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Barbara Longhi of Ravenna:A Devotional Self-Portrait 被引量:2
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作者 Liana De Girolami Cheney 《Journal of Literature and Art Studies》 2022年第1期17-37,共21页
From the variety of types of portraiture,there evolved the imaging of a self-portrait as we see in Saint Catherine of Alexandria by Barbara Longhi of Ravenna(1552-1638).The self-portrait is a unique work of art,an int... From the variety of types of portraiture,there evolved the imaging of a self-portrait as we see in Saint Catherine of Alexandria by Barbara Longhi of Ravenna(1552-1638).The self-portrait is a unique work of art,an intimate record of a sitter’s personality.It is an acknowledgment of worth,an exercise in technique,and a designator of era,style,and likeness.The self-portrait can be a study in expression,an impersonation of a virtue,or a document in a history of aging.As William Shakespeare noted in Hamlet,“[The self-portrait is]to show virtue her own feature,scorn her own image,and the very age and body of the time his form and pressure.”In the sixteenth-century in Italy,artists often included themselves or their self-portraits in religious and secular scenes as a type of signature,as seen in the paintings of the Longhi family.In their many depictions of Saint Catherine of Alexandria,the Longhis composed two types of such images:a single-solo-image of the saint;and also her presence in a group with saints-a theme known as holy conversation.In her paintings,Barbara Longhi preferred to depict the solo image of Saint Catherine of Alexandria,using herself as a model for the figure of the saint or as a muse impersonating or personifying the saint’s virgo virtue.This essay is composed of two parts:(1)a brief explanation of the meaning of self-portraits in sixteenth-century Italy;and(2)a study of Barbara Longhi’s self-portraits as Saint Catherine of Alexandria. 展开更多
关键词 barbara Longhi Ravenna Saint Catherine of Alexandria SELF-PORTRAIT PERSONIFICATION mirror virgo Christian symbolism MANNERISM Tridentine Reform
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Barbara Longhi’s Saint Agnes of Rome:Iconic Images of Purity and Virtue 被引量:1
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作者 Liana De Girolami Cheney 《Cultural and Religious Studies》 2022年第3期115-136,共22页
Barbara Longhi of Ravenna(1552-1638)enjoyed creating small devotional paintings depicting holy saints,in particular Saint Agnes(c.291-304).This saint’s life and martyrdom was recorded by the Bishop of Milan,Saint Amb... Barbara Longhi of Ravenna(1552-1638)enjoyed creating small devotional paintings depicting holy saints,in particular Saint Agnes(c.291-304).This saint’s life and martyrdom was recorded by the Bishop of Milan,Saint Ambrose(339-397),a Doctor of the Church and theologian,in his book Concerning Virgins(374)and by Jacobus de Voragine,the Archbishop of Genoa,in his Golden Legend(Legenda Aurea,1275).The saint’s story continues to be imaged and recounted to the present day because she is an icon of a pure and virtuous adolescent female.Barbara Longhi,along with her father,Luca Longhi(1507-1580),painted several versions of Saint Agnes.In their many depictions they composed two types of images:a single-solo-image of the saint;and her presence in a group of saints-a theme known as holy conversation.In her paintings of Saint Agnes,however,Barbara Longhi preferred to depict the solo image of the saint as virgo,a young maiden of virtue.This essay is composed of two parts:(1)an account of the life and martyrdom of Saint Agnes;and(2)an iconographical interpretation of Barbara Longhi’s Saint Agnes of Rome. 展开更多
关键词 barbara and Luca Longhi Saint Agnes virgo Christian symbolism MANNERISM Counter-Reformation Movement Pre-Raphaelite Movement
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NEWCONE AND SEED PESTS COLLECTED IN NORTHEASTERN CHINA BARBARA FULGENS KUZNETSOV (LEPIDOPTERA:TORTRICIDAE) THE LUSTROUS SPRUCE CONE MOTH
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作者 孙江华 方三阳 +1 位作者 张旭东 张学克 《Journal of Northeast Forestry University》 SCIE CAS CSCD 1994年第1期28-33,共6页
This paper is the first of a series dealing with morphological characteristics,biological cycle and damage importance of insect species newly identified as cone and seed pests in Northeastern China. The spruce cone mo... This paper is the first of a series dealing with morphological characteristics,biological cycle and damage importance of insect species newly identified as cone and seed pests in Northeastern China. The spruce cone moth Barbara fulgens appears to be a serious pest of korean spruce cones in Heilongiiang province. 展开更多
关键词 CONE Seed barbara fulgens Cone moth
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Generating a 3D Tool to Represent Graphically the Damages of Santa Barbara Castle (Alicante)
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作者 Victor Echarri A. B. Gonzalez Aviles J. Garabito M. I. Perez Millan A. Priego 《Journal of Civil Engineering and Architecture》 2012年第2期197-203,共7页
Santa Barbara castle is one of the largest fortified complexes of the Spanish Mediterranean coast. Set in a strategic enclave in the city of Alicante. It has been transformed over the centuries since its origin, so th... Santa Barbara castle is one of the largest fortified complexes of the Spanish Mediterranean coast. Set in a strategic enclave in the city of Alicante. It has been transformed over the centuries since its origin, so that nowadays includes numerous buildings inside its area. The fortified area contains several lines bastioned and some medieval and Muslim fronts, composed of quadrangular towers. During the years 2007 and 2008, a research team composed of members from the University of Alicante, the University of Burgos and the Polytechnic University of Catalonia has developed a study on the conservation status of the Castle. This study has been funded through research grants from thc Genemlitat Valenciana (Project GV reference 2007/150), and an agreement with Manuel PeIAez Foundation. We have generated a 3D object of the whole, composed by clouds of millions points, through laser-scanner in order to manage the analysis of the architectural element's conservation status that make up the huge fortified complex. This tool reduced greatly the architectural survey work, providing an extremely accurate. They were developed through the program Pointools View, generating JPEG files, which were imported from Autocad. Later we undertook a comprehensive making of photos -- some 7,000 photographs, which we linked to the 3D object. Thus we have immediate access to the photographs of each element of the Castle from the program Pointools View with a simple click on each 3D element. The graphic representation of damages was done on screen with programs Pointools View and Autocad open simultaneously. This technique has meant better accuracy in the study of conservation status and has greatly reduced the time commitment. 展开更多
关键词 Laser-scanner Santa barbara Castle graphic representation of damages Heritage Management.
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生活在他处——Barbara、Claire、Erika作品选录
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《苏州工艺美术职业技术学院学报》 2006年第1期73-78,共6页
Barbara、Claire、Erika是先后来苏州工艺美术职业技术学院进修的三位法国留学生。她们有不一样的身份背景,不一样的性情习惯,所以,她们选择用不一样的方式来表达在中国的生活、情感以及与艺术相关的思考。泼墨于山水,自有闲雅之致;绘... Barbara、Claire、Erika是先后来苏州工艺美术职业技术学院进修的三位法国留学生。她们有不一样的身份背景,不一样的性情习惯,所以,她们选择用不一样的方式来表达在中国的生活、情感以及与艺术相关的思考。泼墨于山水,自有闲雅之致;绘彩于自然,难得亲近之怀。感叹于她们的自由任性,歆羡于她们的轻灵生动。看着她们,就会想到:生活在他处,这是艺术的一种期望。 展开更多
关键词 身份背景 苏州工艺美术职业技术学院 barbara Claire Erika
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Barbara Longhi’s Saint Justina of Padua:Pagan Symbolism and Christian Martyrology
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作者 Liana De Girolami Cheney 《Cultural and Religious Studies》 2022年第9期463-499,共37页
Barbara Longhi of Ravenna(1552-1638)skillfully created small devotional altarpieces depicting holy saints with their respective attributes of martyrdom,seen in Saint Agnes of Rome(c.291-304)with an ewe,Saint Cecilia(c... Barbara Longhi of Ravenna(1552-1638)skillfully created small devotional altarpieces depicting holy saints with their respective attributes of martyrdom,seen in Saint Agnes of Rome(c.291-304)with an ewe,Saint Cecilia(c.200-235)with a portable organ,Saint Catherine of Alexandria(c.287-304)with a broken spiked wheel,and Saint Justina of Padua(c.3rd century)with a small sword in her chest.For their physical sacrifice,Heaven rewarded them with a palm frond as an honorific spiritual gift.Barbara included some of these saints in her paintings on the theme of holy conversation(sacra conversazione;a religious gathering with the Madonna and Child)and depicted the female saints as a single panel-solo image-for private devotion or supplicatory assistance.Most of the biographies and historicity about the lives of these saints are recounted by Jacobus de Voragine(1222-1298),Archbishop of Genoa,in his Golden Legend(Legenda Aurea,1275).This essay only comments on the iconography of one of Barbara’s female saints,Saint Justina of Padua. 展开更多
关键词 barbara and Luca Longhi palm frond MARTYRDOM Saint Justina of Padua Christian iconography pagan symbolism
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The Enlightenment Brought by Undershaft in Major Barbara
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作者 施燕霞 《海外英语》 2019年第2期200-201,共2页
In Bernard Shaw’s play Major Barbara,the arm dealer,Barbara’s father Undershaft is usually considered a totally evil character.In this paper,it is argued that Undershaft is a character of the greatest importance.Tho... In Bernard Shaw’s play Major Barbara,the arm dealer,Barbara’s father Undershaft is usually considered a totally evil character.In this paper,it is argued that Undershaft is a character of the greatest importance.Though hardly the spokesman of the author Bernard Shaw,this sophisticate does represent Bernard to some extent,making the immature protagonist Barbara more aware of the complex reality.His emergence leads to a full understanding of the relation between good and evil,the necessity to eradicate poverty,and the unity of great people of foresight to save the mass. 展开更多
关键词 Bernard Shaw Undershaft ENLIGHTENMENT barbara
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Post Impact of Hydrocarbon Spillage on Physicochemical Parameters and Heavy Metals in the Santa Barbara River, Nembe, Bayelsa State
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作者 Amararu Onyema Isukul Godwin Jeremiah Udom Richmond Uwanemesor Ideozu 《International Journal of Geosciences》 2023年第10期935-954,共20页
The work of the paper focused on the post impact of oil spill contamination of groundwater in Bassambiri Nembe Bayelsa State. Groundwater samples were sampled from hand dug wells from eight stations including the cont... The work of the paper focused on the post impact of oil spill contamination of groundwater in Bassambiri Nembe Bayelsa State. Groundwater samples were sampled from hand dug wells from eight stations including the control point for physico-chemical investigation using sterilized glass bottles. Sampling was carried out upstream and downstream on the Santa Barbara River across the stations and the results are as follows surface water pH ranged 6.90 - 7.50, electrical conductivity 19739.41 μS/cm - 28920.64 μS/cm and Chloride 6019.63 - 9274.82 mg/l. The Total Dissolved Solids (TDS) varied from 10472.72 mg/l - 16538.19 mg/l dissolved oxygen (DO) 6.21 mg/l - 7.371 mg/l while the mean biochemical oxygen demand (BOD) 0.09 ± 0.52 mg/l - 2.4 ± 0.81 mg/l, temperature 28.04℃ - 31.79℃ while total alkalinity is 43.95 mg/L -73.87 mg/L. Calcium ion ranged 375.68 mg/l - 536.72 mg/l, Magnesium ion 88.35 - 243.24 mg/l and Potassium ion 41.27 - 121.17 mg/l. The results of the study showed that the pH, salinity, alkalinity, total suspended solids (TSS), Chlorides, Phosphates, and Nitrates are within permissible limits of the WHO, however the electrical conductivity, TDS, turbidity, DO, BOD, and hardness exceeded WHO permissible limits for drinking water. Total Petroleum Hydrocarbon (TPH) and Heavy metals had low concentrations in the Santa Barbara River across the study area suggesting that surface water is not polluted. However, the surfactants used initially to contain the oil pollution were effective based on this research. 展开更多
关键词 Post Impact Oil Spillage Physiochemical Parameters Santa barbara
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Santa Barbara音效设计加速型工作室
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作者 Digidesign 《世界专业音响与灯光》 2006年第4期63-65,共3页
Santa Barbara音效设计工作室 Santa Barbara音效设计工作室的所有者、著名制作人和作曲家Dominic Camardella正快速行进在未来的创作道路上。
关键词 设计工作室 音效 加速 制作人 SANTA barbara
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Spatiotemporal distribution characteristics of clear-sky downward surface shortwave radiation in Xinjiang
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作者 HUANG Guan CHEN Yonghang +4 位作者 WANG Pengtao FAN Ting HE Qing SHAO Weiling SUN Linlin 《Journal of Arid Land》 2025年第6期772-790,共19页
Given that Xinjiang Uygur Autonomous Region of China possesses exceptionally abundant solar radiation resources that can be harnessed to develop clean energy,accurately characterizing their spatiotemporal distribution... Given that Xinjiang Uygur Autonomous Region of China possesses exceptionally abundant solar radiation resources that can be harnessed to develop clean energy,accurately characterizing their spatiotemporal distribution is crucial.This study investigated the applicability of the Clouds and the Earth's Radiant Energy System(CERES)Single Scanner Footprint TOA/Surface Fluxes and Clouds(SSF)product downward surface shortwave radiation dataset(DSSRCER)under clear-sky conditions in Xinjiang.By integrating multi-source data and utilizing techniques like multivariate fitting and model simulation,we established a two-layer aerosol model and developed a clear-sky downward surface shortwave radiation(DSSR)retrieval model specific to Xinjiang using the Santa Barbara Discrete Atmospheric Radiative Transfer(SBDART)model.We further explored the spatiotemporal distribution characteristics of DSSR under clear-sky conditions in Xinjiang from 2017 to 2019 based on the localized DSSR retrieval model.Our findings revealed a significant discrepancy in DSSRCER under clear-sky conditions at the Xiaotang station in Xinjiang.By comparing,screening,and correcting core input parameters while incorporating the two-layer aerosol model,we achieved a more accurate SBDART simulated DSSR(DSSRSBD)compared to DSSRCER.The annual mean DSSR exhibited a distinct distribution pattern with high values in mountainous regions such as the Altay Mountains,Kunlun Mountains,and Tianshan Mountains and significantly lower values in adjacent lowland areas,including the Tarim River Basin and Junggar Basin.In the four typical administrative regions in northern Xinjiang,the annual mean DSSR(ranging from 551.60 to 586.09 W/m^(2))was lower than that in the five typical administrative regions in southern Xinjiang(ranging from 522.10 to 623.62 W/m^(2)).These spatial variations stem from a complex interplay of factors,including latitude,altitude,solar altitude angle,and sunshine duration.The variations in seasonal average DSSR aligned closely with variations in the solar altitude angle,with summer(774.76 W/m^(2))exhibiting the highest values,followed by spring(684.86 W/m^(2)),autumn(544.76 W/m^(2)),and winter(422.74 W/m^(2)).The monthly average DSSR showed a unimodal distribution,peaking in June(792.94 W/m^(2))and reaching its lowest level in December(363.06 W/m^(2)).Overall,our study findings enhance the current understanding of the spatiotemporal distribution characteristics of DSSR in Xinjiang and provide certain references for the management of clean energy development in this region. 展开更多
关键词 downward surface shortwave radiation(DSSR) clear-sky condition two-layer aerosol model Santa barbara Discrete Atmospheric Radiative Transfer(SBDART) Clouds and the Earth's Radiant Energy System(CERES)
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University of California Santa Barbara 2007 Global Medicine Conference——Integrating Chinese and Western Medicine:The View from China 被引量:1
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作者 夏亦嗣 《Chinese Journal of Integrative Medicine》 SCIE CAS 2007年第3期233-234,共2页
From May 3 through May 6, 2007, the University of California, Santa Barbara (UCSB)'s Global Medicine Project, and Santa Barbara Cottage Hospital cosponsored a conference entitled, “Integrating Chinese and Western ... From May 3 through May 6, 2007, the University of California, Santa Barbara (UCSB)'s Global Medicine Project, and Santa Barbara Cottage Hospital cosponsored a conference entitled, “Integrating Chinese and Western Medicine: The View from China”. A select group of the most prominent doctors in China accepted an invitation to visit UCSB to share their research, case studies, and specific treatment protocols that successfully combine Western medicine and ancient Chinese healing practices to alleviate the suffering caused by some of the most difficult diseases confronting humanity. In China, this type of treatment has been used effectively for more than four decades, and was presented by a group of doctors and research scholars who are the central figures in the evolution of this important paradigm for healing in the 21st Century. 展开更多
关键词 Integrating Chinese and Western Medicine University of California Santa barbara 2007 Global Medicine Conference
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The President of the California Institute of Technology and the Chancellor of the University of California at Santa Barbara Visit Tsinghua
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《Tsinghua Science and Technology》 SCIE EI CAS 2009年第6期731-731,共1页
The President of the Califomia Institute of Technology Professor Jean-Lou Chameau and the Chancellor of the University of California at Santa Barbara Professor Henry Yang both delivered speeches in the Tsinghua Global... The President of the Califomia Institute of Technology Professor Jean-Lou Chameau and the Chancellor of the University of California at Santa Barbara Professor Henry Yang both delivered speeches in the Tsinghua Global Vision Lecture Series during their Tsinghua University visit on August 25, 2009. 展开更多
关键词 Vision The President of the California Institute of Technology and the Chancellor of the University of California at Santa barbara Visit Tsinghua
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President of the California Institute of Technology and Chancellor of the University of California at Santa Barbara Visit Tsinghua University
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《Tsinghua Science and Technology》 SCIE EI CAS 2009年第5期600-600,共1页
The President of the California Institute of Technology Professor Jean-Lou Chameau and the Chancellor of the University of California at Santa Barbara Professor Henry Yang both delivered speeches in the Tsinghua Globa... The President of the California Institute of Technology Professor Jean-Lou Chameau and the Chancellor of the University of California at Santa Barbara Professor Henry Yang both delivered speeches in the Tsinghua Global Vision Lecture Series during their Tsinghua University visit on August 25, 2009. Tsinghua University President Gu Binglin welcomed Professor Chameau and Professor Yang and outlined for them the latest developments at Tsinghua University. The three university presidents expressed the hope that more cooperation in the future could be built between their universities. They discussed collaboration in research and student exchange during their talks. 展开更多
关键词 President of the California Institute of Technology and Chancellor of the University of California at Santa barbara Visit Tsinghua University
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Second President of Austrian National Council Mag. Barbara Prammer Visits China
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作者 Yin Shenglun 《Voice of Friendship》 2004年第6期2-4,共3页
At the invitation of the CPAFFC, a high-ranking delegation of the Austrian Association for Promotion of Friendship and Cultural Relations with China (AAPFCRC) led by Ms. Mag. Barbara Prammer, second president of the Aus-
关键词 INVITATION DELEGATION barbara ranking visited PRES
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告诉你“正在流行”什么 访WGSN创意总监Barbara Kennington女士
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作者 乐怡 《国际服装动态》 2007年第1期30-31,共2页
在万豪酒店里,见到Barbara女士,齐耳的金色短发,黑色真丝衫配牛仔裤,精练能干的女强人造型。她就是现任WGSN创意总监,世界著名的时装设计顾问,其以敏锐的潮流触觉而享誉全球时尚界。八十年代早期,作为伦敦前卫时尚新浪潮的中坚力量,她... 在万豪酒店里,见到Barbara女士,齐耳的金色短发,黑色真丝衫配牛仔裤,精练能干的女强人造型。她就是现任WGSN创意总监,世界著名的时装设计顾问,其以敏锐的潮流触觉而享誉全球时尚界。八十年代早期,作为伦敦前卫时尚新浪潮的中坚力量,她创建了自己的时尚设计品牌,随后又投身时装设计资讯领域,并先后就职于The Bureau、Desmond & Sons、Coats Viyella,这些都是英国百货巨头Marks & Spencer的供应商。之后,便毅然加盟当时还处于新生时期的WGSN公司,为实践全新的资讯服务理念、推动WGSN成为业界领先潮流资讯做出了巨大的贡献。而今,她带着WGSN最新的研究成果——“正在流行”(close-to-season)资讯板块,走入中国时尚界的视野中。 展开更多
关键词 创意总监 WGSN barbara 时尚界 时装设计 万豪酒店 SPENCER 前卫时尚 八十年代
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“不存在的地基”——生态视阈下《无所庇护》中的美国中产阶级问题解析
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作者 谷惠文 陈彦旭 《外语与外语教学》 CSSCI 北大核心 2024年第3期135-144,150,共11页
美国当代女作家芭芭拉·金索沃在小说《无所庇护》中表现出对美国当代社会不平等问题与政治动荡的密切关注,以及对中产阶级生存境遇的深刻忧虑。金索沃通过对比19世纪与21世纪美国两个中产阶级家庭窘迫的生存境遇,对“美国梦”一以... 美国当代女作家芭芭拉·金索沃在小说《无所庇护》中表现出对美国当代社会不平等问题与政治动荡的密切关注,以及对中产阶级生存境遇的深刻忧虑。金索沃通过对比19世纪与21世纪美国两个中产阶级家庭窘迫的生存境遇,对“美国梦”一以贯之的虚伪性作出了批判。在《无所庇护》中,小说中的地名、主人公身份、情节隐喻都与“生态”这一概念密切相关,暗示了作家将生态思想融入对社会和文化批判之中的做法。本文借用了生态系统、食物链、捕食者、生态平衡等多个生态学中的核心理念,对小说中不同时代的中产阶级危机根源进行分析,揭示了文学作为“社会现实矛盾之想象性解决”这一理念所能提供的潜在能动性及其局限性。 展开更多
关键词 芭芭拉·金索沃 《无所庇护》 美国中产阶级 生态视阈
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专访英国新任驻华大使吴百纳:英国不仅要加入亚投行 对丝路基金也很感兴趣
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作者 张璐晶 《中国经济周刊》 2015年第11期50-52,共3页
自1972年中英建交以来,英国驻华大使中首次出现了女性面孔。3月18日,新任英国驻华大使吴百纳(Barbara Janet Woodward)在英国驻华大使官邸举行了上任后的首次记者会。 对吴百纳来说,这是她第二次来中国任职。她曾在2003年到2009年在... 自1972年中英建交以来,英国驻华大使中首次出现了女性面孔。3月18日,新任英国驻华大使吴百纳(Barbara Janet Woodward)在英国驻华大使官邸举行了上任后的首次记者会。 对吴百纳来说,这是她第二次来中国任职。她曾在2003年到2009年在北京英国大使馆任政务参赞。但其实她和中国的缘分早在上世纪80年代就开始,她第一次来中国是在1986年,先后在武汉和南开大学教英语。而她的中文名字"吴百纳",取自"海纳百川"之意,是她在伦敦的中文老师给她取的。 展开更多
关键词 驻华大使 Woodward 中文名字 JANET barbara 经济发展 创始成员 飓风袭击 中英关系 发展阶段
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留美高分学生为什么被劝退?
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作者 薛涌 《留学》 2014年第2期95-96,共2页
留美潮汹涌澎湃了许多年。在这一持续的大潮中,有一股让人们普遍忽视的潜流,那就是高分被劝退的现象。高分劝退高发区:前五十大学所谓高分被劝退,指的是那些托福考到95-100左右,SAT在1900-2000上下的水平。这种学生被美国前五十左右的... 留美潮汹涌澎湃了许多年。在这一持续的大潮中,有一股让人们普遍忽视的潜流,那就是高分被劝退的现象。高分劝退高发区:前五十大学所谓高分被劝退,指的是那些托福考到95-100左右,SAT在1900-2000上下的水平。这种学生被美国前五十左右的大学录取,但读了一年后因跟不上课而被劝退。举个简单的例子:在2013年《美国新闻与世界报道》排名上,有六所大学并列第41。根据2012年录取数据,其中的波士顿大学录取新生的SAT成绩大致在1780-2050之间,加州大学圣巴巴拉分校(UC Santa Barbara)则在1640-1990之间。如果我们把横杆稍微降低一点,以"前八十"强校为基准,那么排在第68的普渡大学,SAT大致在1570-1920之间,排在73位的密西根州立大学则在1430-1840之间。 展开更多
关键词 密西根州立大学 普渡大学 巴巴拉 波士顿大学 SANTA “高分低能” barbara 不知道 七八
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半枝莲提取物对H22荷瘤小鼠免疫功能的影响及其抑瘤作用 被引量:18
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作者 代志军 刘小旭 +5 位作者 汤薇 薛茜 王西京 纪宗正 康华峰 刁岩 《南方医科大学学报》 CAS CSCD 北大核心 2008年第10期1835-1837,共3页
目的探讨中药半枝莲提取物(ESB)的抗肝癌作用及对荷瘤小鼠免疫功能的影响。方法将接种H22肝癌细胞的小鼠分为模型组、ESB高、中、低剂量组(12、6、3g/kg)、5-氟尿嘧啶组(5-Fu组),另设正常对照组,连续给药10d。观察小鼠瘤重、体质量、胸... 目的探讨中药半枝莲提取物(ESB)的抗肝癌作用及对荷瘤小鼠免疫功能的影响。方法将接种H22肝癌细胞的小鼠分为模型组、ESB高、中、低剂量组(12、6、3g/kg)、5-氟尿嘧啶组(5-Fu组),另设正常对照组,连续给药10d。观察小鼠瘤重、体质量、胸腺指数和脾指数;并检测各组淋巴细胞增殖活性、NK细胞活性及脾细胞IL-2分泌量。结果ESB中、高剂量可明显抑制荷瘤小鼠移植瘤的生长,抑瘤率分别为28.68%、36.98%,而且能明显增加小鼠胸腺指数和脾指数(P<0.01),而5-Fu组胸腺指数和脾指数明显降低。模型组荷瘤小鼠脾淋巴细胞增殖活性、NK细胞活性及分泌IL-2能力均明显低于正常对照组(P<0.05)。与模型组比较,5-Fu组荷瘤小鼠的NK细胞活性和脾细胞IL-2分泌量进一步降低(P<0.05)。而ESB高剂量组三者均得到明显改善。ESB中剂量治疗使荷瘤小鼠的NK细胞活性增强,与模型组比较差异显著(P<0.05)。结论ESB可明显抑制H22移植瘤的生长,改善荷瘤小鼠的免疫功能。 展开更多
关键词 半枝莲 肝癌 免疫功能 小鼠
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半枝莲抑制人肝癌QGY-7701细胞增殖研究 被引量:38
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作者 林敬明 刘煜 罗荣城 《南方医科大学学报》 CAS CSCD 北大核心 2006年第5期591-593,共3页
目的探讨半枝莲抑制人肝癌QGY-7701细胞的初步机制。方法MTT法检测半枝莲作用后QGY-7701细胞增殖的改变,光、电镜观察其形态变化,流式细胞仪检测其凋亡细胞比例、细胞周期的变化及凋亡相关基因Bcl-2、Bax、Fas表达。结果半枝莲能抑制QGY... 目的探讨半枝莲抑制人肝癌QGY-7701细胞的初步机制。方法MTT法检测半枝莲作用后QGY-7701细胞增殖的改变,光、电镜观察其形态变化,流式细胞仪检测其凋亡细胞比例、细胞周期的变化及凋亡相关基因Bcl-2、Bax、Fas表达。结果半枝莲能抑制QGY-7701细胞的增殖,作用72h后,细胞呈现凋亡早期形态;凋亡细胞增多;G0/G1期细胞减少,G2/M期细胞增多;Bax表达增强,Bcl-2表达减少,Fas表达变化不明显。结论半枝莲可抑制QGY-7701细胞增殖,可能与通过激活Bcl-2基因家族抑癌基因、诱导细胞凋亡、阻滞细胞周期有关。 展开更多
关键词 半枝莲 原发性肝癌 QGY细胞 凋亡
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