Background and Objective Treatment strategy for unstable angina has underwent significant changes since the introduction of Braunwald classification of unstable angina nearly 30 years ago,yet re-evaluation of this rou...Background and Objective Treatment strategy for unstable angina has underwent significant changes since the introduction of Braunwald classification of unstable angina nearly 30 years ago,yet re-evaluation of this routinely used classification system is rarely published in recent years.We aim to re-evaluate the Braunwald unstable angina(UA)classification on its predictive value of clinical characteristics,angiographic features,and occurrence of future adverse events.展开更多
Objective:To seek the relation between clinical presentation(Braunwaldclassification)or electrocardiogram(ECG)and angiographic morphology inpatients with unstable angma(UA),and to determine which clitoral markerscould...Objective:To seek the relation between clinical presentation(Braunwaldclassification)or electrocardiogram(ECG)and angiographic morphology inpatients with unstable angma(UA),and to determine which clitoral markerscould reliably predict unstable lesions and cardiac eventsMethods:120 hospdalized patients with a clinical diagnosis of UA and anabonrmal angiograms(≥50% diameter stenosis)were selected The lesionmorphology included sunple lesion,complex lesion and inracoronarythrombus(ICT)In-hospital events included acute myocardialinfarction,cardiac death and prompt revasculan-zation Logistic regressionwas used to evaluate the ability of clinical markers to predict unstable lesionsand cardiac events.Results:There were more complex lesion in class Ⅲ group(61%,or 20 of33)than in class 1 group(30%,or 13 of 43,P【0.05)and more ICT in class Ⅲgroup(18%.or 6 of 33)than in class Ⅱ group(2%,or 1 of 44,P【0.05)Thetare of cardiac events was higher m class Ⅲ patients(58%,or 19 of 33)thanin class 1 patients(19%,or 8 of 43,P=0.01)or in class Ⅱ patients(25%,or Ⅱof 44,P【0.01)Logistic regrassion analysis demonstrated that an abnormalST segment of ECG or Braunwald class Ⅲ were highly predictive of thepresence of complex lesion morphology(P【0.01,OR 4.9,P【001,OR3.3,respectively)An abnormal ECG was the single predictive clintcalindicator of triple coronary disease(P【0.01.OR 3.9)and cardiacevents(P【0.001,OR 4.8).Conclusion:Complex lesion can be best identified by the clinical featureof recent onset refractory angina at rest and abnormal ECG Patients withabnormal ST segment represents a high rate of triple coronary disease anda high risk of cardiac events.展开更多
文摘Background and Objective Treatment strategy for unstable angina has underwent significant changes since the introduction of Braunwald classification of unstable angina nearly 30 years ago,yet re-evaluation of this routinely used classification system is rarely published in recent years.We aim to re-evaluate the Braunwald unstable angina(UA)classification on its predictive value of clinical characteristics,angiographic features,and occurrence of future adverse events.
文摘Objective:To seek the relation between clinical presentation(Braunwaldclassification)or electrocardiogram(ECG)and angiographic morphology inpatients with unstable angma(UA),and to determine which clitoral markerscould reliably predict unstable lesions and cardiac eventsMethods:120 hospdalized patients with a clinical diagnosis of UA and anabonrmal angiograms(≥50% diameter stenosis)were selected The lesionmorphology included sunple lesion,complex lesion and inracoronarythrombus(ICT)In-hospital events included acute myocardialinfarction,cardiac death and prompt revasculan-zation Logistic regressionwas used to evaluate the ability of clinical markers to predict unstable lesionsand cardiac events.Results:There were more complex lesion in class Ⅲ group(61%,or 20 of33)than in class 1 group(30%,or 13 of 43,P【0.05)and more ICT in class Ⅲgroup(18%.or 6 of 33)than in class Ⅱ group(2%,or 1 of 44,P【0.05)Thetare of cardiac events was higher m class Ⅲ patients(58%,or 19 of 33)thanin class 1 patients(19%,or 8 of 43,P=0.01)or in class Ⅱ patients(25%,or Ⅱof 44,P【0.01)Logistic regrassion analysis demonstrated that an abnormalST segment of ECG or Braunwald class Ⅲ were highly predictive of thepresence of complex lesion morphology(P【0.01,OR 4.9,P【001,OR3.3,respectively)An abnormal ECG was the single predictive clintcalindicator of triple coronary disease(P【0.01.OR 3.9)and cardiacevents(P【0.001,OR 4.8).Conclusion:Complex lesion can be best identified by the clinical featureof recent onset refractory angina at rest and abnormal ECG Patients withabnormal ST segment represents a high rate of triple coronary disease anda high risk of cardiac events.
