cases of postherpetic neuralgia were treated with arranged electro acupuncture and 30 cases with medicine as control. All cases were HIV carriers. The 6 point behavioral rating scale (BRS 6) was used to observe the ef...cases of postherpetic neuralgia were treated with arranged electro acupuncture and 30 cases with medicine as control. All cases were HIV carriers. The 6 point behavioral rating scale (BRS 6) was used to observe the effect before and after treatment. The results indicate arranged electro acupuncture can cure or reduce the severe pain of postherpetic neuralgia of HIV carriers and the effect was better than medicine.展开更多
To quantitatively evaluate severity of behavioral and psychological symptoms of dementia(BPSD)for vascular dementia(VD).Changes of 51 patients with VD in BPSD between the first and 24th week were assessed using the Ne...To quantitatively evaluate severity of behavioral and psychological symptoms of dementia(BPSD)for vascular dementia(VD).Changes of 51 patients with VD in BPSD between the first and 24th week were assessed using the Neuropsychiatric Inventory(NPI)and the behavioral pathology in Alzheimer’s disease(BEHAVE-AD)rating scale,in detrended fluctuation analysis(DFA)represented by diurnal activity(DA),evening activity(EA),and nocturnal activity(NA),and the relationships were analyzed.The subscores of activity disturbances,diurnal rhythm disturbances,and anxieties and phobias in the BEHAVE-AD score,and that of agitation,irritability,and sleep disorder in the NPI score were significantly increased compared with the first week,as was for the changes for EA in the DFA value.A linear correlation was observed between the changes of activity disturbances plus anxieties and phobias,and those of DA,and between the development of diurnal rhythm and those of EA,the vehement and autism scores and those of DA,and the difference in sleep disorder scores and those of EA,respectively.Analysis of DA,NA,and EA may reflect the fluctuational degrees of VD-BPSD,can provide a useful assessment of VD-BPSD accompanied by clinical scores for VD.展开更多
The authors’meticulous study design is praiseworthy.This randomized,double-blind,controlled trial assessed the efficacy of a vitamin D3 nanoemulsion in comparison to commercially available vitamin D3 formulations.The...The authors’meticulous study design is praiseworthy.This randomized,double-blind,controlled trial assessed the efficacy of a vitamin D3 nanoemulsion in comparison to commercially available vitamin D3 formulations.The study utilized validated assessment instruments,such as the Childhood Autism Rating Scale(CARS),Vineland Adaptive Behavior Scale,and Preschool Language Scale,to ensure an objective evaluation.The findings provide compelling evidence for the superior efficacy of the nanoemulsion.Participants in the nanoemulsion group exhibited significant increases in 25(OH)D3 and 1,25(OH)_(2)D3 levels,along with a reduction in ASD severity and improvements in core symptoms,including social interaction,language,and adaptive behavior.These findings underscore the potential of nanocarriers to address the limitations associated with conventional vitamin D3 supplements,particularly for populations experiencing absorption challenges due to gastrointestinal dysfunction and sensory processing abnormalities,where the oral bioavailability of traditional vitamin D3 formulations is below 50%.Prior research investigating the effects of vitamin D3 on ASD has produced inconsistent outcomes,frequently lacking evidence of significant improvements in core symptoms.This study establishes a connection between improved vitamin D3 bioavailability and observable behavioral enhancements,thereby bridging a crucial gap in translational research.展开更多
文摘cases of postherpetic neuralgia were treated with arranged electro acupuncture and 30 cases with medicine as control. All cases were HIV carriers. The 6 point behavioral rating scale (BRS 6) was used to observe the effect before and after treatment. The results indicate arranged electro acupuncture can cure or reduce the severe pain of postherpetic neuralgia of HIV carriers and the effect was better than medicine.
基金This study was sponsored by the Shanghai Pujiang Program of the Science and Technology Commission of Shanghai Municipality(09PJ1409300)the Three-Year Developmental Plan Project for Traditional Chinese Medicine(major research)of the Shanghai Municipal Health Bureau(ZYSNXD-CCZDYJ028).
文摘To quantitatively evaluate severity of behavioral and psychological symptoms of dementia(BPSD)for vascular dementia(VD).Changes of 51 patients with VD in BPSD between the first and 24th week were assessed using the Neuropsychiatric Inventory(NPI)and the behavioral pathology in Alzheimer’s disease(BEHAVE-AD)rating scale,in detrended fluctuation analysis(DFA)represented by diurnal activity(DA),evening activity(EA),and nocturnal activity(NA),and the relationships were analyzed.The subscores of activity disturbances,diurnal rhythm disturbances,and anxieties and phobias in the BEHAVE-AD score,and that of agitation,irritability,and sleep disorder in the NPI score were significantly increased compared with the first week,as was for the changes for EA in the DFA value.A linear correlation was observed between the changes of activity disturbances plus anxieties and phobias,and those of DA,and between the development of diurnal rhythm and those of EA,the vehement and autism scores and those of DA,and the difference in sleep disorder scores and those of EA,respectively.Analysis of DA,NA,and EA may reflect the fluctuational degrees of VD-BPSD,can provide a useful assessment of VD-BPSD accompanied by clinical scores for VD.
文摘The authors’meticulous study design is praiseworthy.This randomized,double-blind,controlled trial assessed the efficacy of a vitamin D3 nanoemulsion in comparison to commercially available vitamin D3 formulations.The study utilized validated assessment instruments,such as the Childhood Autism Rating Scale(CARS),Vineland Adaptive Behavior Scale,and Preschool Language Scale,to ensure an objective evaluation.The findings provide compelling evidence for the superior efficacy of the nanoemulsion.Participants in the nanoemulsion group exhibited significant increases in 25(OH)D3 and 1,25(OH)_(2)D3 levels,along with a reduction in ASD severity and improvements in core symptoms,including social interaction,language,and adaptive behavior.These findings underscore the potential of nanocarriers to address the limitations associated with conventional vitamin D3 supplements,particularly for populations experiencing absorption challenges due to gastrointestinal dysfunction and sensory processing abnormalities,where the oral bioavailability of traditional vitamin D3 formulations is below 50%.Prior research investigating the effects of vitamin D3 on ASD has produced inconsistent outcomes,frequently lacking evidence of significant improvements in core symptoms.This study establishes a connection between improved vitamin D3 bioavailability and observable behavioral enhancements,thereby bridging a crucial gap in translational research.
