A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3 -diindolyloxindole derivatives from the reaction of indoles with various ald...A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3 -diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported.The significant features of this procedure are high yields of the products,mild reaction,solvent-free condition and non-toxicity of the catalyst.展开更多
Oxone （3.5 mol%） was found to be an effective catalyst for the condensation reactions of indoles with aldehydes to afford bisindolylmethanes in good to excellent yields within 10-30min. The method is simple and econ...Oxone （3.5 mol%） was found to be an effective catalyst for the condensation reactions of indoles with aldehydes to afford bisindolylmethanes in good to excellent yields within 10-30min. The method is simple and economic. The catalyst is found to be recyclable.展开更多
Stable and non-hygroscopic silica gel supported aluminium chloride（SiO_2-AlCl_3）,which is prepared easily from cheap and commercially available compounds was found to be an environmentally friendly heterogeneous cat...Stable and non-hygroscopic silica gel supported aluminium chloride（SiO_2-AlCl_3）,which is prepared easily from cheap and commercially available compounds was found to be an environmentally friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford bis-indolylmethanes at room temperature under solvent-free conditions.The catalyst can be reused up to five times after simple washing with ether.展开更多
基金support of this work from the Research Council of Mazandaran University
文摘A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3 -diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported.The significant features of this procedure are high yields of the products,mild reaction,solvent-free condition and non-toxicity of the catalyst.
文摘Oxone （3.5 mol%） was found to be an effective catalyst for the condensation reactions of indoles with aldehydes to afford bisindolylmethanes in good to excellent yields within 10-30min. The method is simple and economic. The catalyst is found to be recyclable.
基金the partial support of this study by the Shahrekord University and the Islamic Azad University,Shahr-e-Rey branch Research Council
文摘Stable and non-hygroscopic silica gel supported aluminium chloride（SiO_2-AlCl_3）,which is prepared easily from cheap and commercially available compounds was found to be an environmentally friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford bis-indolylmethanes at room temperature under solvent-free conditions.The catalyst can be reused up to five times after simple washing with ether.
