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GaN-based blue laser diodes with output power of 5 W and lifetime over 20000 h aged at 60℃
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作者 Lei Hu Siyi Huang +6 位作者 Zhi Liu Tengfeng Duan Si Wu Dan Wang Hui Yang Jun Wang Jianping Liu 《Journal of Semiconductors》 2025年第4期9-11,共3页
Stimulated emission and lasing of GaN-based laser diodes(LDs)were reported at 1995[1]and 1996[2],right after the breakthrough of p-type doping[3−5],material quality[6]and the invention of high-brightness GaN-based LED... Stimulated emission and lasing of GaN-based laser diodes(LDs)were reported at 1995[1]and 1996[2],right after the breakthrough of p-type doping[3−5],material quality[6]and the invention of high-brightness GaN-based LEDs[7,8].However,it took much longer time for GaN-based LDs to achieve high power,high wall plug efficiency,and long lifetime.Until 2019,Nichia reported blue LDs with these performances[9],which open wide applications with GaN-based blue LDs. 展开更多
关键词 blue laser diodes P type doping LIFETIME Output power Stimulated emission GAN based laser diodes stimulated emission lasing laser diodes lds
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GaN-based blue laser diode with 6.0 W of output power under continuous-wave operation at room temperature 被引量:8
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作者 Feng Liang Degang Zhao +5 位作者 Zongshun Liu Ping Chen Jing Yang Lihong Duan Yongsheng Shi Hai Wang 《Journal of Semiconductors》 EI CAS CSCD 2021年第11期70-72,共3页
In this work,we reported the room-temperature continuous-wave operation of 6.0 W GaN-based blue laser diode(LD),and its stimulated emission wavelength is around 442 nm.The GaN-based high power blue LD is grown on a c-... In this work,we reported the room-temperature continuous-wave operation of 6.0 W GaN-based blue laser diode(LD),and its stimulated emission wavelength is around 442 nm.The GaN-based high power blue LD is grown on a c-plane GaN substrate by metal organic chemical vapor deposition(MOCVD),and the width and length of the ridge waveguide structure are 30 and 1200μm,respectively.The threshold current is about 400 mA,and corresponding threshold current density is 1.1 kA/cm2. 展开更多
关键词 GAN blue laser diode high power
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Effect of Droop Phenomenon in InGaN/GaN Blue Laser Diodes on Threshold Current
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作者 Xiao-Wang Fan Jian-Ping Liu +8 位作者 Feng Zhang Masao Ikeda De-Yao Li Shu-Ming Zhang Li-Qun Zhang Ai-Qin Tian Peng-Yan Wen Guo-Hong Ma Hui Yang 《Chinese Physics Letters》 SCIE CAS CSCD 2017年第9期109-111,共3页
Electroluminescence (EL) and temperature-dependent photolumineseenee measurements are performed to study the internal quantum efficiency droop phenomenon of blue laser diodes (LDs) before lasing. Based on the ABC ... Electroluminescence (EL) and temperature-dependent photolumineseenee measurements are performed to study the internal quantum efficiency droop phenomenon of blue laser diodes (LDs) before lasing. Based on the ABC mode, the EL result demonstrates that non-radiative recombination rates of LDs with threshold current densities of 4 and 6kA/cm2 are similar, while LD with threshold current density of 4kA/cm2 exhibits a smaller auger- like recombination rate compared with the one of 6kA/cm2. The internal quantum efficiency droop is more serious for LD with higher threshold current density. temperature-dependent photoluminescence is consistent The internal quantum efficiency value estimated from with EL measurements. 展开更多
关键词 INGAN LD Effect of Droop Phenomenon in InGaN/GaN blue laser Diodes on Threshold Current
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In vivo pilot study into superficial microcirculatory characteristics of colorectal adenomas using novel high-resolution magnifying endoscopy with blue laser imaging
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作者 Hai-Bin Dong Tao Chen +2 位作者 Xiao-Fei Zhang Yu-Tang Ren Bo Jiang 《World Journal of Gastrointestinal Endoscopy》 2024年第4期206-213,共8页
BACKGROUND No studies have yet been conducted on changes in microcirculatory hemody-namics of colorectal adenomas in vivo under endoscopy.The microcirculation of the colorectal adenoma could be observed in vivo by a n... BACKGROUND No studies have yet been conducted on changes in microcirculatory hemody-namics of colorectal adenomas in vivo under endoscopy.The microcirculation of the colorectal adenoma could be observed in vivo by a novel high-resolution magnification endoscopy with blue laser imaging(BLI),thus providing a new insight into the microcirculation of early colon tumors.AIM To observe the superficial microcirculation of colorectal adenomas using the novel magnifying colonoscope with BLI and quantitatively analyzed the changes in hemodynamic parameters.METHODS From October 2019 to January 2020,11 patients were screened for colon adenomas with the novel high-resolution magnification endoscope with BLI.Video images were recorded and processed with Adobe Premiere,Adobe Photoshop and Image-pro Plus software.Four microcirculation parameters:Microcirculation vessel density(MVD),mean vessel width(MVW)with width standard deviation(WSD),and blood flow velocity(BFV),were calculated for adenomas and the surrounding normal mucosa.RESULTS A total of 16 adenomas were identified.Compared with the normal surrounding mucosa,the superficial vessel density in the adenomas was decreased(MVD:0.95±0.18 vs 1.17±0.28μm/μm2,P<0.05).MVW(5.11±1.19 vs 4.16±0.76μm,P<0.05)and WSD(11.94±3.44 vs 9.04±3.74,P<0.05)were both increased.BFV slowed in the adenomas(709.74±213.28 vs 1256.51±383.31μm/s,P<0.05).CONCLUSION The novel high-resolution magnification endoscope with BLI can be used for in vivo study of adenoma superficial microcirculation.Superficial vessel density was decreased,more irregular,with slower blood flow. 展开更多
关键词 ADENOMA MICROCIRCULATION High-resolution magnification endoscopy blue laser imaging
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Short Pulse Width and High Peak Power 457 nm Deep Blue Laser with V-Type Cavity
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作者 Zhibin Zhao Cheng Cheng +5 位作者 Hao Chen Quan Li Yi Qu Guojun Liu Zhongliang Qiao Baoxue Bo 《Journal of Applied Mathematics and Physics》 2021年第11期2987-2994,共8页
<div style="text-align:justify;"> An intracavity frequency doubling acousto-optically Q-switched Neodymium-doped Yttrium Orthvanadate (Nd:YVO<sub>4</sub>) 457 nm blue laser by employing a t... <div style="text-align:justify;"> An intracavity frequency doubling acousto-optically Q-switched Neodymium-doped Yttrium Orthvanadate (Nd:YVO<sub>4</sub>) 457 nm blue laser by employing a three-mirror folded cavity was demonstrated. With the incident pump power of 40.4 W, the maximum average output power of 439 mW 457 nm laser, and the minimum pulse duration of 86.14 ns and the maximum peak power of 510 W were achieved at 10 kHz. The M<sup>2</sup> factors are 1.23 and 1.61 in X and Y directions, respectively. The power stability in two hours is better than 2%. </div> 展开更多
关键词 laser All-Solid-State laser Pulse Wave Deep blue laser 457 nm laser
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Infrared Laser Pumped Green and Blue Laser Emissions from a Single Solid State Material Doped by Rare Earth Ions
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作者 黄艺东 黄妙良 +1 位作者 陈雨金 罗遵度 《Journal of Rare Earths》 SCIE EI CAS CSCD 2003年第3期307-314,共8页
The possible ways and progress of infrared or red laser pumped green and blue laser emissions from a single solid state material doped by rare earth ions are outlined. The green and blue lasers realized from infrared ... The possible ways and progress of infrared or red laser pumped green and blue laser emissions from a single solid state material doped by rare earth ions are outlined. The green and blue lasers realized from infrared laser pumped rare earth doped nonlinear laser crystals by means of self frequency conversion and from infrared laser pumped rare earth doped bulk, fiber and microsphere materials by means of frequency upconversion are introduced in detail. Other kinds of devices and methods are also compared. The typical nonlinear laser crystals such as YAl 3(BO 3) 4, GdAl 3(BO 3) 4, YCa 4O(BO 3) 3 , GdCa 4O(BO 3) 3, and the typical upconversion fluoride fibers are compared and analyzed. The major problems remaining to be solved and the developing trends in the area are also discussed. 展开更多
关键词 OPTICS solid state laser material blue and green lasers rare earth
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20.231 Gbit/s tricolor red/green/blue laser diode based bidirectional signal remodulation visible-light communication system 被引量:8
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作者 LIANG-YU WEI CHIN-WEI HSU +1 位作者 CHI-WAI CHOW CHIEN-HUNG YEH 《Photonics Research》 SCIE EI 2018年第5期422-426,共5页
We propose and experimentally demonstrate a recorded 1-m bidirectional 20.231-Gbit/s tricolor R/G/B laser diode(LD) based visible-light communication(VLC) system supporting signal remodulation. In the signal remodulat... We propose and experimentally demonstrate a recorded 1-m bidirectional 20.231-Gbit/s tricolor R/G/B laser diode(LD) based visible-light communication(VLC) system supporting signal remodulation. In the signal remodulation system, an LD source is not needed at the client side. The client reuses the downstream signal sent from the central office(CO) and remodulates it to produce the upstream signal. As the LD sources are located at the CO, the laser wavelength and temperature managements at the cost-sensitive client side are not needed.This is the first demonstration, to our knowledge, of a >20 Gbit∕s data rate tricolor R/G/B VLC signal transmission supporting upstream remodulation. 展开更多
关键词 bidirectional signal remodulation visible-light communication system blue laser
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Low-pump sum frequency generation of frequency- stabilized 453 nm blue laser for photonic quantum interface
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作者 王健 潘宇豪 +2 位作者 黄运锋 李传锋 郭光灿 《Chinese Optics Letters》 SCIE EI CAS CSCD 2017年第12期82-85,共4页
Generation of a cavity-enhanced nondegenerate narrow-band photon pair source is a potential way to realize a perfect photonic quantum interface for a hybrid quantum network. However, to ensure the high quality of the ... Generation of a cavity-enhanced nondegenerate narrow-band photon pair source is a potential way to realize a perfect photonic quantum interface for a hybrid quantum network. However, to ensure the high quality of the photon source, the pump laser for the narrow-band photon source should be generated in a special way. Here, we experimentally generate the blue 453 nm laser with a sum frequency generation process in a periodically poled lithium niobate waveguide. A 13 mW laser at 453 nm can be achieved with a low-power 880 nm laser and 935 nm laser input, and the internal conversion efficiency is 21.6% after calculation. The frequency of a 453 nm laser is stabilized by locking two pump lasers on one ultrastable optical cavity. The single pass process without employ- ing cavity enhancement can ensure a good robustness of the whole system. 展开更多
关键词 Low-pump sum frequency generation of frequency-stabilized 453 nm blue laser for photonic quantum interface
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Room-temperature continuous-wave operation of GaN-based blue-violet laser diodes with a lifetime longer than 1000h 被引量:5
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作者 Feng Liang Jing Yang +9 位作者 Degang Zhao Zongshun Liu Jianjun Zhu Ping Chen Desheng Jiang Yongsheng Shi Hai Wang Lihong Duan Liqun Zhang Hui Yang 《Journal of Semiconductors》 EI CAS CSCD 2019年第2期39-42,共4页
GaN-based continuous-wave operated blue-violet laser diodes(LDs) with long lifetime are demonstrated, which are grown on a c-plane GaN substrate by metal organic chemical vapor deposition with a 10 × 600 μm^2 ri... GaN-based continuous-wave operated blue-violet laser diodes(LDs) with long lifetime are demonstrated, which are grown on a c-plane GaN substrate by metal organic chemical vapor deposition with a 10 × 600 μm^2 ridge waveguide structure.The electrical and optical characteristics of a blue-violet LD are investigated under direct-current injection at room temperature(25 °C). The stimulated emission wavelength and peak optical power of the LD are around 413 nm and over 600 mW, respectively.In addition, the threshold current density and voltage are as small as 1.46 kA/cm^2 and 4.1 V, respectively. Moreover, the lifetime is longer than 1000 hours under room-temperature continuous-wave operation. 展开更多
关键词 GAN-BASED blue-violet laser DIODES long LIFETIME threshold voltage
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Design of NO2 photoacoustic sensor with high reflective mirror based on low power blue diode laser 被引量:2
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作者 Hua-Wei Jin Pin-Hua Xie +3 位作者 Ren-Zhi Hu Chong-Chong Huang Chuan Lin Feng-Yang Wang 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第6期139-145,共7页
An NO2 photoacoustic sensor system with a high reflective mirror based on a low power blue diode laser is developed in this work. The excitation power is enhanced by increasing the number of reflections. Comparing wit... An NO2 photoacoustic sensor system with a high reflective mirror based on a low power blue diode laser is developed in this work. The excitation power is enhanced by increasing the number of reflections. Comparing with a traditional photoacoustic system, the pool constant is improved from 300.24(Pa·cm)/W to 1450.64(Pa·cm)/W, and the signal sensitivity of the photoacoustic sensor is increased from 0.016 μV/ppb to 0.2562 μV/ppb. The characteristics of temperature and humidity of the new photoacoustic sensor are also obtained, and the algorithm is adjusted to provide a quantitative response and drift of the resonance frequency. The results of this research provide a new method and concept for further developing the NO2 photoacoustic sensors. 展开更多
关键词 NO2 photoacoustic sensor high reflective mirror blue diode laser
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A 420nm Blue Diode Laser for the Potential Rubidium Optical Frequency Standard 被引量:1
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作者 张盛楠 张晓刚 +6 位作者 涂建辉 蒋招杰 商浩森 祝传文 杨炜 崔敬忠 陈景标 《Chinese Physics Letters》 SCIE CAS CSCD 2017年第7期118-121,共4页
We report a 42Ohm external cavity diode laser with an interference filter (IF) of 0.5am narrow-bandwidth and 79% high transmission, which is first used for Rb optical frequency standard. The IF and the cat-eye refle... We report a 42Ohm external cavity diode laser with an interference filter (IF) of 0.5am narrow-bandwidth and 79% high transmission, which is first used for Rb optical frequency standard. The IF and the cat-eye reflector are used for selecting wavelength and light feedback, respectively. The measured laser linewidth is 24 kHz when the diode laser is free running. Using this narrow-linewidth IF blue diode laser, we realize a compact Rb optical frequency standard without a complicated PDH system. The preliminary stability of the Rb optical frequency standard is 2 × 10^-13 at I s and decreases to 1.9 ×10^-14 at 1000s. The narrow-linewidth characteristic makes the IF blue diode laser a well suited candidate for the compact Rb optical frequency standard. 展开更多
关键词 A 420nm blue Diode laser for the Potential Rubidium Optical Frequency Standard RB KHZ
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The Photopolymerization Kinetics of Acryl amide Sensitized with Toluidine Blue-Alcoholamine Induced by He-Ne Laser
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作者 FENG Min-hui, HE Wei-qiang, HE Yi and LIANG Zhao-xi (Institute of Polymer Science, Zhongshan University, Guangzhou, 510275) 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1993年第4期329-334,共6页
Toluidine blue(TB) is a good sensitizer for the polymerization of acrylnmide(AM) induced by He-Ne laser. With TB as a sensitizer and various alcoholamine as donors, the photoredox of TB and the polymerization kinetics... Toluidine blue(TB) is a good sensitizer for the polymerization of acrylnmide(AM) induced by He-Ne laser. With TB as a sensitizer and various alcoholamine as donors, the photoredox of TB and the polymerization kinetics of AM induced by He-Ne laser were investigated. It was found that either for the photoredox of TB or for the polymerization of AM, the activity of alcoholamine increases in the order of EOA<DEOA <TEOA in TB-alcoholamine sensitized system. The overall apparent kinetic equations of AM polymerization at 30℃ have been determined. In addition, the molecular weights under various conditions was measured. 展开更多
关键词 He-Ne laser PHOTOPOLYMERIZATION Acryiamide Toluidine blue Alcoho-lamine
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高功率GaN基蓝光二极管激光器性能退化实验研究
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作者 谢鹏飞 张永刚 +6 位作者 王丞乾 吕文强 武德勇 郭林辉 雷军 王昭 高松信 《强激光与粒子束》 北大核心 2026年第1期1-7,共7页
高功率GaN基蓝光二极管激光器在工业加工、铜材料焊接、3D打印和水下激光通信等技术领域有着广泛的应用前景。蓝光二极管激光芯片COS单元器件具有热阻低和尺寸小的优点,但是该器件存在可靠性较低的问题,导致其在工业化应用中受到一定限... 高功率GaN基蓝光二极管激光器在工业加工、铜材料焊接、3D打印和水下激光通信等技术领域有着广泛的应用前景。蓝光二极管激光芯片COS单元器件具有热阻低和尺寸小的优点,但是该器件存在可靠性较低的问题,导致其在工业化应用中受到一定限制,因此对其性能退化因素进行深入研究。基于光学显微技术、扫描电子显微表征和能谱分析手段对经过长时老化考核后器件的性能退化因素进行分析研究。实验研究和分析表明,GaN基体材料缺陷、腔面多余物沉积和光化学腐蚀是导致蓝光二极管激光芯片性能退化的主因,同时良好的气密性封装可提高二极管激光芯片的可靠性。 展开更多
关键词 高功率GaN蓝光二极管激光器 性能退化 二极管激光器封装 气密封
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经尿道前列腺蓝激光汽化术与经尿道前列腺电切术或等离子切除术治疗良性前列腺增生安全性与疗效荟萃分析
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作者 霍仲超 程海峰 +7 位作者 何泳志 王磊 丁瑞 杨建琪 赵雯婷 才子 孔彩英 高一萍 《现代泌尿外科杂志》 2026年第2期140-146,共7页
目的比较经尿道前列腺蓝激光汽化术与经尿道前列腺电切术(TURP)或等离子切除术治疗良性前列腺增生(BPH)的疗效与安全性。方法计算机检索(2015年1月—2025年3月)国内外有关经尿道前列腺蓝激光汽化术(观察组)与TURP或等离子切除术(对照组... 目的比较经尿道前列腺蓝激光汽化术与经尿道前列腺电切术(TURP)或等离子切除术治疗良性前列腺增生(BPH)的疗效与安全性。方法计算机检索(2015年1月—2025年3月)国内外有关经尿道前列腺蓝激光汽化术(观察组)与TURP或等离子切除术(对照组)治疗BPH的临床研究,按Cochrane系统评价方法提取资料,采用RevMan5.3.0统计软件对两组手术时间、血红蛋白下降程度、膀胱冲洗时间、留置尿管时间、总并发症、逆行射精及尿失禁发生率等指标进行荟萃分析。结果最终纳入5篇中文文献进行荟萃分析,共491例患者(观察组248例、对照组243例)。与对照组相比,观察组手术时间更短[MD=-20.80,95%CI:-26.88~-14.72,P<0.00001]、血红蛋白下降程度更小[MD=-10.61,95%CI:-20.21~-1.01,P=0.03]、膀胱冲洗时间[MD=-17.85,95%CI:-32.62~-3.09,P=0.002]及留置尿管时间均更短[MD=-1.71,95%CI:-2.81~-0.62,P=0.002]、总并发症发生率[OR=0.11,95%CI:0.06~0.21,P<0.00001]、逆行射精发生率[OR=0.05,95%CI:0.02~0.16,P<0.00001]及尿失禁发生率均更低[OR=0.24,95%CI:0.07~0.79,P=0.02]。两组间其他并发症比较,差异均无统计学意义(P>0.05)。观察组术后国际勃起功能专项评分(IIEF-5)高于对照组[MD=1.87,95%CI:1.16~2.57,P<0.00001];两组的国际前列腺症状评分(IPSS)、最大尿流率(Qmax)及残余尿量(PVR)比较,差异均无统计学意义(P>0.05)。结论三种术式均能有效改善BPH患者的下尿路症状;与TURP或等离子切除术比,经尿道前列腺蓝激光汽化术在围手术期恢复,降低总并发症、尿失禁及逆行射精发生率,保留性功能等方面具有明显优势。 展开更多
关键词 450 nm半导体蓝激光 前列腺汽化切除术 经尿道前列腺等离子切除术 经尿道前列腺电切术 良性前列腺增生 下尿路症状 荟萃分析
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450nm蓝激光前列腺汽化剜除术治疗前列腺增生疗效及安全性的随机对照研究
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作者 王昆明 王鑫 +2 位作者 苑炜 张莉 刘晓麟 《首都食品与医药》 2026年第5期36-38,共3页
目的本研究旨在评估450nm蓝激光前列腺汽化剜除术(BVP)治疗前列腺增生(BPH)的疗效及安全性。方法选取2023年4月-2025年3月期间在本院接受治疗的100例BPH患者,按随机方法分为实验组(n=50)和对照组(n=50)。对照组接受钬激光前列腺剜除术,... 目的本研究旨在评估450nm蓝激光前列腺汽化剜除术(BVP)治疗前列腺增生(BPH)的疗效及安全性。方法选取2023年4月-2025年3月期间在本院接受治疗的100例BPH患者,按随机方法分为实验组(n=50)和对照组(n=50)。对照组接受钬激光前列腺剜除术,实验组接受蓝激光前列腺汽化剜除术(BVP)治疗。比较两组尿道功能、前列腺症状、生活质量及并发症发生率。结果干预后,实验组患者的Qmax指标水平高于对照组(P<0.05);干预后,实验组患者的IPSS分数低于对照组,BPH-QOL及IEF-5评分高于对照组(P<0.05);实验组患者的并发症发生率低于对照组(P<0.05)。结论对BPH患者采用BVP治疗可有效提升疗效,改善患者的症状和生活质量,并降低并发症发生率。 展开更多
关键词 450nm蓝激光 前列腺增生 前列腺汽化剜除术 疗效 安全性
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450 nm半导体蓝激光前列腺汽化切除术治疗不停用抗凝药高危良性前列腺增生患者初探
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作者 吴永第 孙家庆 +3 位作者 晁亮 周臣 邱冬 史鹏飞 《现代泌尿外科杂志》 2026年第2期131-134,共4页
目的分析450 nm半导体蓝激光前列腺汽化切除术在不停用抗凝药物的高危良性前列腺增生(BPH)患者治疗中应用的疗效及安全性,以期为此类患者提供安全有效的微创治疗方案。方法选取2023年9月—2024年12月于徐州医科大学附属第三医院泌尿外... 目的分析450 nm半导体蓝激光前列腺汽化切除术在不停用抗凝药物的高危良性前列腺增生(BPH)患者治疗中应用的疗效及安全性,以期为此类患者提供安全有效的微创治疗方案。方法选取2023年9月—2024年12月于徐州医科大学附属第三医院泌尿外科接受450 nm半导体蓝激光前列腺汽化切除术治疗的40例高危BPH患者作为研究对象。根据围手术期是否停用抗凝药物分为两组,其中口服抗凝药物组患者围手术期继续接受口服抗凝药物治疗,停用抗凝药物组患者围手术期停用抗凝药物,每组20例。比较两组患者围手术期指标,术前及术后3个月的国际前列腺症状评分(IPSS)、生活质量评分(QoL)、最大尿流率(Qmax)和残余尿量(PVR)变化。结果口服抗凝药物组与停用抗凝药物组患者的手术时间[(28.83±15.52)min vs.(26.43±14.02)min]、术后留置导尿管时间[(3.04±0.89)d vs.(3.23±1.01)d]、术后膀胱冲洗时间[(27.36±7.54)h vs.(25.46±7.10)h]和术后血红蛋白下降值[(8.08±1.82)g/L vs.(7.56±1.68)g/L]等围手术期指标比较,差异均无统计学意义(P>0.05)。两组患者术后3个月的Qmax高于术前,IPSS、QoL及PVR均明显低于术前,差异均有统计学意义(P<0.05),但两组间术前及术后3个月的IPSS、QoL、Qmax及PVR比较,差异均无统计学意义(P>0.05)。所有患者均未发生尿失禁、大出血等严重并发症。结论450 nm半导体蓝激光前列腺汽化切除术治疗高危BPH患者具有汽化效率高、止血效果好等特点,该术式可显著改善患者的临床症状且安全性高,尤其适用于无法停用抗凝药物的高危BPH患者。 展开更多
关键词 良性前列腺增生 450 nm半导体蓝激光 抗凝药物 前列腺汽化切除术
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强脉冲激光联合红蓝光对痤疮红斑患者红斑指数、黑色素指数及皮肤屏障的影响
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作者 李峰 胡星月 赵艳 《临床医学研究与实践》 2026年第9期83-86,共4页
目的分析强脉冲激光联合红蓝光对痤疮红斑患者红斑指数(EI)、黑色素指数(MI)及皮肤屏障功能的影响。方法选择2024年3月至9月本院收治的112例痤疮红斑患者,依据随机数字表法分为对照组和观察组,各56例。对照组接受红蓝光照射治疗,观察组... 目的分析强脉冲激光联合红蓝光对痤疮红斑患者红斑指数(EI)、黑色素指数(MI)及皮肤屏障功能的影响。方法选择2024年3月至9月本院收治的112例痤疮红斑患者,依据随机数字表法分为对照组和观察组,各56例。对照组接受红蓝光照射治疗,观察组在对照组的基础上联合强脉冲激光治疗。比较两组的临床疗效、EI、MI、皮肤屏障功能、皮损部位炎症因子水平、生活质量、心理状态及不良反应发生情况。结果观察组的治疗总有效率高于对照组(P<0.05)。治疗后,观察组的EI、MI、油脂含量、表皮水分丢失量(TEWL)低于对照组,皮肤含水量高于对照组(P<0.05)。治疗后,观察组的白细胞介素-4(IL-4)、肿瘤坏死因子-α(TNF-α)、干扰素γ(IFN-γ)水平低于对照组(P<0.05)。治疗后,观察组的皮肤病生活质量指数(DLQI)、焦虑自评量表(SAS)、抑郁自评量表(SDS)评分低于对照组(P<0.05)。两组患者的不良反应总发生率无显著差异(P>0.05)。结论强脉冲激光联合红蓝光治疗痤疮红斑效果显著,可显著降低EI、MI,改善患者皮肤屏障功能以及皮损部位炎症因子水平,同时提升患者生活质量、改善心理状态,且安全性较高。 展开更多
关键词 痤疮红斑 强脉冲激光 红蓝光 黑色素指数 皮肤屏障
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450 nm diode laser:A new help in oral surgery 被引量:3
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作者 Carlo Fornaini Jean-Paul Rocca Elisabetta Merigo 《World Journal of Clinical Cases》 SCIE 2016年第9期253-257,共5页
AIM To describe the performance of 450 nm diode laser in oral surgery procedures.METHODS The case described consisted of the removal of a lower lip fibroma through a blue diode laser(λ = 450 nm). RESULTS The efficacy... AIM To describe the performance of 450 nm diode laser in oral surgery procedures.METHODS The case described consisted of the removal of a lower lip fibroma through a blue diode laser(λ = 450 nm). RESULTS The efficacy of this device, even at very low power(1W, CW), allows us to obtain very high intra and postoperative comfort for the patient, even with just topical anaesthesia and without needing suture. The healing process was completed in one week and, during the follow-up, the patient did not report any problems, pain or discomfort even without the consumption of any kind of drugs, such as painkillers and antibiotics. The histological examination performed by the pathologist showed a large area of fibrous connective tissue with some portions of epithelium-connective detachments and a regular incision with very scanty areas of carbonization.CONCLUSION The 450 nm diode laser proved of being very efficient in the oral soft tissue surgical procedures, with no side effects for the patients. 展开更多
关键词 blue laser Advantages ORAL surgery PATIENT SATISFACTION
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蓝激光成像技术微放大分型内镜培训提高内镜医师萎缩性胃炎内镜检出率及其与病理符合度的研究 被引量:1
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作者 陈超 李晨阳 +8 位作者 汪涛 张宁宁 黄福秀 梁志民 徐衍 赵慧 徐忠瑞 李淑玲 殷健 《胃肠病学和肝病学杂志》 2025年第4期512-516,共5页
目的验证蓝激光成像技术微放大分型内镜培训对不同年资内镜医师诊断慢性萎缩性胃炎检出率及准确度的影响。方法将内镜医师分为两组:对照组为未接受蓝激光内镜培训的医师,使用普通白光内镜检查;培训组为接受蓝激光成像技术微放大分型内... 目的验证蓝激光成像技术微放大分型内镜培训对不同年资内镜医师诊断慢性萎缩性胃炎检出率及准确度的影响。方法将内镜医师分为两组:对照组为未接受蓝激光内镜培训的医师,使用普通白光内镜检查;培训组为接受蓝激光成像技术微放大分型内镜培训的医师,使用蓝激光内镜检查。根据内镜操作总数分为低年资内镜医师和高年资内镜医师。选取2017年12月至2018年5月998例慢性胃炎患者由对照组医师使用普通白光内镜检查;2018年4月至2019年8月261例慢性胃炎患者由培训组医师使用蓝激光成像内镜微放大检查(放大倍数20~40倍)。两组医师在内镜检查完成后即刻对受检查患者萎缩与否行内镜预判并留存结果。以病理结果为金指标,计算两组不同年资内镜医师对慢性萎缩性胃炎的检出率及内镜预判与病理诊断的符合度。结果(1)对照组慢性萎缩性胃炎检出率为29.4%,低年资、高年资内镜医师检出率分别为25.3%、36.6%,差异有统计学意义(P<0.05);培训组慢性萎缩性胃炎检出率为50.2%,低年资、高年资内镜医师检出率分别为45.9%、54.8%。(2)对照组内镜预判萎缩性胃炎与病理诊断的符合度为53.8%,低年资、高年资内镜医师与病理诊断的符合度分别为50.5%、59.7%;培训组内镜预判萎缩性胃炎与病理诊断的符合度为68.0%,低年资、高年资内镜医师与病理诊断的符合度分别为64.8%、70.7%。(3)对照组萎缩性胃炎内镜漏诊率为62.3%,低年资、高年资内镜医师内镜漏诊率分别为66.7%、53.2%;培训组萎缩性胃炎内镜漏诊率为19.4%,低年资、高年资内镜医师内镜漏诊率分别为25.8%、13.4%。结论不同年资内镜医师普通白光内镜对慢性萎缩性胃炎的漏诊率均较高,与病理诊断的符合度均较低,尤其是低年资内镜医师更为明显。蓝激光成像技术微放大分型内镜培训对不同年资内镜医师均能显著减少慢性萎缩性胃炎的漏诊率,提高内镜预判与病理诊断的符合度。低年资内镜医师通过蓝激光成像技术微放大分型的内镜培训,对慢性萎缩性胃炎的检出率及与病理的符合度能达到甚至超过未培训的高年资内镜医师。 展开更多
关键词 蓝激光成像技术 微放大分型 慢性萎缩性胃炎 内镜检查 诊断
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前列腺蓝激光汽化术治疗良性前列腺增生的初步临床经验及学习曲线分析 被引量:3
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作者 曹奇峰 邵宁 +1 位作者 崔心刚 康健 《临床泌尿外科杂志》 2025年第3期280-283,共4页
目的:探讨前列腺蓝激光汽化术治疗良性前列腺增生的安全性和有效性,以及评估该技术对不同年资泌尿外科医师的学习曲线。方法:回顾性分析2022年10月—2024年10月在上海交通大学医学院附属新华医院行前列腺蓝激光汽化术84例患者的临床资... 目的:探讨前列腺蓝激光汽化术治疗良性前列腺增生的安全性和有效性,以及评估该技术对不同年资泌尿外科医师的学习曲线。方法:回顾性分析2022年10月—2024年10月在上海交通大学医学院附属新华医院行前列腺蓝激光汽化术84例患者的临床资料。在有完整随访数据的32例患者中,分析术前和术后第1、6、12个月的国际前列腺症状评分、生活质量评分、尿流率、残余尿、手术并发症,以及尿控和性功能的情况,判断该术式的有效性和安全性。并通过手术效率与学习曲线拟合,研究对比新手与资深医生对该技术的适应情况。结果:蓝激光在术后1个月能显著改善前列腺梗阻症状,效果维持1年以上。同时在尿控及性功能保护方面表现优越,手术后未发生尿失禁等严重并发症。对于掌握前列腺增生手术技巧的医生,前列腺蓝激光汽化术的学习曲线为9~11例,初学者17例操作后也能达到成熟期。结论:前列腺蓝激光汽化术具有安全高效、学习曲线短的优势,有望在前列腺增生治疗中得以推广。 展开更多
关键词 450 nm半导体蓝激光 前列腺增生 安全性 有效性 学习曲线
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