Background:Obstructed defecation syndrome(ODS)is a condition that is frequently caused by rectocele and rectal intussusception.This study aimed to evaluate the effectiveness of a modified Bresler procedure for the tre...Background:Obstructed defecation syndrome(ODS)is a condition that is frequently caused by rectocele and rectal intussusception.This study aimed to evaluate the effectiveness of a modified Bresler procedure for the treatment of ODS.The outcomes of this modified procedure were compared with the stapled transanal rectal resection(STARR)procedure.Methods:We performed a retrospective analysis of the clinical data from 76 female patients who presented with ODS between June 2014 and June 2016.The patients were divided into two treatment groups,namely Modified and STARR.Patients in the Modified group(n=36)underwent the modified Bresler procedure,which involved posterior rectal-wall resection using a circular tubular stapler with multilevel purse-string sutures.Patients in the STARR group(n=40)underwent the standard STARR procedure.We analysed post-operative complications,Wexner constipation scores(WCS),rectocele depths,and four-point post-operative satisfaction scales.Results:Patients in the Modified group exhibited shorter operative times and fewer post-operative complications(both P<0.05).At 12 months post-operatively,both the Modified and STARR groups displayed a significant improvement in the Wexner constipation score and the depth of rectocele.The post-operative WCS for the Modified group were significantly improved compared to those for the STARR group(P<0.05),while there was no significant difference in the rectocele depth between the two groups(P>0.05).Post-operative interviews at post-operative 12 months showed that patients in the Modified group had a better satisfaction(P=0.05).Conclusions:Our modified procedure may be an effective treatment strategy for patients experiencing ODS caused by rectocele and rectal intussusception,with fewer complications and effective relief of symptoms.展开更多
为研究不同冻融循环次数加载下混凝土的力学性能,利用大型多功能液压伺服三轴仪对双向应力状态下不同冻融次数(0、20、40次)和不同侧压力(0、0.06 f c、0.12 f c、0.18 f c、0.24 f c)的混凝土进行了静态(应变速率10-5/s)压缩试验,建立...为研究不同冻融循环次数加载下混凝土的力学性能,利用大型多功能液压伺服三轴仪对双向应力状态下不同冻融次数(0、20、40次)和不同侧压力(0、0.06 f c、0.12 f c、0.18 f c、0.24 f c)的混凝土进行了静态(应变速率10-5/s)压缩试验,建立了基于Ottosen准则、Bresler-Pister准则以及Kupfer-Gerstle准则的混凝土冻融双轴受压破坏模型。通过分析发现,基于Ottosen准则、Bresler-Pister准则和Kupfer-Gerstle准则所建模型均能很好地反映侧压力在0~0.24 f c范围内的混凝土双轴受压破坏规律,基于改进Kupfer-Gerstle准则建立的混凝土冻融受压破坏模型计算精度更高,且适用于单轴和双轴受压破坏的模拟。展开更多
基金supported by the National Natural Science Foundation of China[Grant No.81672364].
文摘Background:Obstructed defecation syndrome(ODS)is a condition that is frequently caused by rectocele and rectal intussusception.This study aimed to evaluate the effectiveness of a modified Bresler procedure for the treatment of ODS.The outcomes of this modified procedure were compared with the stapled transanal rectal resection(STARR)procedure.Methods:We performed a retrospective analysis of the clinical data from 76 female patients who presented with ODS between June 2014 and June 2016.The patients were divided into two treatment groups,namely Modified and STARR.Patients in the Modified group(n=36)underwent the modified Bresler procedure,which involved posterior rectal-wall resection using a circular tubular stapler with multilevel purse-string sutures.Patients in the STARR group(n=40)underwent the standard STARR procedure.We analysed post-operative complications,Wexner constipation scores(WCS),rectocele depths,and four-point post-operative satisfaction scales.Results:Patients in the Modified group exhibited shorter operative times and fewer post-operative complications(both P<0.05).At 12 months post-operatively,both the Modified and STARR groups displayed a significant improvement in the Wexner constipation score and the depth of rectocele.The post-operative WCS for the Modified group were significantly improved compared to those for the STARR group(P<0.05),while there was no significant difference in the rectocele depth between the two groups(P>0.05).Post-operative interviews at post-operative 12 months showed that patients in the Modified group had a better satisfaction(P=0.05).Conclusions:Our modified procedure may be an effective treatment strategy for patients experiencing ODS caused by rectocele and rectal intussusception,with fewer complications and effective relief of symptoms.
文摘为研究不同冻融循环次数加载下混凝土的力学性能,利用大型多功能液压伺服三轴仪对双向应力状态下不同冻融次数(0、20、40次)和不同侧压力(0、0.06 f c、0.12 f c、0.18 f c、0.24 f c)的混凝土进行了静态(应变速率10-5/s)压缩试验,建立了基于Ottosen准则、Bresler-Pister准则以及Kupfer-Gerstle准则的混凝土冻融双轴受压破坏模型。通过分析发现,基于Ottosen准则、Bresler-Pister准则和Kupfer-Gerstle准则所建模型均能很好地反映侧压力在0~0.24 f c范围内的混凝土双轴受压破坏规律,基于改进Kupfer-Gerstle准则建立的混凝土冻融受压破坏模型计算精度更高,且适用于单轴和双轴受压破坏的模拟。