The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human ...The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human Genome Project(HGP)in completing the“1%task”to independently accomplishing the super-hybrid rice genome and other several national and international genome projects,BIG has made tremendous contributions in genomics research and development in China.In 2024,bearing great ambition and responsibility,BIG is transformed to the China National Center for Bioinformation(CNCB),aiming to become a global hub in bioinformatics big data services,innovation,and entrepreneurship.With the completion of its new infrastructure in 2027,CNCB is looking into a brighter future.展开更多
[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dis...[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dismutase(SOD)and peroxidase(POD)and the content changes of malondialdehyde(MDA)in the leaves of seedlings were determined.A control group(distilled water)and three treatment groups(NaCl concentrations of 1,2 and 3 mmol/L)were set up.When the wheat seedlings grew to two leaves and one heart,they should be treated with different concentrations of NaCl solution(the wheat seedlings grew uniformly,and 20 ml of each NaCl concentration was used for treatment of wheat).When the wheat seedlings grew to four leaves and one heart under stress,samples were taken separately,once every 2 d,for three times,with 5 g of leaves each time.The SOD and POD activities and MDA content of seedlings in the control group and treatment groups were determined,and related protein sequences were analyzed by bioinformatics,including signal peptide prediction,transmembrane domain prediction,phosphorylation prediction and protein structure prediction.[Results]Under NaCl stress,the growth rates of seedling length and root length of wheat decreased obviously,and SOD and POD in leaves decreased,while the MDA content in leaves after treatment increased compared with the control group.SOD had no signal peptide,while POD had signal peptides and a transmembrane region.SOD and POD were different in terms of secondary and tertiary structures and the number of phosphorylation sites.[Conclusions]These results lays a solid theoretical foundation and application prospect for the study on salt tolerance mechanism of wheat seedlings in the later stage.展开更多
The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equ...The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equipped with the most advanced computational techniques and supported by the latest biological research, has emerged for this purpose. Some recent information on the developing bioinformatics, associated with the uniform resource location addresses of those available resource sites that support hyper-text or general file transfer proto-展开更多
文摘The Beijing Institute of Genomics(BIG)of the Chinese Academy of Sciences,as the leading Institute in Genomics,has walked through 20 year’s journey since being founded in November 2003.From participating in the Human Genome Project(HGP)in completing the“1%task”to independently accomplishing the super-hybrid rice genome and other several national and international genome projects,BIG has made tremendous contributions in genomics research and development in China.In 2024,bearing great ambition and responsibility,BIG is transformed to the China National Center for Bioinformation(CNCB),aiming to become a global hub in bioinformatics big data services,innovation,and entrepreneurship.With the completion of its new infrastructure in 2027,CNCB is looking into a brighter future.
文摘[Objectives]This study was conducted to improve crop yield and select excellent wheat varieties.[Methods]Wheat seedlings were treated with different concentrations of NaCl solution,and the activities of superoxide dismutase(SOD)and peroxidase(POD)and the content changes of malondialdehyde(MDA)in the leaves of seedlings were determined.A control group(distilled water)and three treatment groups(NaCl concentrations of 1,2 and 3 mmol/L)were set up.When the wheat seedlings grew to two leaves and one heart,they should be treated with different concentrations of NaCl solution(the wheat seedlings grew uniformly,and 20 ml of each NaCl concentration was used for treatment of wheat).When the wheat seedlings grew to four leaves and one heart under stress,samples were taken separately,once every 2 d,for three times,with 5 g of leaves each time.The SOD and POD activities and MDA content of seedlings in the control group and treatment groups were determined,and related protein sequences were analyzed by bioinformatics,including signal peptide prediction,transmembrane domain prediction,phosphorylation prediction and protein structure prediction.[Results]Under NaCl stress,the growth rates of seedling length and root length of wheat decreased obviously,and SOD and POD in leaves decreased,while the MDA content in leaves after treatment increased compared with the control group.SOD had no signal peptide,while POD had signal peptides and a transmembrane region.SOD and POD were different in terms of secondary and tertiary structures and the number of phosphorylation sites.[Conclusions]These results lays a solid theoretical foundation and application prospect for the study on salt tolerance mechanism of wheat seedlings in the later stage.
文摘The accumulation of the large amount of biological data concerning with gene and protein research has proposed that it is necessary to abstract the biological significance from these data. Then the bioinformatics, equipped with the most advanced computational techniques and supported by the latest biological research, has emerged for this purpose. Some recent information on the developing bioinformatics, associated with the uniform resource location addresses of those available resource sites that support hyper-text or general file transfer proto-
