The activities of 7-ethoxyresorufin-O-deetylase （EROD）, 7-benzyloxyresorufin-O-debenzylase （BROD）, 7-pentoxyresorufin-O-depentilase （PROD）, and glutathione S-transferase （GST） were measured in Nile tilapias ex...The activities of 7-ethoxyresorufin-O-deetylase （EROD）, 7-benzyloxyresorufin-O-debenzylase （BROD）, 7-pentoxyresorufin-O-depentilase （PROD）, and glutathione S-transferase （GST） were measured in Nile tilapias exposed for 7 days of 5 and 15μg/L 17 β-estradiol. EROD and GST activities were unchanged. PROD activity increased in animals exposed to the higher dose of the hormone, while BROD was increased after 7 exposure days to both doses of the compound. These results indicate the usefulness of these enzymes as biomarkers for 17 β-estradiol exposure.展开更多
文摘The activities of 7-ethoxyresorufin-O-deetylase （EROD）, 7-benzyloxyresorufin-O-debenzylase （BROD）, 7-pentoxyresorufin-O-depentilase （PROD）, and glutathione S-transferase （GST） were measured in Nile tilapias exposed for 7 days of 5 and 15μg/L 17 β-estradiol. EROD and GST activities were unchanged. PROD activity increased in animals exposed to the higher dose of the hormone, while BROD was increased after 7 exposure days to both doses of the compound. These results indicate the usefulness of these enzymes as biomarkers for 17 β-estradiol exposure.
