Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoen...Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoenvironmental indicators on interbed development.With this aim in mind,we established an interbed classification scheme and quantified the development of different types of interbeds and their frequencies.We categorized the shale interbeds into three types based on interbed type:silt interbeds(SIs),shell fragment interbeds(SFIs),and shell skeleton interbeds(SSIs).The SIs,SFIs,and SSIs are respectively the products of extrabasinal low-density turbidity currents,intrabasinal debris flow,and intrabasinal low-density turbidity currents.We propose that variations in paleoenvironmental conditions primarily influenced the types of interbeds that developed but had minimal impact on the frequency of their development.Models depicting the interbed development within the 1st Submember of Dongyuemiao Member indicate that during the early Dongyuemiao depositional period,under conditions of relatively aridity,weak weathering,high terrigenous input,and strong hydrodynamic activity,SSIs were well developed.In the middle depositional period,as the climate gradually transitioned to more humid conditions,and the weathering intensity and amount of terrestrial input increased,the development of SIs and SFIs significantly increased.During the late depositional period,with a continuous decrease in terrestrial inputs and sedimentation rates,the development of SIs decreased while that of SSIs increased.展开更多
Camptotheca acuminata Decaisne is a tree unique to China, producing terpenoid indole alkaloid (TIA), camptothecin (CPT), and 10-hydroxycamptothecin (HCPT), which possesses strong anti-cancer bioactivity. The dynamics ...Camptotheca acuminata Decaisne is a tree unique to China, producing terpenoid indole alkaloid (TIA), camptothecin (CPT), and 10-hydroxycamptothecin (HCPT), which possesses strong anti-cancer bioactivity. The dynamics of HCPT and CPT during seed maturation, seed germination, postgerminative development and daily growth were measured by High Performance Liquid Chromatography (HPLC). This article provides some evidence for presenting the theory that each characteristic of HCPT and CPT accumulation is under developmental regulation and then attempt to elucidate the metabolic relationships between them. HCPT accumulates particularly in young tissues and organs and is relatively unstable, while the distribution of CPT is more ubiquitous and stable. Their different distribution properties suggest that HCPT and CPT are differentially regulated and play distinct roles:during development.展开更多
The development characteristics of Semiothisa cinerearia Bremer ＆ Grey was summarized, and we also put forward the control measures of well completing insect surveys to provide scientific basis for the control and ac...The development characteristics of Semiothisa cinerearia Bremer ＆ Grey was summarized, and we also put forward the control measures of well completing insect surveys to provide scientific basis for the control and actively carrying out comprehensive management to control the pests damage in the economic permissible level.展开更多
Shape is an important quality index of cold rolling strip. Up to now, many problems in the shape control domain have not been solved satisfactorily, and a review on the research progress in the shape control domain ca...Shape is an important quality index of cold rolling strip. Up to now, many problems in the shape control domain have not been solved satisfactorily, and a review on the research progress in the shape control domain can help to seek new breakthrough directions. In the past 10 years, researches and applications of shape control models, shape control means, shape detection technology, and shape con- trol system have achieved significant progress. In the aspect of shape control models, the researches in the past improve the accuracy, speed and robustness of the models. The intelligentization of shape control models should be strengthened in the future. In the aspect of the shape control means, the researches in the past focus on the roll opti- mization, mill type selection, process optimization, local strip shape control, edge drop control, and so on. In the future, more attention should be paid to the coordination control of both strip shape and other quality indexes, and the refinement of control objective should be strengthened. In the aspects of shape detection technology and shape control system, some new types of shape detection meters and shape control systems are developed and have successfully indus- trial applications. In the future, the standardization of shape detection technology and shape control system should be promoted to solve the problem of compatibility. In general,the four expected development trends of shape control for cold roiling strip in the future are intelligentization, coordi- nation, refinement, and standardization. The proposed research provides new breakthrough directions for improv- ing shape quality.展开更多
Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,w...Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,which causes worse local agricultural conditions accordingly.Many physical properties of arsenic sandstone is complementary with that of sand,arsenic sandstone is therefore supposed to be blended to enhance water productivity and arability of sandy land.Container experiments are carried out to study the enhancement of water holding capacity of the mixture,the blending ratio of arsenic sandstone and sand,and the proper size of the arsenic sandstone particles,respectively.The results of the experiments show that particle size of 4 cm with a ratio of 1∶2 between arsenic sandstone and sand are the proper parameters on blending.Both water content and fertility increase after blending.Water use efficiency in the mixture is 2.7 times higher than that in sand by the water release curves from experiments.Therefore,a new sand control and development model,including arsenic sandstone blending with sand,efficient water irrigation management and reasonable farming system,is put forward to control and develop sandy land so that water-saving agriculture could be developed.Demonstration of potato planting about 153.1 ha in area in the Mu Us Sandy Land in China indicates that water consumption is 3018 m3/ha in the whole growth period.It means that about 61%of irrigation water can be saved compared with water use in coarse sand without treatment.Recycle economic mode and positive feedback of sand resource-crop planting-soil resource are constructed,which changes sand into arable soil and make it possible to develop water-saving agriculture on it.The proposed model will be helpful for soil-water resources utilization and management in the Mu Us Sandy Land.展开更多
In the field of industrial process control,a fast-development platform for programmable logic controller(PLC)systems is designed in order to solve two main problems of rapid development of PLC control system and progr...In the field of industrial process control,a fast-development platform for programmable logic controller(PLC)systems is designed in order to solve two main problems of rapid development of PLC control system and programmability of controlling software.In the aspect of design,the platform is composed of hardware controlling and software monitoring and is taking industrial computer as the core.Under the Windows environment,the platform establishes the control instruction set,develops the configuration function and visual programming function of the monitoring software and it integrates PLC controller based on Visual Basic software.In order to achieve the function of data monitoring,it has realized the serial communication between computer and PLC by using RS-485 and RS-232 serial ports line communication.The platform designs the intelligent instruction scheduling strategy by studying the encoding and decoding rules of the communication instruction set.It proposes a method for rapidly developing control programs by adopting the expert control mode,which enables clients to develop and modify programs conveniently by importing instructions in a non-coded manner.After experimental testing,the platform is proved successful achieving both the rapid development of PLC control system and the rapid modification of monitoring software.展开更多
Natural fractures are critical for shale oil and gas enrichment and development. Due to the extremely high heterogeneity of shale, the factors controlling the formation of internal fractures, especially horizontal fra...Natural fractures are critical for shale oil and gas enrichment and development. Due to the extremely high heterogeneity of shale, the factors controlling the formation of internal fractures, especially horizontal fractures, remain controversial. In this study, we integrate thin section analysis and microcomputed tomography(CT) data from several lacustrine shale samples from the third member(Es3) of the Shahejie Formation, Qikou Sag, Bohai Bay Basin, to assess the fractures in detail. The goal is to reveal the development characteristics, controlling factors, and geological significance for evaluating sweet spots in a shale oil play. The fractures in the Es3contain high-angle structural and horizontal bed-parallel fractures that are mostly shear and extensional. Various factors influence fracture development,including lithofacies, mineral composition, organic matter content, and the number of laminae. Structural fractures occur predominantly in siltstone, whereas bed-parallel fractures are abundant in laminated shale and layered mudstone. A higher quartz content results in higher shale brittleness, causing fractures, whereas the transformation between clay minerals contributes to the development of bedparallel fractures. Excess pore pressure due to hydrocarbon generation and expulsion during thermal advance can cause the formation of bed-parallel fractures. The density of the bed-parallel and structural fractures increases with the lamina density, and the bed-parallel fractures are more sensitive to the number of laminae. The fractures are critical storage spaces and flow conduits and are indicative of sweet spots. The laminated shale in the Es3with a high organic matter content contains natural fractures and is an organic-rich, liquid-rich, self-sourced shale play. Conversely, the siltstone, massive mudstone, and argillaceous carbonate lithofacies contain lower amounts of organic matter and do not have bed-parallel fractures. However, good reservoirs can form in these areas when structural fractures are present and the source, and storage spaces are separated.展开更多
Projections for 20 years of economic growth and change in the structure of the Thai economy were made for 180 sectors using a computable general equilibrium(CGE) model to compare the following four scenarios:(1) stand...Projections for 20 years of economic growth and change in the structure of the Thai economy were made for 180 sectors using a computable general equilibrium(CGE) model to compare the following four scenarios:(1) standard growth with infinite supply of factors,(2) finite land supply,(3) fixed use of agricultural chemicals,and(4) combined finite land supply with fixed use of agricultural chemicals.The computable projections suggest that the economic cost of hypothetical environmental control in agriculture is small and further weakened by urbanization.The computed structural development points to efficiency improvements specific to sectors to return the economy to balanced growth.展开更多
Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitness. Glucose-6-phosphate/phosphate translocator(GPT) transports glucose-6-phosp...Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitness. Glucose-6-phosphate/phosphate translocator(GPT) transports glucose-6-phosphate, a key precursor of starch and/or fatty acid biosynthesis, into plastids. Here, we report the functional characterization of Os GPT1 in the rice anther development and pollen fertility. Pollen grains from homozygous osgpt1 mutant plants fail to accumulate starch granules, resulting in pollen sterility. Genetic analyses reveal a sporophytic effect for this mutation. Os GPT1 is highly expressed in the tapetal layer of rice anther. Degeneration of the tapetum, an important process to provide cellular contents to support pollen development, is impeded in osgpt1 plants. In addition, defective intine and exine are observed in the pollen from osgpt1 plants. Expression levels of multiple genes that are important to tapetum degeneration or pollen wall formation are significantly decreased in osgpt1 anthers. Previously, we reported that At GPT1 plays a gametic function in the accumulation of lipid bodies in Arabidopsis pollen. This report highlights a sporophytic role of Os GPT1 in the tapetum degeneration and pollen development. The divergent functions of Os GPT1 and At GPT1 in pollen development might be a result of their independent evolution after monocots and dicots diverged.展开更多
<strong>Context:</strong> Substandard and falsified medicines are circulating in low-income countries mostly without any control. We availed a simple and not expensive UV-Vis spectroscopic method to evalua...<strong>Context:</strong> Substandard and falsified medicines are circulating in low-income countries mostly without any control. We availed a simple and not expensive UV-Vis spectroscopic method to evaluate the quality of tramadol in Kisangani before and during the Covid-19 period. <strong>Methods:</strong> For the analytical quantitative method, an experimental design was applied to set up the optimal levels of the selected factors, namely, pH of dissolution medium, type of cuvette, and wavelength. Taking into account the capsule pharmaceutical formulation within 80 - 120 μg·mL<sup>-1</sup> concentration range, we analyzed 89 tramadol samples from pharmacies and hospitals of the six Kisangani municipalities. <strong>Results:</strong> pH showed a significant effect on absorbance, whereas quartz cuvette and wavelength did not. A typical 100 μg·mL<sup>-1</sup> tramadol solution gave an absorbance of 0.64 at 272 nm. Validation highlighted a matrix effect observed with a 6% bias. A correction factor of 0.9372 allowed to improve the accuracy profile, which were then totally included within the 10% acceptance limits. Quality control revealed that 25 samples out of 89 were not compliant in terms of manufacturing license, registration status in DRC and content as well. <strong>Conclusion:</strong> This study showed that the strengthening of analytical strategy in Kisangani is a need.展开更多
Based on drilling, logging, test production and dynamic monitoring data, the control effects of low-amplitude structure on hydrocarbon accumulation and development performance of ultra-low permeability reservoirs were...Based on drilling, logging, test production and dynamic monitoring data, the control effects of low-amplitude structure on hydrocarbon accumulation and development performance of ultra-low permeability reservoirs were discussed by using the methods of dense well pattern, multi-factor geological modeling, macro and micro analysis and static and dynamic analysis. The results show that the low-amplitude structure always had a significant control and influence on the distribution and accumulation of original hydrocarbon and water and the evolution trend of water flooding performance in ultra-low permeability reservoirs, and it was not only the direction of oil and gas migration, but also a favorable place for relative accumulation of oil and gas. The controlling effect of low-amplitude structure on ultra-low permeability reservoir mainly depended on its tectonic amplitude and scale;the larger the tectonic amplitude and scale, and the higher the tectonic position of the low amplitude structure, the better the reservoir characteristic parameters, oil and gas enrichment degree and development effect, and the larger the spatial scope it controlled and influenced;water cut and oil well output always fluctuated orderly with the height of the low-amplitude structure;the dynamic response of waterflooding was closely related to the relative structural position of the injection and production wells;the injected water always advanced to the low-lying area of the structure first and then moved up to the high-lying area of the structure gradually;with the continuous expansion of the flooded area, part of the oil and gas in the low-lying part of the structure was forced to be distributed to the high part of the structure, resulting in a new oil and gas enrichment, so that the dynamic reserves of oil wells in the high part increased, and the production capacity remained stable.展开更多
How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated i...How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal genetic diseases that exhibit craniofacial bone defects. The GNAS gene encodes Gαs that transduces GPCR signaling. GNAS activation or loss-of-function mutations in humans cause fibrous dysplasia(FD) or progressive osseous heteroplasia(POH) that shows craniofacial hyperostosis or craniosynostosis, respectively. We find here that, while Hh ligand-dependent Hh signaling is essential for endochondral ossification, it is dispensable for intramembranous ossification, where Gαsregulates Hh signaling in a ligand-independent manner. We further show that Gαscontrols intramembranous ossification by regulating both Hh and Wnt/β-catenin signaling. In addition, Gαsactivation in the developing cranial bone leads to reduced ossification but increased cartilage presence due to reduced cartilage dissolution, not cell fate switch. Small molecule inhibitors of Hh and Wnt signaling can effectively ameliorate cranial bone phenotypes in mice caused by loss or gain of Gnas function mutations, respectively. Our work shows that studies of genetic diseases provide invaluable insights in both pathological bone defects and normal bone development, understanding both leads to better diagnosis and therapeutic treatment of bone diseases.展开更多
As one of the most effective vehicles for ocean development and exploration,underwater gliding robots(UGRs)have the unique characteristics of low energy consumption and strong endurance.Moreover,by borrowing the motio...As one of the most effective vehicles for ocean development and exploration,underwater gliding robots(UGRs)have the unique characteristics of low energy consumption and strong endurance.Moreover,by borrowing the motion principles of current underwater robots,a variety of novel UGRs have emerged with improving their maneuverability,concealment,and environmental friendliness,which significantly broadens the ocean applications.In this paper,we provide a comprehensive review of underwater gliding robots,including prototype design and their key technologies.From the perspective of motion characteristics,we categorize the underwater gliding robots in terms of traditional underwater gliders(UGs),hybrid-driven UGs,bio-inspired UGs,thermal UGs,and others.Correspondingly,their buoyancy driven system,dynamic and energy model,and motion control are concluded with detailed analysis.Finally,we have discussed the current critical issues and future development.This review offers valuable insight into the development of next-generation underwater robots well-suited for various oceanic applications,and aims to gain more attention of researchers and engineers to this growing field.展开更多
Affecting about 241.4 million people worldwide,Schistosoma(S.)mansoni,the main etiological agent of intestinal schistosomiasis,is one of the most prevalent diseases in the world remaining a public health issue,especia...Affecting about 241.4 million people worldwide,Schistosoma(S.)mansoni,the main etiological agent of intestinal schistosomiasis,is one of the most prevalent diseases in the world remaining a public health issue,especially in developing countries in South America,Africa and the Caribbean.In Brazil,more than 30 million people are at risk of infection,and nearly 1.5 million are infected by S.mansoni[1].Although the implemented control measures proved to be efficient and contributed to a decrease in morbidity and mortality associated with S.mansoni infections,they led to a new epidemiological scenario characterized by low-intensity infections and areas with low prevalence,presenting a new challenge towards the elimination and control of schistosomiasis[2].展开更多
On the basis of classification of geographical properties a rolling develop-ment goal programming model is formulated in correspondence with the ecopatterngroup in Four-Lake Area. In this model, the control of schisto...On the basis of classification of geographical properties a rolling develop-ment goal programming model is formulated in correspondence with the ecopatterngroup in Four-Lake Area. In this model, the control of schistosomiasis and strengthen-ing of the drainage-storage function are both regarded as ecological measures duringthe process of multi-year(r_0) ecological economic rolling development to make theecoagricultural system in this area ioto a stably operating, ordered, and good cyclicsystem under the support of some controllable factors.展开更多
Software has been developed for digital control of WDW series testing machine and the measurement of fracture toughness by modularized design. Development of the software makes use of multi-thread and serial communica...Software has been developed for digital control of WDW series testing machine and the measurement of fracture toughness by modularized design. Development of the software makes use of multi-thread and serial communication techniques, which can accurately control the testing machine and measure the fracture toughness in real-time. Three-point bending specimens were used in the measurement. The software operates stably and reliably, expanding the function of WDW series testing machine.展开更多
The development of gas condensate reservoirs with a large gas cap,thin oil rim,strong bottom water,and natural barriers faces numerous challenges,including reservoir heterogeneity,coning effects,phase changes,and mult...The development of gas condensate reservoirs with a large gas cap,thin oil rim,strong bottom water,and natural barriers faces numerous challenges,including reservoir heterogeneity,coning effects,phase changes,and multiphase flow dynamics.The influx of gas and water may lead to a low recovery of the oil rim,while reservoir heterogeneity and natural barriers further exacerbate the uneven distribution of reservoir fluid,complicating development strategies.This paper aims to investigate innovative and effective development strategies for this type of reservoir.A detailed,proportionally scaled numerical simulation is performed based on the experimental results of an artificial sand-filled model,providing novel insights into the dynamic behavior of these reservoirs.By understanding the phase behavior and fluid flow characteristics of the reservoir,the study simulates various strategies for the rational and efficient development of the gas condensate reservoir.These strategies include well patterns and completions,the decision to develop the oil rim or gas cap,depletion rates,the bottom water control,and gas injection.The results show that horizontal wells or highly deviated wells are more suitable for the development of the oil rim,as they provide larger control ranges.The presence of strong bottom water is advantageous for displacement energy supply and pressure maintenance,but it intensifies water coning effects,leading to an earlier breakthrough and a sharp production decline.Therefore,it is preferable to apply highly deviated wells at the oil-gas contact,developing the oil rim at lower rates and smaller pressure gradients,followed by developing the gas cap.This approach can reduce water coning effects and improve recovery,with oil and gas recovery reaching 24.4%and 67.95%,respectively,which is an increase of 16.74%and 17.84%compared to direct depletion development of the gas cap.Due to the strong water bottom,continuous gas injection at the top of the reservoir becomes challenging.This study introduces gas assisted gravity drainage with water control technology,a novel and highly effective approach that addresses the impact of bottom water coning effects on the oil and gas zones and overcomes the limitations of gas flooding in reservoirs with strong bottom water.This method can significantly improve oil and gas recovery,achieving recovery of 39.74%and 84.50%,respectively.Compared to the conventional depletion strategy of sequential oil rim and gas cap development,this method achieves additional improvements of 15.33%and 16.55%in oil and gas recovery,respectively.展开更多
GABAergic neurons are the major inhibitory interneurons that powerfully control the function of spinal neuronal networks.In recent years,tremendous progresses have been made in understanding the transcriptional contro...GABAergic neurons are the major inhibitory interneurons that powerfully control the function of spinal neuronal networks.In recent years,tremendous progresses have been made in understanding the transcriptional control of GABAergic neuron development in the dorsal spinal cord.New experimental approaches provide a relatively high throughput way to study the molecular regulation of subgroup fate determination.Our understanding of the molecular mechanisms on GABAergic neuron development in the dorsal spinal cord is rapidly expanding.Recent studies have defined several transcription factors that play essential roles in GABAergic neuron development in the spinal dorsal horn.Here,we review results of very recent analyses of the mechanisms that specify the GABAergic neuron development in the dorsal spinal cord,especially the progresses in the homeodomain(HD) and basic-helix-loop-helix(bHLH) containing transcription factors.展开更多
This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e ...This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e developed within the system. The prospects and challenges towards implementati on of the system are also discussed.展开更多
Based on the research on domestic and international automatic technical development in fossil power plant,the paper analyses the recent situation of the coordinate control system between turbine and boiler of domestic...Based on the research on domestic and international automatic technical development in fossil power plant,the paper analyses the recent situation of the coordinate control system between turbine and boiler of domestic fossil Power Plant,provides the development thought of coordinate control system between turbine and boiler,and describes the application prospect in control system of fossil power plant combining with the application experience.展开更多
基金sponsored by the National Natural Science Foundation of China,China(No.42272171)National Science and Technology Major Project of China,China(No.2017ZX05036).
文摘Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoenvironmental indicators on interbed development.With this aim in mind,we established an interbed classification scheme and quantified the development of different types of interbeds and their frequencies.We categorized the shale interbeds into three types based on interbed type:silt interbeds(SIs),shell fragment interbeds(SFIs),and shell skeleton interbeds(SSIs).The SIs,SFIs,and SSIs are respectively the products of extrabasinal low-density turbidity currents,intrabasinal debris flow,and intrabasinal low-density turbidity currents.We propose that variations in paleoenvironmental conditions primarily influenced the types of interbeds that developed but had minimal impact on the frequency of their development.Models depicting the interbed development within the 1st Submember of Dongyuemiao Member indicate that during the early Dongyuemiao depositional period,under conditions of relatively aridity,weak weathering,high terrigenous input,and strong hydrodynamic activity,SSIs were well developed.In the middle depositional period,as the climate gradually transitioned to more humid conditions,and the weathering intensity and amount of terrestrial input increased,the development of SIs and SFIs significantly increased.During the late depositional period,with a continuous decrease in terrestrial inputs and sedimentation rates,the development of SIs decreased while that of SSIs increased.
文摘Camptotheca acuminata Decaisne is a tree unique to China, producing terpenoid indole alkaloid (TIA), camptothecin (CPT), and 10-hydroxycamptothecin (HCPT), which possesses strong anti-cancer bioactivity. The dynamics of HCPT and CPT during seed maturation, seed germination, postgerminative development and daily growth were measured by High Performance Liquid Chromatography (HPLC). This article provides some evidence for presenting the theory that each characteristic of HCPT and CPT accumulation is under developmental regulation and then attempt to elucidate the metabolic relationships between them. HCPT accumulates particularly in young tissues and organs and is relatively unstable, while the distribution of CPT is more ubiquitous and stable. Their different distribution properties suggest that HCPT and CPT are differentially regulated and play distinct roles:during development.
文摘The development characteristics of Semiothisa cinerearia Bremer ＆ Grey was summarized, and we also put forward the control measures of well completing insect surveys to provide scientific basis for the control and actively carrying out comprehensive management to control the pests damage in the economic permissible level.
基金Supported by National Key Technology Support Program of China (Grant No. 2011BAF15B00)Hebei Provincial Natural Science Foundation of China (Grant No. E2016203482)+1 种基金Hebei Provincial Science and Technology Research Foundation of China (Grant No. ZD2014034)Youth Independent Research Program of Yanshan University of China (Grant No. 14LGA003)
文摘Shape is an important quality index of cold rolling strip. Up to now, many problems in the shape control domain have not been solved satisfactorily, and a review on the research progress in the shape control domain can help to seek new breakthrough directions. In the past 10 years, researches and applications of shape control models, shape control means, shape detection technology, and shape con- trol system have achieved significant progress. In the aspect of shape control models, the researches in the past improve the accuracy, speed and robustness of the models. The intelligentization of shape control models should be strengthened in the future. In the aspect of the shape control means, the researches in the past focus on the roll opti- mization, mill type selection, process optimization, local strip shape control, edge drop control, and so on. In the future, more attention should be paid to the coordination control of both strip shape and other quality indexes, and the refinement of control objective should be strengthened. In the aspects of shape detection technology and shape control system, some new types of shape detection meters and shape control systems are developed and have successfully indus- trial applications. In the future, the standardization of shape detection technology and shape control system should be promoted to solve the problem of compatibility. In general,the four expected development trends of shape control for cold roiling strip in the future are intelligentization, coordi- nation, refinement, and standardization. The proposed research provides new breakthrough directions for improv- ing shape quality.
基金Under the auspices of National Natural Science Foundation of China(No.51079120)Education Department Research Program of Shaanxi Province(No.12JK0481)Water Conservancy Science and Technology Plan of Shaanxi Province(No.2012-07)
文摘Serious desertification caused by human activity and climate change,in addition to water loss and soil erosion related to arsenic sandstone in the Mu Us Sandy Land,lead to severe scarcity of soil and water resources,which causes worse local agricultural conditions accordingly.Many physical properties of arsenic sandstone is complementary with that of sand,arsenic sandstone is therefore supposed to be blended to enhance water productivity and arability of sandy land.Container experiments are carried out to study the enhancement of water holding capacity of the mixture,the blending ratio of arsenic sandstone and sand,and the proper size of the arsenic sandstone particles,respectively.The results of the experiments show that particle size of 4 cm with a ratio of 1∶2 between arsenic sandstone and sand are the proper parameters on blending.Both water content and fertility increase after blending.Water use efficiency in the mixture is 2.7 times higher than that in sand by the water release curves from experiments.Therefore,a new sand control and development model,including arsenic sandstone blending with sand,efficient water irrigation management and reasonable farming system,is put forward to control and develop sandy land so that water-saving agriculture could be developed.Demonstration of potato planting about 153.1 ha in area in the Mu Us Sandy Land in China indicates that water consumption is 3018 m3/ha in the whole growth period.It means that about 61%of irrigation water can be saved compared with water use in coarse sand without treatment.Recycle economic mode and positive feedback of sand resource-crop planting-soil resource are constructed,which changes sand into arable soil and make it possible to develop water-saving agriculture on it.The proposed model will be helpful for soil-water resources utilization and management in the Mu Us Sandy Land.
基金Supported by the International S&T Cooperation Program of China(No.2014DFR70280)Key Research and Development Project of Shanxi Province(No.201903D321012)+1 种基金Key Research and Development Project of Shanxi Province(No.201903D121023)Patent Promotion and Implementation Funding Research Project of Shanxi Province(No.20210521).
文摘In the field of industrial process control,a fast-development platform for programmable logic controller(PLC)systems is designed in order to solve two main problems of rapid development of PLC control system and programmability of controlling software.In the aspect of design,the platform is composed of hardware controlling and software monitoring and is taking industrial computer as the core.Under the Windows environment,the platform establishes the control instruction set,develops the configuration function and visual programming function of the monitoring software and it integrates PLC controller based on Visual Basic software.In order to achieve the function of data monitoring,it has realized the serial communication between computer and PLC by using RS-485 and RS-232 serial ports line communication.The platform designs the intelligent instruction scheduling strategy by studying the encoding and decoding rules of the communication instruction set.It proposes a method for rapidly developing control programs by adopting the expert control mode,which enables clients to develop and modify programs conveniently by importing instructions in a non-coded manner.After experimental testing,the platform is proved successful achieving both the rapid development of PLC control system and the rapid modification of monitoring software.
基金financially supported by the CNPC Prospective Basic Science and Technology Special Project(2023ZZ08)the Science and Technology Cooperation Project of the CNPC-SWPU Innovation Alliance(2020CX050103)。
文摘Natural fractures are critical for shale oil and gas enrichment and development. Due to the extremely high heterogeneity of shale, the factors controlling the formation of internal fractures, especially horizontal fractures, remain controversial. In this study, we integrate thin section analysis and microcomputed tomography(CT) data from several lacustrine shale samples from the third member(Es3) of the Shahejie Formation, Qikou Sag, Bohai Bay Basin, to assess the fractures in detail. The goal is to reveal the development characteristics, controlling factors, and geological significance for evaluating sweet spots in a shale oil play. The fractures in the Es3contain high-angle structural and horizontal bed-parallel fractures that are mostly shear and extensional. Various factors influence fracture development,including lithofacies, mineral composition, organic matter content, and the number of laminae. Structural fractures occur predominantly in siltstone, whereas bed-parallel fractures are abundant in laminated shale and layered mudstone. A higher quartz content results in higher shale brittleness, causing fractures, whereas the transformation between clay minerals contributes to the development of bedparallel fractures. Excess pore pressure due to hydrocarbon generation and expulsion during thermal advance can cause the formation of bed-parallel fractures. The density of the bed-parallel and structural fractures increases with the lamina density, and the bed-parallel fractures are more sensitive to the number of laminae. The fractures are critical storage spaces and flow conduits and are indicative of sweet spots. The laminated shale in the Es3with a high organic matter content contains natural fractures and is an organic-rich, liquid-rich, self-sourced shale play. Conversely, the siltstone, massive mudstone, and argillaceous carbonate lithofacies contain lower amounts of organic matter and do not have bed-parallel fractures. However, good reservoirs can form in these areas when structural fractures are present and the source, and storage spaces are separated.
基金supported by School of Social and Environmental Development,National Institute of Development Administration,Bangkok,Thailand[grant date:8 August 2012]
文摘Projections for 20 years of economic growth and change in the structure of the Thai economy were made for 180 sectors using a computable general equilibrium(CGE) model to compare the following four scenarios:(1) standard growth with infinite supply of factors,(2) finite land supply,(3) fixed use of agricultural chemicals,and(4) combined finite land supply with fixed use of agricultural chemicals.The computable projections suggest that the economic cost of hypothetical environmental control in agriculture is small and further weakened by urbanization.The computed structural development points to efficiency improvements specific to sectors to return the economy to balanced growth.
基金supported by the grants from National Natural Science Foundation of China (31922005)Zhejiang Provincial Natural Science Foundation of China (LR18C020001)+2 种基金Zhejiang University K.P.Chao’s High Technology Development Foundation (2018RC016)the Young Elite Scientist Sponsorship Program by CAST (2018QNRC001)111 Project (B14027) to J.X。
文摘Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitness. Glucose-6-phosphate/phosphate translocator(GPT) transports glucose-6-phosphate, a key precursor of starch and/or fatty acid biosynthesis, into plastids. Here, we report the functional characterization of Os GPT1 in the rice anther development and pollen fertility. Pollen grains from homozygous osgpt1 mutant plants fail to accumulate starch granules, resulting in pollen sterility. Genetic analyses reveal a sporophytic effect for this mutation. Os GPT1 is highly expressed in the tapetal layer of rice anther. Degeneration of the tapetum, an important process to provide cellular contents to support pollen development, is impeded in osgpt1 plants. In addition, defective intine and exine are observed in the pollen from osgpt1 plants. Expression levels of multiple genes that are important to tapetum degeneration or pollen wall formation are significantly decreased in osgpt1 anthers. Previously, we reported that At GPT1 plays a gametic function in the accumulation of lipid bodies in Arabidopsis pollen. This report highlights a sporophytic role of Os GPT1 in the tapetum degeneration and pollen development. The divergent functions of Os GPT1 and At GPT1 in pollen development might be a result of their independent evolution after monocots and dicots diverged.
文摘<strong>Context:</strong> Substandard and falsified medicines are circulating in low-income countries mostly without any control. We availed a simple and not expensive UV-Vis spectroscopic method to evaluate the quality of tramadol in Kisangani before and during the Covid-19 period. <strong>Methods:</strong> For the analytical quantitative method, an experimental design was applied to set up the optimal levels of the selected factors, namely, pH of dissolution medium, type of cuvette, and wavelength. Taking into account the capsule pharmaceutical formulation within 80 - 120 μg·mL<sup>-1</sup> concentration range, we analyzed 89 tramadol samples from pharmacies and hospitals of the six Kisangani municipalities. <strong>Results:</strong> pH showed a significant effect on absorbance, whereas quartz cuvette and wavelength did not. A typical 100 μg·mL<sup>-1</sup> tramadol solution gave an absorbance of 0.64 at 272 nm. Validation highlighted a matrix effect observed with a 6% bias. A correction factor of 0.9372 allowed to improve the accuracy profile, which were then totally included within the 10% acceptance limits. Quality control revealed that 25 samples out of 89 were not compliant in terms of manufacturing license, registration status in DRC and content as well. <strong>Conclusion:</strong> This study showed that the strengthening of analytical strategy in Kisangani is a need.
基金Supported by Open Fund(PLC20190203)of State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation(Chengdu University of Technology)the Natural Science Foundation of Shaanxi Province,China(2006Z07,2010JM5003)Youth Science and Technology Innovation Fund Project of Xi’an Petroleum University(2012BS010)
文摘Based on drilling, logging, test production and dynamic monitoring data, the control effects of low-amplitude structure on hydrocarbon accumulation and development performance of ultra-low permeability reservoirs were discussed by using the methods of dense well pattern, multi-factor geological modeling, macro and micro analysis and static and dynamic analysis. The results show that the low-amplitude structure always had a significant control and influence on the distribution and accumulation of original hydrocarbon and water and the evolution trend of water flooding performance in ultra-low permeability reservoirs, and it was not only the direction of oil and gas migration, but also a favorable place for relative accumulation of oil and gas. The controlling effect of low-amplitude structure on ultra-low permeability reservoir mainly depended on its tectonic amplitude and scale;the larger the tectonic amplitude and scale, and the higher the tectonic position of the low amplitude structure, the better the reservoir characteristic parameters, oil and gas enrichment degree and development effect, and the larger the spatial scope it controlled and influenced;water cut and oil well output always fluctuated orderly with the height of the low-amplitude structure;the dynamic response of waterflooding was closely related to the relative structural position of the injection and production wells;the injected water always advanced to the low-lying area of the structure first and then moved up to the high-lying area of the structure gradually;with the continuous expansion of the flooded area, part of the oil and gas in the low-lying part of the structure was forced to be distributed to the high part of the structure, resulting in a new oil and gas enrichment, so that the dynamic reserves of oil wells in the high part increased, and the production capacity remained stable.
基金supported by the NIH grants R01DE025866 from NIDCRR01AR070877 from NIAMSsupported by the 111 Project, MOE (B14038), China
文摘How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal genetic diseases that exhibit craniofacial bone defects. The GNAS gene encodes Gαs that transduces GPCR signaling. GNAS activation or loss-of-function mutations in humans cause fibrous dysplasia(FD) or progressive osseous heteroplasia(POH) that shows craniofacial hyperostosis or craniosynostosis, respectively. We find here that, while Hh ligand-dependent Hh signaling is essential for endochondral ossification, it is dispensable for intramembranous ossification, where Gαsregulates Hh signaling in a ligand-independent manner. We further show that Gαscontrols intramembranous ossification by regulating both Hh and Wnt/β-catenin signaling. In addition, Gαsactivation in the developing cranial bone leads to reduced ossification but increased cartilage presence due to reduced cartilage dissolution, not cell fate switch. Small molecule inhibitors of Hh and Wnt signaling can effectively ameliorate cranial bone phenotypes in mice caused by loss or gain of Gnas function mutations, respectively. Our work shows that studies of genetic diseases provide invaluable insights in both pathological bone defects and normal bone development, understanding both leads to better diagnosis and therapeutic treatment of bone diseases.
基金the National Natural Science Foundation of China(61725305,62033013,U1909206,T2121002)。
文摘As one of the most effective vehicles for ocean development and exploration,underwater gliding robots(UGRs)have the unique characteristics of low energy consumption and strong endurance.Moreover,by borrowing the motion principles of current underwater robots,a variety of novel UGRs have emerged with improving their maneuverability,concealment,and environmental friendliness,which significantly broadens the ocean applications.In this paper,we provide a comprehensive review of underwater gliding robots,including prototype design and their key technologies.From the perspective of motion characteristics,we categorize the underwater gliding robots in terms of traditional underwater gliders(UGs),hybrid-driven UGs,bio-inspired UGs,thermal UGs,and others.Correspondingly,their buoyancy driven system,dynamic and energy model,and motion control are concluded with detailed analysis.Finally,we have discussed the current critical issues and future development.This review offers valuable insight into the development of next-generation underwater robots well-suited for various oceanic applications,and aims to gain more attention of researchers and engineers to this growing field.
基金financed by the National Council for Scientific and Technological Development(CNPq)-Universal Number 18/2021:405731/2021-3.
文摘Affecting about 241.4 million people worldwide,Schistosoma(S.)mansoni,the main etiological agent of intestinal schistosomiasis,is one of the most prevalent diseases in the world remaining a public health issue,especially in developing countries in South America,Africa and the Caribbean.In Brazil,more than 30 million people are at risk of infection,and nearly 1.5 million are infected by S.mansoni[1].Although the implemented control measures proved to be efficient and contributed to a decrease in morbidity and mortality associated with S.mansoni infections,they led to a new epidemiological scenario characterized by low-intensity infections and areas with low prevalence,presenting a new challenge towards the elimination and control of schistosomiasis[2].
基金The work is supported by National Natural Science Foundation of China,Open Lab.of Management,Decision & Information System,Academia Sinice,and Young Scientist Lab.of Mathematical Physics,Wuhan.
文摘On the basis of classification of geographical properties a rolling develop-ment goal programming model is formulated in correspondence with the ecopatterngroup in Four-Lake Area. In this model, the control of schistosomiasis and strengthen-ing of the drainage-storage function are both regarded as ecological measures duringthe process of multi-year(r_0) ecological economic rolling development to make theecoagricultural system in this area ioto a stably operating, ordered, and good cyclicsystem under the support of some controllable factors.
文摘Software has been developed for digital control of WDW series testing machine and the measurement of fracture toughness by modularized design. Development of the software makes use of multi-thread and serial communication techniques, which can accurately control the testing machine and measure the fracture toughness in real-time. Three-point bending specimens were used in the measurement. The software operates stably and reliably, expanding the function of WDW series testing machine.
基金the support from the National Natural Science Foundation of China(NSFC Grant No.:52004032)。
文摘The development of gas condensate reservoirs with a large gas cap,thin oil rim,strong bottom water,and natural barriers faces numerous challenges,including reservoir heterogeneity,coning effects,phase changes,and multiphase flow dynamics.The influx of gas and water may lead to a low recovery of the oil rim,while reservoir heterogeneity and natural barriers further exacerbate the uneven distribution of reservoir fluid,complicating development strategies.This paper aims to investigate innovative and effective development strategies for this type of reservoir.A detailed,proportionally scaled numerical simulation is performed based on the experimental results of an artificial sand-filled model,providing novel insights into the dynamic behavior of these reservoirs.By understanding the phase behavior and fluid flow characteristics of the reservoir,the study simulates various strategies for the rational and efficient development of the gas condensate reservoir.These strategies include well patterns and completions,the decision to develop the oil rim or gas cap,depletion rates,the bottom water control,and gas injection.The results show that horizontal wells or highly deviated wells are more suitable for the development of the oil rim,as they provide larger control ranges.The presence of strong bottom water is advantageous for displacement energy supply and pressure maintenance,but it intensifies water coning effects,leading to an earlier breakthrough and a sharp production decline.Therefore,it is preferable to apply highly deviated wells at the oil-gas contact,developing the oil rim at lower rates and smaller pressure gradients,followed by developing the gas cap.This approach can reduce water coning effects and improve recovery,with oil and gas recovery reaching 24.4%and 67.95%,respectively,which is an increase of 16.74%and 17.84%compared to direct depletion development of the gas cap.Due to the strong water bottom,continuous gas injection at the top of the reservoir becomes challenging.This study introduces gas assisted gravity drainage with water control technology,a novel and highly effective approach that addresses the impact of bottom water coning effects on the oil and gas zones and overcomes the limitations of gas flooding in reservoirs with strong bottom water.This method can significantly improve oil and gas recovery,achieving recovery of 39.74%and 84.50%,respectively.Compared to the conventional depletion strategy of sequential oil rim and gas cap development,this method achieves additional improvements of 15.33%and 16.55%in oil and gas recovery,respectively.
基金the National Natural Science Foundation of China (30470556)the Program for New Century Excellent Talents in University
文摘GABAergic neurons are the major inhibitory interneurons that powerfully control the function of spinal neuronal networks.In recent years,tremendous progresses have been made in understanding the transcriptional control of GABAergic neuron development in the dorsal spinal cord.New experimental approaches provide a relatively high throughput way to study the molecular regulation of subgroup fate determination.Our understanding of the molecular mechanisms on GABAergic neuron development in the dorsal spinal cord is rapidly expanding.Recent studies have defined several transcription factors that play essential roles in GABAergic neuron development in the spinal dorsal horn.Here,we review results of very recent analyses of the mechanisms that specify the GABAergic neuron development in the dorsal spinal cord,especially the progresses in the homeodomain(HD) and basic-helix-loop-helix(bHLH) containing transcription factors.
文摘This paper will discuss the computerised developm en t control and approval system being developed for the Planning and Development C ontrol Department, City Hall of Kuala Lumpur, with stress on the GIS architectur e developed within the system. The prospects and challenges towards implementati on of the system are also discussed.
文摘Based on the research on domestic and international automatic technical development in fossil power plant,the paper analyses the recent situation of the coordinate control system between turbine and boiler of domestic fossil Power Plant,provides the development thought of coordinate control system between turbine and boiler,and describes the application prospect in control system of fossil power plant combining with the application experience.
