With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wid...With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wide implementation of relevant standards,and accelerate the globalization process of green product trade through high-level communication.Lyu Xuefeng,Director of Qingdao Institute of Bioenergy and Bioprocess Technology(QIBEBT),Chinese Academy of Sciences,emphasized in his address that the product carbon footprint management system is the important support for industrial green transformation.The geographic information system-life cycle assessment(GIS-LCA)technology has been originally proposed and adopted as the core content of the national standard GB/T 24067-2024,Greenhouse gases-Carbon footprint of products-Requirements and guidelines for quantification.展开更多
腺病毒(Adenovirus,Ad)是一类无包膜的双链DNA病毒,能广泛感染脊椎动物,导致从轻症到严重的感染。腺病毒通过其纤突蛋白与宿主细胞表面受体结合,柯萨奇-腺病毒受体(Coxsackievirus and adenovirus receptor,CAR)是主要的介导者。CAR是...腺病毒(Adenovirus,Ad)是一类无包膜的双链DNA病毒,能广泛感染脊椎动物,导致从轻症到严重的感染。腺病毒通过其纤突蛋白与宿主细胞表面受体结合,柯萨奇-腺病毒受体(Coxsackievirus and adenovirus receptor,CAR)是主要的介导者。CAR是一种高度保守的跨膜蛋白,在多种脊椎动物中发挥关键作用。文章聚焦于CAR的生物学功能和结构特征,探讨其在腺病毒感染机制中的核心作用;重点分析了CAR与人腺病毒、禽腺病毒及其他物种腺病毒的相互作用及功能差异,揭示腺病毒与宿主受体结合的多样性和复杂性。此外,文章讨论了CAR在基因治疗中的应用前景,特别是利用CAR介导的腺病毒载体递送抗癌基因和免疫调节基因的研究进展。同时,调控CAR表达水平及阻断其与病毒结合的策略被认为是优化腺病毒治疗的重要方向。文章通过总结现有研究成果,深化了对腺病毒感染机制的认识,并为基因治疗及相关疾病的治疗策略提供了重要的理论依据和实践参考。展开更多
文摘With the theme of“standardized approaches empowering industrial green and low-carbon transformation”,a sub-forum was held to promote the application of the carbon footprint management system in China,advance the wide implementation of relevant standards,and accelerate the globalization process of green product trade through high-level communication.Lyu Xuefeng,Director of Qingdao Institute of Bioenergy and Bioprocess Technology(QIBEBT),Chinese Academy of Sciences,emphasized in his address that the product carbon footprint management system is the important support for industrial green transformation.The geographic information system-life cycle assessment(GIS-LCA)technology has been originally proposed and adopted as the core content of the national standard GB/T 24067-2024,Greenhouse gases-Carbon footprint of products-Requirements and guidelines for quantification.
文摘腺病毒(Adenovirus,Ad)是一类无包膜的双链DNA病毒,能广泛感染脊椎动物,导致从轻症到严重的感染。腺病毒通过其纤突蛋白与宿主细胞表面受体结合,柯萨奇-腺病毒受体(Coxsackievirus and adenovirus receptor,CAR)是主要的介导者。CAR是一种高度保守的跨膜蛋白,在多种脊椎动物中发挥关键作用。文章聚焦于CAR的生物学功能和结构特征,探讨其在腺病毒感染机制中的核心作用;重点分析了CAR与人腺病毒、禽腺病毒及其他物种腺病毒的相互作用及功能差异,揭示腺病毒与宿主受体结合的多样性和复杂性。此外,文章讨论了CAR在基因治疗中的应用前景,特别是利用CAR介导的腺病毒载体递送抗癌基因和免疫调节基因的研究进展。同时,调控CAR表达水平及阻断其与病毒结合的策略被认为是优化腺病毒治疗的重要方向。文章通过总结现有研究成果,深化了对腺病毒感染机制的认识,并为基因治疗及相关疾病的治疗策略提供了重要的理论依据和实践参考。
