Five compounds including 2 benzene derivatives, 2 terpenoids and 1 sterol were separated by various separation methods such as positive silica gel, Sephadex LH-20 and Rp-18 gel from higher fungi Phellinus rhabarbarin...Five compounds including 2 benzene derivatives, 2 terpenoids and 1 sterol were separated by various separation methods such as positive silica gel, Sephadex LH-20 and Rp-18 gel from higher fungi Phellinus rhabarbarinus （Berk.） G. Cunn. Their structures were elucidated on the basis of nuclear magnetic resonance （NMR） spectroscopy and other methods. All the compounds were separated from this higher fungus for the first time.展开更多
Tremella fuciformis Berk(TF)is an edible fungus with multiple nutritional values,renowned for its antiinflammatory and immunomodulatory properties.This research aimed to elucidate the mechanism by which TF regulates d...Tremella fuciformis Berk(TF)is an edible fungus with multiple nutritional values,renowned for its antiinflammatory and immunomodulatory properties.This research aimed to elucidate the mechanism by which TF regulates depressive symptoms in chronic unpredictable mild stress(CUMS)mice.CUMS modeling was conducted on 6-week-old C57BL/6 male mice,which were subsequently evaluated for depression-like behavior.Immunofluorescence(IF)staining,intestinal microbiota analysis,metabolomics analysis,and Western blot were utilized to investigate the underlying mechanisms.TF significantly mitigated depression-like behaviors and reversed the reduction of synaptophysin(SYN)and postsynaptic density-95(PSD-95)in the brain hippocampus.Furthermore,the expression level of brain-derived neurotrophic factor(BDNF)was significantly upregulated.The antidepressant effect of TF may be ascribed to its anti-inflammatory properties.Further investigation disclosed that TF significantly repressed microglia and astrocyte activation,as well as the phosphorylation of nuclear transcription factor-κB(NF-κB)and inhibitor of NF-κB(IκB)in the brain,while reducing the production of interleukin-6(IL-6),interleukin-1 beta(IL-1β)and tumor necrosis factor-alpha(TNF-α).TF may modulate neuroinflammation by inhibiting NF-κB signaling,thereby exerting an antidepressant effect,suggesting TF as a potential candidate for the prevention and treatment of depression.展开更多
以葡萄霜霉病[Plasmopara viticola(Berk et Curt.)Burl.&de Toni]为监测对象,对辽宁省5个葡萄主栽地区的霜霉病流行情况进行了系统监测。结果表明,葡萄霜霉病的发生逐年加重,其中2016年该病害成灾严重。针对葡萄霜霉病流行特点,结...以葡萄霜霉病[Plasmopara viticola(Berk et Curt.)Burl.&de Toni]为监测对象,对辽宁省5个葡萄主栽地区的霜霉病流行情况进行了系统监测。结果表明,葡萄霜霉病的发生逐年加重,其中2016年该病害成灾严重。针对葡萄霜霉病流行特点,结合病害监测情况,分析了未来葡萄霜霉病的发生趋势和防控对策,为该病的流行预测及防治决策提供借鉴参考。展开更多
冬虫夏草[Cordyceps sinensis(Ber K.)Sacc.]菌培养过程中,蝙蝠蛾拟青霉菌株SH-1的菌丝产生粉红色变化的现象,粉红菌株与SH-1菌株形态上存在很大差异,为查明产生的原因,在单因素试验基础上考察培养时间、培养温度、光照、p H和装液量对...冬虫夏草[Cordyceps sinensis(Ber K.)Sacc.]菌培养过程中,蝙蝠蛾拟青霉菌株SH-1的菌丝产生粉红色变化的现象,粉红菌株与SH-1菌株形态上存在很大差异,为查明产生的原因,在单因素试验基础上考察培养时间、培养温度、光照、p H和装液量对粉红色变化的影响,通过响应面法优化冬虫夏草真菌的培养环境,分析影响粉红色变化的关键因素。结果表明,产生粉红变化的最适培养条件为培养时间80 d、培养温度20.55℃、p H 7.51、装液量250 m L,在此培养基条件下,粉红菌株ZH-1产生概率为35.14%;得出菌株ZH-1的最大得率培养条件为培养时间80 d、培养温度为22.25℃、p H 6.89、装液量250 m L,在此培养基条件下,粉红菌株ZH-1得率为8.95%。展开更多
基金Supported by the Education Scientific Research Project for Middle-age and Young Teachers of Fujian Province(JA15453)Science and Technology Planning Project of Putian City[2014S02(3)]Scientific Research Projects of Putian University(2014053,2015076)~~
文摘Five compounds including 2 benzene derivatives, 2 terpenoids and 1 sterol were separated by various separation methods such as positive silica gel, Sephadex LH-20 and Rp-18 gel from higher fungi Phellinus rhabarbarinus （Berk.） G. Cunn. Their structures were elucidated on the basis of nuclear magnetic resonance （NMR） spectroscopy and other methods. All the compounds were separated from this higher fungus for the first time.
基金funded by the earmarked fund for Edible Mushroom(CARS-20).
文摘Tremella fuciformis Berk(TF)is an edible fungus with multiple nutritional values,renowned for its antiinflammatory and immunomodulatory properties.This research aimed to elucidate the mechanism by which TF regulates depressive symptoms in chronic unpredictable mild stress(CUMS)mice.CUMS modeling was conducted on 6-week-old C57BL/6 male mice,which were subsequently evaluated for depression-like behavior.Immunofluorescence(IF)staining,intestinal microbiota analysis,metabolomics analysis,and Western blot were utilized to investigate the underlying mechanisms.TF significantly mitigated depression-like behaviors and reversed the reduction of synaptophysin(SYN)and postsynaptic density-95(PSD-95)in the brain hippocampus.Furthermore,the expression level of brain-derived neurotrophic factor(BDNF)was significantly upregulated.The antidepressant effect of TF may be ascribed to its anti-inflammatory properties.Further investigation disclosed that TF significantly repressed microglia and astrocyte activation,as well as the phosphorylation of nuclear transcription factor-κB(NF-κB)and inhibitor of NF-κB(IκB)in the brain,while reducing the production of interleukin-6(IL-6),interleukin-1 beta(IL-1β)and tumor necrosis factor-alpha(TNF-α).TF may modulate neuroinflammation by inhibiting NF-κB signaling,thereby exerting an antidepressant effect,suggesting TF as a potential candidate for the prevention and treatment of depression.
文摘以葡萄霜霉病[Plasmopara viticola(Berk et Curt.)Burl.&de Toni]为监测对象,对辽宁省5个葡萄主栽地区的霜霉病流行情况进行了系统监测。结果表明,葡萄霜霉病的发生逐年加重,其中2016年该病害成灾严重。针对葡萄霜霉病流行特点,结合病害监测情况,分析了未来葡萄霜霉病的发生趋势和防控对策,为该病的流行预测及防治决策提供借鉴参考。
文摘冬虫夏草[Cordyceps sinensis(Ber K.)Sacc.]菌培养过程中,蝙蝠蛾拟青霉菌株SH-1的菌丝产生粉红色变化的现象,粉红菌株与SH-1菌株形态上存在很大差异,为查明产生的原因,在单因素试验基础上考察培养时间、培养温度、光照、p H和装液量对粉红色变化的影响,通过响应面法优化冬虫夏草真菌的培养环境,分析影响粉红色变化的关键因素。结果表明,产生粉红变化的最适培养条件为培养时间80 d、培养温度20.55℃、p H 7.51、装液量250 m L,在此培养基条件下,粉红菌株ZH-1产生概率为35.14%;得出菌株ZH-1的最大得率培养条件为培养时间80 d、培养温度为22.25℃、p H 6.89、装液量250 m L,在此培养基条件下,粉红菌株ZH-1得率为8.95%。
