Rockfalls are one of the most dangerous natural events in hilly terrains, and they substantially threaten residential areas and transport corridors in these environments. This study is aimed to analyze the risk of roc...Rockfalls are one of the most dangerous natural events in hilly terrains, and they substantially threaten residential areas and transport corridors in these environments. This study is aimed to analyze the risk of rockfall from a slope to nearby houses in a historical settlement with past rockfall histories. It contains numerous applications to study rockfall danger from different points of view(e.g., kinematics,numerical stability analysis, risk assessment, 2D trajectory). The rockfall kinematics revealed the statistics for different structurally controlled failure modes among the surveyed slope discontinuities,especially wedge type and block toppling were the most significant ones. Finite element analysis showed that the slope was stable under the natural condition with a safety factor of 2.19. The rockfall risk rating system calculated a medium risk for the houses downstream. Based on the field measurements, a possible rockfall profile was determined and located as an input in the 2D rockfall trajectory program. The rigid-body impact model runs utilized various shapes and sizes of blocks to simulate the rockfall events realistically. According to the 2D trajectory model results, there was no rockfall danger for the investigated downslope houses. The study showed the importance of using different analysis techniques to solve rockfall risk in protected areas based on scientific and rational approaches.展开更多
Diabetes mellitus is a group of metabolic diseases involving carbohydrate, lipid, and protein metabolism. It is characterized by persistent hyperglycemia which results from defects in insulin secretion, or action or b...Diabetes mellitus is a group of metabolic diseases involving carbohydrate, lipid, and protein metabolism. It is characterized by persistent hyperglycemia which results from defects in insulin secretion, or action or both. Diabetes mellitus has been known since antiquity. Descriptions have been found in the Egyptian papyri, in ancient Indian and Chinese medical literature, as well as, in the work of ancient Greek and Arab physicians. In the 2^(nd) century AD Aretaeus of Cappadocia provided the first accurate description of diabetes, coining the term diabetes, while in 17^(th) century Thomas Willis added the term mellitus to the disease, in an attempt to describe the extremely sweet taste of the urine. The important work of the 19^(th) century French physiologist Claude Bernard, on the glycogenic action of the liver, paved the way for further progress in the study of the disease. In 1889, Oskar Minkowski and Joseph von Mering performed their famous experiment of removing the pancreas from a dog and producing severe and fatal diabetes. In 1921, Frederick Banting and Charles Best extended Minkowski's and Mering's experiment. They isolated insulin from pancreatic islets and administrated to patients suffering from type 1 diabetes, saving thus the lives of millions and inaugurating a new era in diabetes treatment.展开更多
文摘Rockfalls are one of the most dangerous natural events in hilly terrains, and they substantially threaten residential areas and transport corridors in these environments. This study is aimed to analyze the risk of rockfall from a slope to nearby houses in a historical settlement with past rockfall histories. It contains numerous applications to study rockfall danger from different points of view(e.g., kinematics,numerical stability analysis, risk assessment, 2D trajectory). The rockfall kinematics revealed the statistics for different structurally controlled failure modes among the surveyed slope discontinuities,especially wedge type and block toppling were the most significant ones. Finite element analysis showed that the slope was stable under the natural condition with a safety factor of 2.19. The rockfall risk rating system calculated a medium risk for the houses downstream. Based on the field measurements, a possible rockfall profile was determined and located as an input in the 2D rockfall trajectory program. The rigid-body impact model runs utilized various shapes and sizes of blocks to simulate the rockfall events realistically. According to the 2D trajectory model results, there was no rockfall danger for the investigated downslope houses. The study showed the importance of using different analysis techniques to solve rockfall risk in protected areas based on scientific and rational approaches.
文摘Diabetes mellitus is a group of metabolic diseases involving carbohydrate, lipid, and protein metabolism. It is characterized by persistent hyperglycemia which results from defects in insulin secretion, or action or both. Diabetes mellitus has been known since antiquity. Descriptions have been found in the Egyptian papyri, in ancient Indian and Chinese medical literature, as well as, in the work of ancient Greek and Arab physicians. In the 2^(nd) century AD Aretaeus of Cappadocia provided the first accurate description of diabetes, coining the term diabetes, while in 17^(th) century Thomas Willis added the term mellitus to the disease, in an attempt to describe the extremely sweet taste of the urine. The important work of the 19^(th) century French physiologist Claude Bernard, on the glycogenic action of the liver, paved the way for further progress in the study of the disease. In 1889, Oskar Minkowski and Joseph von Mering performed their famous experiment of removing the pancreas from a dog and producing severe and fatal diabetes. In 1921, Frederick Banting and Charles Best extended Minkowski's and Mering's experiment. They isolated insulin from pancreatic islets and administrated to patients suffering from type 1 diabetes, saving thus the lives of millions and inaugurating a new era in diabetes treatment.
