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NONLINEAR BENDINGS FOR THE ORTHOTROPIC RECTANGULAR THIN PLATES UNDER VARIOUS SUPPORTS
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作者 周次青 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1984年第3期1383-1397,共15页
In this paper, the nonlinear bandings for the orthotropic rectangular thin plates under various supports are studied.The uniformly valid asymptotic solutions of the displacement ? and stress function φ are derived by... In this paper, the nonlinear bandings for the orthotropic rectangular thin plates under various supports are studied.The uniformly valid asymptotic solutions of the displacement ? and stress function φ are derived by the perturbation offered in [1]. 展开更多
关键词 NONLINEAR bendings FOR THE ORTHOTROPIC RECTANGULAR THIN PLATES UNDER VARIOUS SUPPORTS
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补阳还五汤通过小窝蛋白1调控YAP1/HIF-1α信号通路促进bEnd.3细胞糖氧剥夺/复氧损伤后血管新生的机制研究 被引量:1
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作者 陈博威 欧阳银 +5 位作者 曾繁佐 刘英飞 田丰铭 徐雅倩 易健 刘柏炎 《中国中药杂志》 北大核心 2025年第14期3847-3856,共10页
基于小窝蛋白1(Cav1)/Yes-相关蛋白同源癌蛋白1(YAP1)/缺氧诱导因子-1α(HIF-1α)信号通路探讨补阳还五汤促进小鼠脑微血管内皮细胞株(bEnd.3)糖氧剥夺/复氧(OGD/R)损伤后血管新生的作用机制。运用超高效液相色谱-四极杆-飞行时间质谱... 基于小窝蛋白1(Cav1)/Yes-相关蛋白同源癌蛋白1(YAP1)/缺氧诱导因子-1α(HIF-1α)信号通路探讨补阳还五汤促进小鼠脑微血管内皮细胞株(bEnd.3)糖氧剥夺/复氧(OGD/R)损伤后血管新生的作用机制。运用超高效液相色谱-四极杆-飞行时间质谱联用仪(UPLC-Q-TOF-MS)分析补阳还五汤入血成分。采用胆囊收缩素八肽(CCK-8)法检测bEnd.3细胞OGD/R损伤后补阳还五汤含药血清的最佳干预浓度。慢病毒转染的方式构建Cav1沉默稳转株,Western blot法及PCR法验证沉默效率。将对照bEnd.3细胞分为正常组(sh-NC control组)、OGD/R模型+空白血清组(sh-NC OGD/R组)及OGD/R模型+含药血清组(sh-NC BHD组),Cav1沉默细胞分为OGD/R模型+空白血清组(sh-Cav1 OGD/R组)及OGD/R模型+含药血清组(sh-Cav1 BHD组),通过CCK-8法检测细胞存活率,细胞迁移实验检测细胞迁移能力,管腔形成实验检测细胞成管能力,流式细胞术检测细胞凋亡率,Western blot法检测各组细胞YAP1/HIF-1α信号通路相关蛋白的表达情况,最后运用免疫共沉淀法验证YAP1与HIF-1α之间的互作关系。结果显示补阳还五汤中黄芪甲苷、芒柄花素、阿魏酸及芍药内酯苷均能入血。质量分数10%的补阳还五汤含药血清可能是OGD/R诱导损伤bEnd.3细胞的最佳干预浓度。与sh-NC control组比较,sh-NC OGD/R组细胞存活率、细胞迁移率、网眼数、节点数和管腔长度明显下降,细胞凋亡率明显上升,YAP1的S127位点磷酸化水平明显下降,YAP1的核位移水平与HIF-1α、血管内皮生长因子(VEGF)及VEGFR2的蛋白表达明显上升;与同类型OGD/R组比较,sh-NC BHD组及sh-Cav1 BHD组细胞存活率、细胞迁移率、网眼数、节点数和管腔长度明显升高,细胞凋亡率明显下降,YAP1的S127位点磷酸化水平进一步下降,YAP1的核位移水平与HIF-1α、血管内皮生长因子(VEGF)及VEGFR2的蛋白表达明显上升;与sh-NC OGD/R组比较,sh-Cav1 OGD/R组细胞存活率、细胞迁移率、网眼数、节点数和管腔长度明显下降,细胞凋亡率明显上升,YAP1的S127位点磷酸化水平明显上升,YAP1的核位移水平与HIF-1α、VEGF及VEGFR2的蛋白表达明显下降;与sh-NC BHD组比较,sh-Cav1 BHD组细胞存活率、细胞迁移率、网眼数、节点数和管腔长度明显下降,细胞凋亡率明显上升,YAP1的S127位点磷酸化水平明显上升,YAP1的核位移水平与HIF-1α、VEGF及VEGFR2的蛋白表达明显下降。在HIF-1α抗体沉淀的蛋白复合物中存在YAP1蛋白,而在YAP1抗体沉淀的蛋白复合物中亦存在HIF-1α蛋白。结论证实补阳还五汤含药血清能够通过Cav1提高OGD/R损伤bEnd.3细胞YAP1/HIF-1α通路的活性,促进体外血管新生。 展开更多
关键词 补阳还五汤 小窝蛋白1 YAP1/HIF-1α信号通路 bEnd.3细胞 糖氧剥夺/复氧损伤 血管新生
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含“益宫清”奶牛血清缓解奶牛子宫内膜上皮细胞炎症损伤的作用机制
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作者 于书凝 王建发 +3 位作者 连帅 解颖颖 武瑞 胡学权 《东北农业大学学报》 北大核心 2025年第2期80-88,共9页
选用大庆市杜尔伯特牛场奶牛,筛选“益宫清”治疗奶牛子宫内膜炎的最佳剂量,并制备含药血清。将含药血清作用于经LPS处理的奶牛子宫内膜上皮细胞(BEND),通过蛋白组学分析筛选差异蛋白,探究其作用机制。结果表明:高剂量组(质量浓度为220 ... 选用大庆市杜尔伯特牛场奶牛,筛选“益宫清”治疗奶牛子宫内膜炎的最佳剂量,并制备含药血清。将含药血清作用于经LPS处理的奶牛子宫内膜上皮细胞(BEND),通过蛋白组学分析筛选差异蛋白,探究其作用机制。结果表明:高剂量组(质量浓度为220 g·L^(-1))治疗效果最佳,并按此剂量制备含药血清;体外试验表明,益宫清可显著降低LPS诱导的BEND细胞炎症因子表达水平;蛋白组学分析结果共鉴定出7 342个相关差异蛋白;GO富集分析显示,差异蛋白主要富集在生物进程和抗氧化过程等;KEGG聚类分析显示,差异蛋白主要涉及PPAR、AMPK、NFκB等信号通路;验证差异显著蛋白NFκB2、NκIRAS2,与蛋白质组学结果一致,表明益宫清可能通过上调NFκB2及下调NκIRAS2蛋白发挥抗炎作用。 展开更多
关键词 益宫清 BEND细胞 蛋白质组学 炎症 作用机制
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Flexural Performance of UHPC-Reinforced Concrete T-Beams:Experimental and Numerical Investigations 被引量:1
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作者 Guangqing Xiao Xilong Chen +2 位作者 Lihai Xu Feilong Kuang Shaohua He 《Structural Durability & Health Monitoring》 2025年第5期1167-1181,共15页
This study investigates the flexural performance of ultra-high performance concrete(UHPC)in reinforced concrete T-beams,focusing on the effects of interfacial treatments.Three concrete T-beam specimens were fabricated... This study investigates the flexural performance of ultra-high performance concrete(UHPC)in reinforced concrete T-beams,focusing on the effects of interfacial treatments.Three concrete T-beam specimens were fabricated and tested:a control beam(RC-T),a UHPC-reinforced beam with a chiseled interface(UN-C-50F),and a UHPC-reinforced beam featuring both a chiseled interface and anchored steel rebars(UN-CS-50F).The test results indicated that both chiseling and the incorporation of anchored rebars effectively created a synergistic combination between the concrete T-beam and the UHPC reinforcement layer,with the UN-CS-50F exhibiting the highest flexural resistance.The cracking load and ultimate load of UN-CS-50F were 221.5%and 40.8%,respectively,higher than those of the RC-T.Finite element(FE)models were developed to provide further insights into the behavior of the UHPCreinforced T-beams,showing a maximumdeviation of just 8%when validated against experimental data.A parametric analysis varied the height,thickness,andmaterial strength of the UHPC reinforcement layer based on the validated FE model,revealing that increasing the UHPC layer thickness from 30 to 50 mm improved the ultimate resistance by 20%while reducing the UHPC reinforcement height from 440 to 300 mm led to a 10%decrease in bending resistance.The interfacial anchoring rebars significantly reduced crack propagation and enhanced stress redistribution,highlighting the importance of strengthening interfacial bonds and optimizing geometric parameters ofUHPCfor improved T-beam performance.These findings offer valuable insights for the design and retrofitting of UHPC-reinforced bridge girders. 展开更多
关键词 UHPC thin layer T-BEAM REINFORCEMENT bending performance numerical simulation
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Galerkin-Vlasov approach for bending analysis of flexoelectric doubly-curved sandwich nanoshells with piezoelectric/FGP/piezoelectric layers using the nonlocal strain theory 被引量:1
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作者 Tran Van Ke Do Van Thom +2 位作者 Nguyen Thai Dung Nguyen Van Chinh Phung Van Minh 《Acta Mechanica Sinica》 2025年第2期7-40,共34页
Flexoelectricity refers to the link between electrical polarization and strain gradient fields in piezoelectric materials,particularly at the nano-scale.The present investigation aims to comprehensively focus on the s... Flexoelectricity refers to the link between electrical polarization and strain gradient fields in piezoelectric materials,particularly at the nano-scale.The present investigation aims to comprehensively focus on the static bending analysis of a piezoelectric sandwich functionally graded porous(FGP)double-curved shallow nanoshell based on the flexoelectric effect and nonlocal strain gradient theory.Two coefficients that reduce or increase the stiffness of the nanoshell,including nonlocal and length-scale parameters,are considered to change along the nanoshell thickness direction,and three different porosity rules are novel points in this study.The nanoshell structure is placed on a Pasternak elastic foundation and is made up of three separate layers of material.The outermost layers consist of piezoelectric smart material with flexoelectric effects,while the core layer is composed of FGP material.Hamilton’s principle was used in conjunction with a unique refined higher-order shear deformation theory to derive general equilibrium equations that provide more precise outcomes.The Navier and Galerkin-Vlasov methodology is used to get the static bending characteristics of nanoshells that have various boundary conditions.The program’s correctness is assessed by comparison with published dependable findings in specific instances of the model described in the article.In addition,the influence of parameters such as flexoelectric effect,nonlocal and length scale parameters,elastic foundation stiffness coefficient,porosity coefficient,and boundary conditions on the static bending response of the nanoshell is detected and comprehensively studied.The findings of this study have practical implications for the efficient design and control of comparable systems,such as micro-electromechanical and nano-electromechanical devices. 展开更多
关键词 Analytical solution Flexoelectric effect Nonlocal strain gradient theory Static bending of nanoshell
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Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment
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作者 Zhao-Jun Zhang Wen-Wei Wang +4 位作者 Jing-Shui Zhen Bo-Cheng Li De-Cheng Cai Yang-Yang Du Hui Huang 《Structural Durability & Health Monitoring》 EI 2025年第1期105-123,共19页
This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment z... This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment zone.An experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was proposed.The composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab specimens.Two methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel beams.The experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal support.In contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading process.As the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan section.When the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span section.Since GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span section.All test specimens experienced compressive failure of concrete at the mid-span section.Calculation results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support section.The proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs. 展开更多
关键词 Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model
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Discrete Numerical Study on Type II Fracture of Partially Detached Concrete Panels in Cold Region
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作者 Huayi Zhang Maobin Song +2 位作者 Lei Shen Nizar Faisal Alkayem Maosen Cao 《Structural Durability & Health Monitoring》 EI 2025年第1期167-191,共25页
When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on ... When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the BSS.In order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during con-struction,the influence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefficient on the bending stiffness are analyzed parametrically by the numerical simula-tion technology based on an actual project.The calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical simulation.Then,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction plans.Moreover,the optimal construction plan of concrete placementfirst and then prestress-tensioning is proposed. 展开更多
关键词 Beam-string structure(BSS) concrete-filled steel tube(CFST) bending stiffness timing of concrete placement prestress-tensioning
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Springback Behavior and Biocompatibility inβ-Type Ti-Mo-O Alloys
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作者 Cheng Ren Xiaohua Min +1 位作者 Sujie Zhang Weiqiang Wang 《Acta Metallurgica Sinica(English Letters)》 2025年第2期313-326,共14页
Ti-Mo-O alloys were used to analyze the effect of Mo and O contents on the mechanical compatibility and biocompatibility.The bending modulus,bending yield strength and springback ratio of the alloys were evaluated by ... Ti-Mo-O alloys were used to analyze the effect of Mo and O contents on the mechanical compatibility and biocompatibility.The bending modulus,bending yield strength and springback ratio of the alloys were evaluated by using three-point bending tests and bending load-unloading tests.The biocompatibility was investigated by the adhesion,proliferation and the alkaline phosphatase(ALP)activity of mouse osteoblast-like cells(MC3T3-E1).The results showed that the bending modulus and bending yield strength first were increased and then decreased with the increase in Mo content,while the springback ratio exhibited an opposite trend to the bending modulus.With the increase in O content,the bending modulus remained almost constant,while the bending yield strength was increased.The springback ratio exhibited a similar trend to the bending yield strength.The in vitro biological experiments showed that the Ti-Mo-O alloys had excellent biocompatibility due to the formed stable oxide films on their surface.With the increase in O and Mo contents,the TiO_(2)-MoO_(2)oxide film became denser.Combining with mechanical compatibility and biocompatibility,the Ti-15Mo-0.2O and Ti-15Mo-0.3O alloys were more suitable for the biomedical application of spinal fixation device. 展开更多
关键词 β-type titanium alloys Bending modulus Bending yield strength SPRINGBACK BIOCOMPATIBILITY
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Strength of parrot fight feathers is a function of positionon the wing
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作者 Denis Charles Deeming Connor J.Hutchings +1 位作者 Fern G.Seaward Adrian M.Goodman 《Current Zoology》 2025年第2期212-222,共11页
Powered fight in birds is reliant on feathers forming an aerodynamic surface that resists air pressures.Many basic aspects of feather functionality are unknown,which hampers our understanding of wing function in birds... Powered fight in birds is reliant on feathers forming an aerodynamic surface that resists air pressures.Many basic aspects of feather functionality are unknown,which hampers our understanding of wing function in birds.This study measured the dimensions of primary and secondaryfight feathers of 19 species of parrots.The maximum force the feathers could withstand from below was also measured to mimic the pressuresexperienced during a downstroke.The analysis tested whether:(1)feather dimensions differed along the wing and among secondary and primary remiges;(2)the force that feathers could withstand varied among the remiges;and(3)there would be isometric relationships with bodymass for feather characteristics.The results show that body mass signifcantly affected vane width,rachis thickness,maximum force,and ultimate bending moment,but the relationship for feather length only approached signifcance.Many of the proximal secondary feathers showedsignifcantly lower values relative to the frst primary,whereas for distal primaries the values were greater.There were isometric relationships forforce measurements of primary and secondary feathers with body mass,but there was positive allometry for feather lengths and vane widths.The forces feathers can withstand vary along the wing may be a proxy for the aerodynamic properties of the feathers in situ.Broader taxonomicstudies that explore these topics are required for other species representing a range of different orders.A better understanding of the functionality of feathers will improve our understanding of how avian fight works particularly considering the variety in fight style and wing shape in birds. 展开更多
关键词 bending moment dimensions FEATHER force primary SECONDARY
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Bending Characteristics of Folded Multi-celled Tubes with Square and Circular Section Geometries
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作者 Rui Liang Fengxiang Xu +3 位作者 Zhen Zou Xiaoqiang Niu Xuebang Tang Tingpeng Li 《Acta Mechanica Solida Sinica》 2025年第1期125-141,共17页
This research investigates the bending response of folded multi-celled tubes(FMTs)fabricated by folded metal sheets.A three-point bending test for FMTs with circular and square sections is designed and introduced.The ... This research investigates the bending response of folded multi-celled tubes(FMTs)fabricated by folded metal sheets.A three-point bending test for FMTs with circular and square sections is designed and introduced.The base numerical models are correlated with physical experiments and a static crashworthiness analysis of six FMT configurations to assess their energy absorption characteristics.The influences of thickness,sectional shape,and load direction on the bending response are studied.Results indicate that increasing the thickness of the tube and radian of the inner tube enhances the crashworthiness performance of FMT,yielding a 20.50%increase in mean crushing force,a 55.53%increase in specific energy absorption,and an 18.05%decrease in peak crushing force compared to traditional multi-celled tubes(TMTs).A theoretical analysis of the specific energy absorption indicates that FMTs outperform TMTs,particularly when the peak crushing force is prominent.This study highlights the innovative and practical potential of FMTs to improve the crashworthiness of thin-walled structures. 展开更多
关键词 BENDING Folded Multi-celled tube Energy absorption Numerical
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A ComputationalModeling on Flow Bifurcation and Energy Distribution through a Loosely Bent Rectangular Duct with Vortex Structure
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作者 Rabindra NathMondal Giulio Lorenzini +1 位作者 Sidhartha Bhowmick Sreedham Chandra Adhikari 《Frontiers in Heat and Mass Transfer》 2025年第1期249-278,共30页
The present study investigates the non-isothermal flow and energy distribution through a loosely bent rectangular duct using a spectral-based numerical approach over a wide range of the Dean number 0<Dn≤3000.Unlik... The present study investigates the non-isothermal flow and energy distribution through a loosely bent rectangular duct using a spectral-based numerical approach over a wide range of the Dean number 0<Dn≤3000.Unlike previous research,this work offers novel insights by conducting a grid-point-specific velocity analysis and identifying new bifurcation structures.The study reveals how centrifugal and buoyancy forces interact to produce steady,periodic,and chaotic flow regimes significantly influencing heat transfer performance.The Newton-Raphson method is employed to explore four asymmetric steady branches,with vortex solutions ranging from 2-to 12 vortices.Unsteady flow characteristics are analyzed exquisitely by performing time-advancement of the solutions and the flow regimes are shown as a percentage of total flow with longitudinal vortex generation.Axial flow,secondary flow,and temperature profiles have been depicted in accordance with Dn to wander the flow pattern,and it is predicted that the time-dependent flow(TDF)consists of asymmetric 2-to 10-vortex solutions.The significant findings of this study include the axial displacement of the circulations due to the influence of the time-varying temperature dispersal applied along the wall.Chaotic flows,which dominate the higher Dean number range,are shown to enhance heat convection due to increased fluid mixing.A detailed comparison with prior research demonstrates the advantages of this approach,particularly in capturing complex non-linear behaviors.The findings of this study provide practical guidelines for optimizing duct designs to maximize heat transfer and suggest future research directions,such as using nanofluids or studying Magneto-hydrodynamics in the same configuration. 展开更多
关键词 Bending duct steady solutions time-advancement energy distribution VORTEX
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Texture-dependent bending behaviors of extruded AZ31 magnesium alloy plates
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作者 Kecheng Zhou Xiaochuan Sun +6 位作者 Hongwei Wang Xiaodan Zhang Ding Tang Weiqin Tang Yaodong Jiang Peidong Wu Huamiao Wang 《Journal of Magnesium and Alloys》 2025年第8期3617-3631,共15页
The relatively insufficient knowledge of the deformation behavior has limited the wide application of the lightest structure material-Mg alloys.Among others,bending behavior is of great importance because it is unavoi... The relatively insufficient knowledge of the deformation behavior has limited the wide application of the lightest structure material-Mg alloys.Among others,bending behavior is of great importance because it is unavoidably involved in various forming processes,such as folding,stamping,etc.The hexagonal close-packed structure makes it even a strong texture-dependent behavior and even hard to capture and predict.In this regard,the bending behaviors are investigated in terms of both experiments and simulations in the current work.Bending samples with longitudinal directions inclined from the transverse direction by different angles have been prepared from an extruded AZ31 plate,respectively.The moment-curvature curves and strain distribution have been recorded in the four-point bending tests assisted with an in-situ digital image correlation(DIC)system.A crystal-plasticity-based bending-specific approach named EVPSC-BEND was applied to bridge the mechanical response to the microstructure evolution and underlying deformation mechanisms.The flow stress,texture,twin volume fraction,stress distribution,and strain distribution evolve differently from sample to sample,manifesting strong texture-dependent bending behaviors.The underlying mechanisms associated with this texture dependency,especially the occurrence of both twinning and detwinning during the monotonic bending,are carefully discussed.Besides,the simulation has been conducted to reveal the moment-inclination angle relation of the investigated AZ31 extruded plate in terms of the polar coordinate,which intuitively shows the texture-dependent behaviors.Specifically,the samples with longitudinal directions parallel to the extruded direction bear the biggest initial yielding moment. 展开更多
关键词 Magnesium alloy Bending Texture-dependency Crystal plasticity Twinning and detwinning
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A comprehensive review of experimental studies on shear behavior of bolted rock joints with varying rock joint and bolt parameters and normal stress
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作者 Chang Zhou Zhenwei Lang +3 位作者 Shun Huang Qinghong Dong Yanzhi Wang Wenbo Zheng 《Deep Underground Science and Engineering》 2025年第2期189-209,共21页
The shear characteristics of bolted rock joints are crucial for the stability of tunneling and mining,particularly in deep underground engineering,where rock bolt materials are exposed to high stress,water pressure,an... The shear characteristics of bolted rock joints are crucial for the stability of tunneling and mining,particularly in deep underground engineering,where rock bolt materials are exposed to high stress,water pressure,and engineering disturbance.However,due to the complex interaction between bolted rock joints and various geological contexts,many challenges and unsolved problems arise.Therefore,more investigation is needed to understand the shear performance of bolted joints in the field of deep underground engineering.This study presents a comprehensive review of research findings on the responses of bolted joints subjected to shearing under different conditions.As is revealed,the average shear strength of bolted rock joints increases linearly with the normal stress and increases with the compressive strength of rock until it reaches a stable value.The joint roughness coefficient(JRC)affects the contact area,friction force,shear strength,bending angle,and axial force of bolted rock joints.A mathematical function is proposed to model the relationship between JRC,normal load,and shear strength.The normal stress level also influences the deformation model,load-carrying capacity,and energy absorption ratio of bolts within bolted rock joints,and can be effectively characterized by a two-phase exponential equation.Additionally,the angle of the bolts affects the ratio of tensile and shear strength of the bolts,as well as the mechanical behavior of both bolted rock joints and surrounding rock,which favors smaller angles.This comprehensive review of experimental data on the shear behavior of bolted rock joints offers valuable theoretical insights for the development of advanced shear devices and further pertinent investigations. 展开更多
关键词 bending angle rock bolt rock fracture ROUGHNESS shear resistance
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An embedded piezoelectric actuator for active vibration control:Concept,modeling,simulation,and investigation
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作者 Rui QI Liang WANG +3 位作者 Jiamei JIN Lusheng YUAN Ziyu SHEN Yuning GE 《Chinese Journal of Aeronautics》 2025年第4期244-256,共13页
Piezoelectric active vibration control holds paramount importance in space structures.An embedded piezoelectric actuator with a sandwich configuration is proposed,which enhances control accuracy by integrating various... Piezoelectric active vibration control holds paramount importance in space structures.An embedded piezoelectric actuator with a sandwich configuration is proposed,which enhances control accuracy by integrating various components.Firstly,the electromechanical coupling characteristics of the actuator are revealed,and the model is established.Secondly,the equivalent model of a cylindrical cantilever beam is investigated as the object,and the feasibility of the vibration control of the actuator is verified by simulation.Finally,the prototype comprised of two actuators,which respectively use the proposed embedded actuators for producing the vibration and suppressing the vibration,is developed,and the measurement system is constructed.Experimental results demonstrate the excellent control efficiency in two orthogonal directions,achieving a minimum vibration amplitude control of 0.00102 mm and a maximum vibration control of-42.74 d B.The integrated structure offers fast response,lightness,adaptability,and high control efficiency,which is conducive to enhancing the vibration control. 展开更多
关键词 Piezoelectric actuators Vibration control Disturbance rejection Actuators Bending vibration
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Research on Birdcage Buckling in the Armor Wire of A Damaged Umbilical Cable Under Compression and Bending Cyclic Load
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作者 CHEN Si-yuan DENG Yu +2 位作者 LIANG Xu DENG Xue-jiao WANG Zhen-kui 《China Ocean Engineering》 2025年第1期86-99,共14页
Buckling failure in submarine cables presents a prevalent challenge in ocean engineering.This work aims to explore the buckling behavior of umbilical cables with damaged sheaths subjected to compression and bending cy... Buckling failure in submarine cables presents a prevalent challenge in ocean engineering.This work aims to explore the buckling behavior of umbilical cables with damaged sheaths subjected to compression and bending cyclic loads.A finite element model is devised,incorporating a singular armor wire,a rigid core,and a damaged sheath.To scrutinize the buckling progression and corresponding deformation,axial compression and bending cyclic loads are introduced.The observations reveal that a reduction in axial compression results in a larger number of cycles before buckling ensues and progressively shifts the buckling position toward the extrados and fixed end.Decreasing the bending radius precipitates a reduction in the buckling cycle number and minimizes the deformation in the armor wire.Furthermore,an empirical model is presented to predict the occurrence of birdcage buckling,providing a means to anticipate buckling events and to estimate the requisite number of cycles leading to buckling. 展开更多
关键词 umbilical cable armor wire birdcage buckling bending cycle damaged sheath
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Experimental study on unsteady flow of hydraulic conveying of a single coarse particle through a 90°bend
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作者 Hui Cheng Hong Xiong +4 位作者 Yuxiang Chen Hong Zhu Chunliang Yu Guodong Zheng Yiyang Xing 《Acta Mechanica Sinica》 2025年第5期93-103,共11页
Bends contribute to a flexible layout of pipeline system,but also lead to intensive energy costs due to the complex flow characteristic.This experimental study is conducted to investigate the impact of a single coarse... Bends contribute to a flexible layout of pipeline system,but also lead to intensive energy costs due to the complex flow characteristic.This experimental study is conducted to investigate the impact of a single coarse particle on the flow field in a bend.The velocity profiles of fluid on the axial symmetry plane of the bend are measured using time-resolved particle image velocimetry.The flow structures are extracted using the proper orthogonal decomposition method.The results reveal that there is a shear-layer flow in the bend during the transportation.With the increase in particle size,the particle has a dominant influence on the flow energy distribution of the overall flow.The impact of particles on the first few energetic flows is mainly in the latter part of the transportation,both temporally and spatially.As the particle size decreases,the most energetic unsteady flow within the bend changes from the convective flow to the flow of the shear layer. 展开更多
关键词 Hydraulic conveying BEND Flow characteristic Particle image velocimetry Proper orthogonal decomposition
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基于TCGA数据库探讨BEND5表达对膀胱癌患者生存及癌细胞迁移能力的影响
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作者 李智强 陈从其 +4 位作者 陈锦添 陈伟 董菲艳 周素娟 林云侨 《福建医药杂志》 2025年第7期1-5,共5页
目的探讨膀胱癌组织与癌旁组织中BEN结构域蛋白5(BEND5)表达差异及BEND5对膀胱癌细胞迁移能力和雷帕霉素靶蛋白(mTOR)通路的影响。方法利用癌症基因组图集(TCGA)数据库分析BEND5表达与膀胱癌患者生存的关系;收集40例膀胱癌患者的癌及癌... 目的探讨膀胱癌组织与癌旁组织中BEN结构域蛋白5(BEND5)表达差异及BEND5对膀胱癌细胞迁移能力和雷帕霉素靶蛋白(mTOR)通路的影响。方法利用癌症基因组图集(TCGA)数据库分析BEND5表达与膀胱癌患者生存的关系;收集40例膀胱癌患者的癌及癌旁组织,采用荧光定量PCR(qPCR)及蛋白免疫印迹法(Western blot,WB)检测BEND5mRNA及蛋白表达差异;膀胱癌5637和UMUC3细胞转染BEND5-siRNA后,划痕-愈合实验检测迁移能力的差异,WB法检测mTOR通路蛋白及波形蛋白(Vimentin)表达差异。结果通过TCGA分析发现,在膀胱癌中BEND5表达下调,且低表达的膀胱癌患者生存率更低。实验显示膀胱癌组织中BEND5 mRNA和蛋白表达均低于癌旁组织;沉默BEND5提高了膀胱癌细胞的迁移能力,并上调mTOR通路蛋白及波形蛋白表达。结论在膀胱癌组织中BEND5基因低表达,可能通过激活mTOR通路及促进癌细胞迁移的方式降低患者的生存率。 展开更多
关键词 膀胱癌 BEND5 抗癌 mTOR通路 TCGA数据库
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A novel Al-alloyed press-hardening steel with superior mechanical and antioxidant properties
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作者 Feng-kun Lin Xiao-ming Zhang +1 位作者 Yuan-xiang Zhang Guo Yuan 《Journal of Iron and Steel Research International》 2025年第4期1045-1060,共16页
A novel Al-alloyed press-hardening steel(PHS)was developed,which exhibits excellent tensile,bending and antioxidation properties.Al is a ferrite-forming element that can hinder the formation of cementite and enhance t... A novel Al-alloyed press-hardening steel(PHS)was developed,which exhibits excellent tensile,bending and antioxidation properties.Al is a ferrite-forming element that can hinder the formation of cementite and enhance the stability of austenite.The incorporation of Al not only induces the formation of ferrite within martensitic matrix but also enhances the stability of retained austenite(RA).The microstructure of novel steel consists of martensite,ferrite,and RA after press hardening.Investigations into the role of Al in RA development were supported by thermo-kinetic calculations.The simultaneous introduction of ferrite and RA into the martensitic matrix via tailored chemical compositions significantly enhances the elongation and bending toughness of the novel PHS.Additionally,Al can form a dense Al oxide at the bottom of oxide layer,resulting in the improved antioxidant properties.Compared to 22MnB5 steel,it is an exciting discovery as there is a significant improvement in total elongation and bending toughness of novel PHS without compromising strength.The novel PHS,with its exceptional balance of strength and ductility,will play a crucial role in reducing weight when it replaces the existing class 22MnB5 PHS in different structural components of vehicle bodies. 展开更多
关键词 Al-alloyed steel Press hardened steel Tensile property Bending toughness Antioxidant property
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Fracture characteristics and process zone evolution in sandstone under freeze-thaw cycles
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作者 MeiLu Yu ZhongWen Wang +5 位作者 Ding Ma JinJin Ge YaTing Wang HaoTian Xie GenShui Wu YaoYao Meng 《Research in Cold and Arid Regions》 2025年第4期217-228,共12页
This study investigates the fracture characteristics and the fracture process zone(FPZ)of mode I fracture in sandstone,aiming to analyze the propagation behaviors of mode I crack under different freeze-thaw cycles.Sem... This study investigates the fracture characteristics and the fracture process zone(FPZ)of mode I fracture in sandstone,aiming to analyze the propagation behaviors of mode I crack under different freeze-thaw cycles.Semicircular bending tests(SCB)were conducted using different freeze-thaw cycles to evaluate mode I fracture toughness,FPZ dynamics,and macroscopic microscopic features.Digital image correlation(DIC)and scanning electron microscopy(SEM)techniques were employed for detailed analysis.Experimental results reveal that freeze-thaw cycling leads to the widening of both preexisting and newly formed microcracks between internal particles.Under external loading,crack propagation deviates from prefabricated paths,forming serrated crack patterns.The FPZ initiates at the prefabricated crack tip and extends toward the loading end,exhibiting an arcshaped tip shape.The FPZ length increases with loading but decreases after reaching a peak value.With additional freeze-thaw cycles,the maximum FPZ length first increases and then diminishes. 展开更多
关键词 Freeze-thaw cycles Fracture toughness Semi-circular bending tests Fracture process zone
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Deformation mechanism of a novel pipe-roof composite slab:An experimental and theoretical investigation
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作者 LU Bo JIA Peng-jiao +3 位作者 ZHAO Wen NI Peng-peng BAI Qian CHENG Cheng 《Journal of Central South University》 2025年第3期1044-1059,共16页
Steel tube slab (STS) structure, a novel pipe-roof structure, of which steel tubes are connected with flange plates, bolts and concrete, is an increasingly popular supporting structure for underground space developmen... Steel tube slab (STS) structure, a novel pipe-roof structure, of which steel tubes are connected with flange plates, bolts and concrete, is an increasingly popular supporting structure for underground space development. Whilst the load-bearing of pipe-roof structures has been the subject of much research, uncertainties of deformation mechanism and the derivation of reliable calculation methods remain a challenge. For efficient design and wider deployment, this paper presents a bidirectional bending test to investigate the bending stiffnesses, load capacities and deformation mechanisms. The results show that the STS specimens exhibit good ductility and experience bending failure, and their deformation curves follow a half-sine wave upon loading. On this basis, the development of an STS composite slab deformation prediction model is proposed, along with the estimation for its bending stiffness. Theoretical predictions are shown to be in good agreement with the experimental measurements, with a maximum error of less than 15%. The outcomes of this investigation can provide references for the design and application of STS structures. 展开更多
关键词 steel tube slab deformation characteristics bending stiffness theoretical model
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