Dear Editor： Pergularia daemia Forsk （Asclepiadaceae） is a perennial twining herb commonly known as veliparuthi in Tamil. The plant has anthelmintic, laxative, antidiabetic, hepatoprotective and anti-inflammatory ...Dear Editor： Pergularia daemia Forsk （Asclepiadaceae） is a perennial twining herb commonly known as veliparuthi in Tamil. The plant has anthelmintic, laxative, antidiabetic, hepatoprotective and anti-inflammatory activities. The pharmacological properties of this plant come from bioactive phytochemicals such as alkaloids, triterpenes, saponins and flavonoids. Phytochemically, the plant has been investigated for the presence of cardenolides, alkaloids, saponins and steroidal compoundst. In the present study, we developed a rapid method for identification and quantitative determination of putative phyto compounds in the crude extracts of ethyl acetate and methanol from whole plant of Pergularia daemia.展开更多
An excess of reactive oxygen species（ROS）leads to a variety of chronic health problems.As potent antioxidants,marine bioactive extracts containing oligosaccharides and peptides have been extensively studied.Recently...An excess of reactive oxygen species（ROS）leads to a variety of chronic health problems.As potent antioxidants,marine bioactive extracts containing oligosaccharides and peptides have been extensively studied.Recently,there is a growing interest in protein-polysaccharide complexes because of their potential uses in pharmaceutical and food industries.However,only few studies are available on the antioxidant activities of such complexes,in terms of their ROS scavenging capability.In this study,we combined and superoxide radicals,and to evaluate the influences on the activities of superoxide dismutase（SOD）,glutathione peroxidase（GSH-Px）and the level of malondialdehyde（MDA）in UV-induced photoaging models.The results indicated that the antioxidant activities of all the complexes were stronger than those of their individual components.Among the 11 complexes tested,two complexes,namely MA1000＋CP and κ-ca3000＋CP,turned out to be highly effective antioxidants.Although the detailed mechanisms of this improved scavenging ability are not fully understood,this work provides insights into the design of highly efficient peptide-oligosaccharide complexes for potential applications in pharmaceutical,cosmetics and food industries.展开更多
The study determined the best extraction method for phenolic compounds(rutin,catechin,epicatechin,naringenin,neochlorogenic acid,and rosmarinic acid)in the New Zealand damson plums.Accelerated solvent extraction(ASE)u...The study determined the best extraction method for phenolic compounds(rutin,catechin,epicatechin,naringenin,neochlorogenic acid,and rosmarinic acid)in the New Zealand damson plums.Accelerated solvent extraction(ASE)using ethanol and water was used to evaluate the solvent efficacy.Further comparisons were made among ASE,ultrasound-assisted extraction(UAE),enzyme-assisted extraction(EAE),and a combined method(E+UAE)using water as the solvent.The findings showed that ASE for 40 min was the most effective method for extracting phenolic compounds(1.76 mg gallic acid equivalent/g)compared to other methods(UAE=1.17,EAE=1.3,and E+UAE=1.45 mg/g).The ASE method also resulted in an extract with a higher antioxidant activity than other methods.The extraction time over 40 min decreased the yield regardless of the solvent used.Therefore,the ASE extraction method for 40 min is recommended as the best method for extraction of phenolic compounds from the New Zealand damson plums.展开更多
Key for worldwide acceptance of Traditional Chinese Medicine(TCM)is the ability to provide scientific evidence combined with a quality control system based on the bioactive ingredients.Modern scientific technology too...Key for worldwide acceptance of Traditional Chinese Medicine(TCM)is the ability to provide scientific evidence combined with a quality control system based on the bioactive ingredients.Modern scientific technology tools are now available to accomplish standardization of TCM products in order to achieve a high level of efficacy and safety,enhancing the introduction into the展开更多
文摘Dear Editor： Pergularia daemia Forsk （Asclepiadaceae） is a perennial twining herb commonly known as veliparuthi in Tamil. The plant has anthelmintic, laxative, antidiabetic, hepatoprotective and anti-inflammatory activities. The pharmacological properties of this plant come from bioactive phytochemicals such as alkaloids, triterpenes, saponins and flavonoids. Phytochemically, the plant has been investigated for the presence of cardenolides, alkaloids, saponins and steroidal compoundst. In the present study, we developed a rapid method for identification and quantitative determination of putative phyto compounds in the crude extracts of ethyl acetate and methanol from whole plant of Pergularia daemia.
基金funded by the National High Technology Research and Development Program of China 863 Program Grant (2001AA620405)
文摘An excess of reactive oxygen species（ROS）leads to a variety of chronic health problems.As potent antioxidants,marine bioactive extracts containing oligosaccharides and peptides have been extensively studied.Recently,there is a growing interest in protein-polysaccharide complexes because of their potential uses in pharmaceutical and food industries.However,only few studies are available on the antioxidant activities of such complexes,in terms of their ROS scavenging capability.In this study,we combined and superoxide radicals,and to evaluate the influences on the activities of superoxide dismutase（SOD）,glutathione peroxidase（GSH-Px）and the level of malondialdehyde（MDA）in UV-induced photoaging models.The results indicated that the antioxidant activities of all the complexes were stronger than those of their individual components.Among the 11 complexes tested,two complexes,namely MA1000＋CP and κ-ca3000＋CP,turned out to be highly effective antioxidants.Although the detailed mechanisms of this improved scavenging ability are not fully understood,this work provides insights into the design of highly efficient peptide-oligosaccharide complexes for potential applications in pharmaceutical,cosmetics and food industries.
基金Foot Steps Limited(Karamu,Hastings,New Zealand)for providing the samples and financial support for the successful completion of this project-Without their help and supportThe New Zealand High-Value Nutrition National Science Challenge(New Zealand)also supported the previous phase of this work.
文摘The study determined the best extraction method for phenolic compounds(rutin,catechin,epicatechin,naringenin,neochlorogenic acid,and rosmarinic acid)in the New Zealand damson plums.Accelerated solvent extraction(ASE)using ethanol and water was used to evaluate the solvent efficacy.Further comparisons were made among ASE,ultrasound-assisted extraction(UAE),enzyme-assisted extraction(EAE),and a combined method(E+UAE)using water as the solvent.The findings showed that ASE for 40 min was the most effective method for extracting phenolic compounds(1.76 mg gallic acid equivalent/g)compared to other methods(UAE=1.17,EAE=1.3,and E+UAE=1.45 mg/g).The ASE method also resulted in an extract with a higher antioxidant activity than other methods.The extraction time over 40 min decreased the yield regardless of the solvent used.Therefore,the ASE extraction method for 40 min is recommended as the best method for extraction of phenolic compounds from the New Zealand damson plums.
文摘Key for worldwide acceptance of Traditional Chinese Medicine(TCM)is the ability to provide scientific evidence combined with a quality control system based on the bioactive ingredients.Modern scientific technology tools are now available to accomplish standardization of TCM products in order to achieve a high level of efficacy and safety,enhancing the introduction into the
