We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living...We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living corporeality） within the framework of Enrique Dussel＇s Latin American Political Philosophy. We are interested in these theoretical approaches （Foucault＇s biopolitics and Dussel＇s Liberation Politics） given the political implications and prominence they grant to the notions of body and life in contemporary societies. The works we are interested in to contrast present different standpoints： In the first one, life is related to the exercise of political power, whereas in the second one its approach concentrates on political emancipation processes. We believe, however, that it is possible to find convergence points between them that allow us to explain, to a certain extent, the importance of the notion of life in contemporary societies. For this purpose, we will carry out an analysis of the notion of ＂counter behaviors,＂ a concept that Foucault briefly develops to explain how life has not been thoroughly integrated to technologies that dominate or run it but instead escape them ceaselessly.展开更多
Overweight and obesity has been a major public health problem globally.It was estimated that more than 2.1 billion adults were affected by overweight or obese in 2021 worldwide,about one fifth of whom lived in China^(...Overweight and obesity has been a major public health problem globally.It was estimated that more than 2.1 billion adults were affected by overweight or obese in 2021 worldwide,about one fifth of whom lived in China^([1]).By 2050,the country is forecast to remain the one with the largest population of overweight and obese globally^([1]),if no effective strategies were applied on overweight/obesity control.展开更多
Electron–hole(e–h)recombination is a fundamental process that governs energy dissipation and device efficiency in semiconductors.In two-dimensional(2D)materials,the formation of tightly bound excitons makes exciton-...Electron–hole(e–h)recombination is a fundamental process that governs energy dissipation and device efficiency in semiconductors.In two-dimensional(2D)materials,the formation of tightly bound excitons makes exciton-mediated e–h recombination the dominant decay pathway.In this work,nonradiative e–h recombination within excitons in monolayer MoS2 is investigated using first-principles simulations that combine nonadiabatic molecular dynamics with𝐺𝑊and real-time Bethe–Salpeter equation(BSE)propagation.A two-step process is identified:rapid intervalley redistribution induced by exchange interaction,followed by slower phonon-assisted recombination facilitated by exciton binding.By selectively removing the screened Coulomb and exchange terms from the BSE Hamiltonian,their respective contributions are disentangled—exchange interaction is found to increase the number of accessible recombination pathways,while binding reduces the excitation energy and enhances nonradiative decay.A reduction in recombination lifetime by over an order of magnitude is observed due to the excitonic many-body effects.These findings provide microscopic insights for understanding and tuning exciton lifetimes in 2D transition-metal dichalcogenides.展开更多
Objective Previous studies link lower body mass index(BMI)with increased obsessive-compulsive disorder(OCD)risk,yet other body mass indicators may be more etioloically relevant.We dissected the causal association betw...Objective Previous studies link lower body mass index(BMI)with increased obsessive-compulsive disorder(OCD)risk,yet other body mass indicators may be more etioloically relevant.We dissected the causal association between body fat mass(FM)and OCD.Methods Summary statistics from genome-wide association studies of European ancestry were utilized to conduct two-sample Mendelian randomization analysis.Heterogeneity,horizontal pleiotropy,and sensitivity analyses were performed to assess the robustness.Results The inverse variance weighting method demonstrated that a genetically predicted decrease in FM was causally associated with an increased OCD risk[odds ratio(OR)=0.680,95%confidence interval(CI):0.528–0.875,P=0.003].Similar estimates were obtained using the weighted median approach(OR=0.633,95%CI:0.438–0.915,P=0.015).Each standard deviation increases in genetically predicted body fat percentage corresponded to a reduced OCD risk(OR=0.638,95%CI:0.455–0.896,P=0.009).The sensitivity analysis confirmed the robustness of these findings with no outlier instrument variables identified.Conclusion The negative causal association between FM and the risk of OCD suggests that the prevention or treatment of mental disorders should include not only the control of BMI but also fat distribution and body composition.展开更多
Objective The rising prevalence of childhood obesity is closely associated with suboptimal dietary patterns.To address this public health concern,we conducted a comprehensive study to examine the association between c...Objective The rising prevalence of childhood obesity is closely associated with suboptimal dietary patterns.To address this public health concern,we conducted a comprehensive study to examine the association between coarse cereals consumption and body fat percentage(BFP)in Chinese children and adolescents.Methods The study included 48,305 children aged 6–17 years from 28 districts/counties in 14 provinces across seven regions of China(24,152 girls and 24,153 boys).BFP was examined using bioelectrical impedance analysis in the early morning.Coarse cereals consumption was assessed using a Food Frequency Questionnaire and categorized into three groups:0 g/1,000 kcal per day,0–10 g/1,000kcal per day,and>10 g/1,000 kcal per day(daily consumption of coarse cereals×1,000/total energy consumption).Quantile regression model was used to analyze the association between coarse cereals and BFP,adjusting for potential confounders such as age,pubertal development stage,urban/rural and regional factors,total daily dietary energy consumption,sedentary time,moderate-to-high physical activity,household income,parental education,and consumption of other foods.Results Boys aged 6–10,11–14,and 15–17 years had median daily coarse cereals consumptions of6.6 g,7.1 g,and 5.7 g,with BFP of 19.6%,19.5%,and 17.5%(all P<0.05).Girls in the same age groups showed consumption of 7.1 g,8.4 g,and 6.7 g,with BFP of 20.3%,26.4%,and 31.0%(all P<0.05).The quantile regression results for boys showed that daily consumption of coarse cereals was significantly correlated with their BFP in the 0.15,0.25,and 0.50 quartiles,with regression coefficients of-0.257,-0.221,and-0.330,respectively,after adjusting for potential confounders(P<0.05).For girls,there was a significant correlation with PBF at the 0.05,0.15,0.25,0.50,0.75,and 0.85 quartiles,with regression coefficients of-0.258,-0.366,-0.372,-0.431,-0.472,and-0.503(P<0.05 for all).Conclusions Coarse cereals consumption among Chinese children and adolescents remains relatively low.Higher consumption was inversely associated with BFP in children aged 6–17 years.Future interventional studies should assess how increased coarse cereals consumption prevents childhood obesity.展开更多
Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development pro...Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development process of the MBC App involved:1)establishing a research group;2)determining of the content of the MBC App based on Mindfulness-Based Cognitive Therapy and 3)technical exploitation and maintenance.A mixed-methods study was conducted.We selected ten BCSs by a convenience sampling method.After using the APP for three months,five assessed the quality using the Mobile App Rating Scale:User Version(uMARS)and another five were interviewed for process evaluation.Results The MBC App was developed with three modules:1)Library to provide health education information on body image,stigma,mindfulness,recovery and etc;2)Mindfulness Yoga to offer 12 Hatha yoga videos for daily practice;and 3)Mindfulness Practices to have 12 sessions of mindfulness videoconferences.Based on the uMARS data,the MBC App received high ratings for functionality(4.10±0.34),aesthetics(3.93±0.55),information quality(4.10±0.72),and perceived impact(4.03±0.96),as well as moderate ratings for engagement(3.72±0.94)and subjective quality(3.87±0.77).Participants indicated that the MBC App provided reliable knowledge,information,and emotional support.Recommendations from participants included categorizing knowledge in the Library Module,recording videoconferences of mindfulness practice,and adding discussion sessions in the videoconference.Afterward,we optimized the MBC App to enhance the user experience accordingly.Conclusions The MBC App offers online mindfulness interventions specifically for BCSs in China.The preliminary quality assessment indicates that the MBC App may be a promising tool for delivering mindfulness interventions to BCSs.展开更多
BACKGROUND Acute liver failure(ALF)is a life-threatening multisystemic condition with high short-term mortality.With the growing prevalence of obesity and metabolic syndrome,it is important to investigate the clinical...BACKGROUND Acute liver failure(ALF)is a life-threatening multisystemic condition with high short-term mortality.With the growing prevalence of obesity and metabolic syndrome,it is important to investigate the clinical implications of high body mass index(BMI)on survival outcomes in ALF.AIM To explore the impact of overweight and obesity on the clinical outcomes of patients with ALF.METHODS A retrospective observational cohort study was conducted involving patients with ALF admitted to the Johns Hopkins Health System between January 1,2000 and May 1,2020.We performed Cox proportional hazards regression to identify outcomes,including the need for liver transplantation(LT)or all-cause mortality.RESULTS A total of 196 patients were included,the median age was 43.5 years,63.3%were female,and 59.7%were of Caucasian ethnicity.Acetaminophen-induced ALF was the most common etiology(45%).The mean BMI was significantly greater among patients who underwent LT or died(29.64 kg/m^(2)vs 26.59 kg/m^(2),P=0.008)than among survivors.Patients with overweight and obesity had a higher risk of all-cause mortality or need for LT by 2.22-fold(95%CI:1.30-3.78)and 2.04-fold(95%CI:1.29-3.39),respectively.Elevated BMI was associated with renal failure and higher grades of hepatic encephalopathy.Derangements in serologic markers,including alanine transaminase,lactate,and ammonia,were associated with a mortality risk or need for LT.CONCLUSION In this large,retrospective study,with a diverse cohort of United States patients,Overweight and obese were independently associated with an increased risk of all-cause mortality or need for LT.This work highlights the importance of closely monitoring ALF patients who are overweight or obese for adverse complications and measures to improve outcomes in this vulnerable patient population.展开更多
BACKGROUND Overweight children exhibit a higher prevalence of functional gastrointestinal disorders compared with their normal-weight peers,yet the underlying reasons remain unclear.Gastrointestinal motility,a key pat...BACKGROUND Overweight children exhibit a higher prevalence of functional gastrointestinal disorders compared with their normal-weight peers,yet the underlying reasons remain unclear.Gastrointestinal motility,a key pathophysiological factor in functional gastrointestinal disorders,may be influenced by body mass index(BMI).AIM To evaluate the impact of BMI on gastric motility parameters in children with functional abdominal pain disorders(FAPDs).METHODS We assessed gastric motility in 176 children with FAPDs(61.4%females,mean age 7.94 years,SD 1.96 years)and 63 healthy controls(57.1%females,mean age 9.17 years,SD 1.90 years)at the Gastroenterology Research Laboratory,University of Kelaniya,Sri Lanka.FAPDs were diagnosed and subtyped using the Rome IV criteria:Functional abdominal pain 97 patients;irritable bowel syndrome 39 patients,functional dyspepsia(FD)25 patients;and abdominal migraine 15 patients.Gastric motility was measured using a validated ultrasound method.Weight and height were measured using sensitive standard scales.RESULTS The BMIs of children with FAPDs and controls were 15.04 and 15.46 kg/m^(2),respectively(P=0.33).Fasting antral area(FAA)and antral area at 1 min(AA1)and 15 min(AA15)were significantly greater in patients with FAPD with a higher BMI(2.71 cm^(2),12.57 cm^(2),and 7.19 cm^(2),respectively)compared with those with a lower BMI(2.12 cm^(2),10.68 cm^(2),and 6.13 cm^(2),respectively)(P<0.01).BMI positively correlated with FAA and AA15(r=0.18 and r=0.19,respectively)(P<0.01)in those with FAPDs.In controls,only AA1 was greater in the higher BMI group(12.51 cm^(2)vs 9.93 cm^(2))and had a positive correlation(r=0.33)(P≤0.01).Subgroup analysis revealed that in patients with FD,BMI negatively correlated with gastric emptying rate(GER)(r=-0.59)and antral motility index(MI)(r=-0.49),while in functional abdominal pain,MI positively correlated(r=0.25)with BMI(P≤0.01).CONCLUSION In children with FAPDs,higher BMI was associated with increased gastric antral distention during fasting and postprandial periods(as indicated by FAA,AA1,and AA15)but not with contractility and transit(MI,GER).However,in the FD subgroup,high BMI correlated with reduced GER and MI.This indicates the possible role of BMI in gastric hypomotility and the pathophysiology of FD.These findings underscore the importance of lifestyle and dietary interventions aimed at optimizing BMI in the management of FAPDs,particularly FD.展开更多
The concept of emissivity has been with the scientific and engineering world since Planck formulated his blackbody radiation law more than a century ago.Nevertheless,emissivity is an elusive concept even for ex⁃perts....The concept of emissivity has been with the scientific and engineering world since Planck formulated his blackbody radiation law more than a century ago.Nevertheless,emissivity is an elusive concept even for ex⁃perts.It is a vague and fuzzy concept for the wider community of engineers.The importance of remote sensing of temperature by measuring IR radiation has been recognized in a wide range of industrial,medical,and environ⁃mental uses.One of the major sources of errors in IR radiometry is the emissivity of the surface being measured.In real experiments,emissivity may be influenced by many factors:surface texture,spectral properties,oxida⁃tion,and aging of surfaces.While commercial blackbodies are prevalent,the much-needed grey bodies with a known emissivity,are unavailable.This study describes how to achieve a calibrated and stable emissivity with a blackbody,a perforated screen,and a reliable and linear novel IR thermal sensor,18 dubbed TMOS.The Digital TMOS is now a low-cost commercial product,it requires low power,and it has a small form factor.The method⁃ology is based on two-color measurements,with two different optical filters,with selected wavelengths conform⁃ing to the grey body definition of the use case under study.With a photochemically etched perforated screen,the effective emissivity of the screen is simply the hole density area of the surface area that emits according to the blackbody temperature radiation.The concept is illustrated with ray tracing simulations,which demonstrate the approach.Measured results are reported.展开更多
The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore how young people respond to the increasing focus on body weight management.As obesity rates climb,body weigh...The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore how young people respond to the increasing focus on body weight management.As obesity rates climb,body weight management has become a growing concern in China.The government is introducing targeted policies,hospitals are setting up dedicated clinics,and health experts are speaking out.But weight is no longer just a medical issue-it’s increas-ingly tied to identity,confidence,and social image.We examine the cultural forces shaping how young people in China and Africa approach weight-what drives their choices,how ideals are formed,and where health meets appearance in today’s shifting societies.展开更多
Background:University students face significant challenges inmaintaining healthy physical activity(PA)and dietary habits,and they often fall short of global health recommendations.Psychological factors such as social ...Background:University students face significant challenges inmaintaining healthy physical activity(PA)and dietary habits,and they often fall short of global health recommendations.Psychological factors such as social physique anxiety,body image concerns,and self-objectification may act as barriers to PA engagement,influencing both mental and physical health.The present study constructed a structural equation model(SEM)to examine the relationship between body image-related psychological factors and resistance to PA in university students from southern Spain.Methods:A cross-sectional and correlational study was conducted with 519 university students(74%females,26%males;Mean age=21.14±3.26 years)from universities in Granada and Malaga(Spain).Data were collected between May and October 2024 via online questionnaires that assessed PA engagement,Mediterranean diet adherence,eating disorder symptoms,body image-related psychological factors(social physique anxiety,appearance control beliefs,body surveillance,body shame,and self-esteem),and sociodemographic characteristics.SEM was performed to analyze relationships and sex-based differences.Results:Social physique anxietywas positively associated with body shame,body surveillance,and eating disorders,and negatively associated with self-esteem,PA engagement,and appearance control beliefs(all p<0.001).Appearance control beliefs were positively related to self-esteem,body surveillance,and PA(all p<0.05).Body surveillance was negatively linked to PA and positively linked to body shame.Mediterranean diet adherence and eating disorders were positively associated with PA(all p<0.001).Sex-based differences were observed in the model.Conclusion:Body image-related psychological factors may act as barriers to PA among university students.Interventions should integrate mental health promotion and consider sex differences.展开更多
Body mass index(BMI),with its simple formula of weight divided by height squared,has become a cornerstone tool in global public health for assessing obesity and health risks.However,as populations aging and the demand...Body mass index(BMI),with its simple formula of weight divided by height squared,has become a cornerstone tool in global public health for assessing obesity and health risks.However,as populations aging and the demand for precise health evaluation grows,the limitations of this single metric have become increasingly apparent—it fails to distinguish between muscle and adipose tissue and cannot capture the complex relationship between inflammatory status and body composition.A recent study published in Biomedical and Environmental Sciences(BES)by Zhang et al.[1],which explores the association of white blood cell(WBC)count,platelet(PLT)count,and platelet-to-white blood cell ratio(PWR)with muscle mass among Chinese communitydwelling older adults,provides critical evidence for rethinking the role of BMI.Additionally,several studies published in BES,spanning from childhood nutrition to adult metabolism,further illuminate the complexity of health assessment[2−5].Building on these findings and integrating evidence from multiple Chinese population studies,this commentary revisits the historical context,utility,inherent limitations,and future directions of this classic indicator.展开更多
BACKGROUND:This study aims to explore the causal relationship of body weight,body mass index(BMI),and waist circumference (WC) with the risk of cardiac arrest (CA) using two-sample Mendelian randomization (MR).METHODS...BACKGROUND:This study aims to explore the causal relationship of body weight,body mass index(BMI),and waist circumference (WC) with the risk of cardiac arrest (CA) using two-sample Mendelian randomization (MR).METHODS:Data were summarized using genome-wide association studies (GWAS).Twosample MR analyses were performed using the inverse variance weighting (IVW) method,the weighted median method,and the MR-Egger analysis.Heterogeneity test and sensitivity analysis were performed using Cochran’s Q test and the leave-one-out method,respectively.The Steiger test was used to detect reverse causality.Bayesian model-averaged MR was used to identify the most influential risk factors.RESULTS:A total of 13 GWAS data were collected for BMI,body weight and WC.IVW analyses showed a positive correlation of body weight,BMI,and WC with CA (all OR>1 and P<0.05),with MR-Egger and weighted median methods confirming the IVW findings.No horizontal pleiotropy or heterogeneity was observed.Sensitivity analysis indicated that no single nucleotide polymorphism(SNP) caused significant changes in overall causality.Bayesian model-averaged MR was also used to rank causality based on marginal inclusion probability (MIP),and the corresponding modelaveraged causal estimate (MACE) were confirmed,which indicated that WC (GWAS ID:ukb-b-9405)was the highest-ranked risk factor (MIP=0.119,MACE=0.011);its posterior probability was 0.057.A total of 14 sex-specific GWAS data on weight,BMI,and WC were analyzed in relationship with CA,and the MR results showed no significant effects of sex-specific factors.CONCLUSION:Body weight,BMI,and WC are causally associated with an increased risk of CA,with WC identified as the most important risk factor.展开更多
The strength of backfill body is a crucial parameter in backfilling mining,and the failure process of cemented backfill body is essentially an energy dissipation process.To investigate the effects of curing age and ce...The strength of backfill body is a crucial parameter in backfilling mining,and the failure process of cemented backfill body is essentially an energy dissipation process.To investigate the effects of curing age and cement-sand ratio on the strength and energy consumption of backfill,whole tailings were used as aggregate to prepare slurry with mass concentration of 74%,and the slurry with cement-sand ratio of 1:4,1:6,1:8 and 1:12 was poured into backfill.Uniaxial compression tests were conducted on backfill body specimens that had been cured for 7 days,14 days,28 days,and 45 days.It aims at studying the compressive strength,damage,energy storage limit,energy dissipation,and crack propagation of the fill.The results show that when the cement-sand ratio is held constant,the strength of the backfill increases with curing age.Simultaneously,when the curing age is fixed,the strength is positively correlated with the cement-sand ratio.During uniaxial compression tests,it is observed that the pre-peak energy consumption,post-peak energy consumption,total energy consumption,and unit volume strain energy of the cemented backfill body exhibit exponential relationships with both curing age and cement-sand ratio.The energy storage limit of the backfill reflects its capacity to absorb energy prior to failure,while the relationship between damage and energy consumption provides an accurate depiction of its internal failure mechanisms at different stages.In the failure process of the cemented backfill body,primary cracks accompany secondary cracks,many microcracks initiate and propagate from the stress direction,and crack propagation consumes a significant amount of energy.This study on the strength,energy storage limit,and failure of the cemented backfill body can provide valuable insights for mine safety production.展开更多
Have you ever imagined that home robots can not only help you clean,but also read you,chat and play chess with you and even take good care of you when you are sick?These are no longer scenes in science fiction movies,...Have you ever imagined that home robots can not only help you clean,but also read you,chat and play chess with you and even take good care of you when you are sick?These are no longer scenes in science fiction movies,but reality that is happening.With the rapid development of Embodied Intelligence technology,robots are evolving from“tools”to“partners”.As cold machines are given“body temperature”,an intelligent revolution has begun quietly.展开更多
The minireview titled“Modern endoscopist’s toolbox:Innovations in foreign body removal”by Shahid and published in the World Journal of Gastrointestinal Endoscopy provided a clear and comprehensive overview of endos...The minireview titled“Modern endoscopist’s toolbox:Innovations in foreign body removal”by Shahid and published in the World Journal of Gastrointestinal Endoscopy provided a clear and comprehensive overview of endoscopic management of gastrointestinal foreign bodies.It will serve as a valuable resource for endoscopists involved in the diagnosis and treatment of such cases.Several key and controversial aspects of patient management were highlighted in a meaningful way,including the importance of thorough medical history-taking,appropriate use of radiological imaging,and the selection of suitable endoscopic extraction techniques.An individualized,multidisciplinary approach is essential for diagnosis and treatment.While current guidelines offer significant support,they cannot replace the judgment of an experienced endoscopist working with a well-trained team.展开更多
Foreign body ingestion is a common gastrointestinal emergency,particularly in children,who account for 80%of cases.While most ingested objects pass spontan-eously,around 20%require medical intervention.In adults,incid...Foreign body ingestion is a common gastrointestinal emergency,particularly in children,who account for 80%of cases.While most ingested objects pass spontan-eously,around 20%require medical intervention.In adults,incidents often occur accidentally during meals,leading to impactions,especially in individuals with underlying esophageal conditions.Endoscopy remains the gold standard for foreign body retrieval,with a success rate exceeding 95%.The type,shape,and location of the foreign body determine the clinical presentation and management approach.Sharp objects,batteries,and large items pose the highest risk of complications,including perforation,obstruction,and chemical injury.Prompt endoscopic removal is guided by established protocols,with emergent inter-vention required for complete esophageal obstruction and high-risk objects.Various retrieval devices,including forceps,snares,baskets,and overtubes,are used based on the nature of the foreign body.Technological advancements,such as artificial intelligence-assisted imaging and endoscopic ultrasound,are impro-ving diagnostic precision and procedural outcomes.Despite these advances,foreign body ingestion can still lead to severe complications if not managed in a timely manner.Public awareness,preventive measures,and rapid medical res-ponse are essential in reducing morbidity and mortality associated with foreign body ingestion.展开更多
文摘We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living corporeality） within the framework of Enrique Dussel＇s Latin American Political Philosophy. We are interested in these theoretical approaches （Foucault＇s biopolitics and Dussel＇s Liberation Politics） given the political implications and prominence they grant to the notions of body and life in contemporary societies. The works we are interested in to contrast present different standpoints： In the first one, life is related to the exercise of political power, whereas in the second one its approach concentrates on political emancipation processes. We believe, however, that it is possible to find convergence points between them that allow us to explain, to a certain extent, the importance of the notion of life in contemporary societies. For this purpose, we will carry out an analysis of the notion of ＂counter behaviors,＂ a concept that Foucault briefly develops to explain how life has not been thoroughly integrated to technologies that dominate or run it but instead escape them ceaselessly.
文摘Overweight and obesity has been a major public health problem globally.It was estimated that more than 2.1 billion adults were affected by overweight or obese in 2021 worldwide,about one fifth of whom lived in China^([1]).By 2050,the country is forecast to remain the one with the largest population of overweight and obese globally^([1]),if no effective strategies were applied on overweight/obesity control.
基金supported by the National Key Research and Development Program of China (Grant Nos.2024YFA1409800 for J.Z.and2024YFA1408603 for Q.Z.)the National Natural Science Foundation of China (Grant Nos.12125408,12334004for J.Z.,and 12174363 for Q.Z.)+1 种基金the Innovation Program for Quantum Science and Technology (Grant No.2021ZD0303306 for J.Z.)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0450101 for J.Z.)。
文摘Electron–hole(e–h)recombination is a fundamental process that governs energy dissipation and device efficiency in semiconductors.In two-dimensional(2D)materials,the formation of tightly bound excitons makes exciton-mediated e–h recombination the dominant decay pathway.In this work,nonradiative e–h recombination within excitons in monolayer MoS2 is investigated using first-principles simulations that combine nonadiabatic molecular dynamics with𝐺𝑊and real-time Bethe–Salpeter equation(BSE)propagation.A two-step process is identified:rapid intervalley redistribution induced by exchange interaction,followed by slower phonon-assisted recombination facilitated by exciton binding.By selectively removing the screened Coulomb and exchange terms from the BSE Hamiltonian,their respective contributions are disentangled—exchange interaction is found to increase the number of accessible recombination pathways,while binding reduces the excitation energy and enhances nonradiative decay.A reduction in recombination lifetime by over an order of magnitude is observed due to the excitonic many-body effects.These findings provide microscopic insights for understanding and tuning exciton lifetimes in 2D transition-metal dichalcogenides.
基金supported by the Yanzhao Gold Talent Project of Hebei Province(NO.HJZD202506)。
文摘Objective Previous studies link lower body mass index(BMI)with increased obsessive-compulsive disorder(OCD)risk,yet other body mass indicators may be more etioloically relevant.We dissected the causal association between body fat mass(FM)and OCD.Methods Summary statistics from genome-wide association studies of European ancestry were utilized to conduct two-sample Mendelian randomization analysis.Heterogeneity,horizontal pleiotropy,and sensitivity analyses were performed to assess the robustness.Results The inverse variance weighting method demonstrated that a genetically predicted decrease in FM was causally associated with an increased OCD risk[odds ratio(OR)=0.680,95%confidence interval(CI):0.528–0.875,P=0.003].Similar estimates were obtained using the weighted median approach(OR=0.633,95%CI:0.438–0.915,P=0.015).Each standard deviation increases in genetically predicted body fat percentage corresponded to a reduced OCD risk(OR=0.638,95%CI:0.455–0.896,P=0.009).The sensitivity analysis confirmed the robustness of these findings with no outlier instrument variables identified.Conclusion The negative causal association between FM and the risk of OCD suggests that the prevention or treatment of mental disorders should include not only the control of BMI but also fat distribution and body composition.
基金supported by the Special Project of National Science and Technology Basic Resources Survey(Grant No.2017FY101100)。
文摘Objective The rising prevalence of childhood obesity is closely associated with suboptimal dietary patterns.To address this public health concern,we conducted a comprehensive study to examine the association between coarse cereals consumption and body fat percentage(BFP)in Chinese children and adolescents.Methods The study included 48,305 children aged 6–17 years from 28 districts/counties in 14 provinces across seven regions of China(24,152 girls and 24,153 boys).BFP was examined using bioelectrical impedance analysis in the early morning.Coarse cereals consumption was assessed using a Food Frequency Questionnaire and categorized into three groups:0 g/1,000 kcal per day,0–10 g/1,000kcal per day,and>10 g/1,000 kcal per day(daily consumption of coarse cereals×1,000/total energy consumption).Quantile regression model was used to analyze the association between coarse cereals and BFP,adjusting for potential confounders such as age,pubertal development stage,urban/rural and regional factors,total daily dietary energy consumption,sedentary time,moderate-to-high physical activity,household income,parental education,and consumption of other foods.Results Boys aged 6–10,11–14,and 15–17 years had median daily coarse cereals consumptions of6.6 g,7.1 g,and 5.7 g,with BFP of 19.6%,19.5%,and 17.5%(all P<0.05).Girls in the same age groups showed consumption of 7.1 g,8.4 g,and 6.7 g,with BFP of 20.3%,26.4%,and 31.0%(all P<0.05).The quantile regression results for boys showed that daily consumption of coarse cereals was significantly correlated with their BFP in the 0.15,0.25,and 0.50 quartiles,with regression coefficients of-0.257,-0.221,and-0.330,respectively,after adjusting for potential confounders(P<0.05).For girls,there was a significant correlation with PBF at the 0.05,0.15,0.25,0.50,0.75,and 0.85 quartiles,with regression coefficients of-0.258,-0.366,-0.372,-0.431,-0.472,and-0.503(P<0.05 for all).Conclusions Coarse cereals consumption among Chinese children and adolescents remains relatively low.Higher consumption was inversely associated with BFP in children aged 6–17 years.Future interventional studies should assess how increased coarse cereals consumption prevents childhood obesity.
基金supported by the National Natural Science Foundation of China(No.71974162 and No.7231101009).
文摘Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development process of the MBC App involved:1)establishing a research group;2)determining of the content of the MBC App based on Mindfulness-Based Cognitive Therapy and 3)technical exploitation and maintenance.A mixed-methods study was conducted.We selected ten BCSs by a convenience sampling method.After using the APP for three months,five assessed the quality using the Mobile App Rating Scale:User Version(uMARS)and another five were interviewed for process evaluation.Results The MBC App was developed with three modules:1)Library to provide health education information on body image,stigma,mindfulness,recovery and etc;2)Mindfulness Yoga to offer 12 Hatha yoga videos for daily practice;and 3)Mindfulness Practices to have 12 sessions of mindfulness videoconferences.Based on the uMARS data,the MBC App received high ratings for functionality(4.10±0.34),aesthetics(3.93±0.55),information quality(4.10±0.72),and perceived impact(4.03±0.96),as well as moderate ratings for engagement(3.72±0.94)and subjective quality(3.87±0.77).Participants indicated that the MBC App provided reliable knowledge,information,and emotional support.Recommendations from participants included categorizing knowledge in the Library Module,recording videoconferences of mindfulness practice,and adding discussion sessions in the videoconference.Afterward,we optimized the MBC App to enhance the user experience accordingly.Conclusions The MBC App offers online mindfulness interventions specifically for BCSs in China.The preliminary quality assessment indicates that the MBC App may be a promising tool for delivering mindfulness interventions to BCSs.
文摘BACKGROUND Acute liver failure(ALF)is a life-threatening multisystemic condition with high short-term mortality.With the growing prevalence of obesity and metabolic syndrome,it is important to investigate the clinical implications of high body mass index(BMI)on survival outcomes in ALF.AIM To explore the impact of overweight and obesity on the clinical outcomes of patients with ALF.METHODS A retrospective observational cohort study was conducted involving patients with ALF admitted to the Johns Hopkins Health System between January 1,2000 and May 1,2020.We performed Cox proportional hazards regression to identify outcomes,including the need for liver transplantation(LT)or all-cause mortality.RESULTS A total of 196 patients were included,the median age was 43.5 years,63.3%were female,and 59.7%were of Caucasian ethnicity.Acetaminophen-induced ALF was the most common etiology(45%).The mean BMI was significantly greater among patients who underwent LT or died(29.64 kg/m^(2)vs 26.59 kg/m^(2),P=0.008)than among survivors.Patients with overweight and obesity had a higher risk of all-cause mortality or need for LT by 2.22-fold(95%CI:1.30-3.78)and 2.04-fold(95%CI:1.29-3.39),respectively.Elevated BMI was associated with renal failure and higher grades of hepatic encephalopathy.Derangements in serologic markers,including alanine transaminase,lactate,and ammonia,were associated with a mortality risk or need for LT.CONCLUSION In this large,retrospective study,with a diverse cohort of United States patients,Overweight and obese were independently associated with an increased risk of all-cause mortality or need for LT.This work highlights the importance of closely monitoring ALF patients who are overweight or obese for adverse complications and measures to improve outcomes in this vulnerable patient population.
基金Supported by The University of Kelaniya,Sri Lanka,Research Council Grant No.G23.
文摘BACKGROUND Overweight children exhibit a higher prevalence of functional gastrointestinal disorders compared with their normal-weight peers,yet the underlying reasons remain unclear.Gastrointestinal motility,a key pathophysiological factor in functional gastrointestinal disorders,may be influenced by body mass index(BMI).AIM To evaluate the impact of BMI on gastric motility parameters in children with functional abdominal pain disorders(FAPDs).METHODS We assessed gastric motility in 176 children with FAPDs(61.4%females,mean age 7.94 years,SD 1.96 years)and 63 healthy controls(57.1%females,mean age 9.17 years,SD 1.90 years)at the Gastroenterology Research Laboratory,University of Kelaniya,Sri Lanka.FAPDs were diagnosed and subtyped using the Rome IV criteria:Functional abdominal pain 97 patients;irritable bowel syndrome 39 patients,functional dyspepsia(FD)25 patients;and abdominal migraine 15 patients.Gastric motility was measured using a validated ultrasound method.Weight and height were measured using sensitive standard scales.RESULTS The BMIs of children with FAPDs and controls were 15.04 and 15.46 kg/m^(2),respectively(P=0.33).Fasting antral area(FAA)and antral area at 1 min(AA1)and 15 min(AA15)were significantly greater in patients with FAPD with a higher BMI(2.71 cm^(2),12.57 cm^(2),and 7.19 cm^(2),respectively)compared with those with a lower BMI(2.12 cm^(2),10.68 cm^(2),and 6.13 cm^(2),respectively)(P<0.01).BMI positively correlated with FAA and AA15(r=0.18 and r=0.19,respectively)(P<0.01)in those with FAPDs.In controls,only AA1 was greater in the higher BMI group(12.51 cm^(2)vs 9.93 cm^(2))and had a positive correlation(r=0.33)(P≤0.01).Subgroup analysis revealed that in patients with FD,BMI negatively correlated with gastric emptying rate(GER)(r=-0.59)and antral motility index(MI)(r=-0.49),while in functional abdominal pain,MI positively correlated(r=0.25)with BMI(P≤0.01).CONCLUSION In children with FAPDs,higher BMI was associated with increased gastric antral distention during fasting and postprandial periods(as indicated by FAA,AA1,and AA15)but not with contractility and transit(MI,GER).However,in the FD subgroup,high BMI correlated with reduced GER and MI.This indicates the possible role of BMI in gastric hypomotility and the pathophysiology of FD.These findings underscore the importance of lifestyle and dietary interventions aimed at optimizing BMI in the management of FAPDs,particularly FD.
文摘The concept of emissivity has been with the scientific and engineering world since Planck formulated his blackbody radiation law more than a century ago.Nevertheless,emissivity is an elusive concept even for ex⁃perts.It is a vague and fuzzy concept for the wider community of engineers.The importance of remote sensing of temperature by measuring IR radiation has been recognized in a wide range of industrial,medical,and environ⁃mental uses.One of the major sources of errors in IR radiometry is the emissivity of the surface being measured.In real experiments,emissivity may be influenced by many factors:surface texture,spectral properties,oxida⁃tion,and aging of surfaces.While commercial blackbodies are prevalent,the much-needed grey bodies with a known emissivity,are unavailable.This study describes how to achieve a calibrated and stable emissivity with a blackbody,a perforated screen,and a reliable and linear novel IR thermal sensor,18 dubbed TMOS.The Digital TMOS is now a low-cost commercial product,it requires low power,and it has a small form factor.The method⁃ology is based on two-color measurements,with two different optical filters,with selected wavelengths conform⁃ing to the grey body definition of the use case under study.With a photochemically etched perforated screen,the effective emissivity of the screen is simply the hole density area of the surface area that emits according to the blackbody temperature radiation.The concept is illustrated with ray tracing simulations,which demonstrate the approach.Measured results are reported.
文摘The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore how young people respond to the increasing focus on body weight management.As obesity rates climb,body weight management has become a growing concern in China.The government is introducing targeted policies,hospitals are setting up dedicated clinics,and health experts are speaking out.But weight is no longer just a medical issue-it’s increas-ingly tied to identity,confidence,and social image.We examine the cultural forces shaping how young people in China and Africa approach weight-what drives their choices,how ideals are formed,and where health meets appearance in today’s shifting societies.
基金financially supported by the Vice-Rector’s Office for Research and Transfer at the University of Granada(Grant Ref.PPJIB2023-084)Spanish Ministry of Universities(Grants Ref.FPU20/02739 and FPU20/01987)+1 种基金Maria de Maeztu Excellence Unit Program funded by the Ministry of Science,Innovation and Ministry of Universities attached to the State Research Agency(Grant Ref.CEX2023-001312-M/AEI/10.13039/501100011033)the Excellence Unit funded by the University of Granada(Grant Ref.UCE-PP2023-11/UGR.).
文摘Background:University students face significant challenges inmaintaining healthy physical activity(PA)and dietary habits,and they often fall short of global health recommendations.Psychological factors such as social physique anxiety,body image concerns,and self-objectification may act as barriers to PA engagement,influencing both mental and physical health.The present study constructed a structural equation model(SEM)to examine the relationship between body image-related psychological factors and resistance to PA in university students from southern Spain.Methods:A cross-sectional and correlational study was conducted with 519 university students(74%females,26%males;Mean age=21.14±3.26 years)from universities in Granada and Malaga(Spain).Data were collected between May and October 2024 via online questionnaires that assessed PA engagement,Mediterranean diet adherence,eating disorder symptoms,body image-related psychological factors(social physique anxiety,appearance control beliefs,body surveillance,body shame,and self-esteem),and sociodemographic characteristics.SEM was performed to analyze relationships and sex-based differences.Results:Social physique anxietywas positively associated with body shame,body surveillance,and eating disorders,and negatively associated with self-esteem,PA engagement,and appearance control beliefs(all p<0.001).Appearance control beliefs were positively related to self-esteem,body surveillance,and PA(all p<0.05).Body surveillance was negatively linked to PA and positively linked to body shame.Mediterranean diet adherence and eating disorders were positively associated with PA(all p<0.001).Sex-based differences were observed in the model.Conclusion:Body image-related psychological factors may act as barriers to PA among university students.Interventions should integrate mental health promotion and consider sex differences.
文摘Body mass index(BMI),with its simple formula of weight divided by height squared,has become a cornerstone tool in global public health for assessing obesity and health risks.However,as populations aging and the demand for precise health evaluation grows,the limitations of this single metric have become increasingly apparent—it fails to distinguish between muscle and adipose tissue and cannot capture the complex relationship between inflammatory status and body composition.A recent study published in Biomedical and Environmental Sciences(BES)by Zhang et al.[1],which explores the association of white blood cell(WBC)count,platelet(PLT)count,and platelet-to-white blood cell ratio(PWR)with muscle mass among Chinese communitydwelling older adults,provides critical evidence for rethinking the role of BMI.Additionally,several studies published in BES,spanning from childhood nutrition to adult metabolism,further illuminate the complexity of health assessment[2−5].Building on these findings and integrating evidence from multiple Chinese population studies,this commentary revisits the historical context,utility,inherent limitations,and future directions of this classic indicator.
基金This study is supported by the National Natural Science Foundation of China (No. 82072127)。
文摘BACKGROUND:This study aims to explore the causal relationship of body weight,body mass index(BMI),and waist circumference (WC) with the risk of cardiac arrest (CA) using two-sample Mendelian randomization (MR).METHODS:Data were summarized using genome-wide association studies (GWAS).Twosample MR analyses were performed using the inverse variance weighting (IVW) method,the weighted median method,and the MR-Egger analysis.Heterogeneity test and sensitivity analysis were performed using Cochran’s Q test and the leave-one-out method,respectively.The Steiger test was used to detect reverse causality.Bayesian model-averaged MR was used to identify the most influential risk factors.RESULTS:A total of 13 GWAS data were collected for BMI,body weight and WC.IVW analyses showed a positive correlation of body weight,BMI,and WC with CA (all OR>1 and P<0.05),with MR-Egger and weighted median methods confirming the IVW findings.No horizontal pleiotropy or heterogeneity was observed.Sensitivity analysis indicated that no single nucleotide polymorphism(SNP) caused significant changes in overall causality.Bayesian model-averaged MR was also used to rank causality based on marginal inclusion probability (MIP),and the corresponding modelaveraged causal estimate (MACE) were confirmed,which indicated that WC (GWAS ID:ukb-b-9405)was the highest-ranked risk factor (MIP=0.119,MACE=0.011);its posterior probability was 0.057.A total of 14 sex-specific GWAS data on weight,BMI,and WC were analyzed in relationship with CA,and the MR results showed no significant effects of sex-specific factors.CONCLUSION:Body weight,BMI,and WC are causally associated with an increased risk of CA,with WC identified as the most important risk factor.
基金funded by the National Natural Science Foundation of China(52474131)the National Natural Science Foundation of China(42467022)+1 种基金the Yunnan Major Scientific and Technological Projects(Grant No.202202AG050014)the Yunnan Fundamental Research Projects(NO.202101BE070001-038,202201AT070146).
文摘The strength of backfill body is a crucial parameter in backfilling mining,and the failure process of cemented backfill body is essentially an energy dissipation process.To investigate the effects of curing age and cement-sand ratio on the strength and energy consumption of backfill,whole tailings were used as aggregate to prepare slurry with mass concentration of 74%,and the slurry with cement-sand ratio of 1:4,1:6,1:8 and 1:12 was poured into backfill.Uniaxial compression tests were conducted on backfill body specimens that had been cured for 7 days,14 days,28 days,and 45 days.It aims at studying the compressive strength,damage,energy storage limit,energy dissipation,and crack propagation of the fill.The results show that when the cement-sand ratio is held constant,the strength of the backfill increases with curing age.Simultaneously,when the curing age is fixed,the strength is positively correlated with the cement-sand ratio.During uniaxial compression tests,it is observed that the pre-peak energy consumption,post-peak energy consumption,total energy consumption,and unit volume strain energy of the cemented backfill body exhibit exponential relationships with both curing age and cement-sand ratio.The energy storage limit of the backfill reflects its capacity to absorb energy prior to failure,while the relationship between damage and energy consumption provides an accurate depiction of its internal failure mechanisms at different stages.In the failure process of the cemented backfill body,primary cracks accompany secondary cracks,many microcracks initiate and propagate from the stress direction,and crack propagation consumes a significant amount of energy.This study on the strength,energy storage limit,and failure of the cemented backfill body can provide valuable insights for mine safety production.
文摘Have you ever imagined that home robots can not only help you clean,but also read you,chat and play chess with you and even take good care of you when you are sick?These are no longer scenes in science fiction movies,but reality that is happening.With the rapid development of Embodied Intelligence technology,robots are evolving from“tools”to“partners”.As cold machines are given“body temperature”,an intelligent revolution has begun quietly.
基金Supported by Ministry of Science,Technological Development and Innovations,Republic of Serbia,No.451-03-66/2024-03/200110.
文摘The minireview titled“Modern endoscopist’s toolbox:Innovations in foreign body removal”by Shahid and published in the World Journal of Gastrointestinal Endoscopy provided a clear and comprehensive overview of endoscopic management of gastrointestinal foreign bodies.It will serve as a valuable resource for endoscopists involved in the diagnosis and treatment of such cases.Several key and controversial aspects of patient management were highlighted in a meaningful way,including the importance of thorough medical history-taking,appropriate use of radiological imaging,and the selection of suitable endoscopic extraction techniques.An individualized,multidisciplinary approach is essential for diagnosis and treatment.While current guidelines offer significant support,they cannot replace the judgment of an experienced endoscopist working with a well-trained team.
文摘Foreign body ingestion is a common gastrointestinal emergency,particularly in children,who account for 80%of cases.While most ingested objects pass spontan-eously,around 20%require medical intervention.In adults,incidents often occur accidentally during meals,leading to impactions,especially in individuals with underlying esophageal conditions.Endoscopy remains the gold standard for foreign body retrieval,with a success rate exceeding 95%.The type,shape,and location of the foreign body determine the clinical presentation and management approach.Sharp objects,batteries,and large items pose the highest risk of complications,including perforation,obstruction,and chemical injury.Prompt endoscopic removal is guided by established protocols,with emergent inter-vention required for complete esophageal obstruction and high-risk objects.Various retrieval devices,including forceps,snares,baskets,and overtubes,are used based on the nature of the foreign body.Technological advancements,such as artificial intelligence-assisted imaging and endoscopic ultrasound,are impro-ving diagnostic precision and procedural outcomes.Despite these advances,foreign body ingestion can still lead to severe complications if not managed in a timely manner.Public awareness,preventive measures,and rapid medical res-ponse are essential in reducing morbidity and mortality associated with foreign body ingestion.
