Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo...Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.展开更多
AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions fo...AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions for future studies.METHODS:A systematic search was conducted in the Web of Science Core Collection(WoSCC)database to retrieve relevant literature published from January 1,2000,to August 31,2025(data accessed on September 12,2025).Multiple data visualization tools were employed to conduct in-depth analyses of the included publications,covering aspects such as publication quantity and quality,evolutionary trends of research hotspots,keyword cooccurrence networks,and collaborative patterns among countries/regions,institutions,and authors.RESULTS:A total of 3381 articles related to glaucoma inflammation were extracted from WoSCC.The analysis showed that the USA had the highest research output in this field(29.04%,n=982),followed by China(18.40%,n=622)and UK(6.01%,n=203).Based on citation frequency and burst intensity,the USA also ranked as the most influential country.Baudouin C and Sun X were identified as the most productive authors,while Journal of Glaucoma and Investigative Ophthalmology&Visual Science were the journals with the highest number of published relevant articles.Additionally,keyword analysis revealed that“neuroinflammation”,“retinal ganglion cells(RGCs)”,“pathophysiology”,and“traditional Chinese medicine”are emerging research hotspots in the field of immuneinflammatory responses in glaucoma.CONCLUSION:This study presents a comprehensive bibliometric overview of research on glaucoma-related inflammation,indicating that this field has received extensive scientific attention with a steady upward trend in research activity.Furthermore,it establishes a theoretical basis for the development of neuroinflammation-targeted therapeutic strategies for glaucoma and emphasizes the necessity of strengthening interdisciplinary collaboration to promote the clinical translation of research findings.展开更多
AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 ...AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.展开更多
AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current resea...AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.展开更多
AIM:To assess the current research status and emerging trends of the choriocapillaris(CC)by bibliometric analysis.METHODS:Publications spanning from January 2013 to May 2023 were retrieved on June 27th,2023,using the ...AIM:To assess the current research status and emerging trends of the choriocapillaris(CC)by bibliometric analysis.METHODS:Publications spanning from January 2013 to May 2023 were retrieved on June 27th,2023,using the Web of Science Core Collection.Bibliometric and visualized analyses were performed employing the bibliometrix,CiteSpace and VOSviewer.RESULTS:A total of 1563 papers met the inclusion criteria,and a publication growth trend was observed.The United States was the leading country in the CC field.Retina and Investigative Ophthalmology&Visual Science stood out as highly impactful and prolific journals.Research topics in the CC field encompassed choroidal neovascularization,choroidal thickness,central serous chorioretinopathy,agerelated macular degeneration,myopia,choroidal vascularity index,and diabetic retinopathy,based on the co-citation analysis.The keyword“high myopia”experienced a burst lasting until 2023.CONCLUSION:In the past decade,research in the field of CC has flourished due to recent advancements in choroidal imaging;with focus shifting towards elucidating its role in various diseases.This will provide novel insights into managing chorioretinal diseases and vision-preserving interventions.展开更多
Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric ana...Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric analysis was conducted in accordance with the PRISMA 2020 statement.Peer-reviewed articles published in English from 2015 to 2025 were retrieved from Scopus,Web of Science,and PubMed.Thematic clustering was conducted using the Louvain algorithm and cosine similarity.A subset of 66 frequently cited articles was then qualitatively synthesized to capture core competencies across clusters.Results A total of 83,807 articles were included for bibliometric analysis.Of these,66 articles were chosen for thematic analysis.Five major thematic clusters were identified:remote care in primary settings,oncology and palliative care,nurse education and training,safety and quality in nursing practice,and geriatric and dementia care.Additionally,four competency domains were identified:telehealth and remote communication,health systems and informatics,digital tools in practice,and AI-powered decision support.A clear shift in research focus was observed,with the emphasis transitioning from foundational digital skills before the COVID-19 pandemic to more advanced competencies during the post-pandemic digital transformation,encompassing ethical reasoning,immersive technology use,and AI integration.Conclusions Integrating digital and AI technologies is reshaping nursing practice across various thematic areas and competency domains,highlighting a transition from foundational digital tasks to AI-supported decision-making and ethically informed technology use.This study provides a structured overview of evolving competencies in digital nursing and synthesizes evidence to support future research,curriculum design,and policy planning.展开更多
BACKGROUND In recent years,numerous reports have been published regarding the relationship between the gut microbiota and the tumor immune microenvironment(TIME).However,to date,no systematic study has been conducted ...BACKGROUND In recent years,numerous reports have been published regarding the relationship between the gut microbiota and the tumor immune microenvironment(TIME).However,to date,no systematic study has been conducted on the relationship between gut microbiota and the TIME using bibliometric methods.AIM To describe the current global research status on the correlation between gut microbiota and the TIME,and to identify the most influential countries,research institutions,researchers,and research hotspots related to this topic.METHODS We searched for all literature related to gut microbiota and TIME published from January 1,2014,to May 28,2024,in the Web of Science Core Collection database.We then conducted a bibliometric analysis and created visual maps of the published literature on countries,institutions,authors,keywords,references,etc.,using CiteSpace(6.2R6),VOSviewer(1.6.20),and bibliometrics(based on R 4.3.2).RESULTS In total,491 documents were included,with a rapid increase in the number of publications starting in 2019.The country with the highest number of publications was China,followed by the United States.Germany has the highest number of citations in literature.From a centrality perspective,the United States has the highest influence in this field.The institutions with the highest number of publications were Shanghai Jiao Tong University and Zhejiang University.However,the institution with the most citations was the United States National Cancer Institute.Among authors,Professor Giorgio Trinchieri from the National Institutes of Health has the most local impact in this field.The most cited author was Fan XZ.The results of journal publications showed that the top three journals with the highest number of published papers were Frontiers in Immunology,Cancers,and Frontiers in Oncology.The three most frequently used keywords were gut microbiota,tumor microenvironment,and immunotherapy.CONCLUSION This study systematically elaborates on the research progress related to gut microbiota and TIME over the past decade.Research results indicate that the number of publications has rapidly increased since 2019,with research hotspots including“gut microbiota”,“tumor microenvironment”and“immunotherapy”.Exploring the effects of specific gut microbiota or derived metabolites on the behavior of immune cells in the TIME,regulating the secretion of immune molecules,and influencing immunotherapy are research hotspots and future research directions.展开更多
As the global community strives to achieve the Sustainable Development Goals(SDG),bibliometric analysis offers valuable insights into research trends,impact,and collaboration patterns related to these critical areas.W...As the global community strives to achieve the Sustainable Development Goals(SDG),bibliometric analysis offers valuable insights into research trends,impact,and collaboration patterns related to these critical areas.We are excited to announce a special issue focused on“Fostering SDG-related Research through the Lens of Bibliometrics.”展开更多
AIM:To comprehensively investigate the current state of research on the application of neurotrophic factors in glaucoma therapy and identify potential research hotspots.METHODS:On September 30,2023,a literature search...AIM:To comprehensively investigate the current state of research on the application of neurotrophic factors in glaucoma therapy and identify potential research hotspots.METHODS:On September 30,2023,a literature search was conducted on Scopus using specific keywords related to neurotrophic factors and glaucoma.Of the 918 articles retrieved,780 met the inclusion criteria.These articles were subsequently analyzed and visualized using Google Sheets,Biblioshiny 3.1,and VosViewer 1.6.18.RESULTS:A total of 780 studies published between 1989 and 2023 were included,and the global publication count showed an upward trend through 2023(projected to continue rising by 2030).The United States,China,Japan,Italy,and Australia were the most significant contributors to the publication output.Research in this field had been published in 313 journals,spanning categories such as pharmacology and drug development,ophthalmology,genetics and gene therapy,and neuroscience.A total of 2622 authors had contributed to these studies,with the most prolific author publishing 14 articles.The focus of research in this field had evolved sequentially from“glutamate”to“CNTF”and“GDNF”,and finally to“optic nerve injury”.Co-occurrence analysis identified five clusters:glaucoma and ocular health,neuroinflammation in ophthalmology,neuroprotection in ophthalmology,ocular drug delivery,and stem cell therapy.Several areas in this field require further exploration,including the neurophysiological mechanisms underlying glaucoma,ocular drug delivery systems,and the clinical value of specific neurotrophic factors.CONCLUSION:This study systematically reviews global research trends on neurotrophic factors in glaucoma therapy,clarifying the current research status and future directions.展开更多
BACKGROUND Gastrointestinal endoscopy has been widely used in the diagnosis and treatment of gastrointestinal diseases.A great many of studies on gastrointestinal endoscopy have been done.AIM To analyze the characteri...BACKGROUND Gastrointestinal endoscopy has been widely used in the diagnosis and treatment of gastrointestinal diseases.A great many of studies on gastrointestinal endoscopy have been done.AIM To analyze the characteristics of top 100 cited articles on gastrointestinal endoscopy.METHODS A bibliometric analysis was conducted.The publications and their features were extracted from the Web of Science Core Collection,Science Citation Index-Expanded database.Excel,Web of Science database and SPSS software were used to perform the statistical description and analysis.VOSviewer software and Map-Chart were responsible for the visualizations.RESULTS The top 100 cited articles were published between 1976 and 2022.The guidelines(52%)and clinical trials(37%)are the main article types,and average publication year of the guidelines is much later than that of the clinical trials(2015 vs 1998).Among the clinical trials,diagnostic study(27.0%),cohort study(21.6%),case series(13.5%)and cross-sectional study(10.8%)account for a large proportion.Average citations of different study types and designs of the enrolled studies are of no significant differences.Most of the 100 articles were published by European authors and recorded by the endoscopic journals(65%).Top journals in medicine,such as the Lancet,New England Journal of Medicine and JAMA,also reported studies in this field.The hot spots of involved diseases include neoplasm or cancer-related diseases,inflammatory diseases,obstructive diseases,gastrointestinal hemorrhage and ulcer.Endoscopic surgery,endoscopic therapy and stent placement are frequently studied.CONCLUSION Our research contributes to delineating the field and identifying the characteristics of the most highly cited articles.It is noteworthy that there is a significantly smaller number of clinical trials included compared to guidelines,indicating potential areas for future high-quality clinical trials.展开更多
Accurate estimation of evapotranspiration(ET)is crucial for efficient water resource management,particularly in the face of climate change and increasing water scarcity.This study performs a bibliometric analysis of 3...Accurate estimation of evapotranspiration(ET)is crucial for efficient water resource management,particularly in the face of climate change and increasing water scarcity.This study performs a bibliometric analysis of 352 articles and a systematic review of 35 peer-reviewed papers,selected according to PRISMA guidelines,to evaluate the performance of Hybrid Artificial Neural Networks(HANNs)in ET estimation.The findings demonstrate that HANNs,particularly those combining Multilayer Perceptrons(MLPs),Recurrent Neural Networks(RNNs),and Convolutional Neural Networks(CNNs),are highly effective in capturing the complex nonlinear relationships and tem-poral dependencies characteristic of hydrological processes.These hybrid models,often integrated with optimization algorithms and fuzzy logic frameworks,significantly improve the predictive accuracy and generalization capabilities of ET estimation.The growing adoption of advanced evaluation metrics,such as Kling-Gupta Efficiency(KGE)and Taylor Diagrams,highlights the increasing demand for more robust performance assessments beyond traditional methods.Despite the promising results,challenges remain,particularly regarding model interpretability,computational efficiency,and data scarcity.Future research should prioritize the integration of interpretability techniques,such as attention mechanisms,Local Interpretable Model-Agnostic Explanations(LIME),and feature importance analysis,to enhance model transparency and foster stakeholder trust.Additionally,improving HANN models’scalability and computational efficiency is crucial,especially for large-scale,real-world applications.Approaches such as transfer learning,parallel processing,and hyperparameter optimization will be essential in overcoming these challenges.This study underscores the transformative potential of HANN models for precise ET estimation,particularly in water-scarce and climate-vulnerable regions.By integrating CNNs for automatic feature extraction and leveraging hybrid architectures,HANNs offer considerable advantages for optimizing water management,particularly agriculture.Addressing challenges related to interpretability and scalability will be vital to ensuring the widespread deployment and operational success of HANNs in global water resource management.展开更多
BACKGROUND Hepatic organoid-based modelling,through the elucidation of a range of in vivo biological processes and the recreation of the intricate liver microenvironment,is yielding groundbreaking insights into the pa...BACKGROUND Hepatic organoid-based modelling,through the elucidation of a range of in vivo biological processes and the recreation of the intricate liver microenvironment,is yielding groundbreaking insights into the pathophysiology and personalized medicine approaches for liver diseases.AIM This study was designed to analyse the global scientific output of hepatic organoid research and assess current achievements and future trends through bibliometric analysis.METHODS Articles were retrieved from the Web of Science Core Collection,and CiteSpace 6.3.R1 was employed to analyse the literature,including outputs,journals,and countries,among others.RESULTS Between 2010 and 2024,a total of 991 articles pertaining to hepatic organoid research were published.The journal Hepatology published the greatest number of papers,and journals with an impact factor greater than 10 constituted 60%of the top 10 journals.The United States and Utrecht University were identified as the most prolific country and institution,respectively.Clevers H emerged as the most prolific author,whereas Huch M had the highest number of cocitations,suggesting that both are ideal candidates for academic collaboration.Research on hepatic organoids has exhibited a progressive shift in focus,evolving from initial investigations into model building,differentiation research in stem cells,bile ducts,and progenitor cells,to a broader spectrum encompassing lipid metabolism,single-cell RNA sequencing,and therapeutic applications.The phrases exhibiting citation bursts from 2022 to 2024 include“drug resistance”,“disease model”,and“patient-derived tumor organoids”.CONCLUSION Research on hepatic organoids has increased over the past decade and is expected to continue to grow.Key research areas include applications for liver diseases and drug development.Future trends likely to gain focus include patient-derived tumour organoids,disease modelling,and personalized medicine.展开更多
Methane contributes to global warming,and livestock is one of the sources of methane production.However,methane emission studies using bibliometric tools in livestock are lacking.Given the negative impact of climate c...Methane contributes to global warming,and livestock is one of the sources of methane production.However,methane emission studies using bibliometric tools in livestock are lacking.Given the negative impact of climate change on the ecosystem and the rise in methane emissions,it is essential to conduct a bibliometrics study to provide an overview and research trends.We used the Bibliometrix package and VOSviewer to decipher bibliometric indices for methane emissions in cattle farms(MECF).Current dataset were collected from the Web of Science(Core Collection)database,and 8,998 publications were analyzed.The most co-occurring keywords scientists preferred were methane(1,528),greenhouse gas(443),methane emissions(440),and cattle(369).Methane was the most frequently used keyword in the published scientific literature.Thematic evolution of research themes and trend results highlighted carbon dioxide,methane,dairy cattle,cattle,and risk factors during 1999–2017.Chinese Academy of Sciences ranked on top with 485 publications,followed by Agriculture&Agri-Food Canada,University of Colorado,National Oceanic and Atmospheric Administration,and Aarhus University.Chinese Academy of Sciences was also the most cited organization,followed by the University of Colorado,Agriculture&Agri-Food Canada,National Oceanic and Atmospheric Administration,and United States Geological Survey.Source analysis showed that the Science of the Total Environment was cited with the highest total link strength.Science of the Total Environment ranked first in source core 1 with 290 citation frequencies,followed by Journal of Dairy Science with 223 citation frequencies.Currently,no bibliometric study has been conducted on MECF,and to fill this knowledge gap,we carried out this study to highlight methane emissions in cattle farms,aiming at a climate change perspective.In this regard,we focused on the research productivity of countries authors,journals and institutions,co-occurrence of keywords,evolution of research trends,and collaborative networking.Based on relevance degree of centrality,methane emissions and greenhouse gases appeared as basic themes,cattle,and dairy cattle appeared as emerging/declining themes,whereas,methane,greenhouse gas and nitrous oxide appeared to fall amongst basic and motor themes.On the other hand,beef cattle,rumen and dairy cow seem to be between motor and niche themes,and risk factors lie in niche themes.The present bibliometric analysis provides research progress on methane emissions in cattle farms.Current findings may provide a framework for understanding research trends and themes in MECF research.展开更多
Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advan...Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advancements in IM,comprehensive bibliometric reviews remain limited.This article systematically reviews the latest research in IM,addressing emerging hotspots,key technologies,and their applications across the entire product manufacturing cycle.Bibliometric analysis is employed to identify research trends visualize publication volume,collaboration patterns,research domains,co-citations,and emerging areas of interest.The article then examines key technologies supporting IM,including sensors,the Internet of Things(IoT),big data analytics,cloud computing,artificial intelligence(AI),digital twins,and virtual reality(VR)/augmented reality(AR).Furthermore,it explores the application of these technologies throughout the manufacturing cycle-from intelligent reliability design,material transportation and tracking,to intelligent planning and scheduling,machining and fabrication,monitoring and maintenance,quality inspection and control,warehousing and management,and sustainable green manufacturing—through specific case studies.Lastly,the article discusses future research directions,highlighting the increasing global market and the need for enhanced interdisciplinary collaboration,technological integration,computing power upgrades,and attention to security and privacy in IM.This study provides valuable insights for scholars and serves as a guide for future research and strategic investment decisions,offering a comprehensive view of the IM field.展开更多
BACKGROUND Diabetes has a substantial impact on public health,highlighting the need for novel treatments.Ubiquitination,an intracellular protein modification process,is emerging as a promising strategy for regulating ...BACKGROUND Diabetes has a substantial impact on public health,highlighting the need for novel treatments.Ubiquitination,an intracellular protein modification process,is emerging as a promising strategy for regulating pathological mechanisms.We hypothesize that ubiquitination plays a critical role in the development and progression of diabetes and its complications,and that understanding these mechanisms can lead to new therapeutic approaches.AIM To uncover the research trends and advances in diabetes ubiquitination and its complications,we conducted a bibliometric analysis.METHODS Studies on ubiquitination in diabetes mellitus and its complications were retrieved from the Web of Science Core Collection.Visual mapping analysis was conducted using the CiteSpace software.RESULTS We gathered 791 articles published over the past 23 years,focusing on ubiquitination in diabetes and its associated complications.These articles originated from 54 countries and 386 institutions,with China as the leading contributor.Shanghai Jiao Tong University has the highest number of publications in this field.The most prominent authors contributing to this research area include Wei-Hua Zhang,with Zhang Y being the most frequently cited author.Additionally,The Journal of Biological Chemistry is noted as the most cited in this field.The predominant keywords included expression,activation,oxidative stress,phosphorylation,ubiquitination,degradation,and insulin resistance.CONCLUSION The role of ubiquitination in diabetes and its complications,such as diabetic nephropathy and cardiomyopathy,is a key research focus.However,these areas require further investigations.展开更多
BACKGROUND Diabetic foot ulcers(DFUs)are a significant contributor to disability and mortality in diabetic patients.Macrophage polarization and functional regulation are promising areas of research and show therapeuti...BACKGROUND Diabetic foot ulcers(DFUs)are a significant contributor to disability and mortality in diabetic patients.Macrophage polarization and functional regulation are promising areas of research and show therapeutic potential in the field of DFU healing.However,the complex mechanism,the difficulty in clinical translation,and the large heterogeneity present significant challenges.Hence,this study was to comprehensively analyze the publication status and trends of studies on macrophage polarization and DFU healing.AIM To examine the relevant literature on macrophage polarization in DFU healing.METHODS A bibliometric analysis was conducted using the Web of Science database.Relevant literature was retrieved from the Web of Science Core Collection database between 2013 to 2023 using literature visualization and analysis software(VOSviewer and CiteSpace)and bibliometric online platforms.The obtained literature was then subjected to visualization and analysis of different countries/regions,institutions,journals,authors,and keywords to reveal the research’s major trends and focus.RESULTS The number of publications on the role of macrophage polarization in DFU healing increased rapidly from 2013 to 2023,especially in the latter period.Chinese researchers were the most prolific in this field,with 217 publications,while American researchers had been engaged in this field for a longer period.Qian Tan of Nanjing Drum Tower Hospital and Qian Ding of Nanjing University were the first to publish in this field.Shanghai Jiao Tong University was the institution with the most publications(27).The keywords“bone marrow”,“adjustment,replacement,response,tissue repair”,and“activation,repair,differentiation”appeared more frequently.The study of macrophage polarization in DFU healing focused on the regulatory mechanism,gene expression,and other aspects.CONCLUSION This study through the bibliometric method reveals the research trends and development trends in this field of macrophage polarization in DFU healing from 2013 to 2023 in the Web of Science Core Collection database.The key hotspots in this field mainly include the regulation of macrophage activation,gene expression,wound tissue repair,and new wound materials.This study provides references for future research directions.展开更多
BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of...BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of global research on BD drug treatment over the last decade.METHODS The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were extracted.Data visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks.The University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this field.The Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.CONCLUSION This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future directions.The study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.展开更多
BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is lacking.AIM To conduct a bibliometric analysis to investigate the current status and fronti...BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is lacking.AIM To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.METHODS The documents related to SSD are obtained from the web of science core collection database(WoSCC),and VOSviewer 1.6.16 from January 1,2000 to December 31,2023,and the WoSCC’s literature analysis wire were used to conduct the biblio-metric analysis.RESULTS A total of 567 documents related to SSD were included,and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research,published in 277 journals.The most productive author,institution,country and journal were Löwe B,University of Hamburg,Germany,and Journal of Psycho-somatic Research respectively.The first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues,which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.CONCLUSION In conclusion,the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria,functional impairment of SSD,and the treatment for SSD.More high-quality studies are needed to assess the diagnosis and treatment of SSD.展开更多
BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications...BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.展开更多
In this editorial,we comment on the recent article by Fei et al exploring the field of near-infrared spectroscopy(NIRS)research in schizophrenia from a bibliometrics perspective.In recent years,NIRS has shown unique a...In this editorial,we comment on the recent article by Fei et al exploring the field of near-infrared spectroscopy(NIRS)research in schizophrenia from a bibliometrics perspective.In recent years,NIRS has shown unique advantages in the auxiliary diagnosis of schizophrenia,and the introduction of bibliometrics has provided a macro perspective for research in this field.Despite the opportunities brought about by these technological developments,remaining challenges require multidi-sciplinary approach to devise a reliable and accurate diagnosis system for schizo-phrenia.Nonetheless,NIRS-assisted technology is expected to contribute to the division of methods for early intervention and treatment of schizophrenia.展开更多
文摘Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.
基金Supported by the National Natural Science Foundation of China(No.82074500)Beijing Natural Science Foundation(No.7252273)+2 种基金CACMS Innovation Fund(No.CI2021A02605)Administration of Traditional Chinese Medicine of Zhejiang Province(No.2024ZR029)Science and Technology Program of Wenzhou City(No.Y2023210).
文摘AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions for future studies.METHODS:A systematic search was conducted in the Web of Science Core Collection(WoSCC)database to retrieve relevant literature published from January 1,2000,to August 31,2025(data accessed on September 12,2025).Multiple data visualization tools were employed to conduct in-depth analyses of the included publications,covering aspects such as publication quantity and quality,evolutionary trends of research hotspots,keyword cooccurrence networks,and collaborative patterns among countries/regions,institutions,and authors.RESULTS:A total of 3381 articles related to glaucoma inflammation were extracted from WoSCC.The analysis showed that the USA had the highest research output in this field(29.04%,n=982),followed by China(18.40%,n=622)and UK(6.01%,n=203).Based on citation frequency and burst intensity,the USA also ranked as the most influential country.Baudouin C and Sun X were identified as the most productive authors,while Journal of Glaucoma and Investigative Ophthalmology&Visual Science were the journals with the highest number of published relevant articles.Additionally,keyword analysis revealed that“neuroinflammation”,“retinal ganglion cells(RGCs)”,“pathophysiology”,and“traditional Chinese medicine”are emerging research hotspots in the field of immuneinflammatory responses in glaucoma.CONCLUSION:This study presents a comprehensive bibliometric overview of research on glaucoma-related inflammation,indicating that this field has received extensive scientific attention with a steady upward trend in research activity.Furthermore,it establishes a theoretical basis for the development of neuroinflammation-targeted therapeutic strategies for glaucoma and emphasizes the necessity of strengthening interdisciplinary collaboration to promote the clinical translation of research findings.
基金Supported by National Natural Science Foundation of China(No.82020108006,No.81730025).
文摘AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.
基金Suppotred by Tianjin Key Medical Discipline Construction Project(No.TJYXZDXK-3-004A-2).
文摘AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.
文摘AIM:To assess the current research status and emerging trends of the choriocapillaris(CC)by bibliometric analysis.METHODS:Publications spanning from January 2013 to May 2023 were retrieved on June 27th,2023,using the Web of Science Core Collection.Bibliometric and visualized analyses were performed employing the bibliometrix,CiteSpace and VOSviewer.RESULTS:A total of 1563 papers met the inclusion criteria,and a publication growth trend was observed.The United States was the leading country in the CC field.Retina and Investigative Ophthalmology&Visual Science stood out as highly impactful and prolific journals.Research topics in the CC field encompassed choroidal neovascularization,choroidal thickness,central serous chorioretinopathy,agerelated macular degeneration,myopia,choroidal vascularity index,and diabetic retinopathy,based on the co-citation analysis.The keyword“high myopia”experienced a burst lasting until 2023.CONCLUSION:In the past decade,research in the field of CC has flourished due to recent advancements in choroidal imaging;with focus shifting towards elucidating its role in various diseases.This will provide novel insights into managing chorioretinal diseases and vision-preserving interventions.
基金supported by grants for development of new faculty staff,Ratchadaphiseksomphot Fund,Chulalongkorn University,Thailand.
文摘Objectives This study aimed to explore the research trends,thematic structures,and core competency domains in the field of nursing-related digital and artificial intelligence(AI)technologies.Methods A bibliometric analysis was conducted in accordance with the PRISMA 2020 statement.Peer-reviewed articles published in English from 2015 to 2025 were retrieved from Scopus,Web of Science,and PubMed.Thematic clustering was conducted using the Louvain algorithm and cosine similarity.A subset of 66 frequently cited articles was then qualitatively synthesized to capture core competencies across clusters.Results A total of 83,807 articles were included for bibliometric analysis.Of these,66 articles were chosen for thematic analysis.Five major thematic clusters were identified:remote care in primary settings,oncology and palliative care,nurse education and training,safety and quality in nursing practice,and geriatric and dementia care.Additionally,four competency domains were identified:telehealth and remote communication,health systems and informatics,digital tools in practice,and AI-powered decision support.A clear shift in research focus was observed,with the emphasis transitioning from foundational digital skills before the COVID-19 pandemic to more advanced competencies during the post-pandemic digital transformation,encompassing ethical reasoning,immersive technology use,and AI integration.Conclusions Integrating digital and AI technologies is reshaping nursing practice across various thematic areas and competency domains,highlighting a transition from foundational digital tasks to AI-supported decision-making and ethically informed technology use.This study provides a structured overview of evolving competencies in digital nursing and synthesizes evidence to support future research,curriculum design,and policy planning.
基金Supported by the Shanghai Science and Technology Commission Project,No.21010504300Shanghai Jiading District Traditional Chinese Medicine Key Specialty Construction Project,No.2020-JDZYYZDZK-01.
文摘BACKGROUND In recent years,numerous reports have been published regarding the relationship between the gut microbiota and the tumor immune microenvironment(TIME).However,to date,no systematic study has been conducted on the relationship between gut microbiota and the TIME using bibliometric methods.AIM To describe the current global research status on the correlation between gut microbiota and the TIME,and to identify the most influential countries,research institutions,researchers,and research hotspots related to this topic.METHODS We searched for all literature related to gut microbiota and TIME published from January 1,2014,to May 28,2024,in the Web of Science Core Collection database.We then conducted a bibliometric analysis and created visual maps of the published literature on countries,institutions,authors,keywords,references,etc.,using CiteSpace(6.2R6),VOSviewer(1.6.20),and bibliometrics(based on R 4.3.2).RESULTS In total,491 documents were included,with a rapid increase in the number of publications starting in 2019.The country with the highest number of publications was China,followed by the United States.Germany has the highest number of citations in literature.From a centrality perspective,the United States has the highest influence in this field.The institutions with the highest number of publications were Shanghai Jiao Tong University and Zhejiang University.However,the institution with the most citations was the United States National Cancer Institute.Among authors,Professor Giorgio Trinchieri from the National Institutes of Health has the most local impact in this field.The most cited author was Fan XZ.The results of journal publications showed that the top three journals with the highest number of published papers were Frontiers in Immunology,Cancers,and Frontiers in Oncology.The three most frequently used keywords were gut microbiota,tumor microenvironment,and immunotherapy.CONCLUSION This study systematically elaborates on the research progress related to gut microbiota and TIME over the past decade.Research results indicate that the number of publications has rapidly increased since 2019,with research hotspots including“gut microbiota”,“tumor microenvironment”and“immunotherapy”.Exploring the effects of specific gut microbiota or derived metabolites on the behavior of immune cells in the TIME,regulating the secretion of immune molecules,and influencing immunotherapy are research hotspots and future research directions.
文摘As the global community strives to achieve the Sustainable Development Goals(SDG),bibliometric analysis offers valuable insights into research trends,impact,and collaboration patterns related to these critical areas.We are excited to announce a special issue focused on“Fostering SDG-related Research through the Lens of Bibliometrics.”
文摘AIM:To comprehensively investigate the current state of research on the application of neurotrophic factors in glaucoma therapy and identify potential research hotspots.METHODS:On September 30,2023,a literature search was conducted on Scopus using specific keywords related to neurotrophic factors and glaucoma.Of the 918 articles retrieved,780 met the inclusion criteria.These articles were subsequently analyzed and visualized using Google Sheets,Biblioshiny 3.1,and VosViewer 1.6.18.RESULTS:A total of 780 studies published between 1989 and 2023 were included,and the global publication count showed an upward trend through 2023(projected to continue rising by 2030).The United States,China,Japan,Italy,and Australia were the most significant contributors to the publication output.Research in this field had been published in 313 journals,spanning categories such as pharmacology and drug development,ophthalmology,genetics and gene therapy,and neuroscience.A total of 2622 authors had contributed to these studies,with the most prolific author publishing 14 articles.The focus of research in this field had evolved sequentially from“glutamate”to“CNTF”and“GDNF”,and finally to“optic nerve injury”.Co-occurrence analysis identified five clusters:glaucoma and ocular health,neuroinflammation in ophthalmology,neuroprotection in ophthalmology,ocular drug delivery,and stem cell therapy.Several areas in this field require further exploration,including the neurophysiological mechanisms underlying glaucoma,ocular drug delivery systems,and the clinical value of specific neurotrophic factors.CONCLUSION:This study systematically reviews global research trends on neurotrophic factors in glaucoma therapy,clarifying the current research status and future directions.
文摘BACKGROUND Gastrointestinal endoscopy has been widely used in the diagnosis and treatment of gastrointestinal diseases.A great many of studies on gastrointestinal endoscopy have been done.AIM To analyze the characteristics of top 100 cited articles on gastrointestinal endoscopy.METHODS A bibliometric analysis was conducted.The publications and their features were extracted from the Web of Science Core Collection,Science Citation Index-Expanded database.Excel,Web of Science database and SPSS software were used to perform the statistical description and analysis.VOSviewer software and Map-Chart were responsible for the visualizations.RESULTS The top 100 cited articles were published between 1976 and 2022.The guidelines(52%)and clinical trials(37%)are the main article types,and average publication year of the guidelines is much later than that of the clinical trials(2015 vs 1998).Among the clinical trials,diagnostic study(27.0%),cohort study(21.6%),case series(13.5%)and cross-sectional study(10.8%)account for a large proportion.Average citations of different study types and designs of the enrolled studies are of no significant differences.Most of the 100 articles were published by European authors and recorded by the endoscopic journals(65%).Top journals in medicine,such as the Lancet,New England Journal of Medicine and JAMA,also reported studies in this field.The hot spots of involved diseases include neoplasm or cancer-related diseases,inflammatory diseases,obstructive diseases,gastrointestinal hemorrhage and ulcer.Endoscopic surgery,endoscopic therapy and stent placement are frequently studied.CONCLUSION Our research contributes to delineating the field and identifying the characteristics of the most highly cited articles.It is noteworthy that there is a significantly smaller number of clinical trials included compared to guidelines,indicating potential areas for future high-quality clinical trials.
文摘Accurate estimation of evapotranspiration(ET)is crucial for efficient water resource management,particularly in the face of climate change and increasing water scarcity.This study performs a bibliometric analysis of 352 articles and a systematic review of 35 peer-reviewed papers,selected according to PRISMA guidelines,to evaluate the performance of Hybrid Artificial Neural Networks(HANNs)in ET estimation.The findings demonstrate that HANNs,particularly those combining Multilayer Perceptrons(MLPs),Recurrent Neural Networks(RNNs),and Convolutional Neural Networks(CNNs),are highly effective in capturing the complex nonlinear relationships and tem-poral dependencies characteristic of hydrological processes.These hybrid models,often integrated with optimization algorithms and fuzzy logic frameworks,significantly improve the predictive accuracy and generalization capabilities of ET estimation.The growing adoption of advanced evaluation metrics,such as Kling-Gupta Efficiency(KGE)and Taylor Diagrams,highlights the increasing demand for more robust performance assessments beyond traditional methods.Despite the promising results,challenges remain,particularly regarding model interpretability,computational efficiency,and data scarcity.Future research should prioritize the integration of interpretability techniques,such as attention mechanisms,Local Interpretable Model-Agnostic Explanations(LIME),and feature importance analysis,to enhance model transparency and foster stakeholder trust.Additionally,improving HANN models’scalability and computational efficiency is crucial,especially for large-scale,real-world applications.Approaches such as transfer learning,parallel processing,and hyperparameter optimization will be essential in overcoming these challenges.This study underscores the transformative potential of HANN models for precise ET estimation,particularly in water-scarce and climate-vulnerable regions.By integrating CNNs for automatic feature extraction and leveraging hybrid architectures,HANNs offer considerable advantages for optimizing water management,particularly agriculture.Addressing challenges related to interpretability and scalability will be vital to ensuring the widespread deployment and operational success of HANNs in global water resource management.
基金Supported by National Natural Science Foundation of China,No.81630080,No.82305179,and No.82374181The China Postdoctoral Science Foundation Grant,No.2019M650600+1 种基金The Beijing University of Chinese Medicine“Decoding Traditional Chinese Medicine”Project,No.2023-JYB-JBZD-036The Hefei National Research Center for Physical Sciences at the Microscale,No.KF2021104.
文摘BACKGROUND Hepatic organoid-based modelling,through the elucidation of a range of in vivo biological processes and the recreation of the intricate liver microenvironment,is yielding groundbreaking insights into the pathophysiology and personalized medicine approaches for liver diseases.AIM This study was designed to analyse the global scientific output of hepatic organoid research and assess current achievements and future trends through bibliometric analysis.METHODS Articles were retrieved from the Web of Science Core Collection,and CiteSpace 6.3.R1 was employed to analyse the literature,including outputs,journals,and countries,among others.RESULTS Between 2010 and 2024,a total of 991 articles pertaining to hepatic organoid research were published.The journal Hepatology published the greatest number of papers,and journals with an impact factor greater than 10 constituted 60%of the top 10 journals.The United States and Utrecht University were identified as the most prolific country and institution,respectively.Clevers H emerged as the most prolific author,whereas Huch M had the highest number of cocitations,suggesting that both are ideal candidates for academic collaboration.Research on hepatic organoids has exhibited a progressive shift in focus,evolving from initial investigations into model building,differentiation research in stem cells,bile ducts,and progenitor cells,to a broader spectrum encompassing lipid metabolism,single-cell RNA sequencing,and therapeutic applications.The phrases exhibiting citation bursts from 2022 to 2024 include“drug resistance”,“disease model”,and“patient-derived tumor organoids”.CONCLUSION Research on hepatic organoids has increased over the past decade and is expected to continue to grow.Key research areas include applications for liver diseases and drug development.Future trends likely to gain focus include patient-derived tumour organoids,disease modelling,and personalized medicine.
基金supported by the Special Fund for Science and Technology Innovation Strategy of Guangdong Province,China(2022660500250009604)。
文摘Methane contributes to global warming,and livestock is one of the sources of methane production.However,methane emission studies using bibliometric tools in livestock are lacking.Given the negative impact of climate change on the ecosystem and the rise in methane emissions,it is essential to conduct a bibliometrics study to provide an overview and research trends.We used the Bibliometrix package and VOSviewer to decipher bibliometric indices for methane emissions in cattle farms(MECF).Current dataset were collected from the Web of Science(Core Collection)database,and 8,998 publications were analyzed.The most co-occurring keywords scientists preferred were methane(1,528),greenhouse gas(443),methane emissions(440),and cattle(369).Methane was the most frequently used keyword in the published scientific literature.Thematic evolution of research themes and trend results highlighted carbon dioxide,methane,dairy cattle,cattle,and risk factors during 1999–2017.Chinese Academy of Sciences ranked on top with 485 publications,followed by Agriculture&Agri-Food Canada,University of Colorado,National Oceanic and Atmospheric Administration,and Aarhus University.Chinese Academy of Sciences was also the most cited organization,followed by the University of Colorado,Agriculture&Agri-Food Canada,National Oceanic and Atmospheric Administration,and United States Geological Survey.Source analysis showed that the Science of the Total Environment was cited with the highest total link strength.Science of the Total Environment ranked first in source core 1 with 290 citation frequencies,followed by Journal of Dairy Science with 223 citation frequencies.Currently,no bibliometric study has been conducted on MECF,and to fill this knowledge gap,we carried out this study to highlight methane emissions in cattle farms,aiming at a climate change perspective.In this regard,we focused on the research productivity of countries authors,journals and institutions,co-occurrence of keywords,evolution of research trends,and collaborative networking.Based on relevance degree of centrality,methane emissions and greenhouse gases appeared as basic themes,cattle,and dairy cattle appeared as emerging/declining themes,whereas,methane,greenhouse gas and nitrous oxide appeared to fall amongst basic and motor themes.On the other hand,beef cattle,rumen and dairy cow seem to be between motor and niche themes,and risk factors lie in niche themes.The present bibliometric analysis provides research progress on methane emissions in cattle farms.Current findings may provide a framework for understanding research trends and themes in MECF research.
基金Supported by National Natural Science Foundation of China(Grant Nos.52375447,52305477 and 52105457)the Shandong Provincial Natural Science Foundation of China(Grant Nos.ZR2023QE057,ZR2024QE100 and ZR2024ME255)+2 种基金Qingdao Municipal Science and Technology Planning Park Cultivation Plan(Grant No.23-1-5-yqpy-17-qy)Shandong Provincial Science and Technology SMEs Innovation Capacity Improvement Project(Grant No.2022TSGC1115)the Special Fund of Taishan Scholars Project。
文摘Intelligent manufacturing(IM),a driving force behind the fourth industrial revolution,is reshaping the manufacturing sector by enhancing productivity,efficiency,and sustainability.Despite the rapid technological advancements in IM,comprehensive bibliometric reviews remain limited.This article systematically reviews the latest research in IM,addressing emerging hotspots,key technologies,and their applications across the entire product manufacturing cycle.Bibliometric analysis is employed to identify research trends visualize publication volume,collaboration patterns,research domains,co-citations,and emerging areas of interest.The article then examines key technologies supporting IM,including sensors,the Internet of Things(IoT),big data analytics,cloud computing,artificial intelligence(AI),digital twins,and virtual reality(VR)/augmented reality(AR).Furthermore,it explores the application of these technologies throughout the manufacturing cycle-from intelligent reliability design,material transportation and tracking,to intelligent planning and scheduling,machining and fabrication,monitoring and maintenance,quality inspection and control,warehousing and management,and sustainable green manufacturing—through specific case studies.Lastly,the article discusses future research directions,highlighting the increasing global market and the need for enhanced interdisciplinary collaboration,technological integration,computing power upgrades,and attention to security and privacy in IM.This study provides valuable insights for scholars and serves as a guide for future research and strategic investment decisions,offering a comprehensive view of the IM field.
基金Supported by Key Project of Anhui Provincial Education Department,No.2022AH050486and 2021 High-level Talent Introduction Scientific Project of Anhui University of Chinese Medicine,No.2022rczd005.
文摘BACKGROUND Diabetes has a substantial impact on public health,highlighting the need for novel treatments.Ubiquitination,an intracellular protein modification process,is emerging as a promising strategy for regulating pathological mechanisms.We hypothesize that ubiquitination plays a critical role in the development and progression of diabetes and its complications,and that understanding these mechanisms can lead to new therapeutic approaches.AIM To uncover the research trends and advances in diabetes ubiquitination and its complications,we conducted a bibliometric analysis.METHODS Studies on ubiquitination in diabetes mellitus and its complications were retrieved from the Web of Science Core Collection.Visual mapping analysis was conducted using the CiteSpace software.RESULTS We gathered 791 articles published over the past 23 years,focusing on ubiquitination in diabetes and its associated complications.These articles originated from 54 countries and 386 institutions,with China as the leading contributor.Shanghai Jiao Tong University has the highest number of publications in this field.The most prominent authors contributing to this research area include Wei-Hua Zhang,with Zhang Y being the most frequently cited author.Additionally,The Journal of Biological Chemistry is noted as the most cited in this field.The predominant keywords included expression,activation,oxidative stress,phosphorylation,ubiquitination,degradation,and insulin resistance.CONCLUSION The role of ubiquitination in diabetes and its complications,such as diabetic nephropathy and cardiomyopathy,is a key research focus.However,these areas require further investigations.
基金Supported by the Qilu Medical School Traditional Chinese Medicine Academic School Inheritance Project,No.93 LW[2022]Construction Project of the Inheritance Studio of National Famous Traditional Chinese Medicine Experts,Traditional Chinese Medicine Teaching Letter No.75[2022]Qilu Health and Fitness Talents in 2019,No.3 LWRZ[2020].
文摘BACKGROUND Diabetic foot ulcers(DFUs)are a significant contributor to disability and mortality in diabetic patients.Macrophage polarization and functional regulation are promising areas of research and show therapeutic potential in the field of DFU healing.However,the complex mechanism,the difficulty in clinical translation,and the large heterogeneity present significant challenges.Hence,this study was to comprehensively analyze the publication status and trends of studies on macrophage polarization and DFU healing.AIM To examine the relevant literature on macrophage polarization in DFU healing.METHODS A bibliometric analysis was conducted using the Web of Science database.Relevant literature was retrieved from the Web of Science Core Collection database between 2013 to 2023 using literature visualization and analysis software(VOSviewer and CiteSpace)and bibliometric online platforms.The obtained literature was then subjected to visualization and analysis of different countries/regions,institutions,journals,authors,and keywords to reveal the research’s major trends and focus.RESULTS The number of publications on the role of macrophage polarization in DFU healing increased rapidly from 2013 to 2023,especially in the latter period.Chinese researchers were the most prolific in this field,with 217 publications,while American researchers had been engaged in this field for a longer period.Qian Tan of Nanjing Drum Tower Hospital and Qian Ding of Nanjing University were the first to publish in this field.Shanghai Jiao Tong University was the institution with the most publications(27).The keywords“bone marrow”,“adjustment,replacement,response,tissue repair”,and“activation,repair,differentiation”appeared more frequently.The study of macrophage polarization in DFU healing focused on the regulatory mechanism,gene expression,and other aspects.CONCLUSION This study through the bibliometric method reveals the research trends and development trends in this field of macrophage polarization in DFU healing from 2013 to 2023 in the Web of Science Core Collection database.The key hotspots in this field mainly include the regulation of macrophage activation,gene expression,wound tissue repair,and new wound materials.This study provides references for future research directions.
基金Supported by the National College Students’Innovative Entrepreneurial Training Plan Program,No.202410403067the Innovation and Entrepreneurship Training Program for College Students in Jiangxi Province,No.S202410403035.
文摘BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of global research on BD drug treatment over the last decade.METHODS The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were extracted.Data visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks.The University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this field.The Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.CONCLUSION This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future directions.The study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.
文摘BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is lacking.AIM To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.METHODS The documents related to SSD are obtained from the web of science core collection database(WoSCC),and VOSviewer 1.6.16 from January 1,2000 to December 31,2023,and the WoSCC’s literature analysis wire were used to conduct the biblio-metric analysis.RESULTS A total of 567 documents related to SSD were included,and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research,published in 277 journals.The most productive author,institution,country and journal were Löwe B,University of Hamburg,Germany,and Journal of Psycho-somatic Research respectively.The first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues,which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.CONCLUSION In conclusion,the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria,functional impairment of SSD,and the treatment for SSD.More high-quality studies are needed to assess the diagnosis and treatment of SSD.
基金Supported by the National Natural Science Foundation of China,No.82105018 and No.81903950.
文摘BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.
文摘In this editorial,we comment on the recent article by Fei et al exploring the field of near-infrared spectroscopy(NIRS)research in schizophrenia from a bibliometrics perspective.In recent years,NIRS has shown unique advantages in the auxiliary diagnosis of schizophrenia,and the introduction of bibliometrics has provided a macro perspective for research in this field.Despite the opportunities brought about by these technological developments,remaining challenges require multidi-sciplinary approach to devise a reliable and accurate diagnosis system for schizo-phrenia.Nonetheless,NIRS-assisted technology is expected to contribute to the division of methods for early intervention and treatment of schizophrenia.
