From the ethanol extract of the roots of Brachystemma calycinum D. Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1 - 4) have been isolated. Their structures were establish...From the ethanol extract of the roots of Brachystemma calycinum D. Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1 - 4) have been isolated. Their structures were established as cyclo (Pro(1)-Phe-Leu-Ala(1)-Thr-Pro(2)-Ala(2)-Gly) (1), cyclo (Pro(1)-Ala-Phe-Trp-Asp-Pro(2)-Leu-Gly) (2), cyclo (Pro(1)-Ile-Gly-Pro(2)-Val-Ala(1)-Ala(2)-Tyr) (3) and cyclo ( Pro-OMet-Trp-Ile-Gly-Ala-Leu-Asp) (4) respectively by means of extensive spectral methods.展开更多
Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild c...Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild cultivar and market demand and status of Brachystemma calycinum were systematically studied, so as to provide a basis for resource development and utilization.展开更多
文摘From the ethanol extract of the roots of Brachystemma calycinum D. Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1 - 4) have been isolated. Their structures were established as cyclo (Pro(1)-Phe-Leu-Ala(1)-Thr-Pro(2)-Ala(2)-Gly) (1), cyclo (Pro(1)-Ala-Phe-Trp-Asp-Pro(2)-Leu-Gly) (2), cyclo (Pro(1)-Ile-Gly-Pro(2)-Val-Ala(1)-Ala(2)-Tyr) (3) and cyclo ( Pro-OMet-Trp-Ile-Gly-Ala-Leu-Asp) (4) respectively by means of extensive spectral methods.
基金Supported by the Special Fund for Major Research Program of Guangxi Province(GKZ1298001-1-8)Medical Treatment and Public Health Research and Development Project of Guangxi Province(S201416-02)~~
文摘Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild cultivar and market demand and status of Brachystemma calycinum were systematically studied, so as to provide a basis for resource development and utilization.
