Background: Cesarean section is now the most common major surgical procedure performed on women worldwide. With the increasing numbers of cesarean sections, there is the need to utilize evidence based techniques to op...Background: Cesarean section is now the most common major surgical procedure performed on women worldwide. With the increasing numbers of cesarean sections, there is the need to utilize evidence based techniques to optimize outcomes and minimize complications. We hypothesize that omission of the bladder flap in both primary and repeat cesarean sections will be associated with shorter operating time without a significant increase in intraoperative and postoperative complications. Methods: 550 patients were enrolled in the study. They were randomly allocated in the 2 groups to evaluate the effects of cancelling the bladder dissection. Results: Significant reduction of the total operating time (p = 0.01), skin to delivery time (p = 0.02) and micro-hematuria (p = 0.01) in group with bladder omission. Long term result: Including more bladder adhesion and fibrosis in the cases with bladder dissection. Conclusions: Omission of the bladder dissection achieved short-term advantages as regards reduction of operating time, incision-delivery duration and decreased blood loss as well as long-term effects include different in the bladder adhesion.展开更多
Background: This study aims to evaluate the effects of omission of the bladder flap formation at primary and repeat lower segment CS. Patients and Methods: The current study was randomized controlled trial conducted i...Background: This study aims to evaluate the effects of omission of the bladder flap formation at primary and repeat lower segment CS. Patients and Methods: The current study was randomized controlled trial conducted in Women Health Hospital, Assiut University, Egypt between March 2017 and May 2018 (ClinicalTrial.gov NCT03016273). Patients were divided into: Non bladder flap group: Uterine incision made 1 cm above the vesico-uterine reflection without incision and dissection of the bladder peritoneum and bladder flap group: Standard cesarean section technique with incision and dissection of a bladder flap prior to uterine incision. Results: The study included 150 patients (75 in each arm). The most common indication for CS in both groups was repeated CS. Non-bladder flap group, compared with flap group, showed shorter skin-incision to delivery time and total operative time, and significantly lower mean estimated blood loss and postoperative pain score. Non-bladder flap group, compared with flap group, was more likely to show postoperative microhematuria. The two groups required approximately the same time for post-operative defecation. Conclusion: Omission of bladder flap formation during CS is associated with shorter operative time, less blood loss, less postoperative pain and lower incidence of postoperative hematuria.展开更多
A 60-year-old male was diagnosed with rectal cancer with peripheral lymph node metastasis two years prior and underwent three cycles of the XELOX(capecitabine plus oxaliplatin)chemotherapy regimen,followed by radiothe...A 60-year-old male was diagnosed with rectal cancer with peripheral lymph node metastasis two years prior and underwent three cycles of the XELOX(capecitabine plus oxaliplatin)chemotherapy regimen,followed by radiotherapy and a successful laparoscopic radical resection of the rectal carcinoma,with a postoperative pathological stage of T4N3M0.展开更多
目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收...目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收集肿瘤大小、病理分级、分期、肾功能水平、住院时间等数据并结合患者生存情况进行统计学分析。结果:共有39例患者进行了手术治疗,包括Boari膀胱肌瓣术16例,输尿管癌根治术23例。中位随访时间为53个月(10~84个月),18名患者死亡,其中Boari膀胱肌瓣术组死亡6例,输尿管癌根治术组死亡12例。2组的5年无膀胱癌复发存活率分别为63%和59%(P>0.05),5年肿瘤特异性生存率分别为73.8%和73.5%(P>0.05),5年生存率分别为61%和57%(P>0.05),总体存活率分别为64.8%和58.1%(P>0.05)。2组间术前肾功能无明显差异[肌酐清除率57(32~104)mL/min vs 55(30~102)mL/min,P>0.05],术后Boari膀胱肌瓣术组肾功能优于输尿管癌根治术组[肌酐清除率55(35~102)mL/min vs 43(30~89)mL/min,P<0.05]。Cox比例风险回归模型多因素分析发现肾功能水平、肿瘤大小、病理分级和病理分期是影响肿瘤患者总生存期的独立因素(P<0.05),肿瘤越大、病理分级和分期越高,患者死亡风险越大,而术后高水平的肌酐清除率可以降低疾病的死亡风险。结论:Boari膀胱肌瓣术治疗中下段输尿管癌是可行的方式。相比输尿管癌根治术,Boari膀胱肌瓣术治疗后的生存率并无明显差别,而且能保护患者肾功能。展开更多
文摘Background: Cesarean section is now the most common major surgical procedure performed on women worldwide. With the increasing numbers of cesarean sections, there is the need to utilize evidence based techniques to optimize outcomes and minimize complications. We hypothesize that omission of the bladder flap in both primary and repeat cesarean sections will be associated with shorter operating time without a significant increase in intraoperative and postoperative complications. Methods: 550 patients were enrolled in the study. They were randomly allocated in the 2 groups to evaluate the effects of cancelling the bladder dissection. Results: Significant reduction of the total operating time (p = 0.01), skin to delivery time (p = 0.02) and micro-hematuria (p = 0.01) in group with bladder omission. Long term result: Including more bladder adhesion and fibrosis in the cases with bladder dissection. Conclusions: Omission of the bladder dissection achieved short-term advantages as regards reduction of operating time, incision-delivery duration and decreased blood loss as well as long-term effects include different in the bladder adhesion.
文摘Background: This study aims to evaluate the effects of omission of the bladder flap formation at primary and repeat lower segment CS. Patients and Methods: The current study was randomized controlled trial conducted in Women Health Hospital, Assiut University, Egypt between March 2017 and May 2018 (ClinicalTrial.gov NCT03016273). Patients were divided into: Non bladder flap group: Uterine incision made 1 cm above the vesico-uterine reflection without incision and dissection of the bladder peritoneum and bladder flap group: Standard cesarean section technique with incision and dissection of a bladder flap prior to uterine incision. Results: The study included 150 patients (75 in each arm). The most common indication for CS in both groups was repeated CS. Non-bladder flap group, compared with flap group, showed shorter skin-incision to delivery time and total operative time, and significantly lower mean estimated blood loss and postoperative pain score. Non-bladder flap group, compared with flap group, was more likely to show postoperative microhematuria. The two groups required approximately the same time for post-operative defecation. Conclusion: Omission of bladder flap formation during CS is associated with shorter operative time, less blood loss, less postoperative pain and lower incidence of postoperative hematuria.
文摘A 60-year-old male was diagnosed with rectal cancer with peripheral lymph node metastasis two years prior and underwent three cycles of the XELOX(capecitabine plus oxaliplatin)chemotherapy regimen,followed by radiotherapy and a successful laparoscopic radical resection of the rectal carcinoma,with a postoperative pathological stage of T4N3M0.
文摘目的:研究针对中下段输尿管癌患者的保肾治疗策略中采用Boari膀胱肌瓣术治疗的疗效。方法:回顾性分析湘雅二医院泌尿外科从2002年7月至2007年6月采用Boari膀胱肌瓣术和输尿管癌根治术治疗中下段输尿管癌患者的临床资料及其随访情况,收集肿瘤大小、病理分级、分期、肾功能水平、住院时间等数据并结合患者生存情况进行统计学分析。结果:共有39例患者进行了手术治疗,包括Boari膀胱肌瓣术16例,输尿管癌根治术23例。中位随访时间为53个月(10~84个月),18名患者死亡,其中Boari膀胱肌瓣术组死亡6例,输尿管癌根治术组死亡12例。2组的5年无膀胱癌复发存活率分别为63%和59%(P>0.05),5年肿瘤特异性生存率分别为73.8%和73.5%(P>0.05),5年生存率分别为61%和57%(P>0.05),总体存活率分别为64.8%和58.1%(P>0.05)。2组间术前肾功能无明显差异[肌酐清除率57(32~104)mL/min vs 55(30~102)mL/min,P>0.05],术后Boari膀胱肌瓣术组肾功能优于输尿管癌根治术组[肌酐清除率55(35~102)mL/min vs 43(30~89)mL/min,P<0.05]。Cox比例风险回归模型多因素分析发现肾功能水平、肿瘤大小、病理分级和病理分期是影响肿瘤患者总生存期的独立因素(P<0.05),肿瘤越大、病理分级和分期越高,患者死亡风险越大,而术后高水平的肌酐清除率可以降低疾病的死亡风险。结论:Boari膀胱肌瓣术治疗中下段输尿管癌是可行的方式。相比输尿管癌根治术,Boari膀胱肌瓣术治疗后的生存率并无明显差别,而且能保护患者肾功能。
