Benincasae Exocarpium(BE,Dongguapi in Chinese),as the dried outer pericarp of Benincasa hispida(wax gourd)in Cucurbitaceae family,is one of traditional Chinese medicines with the same origin as medicine and food.Up to...Benincasae Exocarpium(BE,Dongguapi in Chinese),as the dried outer pericarp of Benincasa hispida(wax gourd)in Cucurbitaceae family,is one of traditional Chinese medicines with the same origin as medicine and food.Up to now,43 compounds were isolated from BE,including flavonoids,alkaloids,tannins,phenolic acids,soluble fiber and carbohydrates.Modern pharmacological studies and clinical practice showed that BE has diuretic,hypolipidemic effects,hypoglycemic,antioxidant,antibacterial,and other effects.The folk uses,functional factors,pharmacological activities,patents and clinical applications of BE were reviewed in this paper.In addition,the paper also discussed the current problems for the further studies.The information summarized in this paper provides valuable clues for the comprehensive utilization of medicine and food resources and gives a scientific basis for the development of medicinal plants of BE.展开更多
Citrus peels have high flavonoids known for potent pharmaceutical and food applications.The present study explores the infusion of citrus peel polyphenols(CPP)into ash gourd(Benincasa hispida)through vacuum impregnati...Citrus peels have high flavonoids known for potent pharmaceutical and food applications.The present study explores the infusion of citrus peel polyphenols(CPP)into ash gourd(Benincasa hispida)through vacuum impregnation(VI).The intent was to functionalize ash gourd for diversifying its food use.Vacuum infused ash gourd(VIAG)cubes were evaluated for physicochemical parameters,total phenolic content(TPC),total flavonoid content(TFC),antioxidant activity(AOX),and sensory quality.The VI process was optimized through Box-Behnken Design(BBD)of response surface methodology(RSM),considering blanching time,vacuum pressure and vacuum time as independent variables,and TPC,TFC and AOX as dependent variables.At optimized conditions of blanching pre-treatment(2.21 min),vacuum pressure(432.31 mbar)and time(28.18 min),there was∼300%increase in TPC and AOX.Peleg model validated the mass transfer kinetics for TPC.Sensory evaluation through descriptive analysis revealed no perceived bitterness in VIAG.Overall,it seems that VI is a promising tool for functionalization of ash gourd with bioactives.展开更多
Limosilactobacillus reuteri is a resident probiotic in the intestines of animals with strong environmental adaptability.In the current study,to elucidate the adaptation strategies of L.reuteri to the intestine of mice...Limosilactobacillus reuteri is a resident probiotic in the intestines of animals with strong environmental adaptability.In the current study,to elucidate the adaptation strategies of L.reuteri to the intestine of mice supplemented with three dietary components(oil,peptide and cellulose),whole genome resequencing and determination of intracellular metabolites were carried out.The resequencing results showed that L.reuteri TO60(LR-TO)from the intestines of mice supplemented with high docosahexaenoic acid(DHA)tuna oil,or fermented Benincasa hispida culture(L.reuteri FB151,abbreviated as LR-FB)had relatively consistent single nucleotide polymorphisms(SNPs)and insertions and deletions(InDels),and those of L.reuteri from the intestines of mice supplemented with Rhopilema esculentum polypeptides(L.reuteri RE225,abbreviated as LR-RE)were quite different from them.The KEGG functional annotation of resequencing and the intracellular metabolites suggested that in all of the L.reuteri adapted to the intestinal environment mainly by regulating carbohydrate metabolism and membrane transport metabolic pathways.However,there were still some differences in their genes and metabolites,which may be related to the changes in the intestinal environment caused by three different types of dietary interventions.Our study analyzed the adaptation mechanism of L.reuteri to different isolated sources at the genetic level and metabolic level,which is helpful to clarify the adaptation strategies of probiotics to the intestinal environment,and provide supplementary information for the use of dietary nutritional supplements.展开更多
基金supported by the National Natural Science Foundation of China(No.81673693)Tianjin Intelligent Manufacturing Special Project of China(No.20201178)for financial support.
文摘Benincasae Exocarpium(BE,Dongguapi in Chinese),as the dried outer pericarp of Benincasa hispida(wax gourd)in Cucurbitaceae family,is one of traditional Chinese medicines with the same origin as medicine and food.Up to now,43 compounds were isolated from BE,including flavonoids,alkaloids,tannins,phenolic acids,soluble fiber and carbohydrates.Modern pharmacological studies and clinical practice showed that BE has diuretic,hypolipidemic effects,hypoglycemic,antioxidant,antibacterial,and other effects.The folk uses,functional factors,pharmacological activities,patents and clinical applications of BE were reviewed in this paper.In addition,the paper also discussed the current problems for the further studies.The information summarized in this paper provides valuable clues for the comprehensive utilization of medicine and food resources and gives a scientific basis for the development of medicinal plants of BE.
基金the Division of Horticulture and Division of Agricultural Chemicals and,ICAR-IARI,New Delhi-110012,India,for providing the fruits and research facilities.
文摘Citrus peels have high flavonoids known for potent pharmaceutical and food applications.The present study explores the infusion of citrus peel polyphenols(CPP)into ash gourd(Benincasa hispida)through vacuum impregnation(VI).The intent was to functionalize ash gourd for diversifying its food use.Vacuum infused ash gourd(VIAG)cubes were evaluated for physicochemical parameters,total phenolic content(TPC),total flavonoid content(TFC),antioxidant activity(AOX),and sensory quality.The VI process was optimized through Box-Behnken Design(BBD)of response surface methodology(RSM),considering blanching time,vacuum pressure and vacuum time as independent variables,and TPC,TFC and AOX as dependent variables.At optimized conditions of blanching pre-treatment(2.21 min),vacuum pressure(432.31 mbar)and time(28.18 min),there was∼300%increase in TPC and AOX.Peleg model validated the mass transfer kinetics for TPC.Sensory evaluation through descriptive analysis revealed no perceived bitterness in VIAG.Overall,it seems that VI is a promising tool for functionalization of ash gourd with bioactives.
基金sponsored by the Natural Science Foundation of Zhejiang Province(LY19C010003)the Natural Science Foundation of Zhejiang Province(LQ22D060002)+1 种基金the Fund of State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products(ZS20190105)the K.C.Wong Magna Fund of Ningbo University.
文摘Limosilactobacillus reuteri is a resident probiotic in the intestines of animals with strong environmental adaptability.In the current study,to elucidate the adaptation strategies of L.reuteri to the intestine of mice supplemented with three dietary components(oil,peptide and cellulose),whole genome resequencing and determination of intracellular metabolites were carried out.The resequencing results showed that L.reuteri TO60(LR-TO)from the intestines of mice supplemented with high docosahexaenoic acid(DHA)tuna oil,or fermented Benincasa hispida culture(L.reuteri FB151,abbreviated as LR-FB)had relatively consistent single nucleotide polymorphisms(SNPs)and insertions and deletions(InDels),and those of L.reuteri from the intestines of mice supplemented with Rhopilema esculentum polypeptides(L.reuteri RE225,abbreviated as LR-RE)were quite different from them.The KEGG functional annotation of resequencing and the intracellular metabolites suggested that in all of the L.reuteri adapted to the intestinal environment mainly by regulating carbohydrate metabolism and membrane transport metabolic pathways.However,there were still some differences in their genes and metabolites,which may be related to the changes in the intestinal environment caused by three different types of dietary interventions.Our study analyzed the adaptation mechanism of L.reuteri to different isolated sources at the genetic level and metabolic level,which is helpful to clarify the adaptation strategies of probiotics to the intestinal environment,and provide supplementary information for the use of dietary nutritional supplements.
