),with an improvement rate of 94.42%.The study further explored the impact of CEL on collagen type I(Col-I)and hyaluronic acid(HA)secretion in the cells.The results demonstrated that CEL effectively increased Col-I secretion by 26.15%(P<0.0001)and HA by 30.2%(P<0.0001)when it was administered at a maximum safe mass fraction of 6%,which consequently showed its potential anti-aging and moisturizing properties.Additionally,fluorescence real-time quantitative polymerase chain reaction(PCR)experiments confirmed that CEL significantly inhibited the TNF-α-induced expression of IL-6,IL-1β,and matrix metalloproteinases(MMP-1,3,9)in HSF cells,while promoted the mRNA expression levels of IL-10 and hyaluronic acid synthase.This modulation suggested that CEL exerted anti-inflammatory and anti-aging effects.Finally,the oil’s anti-inflammatory,anti-senility,and moisturizing effects were validated through the clinical evaluations.In summary,CEL,as a natural raw material abundant in unsaturated fatty acids,shows promising potential for further development and usage in cosmetics due to its anti-inflammatory,anti-aging,and moisturizing properties in personal care.
文摘It’s no secret that China has an aging population.Statistics from the Seventh National Population Census in 2020 showed that the country had 190.64 million people aged 65 or above,accounting for13.5 percent of its total population.This proportion is now gradually approaching the internationally recognized threshold of 14 percent for a deeply aging society.China’s rapidly aging and mobility-limited population faces a severe shortage of millions of senior care workers.
基金“Artificial Liver Special Fund”of Beijing Gan Dan Xiang Zhao Public Welfare Foundation(Project No.:iGandanF-1082024-RGG055)。
文摘A case of imported severe falciparum malaria with spontaneous splenic rupture was reported in this paper.The patient,an African migrant worker,developed hemolytic anemia,sepsis,thrombocytopenia,coagulation dysfunction,liver failure,renal insufficiency,electrolyte disturbance and other clinical manifestations after returning to the local area.Plasmodium falciparum was found by peripheral blood smearscopy and was diagnosed as severe falciparum malaria.After standardized anti-malaria treatment,plasma exchange+cytokine adsorption therapy,the establishment of“forewarning-forewarning-prevention-emergency”predictive nursing management model,the establishment of an integrated nursing team,the division of medical care is clear,professional knowledge is complementary,after three months of regular follow-up,the patient has no malaria recurrence,no refire,the function of all organs returned to normal.
文摘Over the past few decades,a hilltop Yi ethnic village in Sichuan Province has been transformed from an isolated and impoverished village to a modern and prosperous community.AT this year’s“two sessions,”Zheng Chunwang,a national lawmaker,submitted two proposals:one on improving the elderly care service system in rural areas,and the other one on accelerating the renovation of unsafe rural housing.
文摘Non-O1/non-O139 Vibrio(V.)cholerae(NOVC)has emerged as a potential pathogen in patients with compromised health conditions[1].We report the whole genome sequencing(WGS)of a rare NOVC sepsis isolate(GenBank Accession:GCF_051906115.1)from an 89-year-old male admitted to the Intensive Care Unit(ICU)with septic shock(lactate 6.61 mmol/L)digestive illness.
文摘Objective:To investigate the effect of dexmedetomidine(DEX)on the incidence of delirium and clinical prognosis in patients with neurosurgical ICU.Methods:This study was a retrospective cohort study that enrolled patients admitted to the Neurosurgery ICU of our hospital between January 2021 and December 2023 who required mechanical ventilation(duration>48 hours).Based on sedation protocols,patients were divided into a dexmedetomidine group(DEX group,n=60)and a midazolam routine sedation group(control group,n=60).The primary endpoint was the incidence of delirium during ICU stay,while secondary endpoints included mechanical ventilation duration,ICU length of stay,28-day mortality rate,and adverse events.Results:The incidence of delirium in the DEX group was significantly lower than that in the control group(31.7%vs.58.3%,p=0.004).Additionally,the duration of mechanical ventilation in the DEX group was significantly shorter than that in the control group[(7.2±2.5)days vs.(9.8±3.4)days,p<0.001],and the ICU stay was also significantly reduced[(13.5±4.2)days vs.(16.8±5.7)days,p=0.002].There were no statistically significant differences in the 28-day mortality rate(DEX group:13.3%vs.control group:16.7%,p=0.59)or the rate of unintended extubation(DEX group:3.3%vs.control group:5.0%,p=0.64)between the two groups.In terms of safety,the incidence of bradycardia was significantly higher in the DEX group than in the control group(15.0%vs.3.3%,p=0.03).Conclusion:In neurosurgical patients on mechanical ventilation,dexmedetomidine sedation can effectively reduce the incidence of delirium and shorten the duration of mechanical ventilation and ICU stay,but the potential risk of bradycardia should be monitored.
文摘In a world growing ever more cruel and violent as nihilism becomes generalized,a world in which the disintegration of the human assumes dimensions that threaten its very cohesion,the demand for the humanization of the Western individual asserts itself as an urgent historical task.Among the institutions implicated in this process,education assumes a central role,as it is within it that wonder and critical thinking are gradually eliminated,together with the demand for shared deliberation,coherent meaning,and the tragic dimension of human existence,while an education of cruelty comes to permeate it from end to end.In order to prevent the full entrenchment of evil in the social world,from which only destruction can be expected,a decisive role could be played by caring thinking that would be coordinated with corresponding action and would come to deeply characterize the educational institution.Such a form of thinking was proposed in the second half of the twentieth century and took flesh and bones within the framework of the Philosophy for Children movement.Its contemporary application within educational practice could reactivate phronesis(practical wisdom)and contribute to enabling the Western human being to re-create themselves as a democratic human being-one who desires the creation of a world of freedom,equality,and justice,and who acts accordingly to bring it about:the creation of a compassionate and prudent world,the preservation of which would be the responsibility of all.
文摘Kenneth Mugweri is a happy man after recently being discharged from the China-Uganda Friendship Hospital in Naguru,located on the outskirts of Uganda’s capital Kampala.
基金The National Natural Science Foundation of China[72174184]provided policy and financialsupport for this research.
文摘Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.
文摘Background:Continuous care for children with enterostomy and their families has been gaining popularity in China.Objective:To evaluate the feasibility of continuous care for children with enterostomy and their families in China.Methods:The PubMed,Web of Science,Embase,Cochrane Library,EBSCO,CNKI,CBM,VIP,and WanFang were searched for clinical trials until December 30,2025.Two reviewers independently searched articles,evaluated quality and extracted data.This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA).Results:33 studies involving 2774 participants were included.The meta-analysis showed that continuous care strategy can significantly reduce the incidence of complications in children with enterostomy(OR=0.20,95%CI=0.16-0.26,p<0.001,I2=0%),effectively improve the family caregiver ability for enterostomy(MD=-10.34,95%CI=-13.82 to-6.85,p<0.001,I2=99%),shorten the time for family members to replace stoma bags(MD=-13.57,95%CI=-19.66 to-7.49,p<0.001,I2=100%),and alleviate negative emotions such as anxiety(SMD=-1.80,95%CI=-2.36 to-1.23,p<0.001,I2=92%)and depression(SMD=-1.54,95%CI=-2.04 to-1.04,p<0.001,I2=89%)in the families of the affected children.Conclusions:Continuous care can reduce complications of enterostomy in children,improve the family caregiver ability for enterostomy and alleviate negative emotions of family members such as anxiety and depression.
