Vitiligo is not only a cosmetic problem,but also a social and psychological problem with the prevalence rate between 1–2%and being highest in India.As far as etiopathogenesis of the disease is concerned,out of variou...Vitiligo is not only a cosmetic problem,but also a social and psychological problem with the prevalence rate between 1–2%and being highest in India.As far as etiopathogenesis of the disease is concerned,out of various theories put forward,some accepted hypothesis is the autoimmune destruction of melanocytes,melanocytes adhesion,neurogenic damage,auto-toxicity.Disease is mainly classified in two forms i.e.segmental vitiligo and non-segmental vitiligo.Treatment of this disease is usually cumbersome and time taking,causing significant impact on quality of life.Moreover,modern treatment is only suppressive but not curative.Medicinal plants are the base of many traditional medicine systems throughout the world for thousands of years and continue to provide new remedies to mankind.If used appropriately,they are comparatively more effective,less toxic and easily available at affordable prices.Detailed management consisting of single herbs and compound formulations along with other regimes has been mentioned to treat this disease in the classical Unani literature which is safe and effective.Aim of this paper was to delineate the vitiligo disease and search for evidence in the management of the disease through Unani and herbal medicines.展开更多
This article studies the rupture of the Keur Bara KAIRE dike, located in the commune of Notto Diobasse in the department of Thiès in Senegal. The village is crossed by a stream which collects rainwater from the w...This article studies the rupture of the Keur Bara KAIRE dike, located in the commune of Notto Diobasse in the department of Thiès in Senegal. The village is crossed by a stream which collects rainwater from the west to the east, following a natural slope. The overflow of this stream causes serious flooding, leading to the total cutting of the road and the isolation of the population. These floods had tragic consequences, resulting in two losses of human life. To regulate the water level, prevent flooding, and protect agricultural and urban areas from overflows, the Senegalese authorities initiated the project to build the Keur Bara KAIRE dike in 2004, but unfortunately, the latter gave way in 2017. The geotechnical analysis was carried out on samples taken from various points on the site, revealing that the terrain is mainly composed of fine sand and the embankment is made with clayey sand. Morphometric and hydrological investigations highlight that the watershed of the Keur Bara KAIRE dike covers an area of 3.72 km2, with a projected flow of 54.99 m3/s. The resizing of the dike revealed the following data: a length of 132 meters and a height of 3 meters. The spillway is 52.99 meters long with a reservoir height of 1.22 meters. The bay walls have a thickness of 50 cm and the embankments have a slope of 1/2 upstream and downstream. The stability calculation on the broken dike reveals a sliding safety factor (FSG) of 1.84 which complies with the standard and an overturning safety factor (FSR) of 0.13 which is not verified. The surface of the watershed which is equal to 3.72 km2, also the smallest height of precipitation is equal to 234.9 mm and the largest is 664.4 mm, according to the ORSTOM and CIEH methods for hydraulic calculations.展开更多
目的考察不同灭菌方法对白热斯灭菌效果及其活性成分含量的影响,选择最适宜的灭菌方法。方法分别采用热压灭菌、流通蒸气灭菌、干热灭菌、60Co辐射灭菌4种不同的灭菌方法对白热斯药材粉末进行灭菌处理,采用HPLC测定白热斯中胡椒碱、异...目的考察不同灭菌方法对白热斯灭菌效果及其活性成分含量的影响,选择最适宜的灭菌方法。方法分别采用热压灭菌、流通蒸气灭菌、干热灭菌、60Co辐射灭菌4种不同的灭菌方法对白热斯药材粉末进行灭菌处理,采用HPLC测定白热斯中胡椒碱、异绿原酸A、异绿原酸C、槲皮素4种指标性成分的含量。比较不同灭菌方法对白热斯中4种指标性成分含量及微生物限度的影响。结果 4种灭菌方法所检测的细菌总数、霉菌、酵母菌和大肠埃希菌均符合《中国药典》的要求。60Co辐照灭菌,辐射剂量为4 k Gy时,4种指标性成分总含量高于其他灭菌方法,损失率为1. 21%。结论白热斯灭菌方法选用60Co辐射灭菌技术,工艺简单,干燥时间短,且能有效保留各指标成分。展开更多
文摘Vitiligo is not only a cosmetic problem,but also a social and psychological problem with the prevalence rate between 1–2%and being highest in India.As far as etiopathogenesis of the disease is concerned,out of various theories put forward,some accepted hypothesis is the autoimmune destruction of melanocytes,melanocytes adhesion,neurogenic damage,auto-toxicity.Disease is mainly classified in two forms i.e.segmental vitiligo and non-segmental vitiligo.Treatment of this disease is usually cumbersome and time taking,causing significant impact on quality of life.Moreover,modern treatment is only suppressive but not curative.Medicinal plants are the base of many traditional medicine systems throughout the world for thousands of years and continue to provide new remedies to mankind.If used appropriately,they are comparatively more effective,less toxic and easily available at affordable prices.Detailed management consisting of single herbs and compound formulations along with other regimes has been mentioned to treat this disease in the classical Unani literature which is safe and effective.Aim of this paper was to delineate the vitiligo disease and search for evidence in the management of the disease through Unani and herbal medicines.
文摘This article studies the rupture of the Keur Bara KAIRE dike, located in the commune of Notto Diobasse in the department of Thiès in Senegal. The village is crossed by a stream which collects rainwater from the west to the east, following a natural slope. The overflow of this stream causes serious flooding, leading to the total cutting of the road and the isolation of the population. These floods had tragic consequences, resulting in two losses of human life. To regulate the water level, prevent flooding, and protect agricultural and urban areas from overflows, the Senegalese authorities initiated the project to build the Keur Bara KAIRE dike in 2004, but unfortunately, the latter gave way in 2017. The geotechnical analysis was carried out on samples taken from various points on the site, revealing that the terrain is mainly composed of fine sand and the embankment is made with clayey sand. Morphometric and hydrological investigations highlight that the watershed of the Keur Bara KAIRE dike covers an area of 3.72 km2, with a projected flow of 54.99 m3/s. The resizing of the dike revealed the following data: a length of 132 meters and a height of 3 meters. The spillway is 52.99 meters long with a reservoir height of 1.22 meters. The bay walls have a thickness of 50 cm and the embankments have a slope of 1/2 upstream and downstream. The stability calculation on the broken dike reveals a sliding safety factor (FSG) of 1.84 which complies with the standard and an overturning safety factor (FSR) of 0.13 which is not verified. The surface of the watershed which is equal to 3.72 km2, also the smallest height of precipitation is equal to 234.9 mm and the largest is 664.4 mm, according to the ORSTOM and CIEH methods for hydraulic calculations.
文摘目的考察不同灭菌方法对白热斯灭菌效果及其活性成分含量的影响,选择最适宜的灭菌方法。方法分别采用热压灭菌、流通蒸气灭菌、干热灭菌、60Co辐射灭菌4种不同的灭菌方法对白热斯药材粉末进行灭菌处理,采用HPLC测定白热斯中胡椒碱、异绿原酸A、异绿原酸C、槲皮素4种指标性成分的含量。比较不同灭菌方法对白热斯中4种指标性成分含量及微生物限度的影响。结果 4种灭菌方法所检测的细菌总数、霉菌、酵母菌和大肠埃希菌均符合《中国药典》的要求。60Co辐照灭菌,辐射剂量为4 k Gy时,4种指标性成分总含量高于其他灭菌方法,损失率为1. 21%。结论白热斯灭菌方法选用60Co辐射灭菌技术,工艺简单,干燥时间短,且能有效保留各指标成分。
