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An AAS Dependent Method for Quantitative Analysis of Essential Trace Elements from Blood Samples of Pakistani Female Breast Cancer Patients 被引量:1
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作者 Ghulam Qadir Chanihoon Ahsanullah Unar +6 位作者 Ayaz Ali Memon Tassadaq Hussain Jafar Huma I. Shaikh Ayesha Sani Raj Kumar Sanam Erum Soomro Muqaddas Qureshi 《Advances in Breast Cancer Research》 2021年第3期44-59,共16页
Breast cancer is the second leading cancer in the world. <span style="font-family:Verdana;">The long-term</span><span style="font-family:Verdana;"> exposure </span><span ... Breast cancer is the second leading cancer in the world. <span style="font-family:Verdana;">The long-term</span><span style="font-family:Verdana;"> exposure </span><span style="font-family:Verdana;">of</span><span style="font-family:Verdana;"> some metallic compounds induces different forms of cancer, including breast cancer. Trace elements are essential metals for the physiological functions of the cell on a molecular level and also contribute </span><span style="font-family:Verdana;">in</span> <span style="font-family:Verdana;">treatment</span><span style="font-family:Verdana;"> of many diseases. </span><span style="font-family:Verdana;">The aim of study was</span><span style="font-family:Verdana;"> to compare the level of essential trace elements, sodium, potassium, calcium, iron, and zinc in breast cancer patients with normal healthy adult women. Total forty-five patients (age range from 25</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">73 years) were included in this study and divided into three groups according to three different stages of breast cancer including tumor-II, tumor-III </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> tumor-IV. Blood was collected from all participants after taking history, clinical data </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> taking consent. However, about fifteen non-cancer healthy women in </span><span style="font-family:Verdana;">age</span><span style="font-family:Verdana;"> range from 26</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">69 years were subjected to this study. The elemental concentrations were determined through atomic absorption spectrophotometer </span><span style="font-family:Verdana;">subsequent to</span><span style="font-family:Verdana;"> microwave-induced acid digestion. The results of Na, K, Zn, Fe, Ca, were observed </span></span><span style="font-family:Verdana;">to </span><span style="font-family:Verdana;">decrease in blood samples of breast cancer patients as compared to non-cancer subjects. The results are reliable with other numerous literature reported studies, the efficiency, and deficiency of these trace metals may contribute </span><span style="font-family:Verdana;">an </span><span style="font-family:Verdana;">important</span><span style="font-family:Verdana;"> role in the progress of breast cancer.</span> 展开更多
关键词 breast cancer blood samples Invasive Ductal Carcinoma Tumor Stages Essential Elements FAAS
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