Opisthorchiasis caused by Opistorchis viverrini(O.viverrini) remains as medically important problem in Thailand especially in the north-eastern part.Infection with this parasite can lead to cholangiocarcinoma improvem...Opisthorchiasis caused by Opistorchis viverrini(O.viverrini) remains as medically important problem in Thailand especially in the north-eastern part.Infection with this parasite can lead to cholangiocarcinoma improvement.The highest prevalence of O.viverrini infection has been found in the Northeast Thailand and is associated with the high incidence rate of cholangiocarcinoma.To complete the life cycle of 0.viverrini,the freshwater snails namely Bithynia funiculata,Bithynia siamensu siamensis and Bithynia siamensis goniomphalos(B.s.goniomphalos) are required to serve as the first intermediate host.Within these snails group,B.s.goniomphalos is distributed concisely in northeast Thailand and acts as the majority snail that transmitted the opisthorchiasis in this region.This study described the information of B.s.goniomphalos which research are needed for understanding the biology,distribution,transmission and factors influencing on the infection of the snail vector of this carcinogenic parasite.展开更多
目的分析环境因子对赤豆螺分布的影响,预估当前和2050年代表性浓度路径(RCP)气候情景下赤豆螺在我国的分布范围。方法在中国知网、万方数据知识服务平台、维普中文科技期刊数据库、中国生物医学文献数据库及PubMed、Web of Science英文...目的分析环境因子对赤豆螺分布的影响,预估当前和2050年代表性浓度路径(RCP)气候情景下赤豆螺在我国的分布范围。方法在中国知网、万方数据知识服务平台、维普中文科技期刊数据库、中国生物医学文献数据库及PubMed、Web of Science英文数据库中检索国内外公开发表的赤豆螺相关文献,检索日期为2000年1月1日至2021年7月15日,从文献中提取赤豆螺在我国的分布点信息,结合环境因子数据,运用最大熵模型(MaxEnt)分析环境因子对赤豆螺分布的影响,并预估赤豆螺在我国的适生区范围。结果各环境因子中,海拔、最干月降水量、昼夜温差月均值和归一化水体指数对赤豆螺分布的影响较大,贡献率分别为30.30%、26.90%、12.40%和12.20%。当前气候条件下,我国赤豆螺的适生区面积为244.23万km^(2),其中,高适生区35.60万km^(2),中适生区70.57万km^(2),低适生区138.06万km^(2)。RCP 4.5气候情景下,2050年赤豆螺在我国的适生区范围将向北扩大,适生区面积新增45.05万km^(2)。结论赤豆螺在我国的分布范围受海拔影响较大,未来气候变化将使我国赤豆螺的分布范围扩大。展开更多
Background:Prevalence of Opisthorchis viverrini,Schistosoma mekongi and soil-transmitted helminths(STH)remains high in Lao People’s Democratic Republic(Lao PDR),despite control efforts including mass-drug administrat...Background:Prevalence of Opisthorchis viverrini,Schistosoma mekongi and soil-transmitted helminths(STH)remains high in Lao People’s Democratic Republic(Lao PDR),despite control efforts including mass-drug administration,education and communication campaigns.New approaches are required to advance helminth control.Methods:An ecohealth study was conducted on two Mekong islands in Southern Laos.Demographic and behavioural data were collected by questionnaire.Human and animal reservoir stools were examined.Bithynia spp.and Neotricula aperta snails were examined using shedding.Fresh water fish were examined using digestion technique.Multivariate random-effects analysis was used to find risk factors associated with helminth infections.Results:Human infection rates with O.viverrini,hookworm,S.mekongi,Trichuris trichiura,Ascaris lumbricoides and Taenia spp.were 60.7%,44.1%,22.2%,4.1%,0.6%and 0.1%,respectively.Heavy intensity infections were 4.2%,3.6%and 1.8%for O.viverrini,S.mekongi and hookworm,respectively.O.viverrini and S.mekongi infection rates among dogs and cats were 25.0%and 14.7%,respectively.Of the cats tested,53.1%were infected with O.viverrini.Prevalence of O.viverrini and S.mekongi in snails was 0.3%and 0.01%,respectively.Overall prevalence of O.viverrini infection in fresh water fish was 26.9%,with the highest infection rates occurring in Hampala dispa(87.1%),Cyclocheilichthys apogon(85.7%)and Puntius brevis(40.0%).Illiteracy and lower socioeconomic status increased the risk of O.viverrini infection,while those aged 10-16 years and possessing latrines at home were less likely to be infected.Household dogs and cats that consumed raw fish were significantly and positively associated with O.viverrini infection of the household members.For S.mekongi,children under 9 years old were exposed significantly to this infection,compared to older age groups.Conclusions:There is a pressing need to design and implement an integrated helminth control intervention on the Mekong Islands in southern Lao PDR.Given the highly dynamic transmission of O.viverrini,S.mekongi,STH and extended multiparasitism,annual mass-drug administration is warranted along with environmental modifications,health education and improved access to clean water and adequate sanitation to consolidate morbidity control and move towards elimination.Trail registration number:Our findings presented here are from a cross-sectional study,therefore,it has not been registered.展开更多
文摘Opisthorchiasis caused by Opistorchis viverrini(O.viverrini) remains as medically important problem in Thailand especially in the north-eastern part.Infection with this parasite can lead to cholangiocarcinoma improvement.The highest prevalence of O.viverrini infection has been found in the Northeast Thailand and is associated with the high incidence rate of cholangiocarcinoma.To complete the life cycle of 0.viverrini,the freshwater snails namely Bithynia funiculata,Bithynia siamensu siamensis and Bithynia siamensis goniomphalos(B.s.goniomphalos) are required to serve as the first intermediate host.Within these snails group,B.s.goniomphalos is distributed concisely in northeast Thailand and acts as the majority snail that transmitted the opisthorchiasis in this region.This study described the information of B.s.goniomphalos which research are needed for understanding the biology,distribution,transmission and factors influencing on the infection of the snail vector of this carcinogenic parasite.
文摘目的分析环境因子对赤豆螺分布的影响,预估当前和2050年代表性浓度路径(RCP)气候情景下赤豆螺在我国的分布范围。方法在中国知网、万方数据知识服务平台、维普中文科技期刊数据库、中国生物医学文献数据库及PubMed、Web of Science英文数据库中检索国内外公开发表的赤豆螺相关文献,检索日期为2000年1月1日至2021年7月15日,从文献中提取赤豆螺在我国的分布点信息,结合环境因子数据,运用最大熵模型(MaxEnt)分析环境因子对赤豆螺分布的影响,并预估赤豆螺在我国的适生区范围。结果各环境因子中,海拔、最干月降水量、昼夜温差月均值和归一化水体指数对赤豆螺分布的影响较大,贡献率分别为30.30%、26.90%、12.40%和12.20%。当前气候条件下,我国赤豆螺的适生区面积为244.23万km^(2),其中,高适生区35.60万km^(2),中适生区70.57万km^(2),低适生区138.06万km^(2)。RCP 4.5气候情景下,2050年赤豆螺在我国的适生区范围将向北扩大,适生区面积新增45.05万km^(2)。结论赤豆螺在我国的分布范围受海拔影响较大,未来气候变化将使我国赤豆螺的分布范围扩大。
基金We are grateful to the International Development Research CentreForeign Affairs,Trade and Development Canada(through the Global Health Research Initiative)the Australian Agency for International Development for funding support。
文摘Background:Prevalence of Opisthorchis viverrini,Schistosoma mekongi and soil-transmitted helminths(STH)remains high in Lao People’s Democratic Republic(Lao PDR),despite control efforts including mass-drug administration,education and communication campaigns.New approaches are required to advance helminth control.Methods:An ecohealth study was conducted on two Mekong islands in Southern Laos.Demographic and behavioural data were collected by questionnaire.Human and animal reservoir stools were examined.Bithynia spp.and Neotricula aperta snails were examined using shedding.Fresh water fish were examined using digestion technique.Multivariate random-effects analysis was used to find risk factors associated with helminth infections.Results:Human infection rates with O.viverrini,hookworm,S.mekongi,Trichuris trichiura,Ascaris lumbricoides and Taenia spp.were 60.7%,44.1%,22.2%,4.1%,0.6%and 0.1%,respectively.Heavy intensity infections were 4.2%,3.6%and 1.8%for O.viverrini,S.mekongi and hookworm,respectively.O.viverrini and S.mekongi infection rates among dogs and cats were 25.0%and 14.7%,respectively.Of the cats tested,53.1%were infected with O.viverrini.Prevalence of O.viverrini and S.mekongi in snails was 0.3%and 0.01%,respectively.Overall prevalence of O.viverrini infection in fresh water fish was 26.9%,with the highest infection rates occurring in Hampala dispa(87.1%),Cyclocheilichthys apogon(85.7%)and Puntius brevis(40.0%).Illiteracy and lower socioeconomic status increased the risk of O.viverrini infection,while those aged 10-16 years and possessing latrines at home were less likely to be infected.Household dogs and cats that consumed raw fish were significantly and positively associated with O.viverrini infection of the household members.For S.mekongi,children under 9 years old were exposed significantly to this infection,compared to older age groups.Conclusions:There is a pressing need to design and implement an integrated helminth control intervention on the Mekong Islands in southern Lao PDR.Given the highly dynamic transmission of O.viverrini,S.mekongi,STH and extended multiparasitism,annual mass-drug administration is warranted along with environmental modifications,health education and improved access to clean water and adequate sanitation to consolidate morbidity control and move towards elimination.Trail registration number:Our findings presented here are from a cross-sectional study,therefore,it has not been registered.
