γ-Secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the ...γ-Secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface receptors.Mutations inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-Secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as well.However,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-secretase.In this review,we focus on recent studies of structural dynamic mechanisms ofγ-secretase.Different mechanisms,including the“Fit-Stay-Trim,”“Sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics simulations.While an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental findings.The approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-secretase.In addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is discussed.Finally,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations of theγ-secretase-substrate complexes.Comprehensive understanding of the functional mechanisms ofγ-secretase will greatly facilitate the rational design of effective drug molecules for treating familial Alzheimer’s disease and perhaps Alzheimer’s disease in general.展开更多
Port structures constitute the main link in the maritime transport chain of coastal countries and therefore contribute to their economic development. But it should be noted that the installation of said works is not w...Port structures constitute the main link in the maritime transport chain of coastal countries and therefore contribute to their economic development. But it should be noted that the installation of said works is not without consequences for the countries concerned. Benin, a country in the Gulf of Guinea, is no exception to this phenomenon because, due to its maritime history, it has a heritage of port structures. These structures, built on its coastline, cause a wide variety of environmental problems such as silting and erosion on either side of them. The general objective of this article is to contribute to the proper functionality of port facilities while minimizing environmental problems that may arise. It aims to provide managers with a tool allowing them to fully understand the state of their assets in order to rationalize maintenance actions. In order to achieve this objective, an assessment of the state of the structure, and then a structural diagnosis are necessary and recommendations can be established to restore the level of service of the latter. As a result, two examples were presented: the wharf of the Sèmè-Podji pipeline project and the maritime piles project of the Wasco de Gama bridge (control project), and recommendations adapted to this objective were established. The comparative analysis of the two examples, both maritime works, revealed an under-sizing at the level of the spans of the wharf bridge of the Sèmè-Podji pipeline project (spans of 7 m in length), while these spans vary on average by 45 m to 62 m for the Wasco da Gama bridge. Bringing the piles closer together at the Sèmè-Podji wharf reduces the energy of the current which promotes the accumulation of sediment. The structure no longer experiences a flow capable of setting in motion the sands accumulated since at least 2022. This element appears to be a fundamental characteristic explaining the erosion observed to the east of the structure.展开更多
NLLoc is a nonlinear search positioning method.In this study,we use simulated arrival time data to quantitatively evaluate the NLLoc method from three aspects:arrival time picking accuracy,station distribution,and vel...NLLoc is a nonlinear search positioning method.In this study,we use simulated arrival time data to quantitatively evaluate the NLLoc method from three aspects:arrival time picking accuracy,station distribution,and velocity model.The results show that the NLLoc method exhibits high positioning accuracy and stability in terms of arrival time picking accuracy and station distribution;however,it is sensitive to the velocity model.The positioning accuracy is higher when the velocity model is smaller than the true velocity.We combined absolute and relative positioning methods.First,we use the NLLoc method for absolute positioning of seismic data and then the double difference positioning method for relative positioning to obtain a more accurate relocation result.Furthermore,we used the combined method to locate the earthquake sequence after collecting dense seismic array data on the Luanzhou M_(S)4.3 earthquake that occurred on April 16,2021,in Hebei Province.By fitting the fault plane with the relocated earthquake sequences,the results show that the strike and dip angles of the seismogenic fault of the Luanzhou M_(S)4.3 earthquake are 208.5°and 85.6°,respectively.This indicates a high-dip angle fault with North-North-East strike and North-West dip directions.Furthermore,we infer that the seismogenic fault of the Luanzhou M_(S)4.3 earthquake is the Lulong fault.展开更多
Proton exchange membrane fuel cells(PEMFCs)constitute a promising avenue for environmentally friendly power generation.However,the reliance on unsustainable platinum-based electrocatalysts used at the electrodes poses...Proton exchange membrane fuel cells(PEMFCs)constitute a promising avenue for environmentally friendly power generation.However,the reliance on unsustainable platinum-based electrocatalysts used at the electrodes poses challenges to the commercial viability of PEMFCs.Non-platinum group metal(non-PGM)alternatives,like nitrogen-coordinated transition metals in atomic dispersion(M–N–C catalysts),show significant potential.This work presents a comparative study of two distinct sets of Fe–N–C materials,prepared by pyrolyzing hybrid composites of polyaniline(PANI)and iron(Ⅱ)chloride on a hard template.One set uses bipyridine(BPy)as an additional nitrogen source and iron ligand,offering an innovative approach.The findings reveal that the choice of pyrolysis temperature and atmosphere influences the catalyst properties.The use of ammonia in pyrolysis emerges as a crucial parameter for promoting atomic dispersion of iron,as well as increasing surface area and porosity.The optimal catalyst,prepared using BPy and ammonia,exhibits a half-wave potential of 0.834 V in 0.5 M H_(2)SO_(4)(catalyst loading of 0.6 mg cm^(-2)),a mass activity exceeding 3 A g^(-1)and high stability in acidic electrolyte,positioning it as a promising non-PGM structure in the field.展开更多
The variations in the mechanical and magnetic properties of cold-rolled 20Mn23AlV non-magnetic structural steel after annealing at different temperatures were investigated.The microstructure and precipitation changes ...The variations in the mechanical and magnetic properties of cold-rolled 20Mn23AlV non-magnetic structural steel after annealing at different temperatures were investigated.The microstructure and precipitation changes during annealing were studied by optical microscopy,scanning electron microscopy,and transmission electron microscopy.The results show that recrystallization completed after annealing at 620℃,resulting in grain sizes of approximately 800 nm and the best combination of strength and plasticity.The yield-to-tensile ratio of the non-magnetic structural steel after cold rolling continuously decreases from low to high temperatures after annealing,with the highest value being 0.89 and the lowest value being 0.43,indicating a wide range of yield-to-tensile ratio adjustment.The introduction of numerous dislocations during cold rolling provided favorable nucleation sites for precipitation,leading to abundant precipitation of the fine second-phase V(C,N).The phase composition of the samples remained unchanged as single-phase austenite after annealing,and the relative permeability values were calculated to be less than 1.002,meeting the requirements for non-magnetic steel in terms of magnetic properties.展开更多
In this study,the casting process is used to fabricate modified polyvinyl alcohol(PVA),starch(S),and carboxymethyl cellulose(CMC)polymer blend films(PVA/S/CMC)loaded with various concentrations of irondoped carbon qua...In this study,the casting process is used to fabricate modified polyvinyl alcohol(PVA),starch(S),and carboxymethyl cellulose(CMC)polymer blend films(PVA/S/CMC)loaded with various concentrations of irondoped carbon quantum dots(Fe-CQDs)and denoted as(PVA/S/CMC@Fe-CQDs).A one-step microwave strategy was employed as a facile method to prepare Fe-CQDs.Through a series of characterization techniques,fourier-transform infrared(FTIR)spectroscopy,x-ray diffraction(XRD)analysis,and scanning electron microscopy(SEM)have been used to show the successful integration of Fe-CQDs into the PVA/S/CMCmatrix.Loading the synthesized Fe-CQDs to the polymeric matrix significantly enhanced the mechanical properties of the films represented in the tensile strength,Young’s modulus,and hardness.However,the elongation decreased noticeably upon increasing the iron-doped carbon dots.The surface wettability was also studied by measuring the contact angle of the prepared films.The findings showed a noticeable elevation in these measurements by increasing the Fe-CQDs content,declaring the role of a hydrophobic character in these nanoparticles when introduced into a hydrophilic polymeric system.The dielectric characteristics of the reinforced polymer composite films were evaluated.These results revealed that the ac-conductivity of the investigated films was boosted with increasing Fe-CQDs’ratio and frequency.The PVA/S/CMC@Fe-CQDs films possess substantial potential for efficient energy storage applications.展开更多
Mo_(2)C is an excellent electrocatalyst for hydrogen evolution reaction(HER).However,Mo_(2)C is a poor electrocatalyst for oxygen evolution reaction(OER).Herein,two different elements,namely Co and Fe,are incorporated...Mo_(2)C is an excellent electrocatalyst for hydrogen evolution reaction(HER).However,Mo_(2)C is a poor electrocatalyst for oxygen evolution reaction(OER).Herein,two different elements,namely Co and Fe,are incorporated in Mo_(2)C that,therefore,has a finely tuned electronic structure,which is not achievable by incorporation of any one of the metals.Consequently,the resulting electrocatalyst Co_(0.8)Fe_(0.2)-Mo_(2)C-80 displayed excellent OER catalytic performance,which is evidenced by a low overpotential of 214.0(and 246.5)mV to attain a current density of 10(and 50)mA cm^(-2),an ultralow Tafel slope of 38.4 mV dec^(-1),and longterm stability in alkaline medium.Theoretical data demonstrates that Co_(0.8)Fe_(0.2)-Mo_(2)C-80 requires the lowest overpotential(1.00 V)for OER and Co centers to be the active sites.The ultrahigh catalytic performance of the electrocatalyst is attributed to the excellent intrinsic catalytic activity due to high Brunauer-Emmett-Teller specific surface area,large electrochemically active surface area,small Tafel slope,and low chargetransfer resistance.展开更多
Intensive management is known to markedly alter soil carbon(C)storage and turnover in Moso bamboo forests compared with extensive management.However,the effects of intensive management on soil respiration(RS)component...Intensive management is known to markedly alter soil carbon(C)storage and turnover in Moso bamboo forests compared with extensive management.However,the effects of intensive management on soil respiration(RS)components remain unclear.This study aimed to evaluate the changes in different RScomponents(root,mycorrhizal,and free-living microorganism respiration)in Moso bamboo forests under extensive and intensive management practices.A1-year in-situ microcosm experiment was conducted to quantify the RScomponents in Moso bamboo forests under the two management practices using mesh screens of varying sizes.The results showed that the total RSand its components exhibited similar seasonal variability between the two management practices.Compared with extensive management,intensive management significantly increased cumulative respiration from mycorrhizal fungi by 36.73%,while decreased cumulative respiration from free-living soil microorganisms by 8.97%.Moreover,the abundance of arbuscular mycorrhizal fungi(AMF)increased by 43.38%,but bacterial and fungal abundances decreased by 21.65%and 33.30%,respectively,under intensive management.Both management practices significantly changed the bacterial community composition,which could be mainly explained by soil pH and available potassium.Mycorrhizal fungi and intensive management affected the interrelationships between bacterial members.Structural equation modeling indicated that intensive management changed the cumulative RSby elevating AMF abundance and lowering bacterial abundance.We concluded that intensive management reduced the microbial respiration-derived C loss,but increased mycorrhizal respiration-derived C loss.展开更多
The impedance matching of absorbers is a vital factor affecting their microwave absorption(MA)properties.In this work,we controllably synthesized Material of Institute Lavoisier 88C(MIL-88C)with varying aspect ratios(...The impedance matching of absorbers is a vital factor affecting their microwave absorption(MA)properties.In this work,we controllably synthesized Material of Institute Lavoisier 88C(MIL-88C)with varying aspect ratios(AR)as a precursor by regulating oil bath conditions,followed by one-step thermal decomposition to obtain carbon-coated iron-based composites.Modifying the precursor MIL-88C(Fe)preparation conditions,such as the molar ratio between metal ions and organic ligands(M/O),oil bath temperature,and oil bath time,influenced the phases,graphitization degree,and AR of the derivatives,enabling low filler loading,achieving well-matched impedance,and ensuring outstanding MA properties.The MOF-derivatives 2(MD_(2))/polyvinylidene Difluoride(PVDF),MD_(3)/PVDF,and MD4/PVDF absorbers all exhibited excellent MA properties with optimal filler loadings below 20 wt%and as low as 5 wt%.The MD_(2)/PVDF(5 wt%)achieved a maximum effective absorption bandwidth(EAB)of 5.52 GHz(1.90 mm).The MD_(3)/PVDF(10 wt%)possessed a minimum reflection loss(RL_(min))value of−67.4 at 12.56 GHz(2.13 mm).A symmetric gradient honeycomb structure(SGHS)was constructed utilizing the high-frequency structure simulator(HFSS)to further extend the EAB,achieving an EAB of 14.6 GHz and a RL_(min) of−59.0 dB.This research offers a viable inspiration to creating structures or materials with high-efficiency MA properties.展开更多
Photocatalytic decomposition of sugars is a promising way of providing H_(2),CO,and HCOOH as sus-tainable energy vectors.However,the production of C_(1) chemicals requires the cleavage of robust C−C bonds in sugars wi...Photocatalytic decomposition of sugars is a promising way of providing H_(2),CO,and HCOOH as sus-tainable energy vectors.However,the production of C_(1) chemicals requires the cleavage of robust C−C bonds in sugars with concurrent production of H_(2),which remains challenging.Here,the photo-catalytic activity for glucose decomposition to HCOOH,CO(C_(1) chemicals),and H_(2) on Cu/TiO_(2)was enhanced by nitrogen doping.Owing to nitrogen doping,atomically dispersed and stable Cu sites resistant to light irradiation are formed on Cu/TiO_(2).The electronic interaction between Cu and nitrogen ions originates valence band structure and defect levels composed of N 2p orbit,distinct from undoped Cu/TiO_(2).Therefore,the lifetime of charge carriers is prolonged,resulting in the pro-duction of C_(1) chemicals and H_(2) with productivities 1.7 and 2.1 folds that of Cu/TiO_(2).This work pro-vides a strategy to design coordinatively stable Cu ions for photocatalytic biomass conversion.展开更多
Studies showed that complexation of polyphenols with milk allergens reduced their immunogenic potential.However,the relationship between structures of polyphenols and their hypoallergenic effects on milk allergens in ...Studies showed that complexation of polyphenols with milk allergens reduced their immunogenic potential.However,the relationship between structures of polyphenols and their hypoallergenic effects on milk allergens in association with physiological and conformational changes of the complexes remain unclear.In this study,polyphenols from eight botanical sources were extracted to prepare non-covalent complexes withβ-lactoglobulin(β-LG),a major allergen in milk.The dominant phenolic compounds bound toβ-LG with a diminished allergenicity were identified to investigate their respective role on the structural and allergenic properties ofβ-LG.Extracts from Vaccinium fruits and black soybeans were found to have great inhibitory effects on the IgE-and IgG-binding abilities ofβ-LG.Among the fourteen structure-related phenolic compounds,flavonoids and tannins with larger MWs and multi-hydroxyl substituents,notably rutin,EGCG,and ellagitannins were more potent to elicit changes on the conformational structures ofβ-LG to decrease the allergenicity of complexedβ-LG.Correlation analysis further demonstrated that a destabilized secondary structure and protein depolymerization caused by polyphenol-binding were closely related to the allergenicity property of formed complexes.This study provides insights into the understanding of structure-allergenicity relationship ofβ-LG-polyphenol interactions and would benefit the development of polyphenol-fortified matrices with hypoallergenic potential.展开更多
Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter lea...Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter leads to the disagreement in the galaxy clustering amplitude, quantified by the parameter S8. Within the same model we described the Hubble tension. We described also the mechanism that transforms the gravitational collapse into an explosion—it concerns the dynamics of virtual fields that lead to dark energy. Our calculations concern the Type Ia supernovae and the core-collapse supernovae. We calculated the quantized masses of the progenitors of supernovae, emitted total energy during explosion, and we calculated how much of the released energy was transferred to neutrinos. Value of the speed of sound in the strongly interacting matter measured at the LHC confirms that presented here model is correct. Our calculations show that the Universe is cyclic.展开更多
E-learning platforms support education systems worldwide, transferring theoretical knowledge as well as soft skills. In the present study high-school pupils’, and adult students’ opinions were evaluated through a mo...E-learning platforms support education systems worldwide, transferring theoretical knowledge as well as soft skills. In the present study high-school pupils’, and adult students’ opinions were evaluated through a modern structured MOODLE interactive course, designed for the needs of the laboratory course “Automotive Systems”. The study concerns Greek secondary vocational education pupils aged 18 and vocational training adult students aged 20 to 50 years. The multistage, equal size simple random cluster sample was used as a sampling method. Pupils and adult students of each cluster completed structured 10-question questionnaires both before and after attending the course. A total of 120 questionnaires were collected. In general, our findings disclosed that the majority of pupils and adult students had significantly improved their knowledge and skills from using MOODLE. They reported strengthening conventional teaching, using the new MOODLE technology. The satisfaction indices improved quite, with the differences in their mean values being statistically significant.展开更多
基金supported in part by Award 2121063 from National Science Foundation(to YM)AG66986 from the National Institutes of Health(to MSW).
文摘γ-Secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface receptors.Mutations inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-Secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as well.However,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-secretase.In this review,we focus on recent studies of structural dynamic mechanisms ofγ-secretase.Different mechanisms,including the“Fit-Stay-Trim,”“Sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics simulations.While an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental findings.The approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-secretase.In addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is discussed.Finally,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations of theγ-secretase-substrate complexes.Comprehensive understanding of the functional mechanisms ofγ-secretase will greatly facilitate the rational design of effective drug molecules for treating familial Alzheimer’s disease and perhaps Alzheimer’s disease in general.
文摘Port structures constitute the main link in the maritime transport chain of coastal countries and therefore contribute to their economic development. But it should be noted that the installation of said works is not without consequences for the countries concerned. Benin, a country in the Gulf of Guinea, is no exception to this phenomenon because, due to its maritime history, it has a heritage of port structures. These structures, built on its coastline, cause a wide variety of environmental problems such as silting and erosion on either side of them. The general objective of this article is to contribute to the proper functionality of port facilities while minimizing environmental problems that may arise. It aims to provide managers with a tool allowing them to fully understand the state of their assets in order to rationalize maintenance actions. In order to achieve this objective, an assessment of the state of the structure, and then a structural diagnosis are necessary and recommendations can be established to restore the level of service of the latter. As a result, two examples were presented: the wharf of the Sèmè-Podji pipeline project and the maritime piles project of the Wasco de Gama bridge (control project), and recommendations adapted to this objective were established. The comparative analysis of the two examples, both maritime works, revealed an under-sizing at the level of the spans of the wharf bridge of the Sèmè-Podji pipeline project (spans of 7 m in length), while these spans vary on average by 45 m to 62 m for the Wasco da Gama bridge. Bringing the piles closer together at the Sèmè-Podji wharf reduces the energy of the current which promotes the accumulation of sediment. The structure no longer experiences a flow capable of setting in motion the sands accumulated since at least 2022. This element appears to be a fundamental characteristic explaining the erosion observed to the east of the structure.
基金Supported by the Foundation:This research project is jointly supported by Hebei Provincial Science and Technology Program(No.22375406D)The Earthquake Science and Technology Program of Hebei Province(No.DZ2023120500009,DZ2024120500001).
文摘NLLoc is a nonlinear search positioning method.In this study,we use simulated arrival time data to quantitatively evaluate the NLLoc method from three aspects:arrival time picking accuracy,station distribution,and velocity model.The results show that the NLLoc method exhibits high positioning accuracy and stability in terms of arrival time picking accuracy and station distribution;however,it is sensitive to the velocity model.The positioning accuracy is higher when the velocity model is smaller than the true velocity.We combined absolute and relative positioning methods.First,we use the NLLoc method for absolute positioning of seismic data and then the double difference positioning method for relative positioning to obtain a more accurate relocation result.Furthermore,we used the combined method to locate the earthquake sequence after collecting dense seismic array data on the Luanzhou M_(S)4.3 earthquake that occurred on April 16,2021,in Hebei Province.By fitting the fault plane with the relocated earthquake sequences,the results show that the strike and dip angles of the seismogenic fault of the Luanzhou M_(S)4.3 earthquake are 208.5°and 85.6°,respectively.This indicates a high-dip angle fault with North-North-East strike and North-West dip directions.Furthermore,we infer that the seismogenic fault of the Luanzhou M_(S)4.3 earthquake is the Lulong fault.
基金funding from the Hellenic Foundation for Research and Innovation(HFRI)under grant agreement No 3655.
文摘Proton exchange membrane fuel cells(PEMFCs)constitute a promising avenue for environmentally friendly power generation.However,the reliance on unsustainable platinum-based electrocatalysts used at the electrodes poses challenges to the commercial viability of PEMFCs.Non-platinum group metal(non-PGM)alternatives,like nitrogen-coordinated transition metals in atomic dispersion(M–N–C catalysts),show significant potential.This work presents a comparative study of two distinct sets of Fe–N–C materials,prepared by pyrolyzing hybrid composites of polyaniline(PANI)and iron(Ⅱ)chloride on a hard template.One set uses bipyridine(BPy)as an additional nitrogen source and iron ligand,offering an innovative approach.The findings reveal that the choice of pyrolysis temperature and atmosphere influences the catalyst properties.The use of ammonia in pyrolysis emerges as a crucial parameter for promoting atomic dispersion of iron,as well as increasing surface area and porosity.The optimal catalyst,prepared using BPy and ammonia,exhibits a half-wave potential of 0.834 V in 0.5 M H_(2)SO_(4)(catalyst loading of 0.6 mg cm^(-2)),a mass activity exceeding 3 A g^(-1)and high stability in acidic electrolyte,positioning it as a promising non-PGM structure in the field.
基金support from the Gansu Province Science and Technology Major Project(22ZD6GA008)Commissioner for Science,Technology Program of China Gansu Province(23CXA0013)+1 种基金National Natural Science Foundation of China(NSFC)(52061022)Jiayuguan City Science and Technology Major Project of China Gansu Province(22-02).
文摘The variations in the mechanical and magnetic properties of cold-rolled 20Mn23AlV non-magnetic structural steel after annealing at different temperatures were investigated.The microstructure and precipitation changes during annealing were studied by optical microscopy,scanning electron microscopy,and transmission electron microscopy.The results show that recrystallization completed after annealing at 620℃,resulting in grain sizes of approximately 800 nm and the best combination of strength and plasticity.The yield-to-tensile ratio of the non-magnetic structural steel after cold rolling continuously decreases from low to high temperatures after annealing,with the highest value being 0.89 and the lowest value being 0.43,indicating a wide range of yield-to-tensile ratio adjustment.The introduction of numerous dislocations during cold rolling provided favorable nucleation sites for precipitation,leading to abundant precipitation of the fine second-phase V(C,N).The phase composition of the samples remained unchanged as single-phase austenite after annealing,and the relative permeability values were calculated to be less than 1.002,meeting the requirements for non-magnetic steel in terms of magnetic properties.
文摘In this study,the casting process is used to fabricate modified polyvinyl alcohol(PVA),starch(S),and carboxymethyl cellulose(CMC)polymer blend films(PVA/S/CMC)loaded with various concentrations of irondoped carbon quantum dots(Fe-CQDs)and denoted as(PVA/S/CMC@Fe-CQDs).A one-step microwave strategy was employed as a facile method to prepare Fe-CQDs.Through a series of characterization techniques,fourier-transform infrared(FTIR)spectroscopy,x-ray diffraction(XRD)analysis,and scanning electron microscopy(SEM)have been used to show the successful integration of Fe-CQDs into the PVA/S/CMCmatrix.Loading the synthesized Fe-CQDs to the polymeric matrix significantly enhanced the mechanical properties of the films represented in the tensile strength,Young’s modulus,and hardness.However,the elongation decreased noticeably upon increasing the iron-doped carbon dots.The surface wettability was also studied by measuring the contact angle of the prepared films.The findings showed a noticeable elevation in these measurements by increasing the Fe-CQDs content,declaring the role of a hydrophobic character in these nanoparticles when introduced into a hydrophilic polymeric system.The dielectric characteristics of the reinforced polymer composite films were evaluated.These results revealed that the ac-conductivity of the investigated films was boosted with increasing Fe-CQDs’ratio and frequency.The PVA/S/CMC@Fe-CQDs films possess substantial potential for efficient energy storage applications.
基金financial support from the SERB-SURE under file number of SUR/2022/003129Jong Hyeok Park acknowledges the support of the National Research Foundation of Korea (NRF)funded by the Ministry of Science and ICT (RS-2023-00302697,RS-2023-00268523).
文摘Mo_(2)C is an excellent electrocatalyst for hydrogen evolution reaction(HER).However,Mo_(2)C is a poor electrocatalyst for oxygen evolution reaction(OER).Herein,two different elements,namely Co and Fe,are incorporated in Mo_(2)C that,therefore,has a finely tuned electronic structure,which is not achievable by incorporation of any one of the metals.Consequently,the resulting electrocatalyst Co_(0.8)Fe_(0.2)-Mo_(2)C-80 displayed excellent OER catalytic performance,which is evidenced by a low overpotential of 214.0(and 246.5)mV to attain a current density of 10(and 50)mA cm^(-2),an ultralow Tafel slope of 38.4 mV dec^(-1),and longterm stability in alkaline medium.Theoretical data demonstrates that Co_(0.8)Fe_(0.2)-Mo_(2)C-80 requires the lowest overpotential(1.00 V)for OER and Co centers to be the active sites.The ultrahigh catalytic performance of the electrocatalyst is attributed to the excellent intrinsic catalytic activity due to high Brunauer-Emmett-Teller specific surface area,large electrochemically active surface area,small Tafel slope,and low chargetransfer resistance.
基金financially supported by the National Natural Science Foundation of China(Nos.31971631,41977083,and 41671252)。
文摘Intensive management is known to markedly alter soil carbon(C)storage and turnover in Moso bamboo forests compared with extensive management.However,the effects of intensive management on soil respiration(RS)components remain unclear.This study aimed to evaluate the changes in different RScomponents(root,mycorrhizal,and free-living microorganism respiration)in Moso bamboo forests under extensive and intensive management practices.A1-year in-situ microcosm experiment was conducted to quantify the RScomponents in Moso bamboo forests under the two management practices using mesh screens of varying sizes.The results showed that the total RSand its components exhibited similar seasonal variability between the two management practices.Compared with extensive management,intensive management significantly increased cumulative respiration from mycorrhizal fungi by 36.73%,while decreased cumulative respiration from free-living soil microorganisms by 8.97%.Moreover,the abundance of arbuscular mycorrhizal fungi(AMF)increased by 43.38%,but bacterial and fungal abundances decreased by 21.65%and 33.30%,respectively,under intensive management.Both management practices significantly changed the bacterial community composition,which could be mainly explained by soil pH and available potassium.Mycorrhizal fungi and intensive management affected the interrelationships between bacterial members.Structural equation modeling indicated that intensive management changed the cumulative RSby elevating AMF abundance and lowering bacterial abundance.We concluded that intensive management reduced the microbial respiration-derived C loss,but increased mycorrhizal respiration-derived C loss.
基金financially supported by the National Natural Science Foundation of China(51972049,52073010,and 52373259)the Projects of the Science and Technology Department of Jilin Province(20230201132GX)the Projects of the Education Department of Jilin Province(JJKH20220123KJ)。
文摘The impedance matching of absorbers is a vital factor affecting their microwave absorption(MA)properties.In this work,we controllably synthesized Material of Institute Lavoisier 88C(MIL-88C)with varying aspect ratios(AR)as a precursor by regulating oil bath conditions,followed by one-step thermal decomposition to obtain carbon-coated iron-based composites.Modifying the precursor MIL-88C(Fe)preparation conditions,such as the molar ratio between metal ions and organic ligands(M/O),oil bath temperature,and oil bath time,influenced the phases,graphitization degree,and AR of the derivatives,enabling low filler loading,achieving well-matched impedance,and ensuring outstanding MA properties.The MOF-derivatives 2(MD_(2))/polyvinylidene Difluoride(PVDF),MD_(3)/PVDF,and MD4/PVDF absorbers all exhibited excellent MA properties with optimal filler loadings below 20 wt%and as low as 5 wt%.The MD_(2)/PVDF(5 wt%)achieved a maximum effective absorption bandwidth(EAB)of 5.52 GHz(1.90 mm).The MD_(3)/PVDF(10 wt%)possessed a minimum reflection loss(RL_(min))value of−67.4 at 12.56 GHz(2.13 mm).A symmetric gradient honeycomb structure(SGHS)was constructed utilizing the high-frequency structure simulator(HFSS)to further extend the EAB,achieving an EAB of 14.6 GHz and a RL_(min) of−59.0 dB.This research offers a viable inspiration to creating structures or materials with high-efficiency MA properties.
文摘Photocatalytic decomposition of sugars is a promising way of providing H_(2),CO,and HCOOH as sus-tainable energy vectors.However,the production of C_(1) chemicals requires the cleavage of robust C−C bonds in sugars with concurrent production of H_(2),which remains challenging.Here,the photo-catalytic activity for glucose decomposition to HCOOH,CO(C_(1) chemicals),and H_(2) on Cu/TiO_(2)was enhanced by nitrogen doping.Owing to nitrogen doping,atomically dispersed and stable Cu sites resistant to light irradiation are formed on Cu/TiO_(2).The electronic interaction between Cu and nitrogen ions originates valence band structure and defect levels composed of N 2p orbit,distinct from undoped Cu/TiO_(2).Therefore,the lifetime of charge carriers is prolonged,resulting in the pro-duction of C_(1) chemicals and H_(2) with productivities 1.7 and 2.1 folds that of Cu/TiO_(2).This work pro-vides a strategy to design coordinatively stable Cu ions for photocatalytic biomass conversion.
基金supported by the Zhejiang Provincial Natural Science Foundation of China(LGN22C200027 and LZ23C200001).
文摘Studies showed that complexation of polyphenols with milk allergens reduced their immunogenic potential.However,the relationship between structures of polyphenols and their hypoallergenic effects on milk allergens in association with physiological and conformational changes of the complexes remain unclear.In this study,polyphenols from eight botanical sources were extracted to prepare non-covalent complexes withβ-lactoglobulin(β-LG),a major allergen in milk.The dominant phenolic compounds bound toβ-LG with a diminished allergenicity were identified to investigate their respective role on the structural and allergenic properties ofβ-LG.Extracts from Vaccinium fruits and black soybeans were found to have great inhibitory effects on the IgE-and IgG-binding abilities ofβ-LG.Among the fourteen structure-related phenolic compounds,flavonoids and tannins with larger MWs and multi-hydroxyl substituents,notably rutin,EGCG,and ellagitannins were more potent to elicit changes on the conformational structures ofβ-LG to decrease the allergenicity of complexedβ-LG.Correlation analysis further demonstrated that a destabilized secondary structure and protein depolymerization caused by polyphenol-binding were closely related to the allergenicity property of formed complexes.This study provides insights into the understanding of structure-allergenicity relationship ofβ-LG-polyphenol interactions and would benefit the development of polyphenol-fortified matrices with hypoallergenic potential.
文摘Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter leads to the disagreement in the galaxy clustering amplitude, quantified by the parameter S8. Within the same model we described the Hubble tension. We described also the mechanism that transforms the gravitational collapse into an explosion—it concerns the dynamics of virtual fields that lead to dark energy. Our calculations concern the Type Ia supernovae and the core-collapse supernovae. We calculated the quantized masses of the progenitors of supernovae, emitted total energy during explosion, and we calculated how much of the released energy was transferred to neutrinos. Value of the speed of sound in the strongly interacting matter measured at the LHC confirms that presented here model is correct. Our calculations show that the Universe is cyclic.
文摘E-learning platforms support education systems worldwide, transferring theoretical knowledge as well as soft skills. In the present study high-school pupils’, and adult students’ opinions were evaluated through a modern structured MOODLE interactive course, designed for the needs of the laboratory course “Automotive Systems”. The study concerns Greek secondary vocational education pupils aged 18 and vocational training adult students aged 20 to 50 years. The multistage, equal size simple random cluster sample was used as a sampling method. Pupils and adult students of each cluster completed structured 10-question questionnaires both before and after attending the course. A total of 120 questionnaires were collected. In general, our findings disclosed that the majority of pupils and adult students had significantly improved their knowledge and skills from using MOODLE. They reported strengthening conventional teaching, using the new MOODLE technology. The satisfaction indices improved quite, with the differences in their mean values being statistically significant.
