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A Study on the Mechanisms by Which AGEs and RAG Promote Wound Healing in Patients with Second-Degree Burns undergoing Eschar Grinding Combined with Drug Therapy
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作者 Weijie He Zhi Liu +5 位作者 Lujun Yang Sitian Xie Zhan Ouyang Yao Lin Fuhua Huang Shijie Tang 《Modern Plastic Surgery》 2025年第1期1-20,共20页
Objective: To evaluate the improvement effect of combined treatment of eschar abrasion, nanosilver dressing, and mussel mucin spray on wound healing in patients with second-degree burns, and to explore their effects o... Objective: To evaluate the improvement effect of combined treatment of eschar abrasion, nanosilver dressing, and mussel mucin spray on wound healing in patients with second-degree burns, and to explore their effects on the expression level of (advanced glycation end products) AGEs in wound tissue, so as to provide a basis for the application of AGEs expression level in wound tissue in the future clinical treatment of second-degree burns. Methods: Patients with second-degree burns admitted to the Department of Burns and Plastic Surgery of the Second Affiliated Hospital of Shantou University Medical College from July 2023 to July 2024 were selected as the research subjects. This study was a non-double-blind study, and both patients and researchers were aware of the treatment methods. They were randomly divided into Group A (control group) and Group B (study group). According to the order of their visits, the patients were numbered in advance;then the seed number was taken, and 70 random numbers were generated on the computer using SAS, the first 35 corresponding to group A, and the last 35 corresponding to group B;the random numbers were arranged from small to large, and the rank of the random numbers was the patient number;finally, the patient numbers were arranged from small to large, and the corresponding groups were the grouping scheme. 1) Wound healing time: The wound healing was observed every day, and the wound healing time was calculated when the wound was completely epithelialized. 2) Wound healing: The wound healing area was measured 1, 7, and 14 days after treatment, and transparent paper was used to record combined with a computer-assisted imaging system. Wound healing rate = wound healing area (cm2)/total wound area before treatment (cm2) × 100%. The time for complete wound healing was recorded in the two groups of patients. 3) Pain: The pain was evaluated at 1, 7, and 14 days after treatment using the visual analogue scale (VAS). The higher the score, the more severe the pain. 4) Scar condition: Scar formation was evaluated 1, 3, and 6 months after wound healing using the VAS scale, with a total score of 15 points. The higher the score, the more severe the scar. 5) Detect the expression of AGEs in wound tissue. Results: The wound healed 14.03 ± 2.28 days after eschar removal, with a cure rate of 97.8%. No infection occurred in the wound after eschar removal in all patients. The wound healing time ranged from 9 to 23 days, with an average healing time of 28.41 ± 1.45 days. The healing quality was satisfactory. The Vancouver Scar Scale scored the wound healing scar as 0.81 ± 0.73 points. Western blot was used to detect the expression of AGEs, (receptor for advanced glycation end products) RAGE, and protein in the wound tissue. Results After 7, 14, and 28 days of medication, the wounds of diabetic patients healed well. The drug treatment efficacy and hydroxyproline content showed an upward trend, and the expression levels of AGEs, RAGE, and HIF-1a proteins showed a downward trend. Compared with day 0, the hydroxyproline content of the wound granulation tissue on days 7, 14, and 28 was significantly increased (P< 0.01), and the expression levels of AGEs, RAGE, and HIF-1α proteins were significantly downregulated (P< 0.05 or P< 0.01). Conclusion: Monitoring the expression levels of AGEs and RAGE can reflect the wound-healing effect of patients with second-degree burns, and the prognosis of the wound is closely related to the expression levels of AGEs, RAGE, and scab abrasion. In the treatment of second-degree burn wounds, scab abrasion can grasp the level of necrotic scab removal, can achieve “relatively accurate” removal of necrotic tissue, maximally protect the ecological tissue between wounds and retaining normal tissue, and can play a positive role in promoting the healing process of burn wounds;at the same time, nanosilver dressings have good antibacterial properties and high safety, and mussel mucin has anti-inflammatory and antioxidant activities and the characteristics of blocking nerve endings, which can effectively relieve the burning, stinging, and itching of sensitive skin and effectively promote wound healing. 展开更多
关键词 AGES RAG DERMABRASION Second Degree burns
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Increased corn cultivation exacerbated crop residue burning in Northeast China in the 21st century
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作者 Yiqun Shang Yanyan Pei +7 位作者 Ping Fu Chuantao Ren Zhichao Li Jianfeng Ren Xinqi Zheng Yuanyuan Di Yan Zhou Jinwei Dong 《Geography and Sustainability》 2025年第3期86-97,共12页
China’s endeavors to mitigate recurrent crop residue burning(CRB)and improve air quality have yielded positive results owing to recent pollution prevention policies.Nonetheless,persistent challenges remain,particular... China’s endeavors to mitigate recurrent crop residue burning(CRB)and improve air quality have yielded positive results owing to recent pollution prevention policies.Nonetheless,persistent challenges remain,particularly in the Northeast China(NEC),where low temperature complicates crop residue management.Here,we examined the effects of cropping pattern adjustment on variations of CRB patterns in NEC during 2001-2021,utilizing the Moderate-resolution Imaging Spectroradiometer(MODIS)burned area dataset,the Visible Infrared Imaging Radiometer Suite(VIIRS)active fire dataset,and the high-accuracy crop planting area maps.Our results revealed an overall upward trend of 805.96 km^(2)/yr in NEC CRB from 2001 to 2021.The corn CRB area accounted for more than 50%of the total CRB area in each CRB-intensive year(2013-2021),and the increasing corn CRB generally aligns with the growing corn cultivation fields.A seasonal shift in CRB was found around 2017,with intensive CRB activities transitioning from both autumn and spring to primarily spring,particularly in the Songnen Plain and Sanjiang Plain.The changing trend of PM2.5 concentration aligned spatially with the shift.Moreover,the CRBs in spring of 2020 and 2021 were more severe than the major burning seasons in previous years,likely due to the disruptions during COVID-19 lockdowns.In certain years,the explanatory power of spring CRB on PM2.5 concentration was comparable to that of other natural factors,such as precipitation.This study underscores the critical need for sustained and region-specific strategies to tackle the challenges posed by CRBs. 展开更多
关键词 Crop residue burning Northeast China burned area Active fire Cropping pattern adjustment
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Analysis of anxiety and depression symptoms in adolescents with facial burns
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作者 Zhen Yu Han Zhang +1 位作者 Qian Zhang Qi-Er Wu 《World Journal of Psychiatry》 2025年第10期139-145,共7页
BACKGROUND Anxiety and depression are common psychological reactions in teenagers with facial burns and have a significant impact on their rehabilitation and quality of life.AIM To analyze anxiety and depressive sympt... BACKGROUND Anxiety and depression are common psychological reactions in teenagers with facial burns and have a significant impact on their rehabilitation and quality of life.AIM To analyze anxiety and depressive symptoms in teenagers with facial burns.METHODS We selected 50 young patients with facial burns who were treated at our hospital between October 2023 and October 2024.The Hamilton Anxiety Scale and Beck Depression Inventory were used to evaluate anxiety and depressive symptoms.Additionally,we evaluated patients'social support levels and self-esteem.Pearson's correlation analysis was used to evaluate factors related to depression and anxiety.RESULTS The overall average Hamilton Anxiety Scale score was 23.4±6.2,and 16(32%)and 34(68%)patients showed mild to moderate and moderate to severe anxiety,respectively.The overall average Beck Depression Inventory score was 18.7±7.5,and 23(46%)and 27(54%)patients had mild to moderate and moderate to severe depression,respectively.Furthermore,Pearson's correlation analysis showed a significant positive correlation between burn severity and anxiety(r=0.48,P<0.01)and depression(r=0.42,P<0.01)symptoms.Self-esteem scores and social support were significantly negatively correlated with anxiety(r=-0.55 and r=-0.40,respectively;P<0.01)and depression(r=-0.60 and r=-0.38,respectively;P<0.01 for both).CONCLUSION Adolescents with facial burns commonly experience anxiety and depressive symptoms,the severity of which is closely related to burn severity,social support,and self-esteem. 展开更多
关键词 Facial burns Adolescents ANXIETY DEPRESSION Social support SELF-ESTEEM
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Effect of adipose-derived stem cells exosomes cross-linked chitosan-αβ-glycerophosphate thermosensitive hydrogel on deep burn wounds
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作者 Lei Xu Dan Liu +4 位作者 Hai-Long Yun Wei Zhang Li Ren Wen-Wen Li Chuan Han 《World Journal of Stem Cells》 2025年第2期124-136,共13页
BACKGROUND Burn wound management is challenging,and while mesenchymal stem cellderived exosomes show therapeutic potential,optimal delivery methods are unclear.AIM To study chitosan(CS)-αβ-glycerophosphate(CS-αβ-G... BACKGROUND Burn wound management is challenging,and while mesenchymal stem cellderived exosomes show therapeutic potential,optimal delivery methods are unclear.AIM To study chitosan(CS)-αβ-glycerophosphate(CS-αβ-GP)hydrogel crosslinked with adipose-derived stem cell exosomes(ASC-Exos)for healing deep burn injuries.METHODS Rats with deep burn injuries were divided into the CS+ASCs-Exos group,the ASCs-Exos group,the CS group,and the control group.The healing rates on days 4,7,and 14 after treatment were analyzed using ImageJ software.On day 14,the tissues were stained with hematoxylin and eosin staining,Masson’s trichrome staining,and immunohistochemical analysis to evaluate tumor necrosis factorα,interleukin-6(IL-6),IL-1α,IL-10,transforming growth factorβ,and epidermal growth factor.The mRNA levels of IL-1α,CD86,C-C motif chemokine ligand 22,and CD163 were evaluated through quantitative polymerase chain reaction.RESULTS The CS+ASC-Exos group exhibited enhanced healing,reduced lymphocyte infiltration,blood vessels,and muscle fiber distribution.Increased IL-10,transforming growth factorβ,and epidermal growth factor and decreased tumor necrosis factorα,IL-1α,and IL-6 expression were observed.Quantitative polymerase chain reaction revealed reduced IL-1αand CD86 and increased C-C motif chemokine ligand 22 and CD163 expression.Protein analysis showed downregulation of phosphorylated inhibitor of kappa Balpha and P65 in the nuclear factorκB(NF-κB)pathway.ASC-Exos crosslinked with CS-αβ-GP hydrogel demonstrates superior effects in anti-inflammation,wound healing promotion,and promotion of M1 macrophage transformation to M2 macrophage by blocking the NF-κB pathway compared to ASC-Exos alone.CONCLUSION Our research demonstrates that the ASC-Exos cross-linked CS-αβ-GP hydrogel represents an advanced therapeutic approach for treating deep burn wounds.It has anti-inflammatory effects,promotes wound healing,and facilitates the transition of M1 macrophages to M2 macrophages by blocking the NF-κB pathway. 展开更多
关键词 Adipose-derived stem cells EXOSOMES HYDROGEL burn Wound healing
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Prescribed burning alters soil microbial community structure by changing soil physicochemical properties in temperate forests of northern China
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作者 Tongxin Hu Yu Han +5 位作者 Kajar Köster Jianyu Wang Haiqing Hu Xu Dou Long Sun Yiyang Ding 《Journal of Forestry Research》 2025年第2期61-77,共17页
Prescribed burning is commonly used to maintain forest ecosystem functions and reduce the risk of future wildfires.Although many studies have investigated the response of microbial community to wildfires in forest eco... Prescribed burning is commonly used to maintain forest ecosystem functions and reduce the risk of future wildfires.Although many studies have investigated the response of microbial community to wildfires in forest ecosystems,the effects of prescribed burnings on soil microbial community structure are less studied.It is also unclear that how post-fire soil physiochemical properties changes affected soil microbial communities.Here,we studied the impacts of prescribed burning on soil microbiome in three typical temperate forests of northern China by collecting soil physicochemical and high-throughput sequencing for 16S rRNA and 18S rRNA was applied to analyze the diversity and community composition of soil microbes(bacteria and fungi).Compared with pre-fire condition,prescribed burning significantly decreased Chaol index and altered soil bacterial communities(P<0.05),whereas it had no significant effect on fungal diversity and community structure of the(P>0.05).Planctomycetes and Actinobacteria made the greatest contributions to the bacterial community dissimilarity between the pre-fire and post-fire conditions.The main variables influencing the post-fire soil microbial community structure are soil pH,available phosphorus,total nitrogen,and the ratio of soil total carbon to soil total nitrogen,which could account for 73.5% of the variation in the microbial community structure in these stands.Our findings demonstrated a great discrepancy in the responses of bacteria and fungi to prescribed burning.Prescribed burning altered the soil microbial structure by modifying the physicochemical properties.Our results pointed that it is essential to evaluate the impact of prescribed burnings on forest ecosystem functions.These findings provide an important baseline for assessing post-fire microbial recovery in the region and offer critical guidance for restoration efforts. 展开更多
关键词 Prescribed burning High-throughput sequencing Temperate forest BACTERIA FUNGI
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Impact of open-field biomass burning on regional air quality in Northern India
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作者 Pooja Manwani Chandra Venkataraman Harish C.Phuleria 《Journal of Environmental Sciences》 2025年第12期126-136,共11页
Over the past decade,biomass burning has emerged as one of the main polluting events in northern India.It is one of the major sources of brown carbon(Br C),the light-absorbing organic carbon component of PM_(2.5).Most... Over the past decade,biomass burning has emerged as one of the main polluting events in northern India.It is one of the major sources of brown carbon(Br C),the light-absorbing organic carbon component of PM_(2.5).Most studies on the impact of biomass burning in India are based on source locations or urban areas;very little is known about its effects on a regional background location.We examine the effect of biomass burning on regional air quality and co-occurring meteorological factors.Year-long PM_(2.5)levels and light absorption by carbonaceous aerosols at 880 nm and 370 nm were measured at Rohtak,a regional background location.Results showed that post-harvest biomass burning in the Punjab-Haryana region affects the regional air quality with a lead of one to two days.A comparison of dispersionnormalized concentrations showed that open-field biomass burning not only affects regional air quality in the post-monsoon season(kharif crops)but is also a dominant source of PM_(2.5)in the post-harvest summer season(rabi crop).A significant(p<0.05)difference is observed in PM_(2.5),b_(abs-880),and b_(abs-370)between biomass burning days and non-biomass burning days during the kharif and rabi harvest seasons.Regression analyses confirm that in summer,regional PM_(2.5)and light absorption by aerosols are influenced more strongly by post-harvest burning of rabi crops.However,adverse meteorology plays a more dominant role in the post-monsoon season than biomass burning.These findings underscore the need for better policy interventions to curb biomass burning and improve air quality during both harvest seasons. 展开更多
关键词 Aerosol absorption coefficients Regional background Biomass burning Back trajectory Dispersion normalization
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Straw Burning Dilemma in Modern Agriculture:A Systematic Review of Driving Factors,Environmental Impacts,and Sustainable Solutions
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作者 Ghada Abd Elsattar Mohammed ORABY Fadillah PUTRA +3 位作者 MHalim NATSIR Dian SISWANTO Meshal M.ABDULLAH Ammar ABULIBDEH 《Rice science》 2025年第5期637-648,共12页
Straw burning has emerged as a persistent and multifaceted challenge within global agricultural systems,particularly across Asia,Africa,and Latin America.This review reframes straw burning not as an isolated behaviora... Straw burning has emerged as a persistent and multifaceted challenge within global agricultural systems,particularly across Asia,Africa,and Latin America.This review reframes straw burning not as an isolated behavioral issue,but as the outcome of interlinked structural,technological,and socio-cultural constraints embedded in modern agricultural transitions.Drawing on a synthesis of recent empirical studies,we identify four conceptual turning points that reshape the understanding of straw burning:the structural consequences of mechanization,the trade-offs between high-and low-tech solutions,the cultural legitimacy of burning practices,and the need for systems-based,climate-aligned management paradigms.The analysis reveals that interventions focusing solely on technical innovation often overlook the deeper institutional and cultural factors that sustain burning as a rational choice under constrained conditions.We advocate for hybrid,place-based strategies that combine accessible agronomic practices with long-term investments in infrastructure,policy alignment,and community engagement.Moving beyond fragmented solutions and adopting an integrated systems lens enables this study to contribute a forward-looking framework for sustainable straw management that is environmentally just,socially legitimate,and economically viable. 展开更多
关键词 straw burning agricultural residue management sustainable agriculture air pollution climate change
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Frailty as a sequela of burn injury:a post hoc analysis of the“RE-ENERGIZE”multicenter randomized-controlled trial and the National Health Interview Survey
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作者 Adriana C.Panayi Daren K.Heyland +9 位作者 Christian Stoppe Marc G.Jeschke Samuel Knoedler Christian Tapking Oliver Didzun Valentin Haug Amir K.Bigdeli Ulrich Kneser Dennis P.Orgill Gabriel Hundeshagen 《Military Medical Research》 2025年第6期887-902,共16页
Background:With advancements in burn treatment and intensive care leading to decreased mortality rates,a growing cohort of burn survivors is emerging.These individuals may be susceptible to frailty,characterized by re... Background:With advancements in burn treatment and intensive care leading to decreased mortality rates,a growing cohort of burn survivors is emerging.These individuals may be susceptible to frailty,characterized by reduced physiological reserve and increased vulnerability to stressors commonly associated with aging,which significantly complicates their recovery process.To date,no study has investigated burns as a potential risk factor for frailty.This study aimed to determine the short-term prevalence of frailty among burn survivors’months after injury and compare it with that of the general population.Methods:A post hoc analysis was conducted on the Randomized Trial of Enteral Glutamine to Minimize the Effects of Burn Injury(RE-ENERGIZE)trial,an international randomized-controlled trial involving 1200 burn injury patients with partial-or full-thickness burns.Participants who did not complete the 36-Item Short Form Health Survey(SF-36)questionnaire were excluded.Data for the general population were obtained from the 2022 National Health Interview Survey(NHIS).Frailty was assessed using the FRAIL(Fatigue,Resistance,Ambulation,Illness,Loss of weight)scale.Due to lack of data on loss of weight,for the purposes of this study,malnutrition was used as the fifth variable.Illness and malnutrition were based on admission data,while fatigue,resistance,and ambulation were determined from post-discharge responses to the SF-36.The burn cohort and general population groups were matched using propensity score matching and compared in terms of frailty status.Within the burn group,patients were divided into different subgroups based on their frailty status,and the differences in their(instrumental)activities of daily living(iADL and ADL)were compared.A multivariable analysis was performed within the burn cohort to identify factors predisposing to frailty as well as compromised iADL and ADL.Results:Out of the 1200 burn patients involved in the study,600 completed the required questionnaires[follow-up time:(5.5±2.3)months]and were matched to 1200 adults from the general population in the U.S.In comparison to the general population,burn patients exhibited a significantly higher likelihood of being pre-frail(42.3%vs.19.8%,P<0.0001),or frail(13.0%vs.1.0%,P<0.0001).When focusing on specific components,burn patients were more prone to experiencing fatigue(25.8%vs.13.5%,P<0.0001),limited resistance(34.0%vs.2.7%,P<0.0001),and restricted ambulation(41.8%vs.3.8%,P<0.0001).Conversely,the incidence rate of illness was observed to be higher in the general population(1.2%vs.2.8%,P=0.03),while no significant difference was detected regarding malnutrition(2.3%vs.2.6%,P=0.75).Furthermore,in comparison with robust burn patients,it was significantly more likely for pre-frail and frail patients to disclose compromise in ADL and iADL.The frail cohort reported the most pronounced limitation.Conclusions:Our findings suggest a higher incidence of post-discharge frailty among burn survivors in the short-term following injury.Burn survivors experience compromised fatigue,resistance,and ambulation,while rates of illness and malnutrition were lower or unchanged,respectively.These results underscore the critical need for early identification of frailty after a burn injury,with timely and comprehensive involvement of a multidisciplinary team including burn and pain specialists,community physicians,physiotherapists,nutritionists,and social workers.This collaborative effort can ensure holistic care to address and mitigate frailty in this patient population. 展开更多
关键词 burn injury Quality of life FRAILTY AGING Activities of daily living
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Enhancement of four-wave mixing due to coherent hole burning in a degenerate two-level system
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作者 Zhi-Yuan Liu Yi-Fan Yao +2 位作者 Yue Sun Jia-Yu Han Ying-Jie Du 《Chinese Physics B》 2025年第5期406-413,共8页
We present a theoretical study of four-wave mixing(FWM)in a degenerate two-level atomic system subject to a magnetic field whose Zeeman sublevels constitute a tripod-type atomic system,which is driven by a linearly po... We present a theoretical study of four-wave mixing(FWM)in a degenerate two-level atomic system subject to a magnetic field whose Zeeman sublevels constitute a tripod-type atomic system,which is driven by a linearly polarized field,and coupled and probed by two sets of left and right circularly polarized fields.The optical effects of coherent hole burning(CHB)and electromagnetically induced transparency(EIT)are involved in the coherent system,among which the CHB has much larger response for the FWM than the EITs.Three situations of CHB are involved,and they are the solitary CHB,overlapped CHBs,and an overlap between CHB and EIT.The overlapped CHBs have the greatest magnitude of FWM signal among the three situations.Whereas,for the overlapped CHB and EIT,it has the smallest FWM magnitude,which is no more than one tenth of the former.While for the single CHB,the FWM magnitude is half of that of the overlapped CHBs.It is noted that,in the overlap between CHB and EIT,dual EIAs can be obtained,whose FWM signal also has an enhancement in comparison to no EIA. 展开更多
关键词 four-wave mixing coherent hole burning electromagnetically induced transparency electromagnetically induced absorption
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A Tentative Discussion on the Translation of Robert Burns’ Farewell Discourse
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作者 ZHOU Yi-nuo LI Zheng-shuan 《Journal of Literature and Art Studies》 2025年第3期163-177,共15页
From the perspective of literary stylistics,this paper explores the discourse styles and Chinese translation characteristics of Robert Burns’farewell poems.Burns’farewell poems mostly appear in three types:love poem... From the perspective of literary stylistics,this paper explores the discourse styles and Chinese translation characteristics of Robert Burns’farewell poems.Burns’farewell poems mostly appear in three types:love poems,patriotic poems and animal poems,corresponding to the explicit,implicit and personified discourse styles.In the love farewell poems,the explicit ones express emotions directly by using words such as“farewell”;the implicit ones express emotions indirectly through the female perspective and the repetition of phrases.In the patriotic farewell poems,“farewell”and its phrases are used to express patriotism and the sentiment of separation.In the animal farewell poems,personification is used to endow animals with human nature,and images are used to imply death.When translating,the translator skillfully uses auxiliary words and adopts multiple translations for one word in dealing with explicit discourse;flexibly handles person and repeated phrases in implicit discourse;and conducts part-of-speech conversion and reproduces the rhythm in personified discourse.This study aims to explore how to understand the source text equivalently and express the ideas and styles of the source text appropriately,so as to achieve the standards of accuracy and vividness. 展开更多
关键词 Robert burns farewell poems Chinese translation research
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Impact of regionally transported biomass burning on carbonaceous aerosol characterization,contribution and degradation in Pu'er,Southwest China
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作者 Jianwu Shi Wenjun Rao +8 位作者 Chenyang Zhao Li Deng Xinyu Han Wei Du Jianhong Huang Senlin Tian Ping Ning Jiming Hao Yaoqian Zhong 《Journal of Environmental Sciences》 2025年第12期710-723,共14页
Biomass burning(BB)emits carbonaceous aerosols that significantly influence air quality in Southwest China during spring.To further understand the characteristics of spring BB and its original contribution to organic ... Biomass burning(BB)emits carbonaceous aerosols that significantly influence air quality in Southwest China during spring.To further understand the characteristics of spring BB and its original contribution to organic carbon(OC),daily fine particulate matter(PM_(2.5))samples were collected from March to May 2022 in Pu'er,Southwest China.The concentrations of OC,elemental carbon(EC),levoglucosan(Lev),and potassium from BB(K+BB)during the study period ranged from 5.3 to 31.2μg/m^(3),0.86-13.1μg/m^(3),0.06-0.82μg/m^(3),and 0.05-2.88μg/m^(3),respectively.To eliminate the effects of Lev degradation,this study uses the Aging of Air Mass(AAM)index to correct the atmospheric concentration of Lev and combines Bayesian mixture modeling with a molecular tracer method to assess the original contribution of BB to OC.The results indicated that the AAM index was 0.18±0.05,indicating that the degradation of Lev reached 82%.When considering the degradation of levoglucosan in the atmosphere,the primary source of BB aerosols was crop-straw combustion(71.1%),followed by the combustion of certain hardwoods and softwoods(24.9%)and grasses(4.0%).The original contribution of BB to OC was 62.4%,which was much greater than the contribution when levoglucosan degradation(23.7%)was ignored.The air mass inverse trajectories and Moderate Resolution Imaging Spectroradiometer(MODIS)fire hotspots indicated that the BB plume from Southeast Asia during spring could influence PM_(2.5)long-range transport in remote locations,and the contribution could reach 82%in Southwest China. 展开更多
关键词 Biomass burning LEVOGLUCOSAN Carbonaceous aerosols Aging of Air Mass(AAM) Bayesian mixture modeling
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Three-dimensional burning crack dynamics in constrained spherical explosive:visualization analysis and cavity-coupled pressure modeling
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作者 Chuanyu Pan Tao Li +4 位作者 Hua Fu Hailin Shang Pingchao Hu Ping Li Xilong Huang 《Defence Technology(防务技术)》 2025年第10期306-318,共13页
Accurate characterization of three-dimensional burning crack propagation remains pivotal yet challenging for energetic material safety,as conventional diagnostics and models inadequately resolve coupled crack-pressure... Accurate characterization of three-dimensional burning crack propagation remains pivotal yet challenging for energetic material safety,as conventional diagnostics and models inadequately resolve coupled crack-pressure dynamics in confined explosives.This study combines a novel spherical confinement system(with/without sapphire windows)with synchronized high-speed imaging and 3D reconstruction to overcome optical limitations in opaque explosives.Experimental analysis of centrally ignited HMX-based PBX-1 reveals:(1)burning cracks propagate radially with equatorial acceleration and polar deceleration,(2)systematic formation of 3–4 dominant crack branches across geometries,and(3)pressure evolution exhibiting gradual accumulation(subsurface cracking)followed by exponential growth(surface burn-through),with decay governed by cavity expansion.Building on Hill's framework,we develop a model incorporating cavity volume and fracture toughness criteria,validated against PBX explosive(95%HMX-based)experiments.The model demonstrates improved prediction of pressure trends compared to prior approaches,particularly in resolving laminar-phase accumulation and crackinduced surge transitions.Results establish structural cavity volume as a critical modulator of measured pressure and reveal direction-dependent crack kinematics as fundamental features of constrained combustion.This work provides experimentally validated insights into mechanisms of reaction pressure development and burning cracks pathways during constrained PBX explosive combustion. 展开更多
关键词 burning crack propagation Explosive combustion reaction Non-shock ignition Structural cavity effects Energetic material safety
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Observation on the Clinical Efficacy of Moist Burn Ointment Combined with Rotating Moxibustion in the Treatment of Pressure Ulcers with Deficiency of Qi and Blood
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作者 Song Li Dingxing Zhou 《Journal of Clinical and Nursing Research》 2025年第5期311-318,共8页
Objective:To observe the therapeutic effect of Moist Burn Ointment combined with rotating moxibustion on patients with pressure ulcers and deficiency of both Qi and blood.Methods:40 patients with pressure ulcers and d... Objective:To observe the therapeutic effect of Moist Burn Ointment combined with rotating moxibustion on patients with pressure ulcers and deficiency of both Qi and blood.Methods:40 patients with pressure ulcers and deficiency of both Qi and blood were randomly divided into two groups from July 2024 to November 2025.Group A received Moist Burn Ointment combined with rotating moxibustion,while Group B received Moist Burn Ointment only.Results:Group A showed better efficacy,wound healing time,dressing change frequency,satisfaction,PUSH score,and adverse reaction indicators compared to Group B(P<0.05).Conclusion:The combination of Moist Burn Ointment and rotating moxibustion in the treatment of patients with pressure ulcers and deficiency of both Qi and blood can shorten wound healing time,reduce dressing change frequency,and alleviate the degree of pressure ulcers,which is safe and efficient. 展开更多
关键词 Pressure ulcer Deficiency of both Qi and blood Rotating moxibustion Moist burn Ointment EFFICACY
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Spreadable thermosensitive nanocomposite hydrogel dressing with ultrasound-responsive bactericidal/repair-promoting regulation and cascade antioxidantion for infected burn wound repair
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作者 Meng Yu Yi Guo +4 位作者 Shaowen Zhou Yanhuai Li Zexing Deng Xin Zhao Yong Han 《Journal of Materials Science & Technology》 2025年第16期189-204,共16页
Treating severe burn wounds poses significant challenges,including considerable cell loss,excessive inflammation,and a high susceptibility to bacterial infections.Ideal burn dressings should exhibit excellent antibact... Treating severe burn wounds poses significant challenges,including considerable cell loss,excessive inflammation,and a high susceptibility to bacterial infections.Ideal burn dressings should exhibit excellent antibacterial properties,anti-inflammatory effects,and promote cell proliferation.Additionally,they need facilitate painless dressing changes and be user-friendly.Herein,we synthesized a thermosensitive hydrogel by crosslinking poly(N-isopropylacrylamide-co-allyloxybenzaldehyde)(PNA)and amino-terminated Pluronic F127(APF)through a Schiffbase reaction.It exhibited reversible gelsol transition and spread-ability.By incorporating piezoelectric gold nanoparticle-modified barium titanate(Au@BaTiO3)and cas-cade antioxidant MOF-818,a nanocomposite hydrogel dressing with diverse bioactive functionalities was developed.Results demonstrated that the nanocomposite hydrogel possessed gel-sol transition properties,maintained a stable gel state within a broad temperature range,and desirable self-healing property.Au@BaTiO3 exhibited good piezoelectric properties and ROS generation upon ultrasound stimulation,while MOF-818 displayed highly efficient cascade nanozyme activity.The combination of Au@BaTiO3 and MOF-818 promoted fibroblast proliferation and migration,reduced intracellular ROS levels,and induced anti-inflammatory polarization of macrophages under ultrasound stimulation.In vitro and in vivo antibacterial results disclosed that the nanocomposite hydrogel had excellent antibacterial activity under highintensity ultrasound stimulation.When applied to infected burn wounds,the nanocomposite hydrogel can rapidly sterilize the wound upon initial high-intensity ultrasound,and then reduce inflammation and promote M2 macrophage polarization by the following low-intensity ultrasound stimulation,and thus accelerating the healing by improving granulation tissue formation,angiogenesis,and collagen deposition. 展开更多
关键词 Thermosensitive nanocomposite hydrogel Piezoelectric nanoparticles MOF nanozyme Bactericidal/repair-promoting regulation Infected burn wound
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Severity assessment of burned skin based on anisotropy of optical coherence elastography
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作者 Heng Liu Di Yang +4 位作者 Renfei Jia Weike Wang Lili Shao Quanzhong Liu Yanmei Liang 《Journal of Innovative Optical Health Sciences》 2025年第5期79-88,共10页
Distinguishing the severity of burned skin from structural optical coherence tomography(OCT)intensity maps remains a challenging task,and functional imaging from an elastic perspective can improve the accuracy of burn... Distinguishing the severity of burned skin from structural optical coherence tomography(OCT)intensity maps remains a challenging task,and functional imaging from an elastic perspective can improve the accuracy of burned skin examination.As a functional extension of OCT,optical coherence elastography(OCE)can reveal the mechanical properties of samples while inheriting the imaging advantages of OCT.In this study,we used OCE to reveal the shear modulus and anisotropy parameters of burned skin before and after burning.A porcine skin burn model was constructed at a series of burned time durations and tested by elastic anisotropy imaging.Normal skin after hydration maintains good consistency in shear modulus.Interestingly,the shear modulus and longitudinal modulus of the burned skin show a tendency to stepwise increase with increasing burned times.A dataset was constructed by sampling the modulus parameters of burned skin maps through a scratch window,and its category was automatically identi¯ed by Kmeans and density peak clustering(DPC)algorithms with good agreement.The elastic anisotropy-based skin burn assessment method shows a prospect to be supplemented into the nondestructive means of burned skin examination. 展开更多
关键词 Dynamic optical coherence elastography elastic anisotropy severity assessment of burned skin.
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Global Fire Season Types and Their Characteristics Based on MODIS Burned Area Data
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作者 ZHANG Weihan LIU Ronggao +2 位作者 HE Jiaying LIU Yang WU Chao 《Chinese Geographical Science》 2025年第2期374-383,共10页
Fire season affects the dynamic changes of post-fire vegetation communities and carbon emissions.Analyzing its global patterns supports understanding of the ecological impacts of fires and responses of fires to climat... Fire season affects the dynamic changes of post-fire vegetation communities and carbon emissions.Analyzing its global patterns supports understanding of the ecological impacts of fires and responses of fires to climate change.Meteorological variables have been widely used to quantify fire season in current studies.However,their results can not be used to assess climate impacts on the seasonality of fire activities.Here we utilized satellite-based Moderate Resolution Imaging Spectroradiometer(MODIS)burned area data from 2001 to 2022 to identify global fire season types based on the number of peaks within a year.Using satellite data and innovatively processing the data to obtain a more accurate length of the fire season.We divided fire season types and examined the spatial distribution of fire season types across the Koppen-Geiger climate(KGC)zones.At a global scale,we identified three major fire season types,including unimodal(31.25%),bimodal(52.07%),and random(16.69%).The unimodal fire season primarily occurs in boreal and tropical regions lasting about 2.7 mon.In comparison,temperate ecosystems tend to have a longer fire season(3 mon)with two peaks throughout the year.The KGC zones show divergent contributions from the fire season types,indicating potential impacts of the climatic conditions on fire seasonality in these regions. 展开更多
关键词 fire season fire season types Moderate Resolution Imaging Spectroradiometer(MODIS) burned area data Köppen-Geiger climate classification system global terrestrial ecosystems
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Prediction of area burned under climatic change scenarios:A case study in the Great Xing'an Mountains boreal forest 被引量:7
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作者 杨光 邸雪颖 +3 位作者 曾涛 舒展 王超 于宏洲 《Journal of Forestry Research》 SCIE CAS CSCD 2010年第2期213-218,I0007,共7页
Monthly projections of maximum temperature,relative humidity,precipitation,and wind speed were made based on the model of HadCM3 and the climatic change scenarios of IPCC SRES A2a and B2a for the future scenario perio... Monthly projections of maximum temperature,relative humidity,precipitation,and wind speed were made based on the model of HadCM3 and the climatic change scenarios of IPCC SRES A2a and B2a for the future scenario periods of 2010–2039(referred to as 2020s),2040–2069(referred to as 2050s),and 2070–2099(referred to as 2080s).The period 1961–1990 was chosen as the baseline period.The observed and projected weather data were downscaled using delta change methods and historical relationships between weather data,area burned,and the seasonal severity rating(SSR) code of the Canadian Fire Weather Index System were examined.The variations of area burned as influenced by climate change were assessed quantitative and qualitative for the study region,assuming that the fire regimes had the similar responses to the warming climate as during the 20th century.Our results indicated that a linear regression relationship existing between the historical area burned and the mean SSR values with regression coefficient in the significant range of 0.16 to 0.61.It was evident that the increased SSR values could result in more area burned;the area burned in the study region would have an increasing pattern during the 21st century under scenarios A2a and B2a scenarios and the area burned would be doubled.Also,the future area burned would have a strong seasonal pattern that more fires would occur in summer and autumn fire season,especially in summer.The area burned in summer fire season would increase by 1.5 times compared to that in the baseline period in 2080s under A2a scenarios. 展开更多
关键词 climatic warming forest fire area burned FORECAST
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天然药物化学史话:20世纪最伟大的天然有机化学家--Robert Burns Woodward 被引量:3
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作者 王于方 付炎 +5 位作者 吴一兵 张嫚丽 霍长虹 李力更 顾玉诚 史清文 《中草药》 CAS CSCD 北大核心 2017年第8期1484-1498,共15页
Robert Burns Woodward是著名的天然有机化学大师。简单介绍Woodward教授生平,回顾他的主要研究成就,尤其在天然产物化学领域的卓越贡献,其中包括天然产物全合成、利用各种光谱手段进行天然产物结构鉴定、化学理论研究、生物合成研究等... Robert Burns Woodward是著名的天然有机化学大师。简单介绍Woodward教授生平,回顾他的主要研究成就,尤其在天然产物化学领域的卓越贡献,其中包括天然产物全合成、利用各种光谱手段进行天然产物结构鉴定、化学理论研究、生物合成研究等。谨以此纪念这位20世纪最伟大的有机化学家100周年诞辰。 展开更多
关键词 Robert burnS Woodward 天然药物化学 天然产物 全合成 结构研究 光谱技术
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MCBurn——MCNP和ORIGEN耦合程序系统 被引量:27
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作者 余纲林 王侃 王煜宏 《原子能科学技术》 EI CAS CSCD 2003年第3期250-254,共5页
介绍了MCNP和ORIGEN耦合程序系统MCBurn的理论模型,选取了一个压水堆栅元燃耗计算基准问题(3种燃耗深度)对MCBurn进行验证。结果表明:MCBurn关于反应性和核素成分的计算结果与实验测量值和其它程序的结果符合良好,且MCBurn在某些计算结... 介绍了MCNP和ORIGEN耦合程序系统MCBurn的理论模型,选取了一个压水堆栅元燃耗计算基准问题(3种燃耗深度)对MCBurn进行验证。结果表明:MCBurn关于反应性和核素成分的计算结果与实验测量值和其它程序的结果符合良好,且MCBurn在某些计算结果、参数选择确定方式和程序自动执行等方面优于类似国外程序。 展开更多
关键词 MCburn MCNP ORIGEN 耦合程序系统 压水堆 燃耗计算基准 计算机程序
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Research advance in forest restoration on the burned blanks 被引量:3
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作者 孔繁花 李秀珍 +1 位作者 赵善伦 尹海伟 《Journal of Forestry Research》 SCIE CAS CSCD 2003年第2期180-184,共5页
How to restore the destroyed forest after forest fire is a key question that man must face. This paper reviewed the research situation and history on the forest restoration burned blanks and summed up the research met... How to restore the destroyed forest after forest fire is a key question that man must face. This paper reviewed the research situation and history on the forest restoration burned blanks and summed up the research methods used into four scales: seed-bank scale, community scale, ecosystem scale and landscape scale. The new technologies such as GIS & Remote Sensing used to vegetation restoration were also summarized. The strategies and developing trend of vegetation restoration research on burned blanks were discussed. 展开更多
关键词 burned blanks Forest restoration Research advance Questions and countermeasures
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