Objective The objective of this report was to demonstrate the clinical application of free flow-through anterolateral thigh flaps for the treatment of high-tension electrical wrist burns.Methods We collected the data ...Objective The objective of this report was to demonstrate the clinical application of free flow-through anterolateral thigh flaps for the treatment of high-tension electrical wrist burns.Methods We collected the data of 8 patients with high-tension electrical wrist burns admitted to Beijing Jishuitan Hospital from January 2014 to December 2018.The clinical and pathological data were extracted from electronic hospital medical records.We obtained follow-up information through clinic visits.Results The injury sites for all 8 patients were the wrists,specifically 5 right and 3 left wrists,all of which were on the flexor side.Five patients had ulnar artery embolism necrosis and patency,with injury to the radial artery.Two patients had ulnar and radial arterial embolization and necrosis.The last patient had ulnar arterial embolization and necrosis with a normal radial artery.After debridement,the wound area ranged from 12 cm×9 cm to 25 cm×16 cm.The diagnoses for the eight patients were type II to type III high-tension electrical wrist burns.Free flow-through anterolateral thigh flaps(combined with great saphenous vein transplantation if necessary)were used to repair the wounds.The prognosis for all patients was good after six months to one year of follow-up.Conclusion Treating wrist types II and III high-tension electrical burns is still challenging in clinical practice.The use of free flow-through anterolateral thigh flaps(combined with great saphenous vein transplantation if necessary)to repair the wound and to restore the blood supply for the hand at the same time is a good choice for treating severe wrist electrical burns.展开更多
AIM To look into the management options of early debridement of the wound, followed by vascularized cover to bring in fresh blood supply to remaining tissue in electrical burns. METHODS A total of 16 consecutive patie...AIM To look into the management options of early debridement of the wound, followed by vascularized cover to bring in fresh blood supply to remaining tissue in electrical burns. METHODS A total of 16 consecutive patients sustaining full thickness forearm burns over a period of one year were included in the study group. Debridement was undertaken within 48 h in 13 patients. Three patients were taken for debridement after 48 h. Debridement was repeated within 2-4 d after daily wound assessment and need for further debridement. RESULTS On an average two debridements(range 1-4) was required in our patients for the wound to be ready for definitive cover. Interval between each debridement ranged from 2-18 d. Fourteen patients were provided vascularized cover after final debridement(6 free flaps, 8 pedicled flaps). Functional assessment of gross hand function done at 6 wk, 2 mo, 3 mo and 6 mo follow-up. CONCLUSION High-tension electrical burns lead to significant morbi-dity. These injuries are best managed by early decompression followed by multiple serial debridements. The ideal timing of free flap coverage needs further investigation.展开更多
BACKGROUND Electrical burns are devastating injuries and can cause deep burns with significant morbidity and delayed sequelae.Epidemiological data regarding the etiology,socioeconomic differences and geographic variat...BACKGROUND Electrical burns are devastating injuries and can cause deep burns with significant morbidity and delayed sequelae.Epidemiological data regarding the etiology,socioeconomic differences and geographic variation are necessary to assess the disease burden and plan an effective preventive strategy.These severe injuries often lead to amputations and thus hamper quality of life in the long term AIM To identify the population at maximum risk of sustaining electrical burns.We also studied the impact of electrical burns on these patients in terms of quality of life as well as return to work.METHODS The study was conducted at a tertiary referral teaching hospital over a period of eighteen months.All patients with a history of sustaining electrical burns and satisfying the inclusion criteria were included in the study.All relevant epidemiological parameters and treatment details were recorded.The patients were subsequently followed up at 3 mo,6 mo and 9 mo.The standardized Brief Version of the Burn Specic Health Scale(BSHS-B)was adopted to assess quality of life.Statistical analysis was conducted using IBM SPSS statistics(version 22.0).A P value of<0.05 was considered statistically significant.RESULTS A total of 103 patients were included in the study.The mean age of the patients was 31.83 years(range 18-75 years).A significant majority(91.3%)of patients were male.The mean total body surface area(TBSA)in these patients was 21.1%.In most of the patients(67%),the injury was occupation-related.High voltage injuries were implicated in 72.8%of patients.Among the 75 high voltage burn patients,31(41%)required amputation.The mean number of surgeries the patients underwent in hospital was 2.03(range 1 to 4).The quality of life parameters amongst the patients sustaining high voltage electrical burns were poorer when compared to low voltage injuries at all follow-up intervals across nine domains.In eight of these domains,the difference was statistically significant.Similarly,the scores among the amputees were poorer when compared to non-amputees.The difference was statistically significant in six domains.CONCLUSION Electrical burns remain a problem in the developing world.Most injuries are occupation-related.The quality of life in patients with high voltage burns and amputees remains poor.Work resumption was almost impossible for amputees.These patients could not regain pre-injury status.Steps should be taken to create awareness and to implement an effective preventive strategy to safeguard against electrical injuries.展开更多
We reported a case of a 30-year-old man who reportedly sustained electrical burns and fell from a high voltage electric pole about 50 meter high onto a metal that caused impalement injury.In addition,he sustained full...We reported a case of a 30-year-old man who reportedly sustained electrical burns and fell from a high voltage electric pole about 50 meter high onto a metal that caused impalement injury.In addition,he sustained full-thickness burns of the right upper limb(7%),the right hemithorax,the perineum(sparing the penis),the anterior abdominal wall and the lateral aspect of both thighs.There was 43%burned surface area in total.Radiographic examination revealed a slender curved object extending from his perineum into the pelvis.The management of this case was a challenging one which was described in this article.展开更多
This study was conducted to investigate the characteristics of meso-scale combustion.The technique of electrical capacitance tomography(ECT) was used to locate flame position and monitor the effect corresponding to va...This study was conducted to investigate the characteristics of meso-scale combustion.The technique of electrical capacitance tomography(ECT) was used to locate flame position and monitor the effect corresponding to varied air/fuel ratio in a meso-scale combustor.Combustion phenomena including igniting,quenching and unsteady combustion have been visualized using ECT.The method of metallization protecting ECT sensor from high temperature damage and the novel calibration method adapted to ECT monitoring of unknown permittivity flame have been shown to be successful.At the same time,electrical nature of combustion and dielectric characteristics of hy-drocarbon flame were studied.The relationship between flame permittivity and state parameters of combustion gas was demonstrated preliminarily.展开更多
An arc model considering deviations from thermodynamic and chemical equilibrium has been developed in order to achieve a better understanding of the arc plasma close to material surfaces.The model is based on unified ...An arc model considering deviations from thermodynamic and chemical equilibrium has been developed in order to achieve a better understanding of the arc plasma close to material surfaces.The model is based on unified consideration of the thermionic tungsten cathode,the arc region and the flat anode made of copper.The heat transfer within the electrodes is coupled with the plasma through the energy fluxes onto the electrode boundaries.Electrical characteristics of an 8 mm long free-burning arc are presented along with findings from spectroscopic measurements of the plasma emission in atmospheric pressure argon.The arc current varied from 60 A up to 200 A,and the gas flow rate was set at 12 L/min(at atmospheric pressure,room temperature).展开更多
Laser-induced aerosols,predominantly submicron in size,pose significant environmental and health risks during the decommissioning of nuclear reactors.This study experimentally investigated the removal of laser-generat...Laser-induced aerosols,predominantly submicron in size,pose significant environmental and health risks during the decommissioning of nuclear reactors.This study experimentally investigated the removal of laser-generated aerosol particles using a water spray system integrated with an innovative system for pre-injecting electrically charged mist in our facility.To simulate aerosol generation in reactor decommissioning,a high-power laser was used to irradiate various materials(including stainless steel,carbon steel,and concrete),generating aerosol particles that were agglomerated with injected water mist and subsequently scavenged by water spray.Experimental results demonstrate enhanced aerosol removal via aerosol-mist agglomeration,with charged mist significantly improving particle capture by increasing wettability and size.The average improvements for the stainless steel,carbon steel,and concrete were 40%,44%,and 21%,respectively.The results of experiments using charged mist with different polarities(both positive and negative)and different surface coatings reveal that the dominant polarity of aerosols varies with the irradiated materials,influenced by their crystal structure and electron emission properties.Notably,surface coatings such as ZrO_(2)and CeO_(2)were found to possibly alter aerosol charging characteristics,thereby affecting aerosol removal efficiency with charged mist configurations.The innovative aerosol-mist agglomeration approach shows promise in mitigating radiation exposure,ensuring environmental safety,and reducing contaminated water during reactor dismantling.This study contributes critical knowledge for the development of advanced aerosol management strategies for nuclear reactor decommissioning.The understanding obtained in this work is also expected to be useful for various environmental and chemical engineering applications such as gas decontamination,air purification,and pollution control.展开更多
Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance to...Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance tomography enables real-time monitoring of changes in cerebral blood perfusion within the ischemic brain,but investigating the feasibility of using this method to assess post-stroke rehabilitation in vivo remains critical.In this study,ischemic stroke was induced in rats through middle cerebral artery occlusion surgery.Transcranial focused ultrasound stimulation was used to treat the rat model of ischemia,and electrical impedance tomography was used to measure impedance during both the acute stage of ischemia and the rehabilitation stage following the stimulation.Electrical impedance tomography results indicated that cerebral impedance increased after the onset of ischemia and decreased following transcranial focused ultrasound stimulation.Furthermore,the stimulation promoted motor function recovery,reduced cerebral infarction volume in the rat model of ischemic stroke,and induced the expression of brain-derived neurotrophic factor in the ischemic brain.Our results also revealed a significant correlation between the impedance of the ischemic brain post-intervention and improvements in behavioral scores and infarct volume.This study shows that daily administration of transcranial focused ultrasound stimulation for 20 minutes to the ischemic hemisphere 24 hours after cerebral ischemia enhanced motor recovery in a rat model of ischemia.Additionally,our findings indicate that electrical impedance tomography can serve as a valuable tool for quantitatively evaluating rehabilitation after ischemic stroke in vivo.These findings suggest the feasibility of using impedance data collected via electrical impedance tomography to clinically assess the effects of rehabilitatory interventions for patients with ischemic stroke.展开更多
The major aim of stroke therapy is to stimulate brain repair and improve behavioral recovery after cerebral ischemia.One option is to stimulate endogenous neurogenesis in the subventricular zone and direct the newly f...The major aim of stroke therapy is to stimulate brain repair and improve behavioral recovery after cerebral ischemia.One option is to stimulate endogenous neurogenesis in the subventricular zone and direct the newly formed neurons to the damaged area.However,only a small percentage of these neurons survive,and many do not reach the damaged area,possibly because the corpus callosum impedes the migration of subventricular zone-derived stem cells into the lesioned cortex.A second major obstacle to stem cell therapy is the strong inflammatory reaction induced by cerebral ischemia,whereby the associated phagocytic activity of brain macrophages removes both therapeutic cells and/or cell-based drug carriers.To address these issues,neurogenesis was electrically stimulated in the subventricular zone,followed by isolation of proliferating cells,including newly formed neurons,which were subsequently mixed with a nutritional hydrogel.This mixture was then transferred to the stroke cavity of day 14 post-stroke mice.We found that the performance of the treated animals improved in behavioral tests,including novel object,open field,hole board,grooming,and“time-to-feel”adhesive tape tests.Furthermore,immunostaining revealed that the stem cell marker nestin,the neuroepithelial marker Mash1,and the immature neuronal marker doublecortin-positive cells survived in the transplanted area for 2 weeks,possibly due to reduced phagocytic activity and supportive angiogenesis.These results clearly indicate that the transplantation of committed subventricular zone stem cells combined with a protective nutritional gel directly into the infarct cavity after the peak of stroke-induced neuroinflammation represents a feasible approach to improve neurorestoration after cerebral ischemia.展开更多
Electrical impedance tomography(EIT)is a non-invasive imaging modality that generates real-time images by measuring tissue bioimpedance.It works by applying current and collecting voltage data to reconstruct images of...Electrical impedance tomography(EIT)is a non-invasive imaging modality that generates real-time images by measuring tissue bioimpedance.It works by applying current and collecting voltage data to reconstruct images of electrical conductivity,refl ecting tissue properties.[1]We aim to off er a comprehensive guide to the fundamental technology behind EIT and to explore its clinical applications across both pulmonary and extrapulmonary domains.展开更多
China’s endeavors to mitigate recurrent crop residue burning(CRB)and improve air quality have yielded positive results owing to recent pollution prevention policies.Nonetheless,persistent challenges remain,particular...China’s endeavors to mitigate recurrent crop residue burning(CRB)and improve air quality have yielded positive results owing to recent pollution prevention policies.Nonetheless,persistent challenges remain,particularly in the Northeast China(NEC),where low temperature complicates crop residue management.Here,we examined the effects of cropping pattern adjustment on variations of CRB patterns in NEC during 2001-2021,utilizing the Moderate-resolution Imaging Spectroradiometer(MODIS)burned area dataset,the Visible Infrared Imaging Radiometer Suite(VIIRS)active fire dataset,and the high-accuracy crop planting area maps.Our results revealed an overall upward trend of 805.96 km^(2)/yr in NEC CRB from 2001 to 2021.The corn CRB area accounted for more than 50%of the total CRB area in each CRB-intensive year(2013-2021),and the increasing corn CRB generally aligns with the growing corn cultivation fields.A seasonal shift in CRB was found around 2017,with intensive CRB activities transitioning from both autumn and spring to primarily spring,particularly in the Songnen Plain and Sanjiang Plain.The changing trend of PM2.5 concentration aligned spatially with the shift.Moreover,the CRBs in spring of 2020 and 2021 were more severe than the major burning seasons in previous years,likely due to the disruptions during COVID-19 lockdowns.In certain years,the explanatory power of spring CRB on PM2.5 concentration was comparable to that of other natural factors,such as precipitation.This study underscores the critical need for sustained and region-specific strategies to tackle the challenges posed by CRBs.展开更多
As a matured technique used in many fields,the distributed computer system is still a new management method for the aeronautical electrical power distribution system in our country. In this paper, a novel aircraft ele...As a matured technique used in many fields,the distributed computer system is still a new management method for the aeronautical electrical power distribution system in our country. In this paper, a novel aircraft electrical power distribution system based on the distributed computer system is proposed. The principles, features and structure of the aircraft electrical power distribution system and the distributed computer system named electrical load management system (ELMS) are studied. The ELMS composed of four electrical load management centers (ELMCs) and two power source processors (PSPs) operates in the 1553B buses. Principles of the ELMCs and the PSPs are introduced. With the application of the distributed computer system, the aircraft electrical power distribution system is simple, adaptable and flexible.展开更多
The excellent mechanical properties make graphene promising for realizing nanomechanical resonators with high resonant frequencies,large quality factors,strong nonlinearities,and the capability to efectively interface...The excellent mechanical properties make graphene promising for realizing nanomechanical resonators with high resonant frequencies,large quality factors,strong nonlinearities,and the capability to efectively interface with various physical systems.Equipped with gate electrodes,it has been demonstrated that these exceptional device properties can be electrically manipulated,leading to a variety of nanomechanical/acoustic applications.Here,we review the recent progress of graphene nanomechanical resonators with a focus on their electrical tunability.First,we provide an overview of diferent graphene nanomechanical resonators,including their device structures,fabrication methods,and measurement setups.Then,the key mechanical properties of these devices,for example,resonant frequencies,nonlinearities,dissipations,and mode coupling mechanisms,are discussed,with their behaviors upon electrical gating being highlighted.After that,various potential classical/quantum applications based on these graphene nanomechanical resonators are reviewed.Finally,we briefy discuss challenges and opportunities in this feld to ofer future prospects for the ongoing studies on graphene nanomechanical resonators.展开更多
Transcutaneous electrical acupoint stimulation(TEAS)is a kind of physical therapy that use electric cur-rent through the electrodes placed on the surface of acupoints to produce clinical effects in the human body,whic...Transcutaneous electrical acupoint stimulation(TEAS)is a kind of physical therapy that use electric cur-rent through the electrodes placed on the surface of acupoints to produce clinical effects in the human body,which is characterized by less adverse reaction and convenient operation.It has been widely used in the treatment of various diseases.This review introduces six major clinical applications of TEAS,named analgesia,regulation of gastrointestinal function,improvement of reproductive function,enhancement of cognitive function,promotion of limb function recovery and relief of fatigue.Besides,TEAS has been ap-plied to the treatment of other chronic diseases such as hypertension and diabetes,achieving satisfactory clinical effects.However,two crucial challenges are encountered in the development of TEAS.One is the lack of standardization in the selection of parameters such as waveform,frequency,intensity and stimula-tion duration.The other is the limitation on the flexibility in the acupoint selection.This review analyzes key issues that need to be addressed in the current clinical application of TEAS,such as the selection of parameters and acupoints,and this review provides a certain reference value for optimizing regimens of TEAS and promoting its development and application.展开更多
Thermally conductive papers with electrical insulation and mechanical robustness are essential for efficient thermal management in modern electronics.In this study,we introduced a metal ion-assisted interfacial crossl...Thermally conductive papers with electrical insulation and mechanical robustness are essential for efficient thermal management in modern electronics.In this study,we introduced a metal ion-assisted interfacial crosslinking strategy to strengthen sugarfunctionalized graphene fluoride(SGF)and cellulose nanofibers(CNF)by hydrogen bonding and metal ion crosslinking that leads to simultaneous enhancements in thermal conductivity and mechanical properties.The facile sugarassisted ball-milling exfoliation method was developed to achieve the exfoliation of graphite fluoride and hydroxyl group functionalization on the surface of graphene fluoride.Thanks to the good dispersibility of the SGF sheets in water,the flexible SGF/CNF composite papers with hydrogen bonding were prepared via vacuum-assisted filtration.We introduced hydrogen bonding and metal ion crosslinking into SGF/CNF papers to obtain densely packed composite papers.Ca^(2+)or Al^(3+)ion-crosslinked SGF/CNF papers exhibited superior thermal and mechanical properties owing to hydrogen bonding and metal ion crosslinking.SGF/CNF-Ca^(2+)and SGF/CNF-Al^(3+)papers at 50 wt%of SGF yield in-plane thermal conductivities of 72.93 and 75.02 W m^(-1) K^(-1),and tensile strengths of 121.5 and 135.7 MPa,respectively.A thermal percolation value was observed at 12.6 vol%of SGF filler content.In addition,the SGF/CNF papers exhibited electrical insulation properties.These remarkable characteristics of the metal ion-crosslinked SGF/CNF papers are attributed to the densely packed structures caused by the strong interfacial interactions from hydrogen bonding as well as metal ion-crosslinking that could promote phonon transport.High-performance metal ion-crosslinked SGF/CNF papers with these fascinating advantages offer great potential for the thermal management of flexible electronics.展开更多
Aramid papers (AP), made of aramid fibers, demonstrate superiority in electrical insulation applications. Unfortunately, the strength and electrical insulating properties of AP remain suboptimal, primarily due to the ...Aramid papers (AP), made of aramid fibers, demonstrate superiority in electrical insulation applications. Unfortunately, the strength and electrical insulating properties of AP remain suboptimal, primarily due to the smooth surface and chemical inertness of aramid fibers. Herein, AP are modified via the nacre-mimetic structure composed of aramid nanofibers (ANF) and carbonylated basalt nanosheets (CBSNs). This is achieved by impregnating AP into an ANF-CBSNs (A-C) suspension containing a 3D ANF framework as the matrix and 2D CBSNs as fillers. The resultant biomimetic composite papers (AP/A-C composite papers) exhibit a layered “brick-and-mortar” structure, demonstrating superior mechanical and electrical insulating properties. Notably, the tensile strength and breakdown strength of AP/A-C5 composite papers reach 39.69 MPa and 22.04 kV mm^(−1), respectively, representing a 155 % and 85 % increase compared to those of the control AP. These impressive properties are accompanied with excellent volume resistivity, exceptional dielectric properties, impressive folding endurance, outstanding heat insulation, and remarkable flame retardance. The nacre-inspired strategy offers an effective approach for producing highly promising electrical insulating papers for advanced electrical equipment.展开更多
Karst fractures serve as crucial seepage channels and storage spaces for carbonate natural gas reservoirs,and electrical image logs are vital data for visualizing and characterizing such fractures.However,the conventi...Karst fractures serve as crucial seepage channels and storage spaces for carbonate natural gas reservoirs,and electrical image logs are vital data for visualizing and characterizing such fractures.However,the conventional approach of identifying fractures using electrical image logs predominantly relies on manual processes that are not only time-consuming but also highly subjective.In addition,the heterogeneity and strong dissolution tendency of karst carbonate reservoirs lead to complexity and variety in fracture geometry,which makes it difficult to accurately identify fractures.In this paper,the electrical image logs network(EILnet)da deep-learning-based intelligent semantic segmentation model with a selective attention mechanism and selective feature fusion moduledwas created to enable the intelligent identification and segmentation of different types of fractures through electrical logging images.Data from electrical image logs representing structural and induced fractures were first selected using the sliding window technique before image inpainting and data augmentation were implemented for these images to improve the generalizability of the model.Various image-processing tools,including the bilateral filter,Laplace operator,and Gaussian low-pass filter,were also applied to the electrical logging images to generate a multi-attribute dataset to help the model learn the semantic features of the fractures.The results demonstrated that the EILnet model outperforms mainstream deep-learning semantic segmentation models,such as Fully Convolutional Networks(FCN-8s),U-Net,and SegNet,for both the single-channel dataset and the multi-attribute dataset.The EILnet provided significant advantages for the single-channel dataset,and its mean intersection over union(MIoU)and pixel accuracy(PA)were 81.32%and 89.37%,respectively.In the case of the multi-attribute dataset,the identification capability of all models improved to varying degrees,with the EILnet achieving the highest MIoU and PA of 83.43%and 91.11%,respectively.Further,applying the EILnet model to various blind wells demonstrated its ability to provide reliable fracture identification,thereby indicating its promising potential applications.展开更多
Objective: To evaluate the improvement effect of combined treatment of eschar abrasion, nanosilver dressing, and mussel mucin spray on wound healing in patients with second-degree burns, and to explore their effects o...Objective: To evaluate the improvement effect of combined treatment of eschar abrasion, nanosilver dressing, and mussel mucin spray on wound healing in patients with second-degree burns, and to explore their effects on the expression level of (advanced glycation end products) AGEs in wound tissue, so as to provide a basis for the application of AGEs expression level in wound tissue in the future clinical treatment of second-degree burns. Methods: Patients with second-degree burns admitted to the Department of Burns and Plastic Surgery of the Second Affiliated Hospital of Shantou University Medical College from July 2023 to July 2024 were selected as the research subjects. This study was a non-double-blind study, and both patients and researchers were aware of the treatment methods. They were randomly divided into Group A (control group) and Group B (study group). According to the order of their visits, the patients were numbered in advance;then the seed number was taken, and 70 random numbers were generated on the computer using SAS, the first 35 corresponding to group A, and the last 35 corresponding to group B;the random numbers were arranged from small to large, and the rank of the random numbers was the patient number;finally, the patient numbers were arranged from small to large, and the corresponding groups were the grouping scheme. 1) Wound healing time: The wound healing was observed every day, and the wound healing time was calculated when the wound was completely epithelialized. 2) Wound healing: The wound healing area was measured 1, 7, and 14 days after treatment, and transparent paper was used to record combined with a computer-assisted imaging system. Wound healing rate = wound healing area (cm2)/total wound area before treatment (cm2) × 100%. The time for complete wound healing was recorded in the two groups of patients. 3) Pain: The pain was evaluated at 1, 7, and 14 days after treatment using the visual analogue scale (VAS). The higher the score, the more severe the pain. 4) Scar condition: Scar formation was evaluated 1, 3, and 6 months after wound healing using the VAS scale, with a total score of 15 points. The higher the score, the more severe the scar. 5) Detect the expression of AGEs in wound tissue. Results: The wound healed 14.03 ± 2.28 days after eschar removal, with a cure rate of 97.8%. No infection occurred in the wound after eschar removal in all patients. The wound healing time ranged from 9 to 23 days, with an average healing time of 28.41 ± 1.45 days. The healing quality was satisfactory. The Vancouver Scar Scale scored the wound healing scar as 0.81 ± 0.73 points. Western blot was used to detect the expression of AGEs, (receptor for advanced glycation end products) RAGE, and protein in the wound tissue. Results After 7, 14, and 28 days of medication, the wounds of diabetic patients healed well. The drug treatment efficacy and hydroxyproline content showed an upward trend, and the expression levels of AGEs, RAGE, and HIF-1a proteins showed a downward trend. Compared with day 0, the hydroxyproline content of the wound granulation tissue on days 7, 14, and 28 was significantly increased (P< 0.01), and the expression levels of AGEs, RAGE, and HIF-1α proteins were significantly downregulated (P< 0.05 or P< 0.01). Conclusion: Monitoring the expression levels of AGEs and RAGE can reflect the wound-healing effect of patients with second-degree burns, and the prognosis of the wound is closely related to the expression levels of AGEs, RAGE, and scab abrasion. In the treatment of second-degree burn wounds, scab abrasion can grasp the level of necrotic scab removal, can achieve “relatively accurate” removal of necrotic tissue, maximally protect the ecological tissue between wounds and retaining normal tissue, and can play a positive role in promoting the healing process of burn wounds;at the same time, nanosilver dressings have good antibacterial properties and high safety, and mussel mucin has anti-inflammatory and antioxidant activities and the characteristics of blocking nerve endings, which can effectively relieve the burning, stinging, and itching of sensitive skin and effectively promote wound healing.展开更多
Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of h...Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of high-temperature treatments has introduced uncertainties regarding the compositions and microstructures of resulting derivatives.Additionally,complete carbonization has led to diminished yields of the produced carbon composites,significantly limiting their practical applications.Consequently,the exploration of pristine MOF-based EMW absorbers presents an intriguing yet challenging endeavor,primarily due to inherently low electrical conductivity.In this study,we showcase the utilization of structurally robust Zr-MOFs as scaffolds to build highly conductive Zr-MOF/PPy composites via an inner-outer dual-modification approach,which involves the production of conducting polypyrrole(PPy)both within the confined nanoporous channels and the external surface of Zr-MOFs via post-synthetic modification.The interconnection of confined PPy and surface-lined PPy together leads to a consecutive and extensive conducting network to the maximum extent.This therefore entails outstanding conductivity up to~14.3 S cm^(-1) in Zr-MOF/PPy composites,which is approximately 1-2 orders of magnitude higher than that for conductive MOF nanocomposites constructed from either inner or outer modification.Benefiting from the strong and tunable conduction loss,as well as the induced dielectric polarization originated from the porous structures and MOF-polymer interfaces,Zr-MOF/PPy exhibits excellent microwave attenuation capabilities and a tunable absorption frequency range.Specifically,with only 15 wt.%loading,the minimum reflection loss(RLmin)can reach up to-67.4 dB,accompanied by an effective absorption bandwidth(EAB)extending to 6.74 GHz.Furthermore,the microwave absorption characteristics can be tailored from the C-band to the Ku-band by adjusting the loading of PPy.This work provides valuable insights into the fabrication of conductive MOF composites by presenting a straightforward pathway to enhance and reg-ulate electrical conduction in MOF-based nanocomposites,thus paving a way to facilely fabricate pristine MOF-based microwave absorbers.展开更多
BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gast...BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness.This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.AIM To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.METHODS A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025.This study used a stratified block randomization method,and then allocated groups using computer-generated random number sequences(SAS 9.4 software).The groups were divided into two groups:A control group of 60 patients who received routine postoperative intervention measures,and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical CONCLUSION The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective.The benefits of this approach include the promotion of postoperative gastrointestinal function,the reduction of stress response,the attainment of optimal results,and the enhancement of patient satisfaction.展开更多
基金Beijing Jishuitan Hospital Nova Program Funding[XKXX201617]。
文摘Objective The objective of this report was to demonstrate the clinical application of free flow-through anterolateral thigh flaps for the treatment of high-tension electrical wrist burns.Methods We collected the data of 8 patients with high-tension electrical wrist burns admitted to Beijing Jishuitan Hospital from January 2014 to December 2018.The clinical and pathological data were extracted from electronic hospital medical records.We obtained follow-up information through clinic visits.Results The injury sites for all 8 patients were the wrists,specifically 5 right and 3 left wrists,all of which were on the flexor side.Five patients had ulnar artery embolism necrosis and patency,with injury to the radial artery.Two patients had ulnar and radial arterial embolization and necrosis.The last patient had ulnar arterial embolization and necrosis with a normal radial artery.After debridement,the wound area ranged from 12 cm×9 cm to 25 cm×16 cm.The diagnoses for the eight patients were type II to type III high-tension electrical wrist burns.Free flow-through anterolateral thigh flaps(combined with great saphenous vein transplantation if necessary)were used to repair the wounds.The prognosis for all patients was good after six months to one year of follow-up.Conclusion Treating wrist types II and III high-tension electrical burns is still challenging in clinical practice.The use of free flow-through anterolateral thigh flaps(combined with great saphenous vein transplantation if necessary)to repair the wound and to restore the blood supply for the hand at the same time is a good choice for treating severe wrist electrical burns.
文摘AIM To look into the management options of early debridement of the wound, followed by vascularized cover to bring in fresh blood supply to remaining tissue in electrical burns. METHODS A total of 16 consecutive patients sustaining full thickness forearm burns over a period of one year were included in the study group. Debridement was undertaken within 48 h in 13 patients. Three patients were taken for debridement after 48 h. Debridement was repeated within 2-4 d after daily wound assessment and need for further debridement. RESULTS On an average two debridements(range 1-4) was required in our patients for the wound to be ready for definitive cover. Interval between each debridement ranged from 2-18 d. Fourteen patients were provided vascularized cover after final debridement(6 free flaps, 8 pedicled flaps). Functional assessment of gross hand function done at 6 wk, 2 mo, 3 mo and 6 mo follow-up. CONCLUSION High-tension electrical burns lead to significant morbi-dity. These injuries are best managed by early decompression followed by multiple serial debridements. The ideal timing of free flap coverage needs further investigation.
文摘BACKGROUND Electrical burns are devastating injuries and can cause deep burns with significant morbidity and delayed sequelae.Epidemiological data regarding the etiology,socioeconomic differences and geographic variation are necessary to assess the disease burden and plan an effective preventive strategy.These severe injuries often lead to amputations and thus hamper quality of life in the long term AIM To identify the population at maximum risk of sustaining electrical burns.We also studied the impact of electrical burns on these patients in terms of quality of life as well as return to work.METHODS The study was conducted at a tertiary referral teaching hospital over a period of eighteen months.All patients with a history of sustaining electrical burns and satisfying the inclusion criteria were included in the study.All relevant epidemiological parameters and treatment details were recorded.The patients were subsequently followed up at 3 mo,6 mo and 9 mo.The standardized Brief Version of the Burn Specic Health Scale(BSHS-B)was adopted to assess quality of life.Statistical analysis was conducted using IBM SPSS statistics(version 22.0).A P value of<0.05 was considered statistically significant.RESULTS A total of 103 patients were included in the study.The mean age of the patients was 31.83 years(range 18-75 years).A significant majority(91.3%)of patients were male.The mean total body surface area(TBSA)in these patients was 21.1%.In most of the patients(67%),the injury was occupation-related.High voltage injuries were implicated in 72.8%of patients.Among the 75 high voltage burn patients,31(41%)required amputation.The mean number of surgeries the patients underwent in hospital was 2.03(range 1 to 4).The quality of life parameters amongst the patients sustaining high voltage electrical burns were poorer when compared to low voltage injuries at all follow-up intervals across nine domains.In eight of these domains,the difference was statistically significant.Similarly,the scores among the amputees were poorer when compared to non-amputees.The difference was statistically significant in six domains.CONCLUSION Electrical burns remain a problem in the developing world.Most injuries are occupation-related.The quality of life in patients with high voltage burns and amputees remains poor.Work resumption was almost impossible for amputees.These patients could not regain pre-injury status.Steps should be taken to create awareness and to implement an effective preventive strategy to safeguard against electrical injuries.
文摘We reported a case of a 30-year-old man who reportedly sustained electrical burns and fell from a high voltage electric pole about 50 meter high onto a metal that caused impalement injury.In addition,he sustained full-thickness burns of the right upper limb(7%),the right hemithorax,the perineum(sparing the penis),the anterior abdominal wall and the lateral aspect of both thighs.There was 43%burned surface area in total.Radiographic examination revealed a slender curved object extending from his perineum into the pelvis.The management of this case was a challenging one which was described in this article.
基金Supported by the National Natural Science Foundation of China (50806005,50736002,61072005)
文摘This study was conducted to investigate the characteristics of meso-scale combustion.The technique of electrical capacitance tomography(ECT) was used to locate flame position and monitor the effect corresponding to varied air/fuel ratio in a meso-scale combustor.Combustion phenomena including igniting,quenching and unsteady combustion have been visualized using ECT.The method of metallization protecting ECT sensor from high temperature damage and the novel calibration method adapted to ECT monitoring of unknown permittivity flame have been shown to be successful.At the same time,electrical nature of combustion and dielectric characteristics of hy-drocarbon flame were studied.The relationship between flame permittivity and state parameters of combustion gas was demonstrated preliminarily.
文摘An arc model considering deviations from thermodynamic and chemical equilibrium has been developed in order to achieve a better understanding of the arc plasma close to material surfaces.The model is based on unified consideration of the thermionic tungsten cathode,the arc region and the flat anode made of copper.The heat transfer within the electrodes is coupled with the plasma through the energy fluxes onto the electrode boundaries.Electrical characteristics of an 8 mm long free-burning arc are presented along with findings from spectroscopic measurements of the plasma emission in atmospheric pressure argon.The arc current varied from 60 A up to 200 A,and the gas flow rate was set at 12 L/min(at atmospheric pressure,room temperature).
基金financial support from the Nuclear Energy Science&Technology and Human Resource Development Project of the Japan Atomic Energy Agency/Collaborative Laboratories for Advanced Decommissioning Science(No.R04I034)The author Ruicong Xu appreciates the scholarship(financial support)from the China Scholarship Council(CSC,No.202106380073).
文摘Laser-induced aerosols,predominantly submicron in size,pose significant environmental and health risks during the decommissioning of nuclear reactors.This study experimentally investigated the removal of laser-generated aerosol particles using a water spray system integrated with an innovative system for pre-injecting electrically charged mist in our facility.To simulate aerosol generation in reactor decommissioning,a high-power laser was used to irradiate various materials(including stainless steel,carbon steel,and concrete),generating aerosol particles that were agglomerated with injected water mist and subsequently scavenged by water spray.Experimental results demonstrate enhanced aerosol removal via aerosol-mist agglomeration,with charged mist significantly improving particle capture by increasing wettability and size.The average improvements for the stainless steel,carbon steel,and concrete were 40%,44%,and 21%,respectively.The results of experiments using charged mist with different polarities(both positive and negative)and different surface coatings reveal that the dominant polarity of aerosols varies with the irradiated materials,influenced by their crystal structure and electron emission properties.Notably,surface coatings such as ZrO_(2)and CeO_(2)were found to possibly alter aerosol charging characteristics,thereby affecting aerosol removal efficiency with charged mist configurations.The innovative aerosol-mist agglomeration approach shows promise in mitigating radiation exposure,ensuring environmental safety,and reducing contaminated water during reactor dismantling.This study contributes critical knowledge for the development of advanced aerosol management strategies for nuclear reactor decommissioning.The understanding obtained in this work is also expected to be useful for various environmental and chemical engineering applications such as gas decontamination,air purification,and pollution control.
基金supported by the Fundamental Research Funds for the Central Universities,Nos.G2021KY05107,G2021KY05101the National Natural Science Foundation of China,Nos.32071316,32211530049+1 种基金the Natural Science Foundation of Shaanxi Province,No.2022-JM482the Education and Teaching Reform Funds for the Central Universities,No.23GZ230102(all to LL and HH).
文摘Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance tomography enables real-time monitoring of changes in cerebral blood perfusion within the ischemic brain,but investigating the feasibility of using this method to assess post-stroke rehabilitation in vivo remains critical.In this study,ischemic stroke was induced in rats through middle cerebral artery occlusion surgery.Transcranial focused ultrasound stimulation was used to treat the rat model of ischemia,and electrical impedance tomography was used to measure impedance during both the acute stage of ischemia and the rehabilitation stage following the stimulation.Electrical impedance tomography results indicated that cerebral impedance increased after the onset of ischemia and decreased following transcranial focused ultrasound stimulation.Furthermore,the stimulation promoted motor function recovery,reduced cerebral infarction volume in the rat model of ischemic stroke,and induced the expression of brain-derived neurotrophic factor in the ischemic brain.Our results also revealed a significant correlation between the impedance of the ischemic brain post-intervention and improvements in behavioral scores and infarct volume.This study shows that daily administration of transcranial focused ultrasound stimulation for 20 minutes to the ischemic hemisphere 24 hours after cerebral ischemia enhanced motor recovery in a rat model of ischemia.Additionally,our findings indicate that electrical impedance tomography can serve as a valuable tool for quantitatively evaluating rehabilitation after ischemic stroke in vivo.These findings suggest the feasibility of using impedance data collected via electrical impedance tomography to clinically assess the effects of rehabilitatory interventions for patients with ischemic stroke.
基金supported by European Union Funding Programme,PNRR,No. 760058(to DMH)the UEFISCDI Project,No. PN-III-P4-IDPCE-2020-059(to APW)
文摘The major aim of stroke therapy is to stimulate brain repair and improve behavioral recovery after cerebral ischemia.One option is to stimulate endogenous neurogenesis in the subventricular zone and direct the newly formed neurons to the damaged area.However,only a small percentage of these neurons survive,and many do not reach the damaged area,possibly because the corpus callosum impedes the migration of subventricular zone-derived stem cells into the lesioned cortex.A second major obstacle to stem cell therapy is the strong inflammatory reaction induced by cerebral ischemia,whereby the associated phagocytic activity of brain macrophages removes both therapeutic cells and/or cell-based drug carriers.To address these issues,neurogenesis was electrically stimulated in the subventricular zone,followed by isolation of proliferating cells,including newly formed neurons,which were subsequently mixed with a nutritional hydrogel.This mixture was then transferred to the stroke cavity of day 14 post-stroke mice.We found that the performance of the treated animals improved in behavioral tests,including novel object,open field,hole board,grooming,and“time-to-feel”adhesive tape tests.Furthermore,immunostaining revealed that the stem cell marker nestin,the neuroepithelial marker Mash1,and the immature neuronal marker doublecortin-positive cells survived in the transplanted area for 2 weeks,possibly due to reduced phagocytic activity and supportive angiogenesis.These results clearly indicate that the transplantation of committed subventricular zone stem cells combined with a protective nutritional gel directly into the infarct cavity after the peak of stroke-induced neuroinflammation represents a feasible approach to improve neurorestoration after cerebral ischemia.
基金supported partially by grants from the National Natural Science Foundation of China(82470068,82270086,GS Zhang82372185,BP Tian)+2 种基金the Natural Science Foundation of Zhejiang Province(Key Project)(LZ25H150001,GS Zhang)the National Health Commission Scientifi c Research Fund Zhejiang Provincial Health Major Science and Technology Plan Project(co-construction project of National Health Commission Committee and Zhejiang Province)(WKJ-ZJ-2526,GS Zhang)the Medical and Health Research Program of Zhejiang Province(2023572679).
文摘Electrical impedance tomography(EIT)is a non-invasive imaging modality that generates real-time images by measuring tissue bioimpedance.It works by applying current and collecting voltage data to reconstruct images of electrical conductivity,refl ecting tissue properties.[1]We aim to off er a comprehensive guide to the fundamental technology behind EIT and to explore its clinical applications across both pulmonary and extrapulmonary domains.
基金supported by the National Key Research and Devel-opment Program of China(Grant No.2023YFD1500200)the funding project of Northeast Geological S&T Innovation Center of China Geologi-cal Survey(Grant No.QCJJ2022-9)+3 种基金the Strategic Priority Research Pro-gram of the Chinese Academy of Sciences(Grant No.XDA28060100)the Youth Interdisciplinary Team Project of the Chinese Academy of Sciences(JCTD-2021-04)the Informatization Plan of the Chinese Academy of Sciences(Grant No.CAS-WX2021PY-0109)the National Natural Science Foundation of China(Grants No.41971078,42271375,72221002,42001378).
文摘China’s endeavors to mitigate recurrent crop residue burning(CRB)and improve air quality have yielded positive results owing to recent pollution prevention policies.Nonetheless,persistent challenges remain,particularly in the Northeast China(NEC),where low temperature complicates crop residue management.Here,we examined the effects of cropping pattern adjustment on variations of CRB patterns in NEC during 2001-2021,utilizing the Moderate-resolution Imaging Spectroradiometer(MODIS)burned area dataset,the Visible Infrared Imaging Radiometer Suite(VIIRS)active fire dataset,and the high-accuracy crop planting area maps.Our results revealed an overall upward trend of 805.96 km^(2)/yr in NEC CRB from 2001 to 2021.The corn CRB area accounted for more than 50%of the total CRB area in each CRB-intensive year(2013-2021),and the increasing corn CRB generally aligns with the growing corn cultivation fields.A seasonal shift in CRB was found around 2017,with intensive CRB activities transitioning from both autumn and spring to primarily spring,particularly in the Songnen Plain and Sanjiang Plain.The changing trend of PM2.5 concentration aligned spatially with the shift.Moreover,the CRBs in spring of 2020 and 2021 were more severe than the major burning seasons in previous years,likely due to the disruptions during COVID-19 lockdowns.In certain years,the explanatory power of spring CRB on PM2.5 concentration was comparable to that of other natural factors,such as precipitation.This study underscores the critical need for sustained and region-specific strategies to tackle the challenges posed by CRBs.
文摘As a matured technique used in many fields,the distributed computer system is still a new management method for the aeronautical electrical power distribution system in our country. In this paper, a novel aircraft electrical power distribution system based on the distributed computer system is proposed. The principles, features and structure of the aircraft electrical power distribution system and the distributed computer system named electrical load management system (ELMS) are studied. The ELMS composed of four electrical load management centers (ELMCs) and two power source processors (PSPs) operates in the 1553B buses. Principles of the ELMCs and the PSPs are introduced. With the application of the distributed computer system, the aircraft electrical power distribution system is simple, adaptable and flexible.
基金supported by the Natural Science Foundation of Jiangsu Province(Grant No.BK20240123)the National Key Research and Development Program of China(Grant No.2022YFA1405900)the National Natural Science Foundation of China(Grant Nos.12274397,12274401,and 12034018)。
文摘The excellent mechanical properties make graphene promising for realizing nanomechanical resonators with high resonant frequencies,large quality factors,strong nonlinearities,and the capability to efectively interface with various physical systems.Equipped with gate electrodes,it has been demonstrated that these exceptional device properties can be electrically manipulated,leading to a variety of nanomechanical/acoustic applications.Here,we review the recent progress of graphene nanomechanical resonators with a focus on their electrical tunability.First,we provide an overview of diferent graphene nanomechanical resonators,including their device structures,fabrication methods,and measurement setups.Then,the key mechanical properties of these devices,for example,resonant frequencies,nonlinearities,dissipations,and mode coupling mechanisms,are discussed,with their behaviors upon electrical gating being highlighted.After that,various potential classical/quantum applications based on these graphene nanomechanical resonators are reviewed.Finally,we briefy discuss challenges and opportunities in this feld to ofer future prospects for the ongoing studies on graphene nanomechanical resonators.
基金Supported by Shanghai 2020“Science and Technology Innovation Action Plan”Medical Innovation Research Special Program:20Y21902800Shanghai Municipal Health Commission Shanghai Three-Year Action Plan to Further Accelerate the Development of Traditional Chinese Medicine Inheritance and Innovation:ZY(2021-2023)−0302)+1 种基金Shanghai Key Specialty(Acupuncture)Construction Project:shslczdzk04701Shanghai 2024"Science and Technology Innovation Action Plan"star cultivation(Sail special):24YF2740600.
文摘Transcutaneous electrical acupoint stimulation(TEAS)is a kind of physical therapy that use electric cur-rent through the electrodes placed on the surface of acupoints to produce clinical effects in the human body,which is characterized by less adverse reaction and convenient operation.It has been widely used in the treatment of various diseases.This review introduces six major clinical applications of TEAS,named analgesia,regulation of gastrointestinal function,improvement of reproductive function,enhancement of cognitive function,promotion of limb function recovery and relief of fatigue.Besides,TEAS has been ap-plied to the treatment of other chronic diseases such as hypertension and diabetes,achieving satisfactory clinical effects.However,two crucial challenges are encountered in the development of TEAS.One is the lack of standardization in the selection of parameters such as waveform,frequency,intensity and stimula-tion duration.The other is the limitation on the flexibility in the acupoint selection.This review analyzes key issues that need to be addressed in the current clinical application of TEAS,such as the selection of parameters and acupoints,and this review provides a certain reference value for optimizing regimens of TEAS and promoting its development and application.
基金supported by the Basic Science Program(No.2022R1A2C2009700)through the National Research Foundation of Korea(NRF)funded by the Ministry of Science and ICTthe Basic Science Research Capacity Enhancement Project(National Research Facilities and Equipment Center)through the Korea Ba-sic Science Institute funded by the Ministry of Education(No.2019R1A6C1010047)the Industrial Strategic Technology Development Program(No.20013248)through Korea Evaluation In-stitute of Industrial Technology funded by the Ministry of Trade,Industry&Energy(MOTIE,Korea).
文摘Thermally conductive papers with electrical insulation and mechanical robustness are essential for efficient thermal management in modern electronics.In this study,we introduced a metal ion-assisted interfacial crosslinking strategy to strengthen sugarfunctionalized graphene fluoride(SGF)and cellulose nanofibers(CNF)by hydrogen bonding and metal ion crosslinking that leads to simultaneous enhancements in thermal conductivity and mechanical properties.The facile sugarassisted ball-milling exfoliation method was developed to achieve the exfoliation of graphite fluoride and hydroxyl group functionalization on the surface of graphene fluoride.Thanks to the good dispersibility of the SGF sheets in water,the flexible SGF/CNF composite papers with hydrogen bonding were prepared via vacuum-assisted filtration.We introduced hydrogen bonding and metal ion crosslinking into SGF/CNF papers to obtain densely packed composite papers.Ca^(2+)or Al^(3+)ion-crosslinked SGF/CNF papers exhibited superior thermal and mechanical properties owing to hydrogen bonding and metal ion crosslinking.SGF/CNF-Ca^(2+)and SGF/CNF-Al^(3+)papers at 50 wt%of SGF yield in-plane thermal conductivities of 72.93 and 75.02 W m^(-1) K^(-1),and tensile strengths of 121.5 and 135.7 MPa,respectively.A thermal percolation value was observed at 12.6 vol%of SGF filler content.In addition,the SGF/CNF papers exhibited electrical insulation properties.These remarkable characteristics of the metal ion-crosslinked SGF/CNF papers are attributed to the densely packed structures caused by the strong interfacial interactions from hydrogen bonding as well as metal ion-crosslinking that could promote phonon transport.High-performance metal ion-crosslinked SGF/CNF papers with these fascinating advantages offer great potential for the thermal management of flexible electronics.
基金supported by the National Natural Science Foundation of China(No.22278260)the Open Foundation of Key Laboratory of Auxiliary Chemistry and Technology for Chemical Industry(No.KFKT2021-14)Shaanxi Collaborative Innovation Center of Industrial Auxiliary Chemistry and Technology(No.KFKT2021-14).
文摘Aramid papers (AP), made of aramid fibers, demonstrate superiority in electrical insulation applications. Unfortunately, the strength and electrical insulating properties of AP remain suboptimal, primarily due to the smooth surface and chemical inertness of aramid fibers. Herein, AP are modified via the nacre-mimetic structure composed of aramid nanofibers (ANF) and carbonylated basalt nanosheets (CBSNs). This is achieved by impregnating AP into an ANF-CBSNs (A-C) suspension containing a 3D ANF framework as the matrix and 2D CBSNs as fillers. The resultant biomimetic composite papers (AP/A-C composite papers) exhibit a layered “brick-and-mortar” structure, demonstrating superior mechanical and electrical insulating properties. Notably, the tensile strength and breakdown strength of AP/A-C5 composite papers reach 39.69 MPa and 22.04 kV mm^(−1), respectively, representing a 155 % and 85 % increase compared to those of the control AP. These impressive properties are accompanied with excellent volume resistivity, exceptional dielectric properties, impressive folding endurance, outstanding heat insulation, and remarkable flame retardance. The nacre-inspired strategy offers an effective approach for producing highly promising electrical insulating papers for advanced electrical equipment.
基金the National Natural Science Foundation of China(42472194,42302153,and 42002144)the Fundamental Research Funds for the Central Univer-sities(22CX06002A).
文摘Karst fractures serve as crucial seepage channels and storage spaces for carbonate natural gas reservoirs,and electrical image logs are vital data for visualizing and characterizing such fractures.However,the conventional approach of identifying fractures using electrical image logs predominantly relies on manual processes that are not only time-consuming but also highly subjective.In addition,the heterogeneity and strong dissolution tendency of karst carbonate reservoirs lead to complexity and variety in fracture geometry,which makes it difficult to accurately identify fractures.In this paper,the electrical image logs network(EILnet)da deep-learning-based intelligent semantic segmentation model with a selective attention mechanism and selective feature fusion moduledwas created to enable the intelligent identification and segmentation of different types of fractures through electrical logging images.Data from electrical image logs representing structural and induced fractures were first selected using the sliding window technique before image inpainting and data augmentation were implemented for these images to improve the generalizability of the model.Various image-processing tools,including the bilateral filter,Laplace operator,and Gaussian low-pass filter,were also applied to the electrical logging images to generate a multi-attribute dataset to help the model learn the semantic features of the fractures.The results demonstrated that the EILnet model outperforms mainstream deep-learning semantic segmentation models,such as Fully Convolutional Networks(FCN-8s),U-Net,and SegNet,for both the single-channel dataset and the multi-attribute dataset.The EILnet provided significant advantages for the single-channel dataset,and its mean intersection over union(MIoU)and pixel accuracy(PA)were 81.32%and 89.37%,respectively.In the case of the multi-attribute dataset,the identification capability of all models improved to varying degrees,with the EILnet achieving the highest MIoU and PA of 83.43%and 91.11%,respectively.Further,applying the EILnet model to various blind wells demonstrated its ability to provide reliable fracture identification,thereby indicating its promising potential applications.
文摘Objective: To evaluate the improvement effect of combined treatment of eschar abrasion, nanosilver dressing, and mussel mucin spray on wound healing in patients with second-degree burns, and to explore their effects on the expression level of (advanced glycation end products) AGEs in wound tissue, so as to provide a basis for the application of AGEs expression level in wound tissue in the future clinical treatment of second-degree burns. Methods: Patients with second-degree burns admitted to the Department of Burns and Plastic Surgery of the Second Affiliated Hospital of Shantou University Medical College from July 2023 to July 2024 were selected as the research subjects. This study was a non-double-blind study, and both patients and researchers were aware of the treatment methods. They were randomly divided into Group A (control group) and Group B (study group). According to the order of their visits, the patients were numbered in advance;then the seed number was taken, and 70 random numbers were generated on the computer using SAS, the first 35 corresponding to group A, and the last 35 corresponding to group B;the random numbers were arranged from small to large, and the rank of the random numbers was the patient number;finally, the patient numbers were arranged from small to large, and the corresponding groups were the grouping scheme. 1) Wound healing time: The wound healing was observed every day, and the wound healing time was calculated when the wound was completely epithelialized. 2) Wound healing: The wound healing area was measured 1, 7, and 14 days after treatment, and transparent paper was used to record combined with a computer-assisted imaging system. Wound healing rate = wound healing area (cm2)/total wound area before treatment (cm2) × 100%. The time for complete wound healing was recorded in the two groups of patients. 3) Pain: The pain was evaluated at 1, 7, and 14 days after treatment using the visual analogue scale (VAS). The higher the score, the more severe the pain. 4) Scar condition: Scar formation was evaluated 1, 3, and 6 months after wound healing using the VAS scale, with a total score of 15 points. The higher the score, the more severe the scar. 5) Detect the expression of AGEs in wound tissue. Results: The wound healed 14.03 ± 2.28 days after eschar removal, with a cure rate of 97.8%. No infection occurred in the wound after eschar removal in all patients. The wound healing time ranged from 9 to 23 days, with an average healing time of 28.41 ± 1.45 days. The healing quality was satisfactory. The Vancouver Scar Scale scored the wound healing scar as 0.81 ± 0.73 points. Western blot was used to detect the expression of AGEs, (receptor for advanced glycation end products) RAGE, and protein in the wound tissue. Results After 7, 14, and 28 days of medication, the wounds of diabetic patients healed well. The drug treatment efficacy and hydroxyproline content showed an upward trend, and the expression levels of AGEs, RAGE, and HIF-1a proteins showed a downward trend. Compared with day 0, the hydroxyproline content of the wound granulation tissue on days 7, 14, and 28 was significantly increased (P< 0.01), and the expression levels of AGEs, RAGE, and HIF-1α proteins were significantly downregulated (P< 0.05 or P< 0.01). Conclusion: Monitoring the expression levels of AGEs and RAGE can reflect the wound-healing effect of patients with second-degree burns, and the prognosis of the wound is closely related to the expression levels of AGEs, RAGE, and scab abrasion. In the treatment of second-degree burn wounds, scab abrasion can grasp the level of necrotic scab removal, can achieve “relatively accurate” removal of necrotic tissue, maximally protect the ecological tissue between wounds and retaining normal tissue, and can play a positive role in promoting the healing process of burn wounds;at the same time, nanosilver dressings have good antibacterial properties and high safety, and mussel mucin has anti-inflammatory and antioxidant activities and the characteristics of blocking nerve endings, which can effectively relieve the burning, stinging, and itching of sensitive skin and effectively promote wound healing.
基金supported by the Fundamental Research Funds for the Central Universities(Nos.2232023D-01 and 2232023D-07)the Shanghai Science&Technology Committee(No.22ZR1403300)the National Natural Science Foundation of China(No.52372040).
文摘Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of high-temperature treatments has introduced uncertainties regarding the compositions and microstructures of resulting derivatives.Additionally,complete carbonization has led to diminished yields of the produced carbon composites,significantly limiting their practical applications.Consequently,the exploration of pristine MOF-based EMW absorbers presents an intriguing yet challenging endeavor,primarily due to inherently low electrical conductivity.In this study,we showcase the utilization of structurally robust Zr-MOFs as scaffolds to build highly conductive Zr-MOF/PPy composites via an inner-outer dual-modification approach,which involves the production of conducting polypyrrole(PPy)both within the confined nanoporous channels and the external surface of Zr-MOFs via post-synthetic modification.The interconnection of confined PPy and surface-lined PPy together leads to a consecutive and extensive conducting network to the maximum extent.This therefore entails outstanding conductivity up to~14.3 S cm^(-1) in Zr-MOF/PPy composites,which is approximately 1-2 orders of magnitude higher than that for conductive MOF nanocomposites constructed from either inner or outer modification.Benefiting from the strong and tunable conduction loss,as well as the induced dielectric polarization originated from the porous structures and MOF-polymer interfaces,Zr-MOF/PPy exhibits excellent microwave attenuation capabilities and a tunable absorption frequency range.Specifically,with only 15 wt.%loading,the minimum reflection loss(RLmin)can reach up to-67.4 dB,accompanied by an effective absorption bandwidth(EAB)extending to 6.74 GHz.Furthermore,the microwave absorption characteristics can be tailored from the C-band to the Ku-band by adjusting the loading of PPy.This work provides valuable insights into the fabrication of conductive MOF composites by presenting a straightforward pathway to enhance and reg-ulate electrical conduction in MOF-based nanocomposites,thus paving a way to facilely fabricate pristine MOF-based microwave absorbers.
基金Supported by Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project,No.2023ZL230。
文摘BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness.This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.AIM To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.METHODS A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025.This study used a stratified block randomization method,and then allocated groups using computer-generated random number sequences(SAS 9.4 software).The groups were divided into two groups:A control group of 60 patients who received routine postoperative intervention measures,and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical CONCLUSION The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective.The benefits of this approach include the promotion of postoperative gastrointestinal function,the reduction of stress response,the attainment of optimal results,and the enhancement of patient satisfaction.
