This communication looks at the photo-oxidation of polythene and polypropylene plastic bottle tops that are placed on soil in a hot arid environment. The degree of oxidation of the plastic is monitored by FT-IR spectr...This communication looks at the photo-oxidation of polythene and polypropylene plastic bottle tops that are placed on soil in a hot arid environment. The degree of oxidation of the plastic is monitored by FT-IR spectroscopy. It is noted that while different bottle top types photo-oxidize at different rates, all show an appreciable level of oxidation after half a year of exposure to the environment. The oxidation leads to brittleness of the plastic, which leads to fissure formation in bottle tops of little thickness. This leads to fragmentation of the material upon impact, making plastic bottle tops an appreciable source of microplastics.展开更多
BACKGROUND Cancer-induced incomplete bowel obstruction presents numerous clinical cha-llenges,notably pain management and inflammation control.Conventional thera-pies provide limited relief,prompting investigation int...BACKGROUND Cancer-induced incomplete bowel obstruction presents numerous clinical cha-llenges,notably pain management and inflammation control.Conventional thera-pies provide limited relief,prompting investigation into complementary approa-ches.This study compares the efficacy of bottle gourd moxibustion combined with umbilical therapy(BGM-UT)plus standard palliative care vs standard Wes-tern palliative care alone in symptom alleviation and inflammation reduction.AIM To compare the efficacy of BGM-UT plus standard palliative care vs standard pa-lliative care alone in reducing inflammatory cytokine levels,alleviating symp-toms,and improving gastrointestinal recovery in cancer-induced incomplete bowel obstruction.METHODS A retrospective analysis was conducted on 109 patients aged 18-75 years with cancer-induced incomplete bowel obstruction treated at the Foshan Hospital of Traditional Chinese Medicine between October 2023 and September 2024.The participants were categorized into two groups:(1)Regular group receiving stan-dard palliative care;and(2)BGM-UT group receiving additional moxibustion therapy.The inclusion criteria included ongoing opioid use and a Karnofsky per-formance status score below 60.The treatments were evaluated for 3 weeks in terms of opioid consumption,gastrointestinal function recovery,brief pain inven-tory scores,traditional Chinese medicine symptom scores,and inflammatory cytokine levels.RESULTS Initially,the groups were demographically and clinically comparable.Post-treatment,the BGM-UT group showed significant reductions in opioid intake(P=0.027),improved gastrointestinal recovery times,and enhanced pain management as reflected by their lower brief pain inventory scores(P<0.05).Similarly,the improvement in traditional Chinese medicine scores was greater in the BGM-UT group than in the regular group(P<0.05).Inflam-matory markers including interleukin-6,tumor necrosis factor-α,and C-reactive protein decreased significantly in the BGM-UT group,indicating the superior anti-inflammatory effects of this treatment(P<0.05).CONCLUSION The addition of BGM-UT to standard palliative care enhances pain relief,accelerates gastrointestinal recovery,and effectively reduces inflammatory cytokine levels in patients with cancer-induced incomplete bowel obstruction.This combination therapy offers a promising complementary approach to managing this challenging condition.Further prospective studies are warranted to validate these findings and explore underlying mechanisms.展开更多
Peste des Petits ruminants (PPR) is considered as one of the major constraints to the productivity of small ruminants in Sudan. Presently, control measures for PPR are primarily reliant on vaccination using an attenua...Peste des Petits ruminants (PPR) is considered as one of the major constraints to the productivity of small ruminants in Sudan. Presently, control measures for PPR are primarily reliant on vaccination using an attenuated PPR strain Nigeria 75/1 that has been produced in monolayers of Vero cells grown in static flasks. This study investigates the potential for scaling up PPR vaccine production using roller bottle technology, a more advanced method. A live, homologous vaccine against PPR in sheep and goats was successfully produced on a large scale in roller culture bottles, with DMEM supplemented with ten percent fetal bovine serum serving as the growth medium. The cells were infected with a multiplicity of infection of 0.01, and the vaccine was harvested when the cytopathic effect reached 80%. The vaccine was then freeze-dried to preserve its stability. A series of tests were conducted to ensure the safety and quality of the vaccine. Using PCR, the identity of vaccine was confirmed. It was found to be safe in both single and 100-times dose inoculations in sheep, with the produced batches showing a high titre of 6.4 ± 0.11 log10 TCID50/ml. All batches met the criteria of sterility, passing tests for bacteria, fungi, and mycoplasma. Furthermore, the vaccine proved effective in small ruminants, with antibodies persisting for over a year post-vaccination. The residual moisture content remained below 2.5%, and the vaccine successfully passed vacuum testing. Stability tests indicated that the vaccine has a shelf-life of at least one year when stored at temperatures of 2˚C - 8˚C and −20˚C. These results demonstrate the potential for applying roller bottle culture technology to PPR vaccine production, significantly streamlining the existing process and enhancing its efficiency. Further research is warranted to address the economic analyses of adopting roller bottle technology with existing PPR control program.展开更多
Graphene oxide(GO)is a 2D coating material used to improve fiber optics sensors’response to relative humidity.Microbottle resonators(MBRs)have garnered more attention as sensing media structures.An MBR with a 190μm ...Graphene oxide(GO)is a 2D coating material used to improve fiber optics sensors’response to relative humidity.Microbottle resonators(MBRs)have garnered more attention as sensing media structures.An MBR with a 190μm diameter was coated with GO.Then,tapered fiber light coupling was used to investigate the relative humidity sensing performance in the range of 35—70%RH at 25℃.The MBR showed a higher Q factor before and after GO coating.The sensitivity of 0.115 dB/%RH was recorded with the 190μm GO-coated MBR sample compared to a sensitivity of 0.022 dB/%RH for the uncoated MBR sample.These results show that the MBR can be used in fiber optic sensing applications for environmental sensing.展开更多
Polycarbonate plastics containing bisphenol A (BPA) used to manufacture drinking water bottles. Kurdistan region in northern Iraq is a developed area with increased pollution from plastic bottles. Trace amounts of BPA...Polycarbonate plastics containing bisphenol A (BPA) used to manufacture drinking water bottles. Kurdistan region in northern Iraq is a developed area with increased pollution from plastic bottles. Trace amounts of BPA have been detected in bottled water samples. The absorption of BPA was measured with HPLC using a vertical cultivation system with Bulbs of the Allium Cepa plant planted in these plastic bottles with monitored growth. Vertical cultivation was found to have a low level of BPA in the plant cells, making it a safe cultivation method under specific climate conditions. The mean concentration of BPA in vertical cultivation is 0.19 ug/ml (3.8 ng for a 20 uL injection), and the Limit of Quantification (LOQ) is 0.63 ug/ml (12.7 ng for 20 uL injection). While Scanning Electron Microscope (SEM) shows that the concentrations are relatively low in water samples stored at room temperature compared to those exposed to direct sunlight (40°C) and water bottle samples stored at (-4°C), The correlation coefficients were found to be good (0.9992). SEM is used for plastic bottle samples stored at different temperatures. The images identify compound decay and explore the morphology of BPA in manufactured plastic materials.展开更多
THE snuft bottle came toChina from Italy,but once itwas in China, it was turnedinto an exquisite object of art.The Italians say that long,longago a tobacconist stocked a greatdeal of tobacco,but one day hediscovered i...THE snuft bottle came toChina from Italy,but once itwas in China, it was turnedinto an exquisite object of art.The Italians say that long,longago a tobacconist stocked a greatdeal of tobacco,but one day hediscovered it has all gone rotten andwas exuding a special smell。展开更多
The experiment was conducted at the experimental field of Olericulture Division, Horticulture Research Centre (HRC), Bangladesh Agricultural Research Institute (BARI), Gazipur, Bangladesh during the winter season of 2...The experiment was conducted at the experimental field of Olericulture Division, Horticulture Research Centre (HRC), Bangladesh Agricultural Research Institute (BARI), Gazipur, Bangladesh during the winter season of 2018-2019 to study the genetic architecture of yield in a seven parent half diallel cross of bottle gourd. The values of mean square for GCA (general combining ability) and SCA (specific combining ability) were highly significant which suggested the presence of both additive and non-additive genetic variance in the population. But the higher magnitude of GCA compared to SCA indicated predominance of additive genetic variance. In most of the cases, the cross between poor and poor parents showed positive SCA effect for fruit yield, which indicated the higher yield. The estimates of significant positive better parent heterosis ranged from 6.27 to 49.72 percent. Analysis of genetic components of variation suggested that additive components were more important in the inheritance of fruit yield. This character was observed being controlled by two to three pairs of genes or groups of genes. Narrow sense heritability was 23 percent indicating probability of selection in generations. The graphical analysis also indicated wide genetic diversity among the parents.展开更多
The champagne bottle neck(CBN) sign refers to a reduction in the diameter of the proximal portion of the internal carotid artery that resembles a CBN, and is a characteristic feature of Moyamoya disease. A 43-yearold ...The champagne bottle neck(CBN) sign refers to a reduction in the diameter of the proximal portion of the internal carotid artery that resembles a CBN, and is a characteristic feature of Moyamoya disease. A 43-yearold woman with an infarction of the posterior limb of the left internal capsule was diagnosed with Moyamoya syndrome associated with Graves' disease. The CBN sign was observed bilaterally. Cerebral revascularization surgery was performed, including left-sided superficial temporal artery to middle cerebral artery anastomosis. During four years of follow-up, she maintained a euthyroid state and did not have any further cerebral ischemic events. The CBN signs remained unchanged on both sides during this time. This is the first report of the CBN sign in a patient with Moyamoya syndrome associated with Graves' disease.展开更多
The adsorption of Pb(II)on silica gel synthesized from chemical glass bottle waste has been studied.The effect of independent variables(adsorbent dose,initial concentration of Pb(II),contact time,and pH)on the Pb(II)r...The adsorption of Pb(II)on silica gel synthesized from chemical glass bottle waste has been studied.The effect of independent variables(adsorbent dose,initial concentration of Pb(II),contact time,and pH)on the Pb(II)removal from water was evaluated and optimized using the Response Surface Methodology(RSM).Under optimized conditions(adsorbent dose:20 mg;contact time:30 min;initial Pb(II)concentration:120 mg.L^(−1);and pH:8),the removal of Pb(II)was 99.77%.The adsorption equilibrium data obtained from the batch experiment were investigated using different isotherm models.The Langmuir isotherm model fits the experimental data.This shows that the surface of the silica gel synthesized from chemical bottles waste was covered by a Pb(II)monolayer.XRF analysis showed that the synthesized silica gel had a SiO_(2) content of 75.63%.Amorphous silica was observed from XRD analysis.SEM-EDX characterization showed that Pb was adsorbed on the silica gel surface.SEM analysis showed that silica gel has irregular particles with a surface area of 297.08 m2.g^(−1) with a pore radius of 15.74 nm calculated from BET analysis.展开更多
This research focuses on the effective removal of methylene blue dye using silica gel synthesized from chemical glass bottle waste as an environmentally friendly and cost-effective adsorbent.The adsorption process was...This research focuses on the effective removal of methylene blue dye using silica gel synthesized from chemical glass bottle waste as an environmentally friendly and cost-effective adsorbent.The adsorption process was optimized using Box-Behnken Design(BBD)and Response Surface Methodology(RSM)to investigate the influence of pH(6;8 and 10),contact time(15;30 and 45 min),adsorbent mass(30;50 and 70 mg),and initial concentration(20;50 and 80 mg/L)of the adsorbate on the adsorption efficiency.The BBD was conducted using Google Colaboratory software,which encompassed 27 experiments with randomly assigned combinations.The silica gel synthesized from chemical glass bottle was characterized by XRD,FTIR,SEM-EDX and TEM.The adsorption result was measured by spectrophotometer UV-Vis.The optimized conditions resulted in a remarkable methylene blue removal efficiency of 99.41%.Characterization of the silica gel demonstrated amorphous morphology and prominent absorption bands characteristic of silica.The Langmuir isotherm model best described the adsorption behavior,revealing chemisorption with a monolayer coverage of methylene blue on the adsorbent surface,and a maximum adsorption capacity of 82.02 mg/g.Additionally,the pseudo-second-order kinetics model indicated a chemisorption mechanism during the adsorption process.The findings highlight the potential of silica gel from chemical glass bottle waste as a promising adsorbent for wastewater treatment,offering economic and environmental benefits.Further investigations can explore its scalability,regenerability,and reusability for industrial-scale applications.展开更多
The whispering gallery mode(WGM)based micro-bottle resonator(MBR)sensor has been proposed and demonstrated for relative humidity measurement by using an agarose gel as a transducer.MBR was fabricated by using a soften...The whispering gallery mode(WGM)based micro-bottle resonator(MBR)sensor has been proposed and demonstrated for relative humidity measurement by using an agarose gel as a transducer.MBR was fabricated by using a soften-and-compress method to form a 190μm bulge bottle.The micro-bottle was optically excited by a 3μm tapered fiber and it exhibits a resonance with a Q factor in an order of 10^(5).The agarose coated MBR produces a good sensing response towards humidity with the sensitivity of 0.107 d B/%RH and linearity of 99.614%.The agarose hydrophilic nature and its changing porosity and refractive index with increasing relative humidity made the coated MBR structure to be more sensitive than the uncoated structure.This humidity sensor has a simple fabrication and is showing good sensitivity,linearity,resolution,response time and operational in a wide humidity range.展开更多
Assessment of water and energy footprint for eight bottled water industries was carried out. The investigation showed that one litre of bottled water has a water footprint of 17.41 litres and energy footprint of 7.08 ...Assessment of water and energy footprint for eight bottled water industries was carried out. The investigation showed that one litre of bottled water has a water footprint of 17.41 litres and energy footprint of 7.08 MJ. Water consumption by the industry comprises 61% during material production, 17% in processes, 16% in energy and only 6% in the actual product. Hence, maximum consumption of water is in material production, while the processes required a smaller fraction of the total water and energy consumed. Therefore, water footprint can be reduced through optimization of water consumption in material production.展开更多
The pursuit of alternative safe water has increased dramatically the world trade in bottled water. Events happened in Canada which changed the population’s perception about the quality of tap water, despite all gover...The pursuit of alternative safe water has increased dramatically the world trade in bottled water. Events happened in Canada which changed the population’s perception about the quality of tap water, despite all government efforts. Media has an important role to pass on information because there is value judgment in its reports. As a result, this study aims to present recent data from two Canadian newspapers of national circulation, which refer to tap water and bottled water. It used quantitative and qualitative data for this analysis. The study concludes that the media, taken into consideration, provides its readers with important information, but the information can also be ambiguous. Nevertheless, it arouses interest in further research about this subject matter and about protecting water resources.展开更多
BACKGROUND: Bottle gourd(Lagenaria siceraria) is popularly known as lauki, ghia or dudhi in India. Its consumption is advocated by traditional medicine healers for controlling diabetes mellitus, hypertension, liver di...BACKGROUND: Bottle gourd(Lagenaria siceraria) is popularly known as lauki, ghia or dudhi in India. Its consumption is advocated by traditional medicine healers for controlling diabetes mellitus, hypertension, liver diseases, weight loss and other diseases. However, in last few years there have been reports of suspected toxicity due to consumption of its juice leading to severe vomiting and upper gastrointestinal bleeding. As emergency physicians we need to be aware of this very rare poisoning specially in India.METHODS: We present a case of a 52-year-old woman who presented with multiple episodes of hematemesis and shock to the emergency department(ED) after consuming bottle gourd juice. The patient was resuscitated and stabilized with fl uids, proton pump inhibitors and antiemetics and shifted to the intensive care unit(ICU) under the care of a gastroenterology team for urgent endoscopy and further management.RESULTS: The patient received intravenous fluids, antibiotics, antiemetics, and antacids and underwent upper gastroenterologic endoscopy during the hospitalization. She was discharged in a stable condition 4 days later.CONCLUSIONS: As a member of the Cucurbitaceae family, bottle gourd contains toxic tetracyclic triterpenoid compounds called cucurbitacins which are responsible for the bitter taste and toxicity. There is no known antidote for this toxicity, and clinicians treat such patients symptomatically only. It is important to educate the public about the harmful effects of this potentially life-threatening toxicity.展开更多
In this study</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> nineteen different brands of bottled mineral waters (7 brands local a...In this study</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> nineteen different brands of bottled mineral waters (7 brands local and 12 brands imported) were collected from supermarkets and independent food stores throughout Djibouti. The chemical composition mentioned on the labels of the nineteen bottled mineral waters ha</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> made the subject of a first verification by Ionic Balance Error (IBE). It was found out of the nineteen brands selected, 12 brands (2 brands local and 10 brands imported) had acceptable charge balance error. Correlation Analysis (CA), Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) were used to analyze the data collected from the labels of bottled water. The obtained results showed that the 12 brands of studied waters can be grouped in 4 distinct classes with similar chemical characteristics. Two local and one imported brands have the same chemical composition but marketed under different names. It was observed that the chemical content local water brands w</span><span style="font-family:Verdana;">ere</span><span style="font-family:""><span style="font-family:Verdana;"> within the normal range prescribed by both WHO and USEPA except five imported water brands that have concentration values Ca, HCO</span><sub><span style="font-size:12px;font-family:Verdana;">3</span></sub><span style="font-family:Verdana;">, Mg and SO</span><sub><span style="font-size:12px;font-family:Verdana;">4</span></sub><span style="font-family:Verdana;"> beyond acceptable standards. Total hardness values classified most of the studied brands from moderate to very hard water.展开更多
Background Machine learning-based beer bottle-defect detection is a complex technology that runs automatically;however,it consumes considerable memory,is expensive,and poses a certain danger when training novice opera...Background Machine learning-based beer bottle-defect detection is a complex technology that runs automatically;however,it consumes considerable memory,is expensive,and poses a certain danger when training novice operators.Moreover,some topics are difficult to learn from experimental lectures,such as digital image processing and computer vision.However,virtual simulation experiments have been widely used to good effect within education.A virtual simulation of the design and manufacture of a beer bottle-defect detection system will not only help the students to increase their image-processing knowledge,but also improve their ability to solve complex engineering problems and design complex systems.Methods The hardware models for the experiment(camera,light source,conveyor belt,power supply,manipulator,and computer)were built using the 3DS MAX modeling and animation software.The Unreal Engine 4(UE4)game engine was utilized to build a virtual design room,design the interactive operations,and simulate the system operation.Results The results showed that the virtual-simulation system received much better experimental feedback,which facilitated the design and manufacture of a beer bottle-defect detection system.The specialized functions of the functional modules in the detection system,including a basic experimental operation menu,power switch,image shooting,image processing,and manipulator grasping,allowed students(or virtual designers)to easily build a detection system by retrieving basic models from the model library,and creating the beer-bottle transportation,image shooting,image processing,defect detection,and defective-product removal.The virtual simulation experiment was completed with image processing as the main body.Conclusions By mainly focusing on bottle mouth defect detection,the detection system dedicates more attention to the user and the task.With more detailed tasks available,the virtual system will eventually yield much better results as a training tool for image processing education.In addition,a novel visual perception-thinking pedagogical framework enables better comprehension than the traditional lecture-tutorial style.展开更多
Objective:To determine the efficacy of WHO impregnated paper and CDC coated bottle based on number of storage days and number of limes of consecutive use,in the assessment of insecticide vector susceptibility tests in...Objective:To determine the efficacy of WHO impregnated paper and CDC coated bottle based on number of storage days and number of limes of consecutive use,in the assessment of insecticide vector susceptibility tests in laboratory and field conditions.Methods:Larvae and pupae of Anopheles gambiae s.l.mosquitoes were collected from the breeding sites in Seme-Kpodji and Cotonou districts in Southern Benin in April 2013 during the first rainy season.Anopheles gambiae s.l.mosquitoes were also collected from the breeding sites in Parakou district in Northern Benin in May 2013 at the beginning of the rainy season.Susceptibility tests were done using impregnated paper with bendiocarb(0.1%)following WHO protocol and stock solutions of permethrin(21.5 ug per bottle)and deltamethrin(12.5 ug per bottle)following CDC protocol on unfed female mosquitoes aged 2-5 days old.These bioassays were repeated a certain number of times.The temperature and relative humidity were monitored and recorded during the susceptibility tests.Results:This study showed that a WHO impregnated paper with bendiocarb could be used four times during four consecutive days in field conditions.Regarding a Wheaton coated bottle with permethrin or deltamethrin,they could be used at least three limes during four consecutive days in laboratory conditions.Conclusions:The day storage and the number of times that a WHO impregnated paper and a CDC coated bottle maintained their efficacy are useful in the assessment of insecticide vectors susceptibility tests.展开更多
In a previous paper by the author joint with Baogang XU published in Discrete Math in 2018, we show that every non-planar toroidal graph can be edge partitioned into a planar graph and an outerplanar graph. This edge ...In a previous paper by the author joint with Baogang XU published in Discrete Math in 2018, we show that every non-planar toroidal graph can be edge partitioned into a planar graph and an outerplanar graph. This edge partition then implies some results in thickness and outerthickness of toroidal graphs. In particular, if each planar graph has outerthickness at most 2(conjectured by Chartrand, Geller and Hedetniemi in 1971 and the confirmation of the conjecture was announced by Gon?calves in 2005), then the outerthickness of toroidal graphs is at most 3 which is the best possible due to K7.In this paper we continue to study the edge partition for projective planar graphs and Klein bottle embeddable graphs. We show that(1) every non-planar but projective planar graph can be edge partitioned into a planar graph and a union of caterpillar trees;and(2) every non-planar Klein bottle embeddable graph can be edge partitioned into a planar graph and a subgraph of two vertex amalgamation of a caterpillar tree with a cycle with pendant edges. As consequences,the thinkness of projective planar graphs and Klein bottle embeddabe graphs are at most 2,which are the best possible, and the outerthickness of these graphs are at most 3.展开更多
文摘This communication looks at the photo-oxidation of polythene and polypropylene plastic bottle tops that are placed on soil in a hot arid environment. The degree of oxidation of the plastic is monitored by FT-IR spectroscopy. It is noted that while different bottle top types photo-oxidize at different rates, all show an appreciable level of oxidation after half a year of exposure to the environment. The oxidation leads to brittleness of the plastic, which leads to fissure formation in bottle tops of little thickness. This leads to fragmentation of the material upon impact, making plastic bottle tops an appreciable source of microplastics.
基金Supported by Medical Research Project of Foshan Health Bureau in 2024,No.20240243.
文摘BACKGROUND Cancer-induced incomplete bowel obstruction presents numerous clinical cha-llenges,notably pain management and inflammation control.Conventional thera-pies provide limited relief,prompting investigation into complementary approa-ches.This study compares the efficacy of bottle gourd moxibustion combined with umbilical therapy(BGM-UT)plus standard palliative care vs standard Wes-tern palliative care alone in symptom alleviation and inflammation reduction.AIM To compare the efficacy of BGM-UT plus standard palliative care vs standard pa-lliative care alone in reducing inflammatory cytokine levels,alleviating symp-toms,and improving gastrointestinal recovery in cancer-induced incomplete bowel obstruction.METHODS A retrospective analysis was conducted on 109 patients aged 18-75 years with cancer-induced incomplete bowel obstruction treated at the Foshan Hospital of Traditional Chinese Medicine between October 2023 and September 2024.The participants were categorized into two groups:(1)Regular group receiving stan-dard palliative care;and(2)BGM-UT group receiving additional moxibustion therapy.The inclusion criteria included ongoing opioid use and a Karnofsky per-formance status score below 60.The treatments were evaluated for 3 weeks in terms of opioid consumption,gastrointestinal function recovery,brief pain inven-tory scores,traditional Chinese medicine symptom scores,and inflammatory cytokine levels.RESULTS Initially,the groups were demographically and clinically comparable.Post-treatment,the BGM-UT group showed significant reductions in opioid intake(P=0.027),improved gastrointestinal recovery times,and enhanced pain management as reflected by their lower brief pain inventory scores(P<0.05).Similarly,the improvement in traditional Chinese medicine scores was greater in the BGM-UT group than in the regular group(P<0.05).Inflam-matory markers including interleukin-6,tumor necrosis factor-α,and C-reactive protein decreased significantly in the BGM-UT group,indicating the superior anti-inflammatory effects of this treatment(P<0.05).CONCLUSION The addition of BGM-UT to standard palliative care enhances pain relief,accelerates gastrointestinal recovery,and effectively reduces inflammatory cytokine levels in patients with cancer-induced incomplete bowel obstruction.This combination therapy offers a promising complementary approach to managing this challenging condition.Further prospective studies are warranted to validate these findings and explore underlying mechanisms.
文摘Peste des Petits ruminants (PPR) is considered as one of the major constraints to the productivity of small ruminants in Sudan. Presently, control measures for PPR are primarily reliant on vaccination using an attenuated PPR strain Nigeria 75/1 that has been produced in monolayers of Vero cells grown in static flasks. This study investigates the potential for scaling up PPR vaccine production using roller bottle technology, a more advanced method. A live, homologous vaccine against PPR in sheep and goats was successfully produced on a large scale in roller culture bottles, with DMEM supplemented with ten percent fetal bovine serum serving as the growth medium. The cells were infected with a multiplicity of infection of 0.01, and the vaccine was harvested when the cytopathic effect reached 80%. The vaccine was then freeze-dried to preserve its stability. A series of tests were conducted to ensure the safety and quality of the vaccine. Using PCR, the identity of vaccine was confirmed. It was found to be safe in both single and 100-times dose inoculations in sheep, with the produced batches showing a high titre of 6.4 ± 0.11 log10 TCID50/ml. All batches met the criteria of sterility, passing tests for bacteria, fungi, and mycoplasma. Furthermore, the vaccine proved effective in small ruminants, with antibodies persisting for over a year post-vaccination. The residual moisture content remained below 2.5%, and the vaccine successfully passed vacuum testing. Stability tests indicated that the vaccine has a shelf-life of at least one year when stored at temperatures of 2˚C - 8˚C and −20˚C. These results demonstrate the potential for applying roller bottle culture technology to PPR vaccine production, significantly streamlining the existing process and enhancing its efficiency. Further research is warranted to address the economic analyses of adopting roller bottle technology with existing PPR control program.
文摘Graphene oxide(GO)is a 2D coating material used to improve fiber optics sensors’response to relative humidity.Microbottle resonators(MBRs)have garnered more attention as sensing media structures.An MBR with a 190μm diameter was coated with GO.Then,tapered fiber light coupling was used to investigate the relative humidity sensing performance in the range of 35—70%RH at 25℃.The MBR showed a higher Q factor before and after GO coating.The sensitivity of 0.115 dB/%RH was recorded with the 190μm GO-coated MBR sample compared to a sensitivity of 0.022 dB/%RH for the uncoated MBR sample.These results show that the MBR can be used in fiber optic sensing applications for environmental sensing.
文摘Polycarbonate plastics containing bisphenol A (BPA) used to manufacture drinking water bottles. Kurdistan region in northern Iraq is a developed area with increased pollution from plastic bottles. Trace amounts of BPA have been detected in bottled water samples. The absorption of BPA was measured with HPLC using a vertical cultivation system with Bulbs of the Allium Cepa plant planted in these plastic bottles with monitored growth. Vertical cultivation was found to have a low level of BPA in the plant cells, making it a safe cultivation method under specific climate conditions. The mean concentration of BPA in vertical cultivation is 0.19 ug/ml (3.8 ng for a 20 uL injection), and the Limit of Quantification (LOQ) is 0.63 ug/ml (12.7 ng for 20 uL injection). While Scanning Electron Microscope (SEM) shows that the concentrations are relatively low in water samples stored at room temperature compared to those exposed to direct sunlight (40°C) and water bottle samples stored at (-4°C), The correlation coefficients were found to be good (0.9992). SEM is used for plastic bottle samples stored at different temperatures. The images identify compound decay and explore the morphology of BPA in manufactured plastic materials.
文摘THE snuft bottle came toChina from Italy,but once itwas in China, it was turnedinto an exquisite object of art.The Italians say that long,longago a tobacconist stocked a greatdeal of tobacco,but one day hediscovered it has all gone rotten andwas exuding a special smell。
文摘The experiment was conducted at the experimental field of Olericulture Division, Horticulture Research Centre (HRC), Bangladesh Agricultural Research Institute (BARI), Gazipur, Bangladesh during the winter season of 2018-2019 to study the genetic architecture of yield in a seven parent half diallel cross of bottle gourd. The values of mean square for GCA (general combining ability) and SCA (specific combining ability) were highly significant which suggested the presence of both additive and non-additive genetic variance in the population. But the higher magnitude of GCA compared to SCA indicated predominance of additive genetic variance. In most of the cases, the cross between poor and poor parents showed positive SCA effect for fruit yield, which indicated the higher yield. The estimates of significant positive better parent heterosis ranged from 6.27 to 49.72 percent. Analysis of genetic components of variation suggested that additive components were more important in the inheritance of fruit yield. This character was observed being controlled by two to three pairs of genes or groups of genes. Narrow sense heritability was 23 percent indicating probability of selection in generations. The graphical analysis also indicated wide genetic diversity among the parents.
文摘The champagne bottle neck(CBN) sign refers to a reduction in the diameter of the proximal portion of the internal carotid artery that resembles a CBN, and is a characteristic feature of Moyamoya disease. A 43-yearold woman with an infarction of the posterior limb of the left internal capsule was diagnosed with Moyamoya syndrome associated with Graves' disease. The CBN sign was observed bilaterally. Cerebral revascularization surgery was performed, including left-sided superficial temporal artery to middle cerebral artery anastomosis. During four years of follow-up, she maintained a euthyroid state and did not have any further cerebral ischemic events. The CBN signs remained unchanged on both sides during this time. This is the first report of the CBN sign in a patient with Moyamoya syndrome associated with Graves' disease.
文摘The adsorption of Pb(II)on silica gel synthesized from chemical glass bottle waste has been studied.The effect of independent variables(adsorbent dose,initial concentration of Pb(II),contact time,and pH)on the Pb(II)removal from water was evaluated and optimized using the Response Surface Methodology(RSM).Under optimized conditions(adsorbent dose:20 mg;contact time:30 min;initial Pb(II)concentration:120 mg.L^(−1);and pH:8),the removal of Pb(II)was 99.77%.The adsorption equilibrium data obtained from the batch experiment were investigated using different isotherm models.The Langmuir isotherm model fits the experimental data.This shows that the surface of the silica gel synthesized from chemical bottles waste was covered by a Pb(II)monolayer.XRF analysis showed that the synthesized silica gel had a SiO_(2) content of 75.63%.Amorphous silica was observed from XRD analysis.SEM-EDX characterization showed that Pb was adsorbed on the silica gel surface.SEM analysis showed that silica gel has irregular particles with a surface area of 297.08 m2.g^(−1) with a pore radius of 15.74 nm calculated from BET analysis.
基金funded by Directorate of Research and Community Service(DRPM,Direktorat Riset dan Pengabdian Kepada Masyarakat)ITS through the ITS Research Local Grant(No.1727/PKS/ITS/2023).
文摘This research focuses on the effective removal of methylene blue dye using silica gel synthesized from chemical glass bottle waste as an environmentally friendly and cost-effective adsorbent.The adsorption process was optimized using Box-Behnken Design(BBD)and Response Surface Methodology(RSM)to investigate the influence of pH(6;8 and 10),contact time(15;30 and 45 min),adsorbent mass(30;50 and 70 mg),and initial concentration(20;50 and 80 mg/L)of the adsorbate on the adsorption efficiency.The BBD was conducted using Google Colaboratory software,which encompassed 27 experiments with randomly assigned combinations.The silica gel synthesized from chemical glass bottle was characterized by XRD,FTIR,SEM-EDX and TEM.The adsorption result was measured by spectrophotometer UV-Vis.The optimized conditions resulted in a remarkable methylene blue removal efficiency of 99.41%.Characterization of the silica gel demonstrated amorphous morphology and prominent absorption bands characteristic of silica.The Langmuir isotherm model best described the adsorption behavior,revealing chemisorption with a monolayer coverage of methylene blue on the adsorbent surface,and a maximum adsorption capacity of 82.02 mg/g.Additionally,the pseudo-second-order kinetics model indicated a chemisorption mechanism during the adsorption process.The findings highlight the potential of silica gel from chemical glass bottle waste as a promising adsorbent for wastewater treatment,offering economic and environmental benefits.Further investigations can explore its scalability,regenerability,and reusability for industrial-scale applications.
基金the University of Malaya(No.IIRG005C-19IISS)INTI International University(No.INTI-FIT-03-2020)。
文摘The whispering gallery mode(WGM)based micro-bottle resonator(MBR)sensor has been proposed and demonstrated for relative humidity measurement by using an agarose gel as a transducer.MBR was fabricated by using a soften-and-compress method to form a 190μm bulge bottle.The micro-bottle was optically excited by a 3μm tapered fiber and it exhibits a resonance with a Q factor in an order of 10^(5).The agarose coated MBR produces a good sensing response towards humidity with the sensitivity of 0.107 d B/%RH and linearity of 99.614%.The agarose hydrophilic nature and its changing porosity and refractive index with increasing relative humidity made the coated MBR structure to be more sensitive than the uncoated structure.This humidity sensor has a simple fabrication and is showing good sensitivity,linearity,resolution,response time and operational in a wide humidity range.
文摘Assessment of water and energy footprint for eight bottled water industries was carried out. The investigation showed that one litre of bottled water has a water footprint of 17.41 litres and energy footprint of 7.08 MJ. Water consumption by the industry comprises 61% during material production, 17% in processes, 16% in energy and only 6% in the actual product. Hence, maximum consumption of water is in material production, while the processes required a smaller fraction of the total water and energy consumed. Therefore, water footprint can be reduced through optimization of water consumption in material production.
文摘The pursuit of alternative safe water has increased dramatically the world trade in bottled water. Events happened in Canada which changed the population’s perception about the quality of tap water, despite all government efforts. Media has an important role to pass on information because there is value judgment in its reports. As a result, this study aims to present recent data from two Canadian newspapers of national circulation, which refer to tap water and bottled water. It used quantitative and qualitative data for this analysis. The study concludes that the media, taken into consideration, provides its readers with important information, but the information can also be ambiguous. Nevertheless, it arouses interest in further research about this subject matter and about protecting water resources.
文摘BACKGROUND: Bottle gourd(Lagenaria siceraria) is popularly known as lauki, ghia or dudhi in India. Its consumption is advocated by traditional medicine healers for controlling diabetes mellitus, hypertension, liver diseases, weight loss and other diseases. However, in last few years there have been reports of suspected toxicity due to consumption of its juice leading to severe vomiting and upper gastrointestinal bleeding. As emergency physicians we need to be aware of this very rare poisoning specially in India.METHODS: We present a case of a 52-year-old woman who presented with multiple episodes of hematemesis and shock to the emergency department(ED) after consuming bottle gourd juice. The patient was resuscitated and stabilized with fl uids, proton pump inhibitors and antiemetics and shifted to the intensive care unit(ICU) under the care of a gastroenterology team for urgent endoscopy and further management.RESULTS: The patient received intravenous fluids, antibiotics, antiemetics, and antacids and underwent upper gastroenterologic endoscopy during the hospitalization. She was discharged in a stable condition 4 days later.CONCLUSIONS: As a member of the Cucurbitaceae family, bottle gourd contains toxic tetracyclic triterpenoid compounds called cucurbitacins which are responsible for the bitter taste and toxicity. There is no known antidote for this toxicity, and clinicians treat such patients symptomatically only. It is important to educate the public about the harmful effects of this potentially life-threatening toxicity.
文摘In this study</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> nineteen different brands of bottled mineral waters (7 brands local and 12 brands imported) were collected from supermarkets and independent food stores throughout Djibouti. The chemical composition mentioned on the labels of the nineteen bottled mineral waters ha</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> made the subject of a first verification by Ionic Balance Error (IBE). It was found out of the nineteen brands selected, 12 brands (2 brands local and 10 brands imported) had acceptable charge balance error. Correlation Analysis (CA), Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) were used to analyze the data collected from the labels of bottled water. The obtained results showed that the 12 brands of studied waters can be grouped in 4 distinct classes with similar chemical characteristics. Two local and one imported brands have the same chemical composition but marketed under different names. It was observed that the chemical content local water brands w</span><span style="font-family:Verdana;">ere</span><span style="font-family:""><span style="font-family:Verdana;"> within the normal range prescribed by both WHO and USEPA except five imported water brands that have concentration values Ca, HCO</span><sub><span style="font-size:12px;font-family:Verdana;">3</span></sub><span style="font-family:Verdana;">, Mg and SO</span><sub><span style="font-size:12px;font-family:Verdana;">4</span></sub><span style="font-family:Verdana;"> beyond acceptable standards. Total hardness values classified most of the studied brands from moderate to very hard water.
基金Project"863":Physical Model-based Dynamic Evolution Technology of a Complex Scene(2015AA016404)the SDUST Excellent Teaching Team Construction Plan.
文摘Background Machine learning-based beer bottle-defect detection is a complex technology that runs automatically;however,it consumes considerable memory,is expensive,and poses a certain danger when training novice operators.Moreover,some topics are difficult to learn from experimental lectures,such as digital image processing and computer vision.However,virtual simulation experiments have been widely used to good effect within education.A virtual simulation of the design and manufacture of a beer bottle-defect detection system will not only help the students to increase their image-processing knowledge,but also improve their ability to solve complex engineering problems and design complex systems.Methods The hardware models for the experiment(camera,light source,conveyor belt,power supply,manipulator,and computer)were built using the 3DS MAX modeling and animation software.The Unreal Engine 4(UE4)game engine was utilized to build a virtual design room,design the interactive operations,and simulate the system operation.Results The results showed that the virtual-simulation system received much better experimental feedback,which facilitated the design and manufacture of a beer bottle-defect detection system.The specialized functions of the functional modules in the detection system,including a basic experimental operation menu,power switch,image shooting,image processing,and manipulator grasping,allowed students(or virtual designers)to easily build a detection system by retrieving basic models from the model library,and creating the beer-bottle transportation,image shooting,image processing,defect detection,and defective-product removal.The virtual simulation experiment was completed with image processing as the main body.Conclusions By mainly focusing on bottle mouth defect detection,the detection system dedicates more attention to the user and the task.With more detailed tasks available,the virtual system will eventually yield much better results as a training tool for image processing education.In addition,a novel visual perception-thinking pedagogical framework enables better comprehension than the traditional lecture-tutorial style.
基金Funded by the Ministere de I'Enseignement Superieur et de la Recherche Scientifique(MESRS),Benin and the President's Malaria Initiative of the U.S. Government through USAID
文摘Objective:To determine the efficacy of WHO impregnated paper and CDC coated bottle based on number of storage days and number of limes of consecutive use,in the assessment of insecticide vector susceptibility tests in laboratory and field conditions.Methods:Larvae and pupae of Anopheles gambiae s.l.mosquitoes were collected from the breeding sites in Seme-Kpodji and Cotonou districts in Southern Benin in April 2013 during the first rainy season.Anopheles gambiae s.l.mosquitoes were also collected from the breeding sites in Parakou district in Northern Benin in May 2013 at the beginning of the rainy season.Susceptibility tests were done using impregnated paper with bendiocarb(0.1%)following WHO protocol and stock solutions of permethrin(21.5 ug per bottle)and deltamethrin(12.5 ug per bottle)following CDC protocol on unfed female mosquitoes aged 2-5 days old.These bioassays were repeated a certain number of times.The temperature and relative humidity were monitored and recorded during the susceptibility tests.Results:This study showed that a WHO impregnated paper with bendiocarb could be used four times during four consecutive days in field conditions.Regarding a Wheaton coated bottle with permethrin or deltamethrin,they could be used at least three limes during four consecutive days in laboratory conditions.Conclusions:The day storage and the number of times that a WHO impregnated paper and a CDC coated bottle maintained their efficacy are useful in the assessment of insecticide vectors susceptibility tests.
文摘In a previous paper by the author joint with Baogang XU published in Discrete Math in 2018, we show that every non-planar toroidal graph can be edge partitioned into a planar graph and an outerplanar graph. This edge partition then implies some results in thickness and outerthickness of toroidal graphs. In particular, if each planar graph has outerthickness at most 2(conjectured by Chartrand, Geller and Hedetniemi in 1971 and the confirmation of the conjecture was announced by Gon?calves in 2005), then the outerthickness of toroidal graphs is at most 3 which is the best possible due to K7.In this paper we continue to study the edge partition for projective planar graphs and Klein bottle embeddable graphs. We show that(1) every non-planar but projective planar graph can be edge partitioned into a planar graph and a union of caterpillar trees;and(2) every non-planar Klein bottle embeddable graph can be edge partitioned into a planar graph and a subgraph of two vertex amalgamation of a caterpillar tree with a cycle with pendant edges. As consequences,the thinkness of projective planar graphs and Klein bottle embeddabe graphs are at most 2,which are the best possible, and the outerthickness of these graphs are at most 3.
