AIM:To explore the effect of visual perception learning software training(VPT)on binocular visual function reconstruction in children with intermittent exotropia after strabismus surgery.METHODS:Ninety children with i...AIM:To explore the effect of visual perception learning software training(VPT)on binocular visual function reconstruction in children with intermittent exotropia after strabismus surgery.METHODS:Ninety children with intermittent exotropia admitted to our hospital from June 2018 to December 2018 were included,and randomly divided into VPT and control groups.Children in the control group received basic binocular vision training,while those in the VPT group received VPT after strabismus surgery.Tertiary visual function,visual perception function,Newcastle Control Score(NCS),and ocular position retraction rate were compared at 3 and 12mo after the surgery.RESULTS:At 3 and 12mo after the surgery,the proportion of simultaneous perception,binocular fusion version and binocular stereo vision in the VPT group was conspicuously higher than that in the control group(P<0.05).After the vision training,the binocular visual perception functions of children in both groups were significantly improved compared with that before training(P<0.05).Interestingly,the grating sharpness,texture perception and texture motion perception in the VPT group were dramatically better than control group(P<0.01).The NCS in the VPT group was significantly lower than that in the control group(P<0.05).The ocular position retraction rate in the VPT group was significantly lower than that in the control group at 12mo(8.89%vs 26.67%,P=0.03).CONCLUSION:VPT effectively promotes binocular visual function reconstruction in intermittent exotropia children after strabismus surgery and reduces the strabismus severity and ocular position retraction rate.展开更多
Objective To compare the perceived eye position,Titmus and stereopsis function across various types of anisometropia to identify differences in binocular visual function.Methods This study included 204 anisometropic p...Objective To compare the perceived eye position,Titmus and stereopsis function across various types of anisometropia to identify differences in binocular visual function.Methods This study included 204 anisometropic patients(observation group,interocular spherical equivalent difference≥1.5D or cylindrical≥1.0D)and 57 non-anisometropic controls(interocular differences<1.5D spherical or<1.0D cylindrical).Participants were initially stratified based on documented amblyopia history(94 with vs.110 without),followed by further subgrouping of the observation group into hyperopic,myopic,and astigmatic anisometropia types for comparative analysis with controls.Standardized assessments comprised best-corrected visual acuity(BCVA,logMAR),cycloplegic refraction,Titmus near stereopsis(arcsec),binocular perceptual eye position(PEP)deviation,and three-order stereopsis thresholds measured via a computerized binocular vision assessment system.Statistical analysis adhered to CONSORT guidelines(SPSS v26.0,α〓〓=〓〓0.05).Results(1)No significant differences were observed between patients with documented amblyopia history and those without regarding equivalent spherical lens difference,horizontal/vertical PEP,three-order stereopsis,or Titmus test results.(2)The control group demonstrated superior vertical PEP,three-order stereopsis,and Titmus performance compared to all anisometropia subgroups(myopic,hypermetropic,and astigmatic;P〓〓<0.05),though horizontal PEP showed no significant variation(P〓〓>0.05).(3)While Titmus results showed no difference between astigmatic and myopic anisometropia groups(P〓〓=〓〓0.72),significant differences existed among other groups(P<0.05).Notably,the hyperopic anisometropia group exhibited the poorest normal rates for vertical PEP,Titmus,and three-order stereopsis among all groups(P〓〓<0.001).Additionally,the astigmatism group outperformed both myopia and hypermetropia groups in 0-order and 1-order stereopsis(P〓〓<0.05).Conclusions The study revealed no significant difference in visual function between anisometropic amblyopia patients who achieved normal BCVA(≤0.0 LogMAR)and non-amblyopic anisometropic controls.However,all forms of anisometropia demonstrated varying degrees of impairment to binocular fusion and stereopsis,with hypermetropic anisometropia showing the most pronounced deficits,particularly in near stereopsis.Notably,vertical PEP instability may contribute to the progression of hyperopic anisometropia.展开更多
AIM: To investigate the effects of micro-injection of botulinum toxin A(BTXA) on acute acquired comitant esotropia(AACE). METHODS: A total of 33 AACE patients who underwent BTXA micro-injection at Renmin Hospital of W...AIM: To investigate the effects of micro-injection of botulinum toxin A(BTXA) on acute acquired comitant esotropia(AACE). METHODS: A total of 33 AACE patients who underwent BTXA micro-injection at Renmin Hospital of Wuhan University from September 1^(st), 2019 to July 1^(st), 2021 were retrospective analyzed. Esotropia, eye alignment, stereopsis, and complications were examined at baseline(except complications), 1wk, 1, 3, and 6mo after injection. RESULTS: The average angle of deviation before injection was(+20.24±6.80)^(Δ) at near and(+24.76±6.43)^(Δ) at distance, while(+5.15±5.85)^(Δ) at near and(+7.30±6.17)^(Δ) at distance 6mo after treatment(P<0.05). Six months after injection, the stereopsis of patients had improved. The number of patients having no stereopsis(>800 seconds of arc) decreased from 11 to 3. The number of patients having peripheral stereopsis(300-800 seconds of arc), macular stereopsis(70-200 seconds of arc) and central concave stereopsis(≤60 seconds of arc) increased from 10 to 11, 10 to 12, and 2 to 7, respectively. At the follow-ups at 1wk, 1, 3, and 6mo after injection, success rates were 96.97%, 96.97%, 93.94% and 87.88%, respectively. One week after injection, two patients(6.07%) showed subconjunctival hemorrhage;three patients(9.09%) showed limited eye movement and one patient(3.03%) showed mild vertical strabismus. All the symptoms disappeared by the final follow-up.CONCLUSION: Micro-injection of BTXA can reduce diplopia and improve binocular vision function of AACE patients. Furthermore, the operation is relatively safe with few complications, making it an ideal treatment modality for AACE.展开更多
文摘AIM:To explore the effect of visual perception learning software training(VPT)on binocular visual function reconstruction in children with intermittent exotropia after strabismus surgery.METHODS:Ninety children with intermittent exotropia admitted to our hospital from June 2018 to December 2018 were included,and randomly divided into VPT and control groups.Children in the control group received basic binocular vision training,while those in the VPT group received VPT after strabismus surgery.Tertiary visual function,visual perception function,Newcastle Control Score(NCS),and ocular position retraction rate were compared at 3 and 12mo after the surgery.RESULTS:At 3 and 12mo after the surgery,the proportion of simultaneous perception,binocular fusion version and binocular stereo vision in the VPT group was conspicuously higher than that in the control group(P<0.05).After the vision training,the binocular visual perception functions of children in both groups were significantly improved compared with that before training(P<0.05).Interestingly,the grating sharpness,texture perception and texture motion perception in the VPT group were dramatically better than control group(P<0.01).The NCS in the VPT group was significantly lower than that in the control group(P<0.05).The ocular position retraction rate in the VPT group was significantly lower than that in the control group at 12mo(8.89%vs 26.67%,P=0.03).CONCLUSION:VPT effectively promotes binocular visual function reconstruction in intermittent exotropia children after strabismus surgery and reduces the strabismus severity and ocular position retraction rate.
基金supported by the 2021 Myopia Prevention and control Funding in Nan'an District,Chongqing,China(99–2021226).
文摘Objective To compare the perceived eye position,Titmus and stereopsis function across various types of anisometropia to identify differences in binocular visual function.Methods This study included 204 anisometropic patients(observation group,interocular spherical equivalent difference≥1.5D or cylindrical≥1.0D)and 57 non-anisometropic controls(interocular differences<1.5D spherical or<1.0D cylindrical).Participants were initially stratified based on documented amblyopia history(94 with vs.110 without),followed by further subgrouping of the observation group into hyperopic,myopic,and astigmatic anisometropia types for comparative analysis with controls.Standardized assessments comprised best-corrected visual acuity(BCVA,logMAR),cycloplegic refraction,Titmus near stereopsis(arcsec),binocular perceptual eye position(PEP)deviation,and three-order stereopsis thresholds measured via a computerized binocular vision assessment system.Statistical analysis adhered to CONSORT guidelines(SPSS v26.0,α〓〓=〓〓0.05).Results(1)No significant differences were observed between patients with documented amblyopia history and those without regarding equivalent spherical lens difference,horizontal/vertical PEP,three-order stereopsis,or Titmus test results.(2)The control group demonstrated superior vertical PEP,three-order stereopsis,and Titmus performance compared to all anisometropia subgroups(myopic,hypermetropic,and astigmatic;P〓〓<0.05),though horizontal PEP showed no significant variation(P〓〓>0.05).(3)While Titmus results showed no difference between astigmatic and myopic anisometropia groups(P〓〓=〓〓0.72),significant differences existed among other groups(P<0.05).Notably,the hyperopic anisometropia group exhibited the poorest normal rates for vertical PEP,Titmus,and three-order stereopsis among all groups(P〓〓<0.001).Additionally,the astigmatism group outperformed both myopia and hypermetropia groups in 0-order and 1-order stereopsis(P〓〓<0.05).Conclusions The study revealed no significant difference in visual function between anisometropic amblyopia patients who achieved normal BCVA(≤0.0 LogMAR)and non-amblyopic anisometropic controls.However,all forms of anisometropia demonstrated varying degrees of impairment to binocular fusion and stereopsis,with hypermetropic anisometropia showing the most pronounced deficits,particularly in near stereopsis.Notably,vertical PEP instability may contribute to the progression of hyperopic anisometropia.
基金Supported by the Central Guided Local Science and Technology Development (No.2019ZYYD058)。
文摘AIM: To investigate the effects of micro-injection of botulinum toxin A(BTXA) on acute acquired comitant esotropia(AACE). METHODS: A total of 33 AACE patients who underwent BTXA micro-injection at Renmin Hospital of Wuhan University from September 1^(st), 2019 to July 1^(st), 2021 were retrospective analyzed. Esotropia, eye alignment, stereopsis, and complications were examined at baseline(except complications), 1wk, 1, 3, and 6mo after injection. RESULTS: The average angle of deviation before injection was(+20.24±6.80)^(Δ) at near and(+24.76±6.43)^(Δ) at distance, while(+5.15±5.85)^(Δ) at near and(+7.30±6.17)^(Δ) at distance 6mo after treatment(P<0.05). Six months after injection, the stereopsis of patients had improved. The number of patients having no stereopsis(>800 seconds of arc) decreased from 11 to 3. The number of patients having peripheral stereopsis(300-800 seconds of arc), macular stereopsis(70-200 seconds of arc) and central concave stereopsis(≤60 seconds of arc) increased from 10 to 11, 10 to 12, and 2 to 7, respectively. At the follow-ups at 1wk, 1, 3, and 6mo after injection, success rates were 96.97%, 96.97%, 93.94% and 87.88%, respectively. One week after injection, two patients(6.07%) showed subconjunctival hemorrhage;three patients(9.09%) showed limited eye movement and one patient(3.03%) showed mild vertical strabismus. All the symptoms disappeared by the final follow-up.CONCLUSION: Micro-injection of BTXA can reduce diplopia and improve binocular vision function of AACE patients. Furthermore, the operation is relatively safe with few complications, making it an ideal treatment modality for AACE.
