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Potential Applications of Milk Fractions and Valorization of Dairy By-Products: A Review of the State-of-the-Art Available Data, Outlining the Innovation Potential from a Bigger Data Standpoint 被引量:3
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作者 Serge Rebouillat Salvadora Ortega-Requena 《Journal of Biomaterials and Nanobiotechnology》 2015年第3期176-203,共28页
The unique composition of milk makes this basic foodstuff into an exceptional raw material for the production of new ingredients with desired properties and diverse applications in the food industry. The fractionation... The unique composition of milk makes this basic foodstuff into an exceptional raw material for the production of new ingredients with desired properties and diverse applications in the food industry. The fractionation of milk is the key in the development of those ingredients and products;hence continuous research and development on this field, especially various levels of fractionation and separation by filtration, have been carried out. This review focuses on the production of milk fractions as well as their particular properties, applications and processes that increase their exploitation. Whey proteins and caseins from the protein fraction are excellent emulsifiers and protein supplements. Besides, they can be chemically or enzymatically modified to obtain bioactive peptides with numerous functional and nutritional properties. In this context, valorization techniques of cheese-whey proteins, by-product of dairy industry that constitutes both economic and environmental problems, are being developed. Phospholipids from the milk fat fraction are powerful emulsifiers and also have exclusive nutraceutical properties. In addition, enzyme modification of milk phospholipids makes it possible to tailor emulsifiers with particular properties. However, several aspects remain to be overcome;those refer to a deeper understanding of the healthy, functional and nutritional properties of these new ingredients that might be barriers for its use and acceptability. Additionally, in this review, alternative applications of milk constituents in the non-food area such as in the manufacture of plastic materials and textile fibers are also introduced. The unmet needs, the cross-fertilization in between various protein domains,the carbon footprint requirements, the environmental necessities, the health and wellness new demand, etc., are dominant factors in the search for innovation approaches;these factors are also outlining the further innovation potential deriving from those “apparent” constrains obliging science and technology to take them into account. 展开更多
关键词 MILK Product MILK Fractionation CASEIN Phospholipid Whey Protein NON-FOOD Application VALORIZATION Enzyme Modification Bioactive Peptides bigger DATA Innovation: Closed Open Collaborative Disruptive Inclusive Nested
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Recent Strategies for the Development of Biosourced-Monomers, Oligomers and Polymers-Based Materials: A Review with an Innovation and a Bigger Data Focus 被引量:3
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作者 Serge Rebouillat Fernand Pla 《Journal of Biomaterials and Nanobiotechnology》 2016年第4期167-213,共47页
After setting the ground of the quantum innovation potential of biosourced entities and outlining the inventive spectrum of adjacent technologies that can derive from those, the current review highlights, with the sup... After setting the ground of the quantum innovation potential of biosourced entities and outlining the inventive spectrum of adjacent technologies that can derive from those, the current review highlights, with the support of Bigger Data approaches, and a fairly large number of articles, more than 250 and 10,000 patents, the following. It covers an overview of biosourced chemicals and materials, mainly biomonomers, biooligomers and biopolymers;these are produced today in a way that allows reducing the fossil resources depletion and dependency, and obtaining environmentally-friendlier goods in a leaner energy consuming society. A process with a realistic productivity is underlined thanks to the implementation of recent and specifically effective processes where engineered microorganisms are capable to convert natural non-fossil goods, at industrial scale, into fuels and useful high-value chemicals in good yield. Those processes, further detailed, integrate: metabolic engineering involving 1) system biology, 2) synthetic biology and 3) evolutionary engineering. They enable acceptable production yield and productivity, meet the targeted chemical profiles, minimize the consumption of inputs, reduce the production of by-products and further diminish the overall operation costs. As generally admitted the properties of most natural occurring biopolymers (e.g., starch, poly (lactic acid), PHAs.) are often inferior to those of the polymers derived from petroleum;blends and composites, exhibiting improved properties, are now successfully produced. Specific attention is paid to these aspects. Then further evidence is provided to support the important potential and role of products deriving from the biomass in general. The need to enter into the era of Bigger Data, to grow and increase the awareness and multidimensional role and opportunity of biosourcing serves as a conclusion and future prospects. Although providing a large reference database, this review is largely initiatory, therefore not mimicking previous classic reviews but putting them in a multiplying synergistic prospective. 展开更多
关键词 Biomass Biosourced Monomers Advanced Biomaterials Chemical Building Blocks Design Strategy Metabolic Engineering INNOVATION bigger Data
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Paving the High-Way to Sustainable, Value Adding Open-Innovation Integrating Bigger-Data Challenges: Three Examples from Bio-Ingredients to Robust Durable Applications of Electrochemical Impacts 被引量:1
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作者 Salvadora Ortega-Requena Serge Rebouillat Fernand Pla 《Journal of Biomaterials and Nanobiotechnology》 2018年第2期117-188,共72页
A trilogy review, based on more than 300 references, is used to underline three challenges facing 1) the supply of sustainable, durable and protected biosourced ingredients such as lipids, 2) the accounting for valuab... A trilogy review, based on more than 300 references, is used to underline three challenges facing 1) the supply of sustainable, durable and protected biosourced ingredients such as lipids, 2) the accounting for valuable bio-by-products, such as whey proteins that have added-value potential removing their environmental weight and 3) the practical reliable synthetic biology and evolutionary engineering that already serve as a technology and science basis to expand from, such as for biopolymer growth. Bioresources, which are the major topic of this review, must provide answers to several major challenges related to health, food, energy or chemistry of tomorrow. They offer a wide range of ingredients which are available in trees, plants, grasses, vegetables, algae, milk, food wastes, animal manures and other organic wastes. Researches in this domain must be oriented towards a bio-sustainable-economy based on new valuations of the potential of those renewable biological resources. This will aim at the substitution of fossil raw materials with renewable raw materials to ensure the sustainability of industrial processes by providing bioproducts through innovative processes using for instance micro-organisms and enzymes (the so-called white biotechnology). The final stage objective is to manufacture high value-added products gifted with the right set of physical, chemical and biological properties leading to particularly innovative applications. In this review, three examples are considered in a green context open innovation and bigger data environment. Two of them (lipids antioxidants and milk proteins) concern food industry while the third (biomonomers and corresponding bioplastics and derivatives) relates to biomaterials industry. Lipids play a crucial role in the food industry, but they are chemically unstable and very sensitive to atmospheric oxidation which leads to the formation of numerous by-compounds which have adverse effects on lipids quality attributes and on the nutritive value of meat. To overcome this problem, natural antioxidants, with a positive impact on the safety and acceptability of the food system, have been discovered and evaluated. In the same context, milk proteins and their derivatives are of great interest. They can be modified by enzymatic means leading to the formation of by-products that are able to increase their functionality and possible applications. They can also produce bioactive peptides, a field with almost unlimited research potential. On the other hand, biosourced chemicals and materials, mainly biomonomers and biopolymers, are already produced today. Metabolic engineering tools and strategies to engineer synthetic enzyme pathways are developed to manufacture, from renewable feedstocks, with high yields, a number of monomer building-block chemicals that can be used to produce replacements to many conventional plastic materials. Through those three examples this review aims to highlight recent and important advancements in production, modification and applications of the studied bioproducts. Bigger data analysis and artificial intelligence may help reweight practical and theoretical observations and concepts in these fields;helping to cross the boarders of expert traditional exploration fields and sometime fortresses. 展开更多
关键词 BIO Green Sustainability bigger DATA Biomimetic Artificial Intelligence Synthetic Biology Lipids Oxidation Antioxidants Milk Protein WHEY Biopolymers ELECTROCHEMICAL Conductive
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A Review: On Smart Materials Based on Some Polysaccharides;within the Contextual Bigger Data, Insiders, “Improvisation” and Said Artificial Intelligence Trends 被引量:1
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作者 Serge Rebouillat Fernand Pla 《Journal of Biomaterials and Nanobiotechnology》 2019年第2期41-77,共37页
Smart Materials are along with Innovation attributes and Artificial Intelligence among the most used “buzz” words in all media. Central to their practical occurrence, many talents are to be gathered within new conte... Smart Materials are along with Innovation attributes and Artificial Intelligence among the most used “buzz” words in all media. Central to their practical occurrence, many talents are to be gathered within new contextual data influxes. Has this, in the last 20 years, changed some of the essential fundamental dimensions and the required skills of the actors such as providers, users, insiders, etc.? This is a preliminary focus and prelude of this review. As an example, polysaccharide materials are the most abundant macromolecules present as an integral part of the natural system of our planet. They are renewable, biodegradable, carbon neutral with low environmental, health and safety risks and serve as structural materials in the cell walls of plants. Most of them are used, for many years, as engineering materials in many important industrial processes, such as pulp and papermaking and manufacture of synthetic textile fibres. They are also used in other domains such as conversion into biofuels and, more recently, in the design of processes using polysaccharide nanoparticles. The main properties of polysaccharides (e.g. low density, thermal stability, chemical resistance, high mechanical strength…), together with their biocompatibility, biodegradability, functionality, durability and uniformity, allow their use for manufacturing smart materials such as blends and composites, electroactive polymers and hydrogels which can be obtained 1) through direct utilization and/or 2) after chemical or physical modifications of the polysaccharides. This paper reviews recent works developed on polysaccharides, mainly on cellulose, hemicelluloses, chitin, chitosans, alginates, and their by-products (blends and composites), with the objectives of manufacturing smart materials. It is worth noting that, today, the fundamental understanding of the molecular level interactions that confer smartness to polysaccharides remains poor and one can predict that new experimental and theoretical tools will emerge to develop the necessary understanding of the structure-property-function relationships that will enable polysaccharide-smartness to be better understood and controlled, giving rise to the development of new and innovative applications such as nanotechnology, foods, cosmetics and medicine (e.g. controlled drug release and regenerative medicine) and so, opening up major commercial markets in the context of green chemistry. 展开更多
关键词 POLYSACCHARIDES Cellulose Hemicelluloses Chitosan Alginate Composites Blends Hydrogels Smart Materials Electro-Active Papers Sensors Actuators bigger DATA Innovation Science in Education Jazz 4C CRAC
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Bigger Strides in Shandong's Foreign Trade
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作者 Yuan Zhenjiang 《China's Foreign Trade》 1994年第6期32-33,共2页
The year 1994 will see the promotion of further economic restructuring in China and key breakthroughs. The reform of the foreign exchange system, in particular, has provided a rare opportunity for exports in foreign t... The year 1994 will see the promotion of further economic restructuring in China and key breakthroughs. The reform of the foreign exchange system, in particular, has provided a rare opportunity for exports in foreign trade. Facing this favourable situation, the Shandong provincial government has decided export earnings are its main priority and wants to see a 16 to 20 percent growth above the US$5.7 billion earned last year. It will speed up the linking 展开更多
关键词 HIGH bigger Strides in Shandong’s Foreign Trade
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尺寸、显卡升级 联想小新Bigger版
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作者 马汉 《计算机与网络》 2014年第20期26-27,共2页
联想小新2代推出之后,获得了不错的反响。不过14英寸笔记本虽然便携性出色,在散热和游戏性能上相较15英寸产品仍有不少差距。考虑到用户的需求,联想趁热打铁推出了小新产品线的15寸电脑——小新Bigger版。想要屏幕全高清、防眩光,想玩... 联想小新2代推出之后,获得了不错的反响。不过14英寸笔记本虽然便携性出色,在散热和游戏性能上相较15英寸产品仍有不少差距。考虑到用户的需求,联想趁热打铁推出了小新产品线的15寸电脑——小新Bigger版。想要屏幕全高清、防眩光,想玩游戏不卡顿、上网超流畅,想看电影听音乐获得家庭影院级别。这样的需求集成在一款笔记本上无论怎么想也是价值不菲,很多用户可能只是想想而已。 展开更多
关键词 bigger 游戏性能 家庭影院 眩光 触控板 抗锯齿 大型游戏 影音娱乐 腾讯 续航时间
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A Bigger Role in World Trade
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作者 Chen Youjun an assistant research fellow with the Shanghai Institutes for International Studies 《ChinAfrica》 2011年第12期32-33,共2页
China helps make global trade fairer and more beneficial to less developed countries WITH the rise of emerging countries represented by China and some other countries,the current international trade system is embracin... China helps make global trade fairer and more beneficial to less developed countries WITH the rise of emerging countries represented by China and some other countries,the current international trade system is embracing a reform. A prominent feature of this reform is the participation of an increasing number of countries and regions. 展开更多
关键词 World A bigger Role in World Trade WTO
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The Bigger Enemy from Inside
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《ChinAfrica》 2012年第6期35-35,共1页
THE year 2010 embraced the world's new manufacturing king, China, who regained the top manufacturer position after the United States had occupied it for more than 100 years since 1895. In 2010, China accounted for 19... THE year 2010 embraced the world's new manufacturing king, China, who regained the top manufacturer position after the United States had occupied it for more than 100 years since 1895. In 2010, China accounted for 19.8 percent of world manufacturing output, fractionally ahead of the United States with 19.4 percent. However, since China reversed to the top position, its manufacturing sector has been facing challenges and pressures. 展开更多
关键词 In The bigger Enemy from Inside
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Bigger for Better
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作者 Hou Weili Yu Lintao 《ChinAfrica》 2017年第10期38-39,共2页
KIMENG Hilton Ndukong, a journalist from the Cameroon Tribune. envisions a future where more African countries will further align with other developing nations through investment and shared practices.
关键词 bigger for Better
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“Being Stronger,Better and Bigger”:The Logical Unity of Theory and Practice of State-owned Enterprise Reform-Development Course and Prospect of State-owned Enterprises in China
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作者 DING Xiaoqin 《Frontiers of Business Research in China》 2023年第1期2-26,共25页
China’s state-owned enterprises(SOEs)have developed more than 70 years since the People’s Republic of China(PRC)was founded in 1949.From 1949 to 1978,SOEs provided material guarantee for the construction of the PRC,... China’s state-owned enterprises(SOEs)have developed more than 70 years since the People’s Republic of China(PRC)was founded in 1949.From 1949 to 1978,SOEs provided material guarantee for the construction of the PRC,laid a solid foundation for the industrialization process,and ensured that the people were masters of their own affairs.From 1978 to 2012,SOEs upgraded their growth quality and increased their efficiency for improving people’s material and cultural life.Since 2012,SOEs have become“stronger,better and bigger”on all fronts for satisfying people’s growing expectations for a better life.In essence,reforming SOEs means interpreting and exercising the people-centered development philosophy,and means addressing principal social contradiction through different stages of socialist development,as SOEs care about the main needs of the people.Such a development is a process of constant exploration and continuous growth from strength to strength,which is the inherent logic of theory and practice of SOE growth in new China for more than 70 years. 展开更多
关键词 state-owned enterprises be stronger better and bigger people-centered principal social contradiction
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SMARTER, BIGGER, STRONGER
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作者 Wang Jun 《Beijing Review》 2019年第39期14-15,共2页
List of China’s top 500 companies shows new trends Profitability,innovation and internationalization—these are some of the focuses of the country’s top companies.Seventy years after the founding of the People’s Re... List of China’s top 500 companies shows new trends Profitability,innovation and internationalization—these are some of the focuses of the country’s top companies.Seventy years after the founding of the People’s Republic of China in 1949,China’s corporate scene has transformed,with market forces playing a dominant role. 展开更多
关键词 bigger SMARTER STRONGER China
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Bigger Voice,Bigger Responsibility
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作者 HU YUE 《Beijing Review》 2010年第18期32-33,共2页
China gains clout in the World Bank following voting reform The World Bank granted greater voting power to China and other developing countries, marking a significant milestone in its structural reform. At the joint D... China gains clout in the World Bank following voting reform The World Bank granted greater voting power to China and other developing countries, marking a significant milestone in its structural reform. At the joint Development Committee meeting of the World Bank 展开更多
关键词 World bigger Voice bigger Responsibility IMF
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Better Economy Provides Bigger Space for Reform
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作者 Zhang Deyong 《Beijing Review》 2017年第39期36-36,共1页
Figures from the National Bureau of Statistics reveal that the Chinese economy performed in a stable manner and had good momentum for growth in August.In the month,the output of industrial enterprises above the design... Figures from the National Bureau of Statistics reveal that the Chinese economy performed in a stable manner and had good momentum for growth in August.In the month,the output of industrial enterprises above the designated size——an annual revenue from their main business operations of 20 million yuan($3.04 million)——grew 6percent in real terms. 展开更多
关键词 In Better Economy Provides bigger Space for Reform CPI
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Small Potatoes Growing Bigger
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作者 FENG JIANHUA 《Beijing Review》 2008年第14期20-21,共2页
The social and economic status of rural migrant laborers is improving steadily Rural migrant work- crs arc the offspring of China’s transition from an agricultural to industrial society.The year 2008 marks the 30th a... The social and economic status of rural migrant laborers is improving steadily Rural migrant work- crs arc the offspring of China’s transition from an agricultural to industrial society.The year 2008 marks the 30th anni- versary of China’s reform and opening-up policy.In the past three decades,dramatic social and economic changes have taken place.As a spe- cial social group,what have rural workers contributed to the social and economic development of China? Wang Chunguang,a research fel- low studying rural migrant workers in the Institute of Sociology at the 展开更多
关键词 In Small Potatoes Growing bigger
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Gaining a Bigger Say
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作者 DING YING 《Beijing Review》 2010年第44期10-11,共2页
The recent hike in China’s IMF quota means its international voice will increase Finance ministers and central bank governors from the Group of 20(G20) major economies agreed on October 23 to shift more than 6 percen... The recent hike in China’s IMF quota means its international voice will increase Finance ministers and central bank governors from the Group of 20(G20) major economies agreed on October 23 to shift more than 6 percent of 展开更多
关键词 IMF Gaining a bigger Say
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GROWING PAINS OR GROWING GAINS? Chinese automakers are definitely getting bigger internationally,but they still need to get better
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作者 LIU YUNYUN 《Beijing Review》 2006年第51期32-34,共3页
关键词 Chinese automakers are definitely getting bigger internationally but they still need to get better GROWING PAINS OR GROWING GAINS WTO
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A Bigger Stage
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作者 FENG JIANHUA 《Beijing Review》 2009年第10期18-19,共2页
After being away from his home country for 18 years, a financial expert backs to Beijing to pursue his dream
关键词 A bigger Stage
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A Bigger Political Gamble
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作者 TIAN WENLIN a researcher with the Institute of Asian and African Studies, China Institutes of Contemporary International Relations 《Beijing Review》 2007年第5期14-14,共1页
The tough U.S. stance on Iran could trigger another round of games that is more perilous than the one it played in Iraq The United States has taken a number of steps against Iran recently, arresting and detaining five... The tough U.S. stance on Iran could trigger another round of games that is more perilous than the one it played in Iraq The United States has taken a number of steps against Iran recently, arresting and detaining five Iranian consular staffers in Erbil, north Iraq,freezing all the assets of Bank Sepah within the United States and sending a second aircraft carrier to the Gulf region.News reports predicting a U.S. military strike on Iran have run wild, with some Arabic media speculating that Washington has decided to launch an attack from the sea before April. 展开更多
关键词 A bigger Political Gamble
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A Bigger Role to Play
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作者 LI LI 《Beijing Review》 2011年第9期16-17,共2页
Trade unions face heavy tasks of better representing and safeguarding employee interests According to Chinese tradition, all debts should be paid before the New Year. However, two recent cases
关键词 A bigger Role to Play
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Sometimes I think that I’m bigger than the sound
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作者 朴九月 《音乐大观》 2007年第11期4-7,共4页
  当网络几乎已经成为我等这般宅男宅女交流沟通的唯一媒介,当寝室教室办公室几乎已经成为我等这般平凡世人蜗居浅出的少数场所,当书本碟片几乎已经成为我等这般干物女汲取营养的几种商品,各种户外音乐节的频密出现,不知道到底意味着...   当网络几乎已经成为我等这般宅男宅女交流沟通的唯一媒介,当寝室教室办公室几乎已经成为我等这般平凡世人蜗居浅出的少数场所,当书本碟片几乎已经成为我等这般干物女汲取营养的几种商品,各种户外音乐节的频密出现,不知道到底意味着什么………… 展开更多
关键词 摩登天空 Sometimes I think that I’m bigger than the sound 音乐节 主舞台 摇滚乐 守望者 林一峰
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