Seven cases of sarcoma botryoides of the uterine cervix are reviewed. The age of the patients ranged from 19 to 40 years, with a median age of 23 years. Four patients were diagnosed as stage Ia, two as Ib and one as ...Seven cases of sarcoma botryoides of the uterine cervix are reviewed. The age of the patients ranged from 19 to 40 years, with a median age of 23 years. Four patients were diagnosed as stage Ia, two as Ib and one as Ⅱ a, 6 cases were treated with surgery, chemotherapy and/or radiotherapy, and 1 with surgery only, 5 cases in this group survived more than 5 years with a mean 7.9 years of follow-up. The prognosis for cervical sarcoma botryoides is similar to that of other female genital tract embryonal rhabdomyosarcomas. Primary therapy should consist of vincristine and dactinomycin based chemotherapy. Surgery should be guided by the response to initial chemotherapy and should attempt to conserve the function of the bladder, rectum, vagina, and ovaries. Radiotherapy was used for involved surgical margins or positive nodes. The effect of radiotherapy is unclear for stage Ia cases.展开更多
The literature on cervical embryonal rhabdomyosarcoma(RMS)is reviewed here to identify management guidelines for middle-aged women diagnosed with this rare type of gynecologic cancer.Specifically,the Pub Med,Web of Sc...The literature on cervical embryonal rhabdomyosarcoma(RMS)is reviewed here to identify management guidelines for middle-aged women diagnosed with this rare type of gynecologic cancer.Specifically,the Pub Med,Web of Science and Google Scholar databases,were searched to find published case series on cervical embryonal RMS reporting on four or more patients,of whom at least one was>40-year-old.Theχ^(2 )test was used to assess heterogeneity.Five articles published between 1986 and 2013 were identified,reporting on a total of 47 patients,of whom 22(46.8%)were older and 25(53.2%)younger than 40-year-old.Although the two age groups did not differ significantly by stage of disease or radiotherapy treatment,the older age groupreceived less chemotherapy(55%vs 90%,P=0.008)and had more hysterectomy(86%vs 43%,P=0.009).Follow-up data was missing for 18/47(38.3%)patients.Among the 29 patients with follow-up data,survival was shorter in the older group,with 8/12(67%)alive and3 with disease at a median follow-up of 2.6 years,as compared with the younger group that had 15/17(88%)alive and none with disease at a median follow-up of 3.5years.The longest survivals among the older women were observed in those who received radiotherapy,including one case with a resected lung metastasis.A prospective multi-institutional collaboration and better follow-up are needed to determine the optimal management of cervical embryonal RMS.Long-term survival appears feasible if management is accompanied by chemotherapy and radiotherapy.展开更多
Fabric of carbonate rock is the important foundation and one of main research contents for study on carbonate sedimentology,and has always been the attention of the academic circles.Botryoidal structures from the Sini...Fabric of carbonate rock is the important foundation and one of main research contents for study on carbonate sedimentology,and has always been the attention of the academic circles.Botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin is a kind of special carbonate fabric,the fabric is named after the shape of a grape.In this paper,from four aspects of the research status,the definition of the botryoidal structures and the related terms,the construction characteristics of the botryoidal structures,the component of the botryoidal structures,geochemical characteristics and the genesis of the botryoidal structures are reviewed.It points out the current research issues of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin,and put forward that future research should focus on the accurate analysis of its internal construction,precipitation mechanism of the major components,and the construction mechanism of botryoidal structures.展开更多
文摘Seven cases of sarcoma botryoides of the uterine cervix are reviewed. The age of the patients ranged from 19 to 40 years, with a median age of 23 years. Four patients were diagnosed as stage Ia, two as Ib and one as Ⅱ a, 6 cases were treated with surgery, chemotherapy and/or radiotherapy, and 1 with surgery only, 5 cases in this group survived more than 5 years with a mean 7.9 years of follow-up. The prognosis for cervical sarcoma botryoides is similar to that of other female genital tract embryonal rhabdomyosarcomas. Primary therapy should consist of vincristine and dactinomycin based chemotherapy. Surgery should be guided by the response to initial chemotherapy and should attempt to conserve the function of the bladder, rectum, vagina, and ovaries. Radiotherapy was used for involved surgical margins or positive nodes. The effect of radiotherapy is unclear for stage Ia cases.
文摘The literature on cervical embryonal rhabdomyosarcoma(RMS)is reviewed here to identify management guidelines for middle-aged women diagnosed with this rare type of gynecologic cancer.Specifically,the Pub Med,Web of Science and Google Scholar databases,were searched to find published case series on cervical embryonal RMS reporting on four or more patients,of whom at least one was>40-year-old.Theχ^(2 )test was used to assess heterogeneity.Five articles published between 1986 and 2013 were identified,reporting on a total of 47 patients,of whom 22(46.8%)were older and 25(53.2%)younger than 40-year-old.Although the two age groups did not differ significantly by stage of disease or radiotherapy treatment,the older age groupreceived less chemotherapy(55%vs 90%,P=0.008)and had more hysterectomy(86%vs 43%,P=0.009).Follow-up data was missing for 18/47(38.3%)patients.Among the 29 patients with follow-up data,survival was shorter in the older group,with 8/12(67%)alive and3 with disease at a median follow-up of 2.6 years,as compared with the younger group that had 15/17(88%)alive and none with disease at a median follow-up of 3.5years.The longest survivals among the older women were observed in those who received radiotherapy,including one case with a resected lung metastasis.A prospective multi-institutional collaboration and better follow-up are needed to determine the optimal management of cervical embryonal RMS.Long-term survival appears feasible if management is accompanied by chemotherapy and radiotherapy.
基金This study was supported by the National Natural Science Foundation of China(Grant No.41402126)the National Science and Technology Major Project(Grant No.2016ZX05004002-001).
文摘Fabric of carbonate rock is the important foundation and one of main research contents for study on carbonate sedimentology,and has always been the attention of the academic circles.Botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin is a kind of special carbonate fabric,the fabric is named after the shape of a grape.In this paper,from four aspects of the research status,the definition of the botryoidal structures and the related terms,the construction characteristics of the botryoidal structures,the component of the botryoidal structures,geochemical characteristics and the genesis of the botryoidal structures are reviewed.It points out the current research issues of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin,and put forward that future research should focus on the accurate analysis of its internal construction,precipitation mechanism of the major components,and the construction mechanism of botryoidal structures.
