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ARF鸟苷酸交换因子BIGs对高尔基体相关的囊泡转运的调控作用
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作者 林思思 林巍 +3 位作者 王莹 周春 李翠限 沈晓燕 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2012年第3期311-315,共5页
【目的】探讨ARF鸟苷酸交换因子BIG1和BIG2在高尔基体相关囊泡转运方面的功能。【方法】利用脂质体将siRNA干扰序列转入细胞中,western blotting方法检测转染效率;利用细胞免疫荧光染色方法检测Hela细胞中BIGs蛋白水平的表达分布;采用Al... 【目的】探讨ARF鸟苷酸交换因子BIG1和BIG2在高尔基体相关囊泡转运方面的功能。【方法】利用脂质体将siRNA干扰序列转入细胞中,western blotting方法检测转染效率;利用细胞免疫荧光染色方法检测Hela细胞中BIGs蛋白水平的表达分布;采用Alexa568标记的转铁蛋白孵育Hela细胞,检测转铁蛋白相关的内吞体循环;利用脂质体转染VSVG-YFP病毒质粒,检测新生蛋白经从内质网经高尔基体转运至胞膜的途径。【结果】BIG1和BIG2的siRNA干扰效率均高于70%,且特异性良好;干扰掉BIGs后,细胞内TGN230结构变松散,呈现短片状或点状;干扰BIG2可导致细胞内转铁蛋白的积聚,而同时干扰BIG1则可进-步加剧转铁蛋白的积聚;BIG1或/和BIG2干扰均抑制了新生蛋白的从内质网向高尔基及细胞表面的转运过程。【结论】BIGs蛋白主要位于反面高尔基体网络,对维持其结构完整性非常重要;它们均参与调控高尔基体相关的囊泡转运,两者具有协同作用。 展开更多
关键词 RNAI bigs 反面高尔基体网络 囊泡转运 VSVG—YFP
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王星、梁飞:苏州的双面——守成与创造之间的城市精神
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作者 王星 梁飞 《建筑实践》 2026年第1期175-175,共1页
遇到很多人,他们提到苏州的话语里,最多的是关于苏州的园林,苏州的东方之门。从工业园区到古城,仿佛能感受到时间的流动—一个现代化的城市转瞬切换慢生活的古城。苏州的“当代性”从不表现为与传统决裂的激进。相反,它擅长一种“慢生... 遇到很多人,他们提到苏州的话语里,最多的是关于苏州的园林,苏州的东方之门。从工业园区到古城,仿佛能感受到时间的流动—一个现代化的城市转瞬切换慢生活的古城。苏州的“当代性”从不表现为与传统决裂的激进。相反,它擅长一种“慢生长”式的转译。在苏州工业园区由BIG设计的当代美术馆里,我看到的不只是新颖的建筑形态,更是设计思维与江南水乡肌理的细腻对话;而在古城区由贝聿铭设计的苏州博物馆中,我看到建筑的低调介入让创新自然而然地“长”在了这片土地上。 展开更多
关键词 慢生活 古城 苏州 园林 现代化 BIG设计 当代性
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Spatio-Temporal Earthquake Analysis via Data Warehousing for Big Data-Driven Decision Systems
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作者 Georgia Garani George Pramantiotis Francisco Javier Moreno Arboleda 《Computers, Materials & Continua》 2026年第3期1963-1988,共26页
Earthquakes are highly destructive spatio-temporal phenomena whose analysis is essential for disaster preparedness and risk mitigation.Modern seismological research produces vast volumes of heterogeneous data from sei... Earthquakes are highly destructive spatio-temporal phenomena whose analysis is essential for disaster preparedness and risk mitigation.Modern seismological research produces vast volumes of heterogeneous data from seismic networks,satellite observations,and geospatial repositories,creating the need for scalable infrastructures capable of integrating and analyzing such data to support intelligent decision-making.Data warehousing technologies provide a robust foundation for this purpose;however,existing earthquake-oriented data warehouses remain limited,often relying on simplified schemas,domain-specific analytics,or cataloguing efforts.This paper presents the design and implementation of a spatio-temporal data warehouse for seismic activity.The framework integrates spatial and temporal dimensions in a unified schema and introduces a novel array-based approach for managing many-to-many relationships between facts and dimensions without intermediate bridge tables.A comparative evaluation against a conventional bridge-table schema demonstrates that the array-based design improves fact-centric query performance,while the bridge-table schema remains advantageous for dimension-centric queries.To reconcile these trade-offs,a hybrid schema is proposed that retains both representations,ensuring balanced efficiency across heterogeneous workloads.The proposed framework demonstrates how spatio-temporal data warehousing can address schema complexity,improve query performance,and support multidimensional visualization.In doing so,it provides a foundation for integrating seismic analysis into broader big data-driven intelligent decision systems for disaster resilience,risk mitigation,and emergency management. 展开更多
关键词 Data warehouse data analysis big data decision systems SEISMOLOGY data visualization
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“Big question+问题链”:激活语篇学习内驱力五步走——以译林版英语教材六年级上册Unit 4 Then and now中Story time的教学为例
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作者 潘小琴 《小学教学参考》 2026年第6期48-51,共4页
在小学高年级英语语篇教学中,存在学生思维浅表化、问题设计碎片化、旧版教材适配难这三个痛点。以译林版英语教材六年级上册Unit 4 Then and now中Story time的教学为例,教师立足教材文本,构建“课前定问—课初引链—课中解链—课后拓... 在小学高年级英语语篇教学中,存在学生思维浅表化、问题设计碎片化、旧版教材适配难这三个痛点。以译林版英语教材六年级上册Unit 4 Then and now中Story time的教学为例,教师立足教材文本,构建“课前定问—课初引链—课中解链—课后拓链—全程评链”的五步闭环,用大问题拉主线、小问题搭台阶,能激活学生语篇学习内驱力,实现英语教学从“知识传递”到“素养培养”的转变。 展开更多
关键词 Big question 问题链 内驱力 语篇教学
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Research on the Optimal Allocation of Community Elderly Care Service Resources Based on Big Data Technology
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作者 Shuying Li 《Journal of Clinical and Nursing Research》 2026年第1期241-246,共6页
With the accelerating aging process of China’s population,the demand for community elderly care services has shown diversified and personalized characteristics.However,problems such as insufficient total care service... With the accelerating aging process of China’s population,the demand for community elderly care services has shown diversified and personalized characteristics.However,problems such as insufficient total care service resources,uneven distribution,and prominent supply-demand contradictions have seriously affected service quality.Big data technology,with core advantages including data collection,analysis and mining,and accurate prediction,provides a new solution for the allocation of community elderly care service resources.This paper systematically studies the application value of big data technology in the allocation of community elderly care service resources from three aspects:resource allocation efficiency,service accuracy,and management intelligence.Combined with practical needs,it proposes optimal allocation strategies such as building a big data analysis platform and accurately grasping the elderly’s care needs,striving to provide operable path references for the construction of community elderly care service systems,promoting the early realization of the elderly care service goal of“adequate support and proper care for the elderly”,and boosting the high-quality development of China’s elderly care service industry. 展开更多
关键词 Big data technology COMMUNITY Elderly care Service resources
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Current Situation of Application and Development Prospects of the Statistical Analysis of Big Data
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作者 Zhuoran LI 《Meteorological and Environmental Research》 2026年第1期45-47,共3页
With the advent of the big data era,modern statistics has enjoyed unprecedented development opportunities and also faced numerous new challenges.Traditional statistical computing methods are often limited by issues su... With the advent of the big data era,modern statistics has enjoyed unprecedented development opportunities and also faced numerous new challenges.Traditional statistical computing methods are often limited by issues such as computer memory capacity and distributed storage of data across different locations,and are unable to directly apply to large-scale data sets.Therefore,in the context of big data,designing efficient and theoretically guaranteed statistical learning and inference algorithms has become a key issue that the current field of statistics urgently needs to address.In this paper,the application status of statistical analysis methods in the big data environment was systematically reviewed,and its future development directions were analyzed to provide reference and support for the further development of theory and methods of the statistical analysis of big data. 展开更多
关键词 Big data Statistical analysis Current status Development prospects
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Corrosion behavior of 650 MPa high strength low alloy steel in industrial polluted environments containing different concentrations of Cl^(-)
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作者 Lianjun Hao Xiaokun Cai +4 位作者 Tianqi Chen Chenyu Zhang Chao Liu Xuequn Cheng Xiaogang Li 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期228-241,共14页
This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low... This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low-alloy(HSLA)steel in industrially polluted environments.The corrosion process of 650 MPa HSLA steel occurred in two distinct stages:an initial corrosion stage and a stable corrosion stage.During the initial phase,the weight loss rate increased rapidly owing to the instability of the rust layer.Notably,this study demonstrated that 650 MPa HSLA steel exhibited superior corrosion resistance in Cl-containing environments.The formation of a corrosion-product film eventually reduced the weight-loss rate.However,the intrusion of Cl^(-)at increasing concentrations gradually destabilized theα/γ^(*)phases of the rust layer,leading to a looser structure and lower polarization resistance(R_(p)).The application of corrosion big data technology in this study facilitated the validation and analysis of the experimental results,offering new insights into the corrosion mechanisms of HSLA steel in chloride-rich environments. 展开更多
关键词 HSLA steel CHLORINE corrosion behavior corrosion big data
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飞利浦Brilliance Big Bore CT常见故障维修两例
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作者 张杰 谭启良 肖鹏 《医疗装备》 2026年第2期91-93,共3页
大孔径CT基于X线断层扫描原理的超大孔径设计,能容纳肥胖患者以及携带医疗设备的特殊患者,其凭借高清晰成像为放疗计划的制定与实施提供了关键的解剖学依据,是现代放疗“精准化”转型的重要支撑[1]。我院于2017年引进飞利浦Brilliance B... 大孔径CT基于X线断层扫描原理的超大孔径设计,能容纳肥胖患者以及携带医疗设备的特殊患者,其凭借高清晰成像为放疗计划的制定与实施提供了关键的解剖学依据,是现代放疗“精准化”转型的重要支撑[1]。我院于2017年引进飞利浦Brilliance Big Bore CT设备,截至2024年底,已累计完成5000余例肿瘤患者的放疗定位扫描。 展开更多
关键词 Brilliance Big Bore CT 飞利浦 网络故障 伪影 故障维修
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Big Data-Driven Federated Learning Model for Scalable and Privacy-Preserving Cyber Threat Detection in IoT-Enabled Healthcare Systems
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作者 Noura Mohammed Alaskar Muzammil Hussain +3 位作者 Saif Jasim Almheiri Atta-ur-Rahman Adnan Khan Khan M.Adnan 《Computers, Materials & Continua》 2026年第4期793-816,共24页
The increasing number of interconnected devices and the incorporation of smart technology into contemporary healthcare systems have significantly raised the attack surface of cyber threats.The early detection of threa... The increasing number of interconnected devices and the incorporation of smart technology into contemporary healthcare systems have significantly raised the attack surface of cyber threats.The early detection of threats is both necessary and complex,yet these interconnected healthcare settings generate enormous amounts of heterogeneous data.Traditional Intrusion Detection Systems(IDS),which are generally centralized and machine learning-based,often fail to address the rapidly changing nature of cyberattacks and are challenged by ethical concerns related to patient data privacy.Moreover,traditional AI-driven IDS usually face challenges in handling large-scale,heterogeneous healthcare data while ensuring data privacy and operational efficiency.To address these issues,emerging technologies such as Big Data Analytics(BDA)and Federated Learning(FL)provide a hybrid framework for scalable,adaptive intrusion detection in IoT-driven healthcare systems.Big data techniques enable processing large-scale,highdimensional healthcare data,and FL can be used to train a model in a decentralized manner without transferring raw data,thereby maintaining privacy between institutions.This research proposes a privacy-preserving Federated Learning–based model that efficiently detects cyber threats in connected healthcare systems while ensuring distributed big data processing,privacy,and compliance with ethical regulations.To strengthen the reliability of the reported findings,the resultswere validated using cross-dataset testing and 95%confidence intervals derived frombootstrap analysis,confirming consistent performance across heterogeneous healthcare data distributions.This solution takes a significant step toward securing next-generation healthcare infrastructure by combining scalability,privacy,adaptability,and earlydetection capabilities.The proposed global model achieves a test accuracy of 99.93%±0.03(95%CI)and amiss-rate of only 0.07%±0.02,representing state-of-the-art performance in privacy-preserving intrusion detection.The proposed FL-driven IDS framework offers an efficient,privacy-preserving,and scalable solution for securing next-generation healthcare infrastructures by combining adaptability,early detection,and ethical data management. 展开更多
关键词 Intrusion detection systems cyber threat detection explainable AI big data analytics federated learning
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“Big Question”驱动式小学英语项目学习研究
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作者 陈向红 《文理导航》 2026年第9期4-6,共3页
新课标倡导“主题化、项目式学习等综合性教学活动”的积极开展,“Big Question”驱动下的项目学习正是对这一要求的直接回应。这既能将小学英语课堂学习的主动权交到学生手中,又能确保其自主学习方向不偏航,驱动学生不断走向深度学习... 新课标倡导“主题化、项目式学习等综合性教学活动”的积极开展,“Big Question”驱动下的项目学习正是对这一要求的直接回应。这既能将小学英语课堂学习的主动权交到学生手中,又能确保其自主学习方向不偏航,驱动学生不断走向深度学习。本文提出四项有效策略,以供广大教育工作者参考。 展开更多
关键词 “Big Question” 小学英语 项目化学习
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Empowering Edge Computing:Public Edge as a Service for Performance and Cost Optimization
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作者 Ateeqa Jalal Umar Farooq +4 位作者 Ihsan Rabbi Afzal Badshah Aurangzeb Khan Muhammad Mansoor Alam Mazliham Mohd Su’ud 《Computers, Materials & Continua》 2026年第2期1784-1802,共19页
The exponential growth of Internet of Things(IoT)devices,autonomous systems,and digital services is generating massive volumes of big data,projected to exceed 291 zettabytes by 2027.Conventional cloud computing,despit... The exponential growth of Internet of Things(IoT)devices,autonomous systems,and digital services is generating massive volumes of big data,projected to exceed 291 zettabytes by 2027.Conventional cloud computing,despite its high processing and storage capacity,suffers from increased network latency,network congestion,and high operational costs,making it unsuitable for latency-sensitive applications.Edge computing addresses these issues by processing data near the source but faces scalability challenges and elevated Total Cost of Ownership(TCO).Hybrid solutions,such as fog computing,cloudlets,and Mobile Edge Computing(MEC),attempt to balance cost and performance;however,they still struggle with limited resource sharing and high deployment expenses.This paper proposes Public Edge as a Service(PEaaS),a novel paradigm that utilizes idle resources contributed by universities,enterprises,cellular operators,and individuals under a collaborative service model.By decentralizing computation and enabling multi-tenant resource sharing,PEaaS reduces reliance on centralized cloud infrastructure,minimizes communication costs,and enhances scalability.The proposed framework is evaluated using EdgeCloudSim under varying workloads,for keymetrics such as latency,communication cost,server utilization,and task failure rate.Results reveal that while cloud has a task failure rate rising sharply to 12.3%at 2000 devices,PEaaS maintains a low rate of 2.5%,closely matching edge computing.Furthermore,communication costs remain 25% lower than cloud and latency remains below 0.3,even under peak load.These findings demonstrate that PEaaS achieves near-edge performance with reduced costs and enhanced scalability,offering a sustainable and economically viable solution for next-generation computing environments. 展开更多
关键词 Big data edge as a service edge computing
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Construction and Application Practice of the Data-driven Comprehensive Management Platform for Regional Air Quality
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作者 Tongxing ZHANG Yun WU Yongwen LI 《Meteorological and Environmental Research》 2026年第1期21-28,共8页
To address the severe challenges of PM_(2.5) and ozone co-control during the"14^(th) Five-Year Plan"period and to enhance the precision and intelligence level of air environment governance,it is imperative t... To address the severe challenges of PM_(2.5) and ozone co-control during the"14^(th) Five-Year Plan"period and to enhance the precision and intelligence level of air environment governance,it is imperative to build an efficient comprehensive management platform for regional air quality.In this paper,the specific practice in Zibo City,Shandong Province is as an example to systematically analyze the top-level design,technical implementation,and innovative application of a comprehensive management platform for regional air quality integrating"perception monitoring,data fusion,research judgment of early warnings,analysis of sources,collaborative dispatching,and evaluation assessment".Through the construction of an"sky-air-ground"integrated three-dimensional monitoring network,the platform integrates multi-source heterogeneous environmental data,and employs big data,cloud computing,artificial intelligence,CALPUFF/CMAQ,and other numerical model technologies to achieve comprehensive perception,precise prediction,intelligent source tracing,and closed-loop management of air pollution.The platform innovatively establishes a full-process closed-loop management mechanism of"data-early warning-disposition-evaluation",and achieves a fundamental transformation from passive response to active anticipation and from experience-based judgment to data driving in environmental supervision.The application results show that this platform significantly improves the scientific decision-making ability and collaborative execution efficiency of air pollution governance in Zibo City,providing a replicable and scalable comprehensive solution for similar industrial cities to achieve the continuous improvement of air quality. 展开更多
关键词 Comprehensive management of air quality Big data Internet of Things Closed-loop management Data driving Off-site supervision
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Big data-driven analysis of shale gas enrichment patterns:A case study of the Wufeng–Longmaxi Formation in the Sichuan Basin and its periphery
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作者 Zongquan Hu Jin Meng +10 位作者 Wei Du Yitian Xiao Chuanxiang Sun Guanping Wang Baojian Shen Tianrui Ye Dongjun Feng Zengqin Liu Longfei Lu Ruyue Wang Qianru Wang 《Energy Geoscience》 2026年第1期166-178,共13页
The Wufeng–Longmaxi Formation derives its name from the Upper Ordovician Wufeng Formation and the Lower Silurian Longmaxi Formation,found in sequence in the Sichuan Basin.This formation hosts rich shale gas reservoir... The Wufeng–Longmaxi Formation derives its name from the Upper Ordovician Wufeng Formation and the Lower Silurian Longmaxi Formation,found in sequence in the Sichuan Basin.This formation hosts rich shale gas reservoirs,and its shale gas enrichment patterns are examined in this study using data from 1197 shale samples collected from 14 wells.Five basic and three key parameters,eight in all,are assessed for each sample.The five basic parameters include burial depth and the contents of four mineral types—quartz,clay,carbonate,and other minerals;the three key parameters,representing shale gas enrichment,are total organic carbon(TOC)content,porosity,and gas content.The SHapley Additive exPlanations(SHAP)analysis originated in game theory is used here in an interpretable machine learning framework,to address issues of heterogeneous data structure,noisy relationships,and multi-objective optimization.An evaluation of the ranking,contribution values,and conditions of changes for these parameters offers new quantitative insights into shale gas enrichment patterns.A quantitative analysis of the relationship between data-sets identifies the primary factors controlling TOC,porosity,and gas content of shale gas reservoirs.The results show that TOC and porosity jointly influence gas content;mineral content has a significant impact on both,TOC and porosity;and the burial depth governs porosity which,in turn,affects the conditions under which shale gas is preserved.Input parameter thresholds are also determined and provide a basis for the establishment of quantitative criteria to evaluate shale gas enrichment.The predictive accuracy of the model used in this study is significantly improved by the step-wise addition of two input parameters,namely TOC and porosity,separately and together.Thus,the game theory method in big data-driven analysis uses a combination of TOC and porosity to evaluate the gas content with encouraging results—suggesting that these are the key parameters that indicate source rock and reservoir properties. 展开更多
关键词 Big data-driven analysis Primary controlling factor Shale gas enrichment pattern Wufeng–Longmaxi Formation Sichuan basin
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FaW TOKYO 2026: Japan’s largest fashion trade show expands with 9 specialised shows
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《China Textile》 2026年第1期52-53,共2页
RX Japan GK is pleased to announce that visitor registration is now open for the 29th edition of FaW TOKYO–FASHION WORLD TOKYO 2026 APRIL,an international fashion trade show and Japan’s largest fashion trade show,ta... RX Japan GK is pleased to announce that visitor registration is now open for the 29th edition of FaW TOKYO–FASHION WORLD TOKYO 2026 APRIL,an international fashion trade show and Japan’s largest fashion trade show,taking place from April 8 to 10,2026,at Tokyo Big Sight,featuring 9 specialized shows covering a wide range of the fashion industry and welcoming an expected 700 exhibitors from 20 countries and regions and 20,000 visitors from 50 countries and regions. 展开更多
关键词 japans largest fashion trade show Tokyo Big Sight visitor registration exhibitors international fashion trade show FAW Tokyo specialized shows fashion trade show
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JIMTOF2024展会报告(上)
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作者 符祚钢 《世界制造技术与装备市场》 2025年第1期54-60,共7页
2024年日本机床展览会(JIMTOF2024)于2024年11月5~10日在东京Tokyo Big Sight举办,展出面积118540平方米。展会以“技术传承提供无限可能(Technologies passed down to the future offer unlimited possibilities)”为主题。
关键词 technologies passed down JIMTOF machine tool exhibition tokyo big sight unlimited possibilities
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Research Status of High-Entropy Alloys Based on Artificial Intelligence Technology 被引量:3
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作者 YU Zhiqi ZHAO Yanchun +5 位作者 XUE Baorui DANG Wenxia MA Huwen SU Yu LAN Yunbo FENG Li 《有色金属(中英文)》 北大核心 2025年第5期735-747,共13页
High-Entropy Alloys(HEAs)exhibit significant potential across multiple domains due to their unique properties.However,conventional research methodologies face limitations in composition design,property prediction,and ... High-Entropy Alloys(HEAs)exhibit significant potential across multiple domains due to their unique properties.However,conventional research methodologies face limitations in composition design,property prediction,and process optimization,characterized by low efficiency and high costs.The integration of Artificial Intelligence(AI)technologies has provided innovative solutions for HEAs research.This review presented a detailed overview of recent advancements in AI applications for structural modeling and mechanical property prediction of HEAs.Furthermore,it discussed the advantages of big data analytics in facilitating alloy composition design and screening,quality control,and defect prediction,as well as the construction and sharing of specialized material databases.The paper also addressed the existing challenges in current AI-driven HEAs research,including issues related to data quality,model interpretability,and cross-domain knowledge integration.Additionally,it proposed prospects for the synergistic development of AI-enhanced computational materials science and experimental validation systems. 展开更多
关键词 high-entropy alloys artificial intelligence structural modeling mechanical property big data
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Integration of data science with the intelligent IoT(IIoT):Current challenges and future perspectives 被引量:4
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作者 Inam Ullah Deepak Adhikari +3 位作者 Xin Su Francesco Palmieri Celimuge Wu Chang Choi 《Digital Communications and Networks》 2025年第2期280-298,共19页
The Intelligent Internet of Things(IIoT)involves real-world things that communicate or interact with each other through networking technologies by collecting data from these“things”and using intelligent approaches,s... The Intelligent Internet of Things(IIoT)involves real-world things that communicate or interact with each other through networking technologies by collecting data from these“things”and using intelligent approaches,such as Artificial Intelligence(AI)and machine learning,to make accurate decisions.Data science is the science of dealing with data and its relationships through intelligent approaches.Most state-of-the-art research focuses independently on either data science or IIoT,rather than exploring their integration.Therefore,to address the gap,this article provides a comprehensive survey on the advances and integration of data science with the Intelligent IoT(IIoT)system by classifying the existing IoT-based data science techniques and presenting a summary of various characteristics.The paper analyzes the data science or big data security and privacy features,including network architecture,data protection,and continuous monitoring of data,which face challenges in various IoT-based systems.Extensive insights into IoT data security,privacy,and challenges are visualized in the context of data science for IoT.In addition,this study reveals the current opportunities to enhance data science and IoT market development.The current gap and challenges faced in the integration of data science and IoT are comprehensively presented,followed by the future outlook and possible solutions. 展开更多
关键词 Data science Internet of things(IoT) Big data Communication systems Networks Security Data science analytics
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Revolutionizing Crop Breeding:Next-Generation Artificial Intelligence and Big Data-Driven Intelligent Design 被引量:4
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作者 Ying Zhang Guanmin Huang +5 位作者 Yanxin Zhao Xianju Lu Yanru Wang Chuanyu Wang Xinyu Guo Chunjiang Zhao 《Engineering》 2025年第1期245-255,共11页
The security of the seed industry is crucial for ensuring national food security.Currently,developed countries in Europe and America,along with international seed industry giants,have entered the Breeding 4.0 era.This... The security of the seed industry is crucial for ensuring national food security.Currently,developed countries in Europe and America,along with international seed industry giants,have entered the Breeding 4.0 era.This era integrates biotechnology,artificial intelligence(AI),and big data information technology.In contrast,China is still in a transition period between stages 2.0 and 3.0,which primarily relies on conventional selection and molecular breeding.In the context of increasingly complex international situations,accurately identifying core issues in China's seed industry innovation and seizing the frontier of international seed technology are strategically important.These efforts are essential for ensuring food security and revitalizing the seed industry.This paper systematically analyzes the characteristics of crop breeding data from artificial selection to intelligent design breeding.It explores the applications and development trends of AI and big data in modern crop breeding from several key perspectives.These include highthroughput phenotype acquisition and analysis,multiomics big data database and management system construction,AI-based multiomics integrated analysis,and the development of intelligent breeding software tools based on biological big data and AI technology.Based on an in-depth analysis of the current status and challenges of China's seed industry technology development,we propose strategic goals and key tasks for China's new generation of AI and big data-driven intelligent design breeding.These suggestions aim to accelerate the development of an intelligent-driven crop breeding engineering system that features large-scale gene mining,efficient gene manipulation,engineered variety design,and systematized biobreeding.This study provides a theoretical basis and practical guidance for the development of China's seed industry technology. 展开更多
关键词 Crop breeding Next-generation artificial intelligence Multiomics big data Intelligent design breeding
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Smart cities,smart systems:A comprehensive review of system dynamics model applications in urban studies in the big data era 被引量:2
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作者 Gift Fabolude Charles Knoble +1 位作者 Anvy Vu Danlin Yu 《Geography and Sustainability》 2025年第1期25-36,共12页
This paper addresses urban sustainability challenges amid global urbanization, emphasizing the need for innova tive approaches aligned with the Sustainable Development Goals. While traditional tools and linear models ... This paper addresses urban sustainability challenges amid global urbanization, emphasizing the need for innova tive approaches aligned with the Sustainable Development Goals. While traditional tools and linear models offer insights, they fall short in presenting a holistic view of complex urban challenges. System dynamics (SD) models that are often utilized to provide holistic, systematic understanding of a research subject, like the urban system, emerge as valuable tools, but data scarcity and theoretical inadequacy pose challenges. The research reviews relevant papers on recent SD model applications in urban sustainability since 2018, categorizing them based on nine key indicators. Among the reviewed papers, data limitations and model assumptions were identified as ma jor challenges in applying SD models to urban sustainability. This led to exploring the transformative potential of big data analytics, a rare approach in this field as identified by this study, to enhance SD models’ empirical foundation. Integrating big data could provide data-driven calibration, potentially improving predictive accuracy and reducing reliance on simplified assumptions. The paper concludes by advocating for new approaches that reduce assumptions and promote real-time applicable models, contributing to a comprehensive understanding of urban sustainability through the synergy of big data and SD models. 展开更多
关键词 Urban sustainability Smart cities System dynamics models Big data analytics Urban system complexity Data-driven urbanism
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Methodology,progress and challenges of geoscience knowledge graph in International Big Science Program of Deep-Time Digital Earth 被引量:2
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作者 ZHU Yunqiang WANG Qiang +9 位作者 WANG Shu SUN Kai WANG Xinbing LV Hairong HU Xiumian ZHANG Jie WANG Bin QIU Qinjun YANG Jie ZHOU Chenghu 《Journal of Geographical Sciences》 2025年第5期1132-1156,共25页
Deep-time Earth research plays a pivotal role in deciphering the rates,patterns,and mechanisms of Earth's evolutionary processes throughout geological history,providing essential scientific foundations for climate... Deep-time Earth research plays a pivotal role in deciphering the rates,patterns,and mechanisms of Earth's evolutionary processes throughout geological history,providing essential scientific foundations for climate prediction,natural resource exploration,and sustainable planetary stewardship.To advance Deep-time Earth research in the era of big data and artificial intelligence,the International Union of Geological Sciences initiated the“Deeptime Digital Earth International Big Science Program”(DDE)in 2019.At the core of this ambitious program lies the development of geoscience knowledge graphs,serving as a transformative knowledge infrastructure that enables the integration,sharing,mining,and analysis of heterogeneous geoscience big data.The DDE knowledge graph initiative has made significant strides in three critical dimensions:(1)establishing a unified knowledge structure across geoscience disciplines that ensures consistent representation of geological entities and their interrelationships through standardized ontologies and semantic frameworks;(2)developing a robust and scalable software infrastructure capable of supporting both expert-driven and machine-assisted knowledge engineering for large-scale graph construction and management;(3)implementing a comprehensive three-tiered architecture encompassing basic,discipline-specific,and application-oriented knowledge graphs,spanning approximately 20 geoscience disciplines.Through its open knowledge framework and international collaborative network,this initiative has fostered multinational research collaborations,establishing a robust foundation for next-generation geoscience research while propelling the discipline toward FAIR(Findable,Accessible,Interoperable,Reusable)data practices in deep-time Earth systems research. 展开更多
关键词 deep-time Earth geoscience knowledge graph Deep-time Digital Earth International Big Science Program
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