The diagram of Ag-Cu-Bi system was constructed from the investigation of 12 internal sec- tions by DTA heating as well as cooling curves in an atmosphere of dry N_2.The composi- tion of ternary eutectic point melting ...The diagram of Ag-Cu-Bi system was constructed from the investigation of 12 internal sec- tions by DTA heating as well as cooling curves in an atmosphere of dry N_2.The composi- tion of ternary eutectic point melting at 258℃ lies in Ag(5.0)-Cu(0.5)-Bi(94.5) at.-%.The liquiduses of Ag-Cu,Ag-Bi and Cu-Bi binaries were reinvestigated.展开更多
We present a comprehensive analysis of BI CVn,an eclipsing overcontact binary system.New BVR photometric observations,combined with available spectroscopic data,were analyzed simultaneously using the Wilson–Devinney ...We present a comprehensive analysis of BI CVn,an eclipsing overcontact binary system.New BVR photometric observations,combined with available spectroscopic data,were analyzed simultaneously using the Wilson–Devinney method to derive the orbital and physical parameters of the system.The resulting stellar parameters are M1=0.58±0.01M⊙,M2=1.42±0.02M⊙,R1=0.88±0.01R⊙,R2=1.31±0.01R⊙,with an orbital separation of a=2.80±0.01R⊙.Based on all available CCD times of minimum light,including both ground-based and T ESS observations,the(O-C)diagram of BI CVn was analyzed.T he orbital period exhibits a long-term decrease at a rate of-2.3239(±0.0001)×10-8 day yr-1,likely due to mass transfer from the more massive to the less massive component.Superimposed on this trend is a cyclic variation with a period of 56.84±0.08 yr,indicative of a light-travel time effect caused by a third body,whose estimated mass is 0.63±0.02M⊙.Using these derived parameters,we modeled the binary’s evolution through non-conservative processes with the Binary Star Evolution code.The evolutionary tracks of the components were examined in multiple parameter planes,leading to an estimated merger timescale of approximately 2.70 Gyr.展开更多
Interplay between topology and magnetism can give rise to exotic properties in topological materials.Two-dimensional bismuth has been extensively studied owing to its topological states with a strong spin-orbit coupli...Interplay between topology and magnetism can give rise to exotic properties in topological materials.Two-dimensional bismuth has been extensively studied owing to its topological states with a strong spin-orbit coupling,and 1T-VTe_(2)monolayer theoretically predicted to host an intrinsic magnetism as experimentally suggested.In this work,we successfully constructed a vertical heterostructure composed of the two-dimensional Bi(110)monolayer and 1T-VTe_(2)monolayer by using molecular beam epitaxy(MBE).Scanning tunneling microscopy(STM)measurements revealed that the growth of Bi preferably occurs along the step edges of the VTe_(2)monolayer,forming a Bi(110)monolayer on top of the VTe_(2)monolayer next to a peripheral Bi bilayer.The Bi(100)/VTe_(2)heterostructure exhibits a specific lattice registry with a well-defined moiréperiodicity.Scanning tunneling spectroscopy(STS)measurements further unveiled an universal suppression in the local density-of-states at the boundary of the Bi(110)/VTe_(2)bilayer.By examining the atomic structures of Bi(110)boundaries,we found this effect does not originate from the previously proposed atomic reconstruction at the step edge of Bi(110),but is likely related to the magnetic properties of the VTe_(2)monolayer.展开更多
目的:探讨传统开颅手术与神经内镜微创手术对脑出血患者美国国立卫生研究院卒中量表评分(National Institute of Health Stroke Scale Score,NIHSS)及巴塞尔指数评分(Barthel Index Score,BI)的影响。方法:回顾性收集2022年1月至2023年...目的:探讨传统开颅手术与神经内镜微创手术对脑出血患者美国国立卫生研究院卒中量表评分(National Institute of Health Stroke Scale Score,NIHSS)及巴塞尔指数评分(Barthel Index Score,BI)的影响。方法:回顾性收集2022年1月至2023年1月期间本院收治的200例脑出血患者的临床资料。根据治疗方式不同将患者分为对照组(实施传统开颅手术,150例)和观察组(实施神经内镜微创手术,50例)。收集并比较两组术后神经功能恢复情况、术后日常生活活动能力、手术相关指标、术后并发症发生情况。结果:随着术后时间增长,两组NIHSS评分均降低;术后2、3、6、12 m,观察组NIHSS评分均低于对照组(P<0.05)。随着术后时间增长,两组BI评分均提高;术后2、3、6、12 m,观察组BI评分均高于对照组(P<0.05)。观察组手术时间、术后住院时间均短于对照组,术中出血量少于对照组(P<0.05)。观察组术后并发症发生率低于对照组(P<0.05)。结论:与传统开颅手术比较,神经内镜微创手术更有利于促进脑出血患者神经功能恢复、提升日常生活活动能力,且兼具操作时间短、出血量少、住院时间短、并发症发生率低等优势,预后情况良好,值得临床推广应用。展开更多
Background:Inflammation,caused by prolonged hyperglycemia,plays a substantially more important part in the progression of diabetic peripheral neuropathy(DPN).Notably,the MAPK pathway that mediates the Nuclear Factor-k...Background:Inflammation,caused by prolonged hyperglycemia,plays a substantially more important part in the progression of diabetic peripheral neuropathy(DPN).Notably,the MAPK pathway that mediates the Nuclear Factor-kappa B(NF-κB)pathway contributes to inflammation-induced peripheral nerve damage,affecting cell survival.Juan Bi Tong Luo(JBTL),a traditional Chinese medicine(TCM),has demonstrated favorable results in alleviating pain and numbness in patients with DPN;however,whether JBTL exerts its effect through the MAPK mediating NF-κB pathway remains unclear.Methods:This study investigated whether JBTL modulates apoptosis in DPN models and Schwann cells cultured in 100 mM of glucose by MAPK/NF-κB.Results:The JBTL altered inflammation,reduced peripheral nerve tissue damage,and improved cell survival rates by down-regulating MAPK/NF-κB.Conclusion:Our findings demonstrate that the effect of JBTL on DPN is likely mediated by suppressing inflammation induced by the MAPK/NF-κB pathway,thus providing evidence for the clinical efficacy of JBTL in treating DPN.展开更多
Rising temperatures and increased droughts caused by climate change significantly reduce crop yields.Halophytes with different photosynthetic metabolism types have specific mechanisms for resistance to climatic factor...Rising temperatures and increased droughts caused by climate change significantly reduce crop yields.Halophytes with different photosynthetic metabolism types have specific mechanisms for resistance to climatic factors.This study analyzed the morphophysiological,biochemical,and molecular-genetic mechanisms of tolerance and adaptation in halophytes,promising candidates for the restoration of salt affected lands in arid and semi-arid areas.Experiments under drought(D)and elevated temperature(eT),as well as their combined action(eT+D),were performed on Atriplex verrucifera M.Bied.(C_(3)plant)and Climacoptera crassa(M.Bieb.)Botsch.(C_(4)-NAD-ME plant)with different types of photosynthesis.The activity of photosystem I(PSI)and the efficiency of photosystem II(PSII)were measured,along with the expression of genes involved in the light(psaA,psaB,psbA,CAB,Fd1,PGR5,and ndhH)and dark(rbcL,Ppc2,and PPDK)reactions of photosynthesis.The content of key carboxylating enzymes ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco)and phosphoenolpyruvate carboxylase(PEPC),as well as the photorespiration enzyme glycine decarboxylase(GDC),were assessed.Plant growth and water-salt balance parameters,and activity of enzymes in the malate dehydrogenase(MDH)system nicotinamide adenine dinucleotide(phosphate)(NAD(P))-MDH and NAD(P)-malic enzyme(ME)were also examined.A multivariate analysis of the experimental results revealed that A.verrucifera and C.crassa were both resistant to the effects of these climatic stressors.The tolerance mechanisms of both species were significantly influenced by a high level of photosynthetic plasticity.Nevertheless,differences were observed in the protective mechanisms underlying tolerance.In the C_(3)species,dissipative processes associated with non-photochemical quenching(NPQ)of PSII and MDH system enzymes(malate valves)were activated,particularly under osmotic stress.The negative effects in the C_(3)plants were caused by the combined action of eT+D,which was compensated by an increased expression of rbcL,psaA,CAB,and especially PGR5,i.e.,genes encoding Rubisco large subunit and PSI components:apoproteins A,chlorophyll a/b-associated protein(CAB)of light-harvesting complex,and proton gradient regulation 5(PGR5)protein of the main pathway of cyclic electron transport(CET)around PSI.In C_(4)species,the protective MDH complex was expressed to a lesser extent,but activation of the C_(4)carbon-concentrating mechanism(CCM)and upregulation of PGR5 expression were observed,particularly under the individual action of the factors.Under the combined stress of eT+D,C.crassa exhibited a synergistic effect,where the increase in NPQ level and NAD-ME activity,as well as decrease in NADP-ME activity was less pronounced compared with the effect of singular factors.Comparative physiological,biochemical,and molecular analyses of how C_(3)and C_(4)species response to individual and combined climatic factors provide new insights into sustainable plant adaptation strategies in the face of global climate change.Considering the high nutritional value of these two fodder species,a technological approach could be developed to improve the productivity of salt affected lands.展开更多
The existence of the"stomach-knee axis"and the potential independent association between"Helicobacter pylori(Hp)infection and knee osteoarthritis(KOA)"have been substantiated through multiple lines...The existence of the"stomach-knee axis"and the potential independent association between"Helicobacter pylori(Hp)infection and knee osteoarthritis(KOA)"have been substantiated through multiple lines of evidence,including epidemiological studies of the"stomach-knee axis",investigations into the pathological mechanisms linking"Hp infection and arthritis",as well as research on co-treatment drugs and the anti-inflammatory mechanisms relevant to"gastritis and arthritis".The investigation into"stomach and knee joint treatment"is grounded in the concept that the"stomach-knee axis"aligns with the"combined bi of body constituents and zang organs"theory.Clinical cases have demonstrated that therapeutic strategies of"stomach and knee joint treatment"can mitigate KOA damage by modulating the"stomach-knee axis"and eradicating Hp infection in the stomach.This study aims to contribute novel insights into the cross-system treatment of KOA.Further investigation into the"stomach-knee axis"may yield innovative strategies for the prevention and management of KOA,potentially through the eradication of Hp.展开更多
Bi2O3-ZnO-B2O3 system glass is a kind of lead-free low melting sealing glasses. The structure of Bi2O3-ZnO-B2O3 system low-melting sealing glass was investigated by DSC, FT-IR, XRD and SEM. The results show that with ...Bi2O3-ZnO-B2O3 system glass is a kind of lead-free low melting sealing glasses. The structure of Bi2O3-ZnO-B2O3 system low-melting sealing glass was investigated by DSC, FT-IR, XRD and SEM. The results show that with the increase of B2O3 content, the transition temperature Tg and softening temperature Tf of Bi2O3-ZnO-B2O3 system low-melting sealing glasses increase, which leads to the liquid phase precipitation temperature increasing and promotes the structure stability in the glass. With increasing the heat treatment temperature, a large number of liquid phases appear in samples and the sinter efficiency of the samples increases. The FT-IR spectra of the glasses show the presence of some bands that are assigned to vibrations of Bi--O bond from [BO3] pyramidal and [BiO6] octahedral units and B--O from [BO3] and [BO4] units. With the decrease of B203 content, the crystallization tendency of the glass increases. In glass samples Bl and B〉 crystallization starts at 460 ℃ and 540 ℃, respectively. Both of them precipitate Bi24B2O39 phases.展开更多
This paper reports a novel micro-blast driven manufacturing process for micro-forming of Aluminum foils. The micro-blast is realized by using a nanoenergetic material system comprising of Bi_2O_3 microrods and aluminu...This paper reports a novel micro-blast driven manufacturing process for micro-forming of Aluminum foils. The micro-blast is realized by using a nanoenergetic material system comprising of Bi_2O_3 microrods and aluminum particles. There is an enhanced need of forming of thin aluminum foil structures in small regions from point of view of drug packaging etc. The process developed caters to this need by using a single shot forming process using a micro-blast source. The micro-blast that is generated from an energetic composite system is made highly tunable by modulating the peak pressure generated through the blasting process and their impact in micro-forming of thin aluminum foils is observed through parametric studies. The engineering challenge involved in these experiments is to tune the blast pressure properties in order to address the forming of thin metal sheets with limiting boundary values as defined by the failure criteria. A variety of characterization techniques related to a thorough analysis of the synthesized material viz. X-ray diffraction(XRD), Scanning Electron Microscopy(SEM) etc, are used to tune the functional properties like gauge blast pressure etc, of material system. We have found a material system that can generate a maximum peak pressure of 73.8 MPa with pressurization rate of 2460 GPas^(-1) and that is able to accomplish micro-forming on thin metal foils(around 0.3 mm thickness). Experimental investigations demonstrate that tunabilty aspect of the energetic composites when exercised can enable variant processes such as embossing, coining, drilling etc. which may be of significant utility to drug packaging industries. A proper mathematical modeling of the forming process and critical process parameters therein have also been detailed.展开更多
文摘The diagram of Ag-Cu-Bi system was constructed from the investigation of 12 internal sec- tions by DTA heating as well as cooling curves in an atmosphere of dry N_2.The composi- tion of ternary eutectic point melting at 258℃ lies in Ag(5.0)-Cu(0.5)-Bi(94.5) at.-%.The liquiduses of Ag-Cu,Ag-Bi and Cu-Bi binaries were reinvestigated.
基金a project supported by the Scientific and Technological Research Council of Türkiye (TüB?TAK) under grant No.114F166
文摘We present a comprehensive analysis of BI CVn,an eclipsing overcontact binary system.New BVR photometric observations,combined with available spectroscopic data,were analyzed simultaneously using the Wilson–Devinney method to derive the orbital and physical parameters of the system.The resulting stellar parameters are M1=0.58±0.01M⊙,M2=1.42±0.02M⊙,R1=0.88±0.01R⊙,R2=1.31±0.01R⊙,with an orbital separation of a=2.80±0.01R⊙.Based on all available CCD times of minimum light,including both ground-based and T ESS observations,the(O-C)diagram of BI CVn was analyzed.T he orbital period exhibits a long-term decrease at a rate of-2.3239(±0.0001)×10-8 day yr-1,likely due to mass transfer from the more massive to the less massive component.Superimposed on this trend is a cyclic variation with a period of 56.84±0.08 yr,indicative of a light-travel time effect caused by a third body,whose estimated mass is 0.63±0.02M⊙.Using these derived parameters,we modeled the binary’s evolution through non-conservative processes with the Binary Star Evolution code.The evolutionary tracks of the components were examined in multiple parameter planes,leading to an estimated merger timescale of approximately 2.70 Gyr.
基金financially supported by the National Key Research and Development Program of China(Grant No.2021YFA1400403)the National Natural Science Foundation of China(Grant Nos.12374183,92165205)+2 种基金the Natural Science Foundation of Jiangsu Province(Grant No.BK20233001)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0302800)the Fundamental Research Funds for the Central Universities(Grant No.020414380207).
文摘Interplay between topology and magnetism can give rise to exotic properties in topological materials.Two-dimensional bismuth has been extensively studied owing to its topological states with a strong spin-orbit coupling,and 1T-VTe_(2)monolayer theoretically predicted to host an intrinsic magnetism as experimentally suggested.In this work,we successfully constructed a vertical heterostructure composed of the two-dimensional Bi(110)monolayer and 1T-VTe_(2)monolayer by using molecular beam epitaxy(MBE).Scanning tunneling microscopy(STM)measurements revealed that the growth of Bi preferably occurs along the step edges of the VTe_(2)monolayer,forming a Bi(110)monolayer on top of the VTe_(2)monolayer next to a peripheral Bi bilayer.The Bi(100)/VTe_(2)heterostructure exhibits a specific lattice registry with a well-defined moiréperiodicity.Scanning tunneling spectroscopy(STS)measurements further unveiled an universal suppression in the local density-of-states at the boundary of the Bi(110)/VTe_(2)bilayer.By examining the atomic structures of Bi(110)boundaries,we found this effect does not originate from the previously proposed atomic reconstruction at the step edge of Bi(110),but is likely related to the magnetic properties of the VTe_(2)monolayer.
文摘目的:探讨传统开颅手术与神经内镜微创手术对脑出血患者美国国立卫生研究院卒中量表评分(National Institute of Health Stroke Scale Score,NIHSS)及巴塞尔指数评分(Barthel Index Score,BI)的影响。方法:回顾性收集2022年1月至2023年1月期间本院收治的200例脑出血患者的临床资料。根据治疗方式不同将患者分为对照组(实施传统开颅手术,150例)和观察组(实施神经内镜微创手术,50例)。收集并比较两组术后神经功能恢复情况、术后日常生活活动能力、手术相关指标、术后并发症发生情况。结果:随着术后时间增长,两组NIHSS评分均降低;术后2、3、6、12 m,观察组NIHSS评分均低于对照组(P<0.05)。随着术后时间增长,两组BI评分均提高;术后2、3、6、12 m,观察组BI评分均高于对照组(P<0.05)。观察组手术时间、术后住院时间均短于对照组,术中出血量少于对照组(P<0.05)。观察组术后并发症发生率低于对照组(P<0.05)。结论:与传统开颅手术比较,神经内镜微创手术更有利于促进脑出血患者神经功能恢复、提升日常生活活动能力,且兼具操作时间短、出血量少、住院时间短、并发症发生率低等优势,预后情况良好,值得临床推广应用。
基金funded by grants from the Suzhou Gusu Health Talents Project(grant No.GSWS2024050 to Liu W)Natural Science Foundation Project of Nanjing University of Chinese Medicine(grant No.XZR2021043 to Liu W and grant No.XZR2023021 to Huang F)+1 种基金Suzhou Science Education Health Youth Project(grant No.KJXW2021046 to Liu W)Suzhou Major Disease Multi-center Clinical Research Project(grant No.DZXYJ202410 to Huang F).
文摘Background:Inflammation,caused by prolonged hyperglycemia,plays a substantially more important part in the progression of diabetic peripheral neuropathy(DPN).Notably,the MAPK pathway that mediates the Nuclear Factor-kappa B(NF-κB)pathway contributes to inflammation-induced peripheral nerve damage,affecting cell survival.Juan Bi Tong Luo(JBTL),a traditional Chinese medicine(TCM),has demonstrated favorable results in alleviating pain and numbness in patients with DPN;however,whether JBTL exerts its effect through the MAPK mediating NF-κB pathway remains unclear.Methods:This study investigated whether JBTL modulates apoptosis in DPN models and Schwann cells cultured in 100 mM of glucose by MAPK/NF-κB.Results:The JBTL altered inflammation,reduced peripheral nerve tissue damage,and improved cell survival rates by down-regulating MAPK/NF-κB.Conclusion:Our findings demonstrate that the effect of JBTL on DPN is likely mediated by suppressing inflammation induced by the MAPK/NF-κB pathway,thus providing evidence for the clinical efficacy of JBTL in treating DPN.
基金supported by the state assignment of Ministry of Science and Higher Education of the Russian Federation(122042700044-6)the Science and Technology Research Partnership for Sustainable Development(SATREPS)project(JPMJSA2001).
文摘Rising temperatures and increased droughts caused by climate change significantly reduce crop yields.Halophytes with different photosynthetic metabolism types have specific mechanisms for resistance to climatic factors.This study analyzed the morphophysiological,biochemical,and molecular-genetic mechanisms of tolerance and adaptation in halophytes,promising candidates for the restoration of salt affected lands in arid and semi-arid areas.Experiments under drought(D)and elevated temperature(eT),as well as their combined action(eT+D),were performed on Atriplex verrucifera M.Bied.(C_(3)plant)and Climacoptera crassa(M.Bieb.)Botsch.(C_(4)-NAD-ME plant)with different types of photosynthesis.The activity of photosystem I(PSI)and the efficiency of photosystem II(PSII)were measured,along with the expression of genes involved in the light(psaA,psaB,psbA,CAB,Fd1,PGR5,and ndhH)and dark(rbcL,Ppc2,and PPDK)reactions of photosynthesis.The content of key carboxylating enzymes ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco)and phosphoenolpyruvate carboxylase(PEPC),as well as the photorespiration enzyme glycine decarboxylase(GDC),were assessed.Plant growth and water-salt balance parameters,and activity of enzymes in the malate dehydrogenase(MDH)system nicotinamide adenine dinucleotide(phosphate)(NAD(P))-MDH and NAD(P)-malic enzyme(ME)were also examined.A multivariate analysis of the experimental results revealed that A.verrucifera and C.crassa were both resistant to the effects of these climatic stressors.The tolerance mechanisms of both species were significantly influenced by a high level of photosynthetic plasticity.Nevertheless,differences were observed in the protective mechanisms underlying tolerance.In the C_(3)species,dissipative processes associated with non-photochemical quenching(NPQ)of PSII and MDH system enzymes(malate valves)were activated,particularly under osmotic stress.The negative effects in the C_(3)plants were caused by the combined action of eT+D,which was compensated by an increased expression of rbcL,psaA,CAB,and especially PGR5,i.e.,genes encoding Rubisco large subunit and PSI components:apoproteins A,chlorophyll a/b-associated protein(CAB)of light-harvesting complex,and proton gradient regulation 5(PGR5)protein of the main pathway of cyclic electron transport(CET)around PSI.In C_(4)species,the protective MDH complex was expressed to a lesser extent,but activation of the C_(4)carbon-concentrating mechanism(CCM)and upregulation of PGR5 expression were observed,particularly under the individual action of the factors.Under the combined stress of eT+D,C.crassa exhibited a synergistic effect,where the increase in NPQ level and NAD-ME activity,as well as decrease in NADP-ME activity was less pronounced compared with the effect of singular factors.Comparative physiological,biochemical,and molecular analyses of how C_(3)and C_(4)species response to individual and combined climatic factors provide new insights into sustainable plant adaptation strategies in the face of global climate change.Considering the high nutritional value of these two fodder species,a technological approach could be developed to improve the productivity of salt affected lands.
基金Supported by Discipline Construction Project of Shanxi University of Chinese Medicine—Internal Medicine of Traditional Chinese Medicine(2025XK02).
文摘The existence of the"stomach-knee axis"and the potential independent association between"Helicobacter pylori(Hp)infection and knee osteoarthritis(KOA)"have been substantiated through multiple lines of evidence,including epidemiological studies of the"stomach-knee axis",investigations into the pathological mechanisms linking"Hp infection and arthritis",as well as research on co-treatment drugs and the anti-inflammatory mechanisms relevant to"gastritis and arthritis".The investigation into"stomach and knee joint treatment"is grounded in the concept that the"stomach-knee axis"aligns with the"combined bi of body constituents and zang organs"theory.Clinical cases have demonstrated that therapeutic strategies of"stomach and knee joint treatment"can mitigate KOA damage by modulating the"stomach-knee axis"and eradicating Hp infection in the stomach.This study aims to contribute novel insights into the cross-system treatment of KOA.Further investigation into the"stomach-knee axis"may yield innovative strategies for the prevention and management of KOA,potentially through the eradication of Hp.
基金Project(50272043) supported by the National Natural Science Foundation of China
文摘Bi2O3-ZnO-B2O3 system glass is a kind of lead-free low melting sealing glasses. The structure of Bi2O3-ZnO-B2O3 system low-melting sealing glass was investigated by DSC, FT-IR, XRD and SEM. The results show that with the increase of B2O3 content, the transition temperature Tg and softening temperature Tf of Bi2O3-ZnO-B2O3 system low-melting sealing glasses increase, which leads to the liquid phase precipitation temperature increasing and promotes the structure stability in the glass. With increasing the heat treatment temperature, a large number of liquid phases appear in samples and the sinter efficiency of the samples increases. The FT-IR spectra of the glasses show the presence of some bands that are assigned to vibrations of Bi--O bond from [BO3] pyramidal and [BiO6] octahedral units and B--O from [BO3] and [BO4] units. With the decrease of B203 content, the crystallization tendency of the glass increases. In glass samples Bl and B〉 crystallization starts at 460 ℃ and 540 ℃, respectively. Both of them precipitate Bi24B2O39 phases.
基金support provided by Boeing India to Indian Institute of Technology Kanpur,IndiaTEQIP funding from Government of India provided to G.B.Pant Institute of Engineering&Technology Pauri-Garhwal India
文摘This paper reports a novel micro-blast driven manufacturing process for micro-forming of Aluminum foils. The micro-blast is realized by using a nanoenergetic material system comprising of Bi_2O_3 microrods and aluminum particles. There is an enhanced need of forming of thin aluminum foil structures in small regions from point of view of drug packaging etc. The process developed caters to this need by using a single shot forming process using a micro-blast source. The micro-blast that is generated from an energetic composite system is made highly tunable by modulating the peak pressure generated through the blasting process and their impact in micro-forming of thin aluminum foils is observed through parametric studies. The engineering challenge involved in these experiments is to tune the blast pressure properties in order to address the forming of thin metal sheets with limiting boundary values as defined by the failure criteria. A variety of characterization techniques related to a thorough analysis of the synthesized material viz. X-ray diffraction(XRD), Scanning Electron Microscopy(SEM) etc, are used to tune the functional properties like gauge blast pressure etc, of material system. We have found a material system that can generate a maximum peak pressure of 73.8 MPa with pressurization rate of 2460 GPas^(-1) and that is able to accomplish micro-forming on thin metal foils(around 0.3 mm thickness). Experimental investigations demonstrate that tunabilty aspect of the energetic composites when exercised can enable variant processes such as embossing, coining, drilling etc. which may be of significant utility to drug packaging industries. A proper mathematical modeling of the forming process and critical process parameters therein have also been detailed.
