To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measur...To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measurement of the endocochlear potential (EP) was established in guinea pigs with gradual ischemia of the cochlea. It was found that occlusions of both common carotid arteries and one of the vertebral arteries produced a minor reduction in CBF with no significant alteration in the EP. When intravenous infusion of ATP induced sharp and severe decreases in CBF, the EP varied only slightly from the baseline in some animals while there were no alteration in others. Furthermore, ATP infusions combined with arterial occlusions caused even more severe declines in CBF and a moderate decrease in the EP. The results indicate that not only does the CBF satisfy the basic needs of the processes of cochlear function, but also has a regulatory mechanism to ensure the normal function of the cochlea in the ischemia condition. It was also found that the changes in the stria vascularis vessels induced by decreases in blood pressure (BP) and heart rates were more severe than those of the spiral ligament vessels. This phenomenon indicated that the stria vascularis vessels were more sensitive to decreases of BP and heart rates.展开更多
Objective: To explore the clinical effect of integrated traditional Chinese and western medicine on vertigo patients with wind-phlegm syndrome. Methods: The clinical statistical analysis of the control group was set t...Objective: To explore the clinical effect of integrated traditional Chinese and western medicine on vertigo patients with wind-phlegm syndrome. Methods: The clinical statistical analysis of the control group was set to explore the curative effect of western medicine and combination of Chinese and western medicine in treating vertigo caused by wind-phlegm disturbance. 100 patients (50 patients in the control group and 50 patients in the experimental group) were selected from our hospital from January 2019 to January 2022. The control group and the experimental group were treated with western medicine and the combination of Chinese and western medicine respectively to explore the curative effect. Results: Through the statistical analysis of the control group and the experimental group, it is concluded that the effective rate of the experimental group treated with combination of Chinese and western medicine is higher than that of the control group (P 0.05). After treatment, the TCD of the two groups was significantly better than that before treatment, and the curative effect of the experimental group was better than that of the control group (P0.05). Conclusion: The curative effect of integrated traditional Chinese and western medicine in treating vertigo caused by wind-phlegm disturbance is better than that of western medicine alone, and the clinical symptoms are relieved and the indexes are optimized, which is worthy of clinical application.展开更多
文摘To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measurement of the endocochlear potential (EP) was established in guinea pigs with gradual ischemia of the cochlea. It was found that occlusions of both common carotid arteries and one of the vertebral arteries produced a minor reduction in CBF with no significant alteration in the EP. When intravenous infusion of ATP induced sharp and severe decreases in CBF, the EP varied only slightly from the baseline in some animals while there were no alteration in others. Furthermore, ATP infusions combined with arterial occlusions caused even more severe declines in CBF and a moderate decrease in the EP. The results indicate that not only does the CBF satisfy the basic needs of the processes of cochlear function, but also has a regulatory mechanism to ensure the normal function of the cochlea in the ischemia condition. It was also found that the changes in the stria vascularis vessels induced by decreases in blood pressure (BP) and heart rates were more severe than those of the spiral ligament vessels. This phenomenon indicated that the stria vascularis vessels were more sensitive to decreases of BP and heart rates.
文摘Objective: To explore the clinical effect of integrated traditional Chinese and western medicine on vertigo patients with wind-phlegm syndrome. Methods: The clinical statistical analysis of the control group was set to explore the curative effect of western medicine and combination of Chinese and western medicine in treating vertigo caused by wind-phlegm disturbance. 100 patients (50 patients in the control group and 50 patients in the experimental group) were selected from our hospital from January 2019 to January 2022. The control group and the experimental group were treated with western medicine and the combination of Chinese and western medicine respectively to explore the curative effect. Results: Through the statistical analysis of the control group and the experimental group, it is concluded that the effective rate of the experimental group treated with combination of Chinese and western medicine is higher than that of the control group (P 0.05). After treatment, the TCD of the two groups was significantly better than that before treatment, and the curative effect of the experimental group was better than that of the control group (P0.05). Conclusion: The curative effect of integrated traditional Chinese and western medicine in treating vertigo caused by wind-phlegm disturbance is better than that of western medicine alone, and the clinical symptoms are relieved and the indexes are optimized, which is worthy of clinical application.
