Many tumors are unique to the organs from which they arise. Over the last 20 years, however, most tumors that were thought to be primary in soft tissues (derived from the primitive mesenchyme) and thought not to have ...Many tumors are unique to the organs from which they arise. Over the last 20 years, however, most tumors that were thought to be primary in soft tissues (derived from the primitive mesenchyme) and thought not to have counterparts in bone, were found to, in fact, rarely arise as unique lesions from bone. Some examples include synovial sarcoma, rhabdomyosarcoma and leiomyosarcoma, to name but three. We now have begun to see the reverse with lesions that were initially thought to be unique to bone arising in soft tissue. While this has been well reported with osteosarcoma and Ewing's sarcoma, it has never been reported with Bizarre Parosteal Osteochondromatous Proliferation (BPOP), also known as Nora's lesion. This study explores the first reported case of a soft tissue lesion, with clinical, radiological and histopathological characteristics of BPOP.展开更多
Bizarre parosteal osteochondromatous proliferation (BPOP), as defined by Nora and colleagues in 1983 (also called Nora lesion), is a rare lesion. About 160 cases of BPOP have been presented in the literature to date. ...Bizarre parosteal osteochondromatous proliferation (BPOP), as defined by Nora and colleagues in 1983 (also called Nora lesion), is a rare lesion. About 160 cases of BPOP have been presented in the literature to date. The lesion is an exophytic outgrowth from the cortical surface consisting of bone, cartilage and fibrous tissue. These types of lesions have been reported mostly in the hands and feet. Localization at the level of the skull is extremely rare. We report a case of a young man with multiple Nora’s lesions with atypical localization in the skull and mandible.展开更多
文摘Many tumors are unique to the organs from which they arise. Over the last 20 years, however, most tumors that were thought to be primary in soft tissues (derived from the primitive mesenchyme) and thought not to have counterparts in bone, were found to, in fact, rarely arise as unique lesions from bone. Some examples include synovial sarcoma, rhabdomyosarcoma and leiomyosarcoma, to name but three. We now have begun to see the reverse with lesions that were initially thought to be unique to bone arising in soft tissue. While this has been well reported with osteosarcoma and Ewing's sarcoma, it has never been reported with Bizarre Parosteal Osteochondromatous Proliferation (BPOP), also known as Nora's lesion. This study explores the first reported case of a soft tissue lesion, with clinical, radiological and histopathological characteristics of BPOP.
文摘Bizarre parosteal osteochondromatous proliferation (BPOP), as defined by Nora and colleagues in 1983 (also called Nora lesion), is a rare lesion. About 160 cases of BPOP have been presented in the literature to date. The lesion is an exophytic outgrowth from the cortical surface consisting of bone, cartilage and fibrous tissue. These types of lesions have been reported mostly in the hands and feet. Localization at the level of the skull is extremely rare. We report a case of a young man with multiple Nora’s lesions with atypical localization in the skull and mandible.
